The network for 'macromolecule catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macromolecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
rpt-2 Protein RPT-2 0.857
rpt-5 Protein RPT-5 0.759
goa-1 Protein GOA-1 0.651
rpn-7 Protein RPN-7 0.636
vav-1 Protein VAV-1 0.624
taf-9 Protein TAF-9 0.610
rpn-12 Protein RPN-12 0.609
unc-112 Protein UNC-112 0.554
unc-52 Protein UNC-52 0.551
cdc-48.2 Protein CDC-48.2 0.550
msh-6 Protein MSH-6 0.536
pas-4 Protein PAS-4 0.535
egl-30 Protein EGL-30 0.524
daf-21 Protein DAF-21 0.510
pas-1 Protein PAS-1 0.503
atx-3 Protein ATX-3 0.494
col-182 Protein COL-182 0.472
F46C5.9 Protein F46C5.9 0.451
lmn-1 Protein LMN-1 0.437
unc-9 Protein UNC-9 0.436
spn-4 Protein SPN-4 0.405
let-99 Protein LET-99 0.393
plc-1 Protein PLC-1 0.392
dpy-4 Protein DPY-4 0.386
col-104 Protein COL-104 0.354
col-133 Protein COL-133 0.349
rnr-1 Protein RNR-1 0.344
F46F11.6 Protein F46F11.6 0.342
inx-12 Protein INX-12 0.334
dlc-1 Protein DLC-1 0.331
pry-1 Protein PRY-1 0.330
sel-2 Protein SEL-2 0.329
hgrs-1 Protein HGRS-1 0.328
par-5 Protein PAR-5 0.322
pbs-6 Protein PBS-6 0.320
ida-1 Protein IDA-1 0.316
egl-13 Protein EGL-13 0.316
col-119 Protein COL-119 0.316
rbx-1 Protein RBX-1 0.314
unc-54 Protein UNC-54 0.313
taf-5 Protein TAF-5 0.311
lin-45 Protein LIN-45 0.309
rpn-6.1 Protein RPN-6.1 0.308
mig-2 Protein MIG-2 0.306
R05H5.5 Protein R05H5.5 0.304
col-180 Protein COL-180 0.304
egl-15 Protein EGL-15 0.300
ced-9 Protein CED-9 0.299
K10C9.3 Protein K10C9.3 0.299
col-93 Protein COL-93 0.299
dim-1 Protein DIM-1 0.298
rpt-3 Protein RPT-3 0.296
lin-7 Protein LIN-7 0.296
tba-2 Protein TBA-2 0.292
col-157 Protein COL-157 0.285
let-60 Protein LET-60 0.285
imb-2 Protein IMB-2 0.284
npp-22 Protein NPP-22 0.284
zyg-9 Protein ZYG-9 0.283
unc-53 Protein UNC-53 0.283
unc-23 Protein UNC-23 0.272
CELE_C25A1.4 Protein C25A1.4 0.268
C43H8.2 Protein C43H8.2 0.267
col-2 Protein COL-2 0.264
col-84 Protein COL-84 0.261
col-181 Protein COL-181 0.260
egl-36 Protein EGL-36 0.260
R90.1 Protein R90.1 0.260
col-125 Protein COL-125 0.260
mig-5 Protein MIG-5 0.257
pbs-4 Protein PBS-4 0.255
egl-5 Protein EGL-5 0.254
jnk-1 Protein JNK-1 0.254
rpn-3 Protein RPN-3 0.254
gck-2 Protein GCK-2 0.253
col-167 Protein COL-167 0.253
vps-32.1 Protein VPS-32.1 0.252
ZK1248.11 Protein ZK1248.11 0.249
Y42H9AR.4 Protein Y42H9AR.4 0.247
pbs-5 Protein PBS-5 0.246
kin-3 Protein KIN-3 0.241
T14G8.3 Protein T14G8.3 0.238
tag-135 Protein TAG-135 0.238
E04D5.1 Protein E04D5.1 0.237
tat-1 Protein TAT-1 0.233
fnta-1 Protein FNTA-1 0.233
stam-1 Protein STAM-1 0.230
C13F10.6 Protein C13F10.6 0.230
mec-2 Protein MEC-2 0.230
pbs-7 Protein PBS-7 0.229
deb-1 Protein DEB-1 0.229
bli-2 Protein BLI-2 0.225
unc-6 Protein UNC-6 0.224
vps-53 Protein VPS-53 0.223
ttyh-1 Protein TTYH-1 0.220
pbs-1 Protein PBS-1 0.220
rpt-4 Protein RPT-4 0.219
vpr-1 Protein VPR-1 0.218
col-144 Protein COL-144 0.217
daf-1 Protein DAF-1 0.217
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Danio rerio
Name Description Probability Func Analog Organism
chd chordin 0.434
psmb1 proteasome (prosome, macropain) subunit, beta type, 1 0.314
psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.281
crabp2a cellular retinoic acid binding protein 2, a 0.230
pcna proliferating cell nuclear antigen 0.195
smad5 MAD homolog 5 (Drosophila) 0.184
psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.178
psma6a proteasome (prosome, macropain) subunit, alpha type, 6a 0.175
zgc:92775 zgc:92775 0.154
bactin2 bactin2 0.139
aurkb aurora kinase B 0.130
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.110
wnt8b wingless-type MMTV integration site family, member 8b 0.097
psmb3 proteasome (prosome, macropain) subunit, beta type, 3 0.095
ilk integrin linked kinase 0.095
itgb1b integrin, beta 1b 0.094
psma8 proteasome (prosome, macropain) subunit, alpha type, 8 0.093
itgb1b.2 integrin, beta 1b.2 0.091
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.090
hspa5 heat shock protein 5 0.087
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.086
gpib glucose phosphate isomerase b 0.075
psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.075
ube2d1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.074
psmb7 proteasome (prosome, macropain) subunit, beta type, 7 0.073
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.070
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.066
psmd4b proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b 0.065
hhip hedgehog interacting protein 0.064
zgc:123326 zgc:123326 0.063
ran ras-related nuclear protein 0.062
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.058
nudc nuclear distribution gene C homolog 0.056
vegfc vascular endothelial growth factor c 0.054
ptch2 patched 2 0.052
zgc:110113 zgc:110113 0.052
psmc3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.052
fstl1b follistatin-like 1b 0.052
pcdh8 protocadherin 8 0.051
gsc goosecoid 0.050
actn3b actinin alpha 3b 0.050
zgc:174506 zgc:174506 0.049
sox32 SRY-box containing gene 32 0.049
rnaset2 ribonuclease T2 0.047
mobkl3 MOB1, Mps One Binder kinase activator-like 3 (yeast) 0.047
pou2f1a POU class 2 homeobox 1a 0.047
chd7 chromodomain helicase DNA binding protein 7 0.046
acvr1b activin A receptor, type IB 0.046
tnnt3a troponin T3a, skeletal, fast 0.046
psmb4 proteasome (prosome, macropain) subunit, beta type, 4 0.045
zgc:103652 zgc:103652 0.044
psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.043
gbx2 gastrulation brain homeo box 2 0.042
ahcyl1 S-adenosylhomocysteine hydrolase-like 1 0.042
bub3 BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.041
ctsz cathepsin Z 0.041
plcg1 phospholipase C, gamma 1 0.041
bhmt betaine-homocysteine methyltransferase 0.040
blmh bleomycin hydrolase 0.040
ck2b casein kinase 2 beta 0.040
zgc:91910 zgc:91910 0.039
myog myogenin 0.039
bag6 BCL2-associated athanogene 6 0.038
crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.037
tmem2 transmembrane protein 2 0.037
fgf8a fibroblast growth factor 8 a 0.037
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.036
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.036
csnk1da casein kinase 1, delta a 0.036
psmc1b proteasome (prosome, macropain) 26S subunit, ATPase, 1b 0.036
smad2 MAD homolog 2 (Drosophila) 0.036
zgc:55671 zgc:55671 0.035
cnot8 CCR4-NOT transcription complex, subunit 8 0.035
spry4 sprouty (Drosophila) homolog 4 0.035
nrg2a neuregulin 2a 0.035
bsdc1 BSD domain containing 1 0.035
atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide 0.035
smndc1 survival motor neuron domain containing 1 0.034
cdc25 cell division cycle 25 homolog 0.034
tnni2a.4 troponin I, skeletal, fast 2a.4 0.033
smyhc1l slow myosin heavy chain 1, like 0.033
snai1a snail homolog 1a (Drosophila) 0.033
ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.032
zgc:112254 zgc:112254 0.032
psma1 proteasome (prosome, macropain) subunit, alpha type, 1 0.032
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.032
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.032
rab5aa RAB5A, member RAS oncogene family, a 0.032
senp3a SUMO1/sentrin/SMT3 specific peptidase 3a 0.031
psma4 proteasome (prosome, macropain) subunit, alpha type, 4 0.031
im:6902407 im:6902407 0.031
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.030
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.030
bon bonnie and clyde 0.030
snrpb2 small nuclear ribonucleoprotein polypeptide B2 0.030
cobl cordon-bleu homolog (mouse) 0.030
zgc:101661 zgc:101661 0.030
eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) 0.029
LOC100330405 transmembrane protein 176B-like 0.029
etv5b ets variant 5b 0.029
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.903
Dcr-2 Dicer-2 0.853
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.793
Fcp1 CG12252 gene product from transcript CG12252-RA 0.696
Aos1 CG12276 gene product from transcript CG12276-RA 0.692
tsr twinstar 0.688
ctp cut up 0.685
Mad Mothers against dpp 0.683
shg shotgun 0.658
msps mini spindles 0.657
Tak1 TGF-beta activated kinase 1 0.633
ci cubitus interruptus 0.607
tral trailer hitch 0.601
EcR Ecdysone receptor 0.560
Prosbeta5 Proteasome beta5 subunit 0.552
gwl greatwall 0.528
cdc2 CG5363 gene product from transcript CG5363-RA 0.523
Prosbeta2 Proteasome beta2 subunit 0.518
p53 CG33336 gene product from transcript CG33336-RB 0.497
UbcD2 Ubiquitin conjugating enzyme 2 0.486
CkIIalpha Casein kinase II alpha subunit 0.479
Pros26.4 Proteasome 26S subunit subunit 4 ATPase 0.478
Rpn11 CG18174 gene product from transcript CG18174-RA 0.471
tefu telomere fusion 0.467
pie pineapple eye 0.465
sgg shaggy 0.464
Cul-4 Cullin-4 0.462
dap dacapo 0.458
yki yorkie 0.454
ptc patched 0.453
Akt1 CG4006 gene product from transcript CG4006-RA 0.448
twin CG31137 gene product from transcript CG31137-RB 0.439
phl pole hole 0.416
rin rasputin 0.404
CG11347 CG11347 gene product from transcript CG11347-RE 0.403
dco discs overgrown 0.398
kis kismet 0.397
Rpn9 CG10230 gene product from transcript CG10230-RB 0.390
Pros29 Proteasome 29kD subunit 0.390
smt3 CG4494 gene product from transcript CG4494-RA 0.385
lqf liquid facets 0.367
Smox Smad on X 0.365
Fhos CG42610 gene product from transcript CG42610-RC 0.362
Top1 Topoisomerase 1 0.361
AttA Attacin-A 0.359
rok Rho-kinase 0.358
Prosbeta3 Proteasome beta3 subunit 0.353
scny scrawny 0.342
Cap-G CG34438 gene product from transcript CG34438-RF 0.337
Hel25E Helicase at 25E 0.336
Fmr1 CG6203 gene product from transcript CG6203-RC 0.335
Atg1 Autophagy-specific gene 1 0.335
eff effete 0.332
E(z) Enhancer of zeste 0.319
dos daughter of sevenless 0.311
rl rolled 0.311
CG4680 CG4680 gene product from transcript CG4680-RA 0.310
N Notch 0.308
Rpt1 CG1341 gene product from transcript CG1341-RA 0.307
CycB Cyclin B 0.303
B52 CG10851 gene product from transcript CG10851-RB 0.299
Rpt3 CG16916 gene product from transcript CG16916-RA 0.297
Prosalpha5 Proteasome alpha5 subunit 0.292
G-salpha60A G protein salpha 60A 0.290
SAK Sak kinase 0.287
Tbp-1 Tat-binding protein-1 0.280
key kenny 0.274
p38b CG7393 gene product from transcript CG7393-RA 0.271
Txl Thioredoxin-like 0.271
babo baboon 0.268
RpS3A Ribosomal protein S3A 0.263
CG4030 CG4030 gene product from transcript CG4030-RA 0.261
RYBP Ring and YY1 Binding Protein 0.258
gig gigas 0.257
CSN5 COP9 complex homolog subunit 5 0.255
spn-A spindle A 0.254
fry furry 0.253
Cam Calmodulin 0.251
Prosbeta1 Proteasome beta1 subunit 0.248
InR Insulin-like receptor 0.248
Tab2 TAK1-associated binding protein 2 0.244
jub Ajuba LIM protein 0.244
grass Gram-positive Specific Serine protease 0.243
Pros26 Proteasome 26kD subunit 0.243
Rab5 Rab-protein 5 0.242
CG12321 CG12321 gene product from transcript CG12321-RA 0.239
Rpt4 CG3455 gene product from transcript CG3455-RA 0.238
Rpn5 CG1100 gene product from transcript CG1100-RA 0.232
Kr-h1 Kruppel homolog 1 0.229
Rab11 Rab-protein 11 0.229
sqh spaghetti squash 0.228
CdsA CDP diglyceride synthetase 0.226
Bj1 Bj1 protein 0.225
Cul-3 Cullin-3 0.225
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.223
simj simjang 0.223
Rack1 Receptor of activated protein kinase C 1 0.222
RagA CG11968 gene product from transcript CG11968-RA 0.217
Plc21C Phospholipase C at 21C 0.217
gbb glass bottom boat 0.216
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Ilk integrin linked kinase 0.977
Trp53 transformation related protein 53 0.977
Axin1 axin 1 0.969
Pten phosphatase and tensin homolog 0.956
Vcp valosin containing protein 0.955
Usp9x ubiquitin specific peptidase 9, X chromosome 0.949
Ccnb1 cyclin B1 0.932
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.918
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.910
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.899
Fgfr1 fibroblast growth factor receptor 1 0.886
Rbl2 retinoblastoma-like 2 0.881
Fgfr2 fibroblast growth factor receptor 2 0.876
Traf6 TNF receptor-associated factor 6 0.861
Gsk3b glycogen synthase kinase 3 beta 0.846
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.838
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.836
Dab1 disabled homolog 1 (Drosophila) 0.834
Cops2 COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) 0.829
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.807
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.802
Brca1 breast cancer 1 0.801
Cyld cylindromatosis (turban tumor syndrome) 0.794
Psen1 presenilin 1 0.792
Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.790
Smad7 MAD homolog 7 (Drosophila) 0.765
Apc adenomatosis polyposis coli 0.742
Htt huntingtin 0.738
Psmb7 proteasome (prosome, macropain) subunit, beta type 7 0.734
Rarb retinoic acid receptor, beta 0.723
Rxra retinoid X receptor alpha 0.721
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.709
Hif1a hypoxia inducible factor 1, alpha subunit 0.708
Fbn1 fibrillin 1 0.704
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.703
Sqstm1 sequestosome 1 0.701
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.696
Psmb4 proteasome (prosome, macropain) subunit, beta type 4 0.671
Ctnnd1 catenin (cadherin associated protein), delta 1 0.669
Pkd1 polycystic kidney disease 1 homolog 0.665
Cacybp calcyclin binding protein 0.663
Skp1a S-phase kinase-associated protein 1A 0.662
Clock circadian locomotor output cycles kaput 0.657
Cdk4 cyclin-dependent kinase 4 0.650
Psma3 proteasome (prosome, macropain) subunit, alpha type 3 0.648
Psma1 proteasome (prosome, macropain) subunit, alpha type 1 0.646
Kif11 kinesin family member 11 0.643
Inpp5d inositol polyphosphate-5-phosphatase D 0.637
Smad1 MAD homolog 1 (Drosophila) 0.630
Tjp1 tight junction protein 1 0.624
Apoe apolipoprotein E 0.617
Add1 adducin 1 (alpha) 0.617
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.611
Ccna2 cyclin A2 0.603
Cdk1 cyclin-dependent kinase 1 0.600
Nf1 neurofibromatosis 1 0.598
Arrb1 arrestin, beta 1 0.594
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.591
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.587
Mcl1 myeloid cell leukemia sequence 1 0.583
Atf2 activating transcription factor 2 0.578
Anapc2 anaphase promoting complex subunit 2 0.578
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.575
Lmnb1 lamin B1 0.574
Psma6 proteasome (prosome, macropain) subunit, alpha type 6 0.572
Hdac6 histone deacetylase 6 0.559
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.555
Cry2 cryptochrome 2 (photolyase-like) 0.552
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.550
Stat1 signal transducer and activator of transcription 1 0.549
Actn4 actinin alpha 4 0.549
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.541
Rrm2 ribonucleotide reductase M2 0.538
Stat6 signal transducer and activator of transcription 6 0.538
Psme4 proteasome (prosome, macropain) activator subunit 4 0.537
Ubc ubiquitin C 0.533
Ccne1 cyclin E1 0.533
Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 0.528
Ncor1 nuclear receptor co-repressor 1 0.520
Ncoa3 nuclear receptor coactivator 3 0.512
Akt1 thymoma viral proto-oncogene 1 0.508
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.506
Kpna1 karyopherin (importin) alpha 1 0.505
Tgfbr2 transforming growth factor, beta receptor II 0.501
Rara retinoic acid receptor, alpha 0.500
Casp3 caspase 3 0.500
Pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.499
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.498
Hsph1 heat shock 105kDa/110kDa protein 1 0.485
Aamp angio-associated migratory protein 0.482
Skil SKI-like 0.480
Usp22 ubiquitin specific peptidase 22 0.478
Egfr epidermal growth factor receptor 0.478
Sharpin SHANK-associated RH domain interacting protein 0.473
Psmb6 proteasome (prosome, macropain) subunit, beta type 6 0.471
Cops5 COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana) 0.470
Mmp9 matrix metallopeptidase 9 0.469
Thbs1 thrombospondin 1 0.469
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.468
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Rattus norvegicus
Name Description Probability Func Analog Organism
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.885
Psma3 proteasome (prosome, macropain) subunit, alpha type 3 0.789
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.591
Psmb2 proteasome (prosome, macropain) subunit, beta type 2 0.399
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.380
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.349
Psma4 proteasome (prosome, macropain) subunit, alpha type 4 0.338
Psmb3 proteasome (prosome, macropain) subunit, beta type 3 0.322
Eef2 eukaryotic translation elongation factor 2 0.317
Top2a topoisomerase (DNA) II alpha 0.271
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.267
Psma2 proteasome (prosome, macropain) subunit, alpha type 2 0.258
Gja1 gap junction protein, alpha 1 0.257
Psmb6 proteasome (prosome, macropain) subunit, beta type 6 0.246
Psmb5 proteasome (prosome, macropain) subunit, beta type 5 0.237
Ptges3 prostaglandin E synthase 3 (cytosolic) 0.213
Csnk1d casein kinase 1, delta 0.204
Ccnb1 cyclin B1 0.179
Vcp valosin-containing protein 0.178
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.171
Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.159
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.150
Cnbp CCHC-type zinc finger, nucleic acid binding protein 0.147
Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 0.135
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.131
Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.130
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.130
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.130
Eif4h eukaryotic translation initiation factor 4H 0.124
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.123
Rab11a RAB11a, member RAS oncogene family 0.112
Cops6 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) 0.108
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.106
B2m beta-2 microglobulin 0.104
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.101
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.100
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.097
Coro1b coronin, actin-binding protein, 1B 0.096
Begain brain-enriched guanylate kinase-associated 0.093
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.093
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.090
Syngr2 synaptogyrin 2 0.089
Eif4e eukaryotic translation initiation factor 4E 0.084
Pdia4 protein disulfide isomerase family A, member 4 0.084
Gfi1 growth factor independent 1 transcription repressor 0.084
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.083
Serinc1 serine incorporator 1 0.082
Psma1 proteasome (prosome, macropain) subunit, alpha type 1 0.082
Hprt1 hypoxanthine phosphoribosyltransferase 1 0.081
Psme2 proteasome (prosome, macropain) activator subunit 2 0.077
Mapk1 mitogen activated protein kinase 1 0.077
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.075
Dlg4 discs, large homolog 4 (Drosophila) 0.074
Calr calreticulin 0.073
Creld2 cysteine-rich with EGF-like domains 2 0.073
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.071
Igfals insulin-like growth factor binding protein, acid labile subunit 0.071
Dbp D site of albumin promoter (albumin D-box) binding protein 0.070
LOC100366237 prefoldin subunit 4-like 0.070
Ccnb2 cyclin B2 0.069
Gabrp gamma-aminobutyric acid (GABA-A) receptor, pi 0.069
Anxa1 annexin A1 0.069
Atp6v1f ATPase, H transporting, lysosomal V1 subunit F 0.069
Lamp2 lysosomal-associated membrane protein 2 0.067
Ube2c ubiquitin-conjugating enzyme E2C 0.067
Adam7 ADAM metallopeptidase domain 7 0.067
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.066
Jak2 Janus kinase 2 0.065
Rpe ribulose-5-phosphate-3-epimerase 0.065
Nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 0.064
Hk1 hexokinase 1 0.064
Cand1 cullin-associated and neddylation-dissociated 1 0.063
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.061
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.060
Zfand5 zinc finger, AN1-type domain 5 0.060
Lamc1 laminin, gamma 1 0.060
Arpc1b actin related protein 2/3 complex, subunit 1B 0.058
Ube2b ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae) 0.058
Pyy peptide YY (mapped) 0.058
Actn4 actinin alpha 4 0.058
Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.057
Cckbr cholecystokinin B receptor 0.056
Psmb7 proteasome (prosome, macropain) subunit, beta type 7 0.056
Tomm20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.056
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.056
Cyfip1 cytoplasmic FMR1 interacting protein 1 0.055
Pttg1 pituitary tumor-transforming 1 0.055
Otud7a OTU domain containing 7A 0.055
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.055
Actb actin, beta 0.054
Mtx2 metaxin 2 0.053
Cops2 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) 0.053
Lman1 lectin, mannose-binding, 1 0.053
Homer1 homer homolog 1 (Drosophila) 0.053
Egr1 early growth response 1 0.052
Hsp90b1 heat shock protein 90, beta, member 1 0.052
Smad7 SMAD family member 7 0.052
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.051
Gna15 guanine nucleotide binding protein, alpha 15 0.051
Vapa VAMP (vesicle-associated membrane protein)-associated protein A 0.051
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
POP2 Pop2p 0.986
MOT2 Mot2p 0.981
BRE5 Bre5p 0.981
RAD23 Rad23p 0.978
CDC48 Cdc48p 0.964
PRE2 Pre2p 0.958
DHH1 Dhh1p 0.954
SKI2 Ski2p 0.941
KEM1 Kem1p 0.928
HRT1 Hrt1p 0.922
RPT6 Rpt6p 0.908
HRD1 Hrd1p 0.896
ECM29 Ecm29p 0.870
DSK2 Dsk2p 0.862
CAF40 Caf40p 0.859
MAD2 Mad2p 0.857
PPH21 Pph21p 0.854
PRE1 Pre1p 0.850
DOC1 Doc1p 0.844
UBP15 Ubp15p 0.842
PPH22 Pph22p 0.842
RPT1 Rpt1p 0.840
RPN12 Rpn12p 0.839
RAD52 Rad52p 0.828
RRP6 Rrp6p 0.826
PRE10 Pre10p 0.802
BCK1 Bck1p 0.798
RPT5 Rpt5p 0.797
UBP6 Ubp6p 0.783
RPO21 Rpo21p 0.781
CSL4 Csl4p 0.772
RPT3 Rpt3p 0.772
CDC23 Cdc23p 0.771
SKI7 Ski7p 0.764
KSP1 Ksp1p 0.762
FYV10 Fyv10p 0.753
LSM1 Lsm1p 0.751
RPN10 Rpn10p 0.750
DFM1 Dfm1p 0.749
SCH9 Sch9p 0.749
OTU1 Otu1p 0.736
UFD2 Ufd2p 0.736
TOP1 Top1p 0.735
PAP2 Pap2p 0.735
CDC36 Cdc36p 0.716
MTR3 Mtr3p 0.705
PRE9 Pre9p 0.688
RRP45 Rrp45p 0.680
SWM1 Swm1p 0.678
TIF1 Tif1p 0.677
MCM21 Mcm21p 0.676
RFA1 Rfa1p 0.673
RPT4 Rpt4p 0.666
RPN6 Rpn6p 0.664
UFD1 Ufd1p 0.655
MND2 Mnd2p 0.638
PET309 Pet309p 0.634
CDC16 Cdc16p 0.626
PRE7 Pre7p 0.620
PAT1 Pat1p 0.619
UBR1 Ubr1p 0.618
CDC4 Cdc4p 0.615
SGV1 Sgv1p 0.613
SKI6 Ski6p 0.602
RPN7 Rpn7p 0.592
FOB1 Fob1p 0.591
PUP1 Pup1p 0.587
MSS11 Mss11p 0.584
UBX3 Ubx3p 0.582
CTF4 Ctf4p 0.579
SMC6 Smc6p 0.578
PRE6 Pre6p 0.577
MRE11 Mre11p 0.574
PMS1 Pms1p 0.573
GDB1 Gdb1p 0.565
NPL3 Npl3p 0.565
UBP3 Ubp3p 0.559
CDC39 Cdc39p 0.557
NUP170 Nup170p 0.553
RPT2 Rpt2p 0.551
UFD4 Ufd4p 0.551
CDC28 Cdc28p 0.540
ADE16 Ade16p 0.539
RRP43 Rrp43p 0.538
NMD2 Nmd2p 0.536
RRP46 Rrp46p 0.531
PRR1 Prr1p 0.531
UMP1 Ump1p 0.530
HRD3 Hrd3p 0.530
RPN1 Rpn1p 0.530
APC1 Apc1p 0.530
ELC1 Elc1p 0.529
SSE2 Sse2p 0.529
YOS9 Yos9p 0.524
MUD2 Mud2p 0.517
VPS36 Vps36p 0.516
MEC1 Mec1p 0.513
PUP3 Pup3p 0.512
APC9 Apc9p 0.511
RPN8 Rpn8p 0.510