The network for 'protein modification by small protein conjugation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein modification by small protein conjugation

A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CDC16 Cdc16p 0.995
UBC4 Ubc4p 0.963
MND2 Mnd2p 0.959
DOC1 Doc1p 0.942
SWM1 Swm1p 0.923
CDC23 Cdc23p 0.923
APC2 Apc2p 0.892
CTR9 Ctr9p 0.885
CDC27 Cdc27p 0.863
APC9 Apc9p 0.838
RAD18 Rad18p 0.827
APC5 Apc5p 0.822
ELC1 Elc1p 0.811
UBC13 Ubc13p 0.802
ECM11 Ecm11p 0.792
RAD23 Rad23p 0.783
SLX8 Slx8p 0.770
RPT6 Rpt6p 0.742
PEX10 Pex10p 0.733
CDC53 Cdc53p 0.725
APC11 Apc11p 0.691
ULA1 Ula1p 0.690
CDC26 Cdc26p 0.682
UBR1 Ubr1p 0.667
SKP1 Skp1p 0.659
IKI1 Iki1p 0.647
SIZ1 Siz1p 0.640
RPN4 Rpn4p 0.634
UBP14 Ubp14p 0.625
URM1 Urm1p 0.620
CKA1 Cka1p 0.608
HRT1 Hrt1p 0.603
RAD6 Rad6p 0.598
APC4 Apc4p 0.595
RTF1 Rtf1p 0.570
KAR2 Kar2p 0.563
CDC48 Cdc48p 0.561
DMA2 Dma2p 0.555
SLX5 Slx5p 0.539
CDC6 Cdc6p 0.534
CDC4 Cdc4p 0.521
PAF1 Paf1p 0.520
NMD2 Nmd2p 0.514
RTT101 Rtt101p 0.505
UBA4 Uba4p 0.504
MOT2 Mot2p 0.496
APC1 Apc1p 0.487
LAG2 Lag2p 0.466
DST1 Dst1p 0.437
ATG9 Atg9p 0.426
ELP4 Elp4p 0.402
BUL1 Bul1p 0.396
CAK1 Cak1p 0.395
MRS6 Mrs6p 0.387
DAS1 Das1p 0.381
SGV1 Sgv1p 0.379
ULP1 Ulp1p 0.376
CDC34 Cdc34p 0.375
UFD4 Ufd4p 0.368
CKB1 Ckb1p 0.367
MET30 Met30p 0.363
PEX22 Pex22p 0.358
SGS1 Sgs1p 0.357
SSE1 Sse1p 0.356
IME2 Ime2p 0.354
MND1 Mnd1p 0.347
RAD50 Rad50p 0.345
RFA1 Rfa1p 0.335
TAE2 Tae2p 0.332
PDS1 Pds1p 0.324
ETP1 Etp1p 0.323
SSA3 Ssa3p 0.321
UFO1 Ufo1p 0.312
UBR2 Ubr2p 0.310
IKI3 Iki3p 0.310
DCN1 Dcn1p 0.304
SPT16 Spt16p 0.299
SET2 Set2p 0.295
RFA2 Rfa2p 0.286
NCS6 Ncs6p 0.286
CKB2 Ckb2p 0.285
ZIP1 Zip1p 0.281
HRT3 Hrt3p 0.281
HFM1 Hfm1p 0.279
MUB1 Mub1p 0.263
HIR1 Hir1p 0.260
UBC12 Ubc12p 0.259
LHS1 Lhs1p 0.256
PEX4 Pex4p 0.251
MKS1 Mks1p 0.247
RUB1 Rub1p 0.245
POL30 Pol30p 0.245
YDR506C hypothetical protein 0.238
ZIP2 Zip2p 0.235
POB3 Pob3p 0.229
DEG1 Deg1p 0.218
BTN2 Btn2p 0.213
AHC1 Ahc1p 0.206
HTA1 Hta1p 0.203
NFI1 Nfi1p 0.197
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
zyg-1 Protein ZYG-1 0.037
egl-18 Protein EGL-18 0.033
rpt-2 Protein RPT-2 0.032
ubr-1 Protein UBR-1 0.031
taf-5 Protein TAF-5 0.030
rpn-7 Protein RPN-7 0.028
rpn-3 Protein RPN-3 0.028
F58B3.6 Protein F58B3.6 0.027
C13F10.5 Protein C13F10.5 0.026
hrdl-1 Protein HRDL-1 0.026
R05F9.9 Protein R05F9.9 0.026
sym-4 Protein SYM-4 0.024
stam-1 Protein STAM-1 0.024
pap-1 Protein PAP-1 0.024
pqn-59 Protein PQN-59 0.022
egl-8 Protein EGL-8 0.021
F08B4.7 Protein F08B4.7 0.021
ptc-1 Protein PTC-1 0.020
H24G06.1 Protein H24G06.1 0.019
CELE_T26A8.4 Protein T26A8.4 0.019
T26A5.8 Protein T26A5.8 0.019
eya-1 Protein EYA-1 0.019
dnj-19 Protein DNJ-19 0.018
K04G7.1 Protein K04G7.1 0.018
rbx-1 Protein RBX-1 0.018
rab-5 Protein RAB-5 0.018
wdfy-2 Protein WDFY-2 0.018
rpn-6.1 Protein RPN-6.1 0.017
daf-21 Protein DAF-21 0.017
hgrs-1 Protein HGRS-1 0.017
rab-14 Protein RAB-14 0.017
T11G6.8 Protein T11G6.8 0.017
unc-73 Protein UNC-73 0.017
sel-12 Protein SEL-12 0.017
mbk-1 Protein MBK-1 0.017
elc-1 Protein ELC-1 0.017
nud-2 Protein NUD-2 0.016
ztf-7 Protein ZTF-7 0.016
ceh-44 Protein CEH-44 0.016
tba-2 Protein TBA-2 0.016
dpy-30 Protein DPY-30 0.016
lin-23 Protein LIN-23 0.015
spc-1 Protein SPC-1 0.015
atg-18 Protein ATG-18 0.015
W09D10.1 Protein W09D10.1 0.015
srgp-1 Protein SRGP-1 0.015
hpk-1 Protein HPK-1 0.015
mak-2 Protein MAK-2 0.015
lin-53 Protein LIN-53 0.015
rpa-1 Protein RPA-1 0.015
arl-8 Protein ARL-8 0.015
F44B9.5 Protein F44B9.5 0.015
dsh-2 Protein DSH-2 0.015
F28B3.1 Protein F28B3.1 0.015
cfim-2 Protein CFIM-2 0.014
B0041.5 Protein B0041.5 0.014
fbxa-192 Protein FBXA-192 0.014
M106.3 Protein M106.3 0.014
sli-1 Protein SLI-1 0.014
F56A6.4 Protein F56A6.4 0.014
flt-1 Protein FLT-1 0.014
ZK1055.7 Protein ZK1055.7 0.014
T24B8.2 Protein T24B8.2 0.014
Y50D7A.8 Protein Y50D7A.8 0.014
hpl-2 Protein HPL-2 0.014
rpn-11 Protein RPN-11 0.013
tim-1 Protein TIM-1 0.013
cul-2 Protein CUL-2 0.013
dnj-23 Protein DNJ-23 0.013
ilys-4 Protein ILYS-4 0.013
B0336.3 Protein B0336.3 0.013
eef-2 Protein EEF-2 0.013
pup-2 Protein PUP-2 0.013
snfc-5 Protein SNFC-5 0.013
rhgf-2 Protein RHGF-2 0.013
C14C10.5 Protein C14C10.5 0.013
F37B4.10 Protein F37B4.10 0.013
hda-2 Protein HDA-2 0.013
tag-298 Protein TAG-298 0.013
nhr-45 Protein NHR-45 0.013
D1044.6 Protein D1044.6 0.013
ubc-3 Protein UBC-3 0.013
nos-3 Protein NOS-3 0.012
aex-3 Protein AEX-3 0.012
rpn-10 Protein RPN-10 0.012
syx-17 Protein SYX-17 0.012
tba-1 Protein TBA-1 0.012
eif-3.B Protein EIF-3.B 0.012
zim-2 Protein ZIM-2 0.012
eea-1 Protein EEA-1 0.012
hsp-1 Protein HSP-1 0.012
ntl-4 Protein NTL-4 0.012
C34B2.5 Protein C34B2.5 0.012
egl-15 Protein EGL-15 0.012
cids-2 Protein CIDS-2 0.012
sma-6 Protein SMA-6 0.012
D1081.8 Protein D1081.8 0.012
sig-7 Protein SIG-7 0.012
F55F8.9 Protein F55F8.9 0.012
CELE_C25A1.4 Protein C25A1.4 0.012
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.063
tp53 tumor protein p53 0.052
cry5 cryptochrome 5 0.034
cops3 COP9 constitutive photomorphogenic homolog subunit 3 0.033
ccnb1 cyclin B1 0.032
cdh2 cadherin 2, neuronal 0.031
nod1 nucleotide-binding oligomerization domain containing 1 0.025
zgc:55347 zgc:55347 0.024
senp3a SUMO1/sentrin/SMT3 specific peptidase 3a 0.024
ugt1b1 UDP glucuronosyltransferase 1 family, polypeptide B1 0.024
smarcb1a SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a 0.024
zgc:55573 zgc:55573 0.023
psmd11b proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b 0.021
tshz1 teashirt family zinc finger 1 0.021
lmo4a LIM domain only 4a 0.021
fmr1 fragile X mental retardation 1 0.020
pppde1 PPPDE peptidase domain containing 1 0.020
foxd3 forkhead box D3 0.020
sirt1 sirtuin (silent mating type information regulation 2 homolog) 1 0.018
rybpa RING1 and YY1 binding protein a 0.018
gmnn geminin, DNA replication inhibitor 0.017
maea macrophage erythroblast attacher 0.016
evx1 even-skipped homeobox 1 0.016
ube2d2 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) 0.015
siah1 seven in absentia homolog 1 (Drosophila) 0.015
rbb4l retinoblastoma binding protein 4, like 0.015
tial1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.015
rhot1a ras homolog gene family, member T1a 0.015
zgc:86903 zgc:86903 0.015
lef1 lymphocyte enhancer binding factor 1 0.015
h2afv H2A histone family, member V 0.015
ogt.2 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2 0.014
ppil4 peptidylprolyl isomerase (cyclophilin)-like 4 0.014
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.014
dnaja2l DnaJ (Hsp40) homolog, subfamily A, member 2, like 0.014
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.013
admp anti-dorsalizing morphogenic protein 0.013
mkrn2 makorin, ring finger protein, 2 0.013
smfn small fragment nuclease 0.013
ythdf3 YTH domain family 3 0.013
dcaf7 ddb1 and cul4 associated factor 7 0.013
manf mesencephalic astrocyte-derived neurotrophic factor 0.013
nasp nuclear autoantigenic sperm protein (histone-binding) 0.013
ppp2r5eb protein phosphatase 2, regulatory subunit B', epsilon isoform b 0.012
csnk1db casein kinase 1, delta b 0.012
asf1bb ASF1 anti-silencing function 1 homolog Bb 0.012
eif1b eukaryotic translation initiation factor 1B 0.012
cdt1 chromatin licensing and DNA replication factor 1 0.012
nanos3 nanos homolog 3 0.012
mapk3 mitogen-activated protein kinase 3 0.012
nop14 NOP14 nucleolar protein homolog (yeast) 0.012
dynlrb1 dynein, light chain, roadblock-type 1 0.012
ror2 receptor tyrosine kinase-like orphan receptor 2 0.012
ufsp2 ufm1-specific peptidase 2 0.012
tubgcp2 tubulin, gamma complex associated protein 2 0.012
snx12 sorting nexin 12 0.012
lsm4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.011
hirip5 HIRA interacting protein 5 0.011
crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.011
ube2a ubiquitin-conjugating enzyme E2A (RAD6 homolog) 0.011
vdra vitamin D receptor a 0.011
taf8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.011
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.011
dda1 DET1 and DDB1 associated 1 0.011
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.011
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.011
mapk7 mitogen-activated protein kinase 7 0.011
ck2a2a casein kinase 2 alpha 2a 0.011
ripk2 receptor-interacting serine-threonine kinase 2 0.011
zgc:73100 zgc:73100 0.011
epb4.1l4 erythrocyte protein band 4.1-like 4 0.011
fkbp1aa FK506 binding protein 1Aa 0.011
tbc1d23 TBC1 domain family, member 23 0.011
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.011
fbxw2 F-box and WD repeat domain containing 2 0.010
snrpe small nuclear ribonucleoprotein polypeptide E 0.010
prmt5 protein arginine methyltransferase 5 0.010
hist2h2l histone 2, H2, like 0.010
csnk1g2a casein kinase 1, gamma 2a 0.010
rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.010
bmi1b B lymphoma Mo-MLV insertion region 1b 0.010
foxo3b forkhead box O3b 0.010
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Su(H) Suppressor of Hairless 0.912
jing CG9397 gene product from transcript CG9397-RI 0.821
lin19 lin-19-like 0.809
ago archipelago 0.787
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.709
Ras85D Ras oncogene at 85D 0.686
fs(1)h female sterile (1) homeotic 0.683
Cul-3 Cullin-3 0.631
hpo hippo 0.597
eff effete 0.534
slmb supernumerary limbs 0.523
Vps26 Vacuolar protein sorting 26 0.510
Atg1 Autophagy-specific gene 1 0.503
bon bonus 0.479
ci cubitus interruptus 0.468
kis kismet 0.445
Nedd8 CG10679 gene product from transcript CG10679-RA 0.405
Mad Mothers against dpp 0.385
UbcD2 Ubiquitin conjugating enzyme 2 0.378
park parkin 0.364
msl-1 male-specific lethal 1 0.362
mit(1)15 mitotic 15 0.332
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.327
rap retina aberrant in pattern 0.325
rst roughest 0.317
mib1 mind bomb 1 0.313
skpA CG16983 gene product from transcript CG16983-RD 0.313
mof males absent on the first 0.291
SmD3 Small ribonucleoprotein particle protein SmD3 0.285
gig gigas 0.281
SAK Sak kinase 0.272
numb CG3779 gene product from transcript CG3779-RB 0.270
sws swiss cheese 0.270
morgue modifier of rpr and grim, ubiquitously expressed 0.266
Sce Sex combs extra 0.258
betaTub56D beta-Tubulin at 56D 0.253
mats mob as tumor suppressor 0.238
rok Rho-kinase 0.238
CG13298 CG13298 gene product from transcript CG13298-RA 0.234
dbr debra 0.229
CG32581 CG32581 gene product from transcript CG32581-RB 0.219
Sara Smad anchor for receptor activation 0.219
CG32016 CG32016 gene product from transcript CG32016-RB 0.218
pex10 peroxin 10 0.215
Pros54 Proteasome 54kD subunit 0.204
Taf4 TBP-associated factor 4 0.203
wee CG4488 gene product from transcript CG4488-RA 0.203
Fcp1 CG12252 gene product from transcript CG12252-RA 0.201
Rpn11 CG18174 gene product from transcript CG18174-RA 0.199
Dap160 Dynamin associated protein 160 0.196
tral trailer hitch 0.195
brm brahma 0.193
Atg8a Autophagy-specific gene 8a 0.193
CycJ Cyclin J 0.192
Dad Daughters against dpp 0.184
N Notch 0.183
Ube3a Ubiquitin protein ligase E3A 0.174
casp caspar 0.173
Dcp-1 Death caspase-1 0.172
Zn72D CG5215 gene product from transcript CG5215-RB 0.171
Top1 Topoisomerase 1 0.170
Vhl von Hippel-Lindau 0.168
CG9705 CG9705 gene product from transcript CG9705-RA 0.163
dos daughter of sevenless 0.162
TSG101 tumor suppressor protein 101 0.162
Arr2 Arrestin 2 0.150
CG8232 CG8232 gene product from transcript CG8232-RA 0.149
Uba1 Ubiquitin activating enzyme 1 0.147
Rab7 Rab-protein 7 0.146
Ulp1 CG12359 gene product from transcript CG12359-RA 0.142
drk downstream of receptor kinase 0.141
CG1347 CG1347 gene product from transcript CG1347-RB 0.138
cbx crossbronx 0.138
mle maleless 0.135
Iswi Imitation SWI 0.135
wts warts 0.134
Uev1A CG10640 gene product from transcript CG10640-RA 0.132
MED6 Mediator complex subunit 6 0.130
p53 CG33336 gene product from transcript CG33336-RB 0.130
Psa Puromycin sensitive aminopeptidase 0.129
Mlf Myelodysplasia/myeloid leukemia factor 0.126
hh hedgehog 0.124
tsr twinstar 0.119
Exp6 Exportin 6 0.116
RanGap Ran GTPase activating protein 0.115
Pc Polycomb 0.113
Adar Adenosine deaminase acting on RNA 0.111
Atx2 Ataxin-2 0.110
kuz kuzbanian 0.109
Rab14 Rab-protein 14 0.107
CG6116 CG6116 gene product from transcript CG6116-RA 0.105
chb chromosome bows 0.104
lid little imaginal discs 0.104
CG16721 CG16721 gene product from transcript CG16721-RA 0.104
Smox Smad on X 0.104
Prp8 pre-mRNA processing factor 8 0.103
asf1 anti-silencing factor 1 0.101
bchs blue cheese 0.100
dom domino 0.100
Appl beta amyloid protein precursor-like 0.099
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RNF11 ring finger protein 11 1.000
TP53 tumor protein p53 1.000
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 1.000
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 1.000
UBE2D1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 1.000
TRAF6 TNF receptor-associated factor 6 1.000
UBC ubiquitin C 1.000
XIAP X-linked inhibitor of apoptosis 1.000
UBE2D2 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) 1.000
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.000
RNF5 ring finger protein 5 1.000
UBE2N ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) 1.000
DAXX death-domain associated protein 1.000
UBE3A ubiquitin protein ligase E3A 1.000
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 1.000
CDC27 cell division cycle 27 homolog (S. cerevisiae) 1.000
TRIM39 tripartite motif containing 39 1.000
RNF2 ring finger protein 2 1.000
BMI1 BMI1 polycomb ring finger oncogene 1.000
ANAPC4 anaphase promoting complex subunit 4 1.000
ZNRF1 zinc and ring finger 1 1.000
DTX3L deltex 3-like (Drosophila) 1.000
SMAD2 SMAD family member 2 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
CUL1 cullin 1 1.000
MDM4 Mdm4 p53 binding protein homolog (mouse) 1.000
SKP1 S-phase kinase-associated protein 1 1.000
CDC20 cell division cycle 20 homolog (S. cerevisiae) 1.000
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.999
RING1 ring finger protein 1 0.999
ANAPC5 anaphase promoting complex subunit 5 0.999
SMAD7 SMAD family member 7 0.999
BIRC2 baculoviral IAP repeat containing 2 0.999
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.999
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.999
ARIH2 ariadne homolog 2 (Drosophila) 0.999
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.999
UBE2E1 ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) 0.998
SMAD4 SMAD family member 4 0.998
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.998
BIRC3 baculoviral IAP repeat containing 3 0.998
RAD18 RAD18 homolog (S. cerevisiae) 0.998
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.998
RNF111 ring finger protein 111 0.998
SIAH1 seven in absentia homolog 1 (Drosophila) 0.998
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.997
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.997
CUL3 cullin 3 0.997
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.996
RNF7 ring finger protein 7 0.996
ANAPC7 anaphase promoting complex subunit 7 0.996
CUL5 cullin 5 0.995
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.995
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.995
CDC16 cell division cycle 16 homolog (S. cerevisiae) 0.994
UBE2B ubiquitin-conjugating enzyme E2B (RAD6 homolog) 0.994
MARCH7 membrane-associated ring finger (C3HC4) 7 0.994
CBX8 chromobox homolog 8 0.992
PTEN phosphatase and tensin homolog 0.990
RNF4 ring finger protein 4 0.989
PCGF2 polycomb group ring finger 2 0.989
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.988
SMAD3 SMAD family member 3 0.988
USP11 ubiquitin specific peptidase 11 0.988
RNF14 ring finger protein 14 0.987
TRIM8 tripartite motif containing 8 0.987
SFN stratifin 0.986
ANAPC11 anaphase promoting complex subunit 11 0.985
TRAF3 TNF receptor-associated factor 3 0.984
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.981
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.981
DZIP3 DAZ interacting protein 3, zinc finger 0.980
TRIM43 tripartite motif containing 43 0.980
VCP valosin containing protein 0.980
TRIM27 tripartite motif containing 27 0.979
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.978
UBE2H ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) 0.977
CHFR checkpoint with forkhead and ring finger domains 0.976
ANAPC1 anaphase promoting complex subunit 1 0.975
RNF126 ring finger protein 126 0.974
FBXO5 F-box protein 5 0.974
RNF38 ring finger protein 38 0.973
ARIH1 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) 0.971
CUL2 cullin 2 0.966
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.964
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.963
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 0.960
MKRN1 makorin ring finger protein 1 0.960
CDC23 cell division cycle 23 homolog (S. cerevisiae) 0.955
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.954
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.950
CSNK1A1 casein kinase 1, alpha 1 0.948
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) 0.948
PIAS4 protein inhibitor of activated STAT, 4 0.947
MARCH5 membrane-associated ring finger (C3HC4) 5 0.944
UBE2W ubiquitin-conjugating enzyme E2W (putative) 0.940
OTUB1 OTU domain, ubiquitin aldehyde binding 1 0.940
BCOR BCL6 corepressor 0.940
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.938
RNF114 ring finger protein 114 0.936
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Rnf2 ring finger protein 2 1.000
Mdm2 transformed mouse 3T3 cell double minute 2 0.997
Trp53 transformation related protein 53 0.989
Vcp valosin containing protein 0.984
Cry2 cryptochrome 2 (photolyase-like) 0.953
Per2 period homolog 2 (Drosophila) 0.943
Pcgf2 polycomb group ring finger 2 0.940
Trim30a tripartite motif-containing 30A 0.925
Sharpin SHANK-associated RH domain interacting protein 0.904
Ncoa3 nuclear receptor coactivator 3 0.904
Mdm4 transformed mouse 3T3 cell double minute 4 0.899
Rybp RING1 and YY1 binding protein 0.893
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.859
Daxx Fas death domain-associated protein 0.858
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.851
Bmi1 Bmi1 polycomb ring finger oncogene 0.828
Tcf3 transcription factor 3 0.813
Apc adenomatosis polyposis coli 0.810
Pparg peroxisome proliferator activated receptor gamma 0.810
Kdm2b lysine (K)-specific demethylase 2B 0.807
Stat1 signal transducer and activator of transcription 1 0.777
Ikbkb inhibitor of kappaB kinase beta 0.771
Clock circadian locomotor output cycles kaput 0.765
Ikbkg inhibitor of kappaB kinase gamma 0.763
Skil SKI-like 0.746
Phc2 polyhomeotic-like 2 (Drosophila) 0.723
Ncstn nicastrin 0.717
Cand1 cullin associated and neddylation disassociated 1 0.717
Oasl2 2'-5' oligoadenylate synthetase-like 2 0.712
Gbp7 guanylate binding protein 7 0.709
Skp1a S-phase kinase-associated protein 1A 0.702
Cul4a cullin 4A 0.701
Sqstm1 sequestosome 1 0.694
Usp18 ubiquitin specific peptidase 18 0.681
Irf9 interferon regulatory factor 9 0.680
Traf6 TNF receptor-associated factor 6 0.673
Shh sonic hedgehog 0.670
Casp1 caspase 1 0.663
Per1 period homolog 1 (Drosophila) 0.615
Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 0.597
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.596
Rabep1 rabaptin, RAB GTPase binding effector protein 1 0.594
Setdb1 SET domain, bifurcated 1 0.593
Axin1 axin 1 0.593
Trim21 tripartite motif-containing 21 0.590
Ubap1 ubiquitin-associated protein 1 0.588
Ccndbp1 cyclin D-type binding-protein 1 0.582
En1 engrailed 1 0.581
Notch2 Notch gene homolog 2 (Drosophila) 0.576
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.572
Aamp angio-associated migratory protein 0.571
Neurod1 neurogenic differentiation 1 0.567
Atf4 activating transcription factor 4 0.544
Ube2l3 ubiquitin-conjugating enzyme E2L 3 0.543
Cbx7 chromobox homolog 7 0.536
Hipk1 homeodomain interacting protein kinase 1 0.535
Rsad2 radical S-adenosyl methionine domain containing 2 0.531
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.522
Rnf111 ring finger 111 0.515
Nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 0.514
Ctnnb1 catenin (cadherin associated protein), beta 1 0.506
Ring1 ring finger protein 1 0.497
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.496
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.485
Map2k4 mitogen-activated protein kinase kinase 4 0.483
Arnt aryl hydrocarbon receptor nuclear translocator 0.480
Matr3 matrin 3 0.477
Trp73 transformation related protein 73 0.477
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.475
Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.474
Kl klotho 0.473
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.469
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.468
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.467
ND6 NADH dehydrogenase subunit 6 0.465
Mapk8 mitogen-activated protein kinase 8 0.464
Gclm glutamate-cysteine ligase, modifier subunit 0.461
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.460
Ap1g1 adaptor protein complex AP-1, gamma 1 subunit 0.452
Ldb3 LIM domain binding 3 0.450
Vhl von Hippel-Lindau tumor suppressor 0.449
Egr2 early growth response 2 0.445
Smad6 MAD homolog 6 (Drosophila) 0.439
Banf1 barrier to autointegration factor 1 0.438
Irf7 interferon regulatory factor 7 0.438
Traf3 TNF receptor-associated factor 3 0.437
Uba7 ubiquitin-like modifier activating enzyme 7 0.437
Usp8 ubiquitin specific peptidase 8 0.436
Rnf41 ring finger protein 41 0.436
Trp63 transformation related protein 63 0.431
Rnf11 ring finger protein 11 0.428
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.425
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.418
Bap1 Brca1 associated protein 1 0.417
Trp53bp1 transformation related protein 53 binding protein 1 0.413
Phf1 PHD finger protein 1 0.413
Wnt3a wingless-related MMTV integration site 3A 0.410
Irf1 interferon regulatory factor 1 0.409
Cyld cylindromatosis (turban tumor syndrome) 0.407
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans) 0.404
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Dctn4 dynactin 4 0.709
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.336
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.206
Canx calnexin 0.097
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.095
Csnk1d casein kinase 1, delta 0.083
Taok1 TAO kinase 1 0.078
Hsph1 heat shock 105/110 protein 1 0.077
Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 0.071
Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.068
Tollip toll interacting protein 0.068
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.068
Ubc ubiquitin C 0.067
Zfand5 zinc finger, AN1-type domain 5 0.059
Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform 0.056
Nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 0.055
Pex13 peroxisomal biogenesis factor 13 0.052
Tspyl1 TSPY-like 1 0.043
Hprt1 hypoxanthine phosphoribosyltransferase 1 0.043
Dnm1l dynamin 1-like 0.042
Zfp364 zinc finger protein 364 0.040
Adam10 ADAM metallopeptidase domain 10 0.038
Cfl2 cofilin 2, muscle 0.038
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.037
MGC105560 similar to Hypothetical protein BC014729 0.036
Psmb3 proteasome (prosome, macropain) subunit, beta type 3 0.035
Vapa VAMP (vesicle-associated membrane protein)-associated protein A 0.034
Tjp1 tight junction protein 1 0.034
Eif4h eukaryotic translation initiation factor 4H 0.033
Prkar1a protein kinase, cAMP-dependent, regulatory, type I, alpha 0.032
Rnf138 ring finger protein 138 0.032
Senp2 Sumo1/sentrin/SMT3 specific peptidase 2 0.032
Psmb4 proteasome (prosome, macropain) subunit, beta type 4 0.031
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.031
Dazap2 DAZ associated protein 2 0.030
Adrbk1 adrenergic, beta, receptor kinase 1 0.030
Tbpl1 TATA box binding protein-like 1 0.030
Troap trophinin associated protein 0.029
Maoa monoamine oxidase A 0.029
Rabep2 rabaptin, RAB GTPase binding effector protein 2 0.029
Actr6 ARP6 actin-related protein 6 homolog (yeast) 0.028
Mapk1 mitogen activated protein kinase 1 0.028
Rfc1 replication factor C (activator 1) 1 0.028
Rbm18 RNA binding motif protein 18 0.028
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.027
Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 0.027
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.027
Nckap1 NCK-associated protein 1 0.027
Paip1 poly(A) binding protein interacting protein 1 0.027
Mgea5 meningioma expressed antigen 5 (hyaluronidase) 0.027
Atf2 activating transcription factor 2 0.027
Cops2 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) 0.027
Ctdp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.027
Txnl1 thioredoxin-like 1 0.026
Spcs1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 0.026
Wdr5 WD repeat domain 5 0.026
Ppp2r5e protein phosphatase 2, regulatory subunit B', epsilon isoform 0.026
Zranb2 zinc finger, RAN-binding domain containing 2 0.026
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.026
Magt1 magnesium transporter 1 0.025
Mprip myosin phosphatase Rho interacting protein 0.025
Snx16 sorting nexin 16 0.024
Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.024
Eef2 eukaryotic translation elongation factor 2 0.024
Trdmt1 tRNA aspartic acid methyltransferase 1 0.024
Trappc10 trafficking protein particle complex 10 0.024
Fundc1 FUN14 domain containing 1 0.024
Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 0.023
Dync1i2 dynein cytoplasmic 1 intermediate chain 2 0.023
Exoc5 exocyst complex component 5 0.023
Ppp2cb protein phosphatase 2, catalytic subunit, beta isoform 0.023
Dnpep aspartyl aminopeptidase 0.023
RT1-EC2 RT1 class Ib, locus EC2 0.023
Tagln3 transgelin 3 0.023
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.023
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.023
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.023
Golph3 golgi phosphoprotein 3 (coat-protein) 0.023
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.022
Matk megakaryocyte-associated tyrosine kinase 0.022
Lin7c lin-7 homolog C (C. elegans) 0.022
Rb1 retinoblastoma 1 0.022
Hbxip hepatitis B virus x interacting protein 0.021
Tomm70a translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 0.021
Ube2e3 ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog (yeast) 0.021
Pja2 praja 2, RING-H2 motif containing 0.021
Rab21 RAB21, member RAS oncogene family 0.021
Rnf2 ring finger protein 2 0.021
Men1 multiple endocrine neoplasia 1 0.021
Ampd1 adenosine monophosphate deaminase 1 (isoform M) 0.021
Clns1a chloride channel, nucleotide-sensitive, 1A 0.020
Sirt2 sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) 0.020
LOC100363783 rCG53773-like 0.020
Actr1a ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.020
Fam174a family with sequence similarity 174, member A 0.020
Cugbp1 CUG triplet repeat, RNA binding protein 1 0.019
Tpd52 tumor protein D52 0.019
LOC100366237 prefoldin subunit 4-like 0.019
Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.019
Atp6v1b2 ATPase, H transporting, lysosomal V1 subunit B2 0.019