The network for 'regulation of actin cytoskeleton organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of actin cytoskeleton organization

Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MYO5 Myo5p 0.999
ACT1 Act1p 0.957
ABP1 Abp1p 0.846
SRV2 Srv2p 0.750
CDC24 Cdc24p 0.685
LSB1 Lsb1p 0.677
PBS2 Pbs2p 0.656
ARC15 Arc15p 0.552
ARP2 Arp2p 0.441
ARC35 Arc35p 0.417
SAC6 Sac6p 0.415
ARC40 Arc40p 0.415
BEM1 Bem1p 0.384
BBC1 Bbc1p 0.363
BNI1 Bni1p 0.361
SLA2 Sla2p 0.356
RVS167 Rvs167p 0.342
ARC19 Arc19p 0.307
SSK2 Ssk2p 0.293
TPM1 Tpm1p 0.286
SPA2 Spa2p 0.285
RHO1 Rho1p 0.278
TOR1 Tor1p 0.266
SSK1 Ssk1p 0.240
CAP2 Cap2p 0.206
MLC1 Mlc1p 0.205
PFY1 Pfy1p 0.192
GIC1 Gic1p 0.154
LAS17 Las17p 0.137
ROM2 Rom2p 0.132
TWF1 Twf1p 0.130
ARC18 Arc18p 0.116
BOI1 Boi1p 0.116
MKK1 Mkk1p 0.114
BZZ1 Bzz1p 0.106
KEL1 Kel1p 0.104
RDI1 Rdi1p 0.087
ENT2 Ent2p 0.076
ARP3 Arp3p 0.074
FKS1 Fks1p 0.073
BEM2 Bem2p 0.067
GYL1 Gyl1p 0.066
AVO1 Avo1p 0.061
CDC42 Cdc42p 0.056
PKC1 Pkc1p 0.056
PIN3 Pin3p 0.055
CDC25 Cdc25p 0.054
CAP1 Cap1p 0.053
AIP1 Aip1p 0.053
FUS1 Fus1p 0.052
CYK3 Cyk3p 0.049
MSB4 Msb4p 0.049
BEM4 Bem4p 0.047
CDC55 Cdc55p 0.046
BUD6 Bud6p 0.043
CLA4 Cla4p 0.039
PRS2 Prs2p 0.038
SSK22 Ssk22p 0.038
YSC84 Ysc84p 0.038
KOG1 Kog1p 0.037
SCP1 Scp1p 0.037
RIO2 Rio2p 0.035
RSR1 Rsr1p 0.035
GIP4 Gip4p 0.035
ZDS1 Zds1p 0.034
BEM3 Bem3p 0.034
SKT5 Skt5p 0.033
HOF1 Hof1p 0.033
STD1 Std1p 0.031
RRP14 Rrp14p 0.031
UGO1 Ugo1p 0.030
BNR1 Bnr1p 0.030
VRP1 Vrp1p 0.030
MDM32 Mdm32p 0.029
DNM1 Dnm1p 0.029
FAR1 Far1p 0.029
RGD1 Rgd1p 0.028
MKK2 Mkk2p 0.028
YPK1 Ypk1p 0.027
PPH21 Pph21p 0.027
COF1 Cof1p 0.027
MOB2 Mob2p 0.027
CAM1 Cam1p 0.026
YFR016C hypothetical protein 0.026
AIM3 Aim3p 0.026
IRA1 Ira1p 0.026
BOI2 Boi2p 0.025
BCK1 Bck1p 0.025
BUD2 Bud2p 0.025
MER1 Mer1p 0.024
BUD14 Bud14p 0.024
APP1 App1p 0.022
VPS17 Vps17p 0.022
DCP2 Dcp2p 0.022
BUL1 Bul1p 0.022
GIC2 Gic2p 0.022
YLR162W hypothetical protein 0.021
SUT1 Sut1p 0.021
PPH3 Pph3p 0.021
BSP1 Bsp1p 0.020
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.044
unc-45 Protein UNC-45 0.033
ina-1 Protein INA-1 0.032
cdc-42 Protein CDC-42 0.023
mig-38 Protein MIG-38 0.019
alp-1 Protein ALP-1 0.019
fhod-1 Protein FHOD-1 0.018
CELE_Y45F10B.13 Protein Y45F10B.13 0.017
unc-16 Protein UNC-16 0.017
fln-2 Protein FLN-2 0.016
unc-15 Protein UNC-15 0.016
T21B6.3 Protein T21B6.3 0.015
pha-4 Protein PHA-4 0.015
rab-5 Protein RAB-5 0.015
lat-1 Protein LAT-1 0.015
vab-1 Protein VAB-1 0.015
atf-7 Protein ATF-7 0.015
CELE_T04A8.7 Protein T04A8.7 0.014
goa-1 Protein GOA-1 0.014
ttm-4 Protein TTM-4 0.013
unc-43 Protein UNC-43 0.013
tni-1 Protein TNI-1 0.013
atn-1 Protein ATN-1 0.013
lir-1 Protein LIR-1 0.012
Y18H1A.2 Protein Y18H1A.2 0.012
soc-2 Protein SOC-2 0.012
praf-3 Protein PRAF-3 0.012
R03H10.2 Protein R03H10.2 0.012
CELE_W05H12.1 Protein W05H12.1 0.012
wip-1 Protein WIP-1 0.012
klp-3 Protein KLP-3 0.011
tag-232 Protein TAG-232 0.011
afd-1 Protein AFD-1 0.011
pat-12 Protein PAT-12 0.011
C09G1.4 Protein C09G1.4 0.011
CELE_B0238.10 Protein B0238.10 0.011
pry-1 Protein PRY-1 0.010
kal-1 Protein KAL-1 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cotl1 coactosin-like 1 (Dictyostelium) 0.573
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.519
tpm3 tropomyosin 3 0.463
smyd1b SET and MYND domain containing 1b 0.365
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.359
itgb3b integrin beta 3b 0.269
itgb1b.2 integrin, beta 1b.2 0.239
scinla scinderin like a 0.210
epb4.1l4 erythrocyte protein band 4.1-like 4 0.203
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.173
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.158
csrp1a cysteine and glycine-rich protein 1a 0.152
itgb1a integrin, beta 1a 0.148
bactin1 bactin1 0.140
si:ch73-60e21.1 si:ch73-60e21.1 0.124
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.118
klf2b Kruppel-like factor 2b 0.114
fgf3 fibroblast growth factor 3 0.113
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.100
zgc:100942 zgc:100942 0.097
krt8 keratin 8 0.077
snx12 sorting nexin 12 0.076
pfn1 profilin 1 0.073
pak2a p21 (CDKN1A)-activated kinase 2a 0.066
pikfyve phosphoinositide kinase, FYVE finger containing 0.055
actn1 actinin, alpha 1 0.052
hspg2 heparan sulfate proteoglycan 2 0.051
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.050
acvr1b activin A receptor, type IB 0.048
zgc:92360 zgc:92360 0.048
jup junction plakoglobin 0.046
tnnc1b troponin C type 1b (slow) 0.046
ryr3 ryanodine receptor 3 0.044
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.043
lims1 LIM and senescent cell antigen-like domains 1 0.043
msna moesin a 0.039
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.038
pdlim1 PDZ and LIM domain 1 (elfin) 0.038
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.038
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.037
smyd1a SET and MYND domain containing 1a 0.037
ckma creatine kinase, muscle a 0.036
alcamb activated leukocyte cell adhesion molecule b 0.035
smyhc1 slow myosin heavy chain 1 0.033
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.033
zbtb4 zinc finger and BTB domain containing 4 0.030
itgb1b.1 integrin, beta 1b.1 0.030
myod1 myogenic differentiation 1 0.030
plxnb2a plexin b2a 0.029
s100a10b S100 calcium binding protein A10b 0.029
zgc:153867 zgc:153867 0.029
rras related RAS viral (r-ras) oncogene homolog 0.029
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.028
dopey2 dopey family member 2 0.026
sulf2l sulfatase 2, like 0.026
dspa desmoplakin a 0.025
itgb1b integrin, beta 1b 0.025
tagln2 transgelin 2 0.024
nphs2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.024
smyd2b SET and MYND domain containing 2b 0.024
shroom4 shroom family member 4 0.023
LOC100151531 zinc finger protein Gfi-1b-like 0.023
btr30 bloodthirsty-related gene family, member 30 0.023
si:ch211-212m21.5 si:ch211-212m21.5 0.023
ef1a elongation factor 1-alpha 0.023
snf8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.023
mylz2 myosin, light polypeptide 2, skeletal muscle 0.022
arpc1b actin related protein 2/3 complex, subunit 1B 0.022
rab13 RAB13, member RAS oncogene family 0.022
celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.022
egfra epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) 0.022
myl9l myosin, light polypeptide 9, like 0.022
sema3fa semaphorin 3fa 0.022
vegfaa vascular endothelial growth factor Aa 0.022
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.021
flncb filamin C, gamma b (actin binding protein 280) 0.021
entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.021
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.020
arpc5b actin related protein 2/3 complex, subunit 5B 0.020
tnnt3b troponin T3b, skeletal, fast 0.020
rab5c RAB5C, member RAS oncogene family 0.020
kdrl kinase insert domain receptor like 0.020
zgc:101761 zgc:101761 0.019
ednra endothelin receptor type A 0.019
gnas GNAS complex locus 0.019
slit3 slit (Drosophila) homolog 3 0.019
tp63 tumor protein p63 0.018
ryr1b ryanodine receptor 1b (skeletal) 0.018
cnn2 calponin 2 0.018
thy1 Thy-1 cell surface antigen 0.018
pdlim5 PDZ and LIM domain 5 0.018
anxa2a annexin A2a 0.018
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.018
pvrl1b poliovirus receptor-related 1b 0.018
lrrc33 leucine rich repeat containing 33 0.018
pdlim4 PDZ and LIM domain 4 0.018
elovl1b elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b 0.018
gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.017
wdr1 WD repeat domain 1 0.017
pkp2 plakophilin 2 0.017
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
cindr CIN85 and CD2AP orthologue 0.969
chic chickadee 0.953
Rho1 CG8416 gene product from transcript CG8416-RB 0.938
WASp CG1520 gene product from transcript CG1520-RA 0.915
Cdc42 CG12530 gene product from transcript CG12530-RA 0.898
cpb capping protein beta 0.861
msn misshapen 0.851
Arp66B Actin-related protein 66B 0.848
usp ultraspiracle 0.781
trio CG18214 gene product from transcript CG18214-RA 0.780
Rac1 CG2248 gene product from transcript CG2248-RA 0.761
rok Rho-kinase 0.741
par-1 CG8201 gene product from transcript CG8201-RA 0.716
mbc myoblast city 0.704
katanin-60 katanin 60 0.635
shot short stop 0.605
Akt1 CG4006 gene product from transcript CG4006-RA 0.569
ena enabled 0.550
flw flapwing 0.502
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.476
bif bifocal 0.457
Rala Ras-related protein 0.450
pod1 CG4532 gene product from transcript CG4532-RF 0.450
hep hemipterous 0.447
Ras85D Ras oncogene at 85D 0.426
mbt mushroom bodies tiny 0.412
Caps Calcium activated protein for secretion 0.378
zip zipper 0.375
trc tricornered 0.370
aop anterior open 0.364
Vrp1 Verprolin 1 0.363
drpr draper 0.362
mys myospheroid 0.358
rhea CG6831 gene product from transcript CG6831-RA 0.349
CadN Cadherin-N 0.348
Cortactin CG3637 gene product from transcript CG3637-RA 0.347
flr flare 0.340
sqh spaghetti squash 0.298
stai stathmin 0.294
sls sallimus 0.285
twf twinfilin 0.280
bsk basket 0.273
fz frizzled 0.250
par-6 CG5884 gene product from transcript CG5884-RA 0.248
dsh dishevelled 0.239
Mtl Mig-2-like 0.239
drk downstream of receptor kinase 0.229
cpa capping protein alpha 0.225
CG8578 CG8578 gene product from transcript CG8578-RA 0.221
Ced-12 CG5336 gene product from transcript CG5336-RA 0.211
robo roundabout 0.203
Sop2 Suppressor of profilin 2 0.202
Actn alpha actinin 0.201
Cip4 CG15015 gene product from transcript CG15015-RA 0.198
robo3 CG5423 gene product from transcript CG5423-RA 0.185
egl egalitarian 0.184
stck steamer duck 0.167
Ephrin CG1862 gene product from transcript CG1862-RA 0.165
Act88F Actin 88F 0.156
egh egghead 0.155
baz bazooka 0.150
Pak3 CG14895 gene product from transcript CG14895-RA 0.150
jar jaguar 0.150
wdb widerborst 0.150
wun wunen 0.149
Mical Molecule interacting with CasL 0.146
mew multiple edematous wings 0.142
Lis-1 Lissencephaly-1 0.140
Dap160 Dynamin associated protein 160 0.138
CG10641 CG10641 gene product from transcript CG10641-RA 0.135
Vang Van Gogh 0.135
Arf51F ADP ribosylation factor 51F 0.135
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.134
wts warts 0.131
Ten-m Tenascin major 0.131
rst roughest 0.130
arm armadillo 0.126
G-oalpha47A G protein oalpha 47A 0.124
htl heartless 0.119
Apc APC-like 0.118
neur neuralized 0.117
Jra Jun-related antigen 0.117
ttk tramtrack 0.116
cher cheerio 0.115
numb CG3779 gene product from transcript CG3779-RB 0.114
shn schnurri 0.112
Rab5 Rab-protein 5 0.112
mts microtubule star 0.111
RhoGAP92B CG4755 gene product from transcript CG4755-RA 0.111
kst karst 0.111
Lasp CG3849 gene product from transcript CG3849-RB 0.109
Zasp52 Z band alternatively spliced PDZ-motif protein 52 0.108
tutl turtle 0.107
Mob2 CG11711 gene product from transcript CG11711-RC 0.107
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.105
CG6051 CG6051 gene product from transcript CG6051-RB 0.104
aPKC atypical protein kinase C 0.103
hbs hibris 0.102
sec6 CG5341 gene product from transcript CG5341-RA 0.099
X11L CG5675 gene product from transcript CG5675-RB 0.093
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
GRB2 growth factor receptor-bound protein 2 1.000
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
FLNA filamin A, alpha 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.999
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.999
FYN FYN oncogene related to SRC, FGR, YES 0.999
IQGAP1 IQ motif containing GTPase activating protein 1 0.998
EGFR epidermal growth factor receptor 0.997
MYH9 myosin, heavy chain 9, non-muscle 0.992
BAIAP2 BAI1-associated protein 2 0.992
FN1 fibronectin 1 0.990
ABI1 abl-interactor 1 0.989
RHOA ras homolog gene family, member A 0.988
SFN stratifin 0.987
ACTB actin, beta 0.987
GAS7 growth arrest-specific 7 0.979
CFL1 cofilin 1 (non-muscle) 0.977
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.976
DNM2 dynamin 2 0.975
ZYX zyxin 0.974
WASL Wiskott-Aldrich syndrome-like 0.972
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.968
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.960
VAV1 vav 1 guanine nucleotide exchange factor 0.957
NCK1 NCK adaptor protein 1 0.952
SH3KBP1 SH3-domain kinase binding protein 1 0.940
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.939
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.937
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.933
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.933
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.933
ITSN1 intersectin 1 (SH3 domain protein) 0.930
HCK hemopoietic cell kinase 0.927
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.923
S100A11 S100 calcium binding protein A11 0.923
S100A6 S100 calcium binding protein A6 0.906
ACTG1 actin, gamma 1 0.901
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.901
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.891
TPM4 tropomyosin 4 0.877
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.868
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.847
NCF2 neutrophil cytosolic factor 2 0.844
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.825
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.811
LMNA lamin A/C 0.810
SNX9 sorting nexin 9 0.799
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.795
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.754
PFN1 profilin 1 0.747
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.738
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.736
SOS1 son of sevenless homolog 1 (Drosophila) 0.735
SPRR2A small proline-rich protein 2A 0.733
LGALS1 lectin, galactoside-binding, soluble, 1 0.732
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.730
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.729
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.716
WIPF1 WAS/WASL interacting protein family, member 1 0.716
ZNF746 zinc finger protein 746 0.702
SPRY4 sprouty homolog 4 (Drosophila) 0.699
BCAR1 breast cancer anti-estrogen resistance 1 0.697
PDLIM7 PDZ and LIM domain 7 (enigma) 0.682
CAV1 caveolin 1, caveolae protein, 22kDa 0.679
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.671
EPS8 epidermal growth factor receptor pathway substrate 8 0.663
ILK integrin-linked kinase 0.627
FLNB filamin B, beta 0.625
YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.615
ACTN1 actinin, alpha 1 0.615
DAAM1 dishevelled associated activator of morphogenesis 1 0.613
PDCD6IP programmed cell death 6 interacting protein 0.607
S100A9 S100 calcium binding protein A9 0.606
CAPZB capping protein (actin filament) muscle Z-line, beta 0.594
ESR1 estrogen receptor 1 0.583
CTGF connective tissue growth factor 0.572
RHOC ras homolog gene family, member C 0.571
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.547
S100A8 S100 calcium binding protein A8 0.546
TRIP10 thyroid hormone receptor interactor 10 0.537
ARHGAP1 Rho GTPase activating protein 1 0.535
SORBS3 sorbin and SH3 domain containing 3 0.527
CTTN cortactin 0.525
EPHA2 EPH receptor A2 0.516
PTK2B PTK2B protein tyrosine kinase 2 beta 0.509
TNK2 tyrosine kinase, non-receptor, 2 0.505
NCKAP1 NCK-associated protein 1 0.491
TPM1 tropomyosin 1 (alpha) 0.481
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.471
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.465
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.460
ANXA2 annexin A2 0.458
NCL nucleolin 0.458
ARRB2 arrestin, beta 2 0.447
WASF1 WAS protein family, member 1 0.447
UBC ubiquitin C 0.444
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.443
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Efnb2 ephrin B2 0.999
Rac1 RAS-related C3 botulinum substrate 1 0.997
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.997
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.988
Vasp vasodilator-stimulated phosphoprotein 0.982
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.982
Cbl Casitas B-lineage lymphoma 0.976
Ephb2 Eph receptor B2 0.974
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.972
Apc adenomatosis polyposis coli 0.971
Pick1 protein interacting with C kinase 1 0.941
Grb2 growth factor receptor bound protein 2 0.938
Dab1 disabled homolog 1 (Drosophila) 0.937
Cttn cortactin 0.935
Plcg1 phospholipase C, gamma 1 0.927
Capzb capping protein (actin filament) muscle Z-line, beta 0.927
Ldb3 LIM domain binding 3 0.921
Wdr1 WD repeat domain 1 0.913
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.908
Lrrk2 leucine-rich repeat kinase 2 0.905
Abi1 abl-interactor 1 0.858
Epha4 Eph receptor A4 0.837
Actb actin, beta 0.830
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.829
Prkce protein kinase C, epsilon 0.819
Ephb3 Eph receptor B3 0.805
Arpc4 actin related protein 2/3 complex, subunit 4 0.801
Wipf1 WAS/WASL interacting protein family, member 1 0.798
Akt1 thymoma viral proto-oncogene 1 0.769
Enah enabled homolog (Drosophila) 0.752
Lama5 laminin, alpha 5 0.736
Bcl2 B-cell leukemia/lymphoma 2 0.731
Gsk3b glycogen synthase kinase 3 beta 0.729
Ptk2 PTK2 protein tyrosine kinase 2 0.718
Csf1 colony stimulating factor 1 (macrophage) 0.713
Hif1a hypoxia inducible factor 1, alpha subunit 0.709
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.708
Axin1 axin 1 0.684
Vcl vinculin 0.666
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.652
Cltc clathrin, heavy polypeptide (Hc) 0.648
Msn moesin 0.644
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.629
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.595
Apaf1 apoptotic peptidase activating factor 1 0.594
Nf2 neurofibromatosis 2 0.594
Src Rous sarcoma oncogene 0.589
Mpdz multiple PDZ domain protein 0.587
Pten phosphatase and tensin homolog 0.565
Vangl2 vang-like 2 (van gogh, Drosophila) 0.565
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.558
Plcg2 phospholipase C, gamma 2 0.548
Actg1 actin, gamma, cytoplasmic 1 0.541
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.539
Dok1 docking protein 1 0.532
Ptk7 PTK7 protein tyrosine kinase 7 0.520
Rod1 ROD1 regulator of differentiation 1 (S. pombe) 0.510
Tbx2 T-box 2 0.509
Mtpn myotrophin 0.503
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.503
Fzd2 frizzled homolog 2 (Drosophila) 0.494
Vangl1 vang-like 1 (van gogh, Drosophila) 0.490
Irs1 insulin receptor substrate 1 0.483
Capn1 calpain 1 0.481
Bcam basal cell adhesion molecule 0.477
Ptch1 patched homolog 1 0.475
Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 0.473
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.471
Pecam1 platelet/endothelial cell adhesion molecule 1 0.446
Arhgap1 Rho GTPase activating protein 1 0.440
Csrp1 cysteine and glycine-rich protein 1 0.439
Cit citron 0.434
Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.415
Actn2 actinin alpha 2 0.412
Myo1c myosin IC 0.408
Pxn paxillin 0.406
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.401
Mapkap1 mitogen-activated protein kinase associated protein 1 0.399
Gnb1 guanine nucleotide binding protein (G protein), beta 1 0.398
Pfn2 profilin 2 0.392
Ptprc protein tyrosine phosphatase, receptor type, C 0.388
Itga3 integrin alpha 3 0.368
Kalrn kalirin, RhoGEF kinase 0.363
Nfe2l3 nuclear factor, erythroid derived 2, like 3 0.362
Iqgap1 IQ motif containing GTPase activating protein 1 0.361
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.361
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.360
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.355
Gab1 growth factor receptor bound protein 2-associated protein 1 0.352
Tmod3 tropomodulin 3 0.346
Nf1 neurofibromatosis 1 0.341
Braf Braf transforming gene 0.339
Ptprg protein tyrosine phosphatase, receptor type, G 0.337
Fzd1 frizzled homolog 1 (Drosophila) 0.337
Jup junction plakoglobin 0.336
Was Wiskott-Aldrich syndrome homolog (human) 0.333
Arpc2 actin related protein 2/3 complex, subunit 2 0.324
Acta2 actin, alpha 2, smooth muscle, aorta 0.318
Il6st interleukin 6 signal transducer 0.318
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tagln transgelin 0.575
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.571
Efhd2 EF-hand domain family, member D2 0.486
Pfn1 profilin 1 0.430
Arpc2 actin related protein 2/3 complex, subunit 2 0.325
Tpm3 tropomyosin 3, gamma 0.295
Arf6 ADP-ribosylation factor 6 0.244
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.183
Rap1b RAP1B, member of RAS oncogene family 0.173
Acta2 smooth muscle alpha-actin 0.170
Rab1b RAB1B, member RAS oncogene family 0.155
Sirpa signal-regulatory protein alpha 0.131
Ptbp1 polypyrimidine tract binding protein 1 0.120
Myh9 myosin, heavy chain 9, non-muscle 0.120
Fgfr1 Fibroblast growth factor receptor 1 0.100
Cdc42 cell division cycle 42 (GTP binding protein) 0.095
Arpc1b actin related protein 2/3 complex, subunit 1B 0.094
Arpc5 actin related protein 2/3 complex, subunit 5 0.088
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.084
Cttn cortactin 0.082
Anxa2 annexin A2 0.079
Lmna lamin A 0.071
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.070
Dstn destrin 0.068
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.067
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.061
Fkbp1a FK506 binding protein 1a 0.059
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.058
Cd37 CD37 molecule 0.058
Cd38 CD38 molecule 0.058
Cast calpastatin 0.054
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.053
Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 0.052
Shank2 SH3 and multiple ankyrin repeat domains 2 0.048
Coro1a coronin, actin binding protein 1A 0.047
Tmpo thymopoietin 0.047
Prkcd protein kinase C, delta 0.046
Actb actin, beta 0.045
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.045
Stk17b serine/threonine kinase 17b 0.044
Taok1 TAO kinase 1 0.044
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.043
Csnk1g3 casein kinase 1, gamma 3 0.042
Dlg3 discs, large homolog 3 (Drosophila) 0.042
Wdr1 WD repeat domain 1 0.042
Sri sorcin 0.039
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.038
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.037
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.037
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.036
Eif4h eukaryotic translation initiation factor 4H 0.036
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.036
Arpc3 actin related protein 2/3 complex, subunit 3 0.035
Grm8 glutamate receptor, metabotropic 8 0.035
Clic1 chloride intracellular channel 1 0.034
Ppyr1 pancreatic polypeptide receptor 1 0.034
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.034
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.034
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.034
Msn moesin 0.034
Fgf7 fibroblast growth factor 7 0.034
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.033
Col12a1 collagen, type XII, alpha 1 0.033
Jak2 Janus kinase 2 0.032
Tubb5 tubulin, beta 5 0.032
Ubtf upstream binding transcription factor, RNA polymerase I 0.032
Ptprd protein tyrosine phosphatase, receptor type, D 0.032
Abi1 abl-interactor 1 0.032
Efnb1 ephrin B1 0.031
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.031
Lcp1 lymphocyte cytosolic protein 1 0.031
Dgkg diacylglycerol kinase, gamma 0.030
Sat1 spermidine/spermine N1-acetyl transferase 1 0.030
Itgb1 integrin, beta 1 0.030
Pgf placental growth factor 0.030
Hk1 hexokinase 1 0.029
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.029
Cd82 Cd82 molecule 0.028
Arl5a ADP-ribosylation factor-like 5A 0.028
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.028
Prelid1 PRELI domain containing 1 0.027
Smad3 SMAD family member 3 0.027
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.027
Nfya nuclear transcription factor-Y alpha 0.027
Ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.026
Capn9 calpain 9 0.026
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.026
Smap2 small ArfGAP2 0.026
Rhoa ras homolog gene family, member A 0.026
Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 0.026
Lcp2 lymphocyte cytosolic protein 2 0.026
Myo1c myosin IC 0.026
Lasp1 LIM and SH3 protein 1 0.025
Capzb capping protein (actin filament) muscle Z-line, beta 0.025
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.025
Usf1 upstream transcription factor 1 0.025
Marcks myristoylated alanine rich protein kinase C substrate 0.025
Iqgap1 IQ motif containing GTPase activating protein 1 0.025
Cfl1 cofilin 1, non-muscle 0.025
Dbnl drebrin-like 0.024