The network for 'cellular component disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular component disassembly

A cellular process that results in the breakdown of a cellular component.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RSC4 Rsc4p 0.877
RSC3 Rsc3p 0.851
SFH1 Sfh1p 0.783
RSC2 Rsc2p 0.764
NPL6 Npl6p 0.755
ARP7 Arp7p 0.742
ARP9 Arp9p 0.712
STH1 Sth1p 0.685
RSC6 Rsc6p 0.653
RSC8 Rsc8p 0.580
HHF1 Hhf1p 0.529
HTL1 Htl1p 0.528
BBC1 Bbc1p 0.508
BMH2 Bmh2p 0.480
RSC58 Rsc58p 0.472
RTT102 Rtt102p 0.434
MYO5 Myo5p 0.432
SSE1 Sse1p 0.414
YOL087C hypothetical protein 0.398
CLB3 Clb3p 0.379
SUP35 Sup35p 0.374
RSC9 Rsc9p 0.343
YDJ1 Ydj1p 0.323
SRV2 Srv2p 0.307
BMH1 Bmh1p 0.295
KAR9 Kar9p 0.274
RSC1 Rsc1p 0.270
STU2 Stu2p 0.253
CDC10 Cdc10p 0.242
ASE1 Ase1p 0.224
SSK2 Ssk2p 0.217
CKS1 Cks1p 0.216
SSA1 Ssa1p 0.215
SSK1 Ssk1p 0.204
GBP2 Gbp2p 0.201
AQY2 Aqy2p 0.196
BOI1 Boi1p 0.194
DOA1 Doa1p 0.190
DBP5 Dbp5p 0.181
CDC12 Cdc12p 0.180
FPK1 Fpk1p 0.179
ZDS1 Zds1p 0.169
ABP1 Abp1p 0.160
CDC28 Cdc28p 0.157
ASF1 Asf1p 0.155
UBP2 Ubp2p 0.154
KIP1 Kip1p 0.152
NUP100 Nup100p 0.152
SSA4 Ssa4p 0.152
AIR1 Air1p 0.145
AIM3 Aim3p 0.138
TIF1 Tif1p 0.136
TEF1 Tef1p 0.136
MAD1 Mad1p 0.133
MYO3 Myo3p 0.128
STE7 Ste7p 0.125
PAF1 Paf1p 0.124
NUP170 Nup170p 0.120
SNF11 Snf11p 0.120
REB1 Reb1p 0.119
YPK1 Ypk1p 0.118
DYN1 Dyn1p 0.111
NET1 Net1p 0.110
AIM21 Aim21p 0.108
UBA1 Uba1p 0.108
CBF2 Cbf2p 0.104
KAP95 Kap95p 0.102
MEX67 Mex67p 0.102
CLU1 Clu1p 0.099
STI1 Sti1p 0.096
FAR11 Far11p 0.096
IMD3 Imd3p 0.094
DIA2 Dia2p 0.093
SVF1 Svf1p 0.090
BFA1 Bfa1p 0.088
FUN12 Fun12p 0.088
PSP2 Psp2p 0.087
ACT1 Act1p 0.085
BEM1 Bem1p 0.083
PTI1 Pti1p 0.082
HSC82 Hsc82p 0.080
TOP1 Top1p 0.079
RSC30 Rsc30p 0.078
UBP8 Ubp8p 0.078
RPM2 Rpm2p 0.078
SYF1 Syf1p 0.077
SHE3 She3p 0.077
SRP40 Srp40p 0.076
BSP1 Bsp1p 0.075
LIF1 Lif1p 0.074
URA7 Ura7p 0.073
SEC7 Sec7p 0.072
SET1 Set1p 0.072
CLB2 Clb2p 0.072
NUD1 Nud1p 0.071
MSN5 Msn5p 0.071
UBR1 Ubr1p 0.070
PBS2 Pbs2p 0.070
BDF1 Bdf1p 0.070
YEF3 Yef3p 0.068
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
wu:fv91b12 wu:fv91b12 0.378
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.295
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.253
flot1b flotillin 1b 0.205
hmga1a high mobility group AT-hook 1a 0.199
zgc:77052 zgc:77052 0.173
anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.169
prkci protein kinase C, iota 0.169
cct6a chaperonin containing TCP1, subunit 6A (zeta 1) 0.155
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.152
snrpa small nuclear ribonucleoprotein polypeptide A 0.152
dzip1 DAZ interacting protein 1 0.148
eef2l2 eukaryotic translation elongation factor 2, like 2 0.146
mfn2 mitofusin 2 0.144
srsf2 serine/arginine-rich splicing factor 2 0.135
zgc:109901 zgc:109901 0.134
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.132
kif14 kinesin family member 14 0.123
smyhc1 slow myosin heavy chain 1 0.119
prc1b protein regulator of cytokinesis 1b 0.117
nusap1 nucleolar and spindle associated protein 1 0.115
tmem93 transmembrane protein 93 0.113
krt8 keratin 8 0.110
tpm3 tropomyosin 3 0.110
sass6 spindle assembly 6 homolog (C. elegans) 0.107
zgc:91930 zgc:91930 0.106
crb2a crumbs homolog 2a 0.105
dlst dihydrolipoamide S-succinyltransferase 0.102
tra2a transformer-2 alpha 0.101
pitx3 paired-like homeodomain transcription factor 3 0.099
pcna proliferating cell nuclear antigen 0.098
si:dkey-261h17.1 si:dkey-261h17.1 0.098
zgc:101737 zgc:101737 0.097
snai1a snail homolog 1a (Drosophila) 0.096
srsf6a serine/arginine-rich splicing factor 6a 0.092
mars methionine-tRNA synthetase 0.092
cand1 cullin-associated and neddylation-dissociated 1 0.091
prp19 PRP19/PSO4 homolog (S. cerevisiae) 0.091
rrm1 ribonucleotide reductase M1 polypeptide 0.090
mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.089
smndc1 survival motor neuron domain containing 1 0.087
ift88 intraflagellar transport 88 homolog 0.087
cul1a cullin 1a 0.085
zbtb4 zinc finger and BTB domain containing 4 0.085
si:ch211-254d18.3 si:ch211-254d18.3 0.084
sucla2 succinate-CoA ligase, ADP-forming, beta subunit 0.084
mbp myelin basic protein 0.084
disc1 disrupted in schizophrenia 1 0.084
zgc:55461 zgc:55461 0.083
zgc:65979 zgc:65979 0.083
me2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.082
rpn2 ribophorin II 0.082
anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.081
dpf2l D4, zinc and double PHD fingers family 2, like 0.081
ddx39b DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b 0.081
ckma creatine kinase, muscle a 0.080
rpa1 replication protein A1 0.078
btg2 B-cell translocation gene 2 0.078
cnih cornichon homolog (Drosophila) 0.078
lmnb1 lamin B1 0.078
plxna4 plexin A4 0.078
pkd2 polycystic kidney disease 2 0.078
si:ch211-197n10.2 si:ch211-197n10.2 0.076
cotl1 coactosin-like 1 (Dictyostelium) 0.076
eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) 0.076
ube2i2 ubiquitin-conjugating enzyme E2I2 0.075
cnn3a calponin 3, acidic a 0.075
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.074
cdc16 cell division cycle 16 homolog (S. cerevisiae) 0.074
tbeta-a beta thymosin-like protein 2 0.073
mta2 metastasis associated 1 family, member 2 0.073
ran ras-related nuclear protein 0.073
smad9 MAD homolog 9 (Drosophila) 0.073
asna1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.073
si:dkey-181m9.9 si:dkey-181m9.9 0.072
cse1l chromosome segregation 1-like (S. cerevisiae) 0.072
sirt6 sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) 0.072
wnt11 wingless-type MMTV integration site family, member 11 0.072
zgc:110527 zgc:110527 0.071
mapk3 mitogen-activated protein kinase 3 0.071
usp5 ubiquitin specific protease 5 0.071
eif5a eukaryotic translation initiation factor 5A 0.071
hk1 hexokinase 1 0.071
zgc:112242 zgc:112242 0.071
syncripl synaptotagmin binding, cytoplasmic RNA interacting protein, like 0.071
lypd6 LY6/PLAUR domain containing 6 0.070
arpp19b cAMP-regulated phosphoprotein 19b 0.070
kdm5c lysine (K)-specific demethylase 5C 0.070
mdm2 transformed 3T3 cell double minute 2 homolog (mouse) 0.070
si:ch211-272f3.4 si:ch211-272f3.4 0.069
si:ch211-197h24.9 si:ch211-197h24.9 0.069
wu:fc48e01 wu:fc48e01 0.069
marcksb myristoylated alanine rich protein kinase C substrate b 0.068
kbp kif1-binding protein 0.068
eif1b eukaryotic translation initiation factor 1B 0.068
LOC553527 hypothetical protein LOC553527 0.068
ilf2 interleukin enhancer binding factor 2 0.067
atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.067
mtor mechanistic target of rapamycin (serine/threonine kinase) 0.066
si:ch211-232m7.1 si:ch211-232m7.1 0.066
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Drosophila melanogaster
Name Description Probability Func Analog Organism
pbl pebble 0.912
exo84 CG6095 gene product from transcript CG6095-RA 0.820
S6k RPS6-p70-protein kinase 0.762
beta-Spec beta Spectrin 0.752
Det Deterin 0.749
hyd hyperplastic discs 0.715
Rab11 Rab-protein 11 0.694
Dhc64C Dynein heavy chain 64C 0.595
Lis-1 Lissencephaly-1 0.579
asl asterless 0.576
Eps-15 Epidermal growth factor receptor pathway substrate clone 15 0.530
CG32038 CG32038 gene product from transcript CG32038-RA 0.514
polo CG12306 gene product from transcript CG12306-RA 0.412
atl atlastin 0.395
Rae1 CG9862 gene product from transcript CG9862-RA 0.392
Klp67A Kinesin-like protein at 67A 0.380
sec8 CG2095 gene product from transcript CG2095-RA 0.374
SMC2 CG10212 gene product from transcript CG10212-RA 0.353
dia diaphanous 0.339
flr flare 0.335
asp abnormal spindle 0.329
pAbp polyA-binding protein 0.325
cpa capping protein alpha 0.315
Ras85D Ras oncogene at 85D 0.298
mi minus 0.293
Dap160 Dynamin associated protein 160 0.281
vib vibrator 0.269
Klp3A Kinesin-like protein at 3A 0.259
Drp1 Dynamin related protein 1 0.257
mfr misfire 0.244
bru brunelleschi 0.231
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.230
chb chromosome bows 0.228
alpha-Spec alpha Spectrin 0.220
Arp14D Actin-related protein 14D 0.213
hts hu li tai shao 0.206
ari-2 ariadne 2 0.204
flw flapwing 0.203
fwd four wheel drive 0.201
Dlic Dynein light intermediate chain 0.196
serp serpentine 0.192
rig rigor mortis 0.181
CtBP C-terminal Binding Protein 0.181
mib2 mind bomb 2 0.174
eIF4G2 eukaryotic translation initiation factor 4G2 0.170
ana3 anastral spindle 3 0.167
Timp Tissue inhibitor of metalloproteases 0.165
snama something that sticks like glue 0.164
CG2865 CG2865 gene product from transcript CG2865-RA 0.159
fws four way stop 0.158
CG10267 CG10267 gene product from transcript CG10267-RB 0.151
Snr1 Snf5-related 1 0.143
su(Hw) suppressor of Hairy wing 0.140
vih vihar 0.135
Chc Clathrin heavy chain 0.130
scra scraps 0.129
ncd non-claret disjunctional 0.128
Fs(2)Ket Female sterile (2) Ketel 0.124
Hsc70-5 Heat shock protein cognate 5 0.122
BicD Bicaudal D 0.122
CycG Cyclin G 0.121
CG9572 CG9572 gene product from transcript CG9572-RA 0.119
Poc1 Proteome of centrioles 1 0.116
stumps CG31317 gene product from transcript CG31317-RC 0.114
sinu sinuous 0.110
caz cabeza 0.109
Hsp83 Heat shock protein 83 0.109
Cdc37 CG12019 gene product from transcript CG12019-RA 0.109
Hcf Host cell factor 0.107
Gasp CG10287 gene product from transcript CG10287-RB 0.103
bnl branchless 0.102
Arp87C Actin-related protein 87C 0.100
Mnt CG13316 gene product from transcript CG13316-RD 0.100
mtrm matrimony 0.100
Sas-4 CG10061 gene product from transcript CG10061-RA 0.099
WASp CG1520 gene product from transcript CG1520-RA 0.097
cher cheerio 0.097
U2af38 U2 small nuclear riboprotein auxiliary factor 38 0.095
baz bazooka 0.094
ana2 anastral spindle 2 0.094
sas-6 spindle assembly abnormal 6 0.092
pelo pelota 0.092
Hph HIF prolyl hydroxylase 0.091
RfC4 Replication factor C subunit 4 0.090
rhea CG6831 gene product from transcript CG6831-RA 0.087
CG10722 CG10722 gene product from transcript CG10722-RA 0.086
sw short wing 0.086
Mcr Macroglobulin complement-related 0.086
Mio Mlx interactor 0.082
MED1 Mediator complex subunit 1 0.082
Mef2 Myocyte enhancer factor 2 0.081
Pak3 CG14895 gene product from transcript CG14895-RA 0.080
egl egalitarian 0.079
Pp4-19C Protein phosphatase 19C 0.079
Klp10A CG1453 gene product from transcript CG1453-RA 0.078
mld molting defective 0.076
Ten-m Tenascin major 0.076
par-1 CG8201 gene product from transcript CG8201-RA 0.076
Spc25 CG7242 gene product from transcript CG7242-RA 0.072
snky sneaky 0.072
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Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 0.998
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.996
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.988
SQSTM1 sequestosome 1 0.970
ARID1A AT rich interactive domain 1A (SWI-like) 0.966
HSPA8 heat shock 70kDa protein 8 0.942
RBM8A RNA binding motif protein 8A 0.938
ACTG1 actin, gamma 1 0.889
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.843
BCL2L1 BCL2-like 1 0.831
ACTB actin, beta 0.826
TGFB1 transforming growth factor, beta 1 0.822
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.800
FKBP1A FK506 binding protein 1A, 12kDa 0.654
FGF1 fibroblast growth factor 1 (acidic) 0.642
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.632
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.632
SRSF3 serine/arginine-rich splicing factor 3 0.609
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.582
TRA2B transformer 2 beta homolog (Drosophila) 0.570
CDK2 cyclin-dependent kinase 2 0.555
FLOT2 flotillin 2 0.550
HDAC2 histone deacetylase 2 0.526
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.523
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.509
ITGB4 integrin, beta 4 0.504
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.500
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.499
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.495
VDAC1 voltage-dependent anion channel 1 0.487
BCL2 B-cell CLL/lymphoma 2 0.481
CSNK2B casein kinase 2, beta polypeptide 0.474
PBRM1 polybromo 1 0.469
FLOT1 flotillin 1 0.452
KIF23 kinesin family member 23 0.444
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.443
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.436
TRAF6 TNF receptor-associated factor 6 0.435
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.433
SRSF10 serine/arginine-rich splicing factor 10 0.422
HIST1H1C histone cluster 1, H1c 0.420
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.416
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.416
CDK1 cyclin-dependent kinase 1 0.406
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.403
EIF4A3 eukaryotic translation initiation factor 4A3 0.403
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.375
NBR1 neighbor of BRCA1 gene 1 0.374
IRAK2 interleukin-1 receptor-associated kinase 2 0.370
USP15 ubiquitin specific peptidase 15 0.360
HIST1H2BG histone cluster 1, H2bg 0.358
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.354
MARK2 MAP/microtubule affinity-regulating kinase 2 0.353
TRIM63 tripartite motif containing 63 0.342
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.326
CENPE centromere protein E, 312kDa 0.325
SEPT2 septin 2 0.324
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.318
KIF5B kinesin family member 5B 0.312
EXOSC3 exosome component 3 0.296
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.280
TPM2 tropomyosin 2 (beta) 0.276
RACGAP1 Rac GTPase activating protein 1 0.265
CORO1C coronin, actin binding protein, 1C 0.264
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.262
UBC ubiquitin C 0.256
FUNDC2 FUN14 domain containing 2 0.249
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.249
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.243
CD14 CD14 molecule 0.232
SRSF2 serine/arginine-rich splicing factor 2 0.230
CKAP5 cytoskeleton associated protein 5 0.230
POU5F1 POU class 5 homeobox 1 0.218
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.214
APC adenomatous polyposis coli 0.214
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.208
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.207
HIST1H2AE histone cluster 1, H2ae 0.207
ARID1B AT rich interactive domain 1B (SWI1-like) 0.206
HIST2H2BE histone cluster 2, H2be 0.203
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.202
EXOC1 exocyst complex component 1 0.201
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.195
CENPF centromere protein F, 350/400kDa (mitosin) 0.194
ETF1 eukaryotic translation termination factor 1 0.191
SOS1 son of sevenless homolog 1 (Drosophila) 0.191
MAPK8 mitogen-activated protein kinase 8 0.190
TOP2B topoisomerase (DNA) II beta 180kDa 0.188
LAMB1 laminin, beta 1 0.187
HIST1H2BD histone cluster 1, H2bd 0.186
MCTS1 malignant T cell amplified sequence 1 0.183
APP amyloid beta (A4) precursor protein 0.179
EXOSC10 exosome component 10 0.179
ZMYND11 zinc finger, MYND-type containing 11 0.179
RNR2 l-rRNA 0.176
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.175
KIF20A kinesin family member 20A 0.174
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.166
TEX11 testis expressed 11 0.166
KIF4A kinesin family member 4A 0.162
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism