The network for 'regulation of cell cycle phase transition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cell cycle phase transition

Any process that modulates the frequency, rate or extent of cell cycle phase transition.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
KEL1 Kel1p 0.916
GLC7 Glc7p 0.848
BUB3 Bub3p 0.847
CDC14 Cdc14p 0.722
CDC55 Cdc55p 0.686
ZDS2 Zds2p 0.685
CDC28 Cdc28p 0.548
SPT16 Spt16p 0.461
MAD2 Mad2p 0.460
GIC1 Gic1p 0.449
PPH22 Pph22p 0.412
RTS1 Rts1p 0.353
RAD53 Rad53p 0.341
CDC16 Cdc16p 0.319
MCM10 Mcm10p 0.280
PDS1 Pds1p 0.276
CLB5 Clb5p 0.276
RPO26 Rpo26p 0.266
DBF4 Dbf4p 0.259
SRS2 Srs2p 0.259
PPH21 Pph21p 0.242
SPT5 Spt5p 0.241
RAD50 Rad50p 0.232
RTT107 Rtt107p 0.224
SLK19 Slk19p 0.219
CDC20 Cdc20p 0.212
SPC110 Spc110p 0.211
RAD24 Rad24p 0.205
DPB2 Dpb2p 0.200
CSE4 Cse4p 0.193
IML3 Iml3p 0.190
DMA2 Dma2p 0.187
RFA1 Rfa1p 0.185
SLD3 Sld3p 0.178
NBL1 Nbl1p 0.176
CDC25 Cdc25p 0.171
DOC1 Doc1p 0.171
SMC4 Smc4p 0.170
CDC26 Cdc26p 0.167
BFA1 Bfa1p 0.166
GIN4 Gin4p 0.160
CLB4 Clb4p 0.159
CLB6 Clb6p 0.154
HTA1 Hta1p 0.154
CLB3 Clb3p 0.153
CLB2 Clb2p 0.151
MTW1 Mtw1p 0.144
RCO1 Rco1p 0.141
CBF2 Cbf2p 0.141
BUB1 Bub1p 0.138
PLC1 Plc1p 0.134
CDC23 Cdc23p 0.131
RAD9 Rad9p 0.131
NFI1 Nfi1p 0.127
NSL1 Nsl1p 0.126
MAD3 Mad3p 0.125
TFG1 Tfg1p 0.123
CTF4 Ctf4p 0.123
FMP48 Fmp48p 0.122
KEL2 Kel2p 0.121
ASE1 Ase1p 0.121
PSF2 Psf2p 0.119
CDC27 Cdc27p 0.119
EAF1 Eaf1p 0.117
BCK1 Bck1p 0.116
MCM5 Mcm5p 0.113
CTF13 Ctf13p 0.112
RRM3 Rrm3p 0.110
MEC1 Mec1p 0.103
CHL4 Chl4p 0.103
SCC2 Scc2p 0.102
PEX22 Pex22p 0.100
FAR1 Far1p 0.099
RPB3 Rpb3p 0.098
SLG1 Slg1p 0.097
PSP2 Psp2p 0.097
POL30 Pol30p 0.096
BMH1 Bmh1p 0.096
BIM1 Bim1p 0.095
MCM21 Mcm21p 0.094
RSC1 Rsc1p 0.094
MCM6 Mcm6p 0.093
CTF19 Ctf19p 0.092
SIC1 Sic1p 0.092
KAP95 Kap95p 0.092
TPD3 Tpd3p 0.091
SMC6 Smc6p 0.091
WHI2 Whi2p 0.090
KIN1 Kin1p 0.090
NKP2 Nkp2p 0.089
PIG2 Pig2p 0.089
CKS1 Cks1p 0.088
SLI15 Sli15p 0.088
CDC40 Cdc40p 0.086
ARP9 Arp9p 0.086
TAF14 Taf14p 0.084
ZIP1 Zip1p 0.084
GAC1 Gac1p 0.083
CKA1 Cka1p 0.083
SET1 Set1p 0.083
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.079
rnr-1 Protein RNR-1 0.072
bub-1 Protein BUB-1 0.063
csn-3 Protein CSN-3 0.046
mat-3 Protein MAT-3 0.036
hcf-1 Protein HCF-1 0.033
dsh-2 Protein DSH-2 0.032
CELE_C24H12.5 Protein C24H12.5 0.030
egl-30 Protein EGL-30 0.030
mel-28 Protein MEL-28 0.030
hcp-6 Protein HCP-6 0.029
npp-16 Protein NPP-16 0.029
fox-1 Protein FOX-1 0.027
npp-15 Protein NPP-15 0.027
C05C10.2 Protein C05C10.2 0.024
R05D3.2 Protein R05D3.2 0.024
cul-2 Protein CUL-2 0.024
sel-8 Protein SEL-8 0.023
rpa-1 Protein RPA-1 0.023
sel-12 Protein SEL-12 0.023
ZK632.5 Protein ZK632.5 0.023
cyb-2.1 Protein CYB-2.1 0.022
pry-1 Protein PRY-1 0.022
spd-1 Protein SPD-1 0.020
mex-3 Protein MEX-3 0.020
brc-1 Protein BRC-1 0.019
F12F6.1 Protein F12F6.1 0.019
klp-19 Protein KLP-19 0.018
mcm-5 Protein MCM-5 0.018
lig-1 Protein LIG-1 0.017
csn-5 Protein CSN-5 0.016
gad-1 Protein GAD-1 0.016
trr-1 Protein TRR-1 0.016
dpl-1 Protein DPL-1 0.016
gei-4 Protein GEI-4 0.016
csn-1 Protein CSN-1 0.016
xpo-1 Protein XPO-1 0.015
attf-2 Protein ATTF-2 0.015
sas-5 Protein SAS-5 0.015
pha-4 Protein PHA-4 0.015
ima-2 Protein IMA-2 0.015
him-10 Protein HIM-10 0.015
eor-1 Protein EOR-1 0.015
asd-1 Protein ASD-1 0.014
hpo-9 Protein HPO-9 0.014
zyg-9 Protein ZYG-9 0.014
ect-2 Protein ECT-2 0.014
srgp-1 Protein SRGP-1 0.014
F08B4.7 Protein F08B4.7 0.014
mcm-2 Protein MCM-2 0.014
tag-307 Protein TAG-307 0.014
swsn-7 Protein SWSN-7 0.013
cyk-4 Protein CYK-4 0.013
rps-15 Protein RPS-15 0.013
mcm-7 Protein MCM-7 0.013
cdt-1 Protein CDT-1 0.013
lst-1 Protein LST-1 0.013
lag-2 Protein LAG-2 0.013
lin-9 Protein LIN-9 0.013
cash-1 Protein CASH-1 0.013
thoc-2 Protein THOC-2 0.013
npp-21 Protein NPP-21 0.013
toca-2 Protein TOCA-2 0.013
sma-6 Protein SMA-6 0.013
cin-4 Protein CIN-4 0.012
nrde-1 Protein NRDE-1 0.012
hpo-10 Protein HPO-10 0.012
gld-1 Protein GLD-1 0.012
isw-1 Protein ISW-1 0.012
top-2 Protein TOP-2 0.012
tim-1 Protein TIM-1 0.012
cand-1 Protein CAND-1 0.012
npp-12 Protein NPP-12 0.012
gpd-4 Protein GPD-4 0.012
ZK1055.7 Protein ZK1055.7 0.012
pch-2 Protein PCH-2 0.011
wrm-1 Protein WRM-1 0.011
flh-1 Protein FLH-1 0.011
eya-1 Protein EYA-1 0.011
CELE_F59A6.5 Protein F59A6.5 0.011
ucr-2.3 Protein UCR-2.3 0.011
F49C12.9 Protein F49C12.9 0.010
D1044.6 Protein D1044.6 0.010
dna-2 Protein DNA-2 0.010
D1081.8 Protein D1081.8 0.010
mom-2 Protein MOM-2 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ccnb1 cyclin B1 0.412
dtl denticleless homolog (Drosophila) 0.164
zff9 zinc finger protein 9 0.122
kif23 kinesin family member 23 0.101
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.079
ncapg non-SMC condensin I complex, subunit G 0.069
id1 inhibitor of DNA binding 1 0.068
si:ch211-215h6.2 si:ch211-215h6.2 0.057
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.057
cul3a cullin 3a 0.055
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.055
nup107 nucleoporin 107 0.052
top2a topoisomerase (DNA) II alpha 0.049
ccna2 cyclin A2 0.048
plk1 polo-like kinase 1 (Drosophila) 0.046
mapk3 mitogen-activated protein kinase 3 0.045
hdac3 histone deacetylase 3 0.045
ccnd1 cyclin D1 0.042
efnb2a ephrin B2a 0.042
slbp stem-loop binding protein 0.042
msh6 mutS homolog 6 (E. coli) 0.041
skp2 S-phase kinase-associated protein 2 (p45) 0.039
anxa1a annexin A1a 0.037
mitfa microphthalmia-associated transcription factor a 0.037
prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.035
arhgap11a Rho GTPase activating protein 11A 0.035
orc1 origin recognition complex, subunit 1 0.034
anxa1b annexin A1b 0.034
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.034
alcama activated leukocyte cell adhesion molecule a 0.033
nasp nuclear autoantigenic sperm protein (histone-binding) 0.033
oep one-eyed pinhead 0.032
sass6 spindle assembly 6 homolog (C. elegans) 0.032
smo smoothened homolog (Drosophila) 0.032
dusp1 dual specificity phosphatase 1 0.031
si:ch211-244o22.2 si:ch211-244o22.2 0.030
mmp2 matrix metalloproteinase 2 0.030
cdt1 chromatin licensing and DNA replication factor 1 0.029
srsf1a serine/arginine-rich splicing factor 1a 0.027
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.026
pcna proliferating cell nuclear antigen 0.026
smad1 MAD homolog 1 (Drosophila) 0.026
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.026
ncapd2 non-SMC condensin I complex, subunit D2 0.026
zgc:101661 zgc:101661 0.025
mab21l1 mab-21-like 1 0.024
rqcd1 RCD1 required for cell differentiation1 homolog (S. pombe) 0.023
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.023
ccnb2 cyclin B2 0.023
cdh2 cadherin 2, neuronal 0.023
rtkn2 rhotekin 2 0.023
ddb2 damage-specific DNA binding protein 2 0.022
dcun1d5 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) 0.022
sap18 sin3-associated polypeptide 0.022
caprin1a cell cycle associated protein 1a 0.021
tgif1 TGFB-induced factor homeobox 1 0.021
krt5 keratin 5 0.021
map2k4a mitogen-activated protein kinase kinase 4a 0.021
ube2i2 ubiquitin-conjugating enzyme E2I2 0.020
gmnn geminin, DNA replication inhibitor 0.020
aurkb aurora kinase B 0.019
her6 hairy-related 6 0.019
rnf40 ring finger protein 40 0.019
atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.019
rpl23 ribosomal protein L23 0.019
cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 0.019
tbc1d23 TBC1 domain family, member 23 0.019
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.019
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.019
cand1 cullin-associated and neddylation-dissociated 1 0.019
spock3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.019
aplp2 amyloid beta (A4) precursor-like protein 2 0.019
zgc:103670 zgc:103670 0.018
tardbpl TAR DNA binding protein, like 0.018
gro2 groucho 2 0.018
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.018
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.018
ncor1 nuclear receptor co-repressor 1 0.017
smc2 structural maintenance of chromosomes 2 0.017
htatsf1 HIV TAT specific factor 1 0.017
zgc:174506 zgc:174506 0.017
arl4ab ADP-ribosylation factor-like 4ab 0.017
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.017
cops3 COP9 constitutive photomorphogenic homolog subunit 3 0.017
kif14 kinesin family member 14 0.017
trip13 thyroid hormone receptor interactor 13 0.017
gro1 groucho 1 0.017
ppp4r2a protein phosphatase 4, regulatory subunit 2a 0.016
irf6 interferon regulatory factor 6 0.016
rltpr RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing 0.016
fam158a family with sequence similarity 158, member A 0.016
smarcb1a SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a 0.016
cdc20 cell division cycle 20 homolog 0.016
smc4 structural maintenance of chromosomes 4 0.016
cav1 caveolin 1 0.016
axin1 axin 1 0.016
senp3a SUMO1/sentrin/SMT3 specific peptidase 3a 0.015
pbrm1l polybromo 1, like 0.015
matr3l matrin 3-like 0.015
paf1 paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.015
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pp1-87B Protein phosphatase 1 at 87B 0.998
tefu telomere fusion 0.996
dap dacapo 0.990
skpA CG16983 gene product from transcript CG16983-RD 0.967
brm brahma 0.948
Akt1 CG4006 gene product from transcript CG4006-RA 0.944
p53 CG33336 gene product from transcript CG33336-RB 0.936
polo CG12306 gene product from transcript CG12306-RA 0.933
Cp190 Centrosomal protein 190kD 0.925
phl pole hole 0.912
CSN5 COP9 complex homolog subunit 5 0.911
Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein 0.895
Iswi Imitation SWI 0.895
Cdc37 CG12019 gene product from transcript CG12019-RA 0.876
pic piccolo 0.847
Rpd3 CG7471 gene product from transcript CG7471-RA 0.837
gro groucho 0.827
rux roughex 0.819
lok loki 0.800
cdc2 CG5363 gene product from transcript CG5363-RA 0.798
MED6 Mediator complex subunit 6 0.786
hyd hyperplastic discs 0.771
mei-9 meiotic 9 0.767
His2Av Histone H2A variant 0.742
cnn centrosomin 0.730
ash2 absent, small, or homeotic discs 2 0.724
Bj1 Bj1 protein 0.719
Grip84 gamma-tubulin ring protein 84 0.715
Det Deterin 0.711
east enhanced adult sensory threshold 0.700
lds lodestar 0.697
Mad Mothers against dpp 0.678
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.660
BubR1 Bub1-related kinase 0.651
Gug Grunge 0.641
Brca2 Breast cancer 2, early onset homolog 0.640
lin19 lin-19-like 0.637
CtBP C-terminal Binding Protein 0.636
ctp cut up 0.630
asp abnormal spindle 0.627
spn-B spindle B 0.619
Nup358 Nucleoporin 358 0.615
Cdk4 Cyclin-dependent kinase 4 0.608
Axn Axin 0.608
CycE Cyclin E 0.607
numb CG3779 gene product from transcript CG3779-RB 0.604
rept reptin 0.594
SF2 CG6987 gene product from transcript CG6987-RA 0.584
Top1 Topoisomerase 1 0.583
mus304 mutagen-sensitive 304 0.576
cdc16 CG6759 gene product from transcript CG6759-RA 0.573
SAK Sak kinase 0.564
fzy fizzy 0.562
Klp10A CG1453 gene product from transcript CG1453-RA 0.541
nbs CG6754 gene product from transcript CG6754-RC 0.539
okr okra 0.535
wee CG4488 gene product from transcript CG4488-RA 0.529
CycB3 Cyclin B3 0.522
MAGE CG10059 gene product from transcript CG10059-RA 0.515
Klp3A Kinesin-like protein at 3A 0.507
Hdac3 Histone deacetylase 3 0.500
E(z) Enhancer of zeste 0.491
tws twins 0.491
Egfr Epidermal growth factor receptor 0.489
mre11 meiotic recombination 11 0.489
rad50 CG6339 gene product from transcript CG6339-RD 0.480
CSN6 COP9 complex homolog subunit 6 0.479
endos endosulfine 0.479
Dhc64C Dynein heavy chain 64C 0.471
Cap-G CG34438 gene product from transcript CG34438-RF 0.470
mus205 mutagen-sensitive 205 0.470
mus301 mutagen-sensitive 301 0.465
orb oo18 RNA-binding protein 0.464
CSN3 COP9 complex homolog subunit 3 0.457
shn schnurri 0.457
CycB Cyclin B 0.450
Kmn1 kinetochore Mis12-Ndc80 network component 1 0.448
Dref DNA replication-related element factor 0.434
dco discs overgrown 0.426
glu gluon 0.425
dmt dalmatian 0.407
Chc Clathrin heavy chain 0.407
rap retina aberrant in pattern 0.406
mei-41 meiotic 41 0.406
sxc super sex combs 0.405
Rbf Retinoblastoma-family protein 0.404
Su(var)205 Suppressor of variegation 205 0.400
cdm cadmus 0.394
borr borealin-related 0.386
ik2 IkappaB kinase-like 2 0.383
ftz-f1 ftz transcription factor 1 0.376
emb embargoed 0.375
hbs hibris 0.374
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.373
RanGap Ran GTPase activating protein 0.370
alphaTub67C alpha-Tubulin at 67C 0.359
RpS3A Ribosomal protein S3A 0.355
nej nejire 0.352
mad2 CG17498 gene product from transcript CG17498-RA 0.350
G-oalpha47A G protein oalpha 47A 0.343
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RB1 retinoblastoma 1 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 1.000
CDK2 cyclin-dependent kinase 2 0.999
TP53 tumor protein p53 0.998
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.998
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.994
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.992
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.987
BRCA1 breast cancer 1, early onset 0.987
CUL1 cullin 1 0.986
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.986
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.979
H2AFX H2A histone family, member X 0.974
CUL2 cullin 2 0.971
NOTCH1 notch 1 0.954
CDK8 cyclin-dependent kinase 8 0.948
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.926
RBL2 retinoblastoma-like 2 (p130) 0.919
CCND1 cyclin D1 0.916
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.909
BCL2 B-cell CLL/lymphoma 2 0.901
HDAC2 histone deacetylase 2 0.901
SKP1 S-phase kinase-associated protein 1 0.882
E2F1 E2F transcription factor 1 0.875
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.865
XIAP X-linked inhibitor of apoptosis 0.860
CCNA2 cyclin A2 0.859
BRCA2 breast cancer 2, early onset 0.858
CCNB1 cyclin B1 0.856
SKP2 S-phase kinase-associated protein 2 (p45) 0.851
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.837
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.821
TFDP1 transcription factor Dp-1 0.814
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.807
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.805
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.802
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.798
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.791
MED1 mediator complex subunit 1 0.789
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.784
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.777
HDAC1 histone deacetylase 1 0.756
BTRC beta-transducin repeat containing 0.744
CLSPN claspin 0.742
CDC25A cell division cycle 25 homolog A (S. pombe) 0.727
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.723
E2F4 E2F transcription factor 4, p107/p130-binding 0.708
SMC6 structural maintenance of chromosomes 6 0.706
ANAPC4 anaphase promoting complex subunit 4 0.702
PLK1 polo-like kinase 1 0.698
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.678
CCND3 cyclin D3 0.678
MDC1 mediator of DNA-damage checkpoint 1 0.667
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.664
RBBP8 retinoblastoma binding protein 8 0.663
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.638
BLM Bloom syndrome, RecQ helicase-like 0.633
RAD50 RAD50 homolog (S. cerevisiae) 0.625
RBL1 retinoblastoma-like 1 (p107) 0.623
CDK6 cyclin-dependent kinase 6 0.621
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.618
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.609
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.586
COPS8 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) 0.582
MSH6 mutS homolog 6 (E. coli) 0.571
COPS3 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) 0.568
LIN9 lin-9 homolog (C. elegans) 0.560
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.553
ANAPC1 anaphase promoting complex subunit 1 0.552
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.551
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.551
VHL von Hippel-Lindau tumor suppressor 0.546
DAXX death-domain associated protein 0.538
PCNA proliferating cell nuclear antigen 0.537
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.527
TOP2A topoisomerase (DNA) II alpha 170kDa 0.517
JAG1 jagged 1 0.517
PKM2 pyruvate kinase, muscle 0.506
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) 0.503
SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 0.503
ATM ataxia telangiectasia mutated 0.500
CHD4 chromodomain helicase DNA binding protein 4 0.492
RAD1 RAD1 homolog (S. pombe) 0.481
TOP1 topoisomerase (DNA) I 0.480
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.461
IER3 immediate early response 3 0.443
FOXM1 forkhead box M1 0.440
ARID1A AT rich interactive domain 1A (SWI-like) 0.434
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.425
FADD Fas (TNFRSF6)-associated via death domain 0.423
CCNE1 cyclin E1 0.423
C19orf39 chromosome 19 open reading frame 39 0.421
DTL denticleless homolog (Drosophila) 0.418
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.416
UBE3A ubiquitin protein ligase E3A 0.408
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.403
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.386
MYBL2 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 0.384
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.357
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.357
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Rb1 retinoblastoma 1 0.995
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.987
E2f1 E2F transcription factor 1 0.978
Pten phosphatase and tensin homolog 0.963
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.944
Brca2 breast cancer 2 0.937
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.935
Notch1 Notch gene homolog 1 (Drosophila) 0.920
Brca1 breast cancer 1 0.891
Pou5f1 POU domain, class 5, transcription factor 1 0.886
Smad4 MAD homolog 4 (Drosophila) 0.863
Mdm2 transformed mouse 3T3 cell double minute 2 0.857
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.807
Ctnnb1 catenin (cadherin associated protein), beta 1 0.802
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.767
Rbl1 retinoblastoma-like 1 (p107) 0.734
Msh2 mutS homolog 2 (E. coli) 0.716
Bax BCL2-associated X protein 0.707
Ccne1 cyclin E1 0.703
Cdk4 cyclin-dependent kinase 4 0.638
Bcl2 B-cell leukemia/lymphoma 2 0.583
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.574
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.565
Shh sonic hedgehog 0.559
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.556
Set SET nuclear oncogene 0.528
Pax6 paired box gene 6 0.525
Skil SKI-like 0.525
Mdm4 transformed mouse 3T3 cell double minute 4 0.514
Cdk1 cyclin-dependent kinase 1 0.507
Nbn nibrin 0.485
Psen1 presenilin 1 0.485
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.484
Pcna proliferating cell nuclear antigen 0.482
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.469
Nf1 neurofibromatosis 1 0.458
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.453
Arid1b AT rich interactive domain 1B (SWI-like) 0.451
Dtl denticleless homolog (Drosophila) 0.444
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.429
Tcfcp2l1 transcription factor CP2-like 1 0.420
Mybl2 myeloblastosis oncogene-like 2 0.393
Sox2 SRY-box containing gene 2 0.382
Nde1 nuclear distribution gene E homolog 1 (A nidulans) 0.367
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.351
Pax3 paired box gene 3 0.345
Ccnf cyclin F 0.323
Gli2 GLI-Kruppel family member GLI2 0.318
Mis18bp1 MIS18 binding protein 1 0.313
Gli3 GLI-Kruppel family member GLI3 0.312
Rara retinoic acid receptor, alpha 0.312
Plk1 polo-like kinase 1 (Drosophila) 0.308
Kit kit oncogene 0.299
Chd4 chromodomain helicase DNA binding protein 4 0.299
Cenpk centromere protein K 0.297
Orc1 origin recognition complex, subunit 1 0.296
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.291
Usp1 ubiquitin specific peptidase 1 0.287
C330027C09Rik RIKEN cDNA C330027C09 gene 0.280
Tcf3 transcription factor 3 0.280
Prnp prion protein 0.276
Esrrb estrogen related receptor, beta 0.275
Arid1a AT rich interactive domain 1A (SWI-like) 0.269
Trim28 tripartite motif-containing 28 0.269
Ccnb1 cyclin B1 0.263
Cdk2 cyclin-dependent kinase 2 0.260
Sall4 sal-like 4 (Drosophila) 0.252
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.243
Kat2a K(lysine) acetyltransferase 2A 0.238
Lig1 ligase I, DNA, ATP-dependent 0.230
Chek1 checkpoint kinase 1 homolog (S. pombe) 0.227
Ccnd1 cyclin D1 0.226
Fgfr2 fibroblast growth factor receptor 2 0.225
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.224
Aurka aurora kinase A 0.223
Cdc25a cell division cycle 25 homolog A (S. pombe) 0.220
Gpi1 glucose phosphate isomerase 1 0.218
Ret ret proto-oncogene 0.215
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.210
Ncapd2 non-SMC condensin I complex, subunit D2 0.208
Birc5 baculoviral IAP repeat-containing 5 0.208
Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.198
Cdt1 chromatin licensing and DNA replication factor 1 0.195
Ptch1 patched homolog 1 0.194
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.191
Klf5 Kruppel-like factor 5 0.190
Mbd3 methyl-CpG binding domain protein 3 0.185
Zfp362 zinc finger protein 362 0.184
Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.183
Sp1 trans-acting transcription factor 1 0.183
Pax2 paired box gene 2 0.181
Mta1 metastasis associated 1 0.178
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.178
Numa1 nuclear mitotic apparatus protein 1 0.176
Braf Braf transforming gene 0.175
Tcf19 transcription factor 19 0.174
Notch2 Notch gene homolog 2 (Drosophila) 0.174
Kif11 kinesin family member 11 0.173
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.173
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Top2a topoisomerase (DNA) II alpha 0.094
Pcna proliferating cell nuclear antigen 0.092
Racgap1 Rac GTPase-activating protein 1 0.065
March8 membrane-associated ring finger (C3HC4) 8 0.040
Tollip toll interacting protein 0.038
Rnps1 ribonucleic acid binding protein S1 0.036
Cdk4 cyclin-dependent kinase 4 0.033
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.032
Mcm5 minichromosome maintenance complex component 5 0.027
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.026
Lmnb1 lamin B1 0.025
Hist1h1a histone cluster 1, H1a 0.023
Pkm2 pyruvate kinase, muscle 0.023
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.022
Taok1 TAO kinase 1 0.021
Usf2 upstream transcription factor 2, c-fos interacting 0.021
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.020
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.020
Ccnd3 cyclin D3 0.019
Dlg4 discs, large homolog 4 (Drosophila) 0.018
Cops2 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) 0.018
Homer1 homer homolog 1 (Drosophila) 0.018
Usp9x ubiquitin specific peptidase 9, X-linked 0.017
Tubg1 tubulin, gamma 1 0.017
Git1 G protein-coupled receptor kinase interacting ArfGAP 1 0.017
Rrm2 ribonucleotide reductase M2 0.017
Cdk2 cyclin dependent kinase 2 0.017
Phax phosphorylated adaptor for RNA export 0.016
Smad4 SMAD family member 4 0.016
Ubtf upstream binding transcription factor, RNA polymerase I 0.016
Rb1 retinoblastoma 1 0.016
Rara retinoic acid receptor, alpha 0.015
Cd37 CD37 molecule 0.015
Tcp11l2 t-complex 11 (mouse) like 2 0.015
Drd1a dopamine receptor D1A 0.015
Arhgap1 Rho GTPase activating protein 1 0.014
Fgfr1 Fibroblast growth factor receptor 1 0.014
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.014
Arpc5 actin related protein 2/3 complex, subunit 5 0.014
Zfand5 zinc finger, AN1-type domain 5 0.013
Gcs1 glucosidase 1 0.013
Ppara peroxisome proliferator activated receptor alpha 0.013
Pde5a phosphodiesterase 5A, cGMP-specific 0.013
Eif4h eukaryotic translation initiation factor 4H 0.013
Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 0.012
Ccnd1 cyclin D1 0.012
Add1 adducin 1 (alpha) 0.012
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.011
Il18 interleukin 18 0.011
Lsm14a LSM14A, SCD6 homolog A (S. cerevisiae) 0.011
Kif2c kinesin family member 2C 0.011
Slfn2 schlafen 2 0.011
Parp1 poly (ADP-ribose) polymerase 1 0.011
Foxi2 forkhead box I2 0.011
Zfp364 zinc finger protein 364 0.010
Prkcb protein kinase C, beta 0.010
Kif22 kinesin family member 22 0.010
Cdca7 cell division cycle associated 7 0.010
Nasp nuclear autoantigenic sperm protein (histone-binding) 0.010
Glra3 glycine receptor, alpha 3 0.010