The network for 'endoplasmic reticulum unfolded protein response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

endoplasmic reticulum unfolded protein response

The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
abu-15 Protein ABU-15 0.994
abu-1 Protein ABU-1 0.989
tag-320 Protein TAG-320 0.971
abu-11 Protein ABU-11 0.965
hsp-16.2 Protein HSP-16.2 0.960
hsp-70 Protein HSP-70 0.917
hsp-16.1 Protein HSP-16.1 0.906
abu-8 Protein ABU-8 0.860
hsp-16.41 Protein HSP-16.41 0.835
F44E5.4 Protein F44E5.4 0.806
dnj-7 Protein DNJ-7 0.791
pqn-54 Protein PQN-54 0.777
dct-18 Protein DCT-18 0.717
abu-6 Protein ABU-6 0.712
CELE_T05E11.3 Protein T05E11.3 0.700
hsp-16.48 Protein HSP-16.48 0.689
hsp-3 Protein HSP-3 0.627
abu-10 Protein ABU-10 0.619
F13E6.5 Protein F13E6.5 0.607
pqn-74 Protein PQN-74 0.576
Y47D3B.6 Protein Y47D3B.6 0.497
sec-22 Protein SEC-22 0.473
F41E6.11 Protein F41E6.11 0.467
CELE_T06E4.8 Protein T06E4.8 0.436
abu-9 Protein ABU-9 0.397
abu-14 Protein ABU-14 0.378
hsp-4 Protein HSP-4 0.353
pqn-63 Protein PQN-63 0.350
pdi-3 Protein PDI-3 0.305
hsp-17 Protein HSP-17 0.301
erv-46 Protein ERV-46 0.295
pdi-2 Protein PDI-2 0.293
Y94H6A.7 Protein Y94H6A.7 0.290
prp-8 Protein PRP-8 0.290
trap-2 Protein TRAP-2 0.274
CELE_T06E4.9 Protein T06E4.9 0.268
myo-1 Protein MYO-1 0.264
CELE_F20G2.2 Protein F20G2.2 0.264
CELE_F29C12.4 Protein F29C12.4 0.261
dsc-4 Protein DSC-4 0.251
nra-4 Protein NRA-4 0.247
ifd-1 Protein IFD-1 0.226
lys-1 Protein LYS-1 0.215
T25E4.1 Protein T25E4.1 0.215
gst-1 Protein GST-1 0.201
ZK686.3 Protein ZK686.3 0.177
ser-3 Protein SER-3 0.173
stt-3 Protein STT-3 0.171
R03C1.1 Protein R03C1.1 0.165
ostb-1 Protein OSTB-1 0.158
C29F3.7 Protein C29F3.7 0.153
pqn-71 Protein PQN-71 0.146
C53C9.2 Protein C53C9.2 0.145
T14G8.3 Protein T14G8.3 0.144
ZC506.1 Protein ZC506.1 0.140
mboa-3 Protein MBOA-3 0.139
CELE_ZK550.3 Protein ZK550.3 0.133
F53B3.3 Protein F53B3.3 0.132
sgt-1 Protein SGT-1 0.130
ckb-2 Protein CKB-2 0.122
hpo-34 Protein HPO-34 0.120
M02G9.1 Protein M02G9.1 0.118
crt-1 Protein CRT-1 0.114
Y19D2B.1 Protein Y19D2B.1 0.110
tufm-1 Protein TUFM-1 0.108
cdd-1 Protein CDD-1 0.108
eef-1A.1 Protein EEF-1A.1 0.106
hsp-1 Protein HSP-1 0.105
clc-3 Protein CLC-3 0.105
D2096.6 Protein D2096.6 0.103
cut-4 Protein CUT-4 0.102
rpia-1 Protein RPIA-1 0.099
gdi-1 Protein GDI-1 0.097
hsp-16.11 Protein HSP-16.11 0.097
paa-1 Protein PAA-1 0.097
glr-5 Protein GLR-5 0.096
H43E16.1 Protein H43E16.1 0.095
fic-1 Protein FIC-1 0.092
dnpp-1 Protein DNPP-1 0.092
dop-3 Protein DOP-3 0.091
pqn-57 Protein PQN-57 0.090
smp-1 Protein SMP-1 0.086
C30F12.3 Protein C30F12.3 0.086
CELE_Y39B6A.1 Protein Y39B6A.1 0.084
suca-1 Protein SUCA-1 0.084
glod-4 Protein GLOD-4 0.083
nkat-3 Protein NKAT-3 0.081
lec-6 Protein LEC-6 0.081
daf-1 Protein DAF-1 0.078
ubq-1 Protein UBQ-1 0.077
T10B10.3 Protein T10B10.3 0.074
CELE_F38E1.9 Protein F38E1.9 0.073
lron-10 Protein LRON-10 0.072
T08B1.1 Protein T08B1.1 0.072
F47G9.1 Protein F47G9.1 0.071
gale-1 Protein GALE-1 0.070
dnc-2 Protein DNC-2 0.069
ile-2 Protein ILE-2 0.068
ugt-62 Protein UGT-62 0.068
unc-78 Protein UNC-78 0.068
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
hspa5 heat shock protein 5 0.964
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.956
hyou1 hypoxia up-regulated 1 0.881
manf mesencephalic astrocyte-derived neurotrophic factor 0.856
hspd1 heat shock 60kD protein 1 (chaperonin) 0.826
dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.776
pdia3 protein disulfide isomerase family A, member 3 0.620
calr calreticulin and calreticulin 0.607
dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.547
tram1 translocating chain-associating membrane protein 1 0.545
pdip5 protein disulfide isomerase-related protein (provisional) 0.531
hspa9 heat shock protein 9 0.297
pdia4 protein disulfide isomerase associated 4 0.270
calrl calreticulin like 0.230
yars tyrosyl-tRNA synthetase 0.161
ckma creatine kinase, muscle a 0.159
ccng1 cyclin G1 0.143
canx calnexin 0.122
ttna titin a 0.122
calrl2 calreticulin, like 2 0.120
adra2b adrenergic, alpha-2B-, receptor 0.114
txnrd1 thioredoxin reductase 1 0.113
zgc:162630 zgc:162630 0.105
phb prohibitin 0.095
pvalb2 parvalbumin 2 0.094
slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.092
mylz3 myosin, light polypeptide 3, skeletal muscle 0.090
lars leucyl-tRNA synthetase 0.086
etf1 eukaryotic translation termination factor 1 0.085
ddost dolichyl-diphosphooligosaccharide-protein glycosyltransferase 0.083
zgc:153260 zgc:153260 0.082
nme2b.2 non-metastatic cells 2b.2, protein (NM23B) expressed in 0.080
hspa4a heat shock protein 4a 0.080
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.076
neb nebulin 0.074
prkcsh protein kinase C substrate 80K-H 0.072
rpl4 ribosomal protein L4 0.071
hsp90a.2 heat shock protein 90-alpha 2 0.069
march6 membrane-associated ring finger (C3HC4) 6 0.069
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.068
sec61al2 Sec61 alpha like 2 0.067
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.065
mtdha metadherin a 0.065
zgc:73136 zgc:73136 0.064
vmp1 vacuole membrane protein 1 0.064
tmed9 transmembrane emp24 protein transport domain containing 9 0.062
chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.061
zfp36l1a zinc finger protein 36, C3H type-like 1a 0.058
hspa8 heat shock protein 8 0.057
arfgef1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.056
ef1a elongation factor 1-alpha 0.054
zgc:152873 zgc:152873 0.054
nucb2b nucleobindin 2b 0.052
pvalb4 parvalbumin 4 0.052
mapkapk2a mitogen-activated protein kinase-activated protein kinase 2a 0.051
rpn2 ribophorin II 0.049
tpma alpha-tropomyosin 0.049
prdx3 peroxiredoxin 3 0.049
dirc2 disrupted in renal carcinoma 2 0.047
tufm Tu translation elongation factor, mitochondrial 0.046
pdap1 pdgfa associated protein 1 0.046
abcb3l1 ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 0.044
tnni2a.4 troponin I, skeletal, fast 2a.4 0.044
cyc1 cytochrome c-1 0.043
tmem170a transmembrane protein 170A 0.043
herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.043
syvn1 synovial apoptosis inhibitor 1, synoviolin 0.040
uqcrc1 ubiquinol-cytochrome c reductase core protein I 0.040
fzd7b frizzled homolog 7b 0.038
gclc glutamate-cysteine ligase, catalytic subunit 0.038
zgc:101724 zgc:101724 0.037
arf2 ADP-ribosylation factor 2 0.037
pdha1a pyruvate dehydrogenase (lipoamide) alpha 1a 0.036
tnnt3b troponin T3b, skeletal, fast 0.036
irf11 interferon regulatory factor 11 0.036
mbnl2 muscleblind-like 2 (Drosophila) 0.035
zbtb22b zinc finger and BTB domain containing 22b 0.035
keap1a kelch-like ECH-associated protein 1a 0.035
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.034
jun jun proto-oncogene 0.034
lonp1 lon peptidase 1, mitochondrial 0.034
ckmb creatine kinase, muscle b 0.034
lman1 lectin, mannose-binding, 1 0.033
tm9sf2 transmembrane 9 superfamily member 2 0.032
zgc:103668 zgc:103668 0.032
odc1 ornithine decarboxylase 1 0.032
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.032
ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.031
cdkrap3 CDK5 regulatory subunit associated protein 3 0.031
yipf3 Yip1 domain family, member 3 0.031
sqrdl sulfide quinone reductase-like (yeast) 0.031
desma desmin a 0.031
idh3b isocitrate dehydrogenase 3 (NAD+) beta 0.030
lap3 leucine aminopeptidase 3 0.030
ldb3b LIM domain binding 3b 0.029
tbc1d23 TBC1 domain family, member 23 0.029
stat3 signal transduction and activation of transcription 3 0.028
zgc:56419 zgc:56419 0.028
scamp2 secretory carrier membrane protein 2 0.028
papss2b 3'-phosphoadenosine 5'-phosphosulfate synthase 2b 0.028
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
BG4 CG12297 gene product from transcript CG12297-RA 0.052
Rel Relish 0.018
chico CG5686 gene product from transcript CG5686-RB 0.017
RagA CG11968 gene product from transcript CG11968-RA 0.015
Cat Catalase 0.012
path pathetic 0.011
CG7371 CG7371 gene product from transcript CG7371-RA 0.011
Traf4 TNF-receptor-associated factor 4 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SYVN1 synovial apoptosis inhibitor 1, synoviolin 1.000
PDIA3 protein disulfide isomerase family A, member 3 1.000
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.999
BCL2 B-cell CLL/lymphoma 2 0.993
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.991
BCL2L1 BCL2-like 1 0.983
VCP valosin containing protein 0.959
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.953
P4HB prolyl 4-hydroxylase, beta polypeptide 0.936
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.928
SELS selenoprotein S 0.908
DERL1 Der1-like domain family, member 1 0.884
CANX calnexin 0.849
BAX BCL2-associated X protein 0.806
HSPA8 heat shock 70kDa protein 8 0.774
PDIA6 protein disulfide isomerase family A, member 6 0.745
UBE2J1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) 0.740
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.691
BAD BCL2-associated agonist of cell death 0.631
ATF3 activating transcription factor 3 0.630
GHR growth hormone receptor 0.624
PDIA4 protein disulfide isomerase family A, member 4 0.621
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.455
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.443
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.430
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.349
BAK1 BCL2-antagonist/killer 1 0.306
VDAC1 voltage-dependent anion channel 1 0.275
ERO1L ERO1-like (S. cerevisiae) 0.262
GRB2 growth factor receptor-bound protein 2 0.245
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.230
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.212
SOS1 son of sevenless homolog 1 (Drosophila) 0.187
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.170
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.114
CALR calreticulin 0.109
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.109
CCND3 cyclin D3 0.097
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.086
ATF2 activating transcription factor 2 0.076
C4orf14 chromosome 4 open reading frame 14 0.070
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.067
DBP D site of albumin promoter (albumin D-box) binding protein 0.064
AMFR autocrine motility factor receptor 0.062
BAG1 BCL2-associated athanogene 0.061
ENO1 enolase 1, (alpha) 0.057
SSR1 signal sequence receptor, alpha 0.055
STON2 stonin 2 0.055
ERN1 endoplasmic reticulum to nucleus signaling 1 0.051
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.050
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.050
HSPH1 heat shock 105kDa/110kDa protein 1 0.049
RPN1 ribophorin I 0.048
CDK6 cyclin-dependent kinase 6 0.046
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.045
RABAC1 Rab acceptor 1 (prenylated) 0.041
TUFM Tu translation elongation factor, mitochondrial 0.039
RNF144B ring finger protein 144B 0.039
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.039
FKBP4 FK506 binding protein 4, 59kDa 0.038
NUCB2 nucleobindin 2 0.037
HYOU1 hypoxia up-regulated 1 0.037
ATXN3 ataxin 3 0.037
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.032
LDHA lactate dehydrogenase A 0.031
CDK4 cyclin-dependent kinase 4 0.030
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.028
CYCS cytochrome c, somatic 0.027
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.027
STX8 syntaxin 8 0.027
ERO1LB ERO1-like beta (S. cerevisiae) 0.027
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.026
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) 0.025
BAG2 BCL2-associated athanogene 2 0.025
BID BH3 interacting domain death agonist 0.024
RNR2 l-rRNA 0.023
NSFL1C NSFL1 (p97) cofactor (p47) 0.023
C19orf10 chromosome 19 open reading frame 10 0.023
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.022
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.022
HM13 histocompatibility (minor) 13 0.022
DERL2 Der1-like domain family, member 2 0.021
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.021
EIF1 eukaryotic translation initiation factor 1 0.020
LDLR low density lipoprotein receptor 0.020
RPN2 ribophorin II 0.020
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.019
GANAB glucosidase, alpha; neutral AB 0.019
EMD emerin 0.019
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.018
SERP1 stress-associated endoplasmic reticulum protein 1 0.018
USP46 ubiquitin specific peptidase 46 0.017
ANKRD12 ankyrin repeat domain 12 0.017
PLCG1 phospholipase C, gamma 1 0.017
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.017
DNM1 dynamin 1 0.017
TRAP1 TNF receptor-associated protein 1 0.016
HSPA13 heat shock protein 70kDa family, member 13 0.016
KEAP1 kelch-like ECH-associated protein 1 0.016
MOV10 Mov10, Moloney leukemia virus 10, homolog (mouse) 0.016
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Hspa5 heat shock protein 5 0.999
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.997
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.949
Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.882
Manf mesencephalic astrocyte-derived neurotrophic factor 0.817
Creld2 cysteine-rich with EGF-like domains 2 0.717
Pdia3 protein disulfide isomerase associated 3 0.714
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.705
Cdk4 cyclin-dependent kinase 4 0.634
Sdf2l1 stromal cell-derived factor 2-like 1 0.596
Vcp valosin containing protein 0.532
Cdk6 cyclin-dependent kinase 6 0.389
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.365
Pdia6 protein disulfide isomerase associated 6 0.364
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.318
Xbp1 X-box binding protein 1 0.294
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.286
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.247
Pycard PYD and CARD domain containing 0.239
Serp1 stress-associated endoplasmic reticulum protein 1 0.236
Hspa9 heat shock protein 9 0.230
Edem1 ER degradation enhancer, mannosidase alpha-like 1 0.223
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.201
Surf4 surfeit gene 4 0.199
Tlr4 toll-like receptor 4 0.194
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.181
Ncstn nicastrin 0.174
Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 0.171
H47 histocompatibility 47 0.167
Mgat2 mannoside acetylglucosaminyltransferase 2 0.158
Slc39a7 solute carrier family 39 (zinc transporter), member 7 0.154
Ssr2 signal sequence receptor, beta 0.150
Rpn2 ribophorin II 0.144
Calr calreticulin 0.144
Spcs3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.139
Hif1a hypoxia inducible factor 1, alpha subunit 0.137
Prkcsh protein kinase C substrate 80K-H 0.126
Ngly1 N-glycanase 1 0.123
P4hb prolyl 4-hydroxylase, beta polypeptide 0.111
Magt1 magnesium transporter 1 0.104
Fas Fas (TNF receptor superfamily member 6) 0.101
Slc30a5 solute carrier family 30 (zinc transporter), member 5 0.099
Trp53 transformation related protein 53 0.087
Slc35b1 solute carrier family 35, member B1 0.086
Stat3 signal transducer and activator of transcription 3 0.083
Casp1 caspase 1 0.081
Rpn1 ribophorin I 0.079
Uba5 ubiquitin-like modifier activating enzyme 5 0.076
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.075
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.073
Atf6 activating transcription factor 6 0.072
Bcl2 B-cell leukemia/lymphoma 2 0.071
Sec23b SEC23B (S. cerevisiae) 0.069
Tm9sf3 transmembrane 9 superfamily member 3 0.069
Ssr1 signal sequence receptor, alpha 0.061
Gbp5 guanylate binding protein 5 0.060
Il18 interleukin 18 0.060
Erp44 endoplasmic reticulum protein 44 0.051
Tram1 translocating chain-associating membrane protein 1 0.050
Rrbp1 ribosome binding protein 1 0.050
Gmppb GDP-mannose pyrophosphorylase B 0.048
Fndc3a fibronectin type III domain containing 3A 0.046
Canx calnexin 0.044
Ubxn1 UBX domain protein 1 0.044
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.043
Txndc5 thioredoxin domain containing 5 0.043
Myd88 myeloid differentiation primary response gene 88 0.043
Lman1 lectin, mannose-binding, 1 0.042
Nus1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 0.042
Tmed7 transmembrane emp24 protein transport domain containing 7 0.041
Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 0.040
Lyz2 lysozyme 2 0.038
Hspa8 heat shock protein 8 0.037
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.035
Ccnd1 cyclin D1 0.034
Atf4 activating transcription factor 4 0.033
Bak1 BCL2-antagonist/killer 1 0.032
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.032
Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 0.032
Hsph1 heat shock 105kDa/110kDa protein 1 0.032
Rb1 retinoblastoma 1 0.031
Yars tyrosyl-tRNA synthetase 0.030
Birc3 baculoviral IAP repeat-containing 3 0.030
Lrrc59 leucine rich repeat containing 59 0.030
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.030
Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.030
Ifngr1 interferon gamma receptor 1 0.030
Rag1 recombination activating gene 1 0.030
D4Wsu53e DNA segment, Chr 4, Wayne State University 53, expressed 0.029
Dnm1 dynamin 1 0.029
Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) 0.029
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.028
Rnf103 ring finger protein 103 0.028
Arhgap31 Rho GTPase activating protein 31 0.028
Sars seryl-aminoacyl-tRNA synthetase 0.027
Gars glycyl-tRNA synthetase 0.027
Eif3b eukaryotic translation initiation factor 3, subunit B 0.027
Mcfd2 multiple coagulation factor deficiency 2 0.027
Syvn1 synovial apoptosis inhibitor 1, synoviolin 0.025
Ssr3 signal sequence receptor, gamma 0.025
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Manf mesencephalic astrocyte-derived neurotrophic factor 0.136
Pdia3 protein disulfide isomerase family A, member 3 0.127
Hsp90b1 heat shock protein 90, beta, member 1 0.105
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.067
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.059
Pdia4 protein disulfide isomerase family A, member 4 0.053
Canx calnexin 0.049
Lrrc59 leucine rich repeat containing 59 0.047
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.034
Creld2 cysteine-rich with EGF-like domains 2 0.034
Pdia6 protein disulfide isomerase family A, member 6 0.033
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.031
Calr calreticulin 0.028
Ubxn4 UBX domain protein 4 0.027
Hsph1 heat shock 105/110 protein 1 0.022
Plscr3 phospholipid scramblase 3 0.020
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.019
Srpr signal recognition particle receptor ('docking protein') 0.017
Txnrd1 thioredoxin reductase 1 0.015
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.015
Nsfl1c NSFL1 (p97) cofactor (p47) 0.015
Hyou1 hypoxia up-regulated 1 0.014
Snd1 staphylococcal nuclease and tudor domain containing 1 0.014
Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.012
Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform 0.011
Btg1 B-cell translocation gene 1, anti-proliferative 0.011
Hspa5 heat shock protein 5 0.011
P4hb prolyl 4-hydroxylase, beta polypeptide 0.011
Hdlbp high density lipoprotein binding protein 0.011
Slc39a7 solute carrier family 39 (zinc transporter), member 7 0.011
Sec23b Sec23 homolog B (S. cerevisiae) 0.010
Ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.010
Yars tyrosyl-tRNA synthetase 0.010
Tax1bp3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SLT2 Slt2p 0.043
DER1 Der1p 0.038
USA1 Usa1p 0.037
HRD3 Hrd3p 0.035
RIM21 Rim21p 0.031
PMT3 Pmt3p 0.024
KSS1 Kss1p 0.024
SFB3 Sfb3p 0.020
KDX1 Kdx1p 0.020
MSG5 Msg5p 0.019
PMT2 Pmt2p 0.019
PRC1 Prc1p 0.018
PMT5 Pmt5p 0.017
KAR2 Kar2p 0.017
ERO1 Ero1p 0.017
KRE1 Kre1p 0.016
MCD4 Mcd4p 0.016
PMT1 Pmt1p 0.016
SCJ1 Scj1p 0.015
ALD6 Ald6p 0.015
PEP4 Pep4p 0.015
BST1 Bst1p 0.015
LHS1 Lhs1p 0.014
SPF1 Spf1p 0.014
IRE1 Ire1p 0.013
PPQ1 Ppq1p 0.013
RHO1 Rho1p 0.012
RLM1 Rlm1p 0.012
NGG1 Ngg1p 0.012
YIP4 Yip4p 0.012
CTI6 Cti6p 0.012
GLO3 Glo3p 0.011
BIG1 Big1p 0.011
JEM1 Jem1p 0.011
EUG1 Eug1p 0.011
BMH1 Bmh1p 0.011
ROT1 Rot1p 0.011
HDA2 Hda2p 0.011
ALG12 Alg12p 0.011
CRP1 Crp1p 0.011
UBC6 Ubc6p 0.011
RSN1 Rsn1p 0.011
GWT1 Gwt1p 0.011
FRK1 Frk1p 0.011
SEC59 Sec59p 0.011
KRE6 Kre6p 0.011
MDH2 Mdh2p 0.011
PDR12 Pdr12p 0.011
CWH43 Cwh43p 0.010
SRD1 Srd1p 0.010
URH1 Urh1p 0.010
SOK2 Sok2p 0.010
INO2 Ino2p 0.010
ADA2 Ada2p 0.010
FUS3 Fus3p 0.010
UBX7 Ubx7p 0.010
PCL9 Pcl9p 0.010
CHS1 Chs1p 0.010
PCL5 Pcl5p 0.010