The network for 'positive regulation of nucleotide catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of nucleotide catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.

Name Description Probability Func Analog Organism
GCD6 Gcd6p 0.542
MKK1 Mkk1p 0.276
STE11 Ste11p 0.260
SUI3 Sui3p 0.226
RHO1 Rho1p 0.211
CDC24 Cdc24p 0.180
STI1 Sti1p 0.154
SUI2 Sui2p 0.153
STE5 Ste5p 0.143
SSA4 Ssa4p 0.137
GDI1 Gdi1p 0.087
IRA1 Ira1p 0.082
KEL1 Kel1p 0.081
VPS15 Vps15p 0.074
SPA2 Spa2p 0.071
ROM2 Rom2p 0.070
MDS3 Mds3p 0.069
RGA2 Rga2p 0.066
SAC7 Sac7p 0.065
TOM1 Tom1p 0.064
NET1 Net1p 0.059
CYK3 Cyk3p 0.059
FYV8 Fyv8p 0.058
FKH1 Fkh1p 0.054
ATG20 Atg20p 0.054
MSG5 Msg5p 0.052
CHS1 Chs1p 0.052
SKT5 Skt5p 0.051
PKC1 Pkc1p 0.050
SOG2 Sog2p 0.049
YIP3 Yip3p 0.049
FIR1 Fir1p 0.048
VPS4 Vps4p 0.047
ACK1 Ack1p 0.047
PTP2 Ptp2p 0.047
PEA2 Pea2p 0.047
BEM3 Bem3p 0.047
INP53 Inp53p 0.046
GPB2 Gpb2p 0.046
PRS2 Prs2p 0.045
AKL1 Akl1p 0.045
YPT53 Ypt53p 0.044
SEC16 Sec16p 0.043
RPN14 Rpn14p 0.041
RRI1 Rri1p 0.040
BEM4 Bem4p 0.038
MOB2 Mob2p 0.037
HSP78 Hsp78p 0.037
YIL055C hypothetical protein 0.035
FAR1 Far1p 0.035
DOP1 Dop1p 0.035
RGD1 Rgd1p 0.035
GCD1 Gcd1p 0.034
EXO84 Exo84p 0.034
TOF2 Tof2p 0.033
FAA2 Faa2p 0.033
YRB1 Yrb1p 0.033
PKH2 Pkh2p 0.033
INO2 Ino2p 0.033
TUS1 Tus1p 0.032
BST1 Bst1p 0.032
STT4 Stt4p 0.031
VTA1 Vta1p 0.031
GID7 Gid7p 0.031
SSK1 Ssk1p 0.030
MNN9 Mnn9p 0.030
YDR348C hypothetical protein 0.030
PPE1 Ppe1p 0.030
SWC7 Swc7p 0.029
CDC25 Cdc25p 0.029
YDL206W hypothetical protein 0.029
YML002W hypothetical protein 0.029
BRN1 Brn1p 0.029
BPT1 Bpt1p 0.029
STE20 Ste20p 0.029
ARP10 Arp10p 0.028
GCD7 Gcd7p 0.028
HSV2 Hsv2p 0.028
AST2 Ast2p 0.028
NEO1 Neo1p 0.027
YNL108C hypothetical protein 0.027
SVF1 Svf1p 0.027
NOP10 Nop10p 0.027
SET1 Set1p 0.027
PKH1 Pkh1p 0.027
TAM41 Tam41p 0.027
URA3 Ura3p 0.026
STE2 Ste2p 0.026
SSK2 Ssk2p 0.026
TRS65 Trs65p 0.026
CDC50 Cdc50p 0.025
MKK2 Mkk2p 0.025
YLR264C-A hypothetical protein 0.025
BEM2 Bem2p 0.025
CMK2 Cmk2p 0.025
BRO1 Bro1p 0.025
YPR174C hypothetical protein 0.025
SPR6 Spr6p 0.025
NUP85 Nup85p 0.025
SAN1 San1p 0.025
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.224
goa-1 Protein GOA-1 0.218
flh-2 Protein FLH-2 0.196
CELE_F47G4.4 Protein F47G4.4 0.156
lag-1 Protein LAG-1 0.142
zfp-3 Protein ZFP-3 0.135
F09C8.2 Protein F09C8.2 0.111
C11H1.3 Protein C11H1.3 0.103
rig-6 Protein RIG-6 0.103
unc-53 Protein UNC-53 0.090
let-60 Protein LET-60 0.085
mpk-1 Protein MPK-1 0.084
sad-1 Protein SAD-1 0.077
C06A5.8 Protein C06A5.8 0.072
gex-2 Protein GEX-2 0.071
eor-2 Protein EOR-2 0.069
R11A8.7 Protein R11A8.7 0.065
egl-8 Protein EGL-8 0.065
T28B11.1 Protein T28B11.1 0.065
fhod-1 Protein FHOD-1 0.064
CELE_F25B4.5 Protein F25B4.5 0.063
afd-1 Protein AFD-1 0.062
egrh-1 Protein EGRH-1 0.062
rfc-1 Protein RFC-1 0.061
plc-3 Protein PLC-3 0.061
C15H9.5 Protein C15H9.5 0.061
rme-4 Protein RME-4 0.059
sax-3 Protein SAX-3 0.059
F52G3.1 Protein F52G3.1 0.058
cyld-1 Protein CYLD-1 0.057
abts-1 Protein ABTS-1 0.057
uso-1 Protein USO-1 0.056
abl-1 Protein ABL-1 0.055
magi-1 Protein MAGI-1 0.055
snf-1 Protein SNF-1 0.055
C11E4.6 Protein C11E4.6 0.051
R90.1 Protein R90.1 0.050
eor-1 Protein EOR-1 0.050
nrx-1 Protein NRX-1 0.049
stau-1 Protein STAU-1 0.048
gpr-2 Protein GPR-2 0.046
zoo-1 Protein ZOO-1 0.045
ptp-4 Protein PTP-4 0.045
W07E11.1 Protein W07E11.1 0.044
CELE_T26A8.4 Protein T26A8.4 0.043
ttx-1 Protein TTX-1 0.043
sam-10 Protein SAM-10 0.042
T23F2.2 Protein T23F2.2 0.042
F13B9.1 Protein F13B9.1 0.042
sma-9 Protein SMA-9 0.041
mrck-1 Protein MRCK-1 0.040
CELE_Y69A2AR.28 Protein Y69A2AR.28 0.039
Y48C3A.14 Protein Y48C3A.14 0.038
rpm-1 Protein RPM-1 0.038
mbk-1 Protein MBK-1 0.038
pqn-39 Protein PQN-39 0.038
smc-6 Protein SMC-6 0.038
fnta-1 Protein FNTA-1 0.038
dpy-21 Protein DPY-21 0.038
sel-8 Protein SEL-8 0.038
pkg-1 Protein PKG-1 0.037
zyg-9 Protein ZYG-9 0.037
ntl-4 Protein NTL-4 0.037
dpy-27 Protein DPY-27 0.035
chc-1 Protein CHC-1 0.035
pat-12 Protein PAT-12 0.035
sav-1 Protein SAV-1 0.034
ajm-1 Protein AJM-1 0.034
acr-2 Protein ACR-2 0.034
gar-3 Protein GAR-3 0.033
T23F11.1 Protein T23F11.1 0.033
unc-26 Protein UNC-26 0.033
let-805 Protein LET-805 0.033
F13H6.1 Protein F13H6.1 0.033
pkn-1 Protein PKN-1 0.032
rsbp-1 Protein RSBP-1 0.032
bet-2 Protein BET-2 0.032
sup-17 Protein SUP-17 0.032
F28B3.1 Protein F28B3.1 0.031
aha-1 Protein AHA-1 0.031
frm-7 Protein FRM-7 0.031
ptp-1 Protein PTP-1 0.031
mpz-1 Protein MPZ-1 0.031
mei-1 Protein MEI-1 0.031
CELE_Y60A3A.9 Protein Y60A3A.9 0.030
unc-79 Protein UNC-79 0.030
pry-1 Protein PRY-1 0.030
F10D7.5 Protein F10D7.5 0.030
itr-1 Protein ITR-1 0.030
sorb-1 Protein SORB-1 0.030
unc-80 Protein UNC-80 0.029
egg-6 Protein EGG-6 0.029
tag-343 Protein TAG-343 0.028
lron-15 Protein LRON-15 0.028
T14B1.1 Protein T14B1.1 0.028
unc-31 Protein UNC-31 0.027
ced-6 Protein CED-6 0.027
gpb-1 Protein GPB-1 0.027
glb-6 Protein GLB-6 0.027
egl-36 Protein EGL-36 0.027
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
hsp90a.2 heat shock protein 90-alpha 2 0.234
bida BH3 interacting domain death agonist 0.181
bcl2 B-cell leukemia/lymphoma 2 0.175
hspa4a heat shock protein 4a 0.160
rtcd1 RNA terminal phosphate cyclase domain 1 0.140
tpm4 tropomyosin 4 0.137
actc1a actin, alpha, cardiac muscle 1a 0.124
msna moesin a 0.120
si:ch211-232m7.1 si:ch211-232m7.1 0.119
nf1a neurofibromin 1a 0.087
mcl1b myeloid cell leukemia sequence 1b 0.087
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.081
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.079
adrb2a adrenergic receptor, beta 2a 0.078
efna1b ephrin A1b 0.077
dedd1 death effector domain-containing 1 0.075
dnaja1l DnaJ (Hsp40) homolog, subfamily A, member 1, like 0.072
mat2a methionine adenosyltransferase II, alpha 0.071
zgc:55259 zgc:55259 0.069
baxa bcl2-associated X protein, a 0.068
sox4a SRY-box containing gene 4a 0.067
acvr1b activin A receptor, type IB 0.067
ampd3 adenosine monophosphate deaminase 3 0.066
dzip1 DAZ interacting protein 1 0.065
acsl4a acyl-CoA synthetase long-chain family member 4a 0.065
slc12a9 solute carrier family 12 (potassium/chloride transporters), member 9 0.065
scinlb scinderin like b 0.062
nf1b neurofibromin 1b 0.061
im:7137453 im:7137453 0.061
znf259 zinc finger protein 259 0.059
tomm34 translocase of outer mitochondrial membrane 34 0.059
anxa1a annexin A1a 0.059
sox2 SRY-box containing gene 2 0.058
icn ictacalcin 0.057
gclc glutamate-cysteine ligase, catalytic subunit 0.056
prom1a prominin 1a 0.054
dnmt7 DNA (cytosine-5-)-methyltransferase 7 0.053
lonp1 lon peptidase 1, mitochondrial 0.053
sox7 SRY-box containing gene 7 0.052
boka BCL2-related ovarian killer a 0.050
rtn1a reticulon 1a 0.049
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.049
tsc22d3 TSC22 domain family, member 3 0.049
zgc:77517 zgc:77517 0.049
march6 membrane-associated ring finger (C3HC4) 6 0.049
cldnk claudin k 0.048
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.048
gpc4 glypican 4 0.048
yrk Yes-related kinase 0.048
dnajb1b DnaJ (Hsp40) homolog, subfamily B, member 1b 0.048
krt18 keratin 18 0.048
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.047
cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.047
wu:fi25h02 wu:fi25h02 0.047
depdc1a DEP domain containing 1a 0.046
mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.046
gsna gelsolin a 0.045
ahctf1 AT hook containing transcription factor 1 0.044
zgc:113028 zgc:113028 0.044
gstal glutathione S-transferase, alpha-like 0.043
rcn1 reticulocalbin 1, EF-hand calcium binding domain 0.042
ptgs2a prostaglandin-endoperoxide synthase 2a 0.042
fem1c fem-1 homolog c (C.elegans) 0.042
iqgap1 IQ motif containing GTPase activating protein 1 0.042
ptprk protein tyrosine phosphatase, receptor type, K 0.042
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.042
nme2b.2 non-metastatic cells 2b.2, protein (NM23B) expressed in 0.041
zgc:77752 zgc:77752 0.041
rhoaa ras homolog gene family, member Aa 0.041
tm9sf2 transmembrane 9 superfamily member 2 0.041
capns1b calpain, small subunit 1 b 0.041
brap BRCA1 associated protein 0.041
dnmt5 DNA (cytosine-5-)-methyltransferase 5 0.040
nrarpa notch-regulated ankyrin repeat protein a 0.040
epb4.1l4 erythrocyte protein band 4.1-like 4 0.040
kif20bb kinesin family member 20Bb 0.040
zgc:112018 zgc:112018 0.040
pvalb2 parvalbumin 2 0.040
zgc:100838 zgc:100838 0.040
ncapg non-SMC condensin I complex, subunit G 0.040
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.040
ube2d1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.040
pdlim1 PDZ and LIM domain 1 (elfin) 0.039
chac1 ChaC, cation transport regulator-like 1 0.039
pvalb4 parvalbumin 4 0.039
sox21a SRY-box containing gene 21a 0.039
cnn2 calponin 2 0.039
wu:fb39a06 wu:fb39a06 0.038
ldb3a LIM-domain binding factor 3a 0.038
optc opticin 0.038
ccna2 cyclin A2 0.038
rras related RAS viral (r-ras) oncogene homolog 0.038
ncs1a neuronal calcium sensor 1a 0.038
nus1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 0.038
uba1 ubiquitin-like modifier activating enzyme 1 0.038
mycbp2 MYC binding protein 2 0.037
rbm19 RNA binding motif protein 19 0.037
ssbp4 single stranded DNA binding protein 4 0.037
dnajb1a DnaJ (Hsp40) homolog, subfamily B, member 1a 0.037
lifrb leukemia inhibitory factor receptor alpha b 0.037
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pkn Protein kinase related to protein kinase N 0.487
puc puckered 0.482
Sos Son of sevenless 0.447
pod1 CG4532 gene product from transcript CG4532-RF 0.430
Rheb CG1081 gene product from transcript CG1081-RA 0.345
cno canoe 0.298
neuroligin CG13772 gene product from transcript CG13772-RA 0.287
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.260
plexB plexin B 0.254
rok Rho-kinase 0.233
Stat92E Signal-transducer and activator of transcription protein at 92E 0.217
stg string 0.202
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.199
Wnk CG7177 gene product from transcript CG7177-RA 0.194
stai stathmin 0.170
mav maverick 0.168
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.162
mask multiple ankyrin repeats single KH domain 0.152
egl egalitarian 0.147
Mtl Mig-2-like 0.142
Pten CG5671 gene product from transcript CG5671-RB 0.128
unc-104 CG8566 gene product from transcript CG8566-RB 0.117
nwk nervous wreck 0.113
tmod tropomodulin 0.113
Smg1 CG32743 gene product from transcript CG32743-RA 0.110
dos daughter of sevenless 0.109
drpr draper 0.108
neur neuralized 0.106
synj synaptojanin 0.104
Su(H) Suppressor of Hairless 0.100
raps rapsynoid 0.100
CG8155 CG8155 gene product from transcript CG8155-RA 0.099
Vps45 Vacuolar protein sorting 45 0.096
Mlp84B Muscle LIM protein at 84B 0.092
trio CG18214 gene product from transcript CG18214-RA 0.092
put punt 0.092
Fak56D Focal Adhesion Kinase 0.091
cenG1A centaurin gamma 1A 0.089
CG3573 CG3573 gene product from transcript CG3573-RA 0.089
Gug Grunge 0.088
Tm2 Tropomyosin 2 0.087
Apc APC-like 0.087
ed echinoid 0.086
Abi Abelson interacting protein 0.084
RhoGAP93B CG3421 gene product from transcript CG3421-RA 0.084
cpx complexin 0.080
jumu jumeau 0.079
frc fringe connection 0.079
Prp31 CG6876 gene product from transcript CG6876-RA 0.076
Myo31DF Myosin 31DF 0.075
l(2)k16918 lethal (2) k16918 0.075
Vps35 Vacuolar protein sorting 35 0.072
Tsc1 CG6147 gene product from transcript CG6147-RA 0.071
mbt mushroom bodies tiny 0.070
CycA Cyclin A 0.070
NaCP60E Na channel protein 60E 0.070
CG9426 CG9426 gene product from transcript CG9426-RA 0.068
baz bazooka 0.066
mbc myoblast city 0.066
Dlic Dynein light intermediate chain 0.065
Shaw Shaker cognate w 0.064
CG8334 CG8334 gene product from transcript CG8334-RA 0.062
Drl-2 Derailed 2 0.062
jeb jelly belly 0.059
CG6509 CG6509 gene product from transcript CG6509-RB 0.059
Rho1 CG8416 gene product from transcript CG8416-RB 0.058
RanBPM Ran-binding protein M 0.058
rl rolled 0.058
crb crumbs 0.058
Mbs Myosin binding subunit 0.057
Pk61C Protein kinase 61C 0.055
G-ialpha65A G protein alphai subunit 65A 0.054
shark Src homology 2, ankyrin repeat, tyrosine kinase 0.053
yrt yurt 0.053
sls sallimus 0.053
Sbf SET domain binding factor 0.052
bbg big bang 0.052
Act57B Actin 57B 0.052
Gad1 Glutamic acid decarboxylase 1 0.052
kuz kuzbanian 0.051
DAAM Dishevelled Associated Activator of Morphogenesis 0.051
Pli Pellino 0.051
ninaC neither inactivation nor afterpotential C 0.050
CG4853 CG4853 gene product from transcript CG4853-RA 0.050
sax saxophone 0.049
Nmnat Nicotinamide mononucleotide adenylyltransferase 0.049
Sin3A CG8815 gene product from transcript CG8815-RC 0.049
lap like-AP180 0.048
dys dysfusion 0.048
LIMK1 LIM-kinase1 0.048
CG7158 CG7158 gene product from transcript CG7158-RA 0.047
sec10 CG6159 gene product from transcript CG6159-RA 0.047
Ptpmeg CG1228 gene product from transcript CG1228-RD 0.047
klar klarsicht 0.046
drk downstream of receptor kinase 0.046
insc inscuteable 0.046
betaTub56D beta-Tubulin at 56D 0.045
Hr96 Hormone receptor-like in 96 0.045
Tre1 trapped in endoderm-1 0.045
RhoBTB CG5701 gene product from transcript CG5701-RA 0.044
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.992
FGFR2 fibroblast growth factor receptor 2 0.991
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.987
NCF2 neutrophil cytosolic factor 2 0.976
PTK2 PTK2 protein tyrosine kinase 2 0.965
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.965
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.964
SH3KBP1 SH3-domain kinase binding protein 1 0.963
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.939
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.937
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.930
DNM2 dynamin 2 0.913
EGFR epidermal growth factor receptor 0.912
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.912
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.911
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.910
DNM1 dynamin 1 0.907
ITSN1 intersectin 1 (SH3 domain protein) 0.905
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.901
SNX9 sorting nexin 9 0.891
S100A6 S100 calcium binding protein A6 0.864
S100A1 S100 calcium binding protein A1 0.858
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.853
RHOA ras homolog gene family, member A 0.848
FKBP4 FK506 binding protein 4, 59kDa 0.844
RIN3 Ras and Rab interactor 3 0.838
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.828
SH3BP2 SH3-domain binding protein 2 0.817
STAT5A signal transducer and activator of transcription 5A 0.794
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.793
S100A8 S100 calcium binding protein A8 0.786
S100A9 S100 calcium binding protein A9 0.785
OCRL oculocerebrorenal syndrome of Lowe 0.775
GRB7 growth factor receptor-bound protein 7 0.771
S100A11 S100 calcium binding protein A11 0.767
ADRBK1 adrenergic, beta, receptor kinase 1 0.763
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.760
SH3RF1 SH3 domain containing ring finger 1 0.759
SMN1 survival of motor neuron 1, telomeric 0.739
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.738
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.732
NCKAP1 NCK-associated protein 1 0.726
ARRB1 arrestin, beta 1 0.714
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.714
TRAF5 TNF receptor-associated factor 5 0.694
DOCK1 dedicator of cytokinesis 1 0.686
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.681
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.676
ERBB2IP erbb2 interacting protein 0.669
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.665
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.658
BBS10 Bardet-Biedl syndrome 10 0.653
S100B S100 calcium binding protein B 0.648
MYO9B myosin IXB 0.647
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.644
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 0.634
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.623
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.616
JUN jun proto-oncogene 0.608
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.588
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.559
NCF1 neutrophil cytosolic factor 1 0.558
NCK2 NCK adaptor protein 2 0.557
AGAP7 ArfGAP with GTPase domain, ankyrin repeat and PH domain 7 0.548
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.540
PLXNB1 plexin B1 0.538
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.530
SFN stratifin 0.508
NCK1 NCK adaptor protein 1 0.502
RND1 Rho family GTPase 1 0.498
ANKRD28 ankyrin repeat domain 28 0.496
TSC1 tuberous sclerosis 1 0.490
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.489
TSC2 tuberous sclerosis 2 0.489
IGF1R insulin-like growth factor 1 receptor 0.489
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.486
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.484
CCR5 chemokine (C-C motif) receptor 5 0.479
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.476
RGS2 regulator of G-protein signaling 2, 24kDa 0.474
FGFR1 fibroblast growth factor receptor 1 0.465
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.457
RAP1A RAP1A, member of RAS oncogene family 0.456
ILK integrin-linked kinase 0.449
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.440
SYNJ1 synaptojanin 1 0.426
PLXND1 plexin D1 0.424
UNC119 unc-119 homolog (C. elegans) 0.416
BIN1 bridging integrator 1 0.412
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.406
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.404
PRKCA protein kinase C, alpha 0.385
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 0.383
TOR1A torsin family 1, member A (torsin A) 0.383
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.379
S100A4 S100 calcium binding protein A4 0.378
HSPA1B heat shock 70kDa protein 1B 0.373
FMNL1 formin-like 1 0.371
GDI2 GDP dissociation inhibitor 2 0.370
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.944
Akt1 thymoma viral proto-oncogene 1 0.897
Bcl2 B-cell leukemia/lymphoma 2 0.887
Grb2 growth factor receptor bound protein 2 0.881
Arrb2 arrestin, beta 2 0.837
Bax BCL2-associated X protein 0.809
Prkcc protein kinase C, gamma 0.783
Efnb2 ephrin B2 0.760
Plxna1 plexin A1 0.751
Nf1 neurofibromatosis 1 0.746
Kl klotho 0.693
Plxnb1 plexin B1 0.690
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.687
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.629
Braf Braf transforming gene 0.617
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.613
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.606
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.605
Adrbk1 adrenergic receptor kinase, beta 1 0.596
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.586
Epha4 Eph receptor A4 0.563
Sox10 SRY-box containing gene 10 0.558
Dnm1 dynamin 1 0.527
Laptm5 lysosomal-associated protein transmembrane 5 0.523
Git1 G protein-coupled receptor kinase-interactor 1 0.518
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.509
Nf2 neurofibromatosis 2 0.506
Rasgrp2 RAS, guanyl releasing protein 2 0.502
Ntf3 neurotrophin 3 0.502
Anapc2 anaphase promoting complex subunit 2 0.497
Pxn paxillin 0.487
Rac1 RAS-related C3 botulinum substrate 1 0.485
Prkce protein kinase C, epsilon 0.470
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.460
Ilk integrin linked kinase 0.445
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.439
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.422
Arpc4 actin related protein 2/3 complex, subunit 4 0.416
Hmha1 histocompatibility (minor) HA-1 0.410
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.405
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.393
Vav1 vav 1 oncogene 0.390
Selplg selectin, platelet (p-selectin) ligand 0.371
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.354
Arhgap21 Rho GTPase activating protein 21 0.354
Adrb1 adrenergic receptor, beta 1 0.349
Tsc1 tuberous sclerosis 1 0.342
Ephb2 Eph receptor B2 0.340
Src Rous sarcoma oncogene 0.332
Cttn cortactin 0.329
Arrb1 arrestin, beta 1 0.323
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.307
Epha1 Eph receptor A1 0.306
Hdac7 histone deacetylase 7 0.306
Dlg4 discs, large homolog 4 (Drosophila) 0.290
Rhob ras homolog gene family, member B 0.281
Ctnnb1 catenin (cadherin associated protein), beta 1 0.270
Ncf1 neutrophil cytosolic factor 1 0.269
Parva parvin, alpha 0.265
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.259
Map2k2 mitogen-activated protein kinase kinase 2 0.253
Prkcb protein kinase C, beta 0.251
Pnpla2 patatin-like phospholipase domain containing 2 0.250
Cd83 CD83 antigen 0.249
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.248
Cd37 CD37 antigen 0.248
Ccr2 chemokine (C-C motif) receptor 2 0.243
Stag2 stromal antigen 2 0.237
Lrrk2 leucine-rich repeat kinase 2 0.236
Gipc1 GIPC PDZ domain containing family, member 1 0.234
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.234
Nckap1 NCK-associated protein 1 0.229
Rtkn rhotekin 0.229
Cpd carboxypeptidase D 0.227
Itga3 integrin alpha 3 0.224
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.222
Sipa1 signal-induced proliferation associated gene 1 0.221
Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 0.220
Kctd10 potassium channel tetramerisation domain containing 10 0.220
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.219
Wnt7a wingless-related MMTV integration site 7A 0.216
Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5, p101 0.212
Ehmt2 euchromatic histone lysine N-methyltransferase 2 0.210
Tsc2 tuberous sclerosis 2 0.208
Eps15 epidermal growth factor receptor pathway substrate 15 0.205
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.205
Mast3 microtubule associated serine/threonine kinase 3 0.202
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.201
Sirpa signal-regulatory protein alpha 0.198
Plcg1 phospholipase C, gamma 1 0.196
Vasp vasodilator-stimulated phosphoprotein 0.196
Mtap2 microtubule-associated protein 2 0.195
Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.194
Nrbp2 nuclear receptor binding protein 2 0.194
Scn5a sodium channel, voltage-gated, type V, alpha 0.193
Fos FBJ osteosarcoma oncogene 0.192
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.187
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.184
Mgat3 mannoside acetylglucosaminyltransferase 3 0.176
Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.175
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Arl1 ADP-ribosylation factor-like 1 0.141
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.115
Picalm phosphatidylinositol binding clathrin assembly protein 0.111
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.108
Dapk3 death-associated protein kinase 3 0.104
Anxa2 annexin A2 0.101
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.100
Rap1b RAP1B, member of RAS oncogene family 0.097
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.090
Acta2 smooth muscle alpha-actin 0.086
Gria1 glutamate receptor, ionotropic, AMPA 1 0.084
Arpc2 actin related protein 2/3 complex, subunit 2 0.082
Alb albumin 0.076
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.074
Pja2 praja 2, RING-H2 motif containing 0.070
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.070
Epas1 endothelial PAS domain protein 1 0.067
Camk4 calcium/calmodulin-dependent protein kinase IV 0.066
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.065
Pum1 pumilio homolog 1 (Drosophila) 0.065
Apoa1 apolipoprotein A-I 0.065
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.063
Homer1 homer homolog 1 (Drosophila) 0.062
Fgfr1 Fibroblast growth factor receptor 1 0.056
Chrm1 cholinergic receptor, muscarinic 1 0.054
Utrn utrophin 0.054
Gucy1a3 guanylate cyclase 1, soluble, alpha 3 0.053
Amph amphiphysin 0.053
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.051
Dnm2 dynamin 2 0.051
Dnm1 dynamin 1 0.045
Timp1 TIMP metallopeptidase inhibitor 1 0.045
Pld2 phospholipase D2 0.044
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.043
Stxbp1 syntaxin binding protein 1 0.043
Mmp17 matrix metallopeptidase 17 0.043
Lphn2 latrophilin 2 0.042
Shank2 SH3 and multiple ankyrin repeat domains 2 0.042
Inpp5d inositol polyphosphate-5-phosphatase D 0.041
Aif1l allograft inflammatory factor 1-like 0.041
Ncan neurocan 0.041
Pfn1 profilin 1 0.041
LOC293989 cytochrome P450-like 0.041
Pctk1 PCTAIRE protein kinase 1 0.040
Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.040
Kitlg KIT ligand 0.040
Sstr2 somatostatin receptor 2 0.040
Tagln transgelin 0.039
Gria2 glutamate receptor, ionotropic, AMPA 2 0.038
Cfp complement factor properdin 0.038
Copb1 coatomer protein complex, subunit beta 1 0.038
Ddn dendrin 0.038
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.038
Clcn7 chloride channel 7 0.037
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.037
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.036
Ap2a2 adaptor-related protein complex 2, alpha 2 subunit 0.036
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.036
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.036
Necap1 NECAP endocytosis associated 1 0.036
Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.036
Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.036
Hk1 hexokinase 1 0.035
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.035
St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.034
Sept10 septin 10 0.034
Anxa1 annexin A1 0.034
Accn1 amiloride-sensitive cation channel 1, neuronal 0.034
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.034
Adcy5 adenylate cyclase 5 0.033
Slc6a17 solute carrier family 6 (neurotransmitter transporter), member 17 0.033
Mapk3 mitogen activated protein kinase 3 0.032
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.032
Hand2 heart and neural crest derivatives expressed 2 0.032
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.032
Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.032
Akirin2 akirin 2 0.032
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.032
Ppyr1 pancreatic polypeptide receptor 1 0.031
Tas2r119 taste receptor, type 2, member 119 0.031
Fgf7 fibroblast growth factor 7 0.031
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.031
Tek TEK tyrosine kinase, endothelial 0.031
Vcsa1 variable coding sequence A1 0.030
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.030
Rac1 ras-related C3 botulinum toxin substrate 1 0.030
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.030
Myo1d myosin ID 0.030
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.029
Vps52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.029
A4galt alpha 1,4-galactosyltransferase 0.029
Cmklr1 chemokine-like receptor 1 0.028
Prkch protein kinase C, eta 0.028
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.028
Pdcd6 programmed cell death 6 0.028
Mog myelin oligodendrocyte glycoprotein 0.027
Scn5a sodium channel, voltage-gated, type V, alpha subunit 0.027
Arf1 ADP-ribosylation factor 1 0.027
Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 0.027
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.027