The network for 'response to topologically incorrect protein' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to topologically incorrect protein

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
hsp-16.2 Protein HSP-16.2 0.993
abu-15 Protein ABU-15 0.992
hsp-16.1 Protein HSP-16.1 0.991
tag-320 Protein TAG-320 0.979
hsp-70 Protein HSP-70 0.978
F44E5.4 Protein F44E5.4 0.978
abu-11 Protein ABU-11 0.971
hsp-16.41 Protein HSP-16.41 0.967
abu-8 Protein ABU-8 0.960
hsp-3 Protein HSP-3 0.862
Y94H6A.7 Protein Y94H6A.7 0.840
CELE_F19B2.5 Protein F19B2.5 0.825
abu-1 Protein ABU-1 0.815
hsp-16.48 Protein HSP-16.48 0.777
dnj-7 Protein DNJ-7 0.762
hsp-4 Protein HSP-4 0.756
daf-21 Protein DAF-21 0.753
lys-1 Protein LYS-1 0.748
abu-6 Protein ABU-6 0.714
pdi-2 Protein PDI-2 0.701
abu-14 Protein ABU-14 0.690
pqn-54 Protein PQN-54 0.687
dnj-13 Protein DNJ-13 0.687
abu-10 Protein ABU-10 0.669
F54E2.1 Protein F54E2.1 0.658
Y47D3B.6 Protein Y47D3B.6 0.614
CELE_T06E4.8 Protein T06E4.8 0.606
hsp-1 Protein HSP-1 0.577
CELE_T05E11.3 Protein T05E11.3 0.559
hsp-17 Protein HSP-17 0.549
C29F3.7 Protein C29F3.7 0.496
F13E6.5 Protein F13E6.5 0.462
dsc-4 Protein DSC-4 0.459
dct-18 Protein DCT-18 0.455
pqn-63 Protein PQN-63 0.449
stt-3 Protein STT-3 0.441
nhr-17 Protein NHR-17 0.408
ifd-1 Protein IFD-1 0.374
Y76B12C.3 Protein Y76B12C.3 0.362
ckb-2 Protein CKB-2 0.337
C18A11.3 Protein C18A11.3 0.333
CELE_T06E4.9 Protein T06E4.9 0.326
pdi-3 Protein PDI-3 0.322
cnp-3 Protein CNP-3 0.305
cnx-1 Protein CNX-1 0.305
pqn-74 Protein PQN-74 0.279
abu-9 Protein ABU-9 0.253
sec-22 Protein SEC-22 0.224
prx-19 Protein PRX-19 0.220
F33D4.5 Protein F33D4.5 0.212
gst-1 Protein GST-1 0.208
mig-6 Protein MIG-6 0.194
T14G8.3 Protein T14G8.3 0.191
npl-4.2 Protein NPL-4.2 0.184
crt-1 Protein CRT-1 0.182
sgt-1 Protein SGT-1 0.176
R03C1.1 Protein R03C1.1 0.175
pqn-71 Protein PQN-71 0.173
tufm-1 Protein TUFM-1 0.173
C34H4.2 Protein C34H4.2 0.167
skn-1 Protein SKN-1 0.165
glod-4 Protein GLOD-4 0.163
rab-6.2 Protein RAB-6.2 0.162
lron-2 Protein LRON-2 0.156
D2096.6 Protein D2096.6 0.156
F44E7.4 Protein F44E7.4 0.155
pqn-32 Protein PQN-32 0.152
Y19D2B.1 Protein Y19D2B.1 0.150
R05F9.6 Protein R05F9.6 0.147
C35B1.5 Protein C35B1.5 0.144
haly-1 Protein HALY-1 0.144
nra-4 Protein NRA-4 0.140
unc-52 Protein UNC-52 0.138
grl-7 Protein GRL-7 0.136
F08H9.3 Protein F08H9.3 0.135
T10B10.3 Protein T10B10.3 0.133
E04A4.5 Protein E04A4.5 0.133
ifg-1 Protein IFG-1 0.132
M02G9.1 Protein M02G9.1 0.132
tnt-4 Protein TNT-4 0.131
F47G9.1 Protein F47G9.1 0.129
letm-1 Protein LETM-1 0.129
glrx-10 Protein GLRX-10 0.126
ser-3 Protein SER-3 0.125
mdt-28 Protein MDT-28 0.123
C31E10.6 Protein C31E10.6 0.121
CELE_F59B1.8 Protein F59B1.8 0.118
F08H9.4 Protein F08H9.4 0.116
paa-1 Protein PAA-1 0.115
ath-1 Protein ATH-1 0.113
F41E6.11 Protein F41E6.11 0.113
F53B3.3 Protein F53B3.3 0.113
acs-4 Protein ACS-4 0.112
CELE_C01G6.5 Protein C01G6.5 0.112
pst-2 Protein PST-2 0.112
vha-10 Protein VHA-10 0.111
imp-2 Protein IMP-2 0.107
F13H6.1 Protein F13H6.1 0.105
CELE_F20G2.2 Protein F20G2.2 0.104
gst-23 Protein GST-23 0.103
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.966
dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.734
manf mesencephalic astrocyte-derived neurotrophic factor 0.681
hyou1 hypoxia up-regulated 1 0.590
hspa5 heat shock protein 5 0.428
pdia4 protein disulfide isomerase associated 4 0.418
pdia3 protein disulfide isomerase family A, member 3 0.316
calr calreticulin and calreticulin 0.303
vmp1 vacuole membrane protein 1 0.280
hspa4a heat shock protein 4a 0.213
pdip5 protein disulfide isomerase-related protein (provisional) 0.197
yars tyrosyl-tRNA synthetase 0.194
mbnl2 muscleblind-like 2 (Drosophila) 0.187
calrl calreticulin like 0.183
canx calnexin 0.164
tram1 translocating chain-associating membrane protein 1 0.138
mtdha metadherin a 0.136
usp5 ubiquitin specific protease 5 0.135
mapkapk2a mitogen-activated protein kinase-activated protein kinase 2a 0.124
adra2b adrenergic, alpha-2B-, receptor 0.120
dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.119
mylz3 myosin, light polypeptide 3, skeletal muscle 0.117
calrl2 calreticulin, like 2 0.112
ccng1 cyclin G1 0.111
prkcsh protein kinase C substrate 80K-H 0.109
copb2 coatomer protein complex, subunit beta 2 0.106
dctn2 dynactin 2 (p50) 0.105
syvn1 synovial apoptosis inhibitor 1, synoviolin 0.104
tmed9 transmembrane emp24 protein transport domain containing 9 0.104
copg2 coatomer protein complex, subunit gamma 2 0.101
nr1d2b nuclear receptor subfamily 1, group D, member 2b 0.101
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.100
tmed2 transmembrane emp24 domain trafficking protein 2 0.098
cct5 chaperonin containing TCP1, subunit 5 (epsilon) 0.094
col1a2 collagen, type I, alpha 2 0.093
srpr signal recognition particle receptor (docking protein) 0.093
gspt1l G1 to S phase transition 1, like 0.091
id1 inhibitor of DNA binding 1 0.087
lars leucyl-tRNA synthetase 0.083
hsp90a.2 heat shock protein 90-alpha 2 0.078
txnrd1 thioredoxin reductase 1 0.078
dnaja1l DnaJ (Hsp40) homolog, subfamily A, member 1, like 0.076
abcb3l1 ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 0.075
eprs glutamyl-prolyl-tRNA synthetase 0.074
rpn2 ribophorin II 0.074
lonp2 lon peptidase 2, peroxisomal 0.072
zgc:153260 zgc:153260 0.070
arfgef1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.069
zgc:101724 zgc:101724 0.069
hsp90ab1 heat shock protein 90, alpha (cytosolic), class B member 1 0.067
tk2 thymidine kinase 2, mitochondrial 0.066
dnm1l dynamin 1-like 0.066
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.065
zgc:162630 zgc:162630 0.064
scamp2 secretory carrier membrane protein 2 0.064
vmhc ventricular myosin heavy chain 0.064
ef1a elongation factor 1-alpha 0.063
kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.063
furinb furin (paired basic amino acid cleaving enzyme) b 0.063
ipo7 importin 7 0.063
hdlbp high density lipoprotein-binding protein (vigilin) 0.061
cry-dash cryptochrome DASH 0.061
frem2a Fras1 related extracellular matrix protein 2a 0.060
rad54b RAD54 homolog B (S. cerevisiae) 0.059
mxa myxovirus (influenza) resistance A 0.058
pcsk1 proprotein convertase subtilisin/kexin type 1 0.058
pygmb phosphorylase, glycogen (muscle) b 0.058
march6 membrane-associated ring finger (C3HC4) 6 0.056
azin1b antizyme inhibitor 1b 0.056
tm9sf3 transmembrane 9 superfamily member 3 0.056
pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 0.056
gclc glutamate-cysteine ligase, catalytic subunit 0.056
ms4a17a.11 membrane-spanning 4-domains, subfamily A, member 17A.11 0.055
eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) 0.055
dnajb1a DnaJ (Hsp40) homolog, subfamily B, member 1a 0.053
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.052
herpud2 HERPUD family member 2 0.052
hspa8 heat shock protein 8 0.052
fezf2 FEZ family zinc finger 2 0.052
tlr22 toll-like receptor 22 0.052
itga3b integrin, alpha 3b 0.052
aars alanyl-tRNA synthetase 0.051
grb10a growth factor receptor-bound protein 10a 0.051
cald1 caldesmon 1 0.050
mospd1 motile sperm domain containing 1 0.050
si:ch211-173b8.2 si:ch211-173b8.2 0.050
tuba8l3 tubulin, alpha 8 like 3 0.048
hic1l hypermethylated in cancer 1 like 0.047
jun jun proto-oncogene 0.047
zgc:152896 zgc:152896 0.047
furina furin (paired basic amino acid cleaving enzyme) a 0.047
slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.046
ddost dolichyl-diphosphooligosaccharide-protein glycosyltransferase 0.046
hig1 hypoxia induced gene 1 0.046
ctgf connective tissue growth factor 0.045
casp9 caspase 9, apoptosis-related cysteine protease 0.044
pcsk7 proprotein convertase subtilisin/kexin type 7 0.044
tmem165 transmembrane protein 165 0.044
hspg2 heparan sulfate proteoglycan 2 0.044
nfe2l2 nuclear factor (erythroid-derived 2)-like 2 0.044
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
CG7830 CG7830 gene product from transcript CG7830-RA 0.251
Kr-h2 Kruppel homolog 2 0.163
CaBP1 CG5809 gene product from transcript CG5809-RA 0.143
CG5484 CG5484 gene product from transcript CG5484-RC 0.129
Spp Signal peptide protease 0.103
P58IPK CG8286 gene product from transcript CG8286-RA 0.095
KdelR KDEL receptor 0.088
Indy I'm not dead yet 0.070
Rel Relish 0.064
Traf4 TNF-receptor-associated factor 4 0.050
CG9318 CG9318 gene product from transcript CG9318-RA 0.049
Ero1L Endoplasmic reticulum oxidoreductin-1-like 0.046
CG3061 CG3061 gene product from transcript CG3061-RA 0.040
CG12404 CG12404 gene product from transcript CG12404-RA 0.039
CG30344 CG30344 gene product from transcript CG30344-RA 0.039
Der-2 Derlin-2 0.037
Spase25 Spase 25-subunit 0.034
kibra kibra ortholog 0.031
CG1418 CG1418 gene product from transcript CG1418-RA 0.031
mnd minidiscs 0.029
CG7371 CG7371 gene product from transcript CG7371-RA 0.028
CG12081 CG12081 gene product from transcript CG12081-RA 0.027
CG32581 CG32581 gene product from transcript CG32581-RB 0.026
TRAM CG11642 gene product from transcript CG11642-RB 0.024
Surf4 Surfeit 4 0.023
Rab7 Rab-protein 7 0.021
Fkbp13 CG9847 gene product from transcript CG9847-RC 0.020
Arr2 Arrestin 2 0.020
myoglianin CG1838 gene product from transcript CG1838-RD 0.020
desat1 CG5887 gene product from transcript CG5887-RA 0.019
Pdi Protein disulfide isomerase 0.018
flower CG6151 gene product from transcript CG6151-RA 0.018
CG5802 CG5802 gene product from transcript CG5802-RB 0.017
Rab14 Rab-protein 14 0.017
Sec61alpha CG9539 gene product from transcript CG9539-RA 0.016
Pak PAK-kinase 0.016
stv starvin 0.015
CG8974 CG8974 gene product from transcript CG8974-RD 0.015
CG3781 CG3781 gene product from transcript CG3781-RA 0.015
Plc21C Phospholipase C at 21C 0.015
Vha55 Vacuolar H[+]-ATPase 55kD B subunit 0.015
path pathetic 0.015
Dp1 Dodeca-satellite-binding protein 1 0.014
sec6 CG5341 gene product from transcript CG5341-RA 0.014
CG6126 CG6126 gene product from transcript CG6126-RA 0.014
Cat Catalase 0.013
CG10260 CG10260 gene product from transcript CG10260-RB 0.013
shrb shrub 0.013
Syx18 Syntaxin 18 0.013
milt milton 0.012
Dab Disabled 0.012
garz gartenzwerg 0.012
CG9590 CG9590 gene product from transcript CG9590-RA 0.012
CG17271 CG17271 gene product from transcript CG17271-RB 0.012
CG9706 CG9706 gene product from transcript CG9706-RA 0.012
CG8788 CG8788 gene product from transcript CG8788-RA 0.012
Pde8 Phosphodiesterase 8 0.011
Gcn2 CG1609 gene product from transcript CG1609-RA 0.011
crq croquemort 0.011
SuUR Suppressor of Under-Replication 0.010
mrj CG8448 gene product from transcript CG8448-RD 0.010
Herp Homocysteine-induced endoplasmic reticulum protein 0.010
CG15423 CG15423 gene product from transcript CG15423-RA 0.010
Vhl von Hippel-Lindau 0.010
MESR6 Misexpression suppressor of ras 6 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
VCP valosin containing protein 1.000
HSPA8 heat shock 70kDa protein 8 0.998
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.996
BCL2L1 BCL2-like 1 0.995
PDIA3 protein disulfide isomerase family A, member 3 0.987
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.958
HSPA1B heat shock 70kDa protein 1B 0.949
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.930
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.926
DERL1 Der1-like domain family, member 1 0.874
HSPA1A heat shock 70kDa protein 1A 0.796
P4HB prolyl 4-hydroxylase, beta polypeptide 0.784
BAG3 BCL2-associated athanogene 3 0.783
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.692
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.651
CANX calnexin 0.649
SELS selenoprotein S 0.643
PDIA4 protein disulfide isomerase family A, member 4 0.629
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.623
STON2 stonin 2 0.507
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.467
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.434
BAG2 BCL2-associated athanogene 2 0.390
UBE2J1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) 0.371
HSPB1 heat shock 27kDa protein 1 0.371
GHR growth hormone receptor 0.360
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.350
VDAC1 voltage-dependent anion channel 1 0.327
MET met proto-oncogene (hepatocyte growth factor receptor) 0.317
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.314
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.256
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.220
ATF3 activating transcription factor 3 0.215
BCL2 B-cell CLL/lymphoma 2 0.205
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.205
BAG1 BCL2-associated athanogene 0.202
BAX BCL2-associated X protein 0.172
C4orf14 chromosome 4 open reading frame 14 0.167
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.147
MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 0.146
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.131
NSFL1C NSFL1 (p97) cofactor (p47) 0.127
UFD1L ubiquitin fusion degradation 1 like (yeast) 0.127
WDR83 WD repeat domain 83 0.122
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.112
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.108
ERO1L ERO1-like (S. cerevisiae) 0.106
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.097
JUN jun proto-oncogene 0.096
AMFR autocrine motility factor receptor 0.095
HSPH1 heat shock 105kDa/110kDa protein 1 0.091
RPN1 ribophorin I 0.089
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.086
SOS1 son of sevenless homolog 1 (Drosophila) 0.085
ATXN3 ataxin 3 0.079
XIAP X-linked inhibitor of apoptosis 0.074
UBE2E3 ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) 0.072
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.068
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.062
CALR calreticulin 0.060
PTN pleiotrophin 0.057
PLAUR plasminogen activator, urokinase receptor 0.056
FOS FBJ murine osteosarcoma viral oncogene homolog 0.055
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.054
MKRN1 makorin ring finger protein 1 0.052
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.052
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.051
PTK2 PTK2 protein tyrosine kinase 2 0.050
HSF1 heat shock transcription factor 1 0.050
UBE4B ubiquitination factor E4B (UFD2 homolog, yeast) 0.048
HSPA4 heat shock 70kDa protein 4 0.046
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.046
UBXN2A UBX domain protein 2A 0.043
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.043
UBC ubiquitin C 0.043
FAF2 Fas associated factor family member 2 0.043
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.042
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.041
NCOR2 nuclear receptor corepressor 2 0.041
GANAB glucosidase, alpha; neutral AB 0.041
JUND jun D proto-oncogene 0.039
BAD BCL2-associated agonist of cell death 0.039
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.038
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.037
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.037
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.036
CCND3 cyclin D3 0.035
UBXN1 UBX domain protein 1 0.034
RNR2 l-rRNA 0.034
KEAP1 kelch-like ECH-associated protein 1 0.034
BAK1 BCL2-antagonist/killer 1 0.034
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.034
ATF2 activating transcription factor 2 0.033
UFM1 ubiquitin-fold modifier 1 0.033
USP46 ubiquitin specific peptidase 46 0.032
HYOU1 hypoxia up-regulated 1 0.031
GRB10 growth factor receptor-bound protein 10 0.031
RNF144B ring finger protein 144B 0.031
ERO1LB ERO1-like beta (S. cerevisiae) 0.031
KLHL24 kelch-like 24 (Drosophila) 0.031
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Hspa5 heat shock protein 5 1.000
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.999
Manf mesencephalic astrocyte-derived neurotrophic factor 0.994
Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.991
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.989
Creld2 cysteine-rich with EGF-like domains 2 0.975
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.919
Pdia3 protein disulfide isomerase associated 3 0.917
Pdia6 protein disulfide isomerase associated 6 0.830
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.817
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.752
Sdf2l1 stromal cell-derived factor 2-like 1 0.673
Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 0.656
Canx calnexin 0.642
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.579
Cdk4 cyclin-dependent kinase 4 0.540
Xbp1 X-box binding protein 1 0.523
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.505
Serp1 stress-associated endoplasmic reticulum protein 1 0.477
H47 histocompatibility 47 0.458
Cdk6 cyclin-dependent kinase 6 0.453
Gbp5 guanylate binding protein 5 0.394
Mgat2 mannoside acetylglucosaminyltransferase 2 0.363
Hsph1 heat shock 105kDa/110kDa protein 1 0.320
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.297
Magt1 magnesium transporter 1 0.295
Spcs3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.269
Edem1 ER degradation enhancer, mannosidase alpha-like 1 0.262
Calr calreticulin 0.247
Rpn1 ribophorin I 0.234
Pdia4 protein disulfide isomerase associated 4 0.228
Tram1 translocating chain-associating membrane protein 1 0.217
Surf4 surfeit gene 4 0.215
Slc30a5 solute carrier family 30 (zinc transporter), member 5 0.205
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.190
Iqcb1 IQ calmodulin-binding motif containing 1 0.180
Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.180
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.175
Il18 interleukin 18 0.173
P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide 0.161
Prnp prion protein 0.158
Hspa9 heat shock protein 9 0.154
Ncstn nicastrin 0.151
Fndc3a fibronectin type III domain containing 3A 0.150
Ngly1 N-glycanase 1 0.146
Psen1 presenilin 1 0.144
Erp44 endoplasmic reticulum protein 44 0.144
Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 0.130
Tm9sf3 transmembrane 9 superfamily member 3 0.116
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.116
Lman1 lectin, mannose-binding, 1 0.115
Ostc oligosaccharyltransferase complex subunit 0.109
Hspa8 heat shock protein 8 0.105
Tmed7 transmembrane emp24 protein transport domain containing 7 0.105
Derl2 Der1-like domain family, member 2 0.100
Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) 0.095
Tlr4 toll-like receptor 4 0.094
Ssr1 signal sequence receptor, alpha 0.093
Vcp valosin containing protein 0.093
Prkcsh protein kinase C substrate 80K-H 0.088
Rpgrip1l Rpgrip1-like 0.086
Tm9sf2 transmembrane 9 superfamily member 2 0.086
Cyld cylindromatosis (turban tumor syndrome) 0.084
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.083
Atf6 activating transcription factor 6 0.078
Hspa1b heat shock protein 1B 0.077
Arhgap31 Rho GTPase activating protein 31 0.075
2310036O22Rik RIKEN cDNA 2310036O22 gene 0.075
Sgpp1 sphingosine-1-phosphate phosphatase 1 0.074
Sec23b SEC23B (S. cerevisiae) 0.071
Tmem33 transmembrane protein 33 0.065
P4hb prolyl 4-hydroxylase, beta polypeptide 0.064
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.061
Hspd1 heat shock protein 1 (chaperonin) 0.059
Rab1 RAB1, member RAS oncogene family 0.056
Lonp1 lon peptidase 1, mitochondrial 0.055
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.055
Sqstm1 sequestosome 1 0.054
Ero1lb ERO1-like beta (S. cerevisiae) 0.051
0610007P14Rik RIKEN cDNA 0610007P14 gene 0.051
Aamp angio-associated migratory protein 0.050
Rpn2 ribophorin II 0.050
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.049
Ssr3 signal sequence receptor, gamma 0.048
Hspa1a heat shock protein 1A 0.047
Slc31a1 solute carrier family 31, member 1 0.046
Mcfd2 multiple coagulation factor deficiency 2 0.045
Amfr autocrine motility factor receptor 0.044
Ccnd1 cyclin D1 0.043
Bet1 blocked early in transport 1 homolog (S. cerevisiae) 0.043
Myd88 myeloid differentiation primary response gene 88 0.043
Pycard PYD and CARD domain containing 0.042
Yipf5 Yip1 domain family, member 5 0.042
Dnajb2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.041
Uba5 ubiquitin-like modifier activating enzyme 5 0.040
Bcl2 B-cell leukemia/lymphoma 2 0.040
Ccdc47 coiled-coil domain containing 47 0.040
Cd151 CD151 antigen 0.039
Tmed2 transmembrane emp24 domain trafficking protein 2 0.038
Ifngr1 interferon gamma receptor 1 0.038
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Hsph1 heat shock 105/110 protein 1 0.893
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.480
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.339
Hspd1 heat shock protein 1 (chaperonin) 0.239
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.069
Creld2 cysteine-rich with EGF-like domains 2 0.051
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.047
Stip1 stress-induced phosphoprotein 1 0.046
Chordc1 cysteine and histidine-rich domain (CHORD)-containing 1 0.035
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.026
Hspa5 heat shock protein 5 0.025
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.017
Hspa8 heat shock protein 8 0.016
LOC681996 similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 1 0.014
Hspb1 heat shock protein 1 0.012
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.011
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CDC48 Cdc48p 0.397
STI1 Sti1p 0.338
PMT2 Pmt2p 0.312
SSA2 Ssa2p 0.303
PMT1 Pmt1p 0.272
SSA4 Ssa4p 0.252
SSA3 Ssa3p 0.236
KSS1 Kss1p 0.184
SIS1 Sis1p 0.160
LHS1 Lhs1p 0.146
MSG5 Msg5p 0.140
HRD3 Hrd3p 0.120
YDJ1 Ydj1p 0.115
RLM1 Rlm1p 0.110
PMT3 Pmt3p 0.110
RIM21 Rim21p 0.107
SLT2 Slt2p 0.104
PMT5 Pmt5p 0.101
SGT2 Sgt2p 0.097
USA1 Usa1p 0.095
KRE1 Kre1p 0.095
SFB3 Sfb3p 0.086
AHA1 Aha1p 0.085
BTN2 Btn2p 0.084
SSA1 Ssa1p 0.080
SPF1 Spf1p 0.079
ERO1 Ero1p 0.077
DFM1 Dfm1p 0.075
YHB1 Yhb1p 0.072
UBA1 Uba1p 0.070
UBX7 Ubx7p 0.069
KAR2 Kar2p 0.069
SCJ1 Scj1p 0.068
UFD2 Ufd2p 0.067
UFD1 Ufd1p 0.066
MUB1 Mub1p 0.066
HDA2 Hda2p 0.063
YNL155W hypothetical protein 0.060
HMG2 Hmg2p 0.058
FUS3 Fus3p 0.053
PPQ1 Ppq1p 0.052
OTU1 Otu1p 0.050
CWH41 Cwh41p 0.049
ALD6 Ald6p 0.048
BFR1 Bfr1p 0.047
DER1 Der1p 0.045
PAR32 Par32p 0.044
KRE6 Kre6p 0.044
STE20 Ste20p 0.043
SOK2 Sok2p 0.043
CNE1 Cne1p 0.042
ADA2 Ada2p 0.042
OYE2 Oye2p 0.041
HRD1 Hrd1p 0.041
RPN2 Rpn2p 0.041
KTR1 Ktr1p 0.040
CAB3 Cab3p 0.040
SSM4 Ssm4p 0.040
SPT16 Spt16p 0.039
STE11 Ste11p 0.038
FPS1 Fps1p 0.038
JEM1 Jem1p 0.037
YOL098C hypothetical protein 0.037
RSN1 Rsn1p 0.036
PTC4 Ptc4p 0.035
STE5 Ste5p 0.035
SCS3 Scs3p 0.034
YPL088W hypothetical protein 0.034
SUB1 Sub1p 0.034
CRP1 Crp1p 0.033
PSD2 Psd2p 0.033
SCS7 Scs7p 0.033
ADR1 Adr1p 0.033
GLO3 Glo3p 0.033
BCK2 Bck2p 0.032
YIL108W hypothetical protein 0.032
ROM2 Rom2p 0.032
PCL9 Pcl9p 0.032
SSE2 Sse2p 0.031
TRA1 Tra1p 0.031
BET2 Bet2p 0.031
YOS9 Yos9p 0.031
UBC6 Ubc6p 0.031
CUR1 Cur1p 0.031
YIP4 Yip4p 0.031
PDR12 Pdr12p 0.030
HSP60 Hsp60p 0.030
MCD4 Mcd4p 0.030
KDX1 Kdx1p 0.030
HEM13 Hem13p 0.029
GPR1 Gpr1p 0.029
YIL151C hypothetical protein 0.029
URA3 Ura3p 0.029
PDI1 Pdi1p 0.029
TRS65 Trs65p 0.029
BST1 Bst1p 0.028
RGC1 Rgc1p 0.028
CMK2 Cmk2p 0.028
IRA1 Ira1p 0.028
KNH1 Knh1p 0.027