The network for 'regulation of cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.707
vab-3 Protein VAB-3 0.282
elt-6 Protein ELT-6 0.254
clk-2 Protein CLK-2 0.246
ceh-20 Protein CEH-20 0.241
pha-4 Protein PHA-4 0.229
nhr-67 Protein NHR-67 0.211
hlh-2 Protein HLH-2 0.207
mat-3 Protein MAT-3 0.180
unc-73 Protein UNC-73 0.178
lin-12 Protein LIN-12 0.178
sem-5 Protein SEM-5 0.176
par-5 Protein PAR-5 0.168
nhr-25 Protein NHR-25 0.146
lag-1 Protein LAG-1 0.144
rnp-6 Protein RNP-6 0.137
osm-6 Protein OSM-6 0.133
mex-5 Protein MEX-5 0.127
mel-11 Protein MEL-11 0.121
sel-8 Protein SEL-8 0.118
bar-1 Protein BAR-1 0.118
cam-1 Protein CAM-1 0.113
hgrs-1 Protein HGRS-1 0.112
CELE_C12D8.1 Protein C12D8.1 0.111
ect-2 Protein ECT-2 0.111
C34D10.2 Protein C34D10.2 0.108
zyg-1 Protein ZYG-1 0.108
hst-1 Protein HST-1 0.104
unc-62 Protein UNC-62 0.103
cey-1 Protein CEY-1 0.102
ceh-16 Protein CEH-16 0.100
imb-2 Protein IMB-2 0.100
wrm-1 Protein WRM-1 0.100
hlh-1 Protein HLH-1 0.099
igcm-3 Protein IGCM-3 0.099
mab-5 Protein MAB-5 0.099
sma-6 Protein SMA-6 0.099
sdz-28 Protein SDZ-28 0.098
attf-2 Protein ATTF-2 0.097
dcr-1 Protein DCR-1 0.095
mig-6 Protein MIG-6 0.093
mep-1 Protein MEP-1 0.092
gld-1 Protein GLD-1 0.091
lin-53 Protein LIN-53 0.091
inx-19 Protein INX-19 0.088
che-13 Protein CHE-13 0.088
akt-2 Protein AKT-2 0.088
lsy-22 Protein LSY-22 0.087
F21A10.2 Protein F21A10.2 0.086
M03C11.8 Protein M03C11.8 0.085
apn-1 Protein APN-1 0.085
C27A12.7 Protein C27A12.7 0.085
dnj-23 Protein DNJ-23 0.084
tra-1 Protein TRA-1 0.084
elt-2 Protein ELT-2 0.082
lmn-1 Protein LMN-1 0.081
C17H11.6 Protein C17H11.6 0.080
F59E12.11 Protein F59E12.11 0.080
unc-40 Protein UNC-40 0.080
hda-1 Protein HDA-1 0.079
gmeb-1 Protein GMEB-1 0.078
par-2 Protein PAR-2 0.077
daf-12 Protein DAF-12 0.077
egl-46 Protein EGL-46 0.075
trim-9 Protein TRIM-9 0.075
daf-3 Protein DAF-3 0.074
F42G9.1 Protein F42G9.1 0.073
lin-5 Protein LIN-5 0.073
cids-2 Protein CIDS-2 0.073
cnd-1 Protein CND-1 0.073
lin-37 Protein LIN-37 0.073
ced-9 Protein CED-9 0.073
mei-2 Protein MEI-2 0.072
npp-5 Protein NPP-5 0.071
CELE_C23G10.7 Protein C23G10.7 0.071
gei-18 Protein GEI-18 0.070
hpl-2 Protein HPL-2 0.070
brp-1 Protein BRP-1 0.069
sdn-1 Protein SDN-1 0.069
pry-1 Protein PRY-1 0.068
atg-2 Protein ATG-2 0.068
sax-7 Protein SAX-7 0.068
daf-1 Protein DAF-1 0.068
mpk-1 Protein MPK-1 0.067
sas-5 Protein SAS-5 0.067
dnc-2 Protein DNC-2 0.067
mel-28 Protein MEL-28 0.067
let-60 Protein LET-60 0.066
cki-1 Protein CKI-1 0.066
sax-3 Protein SAX-3 0.066
cwn-1 Protein CWN-1 0.065
osm-5 Protein OSM-5 0.065
dbr-1 Protein DBR-1 0.065
nhr-2 Protein NHR-2 0.064
CELE_C25A1.4 Protein C25A1.4 0.064
F28C6.4 Protein F28C6.4 0.064
sec-31 Protein SEC-31 0.064
T05G5.1 Protein T05G5.1 0.064
pis-1 Protein PIS-1 0.063
osm-3 Protein OSM-3 0.063
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Danio rerio
Name Description Probability Func Analog Organism
bmp2b bone morphogenetic protein 2b 0.966
tp53 tumor protein p53 0.956
tbx1 T-box 1 0.890
boc brother of CDO 0.875
shha sonic hedgehog a 0.821
wnt5b wingless-type MMTV integration site family, member 5b 0.803
ndr2 nodal-related 2 0.777
dld deltaD 0.657
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.650
dag1 dystroglycan 1 0.608
foxi1 forkhead box I1 0.601
fgf8a fibroblast growth factor 8 a 0.553
robo3 roundabout homolog 3 0.526
dlx5a distal-less homeobox gene 5a 0.521
foxg1a forkhead box G1a 0.461
rarga retinoic acid receptor gamma a 0.460
kdrl kinase insert domain receptor like 0.455
dzip1 DAZ interacting protein 1 0.454
bmp2a bone morphogenetic protein 2a 0.419
smo smoothened homolog (Drosophila) 0.403
fgf3 fibroblast growth factor 3 0.402
cdc25 cell division cycle 25 homolog 0.392
tbx16 T-box gene 16 0.391
efnb2a ephrin B2a 0.385
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.370
tp63 tumor protein p63 0.351
igf1 insulin-like growth factor 1 0.347
chd chordin 0.343
eomesa eomesodermin homolog a 0.343
lamc1 laminin, gamma 1 0.340
mib mind bomb 0.338
cav1 caveolin 1 0.330
dharma dharma 0.330
hand2 heart and neural crest derivatives expressed transcript 2 0.317
kita kit receptor a 0.299
lhx1a LIM homeobox 1a 0.286
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.286
sox19a SRY-box containing gene 19a 0.278
plcg1 phospholipase C, gamma 1 0.276
wnt4a wingless-type MMTV integration site family, member 4a 0.262
mab21l2 mab-21-like 2 0.261
acvr1l activin A receptor, type I like 0.254
ran ras-related nuclear protein 0.253
wnt11r wingless-type MMTV integration site family, member 11, related 0.252
myca myelocytomatosis oncogene a 0.242
tgfb1a transforming growth factor, beta 1a 0.238
dusp6 dual specificity phosphatase 6 0.238
znf703 zinc finger protein 703 0.224
hoxa2b homeo box A2b 0.221
nkx2.3 NK2 transcription factor related 3 0.215
igf2b insulin-like growth factor 2b 0.207
notch1a notch homolog 1a 0.206
hmx4 H6 family homeobox 4 0.205
cxcr4a chemokine (C-X-C motif) receptor 4a 0.204
fgfr3 fibroblast growth factor receptor 3 0.199
spns2 spinster homolog 2 (Drosophila) 0.198
twist3 twist3 0.196
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.195
cdh1 cadherin 1, epithelial 0.194
her7 hairy and enhancer of split related-7 0.186
pcna proliferating cell nuclear antigen 0.184
emx3 empty spiracles homeobox 3 0.184
aplnra apelin receptor a 0.182
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.180
ihha Indian hedgehog homolog a 0.180
krt4 keratin 4 0.176
eya1 eyes absent homolog 1 0.170
sox3 SRY-box containing gene 3 0.168
epha4b eph receptor A4b 0.168
meis3 myeloid ecotropic viral integration site 3 0.164
fn1 fibronectin 1 0.159
ptgs2a prostaglandin-endoperoxide synthase 2a 0.153
etv2 ets variant gene 2 0.152
gata6 GATA-binding protein 6 0.151
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.147
ascl1a achaete-scute complex-like 1a (Drosophila) 0.146
dhrs3a dehydrogenase/reductase (SDR family) member 3a 0.145
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.143
ocrl oculocerebrorenal syndrome of Lowe 0.143
pax2a paired box gene 2a 0.142
hoxd4a homeo box D4a 0.141
flt4 fms-related tyrosine kinase 4 0.139
grem2 gremlin 2, cysteine knot superfamily 0.138
mitfa microphthalmia-associated transcription factor a 0.138
ctsk cathepsin K 0.137
gata4 GATA-binding protein 4 0.136
otpb orthopedia homolog b 0.136
mef2ca myocyte enhancer factor 2ca 0.134
pitx3 paired-like homeodomain transcription factor 3 0.134
osr1 odd-skipped related 1 (Drosophila) 0.130
igfbp3 insulin-like growth factor binding protein 3 0.130
nkx2.5 NK2 transcription factor related 5 0.129
bmp4 bone morphogenetic protein 4 0.127
smad7 MAD, mothers against decapentaplegic homolog 7 (Drosophila) 0.126
nkx2.2a NK2 transcription factor related 2a 0.126
pcdh18b protocadherin 18b 0.125
axin2 axin 2 (conductin, axil) 0.125
nkx2.1a NK2 homeobox 1a 0.125
tgfb3 transforming growth factor, beta 3 0.125
klf4a Kruppel-like transcription factor 4a 0.124
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Drosophila melanogaster
Name Description Probability Func Analog Organism
brm brahma 0.998
InR Insulin-like receptor 0.997
nej nejire 0.993
Akt1 CG4006 gene product from transcript CG4006-RA 0.990
N Notch 0.985
hep hemipterous 0.979
Moe Moesin 0.972
ftz-f1 ftz transcription factor 1 0.970
yki yorkie 0.960
ed echinoid 0.956
rl rolled 0.955
Fmr1 CG6203 gene product from transcript CG6203-RC 0.955
dm diminutive 0.952
Dad Daughters against dpp 0.941
Ubx Ultrabithorax 0.940
ci cubitus interruptus 0.931
shi shibire 0.928
gro groucho 0.910
stck steamer duck 0.904
da daughterless 0.904
hpo hippo 0.884
babo baboon 0.872
wts warts 0.870
Rab5 Rab-protein 5 0.845
foxo forkhead box, sub-group O 0.843
shn schnurri 0.836
Snr1 Snf5-related 1 0.829
brk brinker 0.827
ft fat 0.807
Rel Relish 0.806
EcR Ecdysone receptor 0.790
bowl brother of odd with entrails limited 0.787
trx trithorax 0.784
hth homothorax 0.779
Mad Mothers against dpp 0.776
kay kayak 0.771
wg wingless 0.767
l(2)gl lethal (2) giant larvae 0.765
pnr pannier 0.725
ush u-shaped 0.716
Pk61C Protein kinase 61C 0.714
ecd ecdysoneless 0.709
so sine oculis 0.708
pnt pointed 0.704
osa CG7467 gene product from transcript CG7467-RD 0.690
ago archipelago 0.681
E(spl) Enhancer of split 0.672
ato atonal 0.666
bel belle 0.659
kibra kibra ortholog 0.646
hipk homeodomain interacting protein kinase 0.642
fz frizzled 0.641
run runt 0.638
S6k RPS6-p70-protein kinase 0.635
Snoo Sno oncogene 0.632
Antp Antennapedia 0.619
ttk tramtrack 0.616
shot short stop 0.615
abd-A abdominal A 0.615
mxc multi sex combs 0.612
smt3 CG4494 gene product from transcript CG4494-RA 0.602
slp1 sloppy paired 1 0.597
put punt 0.595
Pten CG5671 gene product from transcript CG5671-RB 0.594
pan pangolin 0.594
Stat92E Signal-transducer and activator of transcription protein at 92E 0.593
Nrg Neuroglian 0.589
Abl Abl tyrosine kinase 0.584
Src42A Src oncogene at 42A 0.567
Fcp1 CG12252 gene product from transcript CG12252-RA 0.562
WASp CG1520 gene product from transcript CG1520-RA 0.562
tgo tango 0.560
smo smoothened 0.559
dsh dishevelled 0.558
frc fringe connection 0.554
Mhc Myosin heavy chain 0.546
os outstretched 0.545
gsb gooseberry 0.543
stg string 0.538
dally division abnormally delayed 0.538
Bap55 Brahma associated protein 55kD 0.537
sli slit 0.526
LamC Lamin C 0.513
bif bifocal 0.509
dac dachshund 0.507
awd abnormal wing discs 0.506
Rho1 CG8416 gene product from transcript CG8416-RB 0.505
e(y)3 enhancer of yellow 3 0.498
tsh teashirt 0.492
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.474
robo3 CG5423 gene product from transcript CG5423-RA 0.460
Ras85D Ras oncogene at 85D 0.445
tefu telomere fusion 0.444
Atg1 Autophagy-specific gene 1 0.442
sina seven in absentia 0.439
scrib scribbled 0.439
Mrtf Myocardin-related transcription factor 0.431
L Lobe 0.429
slou slouch 0.415
asp abnormal spindle 0.414
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Anxa2 annexin A2 0.860
Esr1 estrogen receptor 1 0.846
S100a10 S100 calcium binding protein A10 0.832
Ddr1 discoidin domain receptor tyrosine kinase 1 0.820
Anxa5 annexin A5 0.816
Cga glycoprotein hormones, alpha polypeptide 0.807
Tgfbr2 transforming growth factor, beta receptor II 0.776
Flt1 FMS-related tyrosine kinase 1 0.769
Irs1 insulin receptor substrate 1 0.765
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.756
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.755
Gja5 gap junction protein, alpha 5 0.754
Gpx3 glutathione peroxidase 3 0.740
Lgals3 lectin, galactoside-binding, soluble, 3 0.731
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B 0.720
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.709
Foxs1 forkhead box S1 0.691
Mrgprf MAS-related GPR, member F 0.690
Efnb1 ephrin B1 0.688
Jak2 Janus kinase 2 0.686
Cd4 Cd4 molecule 0.682
Utrn utrophin 0.678
Cd44 Cd44 molecule 0.672
Smad3 SMAD family member 3 0.659
Arpc1b actin related protein 2/3 complex, subunit 1B 0.656
Cav1 caveolin 1, caveolae protein 0.654
Lif leukemia inhibitory factor 0.631
Apoa4 apolipoprotein A-IV 0.631
RT1-Ba RT1 class II, locus Ba 0.623
Stat6 signal transducer and activator of transcription 6 0.622
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.616
Dchs1 dachsous 1 (Drosophila) 0.614
Klf6 Kruppel-like factor 6 0.613
Akr1c18 aldo-keto reductase family 1, member C18 0.606
Pecam1 platelet/endothelial cell adhesion molecule 1 0.606
Nos3 nitric oxide synthase 3, endothelial cell 0.605
Ptafr platelet-activating factor receptor 0.604
Anxa1 annexin A1 0.597
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.592
S100a8 S100 calcium binding protein A8 0.584
Ccl4 chemokine (C-C motif) ligand 4 0.583
Lgals1 lectin, galactoside-binding, soluble, 1 0.581
Syt8 synaptotagmin VIII 0.581
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.576
Trhr2 thyrotropin releasing hormone receptor 2 0.571
Fgfr2 fibroblast growth factor receptor 2 0.571
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.569
Cxcl2 chemokine (C-X-C motif) ligand 2 0.567
Crhbp corticotropin releasing hormone binding protein 0.565
Foxd1 forkhead box D1 0.554
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.550
Foxa3 forkhead box A3 0.545
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.541
Cmklr1 chemokine-like receptor 1 0.537
Asgr2 asialoglycoprotein receptor 2 0.535
Pla2g2c phospholipase A2, group IIC 0.535
Cxcr5 chemokine (C-X-C motif) receptor 5 0.535
Galr3 galanin receptor 3 0.533
Vom2r27 vomeronasal 2 receptor, 27 0.531
Sstr5 somatostatin receptor 5 0.528
Nrg1 neuregulin 1 0.526
Ccl11 chemokine (C-C motif) ligand 11 0.525
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.521
Il8rb interleukin 8 receptor, beta 0.521
Gjb3 gap junction protein, beta 3 0.518
Ncan neurocan 0.512
Kcns1 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 0.502
RT1-Da RT1 class II, locus Da 0.501
Bcl2 B-cell CLL/lymphoma 2 0.500
Cd40lg CD40 ligand 0.493
Cntn3 contactin 3 (plasmacytoma associated) 0.487
Cd63 Cd63 molecule 0.486
Gpr1 G protein-coupled receptor 1 0.481
Oxtr oxytocin receptor 0.479
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.475
Fgf18 fibroblast growth factor 18 0.470
Oprm1 opioid receptor, mu 1 0.468
Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 0.468
Glp1r glucagon-like peptide 1 receptor 0.467
Nefm neurofilament, medium polypeptide 0.457
Hmox1 heme oxygenase (decycling) 1 0.456
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.450
Bmp6 bone morphogenetic protein 6 0.447
Galr2 galanin receptor 2 0.447
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.447
Mmp9 matrix metallopeptidase 9 0.445
Tas2r107 taste receptor, type 2, member 107 0.444
Clps colipase, pancreatic 0.443
Vcan versican 0.440
Egr1 early growth response 1 0.439
Tpc1808 tropic 1808 0.437
Chrne cholinergic receptor, nicotinic, epsilon 0.436
Olr287 olfactory receptor 287 0.436
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.433
Atxn1 ataxin 1 0.432
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.431
Inpp5d inositol polyphosphate-5-phosphatase D 0.430
Creb1 cAMP responsive element binding protein 1 0.430
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.430
Gper G protein-coupled estrogen receptor 1 0.423
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism