The network for 'negative regulation of nematode larval development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of nematode larval development

Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.

Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.994
lin-36 Protein LIN-36 0.847
pry-1 Protein PRY-1 0.828
CELE_Y54G11A.11 Protein Y54G11A.11 0.785
mep-1 Protein MEP-1 0.776
pha-4 Protein PHA-4 0.749
gad-1 Protein GAD-1 0.742
hcp-3 Protein HCP-3 0.735
CELE_Y41E3.11 Protein Y41E3.11 0.727
ldb-1 Protein LDB-1 0.707
npp-4 Protein NPP-4 0.693
hlh-2 Protein HLH-2 0.679
lin-35 Protein LIN-35 0.637
hda-1 Protein HDA-1 0.632
dpy-22 Protein DPY-22 0.631
mix-1 Protein MIX-1 0.621
egl-27 Protein EGL-27 0.612
set-2 Protein SET-2 0.603
mat-3 Protein MAT-3 0.586
mog-4 Protein MOG-4 0.578
npp-7 Protein NPP-7 0.575
snr-3 Protein SNR-3 0.572
mab-5 Protein MAB-5 0.560
asd-1 Protein ASD-1 0.559
sur-2 Protein SUR-2 0.556
mig-5 Protein MIG-5 0.554
npp-5 Protein NPP-5 0.550
swsn-2.1 Protein SWSN-2.1 0.538
unc-73 Protein UNC-73 0.532
lst-3 Protein LST-3 0.527
athp-2 Protein ATHP-2 0.520
W04D2.6 Protein W04D2.6 0.513
hda-2 Protein HDA-2 0.511
hbl-1 Protein HBL-1 0.509
peb-1 Protein PEB-1 0.504
rsp-5 Protein RSP-5 0.498
F08B4.7 Protein F08B4.7 0.498
F35G12.4 Protein F35G12.4 0.489
capg-1 Protein CAPG-1 0.488
ubc-12 Protein UBC-12 0.486
mei-2 Protein MEI-2 0.480
unc-62 Protein UNC-62 0.476
hmp-1 Protein HMP-1 0.475
xnp-1 Protein XNP-1 0.457
mdt-8 Protein MDT-8 0.443
fasn-1 Protein FASN-1 0.443
nfya-1 Protein NFYA-1 0.440
spr-5 Protein SPR-5 0.436
snr-6 Protein SNR-6 0.435
abi-1 Protein ABI-1 0.433
sams-3 Protein SAMS-3 0.431
snr-2 Protein SNR-2 0.430
R11A8.7 Protein R11A8.7 0.428
emb-5 Protein EMB-5 0.423
lsy-2 Protein LSY-2 0.420
lin-15B Protein LIN-15B 0.413
ZC506.1 Protein ZC506.1 0.411
B0035.1 Protein B0035.1 0.407
met-2 Protein MET-2 0.405
vav-1 Protein VAV-1 0.405
rbd-1 Protein RBD-1 0.403
npp-1 Protein NPP-1 0.401
mut-16 Protein MUT-16 0.401
apx-1 Protein APX-1 0.400
F10E7.11 Protein F10E7.11 0.400
rnr-1 Protein RNR-1 0.396
sma-6 Protein SMA-6 0.394
dre-1 Protein DRE-1 0.394
vab-1 Protein VAB-1 0.393
psf-1 Protein PSF-1 0.391
unc-40 Protein UNC-40 0.390
F19B6.1 Protein F19B6.1 0.388
snr-4 Protein SNR-4 0.381
snrp-200 Protein SNRP-200 0.381
C02B10.4 Protein C02B10.4 0.380
lin-12 Protein LIN-12 0.373
T11G6.8 Protein T11G6.8 0.369
lin-13 Protein LIN-13 0.363
hmg-1.2 Protein HMG-1.2 0.360
cdtl-7 Protein CDTL-7 0.358
attf-2 Protein ATTF-2 0.347
tgt-1 Protein TGT-1 0.344
sel-12 Protein SEL-12 0.344
wnk-1 Protein WNK-1 0.344
gls-1 Protein GLS-1 0.343
eps-8 Protein EPS-8 0.340
ulp-2 Protein ULP-2 0.340
Y87G2A.1 Protein Y87G2A.1 0.340
ccr-4 Protein CCR-4 0.339
dnj-11 Protein DNJ-11 0.339
par-5 Protein PAR-5 0.338
nhr-25 Protein NHR-25 0.337
lin-25 Protein LIN-25 0.333
gex-2 Protein GEX-2 0.333
mom-2 Protein MOM-2 0.329
CELE_W03F9.2 Protein W03F9.2 0.327
ddb-1 Protein DDB-1 0.326
zyg-8 Protein ZYG-8 0.323
pbs-7 Protein PBS-7 0.317
egl-46 Protein EGL-46 0.310
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism