The network for 'positive regulation of apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of apoptotic process

Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HYP2 Hyp2p 0.217
DNM1 Dnm1p 0.113
NBP2 Nbp2p 0.088
DCS2 Dcs2p 0.073
GUT2 Gut2p 0.073
TEF2 Tef2p 0.062
SMP1 Smp1p 0.058
IKI1 Iki1p 0.056
STI1 Sti1p 0.056
NDE1 Nde1p 0.056
HSL1 Hsl1p 0.054
THO2 Tho2p 0.053
HAL5 Hal5p 0.052
YLR257W hypothetical protein 0.051
PMT3 Pmt3p 0.050
ATG4 Atg4p 0.049
HOP1 Hop1p 0.048
PSP2 Psp2p 0.048
CMP2 Cmp2p 0.047
HDA2 Hda2p 0.047
EPL1 Epl1p 0.044
HCH1 Hch1p 0.044
RPL10 Rpl10p 0.044
PKC1 Pkc1p 0.044
PBS2 Pbs2p 0.043
HOG1 Hog1p 0.043
UPS3 Ups3p 0.043
STE7 Ste7p 0.042
RPS5 Rps5p 0.042
ROD1 Rod1p 0.042
CDC34 Cdc34p 0.041
MDH1 Mdh1p 0.041
AHP1 Ahp1p 0.041
GAD1 Gad1p 0.039
CCP1 Ccp1p 0.039
PET9 Pet9p 0.039
TEF1 Tef1p 0.039
ZDS1 Zds1p 0.039
CPR1 Cpr1p 0.038
BDH1 Bdh1p 0.038
BFR1 Bfr1p 0.038
UFO1 Ufo1p 0.037
YJU3 Yju3p 0.037
VMA13 Vma13p 0.037
RTS1 Rts1p 0.037
IDH2 Idh2p 0.037
SLX9 Slx9p 0.037
PBP1 Pbp1p 0.036
HOR7 Hor7p 0.036
GPH1 Gph1p 0.036
LTV1 Ltv1p 0.036
RCK1 Rck1p 0.036
CMD1 Cmd1p 0.036
MAS1 Mas1p 0.035
HHT2 Hht2p 0.035
YAP1802 hypothetical protein 0.035
HSP60 Hsp60p 0.035
IZH3 Izh3p 0.035
TPD3 Tpd3p 0.035
CDC4 Cdc4p 0.034
DIA2 Dia2p 0.034
HUG1 Hug1p 0.034
YKU70 Yku70p 0.034
SDH1 Sdh1p 0.034
HSP78 Hsp78p 0.034
ERR3 Err3p 0.034
SHY1 Shy1p 0.033
ENT2 Ent2p 0.033
STV1 Stv1p 0.033
RAD16 Rad16p 0.033
RLM1 Rlm1p 0.033
SLT2 Slt2p 0.033
ZEO1 Zeo1p 0.032
YPL088W hypothetical protein 0.032
MIR1 Mir1p 0.032
ENB1 Enb1p 0.032
RPS6B Rps6bp 0.032
SGE1 Sge1p 0.031
SSL2 Ssl2p 0.031
OLA1 Ola1p 0.031
OCH1 Och1p 0.031
MSG5 Msg5p 0.031
SOD1 Sod1p 0.031
MDM32 Mdm32p 0.031
ALD6 Ald6p 0.031
CAM1 Cam1p 0.031
BIT61 Bit61p 0.031
SIT1 Sit1p 0.031
RHO1 Rho1p 0.031
SKO1 Sko1p 0.030
BCH1 Bch1p 0.030
CKA1 Cka1p 0.030
YLR143W hypothetical protein 0.030
ATP14 Atp14p 0.029
PGM2 Pgm2p 0.029
HOR2 Hor2p 0.029
MDM34 Mdm34p 0.029
ECM30 Ecm30p 0.029
TRA1 Tra1p 0.029
RPL8A Rpl8ap 0.029
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.240
hsp-1 Protein HSP-1 0.109
inx-3 Protein INX-3 0.070
fkh-2 Protein FKH-2 0.053
daf-3 Protein DAF-3 0.053
nhr-2 Protein NHR-2 0.052
pry-1 Protein PRY-1 0.048
cnd-1 Protein CND-1 0.046
ceh-20 Protein CEH-20 0.044
imb-2 Protein IMB-2 0.043
zyg-1 Protein ZYG-1 0.041
bar-1 Protein BAR-1 0.041
sem-5 Protein SEM-5 0.039
rps-5 Protein RPS-5 0.038
Y65B4BR.5 Protein Y65B4BR.5 0.038
rla-0 Protein RLA-0 0.038
cst-2 Protein CST-2 0.034
rpl-12 Protein RPL-12 0.034
rpl-18 Protein RPL-18 0.032
lmn-1 Protein LMN-1 0.032
flt-1 Protein FLT-1 0.032
rpl-7 Protein RPL-7 0.031
inf-1 Protein INF-1 0.030
ten-1 Protein TEN-1 0.029
rpl-6 Protein RPL-6 0.028
ced-3 Protein CED-3 0.028
rhi-1 Protein RHI-1 0.028
cst-1 Protein CST-1 0.027
par-5 Protein PAR-5 0.026
eor-1 Protein EOR-1 0.025
rps-2 Protein RPS-2 0.025
egl-46 Protein EGL-46 0.024
htz-1 Protein HTZ-1 0.024
eps-8 Protein EPS-8 0.023
cam-1 Protein CAM-1 0.023
gpb-2 Protein GPB-2 0.023
arrd-13 Protein ARRD-13 0.023
pal-1 Protein PAL-1 0.021
rpl-15 Protein RPL-15 0.021
soc-2 Protein SOC-2 0.021
elt-6 Protein ELT-6 0.021
trim-9 Protein TRIM-9 0.020
lin-25 Protein LIN-25 0.019
kle-2 Protein KLE-2 0.019
atp-2 Protein ATP-2 0.019
plp-1 Protein PLP-1 0.019
egl-5 Protein EGL-5 0.018
tol-1 Protein TOL-1 0.018
rpt-3 Protein RPT-3 0.018
T28A8.4 Protein T28A8.4 0.018
zyg-11 Protein ZYG-11 0.018
let-19 Protein LET-19 0.017
F36D4.5 Protein F36D4.5 0.017
rpl-16 Protein RPL-16 0.017
unc-73 Protein UNC-73 0.017
T09B4.5 Protein T09B4.5 0.017
eef-1G Protein EEF-1G 0.017
clic-1 Protein CLIC-1 0.017
act-4 Protein ACT-4 0.016
acs-4 Protein ACS-4 0.016
F57B7.2 Protein F57B7.2 0.016
eef-1B.1 Protein EEF-1B.1 0.016
jmjd-1.2 Protein JMJD-1.2 0.016
wago-4 Protein WAGO-4 0.016
sma-6 Protein SMA-6 0.016
unc-9 Protein UNC-9 0.016
pbs-3 Protein PBS-3 0.016
cul-2 Protein CUL-2 0.016
atg-18 Protein ATG-18 0.015
dys-1 Protein DYS-1 0.015
vav-1 Protein VAV-1 0.015
elc-1 Protein ELC-1 0.015
pde-4 Protein PDE-4 0.015
C05D11.7 Protein C05D11.7 0.015
crt-1 Protein CRT-1 0.015
T28C6.7 Protein T28C6.7 0.015
rps-7 Protein RPS-7 0.015
egl-30 Protein EGL-30 0.015
rpl-25.2 Protein RPL-25.2 0.015
act-3 Protein ACT-3 0.015
unc-40 Protein UNC-40 0.014
let-756 Protein LET-756 0.014
F59A3.4 Protein F59A3.4 0.014
rpl-4 Protein RPL-4 0.014
smf-2 Protein SMF-2 0.014
slo-1 Protein SLO-1 0.014
tbb-2 Protein TBB-2 0.014
sna-2 Protein SNA-2 0.014
rla-1 Protein RLA-1 0.014
F31C3.2 Protein F31C3.2 0.014
imp-2 Protein IMP-2 0.014
rpl-5 Protein RPL-5 0.014
let-60 Protein LET-60 0.014
cra-1 Protein CRA-1 0.014
CELE_W02D7.6 Protein W02D7.6 0.013
cgef-1 Protein CGEF-1 0.013
F35G12.12 Protein F35G12.12 0.013
pmk-1 Protein PMK-1 0.013
clk-2 Protein CLK-2 0.013
cin-4 Protein CIN-4 0.013
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Danio rerio
Name Description Probability Func Analog Organism
bmp2b bone morphogenetic protein 2b 0.939
tbx1 T-box 1 0.758
bbc3 BCL2 binding component 3 0.648
itgb1b.2 integrin, beta 1b.2 0.588
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.487
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.470
alcama activated leukocyte cell adhesion molecule a 0.442
col1a1a collagen, type I, alpha 1a 0.346
igfbp3 insulin-like growth factor binding protein 3 0.345
frem3 Fras1 related extracellular matrix 3 0.316
dcc deleted in colorectal carcinoma 0.315
gli1 GLI-Kruppel family member 1 0.298
baxa bcl2-associated X protein, a 0.276
rarga retinoic acid receptor gamma a 0.250
robo3 roundabout homolog 3 0.250
hoxa13b homeo box A13b 0.245
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.245
foxo3b forkhead box O3b 0.240
mcl1a myeloid cell leukemia sequence 1a 0.236
sox11a SRY-box containing gene 11a 0.230
adrb2a adrenergic receptor, beta 2a 0.229
egr1 early growth response 1 0.229
neurod4 neurogenic differentiation 4 0.224
epas1b endothelial PAS domain protein 1b 0.224
ctsl1b cathepsin L, 1 b 0.215
bad BCL2-antagonist of cell death 0.201
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.193
hand2 heart and neural crest derivatives expressed transcript 2 0.193
notch1a notch homolog 1a 0.190
dlx5a distal-less homeobox gene 5a 0.190
inhbaa inhibin, beta Aa 0.186
csnk1da casein kinase 1, delta a 0.180
pea3 ETS-domain transcription factor pea3 0.179
bcl2l10 BCL2-like 10 (apoptosis facilitator) 0.179
bmp4 bone morphogenetic protein 4 0.173
hoxd4a homeo box D4a 0.173
cxcr4b chemokine (C-X-C motif), receptor 4b 0.172
nf1a neurofibromin 1a 0.161
cx43 connexin 43 0.157
klf4a Kruppel-like transcription factor 4a 0.157
bida BH3 interacting domain death agonist 0.154
rpsa ribosomal protein SA 0.146
mych myelocytomatosis oncogene homolog 0.141
bactin1 bactin1 0.136
bcl2l1 bcl2-like 1 0.126
vegfab vascular endothelial growth factor Ab 0.124
id1 inhibitor of DNA binding 1 0.122
mdm2 transformed 3T3 cell double minute 2 homolog (mouse) 0.120
evpl envoplakin 0.117
ch25hl1.1 cholesterol 25-hydroxylase like 1, member 1 0.116
fgfr1a fibroblast growth factor receptor 1a 0.115
osr1 odd-skipped related 1 (Drosophila) 0.114
hgfb hepatocyte growth factor b 0.113
tbx5a T-box 5a 0.112
plxnb2a plexin b2a 0.111
hoxa4a homeo box A4a 0.111
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.109
fn1 fibronectin 1 0.107
dlx4a distal-less homeobox gene 4a 0.103
cmyb transcription factor cmyb 0.102
hoxd11a homeo box D11a 0.101
hmgb1a high-mobility group box 1a 0.101
sox9a SRY-box containing gene 9a 0.098
tgfb2 transforming growth factor, beta 2 0.097
zgc:55813 zgc:55813 0.097
pabpc1a poly A binding protein, cytoplasmic 1 a 0.096
ahr2 aryl hydrocarbon receptor 2 0.095
pycard PYD and CARD domain containing 0.095
fgfr3 fibroblast growth factor receptor 3 0.093
mmp2 matrix metalloproteinase 2 0.089
sf3b1 splicing factor 3b, subunit 1 0.086
meis1 myeloid ecotropic viral integration 1 0.085
col10a1 collagen, type X, alpha 1 0.081
hoxa11b homeo box A11b 0.080
apoeb apolipoprotein Eb 0.080
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.079
ins preproinsulin 0.079
gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.079
th tyrosine hydroxylase 0.078
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.078
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.078
enc1 ectodermal-neural cortex (with BTB-like domain) 0.077
tgfb3 transforming growth factor, beta 3 0.074
ccng2 cyclin G2 0.074
junb jun B proto-oncogene 0.074
fstl1b follistatin-like 1b 0.074
smad7 MAD, mothers against decapentaplegic homolog 7 (Drosophila) 0.073
gpr126 G protein-coupled receptor 126 0.073
nrp2b neuropilin 2b 0.073
acvr2b activin receptor IIb 0.072
clu clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) 0.072
pccb propionyl Coenzyme A carboxylase, beta polypeptide 0.071
satb2 SATB homeobox 2 0.068
runx2a runt-related transcription factor 2a 0.067
caspa caspase a 0.066
rhoab ras homolog gene family, member Ab 0.066
spry4 sprouty (Drosophila) homolog 4 0.064
fmr1 fragile X mental retardation 1 0.064
igf1rb insulin-like growth factor 1b receptor 0.064
fgf10a fibroblast growth factor 10a 0.063
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
slmb supernumerary limbs 0.626
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.593
Rac1 CG2248 gene product from transcript CG2248-RA 0.538
Atg1 Autophagy-specific gene 1 0.424
wg wingless 0.394
Myb Myb oncogene-like 0.335
nej nejire 0.333
S6k RPS6-p70-protein kinase 0.315
Ras85D Ras oncogene at 85D 0.265
Egfr Epidermal growth factor receptor 0.248
robo roundabout 0.240
slpr slipper 0.239
Src42A Src oncogene at 42A 0.217
ed echinoid 0.182
car carnation 0.178
G-salpha60A G protein salpha 60A 0.164
Atpalpha Na pump alpha subunit 0.164
brk brinker 0.159
beta-Spec beta Spectrin 0.144
gig gigas 0.140
Rbf Retinoblastoma-family protein 0.139
InR Insulin-like receptor 0.137
sd scalloped 0.137
CG11347 CG11347 gene product from transcript CG11347-RE 0.131
drk downstream of receptor kinase 0.130
kay kayak 0.122
gro groucho 0.103
th thread 0.103
ex expanded 0.101
shn schnurri 0.099
park parkin 0.096
Fmr1 CG6203 gene product from transcript CG6203-RC 0.095
Lis-1 Lissencephaly-1 0.093
Tak1 TGF-beta activated kinase 1 0.092
Akt1 CG4006 gene product from transcript CG4006-RA 0.092
debcl death executioner Bcl-2 homologue 0.092
rno rhinoceros 0.091
Stim Stromal interaction molecule 0.091
Moe Moesin 0.091
p53 CG33336 gene product from transcript CG33336-RB 0.084
aop anterior open 0.078
Tab2 TAK1-associated binding protein 2 0.078
bchs blue cheese 0.074
dm diminutive 0.074
Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE 0.073
Dcp-1 Death caspase-1 0.073
jar jaguar 0.073
Sdc Syndecan 0.072
Pten CG5671 gene product from transcript CG5671-RB 0.070
Slip1 CG1783 gene product from transcript CG1783-RA 0.069
Pli Pellino 0.068
jing CG9397 gene product from transcript CG9397-RI 0.068
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.067
Fhos CG42610 gene product from transcript CG42610-RC 0.067
baz bazooka 0.066
Ptp69D Protein tyrosine phosphatase 69D 0.065
Atg13 Autophagy-specific gene 13 0.064
Wnt2 Wnt oncogene analog 2 0.064
scb scab 0.064
Atg6 Autophagy-specific gene 6 0.063
hep hemipterous 0.062
dco discs overgrown 0.061
Csp Cysteine string protein 0.061
usp ultraspiracle 0.060
key kenny 0.059
CG10984 CG10984 gene product from transcript CG10984-RC 0.059
Dad Daughters against dpp 0.058
loqs loquacious 0.058
shg shotgun 0.057
CG10267 CG10267 gene product from transcript CG10267-RB 0.056
Dp DP transcription factor 0.056
sim single-minded 0.055
flw flapwing 0.054
BG4 CG12297 gene product from transcript CG12297-RA 0.054
imd immune deficiency 0.053
asf1 anti-silencing factor 1 0.052
Dredd Death related ced-3/Nedd2-like protein 0.052
fs(2)ltoPP43 female sterile (2) ltoPP43 0.051
mys myospheroid 0.051
HtrA2 CG8464 gene product from transcript CG8464-RA 0.050
CG6412 CG6412 gene product from transcript CG6412-RA 0.050
kel kelch 0.050
CG11267 CG11267 gene product from transcript CG11267-RA 0.049
rut rutabaga 0.049
milt milton 0.049
nkd naked cuticle 0.048
mask multiple ankyrin repeats single KH domain 0.048
mge maggie 0.048
caz cabeza 0.048
kn knot 0.048
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.048
Rel Relish 0.047
zfh2 Zn finger homeodomain 2 0.046
rpr reaper 0.046
Rac2 CG8556 gene product from transcript CG8556-RA 0.045
spas spastin 0.045
LanB2 Laminin B2 0.045
egr eiger 0.045
Kr Kruppel 0.045
numb CG3779 gene product from transcript CG3779-RB 0.044
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.000
CREBBP CREB binding protein 1.000
BCL2 B-cell CLL/lymphoma 2 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.999
MAPK14 mitogen-activated protein kinase 14 0.999
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.997
FAS Fas (TNF receptor superfamily, member 6) 0.996
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.994
MAPK1 mitogen-activated protein kinase 1 0.994
SMAD3 SMAD family member 3 0.994
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.994
EGFR epidermal growth factor receptor 0.993
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.992
DUSP1 dual specificity phosphatase 1 0.992
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.992
ESR1 estrogen receptor 1 0.991
CAV1 caveolin 1, caveolae protein, 22kDa 0.990
AR androgen receptor 0.989
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.989
FHL2 four and a half LIM domains 2 0.988
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.987
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.982
EP300 E1A binding protein p300 0.981
SQSTM1 sequestosome 1 0.977
BIRC3 baculoviral IAP repeat containing 3 0.971
CFLAR CASP8 and FADD-like apoptosis regulator 0.970
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.970
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.970
FADD Fas (TNFRSF6)-associated via death domain 0.962
JUN jun proto-oncogene 0.960
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.960
MAPK8 mitogen-activated protein kinase 8 0.953
XIAP X-linked inhibitor of apoptosis 0.950
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.948
BCL2L1 BCL2-like 1 0.943
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.943
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.939
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.934
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.930
BID BH3 interacting domain death agonist 0.929
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.929
TRAF3 TNF receptor-associated factor 3 0.926
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.917
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.916
RB1 retinoblastoma 1 0.911
PTEN phosphatase and tensin homolog 0.910
LRRK2 leucine-rich repeat kinase 2 0.910
BAD BCL2-associated agonist of cell death 0.906
CDK2 cyclin-dependent kinase 2 0.905
NCOA3 nuclear receptor coactivator 3 0.902
RXRA retinoid X receptor, alpha 0.900
SMAD1 SMAD family member 1 0.898
MAPK3 mitogen-activated protein kinase 3 0.897
APP amyloid beta (A4) precursor protein 0.893
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.888
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.881
ATF3 activating transcription factor 3 0.873
BAX BCL2-associated X protein 0.871
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.851
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.849
GSK3B glycogen synthase kinase 3 beta 0.845
RARA retinoic acid receptor, alpha 0.843
CCR5 chemokine (C-C motif) receptor 5 0.829
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.827
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.811
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.808
UBC ubiquitin C 0.805
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.803
C1QA complement component 1, q subcomponent, A chain 0.803
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.800
CCL5 chemokine (C-C motif) ligand 5 0.800
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.798
ANXA1 annexin A1 0.790
SMAD7 SMAD family member 7 0.790
SP1 Sp1 transcription factor 0.787
DAXX death-domain associated protein 0.784
RIPK2 receptor-interacting serine-threonine kinase 2 0.780
CXCL9 chemokine (C-X-C motif) ligand 9 0.778
TXN thioredoxin 0.772
S100B S100 calcium binding protein B 0.769
THBS1 thrombospondin 1 0.768
TRAF1 TNF receptor-associated factor 1 0.766
MAP2K4 mitogen-activated protein kinase kinase 4 0.749
TRAF2 TNF receptor-associated factor 2 0.739
CCL4 chemokine (C-C motif) ligand 4 0.729
HTT huntingtin 0.722
S100A6 S100 calcium binding protein A6 0.720
HCK hemopoietic cell kinase 0.717
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.714
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.712
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.702
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.697
PML promyelocytic leukemia 0.695
SETDB1 SET domain, bifurcated 1 0.682
BIRC2 baculoviral IAP repeat containing 2 0.681
SH2D1A SH2 domain containing 1A 0.674
NCOR1 nuclear receptor corepressor 1 0.672
SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 0.666
NCOA1 nuclear receptor coactivator 1 0.661
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Pten phosphatase and tensin homolog 1.000
Tnf tumor necrosis factor 0.996
Fgfr2 fibroblast growth factor receptor 2 0.993
Ctnnb1 catenin (cadherin associated protein), beta 1 0.985
Gli3 GLI-Kruppel family member GLI3 0.985
Fgfr1 fibroblast growth factor receptor 1 0.984
Mapk14 mitogen-activated protein kinase 14 0.983
Apc adenomatosis polyposis coli 0.979
Bcl2 B-cell leukemia/lymphoma 2 0.979
Ncoa3 nuclear receptor coactivator 3 0.974
Fas Fas (TNF receptor superfamily member 6) 0.973
Smad3 MAD homolog 3 (Drosophila) 0.972
Tgfb2 transforming growth factor, beta 2 0.967
Tgfb1 transforming growth factor, beta 1 0.965
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.961
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.950
En1 engrailed 1 0.949
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.949
Lep leptin 0.948
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.946
Nos2 nitric oxide synthase 2, inducible 0.944
Shh sonic hedgehog 0.942
Pax6 paired box gene 6 0.941
Mdm2 transformed mouse 3T3 cell double minute 2 0.940
Alx4 aristaless-like homeobox 4 0.937
Bmp4 bone morphogenetic protein 4 0.936
Fos FBJ osteosarcoma oncogene 0.935
Cd44 CD44 antigen 0.935
Atm ataxia telangiectasia mutated homolog (human) 0.925
Runx2 runt related transcription factor 2 0.924
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.917
Gli2 GLI-Kruppel family member GLI2 0.916
Rb1 retinoblastoma 1 0.912
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.904
Mapk8 mitogen-activated protein kinase 8 0.901
Neurod1 neurogenic differentiation 1 0.894
Ptgs2 prostaglandin-endoperoxide synthase 2 0.875
Pparg peroxisome proliferator activated receptor gamma 0.868
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.867
Mdm4 transformed mouse 3T3 cell double minute 4 0.867
Hoxd13 homeobox D13 0.859
Ren1 renin 1 structural 0.859
Emx1 empty spiracles homolog 1 (Drosophila) 0.859
Jun Jun oncogene 0.852
Rara retinoic acid receptor, alpha 0.851
Notch1 Notch gene homolog 1 (Drosophila) 0.827
Lepr leptin receptor 0.823
Igh immunoglobulin heavy chain complex 0.812
Hif1a hypoxia inducible factor 1, alpha subunit 0.805
Sfrp2 secreted frizzled-related protein 2 0.804
Notch2 Notch gene homolog 2 (Drosophila) 0.801
App amyloid beta (A4) precursor protein 0.796
Sox2 SRY-box containing gene 2 0.793
Tgfbr1 transforming growth factor, beta receptor I 0.792
Foxc1 forkhead box C1 0.790
S1pr2 sphingosine-1-phosphate receptor 2 0.779
Lyz2 lysozyme 2 0.768
Fshr follicle stimulating hormone receptor 0.767
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.763
E2f1 E2F transcription factor 1 0.761
Klf4 Kruppel-like factor 4 (gut) 0.757
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.756
Mef2d myocyte enhancer factor 2D 0.751
Nf1 neurofibromatosis 1 0.750
Fcgr2b Fc receptor, IgG, low affinity IIb 0.736
Rarg retinoic acid receptor, gamma 0.732
Gdnf glial cell line derived neurotrophic factor 0.732
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.730
Kit kit oncogene 0.723
Csf1 colony stimulating factor 1 (macrophage) 0.718
Pkd1 polycystic kidney disease 1 homolog 0.712
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.709
Nos3 nitric oxide synthase 3, endothelial cell 0.706
Jak2 Janus kinase 2 0.706
Lef1 lymphoid enhancer binding factor 1 0.705
Otx2 orthodenticle homolog 2 (Drosophila) 0.704
Mcl1 myeloid cell leukemia sequence 1 0.702
Rxra retinoid X receptor alpha 0.702
Zeb1 zinc finger E-box binding homeobox 1 0.700
Egr1 early growth response 1 0.700
Traf6 TNF receptor-associated factor 6 0.699
Wnt6 wingless-related MMTV integration site 6 0.699
Vegfa vascular endothelial growth factor A 0.691
Foxf1a forkhead box F1a 0.686
Gsk3b glycogen synthase kinase 3 beta 0.686
Smad7 MAD homolog 7 (Drosophila) 0.679
Prrx1 paired related homeobox 1 0.679
Zfp36 zinc finger protein 36 0.678
Prrx2 paired related homeobox 2 0.672
Ar androgen receptor 0.670
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.662
Prlr prolactin receptor 0.662
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.660
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.660
Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) 0.657
Lrrk2 leucine-rich repeat kinase 2 0.655
Egfr epidermal growth factor receptor 0.650
Ptch1 patched homolog 1 0.649
Drd2 dopamine receptor D2 0.649
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Fos FBJ osteosarcoma oncogene 0.950
Anxa4 annexin A4 0.738
Egr1 early growth response 1 0.676
Anxa2 annexin A2 0.556
Socs3 suppressor of cytokine signaling 3 0.550
Zfp36 zinc finger protein 36 0.550
Ier2 immediate early response 2 0.508
Gna15 guanine nucleotide binding protein, alpha 15 0.479
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.475
Klf4 Kruppel-like factor 4 (gut) 0.459
Anxa5 annexin A5 0.441
S100a9 S100 calcium binding protein A9 0.428
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.427
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.399
Prkcg protein kinase C, gamma 0.379
Egr2 early growth response 2 0.366
Jun Jun oncogene 0.355
Btg2 BTG family, member 2 0.336
Junb jun B proto-oncogene 0.332
Cdc42 cell division cycle 42 (GTP binding protein) 0.330
Calcb calcitonin-related polypeptide, beta 0.329
Matk megakaryocyte-associated tyrosine kinase 0.310
Slit3 slit homolog 3 (Drosophila) 0.307
S100a10 S100 calcium binding protein A10 0.302
Casp3 caspase 3 0.294
Ppard peroxisome proliferator-activated receptor delta 0.292
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.289
Dnase1l3 deoxyribonuclease 1-like 3 0.272
Flt1 FMS-related tyrosine kinase 1 0.270
Arpc1b actin related protein 2/3 complex, subunit 1B 0.268
Efnb1 ephrin B1 0.267
S100a8 S100 calcium binding protein A8 0.261
Pgk1 phosphoglycerate kinase 1 0.246
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.237
Akp3 alkaline phosphatase 3, intestine, not Mn requiring 0.228
Neurod2 neurogenic differentiation 2 0.222
LOC24906 RoBo-1 0.220
Fgfr2 fibroblast growth factor receptor 2 0.218
Guca2a guanylate cyclase activator 2a (guanylin) 0.217
Agtr1a angiotensin II receptor, type 1a 0.212
Il8ra interleukin 8 receptor, alpha 0.212
Il8rb interleukin 8 receptor, beta 0.211
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.210
Vim vimentin 0.210
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.205
Ptprc protein tyrosine phosphatase, receptor type, C 0.205
Casp12 caspase 12 0.203
Ccl4 chemokine (C-C motif) ligand 4 0.203
Il6 interleukin 6 0.203
Dusp1 dual specificity phosphatase 1 0.200
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.199
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.199
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.198
Serpinb6a serine (or cysteine) peptidase inhibitor, clade B, member 6a 0.197
Il2rb interleukin 2 receptor, beta 0.195
Hoxa10 homeo box A10 0.195
Hck hemopoietic cell kinase 0.194
Jak2 Janus kinase 2 0.191
Adrb1 adrenergic, beta-1-, receptor 0.190
Gria2 glutamate receptor, ionotropic, AMPA 2 0.187
Rap1b RAP1B, member of RAS oncogene family 0.186
Casp1 caspase 1 0.180
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.179
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.179
LOC305103 cell surface glycoprotein gp42 0.177
Mmp7 matrix metallopeptidase 7 0.175
Grid1 glutamate receptor, ionotropic, delta 1 0.175
Ripk3 receptor-interacting serine-threonine kinase 3 0.174
Ifng interferon gamma 0.173
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.173
Vip vasoactive intestinal peptide 0.171
Ahsg alpha-2-HS-glycoprotein 0.168
Itgam integrin, alpha M 0.167
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.165
Tbxa2r thromboxane A2 receptor 0.165
Pebp1 phosphatidylethanolamine binding protein 1 0.163
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.163
Egfr epidermal growth factor receptor 0.161
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.158
Selp selectin P 0.157
C5ar1 complement component 5a receptor 1 0.154
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.154
Klf6 Kruppel-like factor 6 0.153
Alb albumin 0.152
Trim47 tripartite motif-containing 47 0.151
Mycs myc-like oncogene, s-myc protein 0.151
Add2 adducin 2 (beta) 0.145
Crip cysteine-rich intestinal protein 0.145
Cd151 CD151 molecule (Raph blood group) 0.144
Smad2 SMAD family member 2 0.143
Defb1 defensin beta 1 0.142
Rab13 RAB13, member RAS oncogene family 0.141
Pkm2 pyruvate kinase, muscle 0.140
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.140
Serpinb5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.138
Tacr1 tachykinin receptor 1 0.138
Lig3 ligase III, DNA, ATP-dependent 0.137
Rnf112 ring finger protein 112 0.137
Cd80 Cd80 molecule 0.137
Olr837 olfactory receptor 837 0.135