The network for 'apoptotic cell clearance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

apoptotic cell clearance

The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
gei-18 Protein GEI-18 0.383
atn-1 Protein ATN-1 0.179
sem-5 Protein SEM-5 0.178
ptr-11 Protein PTR-11 0.161
rab-5 Protein RAB-5 0.135
sas-4 Protein SAS-4 0.134
T19A5.3 Protein T19A5.3 0.119
rme-8 Protein RME-8 0.117
sptl-3 Protein SPTL-3 0.115
rgl-1 Protein RGL-1 0.114
snx-1 Protein SNX-1 0.108
C06E8.5 Protein C06E8.5 0.106
hpo-22 Protein HPO-22 0.101
ptr-6 Protein PTR-6 0.098
lat-1 Protein LAT-1 0.097
R10E11.6 Protein R10E11.6 0.097
unc-73 Protein UNC-73 0.095
ced-3 Protein CED-3 0.092
mex-1 Protein MEX-1 0.092
C52E12.4 Protein C52E12.4 0.092
scpl-2 Protein SCPL-2 0.088
math-3 Protein MATH-3 0.086
hpo-28 Protein HPO-28 0.086
pat-2 Protein PAT-2 0.086
upb-1 Protein UPB-1 0.085
K10C8.3 Protein K10C8.3 0.082
cka-1 Protein CKA-1 0.082
dyn-1 Protein DYN-1 0.081
ubr-1 Protein UBR-1 0.078
slo-1 Protein SLO-1 0.075
skn-1 Protein SKN-1 0.075
taf-1 Protein TAF-1 0.074
F08B12.1 Protein F08B12.1 0.074
swd-2.2 Protein SWD-2.2 0.073
CELE_C16C10.2 Protein C16C10.2 0.072
C29H12.2 Protein C29H12.2 0.072
Y75B7AR.1 Protein Y75B7AR.1 0.071
kin-2 Protein KIN-2 0.070
praf-3 Protein PRAF-3 0.069
C16A3.6 Protein C16A3.6 0.068
vps-37 Protein VPS-37 0.067
npp-7 Protein NPP-7 0.066
arx-2 Protein ARX-2 0.066
acl-14 Protein ACL-14 0.065
F59A3.4 Protein F59A3.4 0.064
CELE_Y39B6A.1 Protein Y39B6A.1 0.064
egl-27 Protein EGL-27 0.064
paqr-3 Protein PAQR-3 0.063
pst-1 Protein PST-1 0.061
F09B12.3 Protein F09B12.3 0.061
zyg-8 Protein ZYG-8 0.060
C14H10.2 Protein C14H10.2 0.059
K02G10.5 Protein K02G10.5 0.059
ZC247.2 Protein ZC247.2 0.059
unc-50 Protein UNC-50 0.059
plc-3 Protein PLC-3 0.058
K04G2.6 Protein K04G2.6 0.058
nra-3 Protein NRA-3 0.058
pld-1 Protein PLD-1 0.058
nhx-9 Protein NHX-9 0.058
pry-1 Protein PRY-1 0.058
F45D3.2 Protein F45D3.2 0.057
ced-6 Protein CED-6 0.057
nhr-3 Protein NHR-3 0.057
Y25C1A.5 Protein Y25C1A.5 0.057
chc-1 Protein CHC-1 0.057
acs-20 Protein ACS-20 0.057
ZC21.3 Protein ZC21.3 0.057
F13D12.3 Protein F13D12.3 0.056
pdhb-1 Protein PDHB-1 0.056
vab-3 Protein VAB-3 0.056
ced-9 Protein CED-9 0.056
snap-29 Protein SNAP-29 0.056
Y106G6A.1 Protein Y106G6A.1 0.056
pat-3 Protein PAT-3 0.055
epg-8 Protein EPG-8 0.055
trim-9 Protein TRIM-9 0.055
unc-43 Protein UNC-43 0.055
cam-1 Protein CAM-1 0.055
mam-3 Protein MAM-3 0.054
T10E9.1 Protein T10E9.1 0.054
avr-14 Protein AVR-14 0.054
tpxl-1 Protein TPXL-1 0.054
ran-5 Protein RAN-5 0.054
ced-10 Protein CED-10 0.054
mig-2 Protein MIG-2 0.054
unc-62 Protein UNC-62 0.054
C33A11.1 Protein C33A11.1 0.053
sar-1 Protein SAR-1 0.053
F13H6.1 Protein F13H6.1 0.053
ptr-14 Protein PTR-14 0.053
atx-2 Protein ATX-2 0.053
C14C11.7 Protein C14C11.7 0.053
riok-3 Protein RIOK-3 0.053
par-1 Protein PAR-1 0.052
M02B7.2 Protein M02B7.2 0.052
zhit-1 Protein ZHIT-1 0.052
C32D5.11 Protein C32D5.11 0.052
egl-30 Protein EGL-30 0.051
F13B12.1 Protein F13B12.1 0.051
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
bsk basket 0.671
Fhos CG42610 gene product from transcript CG42610-RC 0.646
mbc myoblast city 0.622
Rab5 Rab-protein 5 0.618
Pvr PDGF- and VEGF-receptor related 0.611
Atg1 Autophagy-specific gene 1 0.604
Rho1 CG8416 gene product from transcript CG8416-RB 0.597
Rac1 CG2248 gene product from transcript CG2248-RA 0.476
Rac2 CG8556 gene product from transcript CG8556-RA 0.450
srp serpent 0.435
scb scab 0.417
Cdc42 CG12530 gene product from transcript CG12530-RA 0.336
Rab7 Rab-protein 7 0.238
beta-Spec beta Spectrin 0.232
mts microtubule star 0.227
drpr draper 0.225
retn retained 0.210
milt milton 0.205
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.188
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.171
repo reversed polarity 0.143
Dlic Dynein light intermediate chain 0.143
msn misshapen 0.140
Pak PAK-kinase 0.138
prtp pretaporter 0.132
imd immune deficiency 0.129
chic chickadee 0.119
sdt stardust 0.111
ced-6 CG11804 gene product from transcript CG11804-RC 0.108
plexB plexin B 0.108
Rab11 Rab-protein 11 0.090
Eb1 CG3265 gene product from transcript CG3265-RF 0.088
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.082
Arf79F ADP ribosylation factor 79F 0.082
CG10743 CG10743 gene product from transcript CG10743-RB 0.081
her hermaphrodite 0.074
Vps16A Vacuolar protein sorting 16A 0.062
Pkn Protein kinase related to protein kinase N 0.062
mew multiple edematous wings 0.060
Rala Ras-related protein 0.059
Moe Moesin 0.056
fkh fork head 0.055
kst karst 0.055
Src42A Src oncogene at 42A 0.053
Tak1 TGF-beta activated kinase 1 0.053
Orc5 Origin recognition complex subunit 5 0.052
Gef26 CG9491 gene product from transcript CG9491-RB 0.052
Akt1 CG4006 gene product from transcript CG4006-RA 0.049
spz spatzle 0.048
stumps CG31317 gene product from transcript CG31317-RC 0.047
Grip Glutamate receptor binding protein 0.045
inaD inactivation no afterpotential D 0.043
RhoL rho-like 0.041
nimC4 nimrod C4 0.040
Sop2 Suppressor of profilin 2 0.036
Letm1 CG4589 gene product from transcript CG4589-RB 0.036
zip zipper 0.035
kel kelch 0.034
zfh1 Zn finger homeodomain 1 0.034
Galpha49B G protein alpha49B 0.032
pan pangolin 0.032
CG16718 CG16718 gene product from transcript CG16718-RA 0.030
Pcaf CG4107 gene product from transcript CG4107-RA 0.029
Dok Downstream of kinase 0.028
Pink1 PTEN-induced putative kinase 1 0.028
Mef2 Myocyte enhancer factor 2 0.027
Stim Stromal interaction molecule 0.026
sr stripe 0.026
CG3563 CG3563 gene product from transcript CG3563-RA 0.025
ena enabled 0.024
crn crooked neck 0.024
DAAM Dishevelled Associated Activator of Morphogenesis 0.024
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.024
r2d2 CG7138 gene product from transcript CG7138-RB 0.024
Pi3K68D Phosphotidylinositol 3 kinase 68D 0.023
CG1129 CG1129 gene product from transcript CG1129-RC 0.023
CG9801 CG9801 gene product from transcript CG9801-RC 0.023
insc inscuteable 0.023
Mmp1 Matrix metalloproteinase 1 0.022
myoglianin CG1838 gene product from transcript CG1838-RD 0.022
vav CG7893 gene product from transcript CG7893-RB 0.022
l(1)G0020 lethal (1) G0020 0.022
MED4 Mediator complex subunit 4 0.021
Hs6st Heparan sulfate 6-O-sulfotransferase 0.021
Ost48 Oligosaccharyltransferase 48kD subunit 0.021
Vrp1 Verprolin 1 0.021
Pak3 CG14895 gene product from transcript CG14895-RA 0.021
egr eiger 0.021
MED15 Mediator complex subunit 15 0.020
CG4680 CG4680 gene product from transcript CG4680-RA 0.020
grk gurken 0.019
CG4306 CG4306 gene product from transcript CG4306-RA 0.019
twi twist 0.019
Jra Jun-related antigen 0.019
Ppcs Phosphopantothenoylcysteine synthetase 0.019
Wnt5 Wnt oncogene analog 5 0.019
chb chromosome bows 0.019
wb wing blister 0.019
Dcp-1 Death caspase-1 0.018
CG1468 CG1468 gene product from transcript CG1468-RA 0.018
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Homo sapiens
Name Description Probability Func Analog Organism
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.992
FN1 fibronectin 1 0.978
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.722
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.657
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.626
SH3KBP1 SH3-domain kinase binding protein 1 0.538
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.491
EGFR epidermal growth factor receptor 0.405
RXRA retinoid X receptor, alpha 0.313
ANXA1 annexin A1 0.312
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.305
PXN paxillin 0.291
SNX6 sorting nexin 6 0.281
FGF1 fibroblast growth factor 1 (acidic) 0.277
CFLAR CASP8 and FADD-like apoptosis regulator 0.234
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.217
FASLG Fas ligand (TNF superfamily, member 6) 0.187
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.186
GRB2 growth factor receptor-bound protein 2 0.156
AXL AXL receptor tyrosine kinase 0.150
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.149
MAP2K4 mitogen-activated protein kinase kinase 4 0.142
ATF2 activating transcription factor 2 0.138
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.122
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.121
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.117
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.109
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.097
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.095
MAPK8 mitogen-activated protein kinase 8 0.091
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.090
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.083
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 0.082
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.081
ATG13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.079
LAT linker for activation of T cells 0.072
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.071
GAS6 growth arrest-specific 6 0.069
JUN jun proto-oncogene 0.068
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.066
VIM vimentin 0.063
ABI1 abl-interactor 1 0.056
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.055
RAB1A RAB1A, member RAS oncogene family 0.052
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.050
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.048
FGFR1 fibroblast growth factor receptor 1 0.044
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.044
POLA2 polymerase (DNA directed), alpha 2 (70kD subunit) 0.042
ADAM19 ADAM metallopeptidase domain 19 0.040
PDCD6IP programmed cell death 6 interacting protein 0.039
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.038
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.037
FGFR2 fibroblast growth factor receptor 2 0.036
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.036
RHOA ras homolog gene family, member A 0.036
SLMAP sarcolemma associated protein 0.034
RARA retinoic acid receptor, alpha 0.033
RAB7A RAB7A, member RAS oncogene family 0.033
MED25 mediator complex subunit 25 0.032
DYNLT3 dynein, light chain, Tctex-type 3 0.031
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.031
ITGB5 integrin, beta 5 0.030
APOE apolipoprotein E 0.030
ANXA2 annexin A2 0.030
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.030
FNBP1 formin binding protein 1 0.029
SESN2 sestrin 2 0.029
PICALM phosphatidylinositol binding clathrin assembly protein 0.029
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.028
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.027
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.027
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.027
NXF1 nuclear RNA export factor 1 0.026
IQGAP1 IQ motif containing GTPase activating protein 1 0.026
SOS1 son of sevenless homolog 1 (Drosophila) 0.025
KIF5B kinesin family member 5B 0.024
CTGF connective tissue growth factor 0.024
NCKAP1 NCK-associated protein 1 0.023
RB1CC1 RB1-inducible coiled-coil 1 0.023
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.023
FAS Fas (TNF receptor superfamily, member 6) 0.022
APP amyloid beta (A4) precursor protein 0.022
EPS8 epidermal growth factor receptor pathway substrate 8 0.022
NAV1 neuron navigator 1 0.021
WASL Wiskott-Aldrich syndrome-like 0.021
FADD Fas (TNFRSF6)-associated via death domain 0.021
BCOR BCL6 corepressor 0.021
MAPK6 mitogen-activated protein kinase 6 0.020
FYN FYN oncogene related to SRC, FGR, YES 0.020
ADAM15 ADAM metallopeptidase domain 15 0.020
SETDB1 SET domain, bifurcated 1 0.018
PDHX pyruvate dehydrogenase complex, component X 0.018
SH3GL2 SH3-domain GRB2-like 2 0.018
NCOA1 nuclear receptor coactivator 1 0.018
CD247 CD247 molecule 0.018
ARRB1 arrestin, beta 1 0.017
NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 0.017
ADAM9 ADAM metallopeptidase domain 9 0.017
VCL vinculin 0.017
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Mus musculus
Name Description Probability Func Analog Organism
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.785
Ctnnb1 catenin (cadherin associated protein), beta 1 0.649
Axl AXL receptor tyrosine kinase 0.636
Lyz2 lysozyme 2 0.522
Apoe apolipoprotein E 0.501
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.398
Pten phosphatase and tensin homolog 0.334
Gsk3b glycogen synthase kinase 3 beta 0.318
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.287
Lrp1 low density lipoprotein receptor-related protein 1 0.286
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.212
Tlr4 toll-like receptor 4 0.167
Cxcr4 chemokine (C-X-C motif) receptor 4 0.143
Itgb2 integrin beta 2 0.141
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.140
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.107
Cd44 CD44 antigen 0.103
Tyro3 TYRO3 protein tyrosine kinase 3 0.100
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.098
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.098
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.091
Axin1 axin 1 0.088
Npc1 Niemann Pick type C1 0.088
Il6st interleukin 6 signal transducer 0.079
Ptk2 PTK2 protein tyrosine kinase 2 0.077
Rbl2 retinoblastoma-like 2 0.072
Gab1 growth factor receptor bound protein 2-associated protein 1 0.067
Rxra retinoid X receptor alpha 0.066
Cav1 caveolin 1, caveolae protein 0.065
Mapk14 mitogen-activated protein kinase 14 0.063
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.062
Dysf dysferlin 0.062
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.057
Tbx3 T-box 3 0.049
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.047
Mmp9 matrix metallopeptidase 9 0.044
Osmr oncostatin M receptor 0.044
Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 0.044
Lgals1 lectin, galactose binding, soluble 1 0.043
Htt huntingtin 0.043
Bmpr1a bone morphogenetic protein receptor, type 1A 0.042
Lgals3 lectin, galactose binding, soluble 3 0.042
Selp selectin, platelet 0.041
Itgb3 integrin beta 3 0.040
Mapk9 mitogen-activated protein kinase 9 0.040
Twsg1 twisted gastrulation homolog 1 (Drosophila) 0.040
Lrp6 low density lipoprotein receptor-related protein 6 0.039
Il1b interleukin 1 beta 0.038
Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 0.038
Il1r1 interleukin 1 receptor, type I 0.036
Apc adenomatosis polyposis coli 0.035
Nf2 neurofibromatosis 2 0.035
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.035
Tmem38b transmembrane protein 38B 0.035
Il10ra interleukin 10 receptor, alpha 0.032
Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 0.032
Fgfr1 fibroblast growth factor receptor 1 0.032
Smad3 MAD homolog 3 (Drosophila) 0.032
Ltb lymphotoxin B 0.031
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.031
Ccr1 chemokine (C-C motif) receptor 1 0.030
Ccr2 chemokine (C-C motif) receptor 2 0.029
S100a6 S100 calcium binding protein A6 (calcyclin) 0.029
Dck deoxycytidine kinase 0.029
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.029
Cd9 CD9 antigen 0.029
Cxcl13 chemokine (C-X-C motif) ligand 13 0.028
C3 complement component 3 0.028
Trp63 transformation related protein 63 0.028
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.027
Pacsin1 protein kinase C and casein kinase substrate in neurons 1 0.027
Plxnd1 plexin D1 0.027
Vangl2 vang-like 2 (van gogh, Drosophila) 0.026
Inpp5d inositol polyphosphate-5-phosphatase D 0.025
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.024
Mdm2 transformed mouse 3T3 cell double minute 2 0.024
Igf1 insulin-like growth factor 1 0.024
Mertk c-mer proto-oncogene tyrosine kinase 0.024
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.024
Cd28 CD28 antigen 0.024
Rdh8 retinol dehydrogenase 8 0.024
Atg13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.023
Csf1 colony stimulating factor 1 (macrophage) 0.023
Dlg4 discs, large homolog 4 (Drosophila) 0.023
Klf5 Kruppel-like factor 5 0.023
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.023
Vcl vinculin 0.023
Tlr2 toll-like receptor 2 0.022
Pthlh parathyroid hormone-like peptide 0.022
Ldlr low density lipoprotein receptor 0.022
Arhgap1 Rho GTPase activating protein 1 0.022
Litaf LPS-induced TN factor 0.022
Stim2 stromal interaction molecule 2 0.021
Pou2af1 POU domain, class 2, associating factor 1 0.021
S100a11 S100 calcium binding protein A11 (calgizzarin) 0.021
Ednra endothelin receptor type A 0.021
Mvp major vault protein 0.021
Irf5 interferon regulatory factor 5 0.021
Nde1 nuclear distribution gene E homolog 1 (A nidulans) 0.021
Icam1 intercellular adhesion molecule 1 0.020
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism