The network for 'cellular macromolecule biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

Name Description Probability Func Analog Organism
pha-4 Protein PHA-4 0.990
egl-18 Protein EGL-18 0.987
hlh-2 Protein HLH-2 0.908
his-45 Protein HIS-45 0.850
ceh-20 Protein CEH-20 0.840
hcp-3 Protein HCP-3 0.817
lin-35 Protein LIN-35 0.811
cam-1 Protein CAM-1 0.799
nud-1 Protein NUD-1 0.778
his-1 Protein HIS-1 0.775
egl-13 Protein EGL-13 0.766
nhr-67 Protein NHR-67 0.764
csn-4 Protein CSN-4 0.764
lin-29 Protein LIN-29 0.749
unc-40 Protein UNC-40 0.728
dlk-1 Protein DLK-1 0.722
his-5 Protein HIS-5 0.706
rpn-1 Protein RPN-1 0.676
hsp-1 Protein HSP-1 0.670
elt-6 Protein ELT-6 0.663
smp-1 Protein SMP-1 0.647
his-31 Protein HIS-31 0.646
let-502 Protein LET-502 0.621
attf-2 Protein ATTF-2 0.613
rack-1 Protein RACK-1 0.611
asd-1 Protein ASD-1 0.607
zyg-1 Protein ZYG-1 0.602
egl-45 Protein EGL-45 0.598
his-16 Protein HIS-16 0.587
eftu-2 Protein EFTU-2 0.574
rps-2 Protein RPS-2 0.571
his-64 Protein HIS-64 0.566
eya-1 Protein EYA-1 0.563
F39B2.1 Protein F39B2.1 0.556
peb-1 Protein PEB-1 0.544
his-46 Protein HIS-46 0.543
mcm-7 Protein MCM-7 0.543
bet-1 Protein BET-1 0.539
tbb-1 Protein TBB-1 0.537
his-50 Protein HIS-50 0.524
rad-26 Protein RAD-26 0.518
pqn-59 Protein PQN-59 0.518
rpl-4 Protein RPL-4 0.504
scc-1 Protein SCC-1 0.496
fkh-2 Protein FKH-2 0.494
daf-1 Protein DAF-1 0.492
mep-1 Protein MEP-1 0.480
egl-27 Protein EGL-27 0.479
egl-46 Protein EGL-46 0.475
vab-3 Protein VAB-3 0.474
lin-12 Protein LIN-12 0.474
mcm-2 Protein MCM-2 0.467
unc-73 Protein UNC-73 0.467
sas-5 Protein SAS-5 0.466
mes-4 Protein MES-4 0.462
lin-53 Protein LIN-53 0.456
H06I04.1 Protein H06I04.1 0.455
sma-6 Protein SMA-6 0.451
zip-7 Protein ZIP-7 0.441
his-3 Protein HIS-3 0.438
mig-6 Protein MIG-6 0.435
cct-2 Protein CCT-2 0.433
aipl-1 Protein AIPL-1 0.433
ceh-58 Protein CEH-58 0.432
tba-1 Protein TBA-1 0.423
pry-1 Protein PRY-1 0.419
pmk-1 Protein PMK-1 0.417
tps-1 Protein TPS-1 0.416
F32E10.5 Protein F32E10.5 0.406
mel-11 Protein MEL-11 0.404
mix-1 Protein MIX-1 0.403
htz-1 Protein HTZ-1 0.395
H21P03.2 Protein H21P03.2 0.392
his-61 Protein HIS-61 0.390
rsp-1 Protein RSP-1 0.388
patr-1 Protein PATR-1 0.388
nhr-49 Protein NHR-49 0.386
unc-83 Protein UNC-83 0.381
F28B3.1 Protein F28B3.1 0.377
cul-2 Protein CUL-2 0.376
sax-3 Protein SAX-3 0.372
hbl-1 Protein HBL-1 0.371
gld-1 Protein GLD-1 0.370
C14C10.4 Protein C14C10.4 0.368
daf-14 Protein DAF-14 0.368
pgl-1 Protein PGL-1 0.366
div-1 Protein DIV-1 0.366
sna-2 Protein SNA-2 0.366
cks-1 Protein CKS-1 0.364
cdc-48.2 Protein CDC-48.2 0.362
prp-21 Protein PRP-21 0.360
ttx-1 Protein TTX-1 0.359
cku-80 Protein CKU-80 0.358
rps-15 Protein RPS-15 0.358
kars-1 Protein KARS-1 0.357
icp-1 Protein ICP-1 0.357
his-52 Protein HIS-52 0.357
nhr-46 Protein NHR-46 0.352
swsn-2.1 Protein SWSN-2.1 0.351
R02F2.7 Protein R02F2.7 0.349
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Danio rerio
Name Description Probability Func Analog Organism
notch1a notch homolog 1a 0.999
foxa2 forkhead box A2 0.994
bmp2b bone morphogenetic protein 2b 0.989
foxi1 forkhead box I1 0.987
tp53 tumor protein p53 0.977
fgf3 fibroblast growth factor 3 0.974
gli1 GLI-Kruppel family member 1 0.973
evx1 even-skipped homeobox 1 0.969
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.968
chd chordin 0.964
lhx1a LIM homeobox 1a 0.957
otx2 orthodenticle homolog 2 0.957
tfap2a transcription factor AP-2 alpha 0.956
pax8 paired box gene 8 0.952
cdh1 cadherin 1, epithelial 0.947
wnt5b wingless-type MMTV integration site family, member 5b 0.941
pcdh18b protocadherin 18b 0.933
tal1 T-cell acute lymphocytic leukemia 1 0.932
mespa mesoderm posterior a 0.926
nkx2.3 NK2 transcription factor related 3 0.923
foxa3 forkhead box A3 0.922
snai1b snail homolog 1b (Drosophila) 0.921
mapk1 mitogen-activated protein kinase 1 0.920
isl1 islet1 0.920
ptf1a pancreas specific transcription factor, 1a 0.919
tbx16 T-box gene 16 0.919
pax6a paired box gene 6a 0.919
lhx5 LIM homeobox 5 0.918
runx2b runt-related transcription factor 2b 0.916
ntla no tail a 0.909
dlx5a distal-less homeobox gene 5a 0.900
smad7 MAD, mothers against decapentaplegic homolog 7 (Drosophila) 0.896
shha sonic hedgehog a 0.894
fgf17 fibroblast growth factor 17 0.890
barx1 BarH-like homeobox 1 0.890
eomesa eomesodermin homolog a 0.888
otpb orthopedia homolog b 0.887
spry4 sprouty (Drosophila) homolog 4 0.887
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.886
foxg1a forkhead box G1a 0.884
pitx2 paired-like homeodomain transcription factor 2 0.884
sox9a SRY-box containing gene 9a 0.881
sesn1 sestrin 1 0.878
ndr2 nodal-related 2 0.878
fgfr3 fibroblast growth factor receptor 3 0.874
smo smoothened homolog (Drosophila) 0.873
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.870
hoxc4a homeo box C4a 0.869
oprd1b opioid receptor, delta 1b 0.869
hhex hematopoietically expressed homeobox 0.863
dkk1b dickkopf 1b 0.862
six4a sine oculis homeobox homolog 4a 0.859
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.857
hnf1ba HNF1 homeobox Ba 0.847
junb jun B proto-oncogene 0.840
fzd8b frizzled homolog 8b 0.831
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.831
sox32 SRY-box containing gene 32 0.828
nkx2.5 NK2 transcription factor related 5 0.826
lft1 lefty1 0.824
foxd3 forkhead box D3 0.824
otpa orthopedia homolog a 0.819
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.814
tyr tyrosinase 0.813
egr1 early growth response 1 0.812
gbx2 gastrulation brain homeo box 2 0.812
nkx3.2 NK3 homeobox 2 0.810
tll1 tolloid-like 1 0.806
six3b sine oculis homeobox homolog 3b 0.801
fgf8a fibroblast growth factor 8 a 0.793
ascl1a achaete-scute complex-like 1a (Drosophila) 0.790
rx3 retinal homeobox gene 3 0.789
ube2i ubiquitin-conjugating enzyme E2I 0.788
sox19a SRY-box containing gene 19a 0.787
fezf2 FEZ family zinc finger 2 0.782
notch1b notch homolog 1b 0.779
esco2 establishment of cohesion 1 homolog 2 0.777
rad21 RAD21 homolog (S. pombe) 0.776
raraa retinoic acid receptor, alpha a 0.774
sox21a SRY-box containing gene 21a 0.773
bmp4 bone morphogenetic protein 4 0.773
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.772
bmp2a bone morphogenetic protein 2a 0.771
fgfr4 fibroblast growth factor receptor 4 0.771
etv5b ets variant 5b 0.768
cav1 caveolin 1 0.767
cdx4 caudal type homeo box transcription factor 4 0.765
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.764
ccnd1 cyclin D1 0.764
twist1b twist1b 0.761
wnt11r wingless-type MMTV integration site family, member 11, related 0.758
sox1a SRY-box containing gene 1a 0.757
gbx1 gastrulation brain homeobox 1 0.756
klf4 Kruppel-like factor 4 0.754
eif3ha eukaryotic translation initiation factor 3, subunit H, a 0.752
wnt10a wingless-type MMTV integration site family, member 10a 0.752
hoxa9a homeo box A9a 0.750
six2a sine oculis-related homeobox 2a 0.741
rnf2 ring finger protein 2 0.740
cct5 chaperonin containing TCP1, subunit 5 (epsilon) 0.740
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism