The network for 'mitotic recombination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitotic recombination

The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles.

Name Description Probability Func Analog Organism
RAD51 Rad51p 0.984
PCC1 Pcc1p 0.933
RAD1 Rad1p 0.850
RAD10 Rad10p 0.841
CGI121 Cgi121p 0.838
INO80 Ino80p 0.811
RAD59 Rad59p 0.806
MSH2 Msh2p 0.747
RAD52 Rad52p 0.725
SMC6 Smc6p 0.719
KAE1 Kae1p 0.714
GON7 Gon7p 0.706
EST2 Est2p 0.678
HST3 Hst3p 0.644
MMS22 Mms22p 0.643
MMS1 Mms1p 0.623
IES1 Ies1p 0.609
RAD55 Rad55p 0.586
SRS2 Srs2p 0.585
IES6 Ies6p 0.580
ARP4 Arp4p 0.574
RAD5 Rad5p 0.442
DNA2 Dna2p 0.437
YRF1-6 Yrf1-6p 0.418
EXO1 Exo1p 0.407
IES3 Ies3p 0.380
IES5 Ies5p 0.359
MSH3 Msh3p 0.353
YRF1-5 Yrf1-5p 0.341
YRF1-7 Yrf1-7p 0.337
MSH6 Msh6p 0.319
RMI1 Rmi1p 0.314
YRF1-3 Yrf1-3p 0.294
MRE11 Mre11p 0.282
RAD54 Rad54p 0.239
IRC8 Irc8p 0.236
DUN1 Dun1p 0.218
ASF1 Asf1p 0.217
RTT109 Rtt109p 0.208
GRX4 Grx4p 0.200
MEC1 Mec1p 0.199
MLH1 Mlh1p 0.193
YIL177C hypothetical protein 0.180
NHP10 Nhp10p 0.179
YRF1-1 Yrf1-1p 0.177
IES4 Ies4p 0.173
RAD14 Rad14p 0.169
EST1 Est1p 0.166
RAD50 Rad50p 0.162
IRC19 Irc19p 0.159
CTF4 Ctf4p 0.156
MMS4 Mms4p 0.155
ARP8 Arp8p 0.136
RRM3 Rrm3p 0.132
MMS21 Mms21p 0.114
PDR10 Pdr10p 0.111
RAD53 Rad53p 0.106
IRC5 Irc5p 0.101
HDA2 Hda2p 0.099
SUM1 Sum1p 0.094
RTT107 Rtt107p 0.093
RDH54 Rdh54p 0.093
YJL225C hypothetical protein 0.092
PEX12 Pex12p 0.090
YLR464W hypothetical protein 0.090
SAP30 Sap30p 0.087
DDC1 Ddc1p 0.082
YLR462W hypothetical protein 0.082
PMS1 Pms1p 0.081
NSE4 Nse4p 0.078
RAD17 Rad17p 0.078
WSS1 Wss1p 0.077
LIF1 Lif1p 0.077
HOR2 Hor2p 0.076
YEL077C hypothetical protein 0.076
TEL1 Tel1p 0.076
SPT2 Spt2p 0.075
ACE2 Ace2p 0.074
SGS1 Sgs1p 0.067
YER189W hypothetical protein 0.066
GYL1 Gyl1p 0.066
YLR049C hypothetical protein 0.066
GCR2 Gcr2p 0.066
ALK1 Alk1p 0.065
MUS81 Mus81p 0.064
YIR035C hypothetical protein 0.063
HIT1 Hit1p 0.062
SAW1 Saw1p 0.060
SRD1 Srd1p 0.059
SLX8 Slx8p 0.057
CDC13 Cdc13p 0.055
PEX2 Pex2p 0.055
RLF2 Rlf2p 0.054
SLX4 Slx4p 0.054
YLR264C-A hypothetical protein 0.050
KRE29 Kre29p 0.050
ULI1 Uli1p 0.050
POL31 Pol31p 0.049
YOL038C-A hypothetical protein 0.049
YER064C hypothetical protein 0.049
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pola2 polymerase (DNA directed), alpha 2 0.594
epb41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 0.573
mybl2 myeloblastosis oncogene-like 2 0.570
blm Bloom syndrome 0.461
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.376
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.351
msh2 mutS homolog 2 (E. coli) 0.290
zgc:100817 zgc:100817 0.224
zgc:92648 zgc:92648 0.204
si:ch211-1n9.7 si:ch211-1n9.7 0.193
prim1 primase polypeptide 1 0.146
rpa1 replication protein A1 0.135
esco2 establishment of cohesion 1 homolog 2 0.121
zgc:110540 zgc:110540 0.121
asf1bb ASF1 anti-silencing function 1 homolog Bb 0.118
recql5 RecQ protein-like 5 0.112
gins1 GINS complex subunit 1 (Psf1 homolog) 0.107
msh6 mutS homolog 6 (E. coli) 0.102
cdc45 CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.086
rbb4 retinoblastoma binding protein 4 0.079
dut dUTP pyrophosphatase 0.078
zgc:56197 zgc:56197 0.076
fen1 flap structure-specific endonuclease 1 0.071
pola1 polymerase (DNA directed), alpha 1 0.070
orc5 origin recognition complex, subunit 5 0.067
rpa2 replication protein A2 0.067
hspb2 heat shock protein, alpha-crystallin-related, b2 0.063
rnaseh2a ribonuclease H2, subunit A 0.063
ubr7 ubiquitin protein ligase E3 component n-recognin 7 0.063
hat1 histone acetyltransferase 1 0.060
rnaseh2b ribonuclease H2, subunit B 0.057
wdr76 WD repeat domain 76 0.057
zgc:154089 zgc:154089 0.052
racgap1 Rac GTPase-activating protein 1 0.052
zgc:92661 zgc:92661 0.050
hspb11 heat shock protein, alpha-crystallin-related, b11 0.047
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.046
chtf18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 0.046
wdr24 WD repeat domain 24 0.046
mus81 MUS81 endonuclease homolog (yeast) 0.044
cdk2 cyclin-dependent kinase 2 0.041
zgc:110113 zgc:110113 0.038
chek2 CHK2 checkpoint homolog (S. pombe) 0.037
wu:fa96e12 wu:fa96e12 0.037
rpa3 replication protein A3 0.036
actr8 ARP8 actin-related protein 8 homolog (yeast) 0.034
lrwd1 leucine-rich repeats and WD repeat domain containing 1 0.033
dpp3 dipeptidylpeptidase 3 0.032
zgc:92867 zgc:92867 0.029
rrm1 ribonucleotide reductase M1 polypeptide 0.029
tomm22 translocase of outer mitochondrial membrane 22 homolog (yeast) 0.029
hspb12 heat shock protein, alpha-crystallin-related, b12 0.026
zgc:113143 zgc:113143 0.026
vps37a vacuolar protein sorting 37A 0.023
slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 0.023
prom1a prominin 1a 0.022
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.022
poc1a POC1 centriolar protein homolog A (Chlamydomonas) 0.022
itfg2 integrin alpha FG-GAP repeat containing 2 0.022
zgc:55671 zgc:55671 0.022
efcab7 EF-hand calcium binding domain 7 0.021
sub1 SUB1 homolog (S. cerevisiae) 0.021
im:6898523 im:6898523 0.020
sephs1 selenophosphate synthetase 1 0.020
ift81 intraflagellar transport 81 homolog 0.020
usp5 ubiquitin specific protease 5 0.020
slc30a2 solute carrier family 30 (zinc transporter), member 2 0.020
npat nuclear protein, ataxia-telangiectasia locus 0.019
cdc7 cell division cycle 7 homolog (S. cerevisiae) 0.019
rbb4l retinoblastoma binding protein 4, like 0.019
rfc5 replication factor C (activator 1) 5 0.018
cpsf3l cleavage and polyadenylation specific factor 3-like 0.018
zgc:86841 zgc:86841 0.018
zgc:56706 zgc:56706 0.018
pms1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.018
zgc:63962 zgc:63962 0.018
tbcb tubulin folding cofactor B 0.017
hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 0.017
mlh1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) 0.017
gpatch1 G patch domain containing 1 0.017
zw10 ZW10 homolog, centromere/kinetochore protein (Drosophila) 0.017
cdc23 CDC23 (cell division cycle 23, yeast, homolog) 0.017
hspb9 heat shock protein, alpha-crystallin-related, 9 0.016
senp6a SUMO1/sentrin specific peptidase 6a 0.016
sybl1 synaptobrevin-like 1 0.016
rad1 RAD1 homolog (S. pombe) 0.016
zgc:123194 zgc:123194 0.016
zgc:73230 zgc:73230 0.016
zgc:55943 zgc:55943 0.016
mcm7 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.016
zgc:77165 zgc:77165 0.016
rnf17 ring finger protein 17 0.016
zgc:174506 zgc:174506 0.015
orc1 origin recognition complex, subunit 1 0.015
anapc5 anaphase promoting complex subunit 5 0.015
uck2b uridine-cytidine kinase 2b 0.015
chek1 CHK1 checkpoint homolog (S. pombe) 0.015
slc25a33 solute carrier family 25, member 33 0.015
maea macrophage erythroblast attacher 0.015
bmpr1bb bone morphogenetic protein receptor, type 1bb 0.015
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Drosophila melanogaster
Name Description Probability Func Analog Organism
okr okra 0.774
mus205 mutagen-sensitive 205 0.657
mus301 mutagen-sensitive 301 0.587
nbs CG6754 gene product from transcript CG6754-RC 0.547
mus101 mutagen-sensitive 101 0.510
Smc5 CG32438 gene product from transcript CG32438-RE 0.489
CG5524 CG5524 gene product from transcript CG5524-RA 0.457
mei-9 meiotic 9 0.334
stwl stonewall 0.243
Irbp Inverted repeat-binding protein 0.159
mus304 mutagen-sensitive 304 0.125
Brca2 Breast cancer 2, early onset homolog 0.100
lok loki 0.095
mus309 mutagen-sensitive 309 0.089
spn-B spindle B 0.080
mre11 meiotic recombination 11 0.080
pie pineapple eye 0.076
Ndc80 CG9938 gene product from transcript CG9938-RA 0.069
CG7376 CG7376 gene product from transcript CG7376-RA 0.051
Rev1 CG12189 gene product from transcript CG12189-RA 0.048
spn-D spindle D 0.043
mi minus 0.042
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.040
spn-E spindle E 0.034
tefu telomere fusion 0.033
CG2694 CG2694 gene product from transcript CG2694-RA 0.032
Utx CG5640 gene product from transcript CG5640-RD 0.023
Nup160 Nucleoporin 160 0.022
mrn marionette 0.021
CG9752 CG9752 gene product from transcript CG9752-RA 0.021
orb oo18 RNA-binding protein 0.021
nopo no poles 0.020
Su(fu) Suppressor of fused 0.019
CG5857 CG5857 gene product from transcript CG5857-RA 0.019
Cap-D3 Chromosome associated protein D3 0.018
dimm dimmed 0.018
dmt dalmatian 0.018
CG10722 CG10722 gene product from transcript CG10722-RA 0.017
mei-S332 meiotic from via Salaria 332 0.017
CG7183 CG7183 gene product from transcript CG7183-RA 0.017
CG33057 CG33057 gene product from transcript CG33057-RA 0.016
DNApol-alpha50 DNA polymerase alpha 50kD 0.016
CG4771 CG4771 gene product from transcript CG4771-RA 0.016
CG9967 CG9967 gene product from transcript CG9967-RA 0.016
Grip75 CG6176 gene product from transcript CG6176-RA 0.015
CG5731 CG5731 gene product from transcript CG5731-RA 0.015
CG9114 CG9114 gene product from transcript CG9114-RA 0.015
spn-A spindle A 0.015
Xpd Xeroderma pigmentosum D 0.014
CG5568 CG5568 gene product from transcript CG5568-RA 0.014
CG15861 CG15861 gene product from transcript CG15861-RA 0.013
MED17 Mediator complex subunit 17 0.012
CG3038 CG3038 gene product from transcript CG3038-RB 0.012
rnh1 ribonuclease H1 0.012
CG1103 CG1103 gene product from transcript CG1103-RA 0.012
mars CG17064 gene product from transcript CG17064-RB 0.012
sub subito 0.011
WRNexo WRN exonuclease 0.010
cdc16 CG6759 gene product from transcript CG6759-RA 0.010
CG18271 CG18271 gene product from transcript CG18271-RB 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.995
H2AFX H2A histone family, member X 0.914
BLM Bloom syndrome, RecQ helicase-like 0.888
BRCA1 breast cancer 1, early onset 0.839
WRN Werner syndrome, RecQ helicase-like 0.817
RAD51L3 RAD51-like 3 (S. cerevisiae) 0.635
BRCA2 breast cancer 2, early onset 0.591
MSH6 mutS homolog 6 (E. coli) 0.563
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.288
RAD51C RAD51 homolog C (S. cerevisiae) 0.222
C19orf39 chromosome 19 open reading frame 39 0.210
RPA1 replication protein A1, 70kDa 0.200
FANCD2 Fanconi anemia, complementation group D2 0.173
PARP1 poly (ADP-ribose) polymerase 1 0.172
NBN nibrin 0.142
RAD52 RAD52 homolog (S. cerevisiae) 0.134
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.130
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.111
RAD51L1 RAD51-like 1 (S. cerevisiae) 0.099
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 0.099
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.089
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.078
MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) 0.076
RPA3 replication protein A3, 14kDa 0.069
YY1 YY1 transcription factor 0.067
SLX4 SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) 0.060
RAD18 RAD18 homolog (S. cerevisiae) 0.054
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.051
MDC1 mediator of DNA-damage checkpoint 1 0.044
RPA2 replication protein A2, 32kDa 0.042
OSGEP O-sialoglycoprotein endopeptidase 0.040
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.035
EXO1 exonuclease 1 0.027
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.027
ATR ataxia telangiectasia and Rad3 related 0.021
TERF2 telomeric repeat binding factor 2 0.021
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 0.019
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) 0.018
RAD50 RAD50 homolog (S. cerevisiae) 0.018
ZSWIM7 zinc finger, SWIM-type containing 7 0.015
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.014
NDNL2 necdin-like 2 0.012
TOPBP1 topoisomerase (DNA) II binding protein 1 0.012
MSH3 mutS homolog 3 (E. coli) 0.011
ATM ataxia telangiectasia mutated 0.011
TP53RK TP53 regulating kinase 0.011
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.010
TP53BP1 tumor protein p53 binding protein 1 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Brca1 breast cancer 1 0.379
Brca2 breast cancer 2 0.306
Prim1 DNA primase, p49 subunit 0.189
Nup85 nucleoporin 85 0.172
Mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.148
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.121
Cenpk centromere protein K 0.095
Trip13 thyroid hormone receptor interactor 13 0.089
Smc4 structural maintenance of chromosomes 4 0.089
Pou5f1 POU domain, class 5, transcription factor 1 0.085
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.074
Dtl denticleless homolog (Drosophila) 0.066
Mms22l MMS22-like, DNA repair protein 0.060
Nup93 nucleoporin 93 0.058
Hells helicase, lymphoid specific 0.056
C330027C09Rik RIKEN cDNA C330027C09 gene 0.055
Smc2 structural maintenance of chromosomes 2 0.054
Rad51ap1 RAD51 associated protein 1 0.054
Zscan4b zinc finger and SCAN domain containing 4B 0.052
Bub1 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) 0.044
Haus6 HAUS augmin-like complex, subunit 6 0.044
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.042
Fen1 flap structure specific endonuclease 1 0.041
Cdc7 cell division cycle 7 (S. cerevisiae) 0.041
Rttn rotatin 0.039
Pold3 polymerase (DNA-directed), delta 3, accessory subunit 0.039
Dna2 DNA replication helicase 2 homolog (yeast) 0.039
Blm Bloom syndrome, RecQ helicase-like 0.037
Anln anillin, actin binding protein 0.036
Chek1 checkpoint kinase 1 homolog (S. pombe) 0.034
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.033
Dnajc9 DnaJ (Hsp40) homolog, subfamily C, member 9 0.032
Mnd1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 0.032
Gins1 GINS complex subunit 1 (Psf1 homolog) 0.032
Rfc2 replication factor C (activator 1) 2 0.032
Rfc1 replication factor C (activator 1) 1 0.031
Eif4a2 eukaryotic translation initiation factor 4A2 0.030
Topbp1 topoisomerase (DNA) II binding protein 1 0.029
Dnmt3b DNA methyltransferase 3B 0.029
Pola1 polymerase (DNA directed), alpha 1 0.028
Ttk Ttk protein kinase 0.028
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.027
Mis18bp1 MIS18 binding protein 1 0.027
Supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.027
Lrr1 leucine rich repeat protein 1 0.026
Orc1 origin recognition complex, subunit 1 0.026
Thoc3 THO complex 3 0.026
Rrm1 ribonucleotide reductase M1 0.026
Nup107 nucleoporin 107 0.025
Pms2 postmeiotic segregation increased 2 (S. cerevisiae) 0.024
Tipin timeless interacting protein 0.024
Mphosph9 M-phase phosphoprotein 9 0.024
Plk4 polo-like kinase 4 (Drosophila) 0.022
Stil Scl/Tal1 interrupting locus 0.021
Lims1 LIM and senescent cell antigen-like domains 1 0.021
Hist3h2bb-ps histone cluster 3, H2bb, pseudogene 0.020
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.020
Timeless timeless homolog (Drosophila) 0.020
Igh immunoglobulin heavy chain complex 0.019
Vrk1 vaccinia related kinase 1 0.019
Ncapg2 non-SMC condensin II complex, subunit G2 0.019
Xab2 XPA binding protein 2 0.019
Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.019
Prim2 DNA primase, p58 subunit 0.019
Lin9 lin-9 homolog (C. elegans) 0.018
Ipo11 importin 11 0.018
Exo1 exonuclease 1 0.018
Itfg1 integrin alpha FG-GAP repeat containing 1 0.018
Cdca7 cell division cycle associated 7 0.017
Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.017
Mgea5 meningioma expressed antigen 5 (hyaluronidase) 0.017
Fancm Fanconi anemia, complementation group M 0.016
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.016
BC055324 cDNA sequence BC055324 0.016
Rab18 RAB18, member RAS oncogene family 0.016
Mlh1 mutL homolog 1 (E. coli) 0.016
Brip1 BRCA1 interacting protein C-terminal helicase 1 0.016
Lig1 ligase I, DNA, ATP-dependent 0.016
Polb polymerase (DNA directed), beta 0.015
Ints9 integrator complex subunit 9 0.015
Tcf12 transcription factor 12 0.015
Hsbp1 heat shock factor binding protein 1 0.015
Kif2c kinesin family member 2C 0.015
Coro1b coronin, actin binding protein 1B 0.015
Rad18 RAD18 homolog (S. cerevisiae) 0.014
Sae1 SUMO1 activating enzyme subunit 1 0.014
Rpa1 replication protein A1 0.014
Ccne2 cyclin E2 0.014
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.014
Krit1 KRIT1, ankyrin repeat containing 0.014
Rfc4 replication factor C (activator 1) 4 0.014
Sgol1 shugoshin-like 1 (S. pombe) 0.013
Incenp inner centromere protein 0.013
Tex9 testis expressed gene 9 0.013
Ccne1 cyclin E1 0.013
Dnmt3a DNA methyltransferase 3A 0.013
Zfp942 zinc finger protein 942 0.013
Tacc3 transforming, acidic coiled-coil containing protein 3 0.013
Tex264 testis expressed gene 264 0.013
Nasp nuclear autoantigenic sperm protein (histone-binding) 0.013
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Rattus norvegicus
Name Description Probability Func Analog Organism