The network for 'response to extracellular stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to extracellular stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ATG1 Atg1p 0.963
VPS30 Vps30p 0.909
RTG3 Rtg3p 0.879
TOR1 Tor1p 0.782
PFK26 Pfk26p 0.769
ATG13 Atg13p 0.742
GLN3 Gln3p 0.738
ATG21 Atg21p 0.706
SSN3 Ssn3p 0.703
HSP82 Hsp82p 0.656
SNF2 Snf2p 0.634
TPK1 Tpk1p 0.625
VPS27 Vps27p 0.607
GAL4 Gal4p 0.569
HRK1 Hrk1p 0.567
SLG1 Slg1p 0.562
SNF5 Snf5p 0.555
KSP1 Ksp1p 0.539
HDA2 Hda2p 0.533
SHP1 Shp1p 0.532
HSV2 Hsv2p 0.526
ESA1 Esa1p 0.518
ATG12 Atg12p 0.507
YPK1 Ypk1p 0.505
AFT1 Aft1p 0.504
GAL11 Gal11p 0.502
SNF6 Snf6p 0.500
VHS1 Vhs1p 0.496
MSN2 Msn2p 0.489
HSP32 Hsp32p 0.486
SEC2 Sec2p 0.480
MKS1 Mks1p 0.468
PMP1 Pmp1p 0.461
GPR1 Gpr1p 0.450
MIG1 Mig1p 0.444
SNF4 Snf4p 0.442
PTK2 Ptk2p 0.433
ASP3-1 Asp3-1p 0.432
ATG20 Atg20p 0.426
ATG23 Atg23p 0.420
VPS36 Vps36p 0.417
HSP33 Hsp33p 0.413
AQY2 Aqy2p 0.410
ATG4 Atg4p 0.408
DBF2 Dbf2p 0.402
RIM101 Rim101p 0.383
RIM15 Rim15p 0.380
ASP3-3 Asp3-3p 0.377
ATG16 Atg16p 0.375
HSP42 Hsp42p 0.357
ASP3-4 Asp3-4p 0.355
ENA5 Ena5p 0.355
CYC8 Cyc8p 0.354
STP22 Stp22p 0.347
COG6 Cog6p 0.346
MDS3 Mds3p 0.342
ATG8 Atg8p 0.341
ASP3-2 Asp3-2p 0.333
YPL247C hypothetical protein 0.330
GAL80 Gal80p 0.330
ACS1 Acs1p 0.330
RTS1 Rts1p 0.329
HAP5 Hap5p 0.324
ATG3 Atg3p 0.319
VPS41 Vps41p 0.314
MIG3 Mig3p 0.314
PEP5 Pep5p 0.312
YDJ1 Ydj1p 0.307
IZH4 Izh4p 0.306
CCZ1 Ccz1p 0.292
RUD3 Rud3p 0.290
GCN1 Gcn1p 0.284
VID24 Vid24p 0.283
HAP4 Hap4p 0.282
ATG17 Atg17p 0.280
DOT6 Dot6p 0.279
DST1 Dst1p 0.276
RVS167 Rvs167p 0.271
ATG29 Atg29p 0.267
BUD3 Bud3p 0.266
PPH21 Pph21p 0.265
CIS1 Cis1p 0.255
PFK1 Pfk1p 0.252
IML1 Iml1p 0.249
ATG9 Atg9p 0.244
NET1 Net1p 0.244
ATG2 Atg2p 0.243
RPN4 Rpn4p 0.242
NUR1 Nur1p 0.238
YKR015C hypothetical protein 0.234
MON1 Mon1p 0.234
ARP7 Arp7p 0.234
SIN3 Sin3p 0.233
PMC1 Pmc1p 0.232
OM45 Om45p 0.230
RRD1 Rrd1p 0.226
CKA2 Cka2p 0.223
PTC6 Ptc6p 0.220
YIP4 Yip4p 0.217
HAL5 Hal5p 0.217
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.176
atg-18 Protein ATG-18 0.147
K10C8.3 Protein K10C8.3 0.139
F53F10.2 Protein F53F10.2 0.103
daf-2 Protein DAF-2 0.078
pal-1 Protein PAL-1 0.077
cat-1 Protein CAT-1 0.072
eat-4 Protein EAT-4 0.071
vab-3 Protein VAB-3 0.069
ifg-1 Protein IFG-1 0.061
pdfr-1 Protein PDFR-1 0.056
pmk-1 Protein PMK-1 0.055
gpa-14 Protein GPA-14 0.051
gld-2 Protein GLD-2 0.051
fkh-2 Protein FKH-2 0.050
unc-62 Protein UNC-62 0.049
emb-5 Protein EMB-5 0.049
plc-1 Protein PLC-1 0.049
egl-46 Protein EGL-46 0.048
egl-30 Protein EGL-30 0.043
CELE_C01G6.4 Protein C01G6.4 0.041
gpb-1 Protein GPB-1 0.040
che-13 Protein CHE-13 0.038
vav-1 Protein VAV-1 0.037
exc-5 Protein EXC-5 0.037
aak-2 Protein AAK-2 0.035
par-5 Protein PAR-5 0.035
hnd-1 Protein HND-1 0.035
ser-2 Protein SER-2 0.035
CELE_Y57G11C.15 Protein Y57G11C.15 0.034
set-1 Protein SET-1 0.034
crn-4 Protein CRN-4 0.033
nhr-120 Protein NHR-120 0.033
mrck-1 Protein MRCK-1 0.032
cpr-4 Protein CPR-4 0.031
sir-2.1 Protein SIR-2.1 0.030
ess-2 Protein ESS-2 0.030
C27C12.1 Protein C27C12.1 0.029
phip-1 Protein PHIP-1 0.029
aex-3 Protein AEX-3 0.029
R05F9.9 Protein R05F9.9 0.029
pde-4 Protein PDE-4 0.029
mek-2 Protein MEK-2 0.028
tbc-9 Protein TBC-9 0.028
ist-1 Protein IST-1 0.028
sel-7 Protein SEL-7 0.027
mpk-1 Protein MPK-1 0.027
Y77E11A.1 Protein Y77E11A.1 0.027
bbs-8 Protein BBS-8 0.027
eat-2 Protein EAT-2 0.027
lin-36 Protein LIN-36 0.026
cmd-1 Protein CMD-1 0.026
rskd-1 Protein RSKD-1 0.026
dcn-1 Protein DCN-1 0.026
unc-36 Protein UNC-36 0.025
egal-1 Protein EGAL-1 0.025
dpy-31 Protein DPY-31 0.025
C18E3.3 Protein C18E3.3 0.025
atg-13 Protein ATG-13 0.024
pmt-2 Protein PMT-2 0.024
Y47D3B.11 Protein Y47D3B.11 0.024
bir-1 Protein BIR-1 0.023
ccf-1 Protein CCF-1 0.023
fbf-1 Protein FBF-1 0.023
Y82E9BR.13 Protein Y82E9BR.13 0.022
fdps-1 Protein FDPS-1 0.022
mig-6 Protein MIG-6 0.022
fhod-1 Protein FHOD-1 0.022
unc-9 Protein UNC-9 0.022
Y71F9AL.9 Protein Y71F9AL.9 0.022
cka-2 Protein CKA-2 0.022
rgs-3 Protein RGS-3 0.022
crm-1 Protein CRM-1 0.021
H18N23.2 Protein H18N23.2 0.021
pcaf-1 Protein PCAF-1 0.021
ser-6 Protein SER-6 0.021
prp-21 Protein PRP-21 0.021
lin-5 Protein LIN-5 0.021
W06D11.1 Protein W06D11.1 0.021
egl-5 Protein EGL-5 0.021
emb-9 Protein EMB-9 0.021
lin-66 Protein LIN-66 0.021
unc-83 Protein UNC-83 0.021
uba-1 Protein UBA-1 0.021
bbs-2 Protein BBS-2 0.021
F49C12.9 Protein F49C12.9 0.021
C05E11.7 Protein C05E11.7 0.021
glb-33 Protein GLB-33 0.021
gpb-2 Protein GPB-2 0.021
cfim-2 Protein CFIM-2 0.021
otub-1 Protein OTUB-1 0.020
tph-1 Protein TPH-1 0.020
W05B10.4 Protein W05B10.4 0.020
utx-1 Protein UTX-1 0.020
R12E2.2 Protein R12E2.2 0.020
apl-1 Protein APL-1 0.020
lat-1 Protein LAT-1 0.019
F32A5.3 Protein F32A5.3 0.019
lron-1 Protein LRON-1 0.019
sem-5 Protein SEM-5 0.019
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gata5 GATA-binding protein 5 0.287
gpia glucose phosphate isomerase a 0.135
crh corticotropin releasing hormone 0.132
ca2 carbonic anhydrase II 0.097
fgf3 fibroblast growth factor 3 0.091
hnf1ba HNF1 homeobox Ba 0.090
prl prolactin 0.084
igf1rb insulin-like growth factor 1b receptor 0.071
hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 0.069
oxtl oxytocin-like 0.064
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.061
pou1f1 POU domain, class 1, transcription factor 1 0.059
bmp2b bone morphogenetic protein 2b 0.058
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.057
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.055
shha sonic hedgehog a 0.055
ihha Indian hedgehog homolog a 0.053
vdra vitamin D receptor a 0.051
wnt11r wingless-type MMTV integration site family, member 11, related 0.051
jag2 jagged 2 0.050
cav1 caveolin 1 0.049
ins preproinsulin 0.048
odc1 ornithine decarboxylase 1 0.045
mt2 metallothionein 2 0.043
rbp4 retinol binding protein 4, plasma 0.041
cyp1b1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.040
glula glutamate-ammonia ligase (glutamine synthase) a 0.038
bmp4 bone morphogenetic protein 4 0.038
tm4sf4 transmembrane 4 L six family member 4 0.038
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.037
mao monoamine oxidase 0.037
si:rp71-39b20.7 si:rp71-39b20.7 0.035
mst1 macrophage stimulating 1 (hepatocyte growth factor-like) 0.033
fabp7a fatty acid binding protein 7, brain, a 0.033
crabp2a cellular retinoic acid binding protein 2, a 0.033
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.033
igf1 insulin-like growth factor 1 0.033
igf2a insulin-like growth factor 2a 0.032
slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.032
ca8 carbonic anhydrase VIII 0.032
tp53 tumor protein p53 0.032
tm9sf2 transmembrane 9 superfamily member 2 0.032
flh floating head 0.032
foxa2 forkhead box A2 0.031
drd2a dopamine receptor D2a 0.031
ctgf connective tissue growth factor 0.030
fgfrl1a fibroblast growth factor receptor-like 1a 0.029
atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 0.029
neurog3 neurogenin 3 0.029
tac1 tachykinin 1 0.027
zgc:56136 zgc:56136 0.027
ghra growth hormone receptor a 0.026
creb3l3l cAMP responsive element binding protein 3-like 3 like 0.026
nr1i2 nuclear receptor subfamily 1, group I, member 2 0.026
cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a 0.026
dbh dopamine beta hydroxylase 0.025
otpa orthopedia homolog a 0.025
gamt guanidinoacetate N-methyltransferase 0.025
mmp14a matrix metalloproteinase 14a (membrane-inserted) 0.025
cahz carbonic anhydrase 0.024
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.024
itgb1b.1 integrin, beta 1b.1 0.024
ptgs1 prostaglandin-endoperoxide synthase 1 0.024
ghrb growth hormone receptor b 0.023
pbx4 pre-B-cell leukemia transcription factor 4 0.023
ctsl1a cathepsin L, 1 a 0.023
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.023
anxa13 annexin A13 0.023
igf2b insulin-like growth factor 2b 0.022
LOC100006361 galanin-like 0.022
tshb thyroid stimulating hormone, beta subunit 0.022
xbp1 X-box binding protein 1 0.022
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.022
col1a2 collagen, type I, alpha 2 0.021
ef1a elongation factor 1-alpha 0.021
ext2 exostoses (multiple) 2 0.021
stxbp2 syntaxin binding protein 2 0.020
si:dkey-228g21.4 si:dkey-228g21.4 0.020
egr2a early growth response 2a 0.020
igfbp1b insulin-like growth factor binding protein 1b 0.020
bhlhe40 basic helix-loop-helix family, member e40 0.020
kdm5c lysine (K)-specific demethylase 5C 0.020
mtp microsomal triglyceride transfer protein 0.019
bactin1 bactin1 0.018
mc3r melanocortin 3 receptor 0.018
aldob aldolase b, fructose-bisphosphate 0.018
ndfip1 Nedd4 family interacting protein 1 0.018
fshb follicle stimulating hormone, beta polypeptide 0.018
apoeb apolipoprotein Eb 0.018
rag1 recombination activating gene 1 0.018
sst1.1 somatostatin 1, tandem duplicate 1 0.017
ptger4b prostaglandin E receptor 4 (subtype EP4) b 0.017
notch1a notch homolog 1a 0.017
pdlim1 PDZ and LIM domain 1 (elfin) 0.016
ptena phosphatase and tensin homolog A 0.016
lama5 laminin, alpha 5 0.016
angptl2 angiopoietin-like 2 0.016
lifrb leukemia inhibitory factor receptor alpha b 0.016
tp53bp2 tumor protein p53 binding protein, 2 0.016
idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.016
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
foxo forkhead box, sub-group O 0.961
dm diminutive 0.955
Gp150 CG5820 gene product from transcript CG5820-RA 0.948
Atg1 Autophagy-specific gene 1 0.948
Ras85D Ras oncogene at 85D 0.940
Atg18 Autophagy-specific gene 18 0.921
Pten CG5671 gene product from transcript CG5671-RB 0.897
Atg7 Autophagy-specific gene 7 0.876
Rab7 Rab-protein 7 0.842
Tsc1 CG6147 gene product from transcript CG6147-RA 0.836
Rab5 Rab-protein 5 0.829
RagA CG11968 gene product from transcript CG11968-RA 0.827
Trxr-1 Thioredoxin reductase-1 0.779
gig gigas 0.763
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.739
Atg8a Autophagy-specific gene 8a 0.734
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.718
Hsp68 Heat shock protein 68 0.668
l(3)82Fd CG32464 gene product from transcript CG32464-RR 0.660
CycD Cyclin D 0.639
bsk basket 0.628
Syx17 Syntaxin 17 0.618
hep hemipterous 0.599
Atg2 Autophagy-specific gene 2 0.561
caz cabeza 0.557
Akt1 CG4006 gene product from transcript CG4006-RA 0.543
trx trithorax 0.542
S6k RPS6-p70-protein kinase 0.527
Stat92E Signal-transducer and activator of transcription protein at 92E 0.510
Hsp27 Heat shock protein 27 0.509
CG6543 CG6543 gene product from transcript CG6543-RA 0.498
Lk6 CG17342 gene product from transcript CG17342-RA 0.497
CG1347 CG1347 gene product from transcript CG1347-RB 0.496
CG42863 CG42863 gene product from transcript CG42863-RB 0.487
Hsp70Aa Heat-shock-protein-70Aa 0.483
Sox14 Sox box protein 14 0.461
Mad Mothers against dpp 0.449
Atg13 Autophagy-specific gene 13 0.416
dl dorsal 0.403
Vps16A Vacuolar protein sorting 16A 0.393
stv starvin 0.382
Ugt35a UDP-glycosyltransferase 35a 0.380
Ilp2 Insulin-like peptide 2 0.375
p38b CG7393 gene product from transcript CG7393-RA 0.369
klu klumpfuss 0.368
Gr64e Gustatory receptor 64e 0.366
Thor CG8846 gene product from transcript CG8846-RA 0.357
Hsp26 Heat shock protein 26 0.354
G-oalpha47A G protein oalpha 47A 0.350
yki yorkie 0.338
Marf Mitochondrial assembly regulatory factor 0.320
rl rolled 0.319
Gga CG3002 gene product from transcript CG3002-RB 0.317
Atg9 Autophagy-specific gene 9 0.305
HLH106 Helix loop helix protein 106 0.302
Jafrac1 thioredoxin peroxidase 1 0.302
Tpi Triose phosphate isomerase 0.286
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.285
Dcr-2 Dicer-2 0.284
atl atlastin 0.284
CG3004 CG3004 gene product from transcript CG3004-RA 0.281
Ser Serrate 0.272
spin spinster 0.271
Gr64a Gustatory receptor 64a 0.271
rut rutabaga 0.265
msn misshapen 0.264
EcR Ecdysone receptor 0.253
Nrg Neuroglian 0.249
dco discs overgrown 0.246
CdsA CDP diglyceride synthetase 0.240
CG8773 CG8773 gene product from transcript CG8773-RB 0.235
dnc dunce 0.229
Thiolase CG4581 gene product from transcript CG4581-RA 0.227
Hr96 Hormone receptor-like in 96 0.221
Gr64c Gustatory receptor 64c 0.221
mof males absent on the first 0.219
smt3 CG4494 gene product from transcript CG4494-RA 0.217
aop anterior open 0.216
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.213
trpml transient receptor potential mucolipin 0.212
Trx-2 thioredoxin-2 0.208
vri vrille 0.200
Nc Nedd2-like caspase 0.200
Hcf Host cell factor 0.199
Rac1 CG2248 gene product from transcript CG2248-RA 0.197
CG6569 CG6569 gene product from transcript CG6569-RA 0.197
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.197
Sh3beta CG8582 gene product from transcript CG8582-RD 0.196
CG12672 CG12672 gene product from transcript CG12672-RA 0.196
Atg6 Autophagy-specific gene 6 0.194
pan pangolin 0.193
Mekk1 CG7717 gene product from transcript CG7717-RB 0.192
Jra Jun-related antigen 0.188
Poxn Pox neuro 0.180
shd shade 0.179
Gr63a Gustatory receptor 63a 0.179
Ets97D Ets at 97D 0.179
Fatp Fatty acid (long chain) transport protein 0.176
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.174
CG2852 CG2852 gene product from transcript CG2852-RA 0.173
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.974
ESR1 estrogen receptor 1 0.945
ATG3 ATG3 autophagy related 3 homolog (S. cerevisiae) 0.920
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.919
SQSTM1 sequestosome 1 0.902
GABARAP GABA(A) receptor-associated protein 0.883
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.870
NCOA1 nuclear receptor coactivator 1 0.851
EGFR epidermal growth factor receptor 0.783
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.770
CREBBP CREB binding protein 0.764
GSK3B glycogen synthase kinase 3 beta 0.754
SIRT1 sirtuin 1 0.740
GABARAPL1 GABA(A) receptor-associated protein like 1 0.738
EP300 E1A binding protein p300 0.685
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.681
ATG13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.673
RARA retinoic acid receptor, alpha 0.671
BECN1 beclin 1, autophagy related 0.604
ATG5 ATG5 autophagy related 5 homolog (S. cerevisiae) 0.584
MAPK1 mitogen-activated protein kinase 1 0.568
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.567
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.558
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.544
CAV1 caveolin 1, caveolae protein, 22kDa 0.537
INSR insulin receptor 0.505
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.504
MAPT microtubule-associated protein tau 0.496
IL1R1 interleukin 1 receptor, type I 0.475
DUSP1 dual specificity phosphatase 1 0.449
NCOR1 nuclear receptor corepressor 1 0.447
HDAC1 histone deacetylase 1 0.437
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.396
SREBF2 sterol regulatory element binding transcription factor 2 0.363
TSC2 tuberous sclerosis 2 0.341
BRCA1 breast cancer 1, early onset 0.340
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.329
NCOR2 nuclear receptor corepressor 2 0.313
ENG endoglin 0.312
KAT2B K(lysine) acetyltransferase 2B 0.304
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.300
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.299
HSPB1 heat shock 27kDa protein 1 0.291
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.284
CCND3 cyclin D3 0.282
ULK1 unc-51-like kinase 1 (C. elegans) 0.282
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.268
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.267
FKBP1A FK506 binding protein 1A, 12kDa 0.267
DLG4 discs, large homolog 4 (Drosophila) 0.265
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.262
CDK6 cyclin-dependent kinase 6 0.257
IRS2 insulin receptor substrate 2 0.254
BMP2 bone morphogenetic protein 2 0.253
TGFB1 transforming growth factor, beta 1 0.250
HNF4A hepatocyte nuclear factor 4, alpha 0.247
NCOA3 nuclear receptor coactivator 3 0.246
VEGFA vascular endothelial growth factor A 0.240
MYCN v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.237
ACACA acetyl-CoA carboxylase alpha 0.227
BCL3 B-cell CLL/lymphoma 3 0.224
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.218
APP amyloid beta (A4) precursor protein 0.214
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.208
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.208
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.207
NCOA2 nuclear receptor coactivator 2 0.207
MAPK8 mitogen-activated protein kinase 8 0.203
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.202
PINK1 PTEN induced putative kinase 1 0.201
CRYGC crystallin, gamma C 0.201
TP53 tumor protein p53 0.197
MPDZ multiple PDZ domain protein 0.188
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.187
SP1 Sp1 transcription factor 0.183
RXRA retinoid X receptor, alpha 0.182
HDAC4 histone deacetylase 4 0.182
RB1CC1 RB1-inducible coiled-coil 1 0.181
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.177
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.176
AR androgen receptor 0.168
DCTN1 dynactin 1 0.164
NRP1 neuropilin 1 0.156
PDPK1 3-phosphoinositide dependent protein kinase-1 0.154
FOXO1 forkhead box O1 0.153
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.149
CNOT6 CCR4-NOT transcription complex, subunit 6 0.149
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.145
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.144
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.141
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.140
SH3KBP1 SH3-domain kinase binding protein 1 0.140
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.138
HTT huntingtin 0.134
MED25 mediator complex subunit 25 0.133
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.132
PPARG peroxisome proliferator-activated receptor gamma 0.128
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.128
EED embryonic ectoderm development 0.127
ESR2 estrogen receptor 2 (ER beta) 0.127
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Esr1 estrogen receptor 1 (alpha) 0.997
Pten phosphatase and tensin homolog 0.975
Drd2 dopamine receptor D2 0.946
Pparg peroxisome proliferator activated receptor gamma 0.946
Ctnnb1 catenin (cadherin associated protein), beta 1 0.923
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.919
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.918
Nos1 nitric oxide synthase 1, neuronal 0.904
Insr insulin receptor 0.900
Trp53 transformation related protein 53 0.880
Ar androgen receptor 0.846
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.838
Sqstm1 sequestosome 1 0.834
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.779
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.766
Trp63 transformation related protein 63 0.743
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.741
Apoe apolipoprotein E 0.736
Axl AXL receptor tyrosine kinase 0.733
Lep leptin 0.729
Prlr prolactin receptor 0.711
Lepr leptin receptor 0.700
Apc adenomatosis polyposis coli 0.687
Nf1 neurofibromatosis 1 0.667
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.662
Tgfbr2 transforming growth factor, beta receptor II 0.661
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.658
Nos3 nitric oxide synthase 3, endothelial cell 0.649
Kl klotho 0.645
Dlg4 discs, large homolog 4 (Drosophila) 0.643
Bmp4 bone morphogenetic protein 4 0.622
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.622
Lhx3 LIM homeobox protein 3 0.618
Kit kit oncogene 0.594
Sstr4 somatostatin receptor 4 0.593
Atg12 autophagy-related 12 (yeast) 0.575
Bbs4 Bardet-Biedl syndrome 4 (human) 0.573
Fgfr2 fibroblast growth factor receptor 2 0.564
Ghr growth hormone receptor 0.563
Kiss1 KiSS-1 metastasis-suppressor 0.537
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.529
Lef1 lymphoid enhancer binding factor 1 0.527
Tgfb1 transforming growth factor, beta 1 0.526
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.525
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.518
Bglap bone gamma carboxyglutamate protein 0.513
Rb1 retinoblastoma 1 0.495
Pgr progesterone receptor 0.483
Prkcc protein kinase C, gamma 0.480
Pnpla2 patatin-like phospholipase domain containing 2 0.430
Msx1 homeobox, msh-like 1 0.418
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.415
Egfr epidermal growth factor receptor 0.409
Fgf23 fibroblast growth factor 23 0.401
Cav1 caveolin 1, caveolae protein 0.397
Pax8 paired box gene 8 0.389
Irs2 insulin receptor substrate 2 0.379
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.379
Thrb thyroid hormone receptor beta 0.374
Hand1 heart and neural crest derivatives expressed transcript 1 0.366
Thra thyroid hormone receptor alpha 0.366
Ccl2 chemokine (C-C motif) ligand 2 0.358
Tbx1 T-box 1 0.357
Mapk14 mitogen-activated protein kinase 14 0.348
Fst follistatin 0.347
Fgfr4 fibroblast growth factor receptor 4 0.340
Gpc3 glypican 3 0.340
Col1a1 collagen, type I, alpha 1 0.330
Mybph myosin binding protein H 0.328
Grb10 growth factor receptor bound protein 10 0.325
Fosb FBJ osteosarcoma oncogene B 0.317
Ihh Indian hedgehog 0.313
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.302
Egr1 early growth response 1 0.302
Gdnf glial cell line derived neurotrophic factor 0.300
Myod1 myogenic differentiation 1 0.299
Vegfa vascular endothelial growth factor A 0.297
Hbb-b1 hemoglobin, beta adult major chain 0.297
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.296
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.294
Bmp7 bone morphogenetic protein 7 0.294
Sfrp2 secreted frizzled-related protein 2 0.294
Rxra retinoid X receptor alpha 0.290
Gjb5 gap junction protein, beta 5 0.286
Sstr1 somatostatin receptor 1 0.286
Tsc1 tuberous sclerosis 1 0.280
Psen1 presenilin 1 0.276
Fgf8 fibroblast growth factor 8 0.274
Inhba inhibin beta-A 0.266
Mb myoglobin 0.264
Nos2 nitric oxide synthase 2, inducible 0.257
Mpz myelin protein zero 0.255
Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 0.253
Gcgr glucagon receptor 0.251
Fshr follicle stimulating hormone receptor 0.251
Wnt4 wingless-related MMTV integration site 4 0.250
Per3 period homolog 3 (Drosophila) 0.246
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.243
Bdkrb2 bradykinin receptor, beta 2 0.243
Lrp6 low density lipoprotein receptor-related protein 6 0.237
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Pnlip pancreatic lipase 0.863
Cd14 CD14 molecule 0.820
Apcs amyloid P component, serum 0.809
Fabp1 fatty acid binding protein 1, liver 0.796
Cpb1 carboxypeptidase B1 (tissue) 0.781
Hpx hemopexin 0.776
Rbp2 retinol binding protein 2, cellular 0.745
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.717
Fga fibrinogen alpha chain 0.683
Il1r2 interleukin 1 receptor, type II 0.678
Slc12a3 solute carrier family 12 (sodium/chloride transporters), member 3 0.644
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.628
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.617
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.614
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.605
Fgg fibrinogen gamma chain 0.602
A1i3 alpha-1-inhibitor III 0.602
Rup2 urinary protein 2 0.602
Cela2a chymotrypsin-like elastase family, member 2A 0.580
Clcn5 chloride channel 5 0.569
Col1a1 collagen, type I, alpha 1 0.567
Serpina4 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.566
Mmp3 matrix metallopeptidase 3 0.564
Bcl2 B-cell CLL/lymphoma 2 0.559
Kcne1 potassium voltage-gated channel, Isk-related family, member 1 0.558
Dnase1l3 deoxyribonuclease 1-like 3 0.557
Aqp9 aquaporin 9 0.551
Tshr thyroid stimulating hormone receptor 0.533
Cxcl10 chemokine (C-X-C motif) ligand 10 0.530
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.529
Testin testin gene 0.527
Cela1 chymotrypsin-like elastase family, member 1 0.524
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.524
Ahsg alpha-2-HS-glycoprotein 0.501
Prl8a2 prolactin family 8, subfamily a, member 2 0.499
Apoh apolipoprotein H (beta-2-glycoprotein I) 0.496
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.491
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.488
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.482
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.475
Mmp9 matrix metallopeptidase 9 0.470
Clca4 chloride channel accessory 4 0.470
Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 0.464
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.459
Prss1 protease, serine, 1 (trypsin 1) 0.456
Mrgprf MAS-related GPR, member F 0.456
Apoa1 apolipoprotein A-I 0.454
Np4 defensin NP-4 precursor 0.452
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.451
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.450
Ephx1 epoxide hydrolase 1, microsomal 0.449
Mgst2 microsomal glutathione S-transferase 2 0.447
Ptgs2 prostaglandin-endoperoxide synthase 2 0.442
Sstr2 somatostatin receptor 2 0.441
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.439
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.438
Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 0.437
Zp3 zona pellucida glycoprotein 3 (sperm receptor) 0.432
Adam7 ADAM metallopeptidase domain 7 0.432
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.431
Orm1 orosomucoid 1 0.428
Reg1a regenerating islet-derived 1 alpha 0.427
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.427
Nfasc neurofascin 0.426
Ubb ubiquitin B 0.425
Fn1 fibronectin 1 0.418
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.416
Sftpd surfactant protein D 0.416
Plau plasminogen activator, urokinase 0.415
COX1 cytochrome c oxidase subunit 1 0.414
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.413
Hspb1 heat shock protein 1 0.412
Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 0.412
Klk8 kallikrein related-peptidase 8 0.408
Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 0.408
Bgn biglycan 0.405
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.404
LOC293989 cytochrome P450-like 0.401
Chrng cholinergic receptor, nicotinic, gamma 0.399
Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 0.396
Ppy pancreatic polypeptide 0.395
Ivl involucrin 0.394
Gja6 gap junction protein, alpha 6 0.392
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.391
Cxcl2 chemokine (C-X-C motif) ligand 2 0.389
Tac1 tachykinin 1 0.389
Fut1 fucosyltransferase 1 0.388
Spink1 serine peptidase inhibitor, Kazal type 1 0.385
Pzp pregnancy-zone protein 0.377
Gstm2 glutathione S-transferase mu 2 0.376
Ftl ferritin, light polypeptide 0.376
Aqp8 aquaporin 8 0.374
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.372
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.372
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.368
Gdf10 growth differentiation factor 10 0.368
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.364
Apoa2 apolipoprotein A-II 0.363
Gja1 gap junction protein, alpha 1 0.362
Eln elastin 0.360