The network for 'rna modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rna modification

The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.

Name Description Probability Func Analog Organism
ELP3 Elp3p 1.000
YNL022C hypothetical protein 1.000
IKI3 Iki3p 0.999
DEG1 Deg1p 0.999
PUS7 Pus7p 0.999
NCS2 Ncs2p 0.999
IME4 Ime4p 0.999
CBF5 Cbf5p 0.997
IKI1 Iki1p 0.997
NCS6 Ncs6p 0.997
ELP6 Elp6p 0.996
ELP4 Elp4p 0.995
URM1 Urm1p 0.995
KTI12 Kti12p 0.994
MUM2 Mum2p 0.992
PUS4 Pus4p 0.991
ELP2 Elp2p 0.986
RRP6 Rrp6p 0.983
KTI11 Kti11p 0.980
TRM1 Trm1p 0.973
PUS1 Pus1p 0.961
PCC1 Pcc1p 0.952
TRM11 Trm11p 0.948
NRD1 Nrd1p 0.922
MTO1 Mto1p 0.918
TRM9 Trm9p 0.906
UBA4 Uba4p 0.881
NAB3 Nab3p 0.849
SUA5 Sua5p 0.838
NHP2 Nhp2p 0.818
TGS1 Tgs1p 0.816
TRM8 Trm8p 0.782
DPH2 Dph2p 0.776
MEX67 Mex67p 0.760
YHR003C hypothetical protein 0.756
SMM1 Smm1p 0.737
SLM3 Slm3p 0.693
TRM12 Trm12p 0.673
TRM10 Trm10p 0.634
YCR051W hypothetical protein 0.633
YIL096C hypothetical protein 0.627
MSS1 Mss1p 0.609
ABP140 Abp140p 0.604
MER1 Mer1p 0.595
TAD2 Tad2p 0.541
RRP8 Rrp8p 0.529
YBL081W hypothetical protein 0.508
TRM13 Trm13p 0.495
RRP12 Rrp12p 0.485
CEG1 Ceg1p 0.450
DUS1 Dus1p 0.440
TAF8 Taf8p 0.438
TUM1 Tum1p 0.430
TRM112 Trm112p 0.429
TPA1 Tpa1p 0.421
SWM2 Swm2p 0.407
YML082W hypothetical protein 0.400
PUS6 Pus6p 0.395
YGR210C hypothetical protein 0.391
RIM2 Rim2p 0.388
RTT10 Rtt10p 0.375
YPL245W hypothetical protein 0.368
TSR1 Tsr1p 0.361
LOS1 Los1p 0.353
TRM5 Trm5p 0.350
HRR25 Hrr25p 0.340
DUS4 Dus4p 0.340
RNH70 Rnh70p 0.339
ERC1 Erc1p 0.331
DUS3 Dus3p 0.327
YGR012W hypothetical protein 0.325
YNL035C hypothetical protein 0.322
POC4 Poc4p 0.321
NFS1 Nfs1p 0.317
TRM82 Trm82p 0.297
YBR242W hypothetical protein 0.294
RPA34 Rpa34p 0.286
TRM2 Trm2p 0.280
DFR1 Dfr1p 0.280
YMR259C hypothetical protein 0.279
YKL027W hypothetical protein 0.273
TAD3 Tad3p 0.272
NMD5 Nmd5p 0.272
YMR310C hypothetical protein 0.268
GFD2 Gfd2p 0.267
PNO1 Pno1p 0.266
TRS31 Trs31p 0.263
KAE1 Kae1p 0.260
RIT1 Rit1p 0.249
RRB1 Rrb1p 0.246
LEU9 Leu9p 0.235
CCM1 Ccm1p 0.235
YJR003C hypothetical protein 0.225
GBP2 Gbp2p 0.224
MOD5 Mod5p 0.222
YBR271W hypothetical protein 0.222
BER1 Ber1p 0.221
POP8 Pop8p 0.220
PUS2 Pus2p 0.219
NBP35 Nbp35p 0.219
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pdlim3b PDZ and LIM domain 3b 0.625
pdlim7 PDZ and LIM domain 7 0.385
csnk1db casein kinase 1, delta b 0.363
qtrt1 queuine tRNA-ribosyltransferase 1 0.233
csnk1da casein kinase 1, delta a 0.226
kidins220b kinase D-interacting substrate of 220b 0.212
fancl Fanconi anemia, complementation group L 0.210
zgc:113210 zgc:113210 0.210
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.205
mapk14a mitogen-activated protein kinase 14a 0.167
golt1b golgi transport 1 homolog B (S. cerevisiae) 0.159
eif3b eukaryotic translation initiation factor 3, subunit B 0.144
aldocb aldolase C, fructose-bisphosphate, b 0.142
nedd1 neural precursor cell expressed, developmentally down-regulated 1 0.127
prmt3 protein arginine methyltransferase 3 0.121
nop58 NOP58 ribonucleoprotein homolog (yeast) 0.113
zgc:101768 zgc:101768 0.101
ndrg4 N-myc downstream regulated gene 4 0.101
im:7163520 im:7163520 0.096
si:dkey-177p2.6 si:dkey-177p2.6 0.092
prmt7 protein arginine N-methyltransferase 7 0.090
extl3 exostoses (multiple)-like 3 0.086
prmt5 protein arginine methyltransferase 5 0.081
nol10 nucleolar protein 10 0.080
ldhd lactate dehydrogenase D 0.080
limk2 LIM domain kinase 2 0.078
znrd1 zinc ribbon domain containing 1 0.076
rcc1 regulator of chromosome condensation 1 0.074
qtrtd1 queuine tRNA-ribosyltransferase domain containing 1 0.073
mettl2a methyltransferase like 2A 0.067
zgc:56457 zgc:56457 0.065
si:ch211-198a12.6 si:ch211-198a12.6 0.064
vmp1 vacuole membrane protein 1 0.064
unc45a unc-45 homolog A (C. elegans) 0.061
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.061
ppp3ca protein phosphatase 3, catalytic subunit, alpha isozyme 0.059
phf23b PHD finger protein 23b 0.058
dag1 dystroglycan 1 0.058
si:ch211-196f5.1 si:ch211-196f5.1 0.056
mef2cb myocyte enhancer factor 2cb 0.056
chuk conserved helix-loop-helix ubiquitous kinase 0.056
max myc-associated factor X 0.055
glb1 galactosidase, beta 1 0.055
slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 0.053
gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.053
rrp9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 0.053
tyw3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) 0.052
barx1 BarH-like homeobox 1 0.052
rpl7l1 ribosomal protein L7-like 1 0.051
ip6k2 inositol hexaphosphate kinase 2 0.049
LOC555692 G patch domain containing 4-like 0.048
mtmr12 myotubularin related protein 12 0.048
utp6 UTP6, small subunit (SSU) processome component, homolog (yeast) 0.047
mtm1 myotubularin 1 0.046
wdr12 WD repeat domain 12 0.046
tars threonyl-tRNA synthetase 0.046
rpp38 ribonuclease P/MRP 38 subunit 0.045
mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.042
smyhc2 slow myosin heavy chain 2 0.042
klf2b Kruppel-like factor 2b 0.042
mycl1b v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b 0.041
alg3 asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) 0.041
wnt7aa wingless-type MMTV integration site family, member 7Aa 0.040
lhx6 LIM homeobox 6 0.040
pdlim4 PDZ and LIM domain 4 0.040
gtf2h2 general transcription factor IIH, polypeptide 2 0.040
csnk1e casein kinase 1, epsilon 0.039
slc30a4 solute carrier family 30 (zinc transporter), member 4 0.038
lrrc4.1 leucine rich repeat containing 4.1 0.038
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.037
srm spermidine synthase 0.037
gtf3aa general transcription factor IIIAa 0.037
kop askopos 0.036
arih1l ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like 0.036
ruvbl2 RuvB-like 2 (E. coli) 0.035
dpysl3 dihydropyrimidinase-like 3 0.035
nup155 nucleoporin 155 0.035
nsun2 NOL1/NOP2/Sun domain family, member 2 0.034
aatf apoptosis antagonizing transcription factor 0.033
si:ch211-114c12.2 si:ch211-114c12.2 0.033
usp7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.033
rhov ras homolog gene family, member V 0.033
nolc1 nucleolar and coiled-body phosphoprotein 1 0.032
smfn small fragment nuclease 0.032
pdlim2 PDZ and LIM domain 2 (mystique) 0.032
mocs3 molybdenum cofactor synthesis 3 0.032
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.031
dkc1 dyskeratosis congenita 1, dyskerin 0.031
htra1a HtrA serine peptidase 1a 0.031
LOC100334210 growth/differentiation factor 5-like 0.030
slc30a6 solute carrier family 30 (zinc transporter), member 6 0.030
srrt serrate RNA effector molecule homolog (Arabidopsis) 0.030
si:dkey-273o13.1 si:dkey-273o13.1 0.030
mych myelocytomatosis oncogene homolog 0.030
rorab RAR-related orphan receptor A, paralog b 0.029
kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.029
wdr36 WD repeat domain 36 0.029
sh3gl2 SH3-domain GRB2-like 2 0.029
snupn snurportin 1 0.029
foxp1b forkhead box P1b 0.029
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.977
ELP3 elongation protein 3 homolog (S. cerevisiae) 0.972
ELP4 elongation protein 4 homolog (S. cerevisiae) 0.766
METTL1 methyltransferase like 1 0.674
ELP2 elongation protein 2 homolog (S. cerevisiae) 0.652
NOP56 NOP56 ribonucleoprotein homolog (yeast) 0.481
WDR4 WD repeat domain 4 0.447
NOP58 NOP58 ribonucleoprotein homolog (yeast) 0.372
SMN1 survival of motor neuron 1, telomeric 0.113
TP53RK TP53 regulating kinase 0.099
NAT10 N-acetyltransferase 10 (GCN5-related) 0.079
DDX24 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 0.076
FBL fibrillarin 0.070
EIF3G eukaryotic translation initiation factor 3, subunit G 0.068
NAF1 nuclear assembly factor 1 homolog (S. cerevisiae) 0.062
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 0.062
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.058
RUVBL1 RuvB-like 1 (E. coli) 0.055
SP110 SP110 nuclear body protein 0.052
MKI67IP MKI67 (FHA domain) interacting nucleolar phosphoprotein 0.049
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.047
NIP7 nuclear import 7 homolog (S. cerevisiae) 0.046
GAR1 GAR1 ribonucleoprotein homolog (yeast) 0.043
MYST2 MYST histone acetyltransferase 2 0.041
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.040
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.038
NVL nuclear VCP-like 0.037
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.035
COIL coilin 0.034
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 0.033
XRN2 5'-3' exoribonuclease 2 0.033
DDX56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.031
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 0.030
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.029
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.029
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.027
FAM96B family with sequence similarity 96, member B 0.026
PRMT1 protein arginine methyltransferase 1 0.025
LAGE3 L antigen family, member 3 0.025
NOP14 NOP14 nucleolar protein homolog (yeast) 0.025
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 0.025
EIF3D eukaryotic translation initiation factor 3, subunit D 0.025
WDYHV1 WDYHV motif containing 1 0.024
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.024
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.023
PUS1 pseudouridylate synthase 1 0.023
SDAD1 SDA1 domain containing 1 0.022
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.022
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.022
ANKRD28 ankyrin repeat domain 28 0.022
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.022
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 0.021
POLR1C polymerase (RNA) I polypeptide C, 30kDa 0.021
SLC25A38 solute carrier family 25, member 38 0.020
RSL1D1 ribosomal L1 domain containing 1 0.020
RCL1 RNA terminal phosphate cyclase-like 1 0.020
C19orf60 chromosome 19 open reading frame 60 0.020
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.020
LTV1 LTV1 homolog (S. cerevisiae) 0.020
DPH2 DPH2 homolog (S. cerevisiae) 0.020
ASCC2 activating signal cointegrator 1 complex subunit 2 0.020
GPN1 GPN-loop GTPase 1 0.020
NCL nucleolin 0.019
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.019
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.018
DIEXF digestive organ expansion factor homolog (zebrafish) 0.018
WDR74 WD repeat domain 74 0.018
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.018
CCDC86 coiled-coil domain containing 86 0.018
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 0.018
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.018
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 0.017
YDJC YdjC homolog (bacterial) 0.017
CRELD2 cysteine-rich with EGF-like domains 2 0.017
PWP1 PWP1 homolog (S. cerevisiae) 0.017
XPO5 exportin 5 0.017
PRMT6 protein arginine methyltransferase 6 0.017
LIAS lipoic acid synthetase 0.017
NUBP2 nucleotide binding protein 2 (MinD homolog, E. coli) 0.017
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 0.016
C7orf64 chromosome 7 open reading frame 64 0.016
CSNK1E casein kinase 1, epsilon 0.016
WDR73 WD repeat domain 73 0.016
FASTKD2 FAST kinase domains 2 0.016
DCTPP1 dCTP pyrophosphatase 1 0.016
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.016
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.015
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.015
ZNF775 zinc finger protein 775 0.015
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) 0.015
LARS leucyl-tRNA synthetase 0.015
METTL17 methyltransferase like 17 0.015
NXT1 NTF2-like export factor 1 0.014
MAK16 MAK16 homolog (S. cerevisiae) 0.014
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 0.014
NOP2 NOP2 nucleolar protein homolog (yeast) 0.014
OSTF1 osteoclast stimulating factor 1 0.014
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.014
FTSJD2 FtsJ methyltransferase domain containing 2 0.014
LENG1 leukocyte receptor cluster (LRC) member 1 0.014
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Mus musculus
Name Description Probability Func Analog Organism
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.041
Mrps18b mitochondrial ribosomal protein S18B 0.039
Hdac2 histone deacetylase 2 0.030
Smyd5 SET and MYND domain containing 5 0.024
Per2 period homolog 2 (Drosophila) 0.021
Srm spermidine synthase 0.019
Pdia6 protein disulfide isomerase associated 6 0.019
Gars glycyl-tRNA synthetase 0.017
Lrrc59 leucine rich repeat containing 59 0.016
Ftsj3 FtsJ homolog 3 (E. coli) 0.015
Hnrnpd heterogeneous nuclear ribonucleoprotein D 0.015
Vars valyl-tRNA synthetase 0.014
Hnrpdl heterogeneous nuclear ribonucleoprotein D-like 0.013
Gmppb GDP-mannose pyrophosphorylase B 0.013
Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 0.013
Ddx41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 0.012
Yars tyrosyl-tRNA synthetase 0.012
Ccdc86 coiled-coil domain containing 86 0.012
Sox4 SRY-box containing gene 4 0.011
Wdr46 WD repeat domain 46 0.011
Ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.011
Parn poly(A)-specific ribonuclease (deadenylation nuclease) 0.011
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.011
Utp20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.010
Bop1 block of proliferation 1 0.010
Alg3 asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase) 0.010
Creld2 cysteine-rich with EGF-like domains 2 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism