The network for 'synapsis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

synapsis

The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Synapsis begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ZIP1 Zip1p 0.986
RED1 Red1p 0.965
MEK1 Mek1p 0.947
MSH4 Msh4p 0.921
HOP1 Hop1p 0.905
PCH2 Pch2p 0.895
CST9 Cst9p 0.738
ZIP2 Zip2p 0.725
MND1 Mnd1p 0.621
HFM1 Hfm1p 0.541
NDT80 Ndt80p 0.533
SMC4 Smc4p 0.466
IME2 Ime2p 0.463
BRN1 Brn1p 0.384
SPO22 Spo22p 0.233
MSH5 Msh5p 0.223
MLH3 Mlh3p 0.220
DMC1 Dmc1p 0.217
CSM4 Csm4p 0.190
PDS5 Pds5p 0.176
HSL1 Hsl1p 0.159
PDS1 Pds1p 0.130
SPO11 Spo11p 0.120
ECM11 Ecm11p 0.112
IRR1 Irr1p 0.090
REC8 Rec8p 0.087
MEI4 Mei4p 0.086
NDJ1 Ndj1p 0.081
SPO16 Spo16p 0.070
YCS4 Ycs4p 0.057
SWT1 Swt1p 0.053
ECO1 Eco1p 0.040
MSH3 Msh3p 0.037
MAM1 Mam1p 0.037
REC114 Rec114p 0.037
RAD17 Rad17p 0.035
UME6 Ume6p 0.034
HDA2 Hda2p 0.034
YPR174C hypothetical protein 0.033
SRD1 Srd1p 0.033
EST1 Est1p 0.032
CLB6 Clb6p 0.031
SPO74 Spo74p 0.030
CSM2 Csm2p 0.030
PSY2 Psy2p 0.028
RAD55 Rad55p 0.027
YJR030C hypothetical protein 0.027
IME4 Ime4p 0.026
SAE3 Sae3p 0.026
ECM9 Ecm9p 0.026
LEU2 Leu2p 0.025
YLR264C-A hypothetical protein 0.025
SPL2 Spl2p 0.025
YIG1 Yig1p 0.024
HXT3 Hxt3p 0.024
PBP2 Pbp2p 0.023
YOL038C-A hypothetical protein 0.023
YLR162W hypothetical protein 0.023
CLB1 Clb1p 0.022
CHA1 Cha1p 0.021
GAL2 Gal2p 0.021
SMC1 Smc1p 0.020
ARP10 Arp10p 0.020
IME1 Ime1p 0.020
SCC2 Scc2p 0.020
CUP1-1 Cup1-1p 0.020
ZPS1 Zps1p 0.020
MER1 Mer1p 0.019
CDC16 Cdc16p 0.019
CDC20 Cdc20p 0.019
YAR068W hypothetical protein 0.018
ATP6 Atp6p 0.018
PCL9 Pcl9p 0.018
YBL044W hypothetical protein 0.018
ARG8 Arg8p 0.018
FMT1 Fmt1p 0.018
RNR2 Rnr2p 0.018
MMS1 Mms1p 0.017
YPR157W hypothetical protein 0.017
MLH1 Mlh1p 0.017
HOP2 Hop2p 0.017
CPD1 Cpd1p 0.017
OPT2 Opt2p 0.016
BDS1 Bds1p 0.016
YKR075C hypothetical protein 0.016
SSP1 Ssp1p 0.016
YBR013C hypothetical protein 0.016
CAK1 Cak1p 0.016
YLR042C hypothetical protein 0.015
YJL181W hypothetical protein 0.015
YMR144W hypothetical protein 0.015
NUP82 Nup82p 0.015
XRS2 Xrs2p 0.015
RAD53 Rad53p 0.015
MAD3 Mad3p 0.015
IZH4 Izh4p 0.014
RNP1 Rnp1p 0.014
HPF1 Hpf1p 0.014
SGV1 Sgv1p 0.014
UPS3 Ups3p 0.014
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
F21F3.4 Protein F21F3.4 0.396
D1081.7 Protein D1081.7 0.304
exo-1 Protein EXO-1 0.277
glh-3 Protein GLH-3 0.239
F13D12.5 Protein F13D12.5 0.199
zim-3 Protein ZIM-3 0.196
htp-1 Protein HTP-1 0.170
ucr-2.3 Protein UCR-2.3 0.147
pgl-2 Protein PGL-2 0.133
R07B7.2 Protein R07B7.2 0.129
zyg-9 Protein ZYG-9 0.126
duo-1 Protein DUO-1 0.122
mre-11 Protein MRE-11 0.109
pgl-1 Protein PGL-1 0.106
glh-4 Protein GLH-4 0.104
wago-1 Protein WAGO-1 0.088
M01A10.1 Protein M01A10.1 0.080
ani-2 Protein ANI-2 0.074
rad-50 Protein RAD-50 0.074
san-1 Protein SAN-1 0.071
ZC410.3 Protein ZC410.3 0.071
fbf-2 Protein FBF-2 0.068
C35D10.7 Protein C35D10.7 0.066
bub-1 Protein BUB-1 0.061
him-3 Protein HIM-3 0.060
CELE_C38D4.4 Protein C38D4.4 0.059
mcm-5 Protein MCM-5 0.058
csr-1 Protein CSR-1 0.057
vha-18 Protein VHA-18 0.056
set-22 Protein SET-22 0.056
C48B4.10 Protein C48B4.10 0.052
T02G5.12 Protein T02G5.12 0.051
sun-1 Protein SUN-1 0.051
R05F9.11 Protein R05F9.11 0.050
ppw-2 Protein PPW-2 0.048
gld-3 Protein GLD-3 0.048
cyk-1 Protein CYK-1 0.045
mcm-6 Protein MCM-6 0.044
nmy-2 Protein NMY-2 0.044
nxf-2 Protein NXF-2 0.044
F55G1.5 Protein F55G1.5 0.041
wago-9 Protein WAGO-9 0.041
K06H7.7 Protein K06H7.7 0.040
elpc-3 Protein ELPC-3 0.040
knl-1 Protein KNL-1 0.039
F30F8.1 Protein F30F8.1 0.039
R02F2.7 Protein R02F2.7 0.037
D2096.11 Protein D2096.11 0.036
cdk-9 Protein CDK-9 0.036
CELE_F54D5.9 Protein F54D5.9 0.035
F25B5.2 Protein F25B5.2 0.035
cec-9 Protein CEC-9 0.035
got-2.1 Protein GOT-2.1 0.035
smc-5 Protein SMC-5 0.034
spd-2 Protein SPD-2 0.034
Y34D9A.3 Protein Y34D9A.3 0.033
glp-1 Protein GLP-1 0.033
C27B7.5 Protein C27B7.5 0.032
hpo-32 Protein HPO-32 0.032
glh-1 Protein GLH-1 0.031
ife-3 Protein IFE-3 0.031
W03G9.2 Protein W03G9.2 0.031
retr-1 Protein RETR-1 0.031
T26A5.2 Protein T26A5.2 0.031
zim-2 Protein ZIM-2 0.030
puf-8 Protein PUF-8 0.030
coh-3 Protein COH-3 0.030
hil-4 Protein HIL-4 0.029
fbf-1 Protein FBF-1 0.028
rfc-4 Protein RFC-4 0.028
W03G9.3 Protein W03G9.3 0.027
ZK632.5 Protein ZK632.5 0.026
C42C1.8 Protein C42C1.8 0.026
cas-2 Protein CAS-2 0.026
rad-54 Protein RAD-54 0.026
C30G12.6 Protein C30G12.6 0.024
plk-1 Protein PLK-1 0.024
skr-17 Protein SKR-17 0.024
btb-20 Protein BTB-20 0.024
zen-4 Protein ZEN-4 0.023
W03C9.2 Protein W03C9.2 0.023
nra-1 Protein NRA-1 0.023
CELE_Y57A10A.3 Protein Y57A10A.3 0.023
zhp-3 Protein ZHP-3 0.022
F26H11.4 Protein F26H11.4 0.022
inx-21 Protein INX-21 0.022
CELE_C17E4.4 Protein C17E4.4 0.021
F35G12.5 Protein F35G12.5 0.021
C31H1.8 Protein C31H1.8 0.021
thoc-3 Protein THOC-3 0.021
mut-7 Protein MUT-7 0.021
B0001.2 Protein B0001.2 0.021
bath-42 Protein BATH-42 0.020
dpl-1 Protein DPL-1 0.020
D1043.1 Protein D1043.1 0.020
mcd-1 Protein MCD-1 0.020
msh-6 Protein MSH-6 0.020
fcd-2 Protein FCD-2 0.020
C18F10.7 Protein C18F10.7 0.019
F54D12.4 Protein F54D12.4 0.019
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Danio rerio
Name Description Probability Func Analog Organism
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.943
fancl Fanconi anemia, complementation group L 0.670
ung uracil-DNA glycosylase 0.260
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.157
brca2 breast cancer 2, early onset 0.130
gpia glucose phosphate isomerase a 0.120
pcna proliferating cell nuclear antigen 0.114
brip1 BRCA1 interacting protein C-terminal helicase 1 0.081
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.080
piwil1 piwi-like 1 (Drosophila) 0.071
eomesa eomesodermin homolog a 0.068
mybl2 myeloblastosis oncogene-like 2 0.063
tdrd1 tudor domain containing 1 0.056
mapk3 mitogen-activated protein kinase 3 0.050
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.045
asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 0.043
si:dkey-24g18.2 si:dkey-24g18.2 0.038
dync2i1 dynein, cytoplasmic 2, intermediate chain 1 0.038
mos v-mos Moloney murine sarcoma viral oncogene homolog 0.035
krcp kelch repeat-containing protein 0.032
tuba7l tubulin, alpha 7 like 0.032
pink1 PTEN induced putative kinase 1 0.031
msh2 mutS homolog 2 (E. coli) 0.030
ubr7 ubiquitin protein ligase E3 component n-recognin 7 0.030
LOC569642 hypothetical protein LOC569642 0.029
gro2 groucho 2 0.027
fanci Fanconi anemia, complementation group I 0.027
zgc:100817 zgc:100817 0.027
sycp3l synaptonemal complex protein 3 like 0.026
mtx1b metaxin 1b 0.026
h1m linker histone H1M 0.025
mlh1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) 0.025
nanos3 nanos homolog 3 0.024
vasa vasa homolog 0.024
crh corticotropin releasing hormone 0.024
buc bucky ball 0.023
syce2 synaptonemal complex central element protein 2 0.023
nme7 non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase) 0.023
si:ch211-215h6.2 si:ch211-215h6.2 0.022
gins2 GINS complex subunit 2 0.022
rfc4 replication factor C (activator 1) 4 0.022
dazl daz-like gene 0.021
pde6c phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.021
hormad1 HORMA domain containing 1 0.021
chek1 CHK1 checkpoint homolog (S. pombe) 0.020
piwil2 piwi-like 2 (Drosophila) 0.020
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.019
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.019
gria2a glutamate receptor, ionotropic, AMPA 2a 0.019
fmr1 fragile X mental retardation 1 0.019
rp2 retinitis pigmentosa 2 (X-linked recessive) 0.019
abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.018
aplp2 amyloid beta (A4) precursor-like protein 2 0.018
ca15b carbonic anhydrase XV b 0.018
zgc:55448 zgc:55448 0.018
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.018
zgc:92648 zgc:92648 0.018
zgc:101080 zgc:101080 0.018
LOC569768 metabotropic glutamate receptor 8-like 0.018
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.018
sinup siaz-interacting nuclear protein 0.017
LOC796298 isotocin receptor-like 1 0.017
pikfyve phosphoinositide kinase, FYVE finger containing 0.017
slc25a14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.017
pcbp2 poly(rC) binding protein 2 0.017
spsb1 splA/ryanodine receptor domain and SOCS box containing 1 0.016
foxo3a forkhead box O3A 0.016
faf2 Fas associated factor family member 2 0.016
ptpra protein tyrosine phosphatase, receptor type, A 0.016
palb2 partner and localizer of BRCA2 0.016
npepl1 aminopeptidase-like 1 0.016
pcdh7 protocadherin 7 0.016
bactin1 bactin1 0.016
prim1 primase polypeptide 1 0.016
igf1rb insulin-like growth factor 1b receptor 0.015
pvrl1b poliovirus receptor-related 1b 0.015
LOC570775 protein argonaute-1-like 0.015
ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1 0.015
ogt.2 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2 0.015
ythdf1 YTH domain family, member 1 0.015
ugt2a6 UDP glucuronosyltransferase 2 family, polypeptide A6 0.014
esco2 establishment of cohesion 1 homolog 2 0.014
apaf1 apoptotic protease activating factor 1 0.014
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.014
dynll2a dynein, light chain, LC8-type 2a 0.014
ube4b ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) 0.014
cdk5 cyclin-dependent protein kinase 5 0.014
appa amyloid beta (A4) precursor protein a 0.014
nedd1 neural precursor cell expressed, developmentally down-regulated 1 0.014
cacnb2b calcium channel, voltage-dependent, beta 2b 0.014
tmem110 transmembrane protein 110 0.014
snf8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.013
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.013
mycbp2 MYC binding protein 2 0.013
opa3 optic atrophy 3 0.013
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.013
rnf17 ring finger protein 17 0.013
LOC100001530 isotocin receptor-like 2 0.013
zgc:91813 zgc:91813 0.013
ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa 0.012
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Smc1a structural maintenance of chromosomes 1A 0.997
Ccna2 cyclin A2 0.983
Ccnb1 cyclin B1 0.956
H2afx H2A histone family, member X 0.880
Smc1b structural maintenance of chromosomes 1B 0.879
Smc3 structural maintenace of chromosomes 3 0.851
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.824
Stag3 stromal antigen 3 0.799
Rrm1 ribonucleotide reductase M1 0.796
Nde1 nuclear distribution gene E homolog 1 (A nidulans) 0.789
Smc2 structural maintenance of chromosomes 2 0.765
2410076I21Rik RIKEN cDNA 2410076I21 gene 0.752
Neurl1a neuralized homolog 1A (Drosophila) 0.715
Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) 0.701
Kif20a kinesin family member 20A 0.645
Prim2 DNA primase, p58 subunit 0.631
Prim1 DNA primase, p49 subunit 0.602
C330027C09Rik RIKEN cDNA C330027C09 gene 0.567
Ccne1 cyclin E1 0.557
Prc1 protein regulator of cytokinesis 1 0.547
Rec8 REC8 homolog (yeast) 0.547
Kif11 kinesin family member 11 0.520
Mecp2 methyl CpG binding protein 2 0.509
Hells helicase, lymphoid specific 0.487
Topbp1 topoisomerase (DNA) II binding protein 1 0.477
Zc3hc1 zinc finger, C3HC type 1 0.436
Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.416
Trap1a tumor rejection antigen P1A 0.357
Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.356
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.350
Cdca5 cell division cycle associated 5 0.349
Tacc3 transforming, acidic coiled-coil containing protein 3 0.336
Rrm2 ribonucleotide reductase M2 0.330
Racgap1 Rac GTPase-activating protein 1 0.309
Brca2 breast cancer 2 0.304
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.300
Nbn nibrin 0.294
Birc5 baculoviral IAP repeat-containing 5 0.289
Pola1 polymerase (DNA directed), alpha 1 0.283
Rfc3 replication factor C (activator 1) 3 0.280
Pcna proliferating cell nuclear antigen 0.276
Top2a topoisomerase (DNA) II alpha 0.270
Ddx4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.269
Vrk1 vaccinia related kinase 1 0.267
Fbxo15 F-box protein 15 0.254
Ints9 integrator complex subunit 9 0.251
Plk4 polo-like kinase 4 (Drosophila) 0.250
Tmpo thymopoietin 0.249
Tulp2 tubby-like protein 2 0.243
Ccnb2 cyclin B2 0.238
Serinc1 serine incorporator 1 0.233
Rfc1 replication factor C (activator 1) 1 0.229
Rpa2 replication protein A2 0.224
Zfp42 zinc finger protein 42 0.220
Kif23 kinesin family member 23 0.218
Anln anillin, actin binding protein 0.217
Ncaph non-SMC condensin I complex, subunit H 0.212
Nasp nuclear autoantigenic sperm protein (histone-binding) 0.210
Bub1 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) 0.210
Ckap2 cytoskeleton associated protein 2 0.207
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.204
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.203
Fanci Fanconi anemia, complementation group I 0.202
D1Pas1 DNA segment, Chr 1, Pasteur Institute 1 0.192
Ube2t ubiquitin-conjugating enzyme E2T (putative) 0.183
Aurka aurora kinase A 0.180
Ppih peptidyl prolyl isomerase H 0.176
Sycp2 synaptonemal complex protein 2 0.175
Stk31 serine threonine kinase 31 0.171
Zfand5 zinc finger, AN1-type domain 5 0.170
Rnf11 ring finger protein 11 0.168
Rnf17 ring finger protein 17 0.162
Rad21l RAD21-like (S. pombe) 0.161
Nr0b1 nuclear receptor subfamily 0, group B, member 1 0.157
Dmc1 DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) 0.146
Blm Bloom syndrome, RecQ helicase-like 0.142
Fmr1nb fragile X mental retardation 1 neighbor 0.139
Tipin timeless interacting protein 0.138
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.137
Tex19.1 testis expressed gene 19.1 0.126
Exo1 exonuclease 1 0.125
Mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.125
Rfc4 replication factor C (activator 1) 4 0.124
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.120
Cenph centromere protein H 0.120
Ldhc lactate dehydrogenase C 0.120
Brca1 breast cancer 1 0.119
Rad50 RAD50 homolog (S. cerevisiae) 0.118
Rpa3 replication protein A3 0.117
Nanog Nanog homeobox 0.117
Tex14 testis expressed gene 14 0.112
Cks2 CDC28 protein kinase regulatory subunit 2 0.111
Rbmy1a1 RNA binding motif protein, Y chromosome, family 1, member A1 0.108
Aurkb aurora kinase B 0.104
Tsc2 tuberous sclerosis 2 0.103
Dazl deleted in azoospermia-like 0.100
Csnk1g2 casein kinase 1, gamma 2 0.100
Taf7l TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.097
Ttk Ttk protein kinase 0.097
A930001N09Rik RIKEN cDNA A930001N09 gene 0.095
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Rattus norvegicus
Name Description Probability Func Analog Organism