The network for 'regulation of nucleotide catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
STE11 Ste11p 0.299
GYL1 Gyl1p 0.259
GCD6 Gcd6p 0.245
STE5 Ste5p 0.224
SUI3 Sui3p 0.211
RHO1 Rho1p 0.201
CDC24 Cdc24p 0.168
ROM2 Rom2p 0.148
IRA1 Ira1p 0.137
MKK1 Mkk1p 0.131
BEM3 Bem3p 0.126
KEL1 Kel1p 0.125
AVO1 Avo1p 0.124
PKC1 Pkc1p 0.101
TOM1 Tom1p 0.095
TRS65 Trs65p 0.094
VTA1 Vta1p 0.091
FKH1 Fkh1p 0.090
GDI1 Gdi1p 0.087
VPS15 Vps15p 0.083
STI1 Sti1p 0.077
GCD7 Gcd7p 0.072
YPT53 Ypt53p 0.071
SPA2 Spa2p 0.067
FAR1 Far1p 0.065
KOG1 Kog1p 0.064
GPB2 Gpb2p 0.063
STE4 Ste4p 0.062
MDS3 Mds3p 0.059
INP52 Inp52p 0.059
BUD6 Bud6p 0.058
FES1 Fes1p 0.057
SEC16 Sec16p 0.056
STE2 Ste2p 0.056
NUP85 Nup85p 0.056
MRS6 Mrs6p 0.056
CCT4 Cct4p 0.053
SLT2 Slt2p 0.052
MOB2 Mob2p 0.051
SSA4 Ssa4p 0.051
PPH21 Pph21p 0.051
STT4 Stt4p 0.050
PEP5 Pep5p 0.049
CDC12 Cdc12p 0.048
YGR250C hypothetical protein 0.048
YNL108C hypothetical protein 0.047
RFC1 Rfc1p 0.047
ABP1 Abp1p 0.046
PTC4 Ptc4p 0.045
PEX29 Pex29p 0.043
YDR348C hypothetical protein 0.043
MYO2 Myo2p 0.043
VPS41 Vps41p 0.042
TSC10 Tsc10p 0.041
SOG2 Sog2p 0.041
BUL1 Bul1p 0.041
CHS1 Chs1p 0.040
PRS2 Prs2p 0.040
GDS1 Gds1p 0.040
RKI1 Rki1p 0.040
CLN3 Cln3p 0.040
STB2 Stb2p 0.039
RGA2 Rga2p 0.039
NOP10 Nop10p 0.039
MBF1 Mbf1p 0.039
PEA2 Pea2p 0.038
SRP54 Srp54p 0.038
BFR1 Bfr1p 0.037
COX13 Cox13p 0.037
MSG5 Msg5p 0.037
HUA2 Hua2p 0.037
DCD1 Dcd1p 0.036
TPK3 Tpk3p 0.036
RRI1 Rri1p 0.036
SWC7 Swc7p 0.035
MCM4 Mcm4p 0.035
BIT61 Bit61p 0.034
INP53 Inp53p 0.034
YIR035C hypothetical protein 0.034
YIP3 Yip3p 0.034
SEC13 Sec13p 0.034
YJL144W hypothetical protein 0.033
YDR186C hypothetical protein 0.033
PPX1 Ppx1p 0.032
VPS74 Vps74p 0.032
STE20 Ste20p 0.032
MYO1 Myo1p 0.032
ITR2 Itr2p 0.032
NEJ1 Nej1p 0.032
BST1 Bst1p 0.031
VPS5 Vps5p 0.031
PPE1 Ppe1p 0.031
PRO3 Pro3p 0.031
YHR127W hypothetical protein 0.031
RUD3 Rud3p 0.031
FIG4 Fig4p 0.031
TPM1 Tpm1p 0.030
HSV2 Hsv2p 0.030
IST1 Ist1p 0.030
URA6 Ura6p 0.030
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.444
unc-45 Protein UNC-45 0.399
gpr-1 Protein GPR-1 0.225
zoo-1 Protein ZOO-1 0.155
etr-1 Protein ETR-1 0.131
rme-4 Protein RME-4 0.130
CELE_F47G4.4 Protein F47G4.4 0.128
M01A8.2 Protein M01A8.2 0.122
flh-2 Protein FLH-2 0.110
F13H6.1 Protein F13H6.1 0.104
CELE_T26A8.4 Protein T26A8.4 0.103
fhod-1 Protein FHOD-1 0.098
sup-17 Protein SUP-17 0.097
unc-26 Protein UNC-26 0.090
rhgf-2 Protein RHGF-2 0.087
egl-18 Protein EGL-18 0.086
daf-19 Protein DAF-19 0.081
lag-1 Protein LAG-1 0.081
inx-1 Protein INX-1 0.080
tmc-2 Protein TMC-2 0.072
snf-1 Protein SNF-1 0.071
Y55F3BR.8 Protein Y55F3BR.8 0.070
sad-1 Protein SAD-1 0.070
rig-6 Protein RIG-6 0.066
mei-1 Protein MEI-1 0.064
let-60 Protein LET-60 0.064
unc-60 Protein UNC-60 0.063
bet-2 Protein BET-2 0.061
cyld-1 Protein CYLD-1 0.057
tpxl-1 Protein TPXL-1 0.054
cah-6 Protein CAH-6 0.052
lin-10 Protein LIN-10 0.052
lin-45 Protein LIN-45 0.052
R10E12.2 Protein R10E12.2 0.051
eor-2 Protein EOR-2 0.050
goa-1 Protein GOA-1 0.048
egl-13 Protein EGL-13 0.047
unc-54 Protein UNC-54 0.047
unc-53 Protein UNC-53 0.045
sel-12 Protein SEL-12 0.045
unc-41 Protein UNC-41 0.045
nrx-1 Protein NRX-1 0.044
unc-79 Protein UNC-79 0.044
stau-1 Protein STAU-1 0.043
H17B01.4 Protein H17B01.4 0.042
pqn-39 Protein PQN-39 0.041
ketn-1 Protein KETN-1 0.041
C53C9.2 Protein C53C9.2 0.040
egl-36 Protein EGL-36 0.040
syd-9 Protein SYD-9 0.040
unc-71 Protein UNC-71 0.040
C11E4.6 Protein C11E4.6 0.040
ZK858.5 Protein ZK858.5 0.039
mpk-1 Protein MPK-1 0.039
skn-1 Protein SKN-1 0.039
ptp-4 Protein PTP-4 0.038
lin-29 Protein LIN-29 0.038
ptp-1 Protein PTP-1 0.038
abl-1 Protein ABL-1 0.037
abts-1 Protein ABTS-1 0.037
elt-6 Protein ELT-6 0.037
ubq-1 Protein UBQ-1 0.036
pat-12 Protein PAT-12 0.036
CELE_F25B4.5 Protein F25B4.5 0.035
Y44E3A.6 Protein Y44E3A.6 0.035
sax-3 Protein SAX-3 0.034
gsa-1 Protein GSA-1 0.034
T21B6.3 Protein T21B6.3 0.034
plc-3 Protein PLC-3 0.034
hmr-1 Protein HMR-1 0.034
rps-2 Protein RPS-2 0.033
mtm-9 Protein MTM-9 0.033
C15H9.5 Protein C15H9.5 0.032
madf-5 Protein MADF-5 0.032
egrh-1 Protein EGRH-1 0.032
egl-23 Protein EGL-23 0.032
CELE_K08E7.6 Protein K08E7.6 0.031
sma-9 Protein SMA-9 0.031
ykt-6 Protein YKT-6 0.031
pqe-1 Protein PQE-1 0.031
coh-3 Protein COH-3 0.030
atg-11 Protein ATG-11 0.030
mig-15 Protein MIG-15 0.030
pat-3 Protein PAT-3 0.030
F32B5.7 Protein F32B5.7 0.029
lin-7 Protein LIN-7 0.029
gpr-2 Protein GPR-2 0.029
T14B1.1 Protein T14B1.1 0.029
pqn-85 Protein PQN-85 0.029
T23F2.2 Protein T23F2.2 0.029
frm-7 Protein FRM-7 0.029
ttx-1 Protein TTX-1 0.028
lev-11 Protein LEV-11 0.028
F39B2.1 Protein F39B2.1 0.028
perm-5 Protein PERM-5 0.028
sli-1 Protein SLI-1 0.028
lim-9 Protein LIM-9 0.028
dgk-4 Protein DGK-4 0.028
mpz-1 Protein MPZ-1 0.028
egl-8 Protein EGL-8 0.028
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Danio rerio
Name Description Probability Func Analog Organism
tnni2a.4 troponin I, skeletal, fast 2a.4 0.876
optc opticin 0.489
tpm4 tropomyosin 4 0.452
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.369
zgc:73142 zgc:73142 0.330
bida BH3 interacting domain death agonist 0.321
plxnb2a plexin b2a 0.308
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.302
tnnt3b troponin T3b, skeletal, fast 0.278
nf1a neurofibromin 1a 0.266
sept7b septin 7b 0.261
mcl1b myeloid cell leukemia sequence 1b 0.241
smyhc2 slow myosin heavy chain 2 0.240
hspa4a heat shock protein 4a 0.217
hspd1 heat shock 60kD protein 1 (chaperonin) 0.208
pvalb4 parvalbumin 4 0.206
rtcd1 RNA terminal phosphate cyclase domain 1 0.202
gna14 guanine nucleotide binding protein (G protein), alpha 14 0.198
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.195
mat2a methionine adenosyltransferase II, alpha 0.192
dnaja1l DnaJ (Hsp40) homolog, subfamily A, member 1, like 0.191
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.186
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.184
tpm3 tropomyosin 3 0.180
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.172
pvalb2 parvalbumin 2 0.170
tnnc1b troponin C type 1b (slow) 0.169
rhoaa ras homolog gene family, member Aa 0.167
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.163
adrb2a adrenergic receptor, beta 2a 0.161
jun jun proto-oncogene 0.158
nf1b neurofibromin 1b 0.155
mcl1a myeloid cell leukemia sequence 1a 0.154
dclk2 doublecortin-like kinase 2 0.154
pparg peroxisome proliferator activated receptor gamma 0.149
hsp90a.2 heat shock protein 90-alpha 2 0.142
neb nebulin 0.141
pdlim5 PDZ and LIM domain 5 0.141
dmbx1a diencephalon/mesencephalon homeobox 1a 0.141
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.139
eomesa eomesodermin homolog a 0.139
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.136
si:ch211-232m7.1 si:ch211-232m7.1 0.135
msna moesin a 0.135
s100a10b S100 calcium binding protein A10b 0.134
phlda2 pleckstrin homology-like domain, family A, member 2 0.133
atf3 activating transcription factor 3 0.131
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.130
zbtb4 zinc finger and BTB domain containing 4 0.125
stc1l stanniocalcin 1, like 0.120
zgc:56548 zgc:56548 0.120
cltca clathrin, heavy polypeptide a (Hc) 0.120
bcl2l10 BCL2-like 10 (apoptosis facilitator) 0.118
scinlb scinderin like b 0.113
tm9sf4 transmembrane 9 superfamily protein member 4 0.112
pdlim1 PDZ and LIM domain 1 (elfin) 0.109
sec24c SEC24 family, member C (S. cerevisiae) 0.108
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.108
hsp70l heat shock cognate 70-kd protein, like 0.107
tnnt2a troponin T2a, cardiac 0.105
limk2 LIM domain kinase 2 0.104
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.102
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.102
rras related RAS viral (r-ras) oncogene homolog 0.101
efna1b ephrin A1b 0.101
tnni1b troponin I, skeletal, slow b 0.101
krt8 keratin 8 0.100
bcl2 B-cell leukemia/lymphoma 2 0.100
ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.098
pvrl1b poliovirus receptor-related 1b 0.097
ldha lactate dehydrogenase A4 0.094
gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.094
gsna gelsolin a 0.093
tm9sf2 transmembrane 9 superfamily member 2 0.092
zgc:56466 zgc:56466 0.090
chac1 ChaC, cation transport regulator-like 1 0.089
ptgs2a prostaglandin-endoperoxide synthase 2a 0.089
epb4.1l4 erythrocyte protein band 4.1-like 4 0.088
cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.088
zgc:101724 zgc:101724 0.085
cars cysteinyl-tRNA synthetase 0.084
p4ha2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2 0.084
ncor1 nuclear receptor co-repressor 1 0.084
stau1 staufen, RNA binding protein, homolog 1 (Drosophila) 0.084
me2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.083
atp1b3a ATPase, Na+/K+ transporting, beta 3a polypeptide 0.083
vdrb vitamin D receptor b 0.083
s100s S100 calcium binding protein S 0.083
prickle2 prickle-like 2 (Drosophila) 0.082
elovl1b elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b 0.082
cnn2 calponin 2 0.081
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.081
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.081
zgc:113625 zgc:113625 0.080
ube2d1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.080
sox4a SRY-box containing gene 4a 0.080
si:dkey-228g21.4 si:dkey-228g21.4 0.080
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.079
gclc glutamate-cysteine ligase, catalytic subunit 0.079
junb jun B proto-oncogene 0.078
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.983
Pten CG5671 gene product from transcript CG5671-RB 0.395
Wnk CG7177 gene product from transcript CG7177-RA 0.325
trio CG18214 gene product from transcript CG18214-RA 0.316
mbc myoblast city 0.276
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.268
Rheb CG1081 gene product from transcript CG1081-RA 0.258
puc puckered 0.253
Pkn Protein kinase related to protein kinase N 0.253
LanA Laminin A 0.249
NaCP60E Na channel protein 60E 0.233
Sos Son of sevenless 0.232
Smox Smad on X 0.202
drk downstream of receptor kinase 0.200
Ephrin CG1862 gene product from transcript CG1862-RA 0.187
rl rolled 0.160
ninaC neither inactivation nor afterpotential C 0.159
stg string 0.159
Tor Target of rapamycin 0.151
Pk61C Protein kinase 61C 0.150
CG17233 CG17233 gene product from transcript CG17233-RA 0.149
Mtl Mig-2-like 0.146
CG11033 CG11033 gene product from transcript CG11033-RB 0.144
CG6509 CG6509 gene product from transcript CG6509-RB 0.140
stai stathmin 0.135
Fak56D Focal Adhesion Kinase 0.121
insc inscuteable 0.121
Khc Kinesin heavy chain 0.120
mask multiple ankyrin repeats single KH domain 0.114
wge winged eye 0.113
phl pole hole 0.113
Stat92E Signal-transducer and activator of transcription protein at 92E 0.108
RhoBTB CG5701 gene product from transcript CG5701-RA 0.107
cno canoe 0.105
inaC inactivation no afterpotential C 0.104
Abi Abelson interacting protein 0.101
synj synaptojanin 0.100
rok Rho-kinase 0.098
Eph Eph receptor tyrosine kinase 0.098
CG8155 CG8155 gene product from transcript CG8155-RA 0.097
pcx pecanex 0.095
plexB plexin B 0.093
siz schizo 0.092
Myo31DF Myosin 31DF 0.091
Pak3 CG14895 gene product from transcript CG14895-RA 0.091
dnc dunce 0.090
p120ctn Adherens junction protein p120 0.087
raps rapsynoid 0.086
cta concertina 0.083
pod1 CG4532 gene product from transcript CG4532-RF 0.083
Rtnl1 CG33113 gene product from transcript CG33113-RF 0.080
sls sallimus 0.080
dos daughter of sevenless 0.080
rap retina aberrant in pattern 0.079
Mad Mothers against dpp 0.078
sn singed 0.078
kuz kuzbanian 0.078
Sbf SET domain binding factor 0.078
XNP CG4548 gene product from transcript CG4548-RA 0.076
mbt mushroom bodies tiny 0.074
l(2)k16918 lethal (2) k16918 0.072
car carnation 0.071
JhI-21 CG12317 gene product from transcript CG12317-RB 0.070
cher cheerio 0.069
Pez CG9493 gene product from transcript CG9493-RA 0.069
RanBPM Ran-binding protein M 0.068
Dap160 Dynamin associated protein 160 0.067
CalpB Calpain-B 0.063
DAAM Dishevelled Associated Activator of Morphogenesis 0.063
Vps45 Vacuolar protein sorting 45 0.062
Prp31 CG6876 gene product from transcript CG6876-RA 0.062
Ced-12 CG5336 gene product from transcript CG5336-RA 0.061
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.061
Rbsn-5 Rabenosyn-5 0.060
Su(H) Suppressor of Hairless 0.060
pho pleiohomeotic 0.060
Rala Ras-related protein 0.058
RpL30 Ribosomal protein L30 0.058
CG7158 CG7158 gene product from transcript CG7158-RA 0.058
Flo-2 flotillin 2 0.057
nwk nervous wreck 0.056
msps mini spindles 0.055
frc fringe connection 0.055
rut rutabaga 0.055
CG2991 CG2991 gene product from transcript CG2991-RA 0.055
Smg1 CG32743 gene product from transcript CG32743-RA 0.053
wupA wings up A 0.052
Mlp84B Muscle LIM protein at 84B 0.051
CG11376 CG11376 gene product from transcript CG11376-RA 0.050
Tab2 TAK1-associated binding protein 2 0.050
blot bloated tubules 0.050
ptc patched 0.050
vav CG7893 gene product from transcript CG7893-RB 0.049
hppy happyhour 0.049
RpL15 Ribosomal protein L15 0.048
bbg big bang 0.048
egl egalitarian 0.047
sima similar 0.047
pyr pyramus 0.046
rhea CG6831 gene product from transcript CG6831-RA 0.046
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
PTK2 PTK2 protein tyrosine kinase 2 0.998
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.995
ARRB1 arrestin, beta 1 0.995
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.994
SFN stratifin 0.990
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.990
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.990
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.988
GRB2 growth factor receptor-bound protein 2 0.986
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.986
BCAR1 breast cancer anti-estrogen resistance 1 0.985
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.976
FGFR2 fibroblast growth factor receptor 2 0.976
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.976
GRB7 growth factor receptor-bound protein 7 0.973
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.967
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.965
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.955
DNM2 dynamin 2 0.955
EGFR epidermal growth factor receptor 0.954
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.954
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.938
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.930
SNX9 sorting nexin 9 0.928
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.925
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.924
PLCG1 phospholipase C, gamma 1 0.920
S100A8 S100 calcium binding protein A8 0.919
FGF1 fibroblast growth factor 1 (acidic) 0.914
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.909
SMN1 survival of motor neuron 1, telomeric 0.906
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.899
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.897
TNNC1 troponin C type 1 (slow) 0.864
NCF2 neutrophil cytosolic factor 2 0.851
RICTOR RPTOR independent companion of MTOR, complex 2 0.850
SH3KBP1 SH3-domain kinase binding protein 1 0.847
BAIAP2 BAI1-associated protein 2 0.847
FGFR1 fibroblast growth factor receptor 1 0.841
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.836
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.815
RIN3 Ras and Rab interactor 3 0.806
ADRBK1 adrenergic, beta, receptor kinase 1 0.806
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.803
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.802
S100A11 S100 calcium binding protein A11 0.785
ABI1 abl-interactor 1 0.777
S100A6 S100 calcium binding protein A6 0.774
TRAF5 TNF receptor-associated factor 5 0.762
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.761
ITSN1 intersectin 1 (SH3 domain protein) 0.746
S100A1 S100 calcium binding protein A1 0.738
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.738
S100B S100 calcium binding protein B 0.696
ANKRD28 ankyrin repeat domain 28 0.690
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.682
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.671
CCR5 chemokine (C-C motif) receptor 5 0.671
HCK hemopoietic cell kinase 0.668
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.660
FMNL1 formin-like 1 0.655
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.654
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.653
RHOA ras homolog gene family, member A 0.649
MYO9B myosin IXB 0.639
SOS1 son of sevenless homolog 1 (Drosophila) 0.633
UNC119 unc-119 homolog (C. elegans) 0.630
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.629
IGF1R insulin-like growth factor 1 receptor 0.628
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.625
SH3RF1 SH3 domain containing ring finger 1 0.624
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.615
RACGAP1 Rac GTPase activating protein 1 0.586
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.582
TSC2 tuberous sclerosis 2 0.581
TMSB4X thymosin beta 4, X-linked 0.567
ARL3 ADP-ribosylation factor-like 3 0.561
ARL2 ADP-ribosylation factor-like 2 0.557
KRT14 keratin 14 0.544
BIN1 bridging integrator 1 0.541
PKN3 protein kinase N3 0.531
HSPA1B heat shock 70kDa protein 1B 0.529
S100A9 S100 calcium binding protein A9 0.529
ARHGAP4 Rho GTPase activating protein 4 0.525
FKBP4 FK506 binding protein 4, 59kDa 0.522
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.519
NCK2 NCK adaptor protein 2 0.494
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.491
OCRL oculocerebrorenal syndrome of Lowe 0.490
PLXND1 plexin D1 0.484
RGS2 regulator of G-protein signaling 2, 24kDa 0.484
RHOC ras homolog gene family, member C 0.475
MPRIP myosin phosphatase Rho interacting protein 0.473
S100A4 S100 calcium binding protein A4 0.473
TNNI1 troponin I type 1 (skeletal, slow) 0.466
MPDZ multiple PDZ domain protein 0.462
RIN1 Ras and Rab interactor 1 0.454
JUN jun proto-oncogene 0.452
TJP2 tight junction protein 2 (zona occludens 2) 0.441
DNM1 dynamin 1 0.441
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.985
Epha4 Eph receptor A4 0.983
Grb2 growth factor receptor bound protein 2 0.957
Efnb2 ephrin B2 0.941
Cbl Casitas B-lineage lymphoma 0.870
Arrb2 arrestin, beta 2 0.861
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.860
Pxn paxillin 0.850
Kl klotho 0.807
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.802
Vav1 vav 1 oncogene 0.787
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.786
Braf Braf transforming gene 0.753
Dnm1 dynamin 1 0.735
Nf1 neurofibromatosis 1 0.726
Bcl2 B-cell leukemia/lymphoma 2 0.719
Akt1 thymoma viral proto-oncogene 1 0.719
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.679
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.674
Rac1 RAS-related C3 botulinum substrate 1 0.665
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.643
Plxnd1 plexin D1 0.642
Ntf3 neurotrophin 3 0.631
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.611
Tubb5 tubulin, beta 5 0.587
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.572
Hmha1 histocompatibility (minor) HA-1 0.572
Prkce protein kinase C, epsilon 0.565
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.556
Eps15 epidermal growth factor receptor pathway substrate 15 0.519
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.516
Plcg1 phospholipase C, gamma 1 0.515
Ldb3 LIM domain binding 3 0.513
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.491
Selplg selectin, platelet (p-selectin) ligand 0.491
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.489
Sox10 SRY-box containing gene 10 0.477
Dock1 dedicator of cytokinesis 1 0.466
Pnpla2 patatin-like phospholipase domain containing 2 0.463
Plxnb1 plexin B1 0.461
Stxbp3a syntaxin binding protein 3A 0.448
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.445
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.432
Tbx2 T-box 2 0.426
Arhgap30 Rho GTPase activating protein 30 0.418
Sh3bp1 SH3-domain binding protein 1 0.415
Rgl2 ral guanine nucleotide dissociation stimulator-like 2 0.412
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.404
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.402
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.396
Vasp vasodilator-stimulated phosphoprotein 0.392
Spry4 sprouty homolog 4 (Drosophila) 0.388
Arpc4 actin related protein 2/3 complex, subunit 4 0.385
Prkcc protein kinase C, gamma 0.378
Igf2 insulin-like growth factor 2 0.371
Casq2 calsequestrin 2 0.370
Plekho2 pleckstrin homology domain containing, family O member 2 0.368
Arhgap21 Rho GTPase activating protein 21 0.362
Bax BCL2-associated X protein 0.352
Tsc1 tuberous sclerosis 1 0.348
Mtap2 microtubule-associated protein 2 0.345
Tnnt3 troponin T3, skeletal, fast 0.344
Tnni2 troponin I, skeletal, fast 2 0.341
Wnt3 wingless-related MMTV integration site 3 0.338
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.335
Rtkn rhotekin 0.331
Hdac7 histone deacetylase 7 0.325
Hrc histidine rich calcium binding protein 0.325
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.313
Adrb1 adrenergic receptor, beta 1 0.313
Epn2 epsin 2 0.311
Gja5 gap junction protein, alpha 5 0.311
Spry2 sprouty homolog 2 (Drosophila) 0.306
Srsf9 serine/arginine-rich splicing factor 9 0.306
Pdgfb platelet derived growth factor, B polypeptide 0.306
Mapkap1 mitogen-activated protein kinase associated protein 1 0.304
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.304
Plxna1 plexin A1 0.295
Trim28 tripartite motif-containing 28 0.294
Adrbk1 adrenergic receptor kinase, beta 1 0.291
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.287
Ctnnb1 catenin (cadherin associated protein), beta 1 0.285
Cxcr4 chemokine (C-X-C motif) receptor 4 0.285
Cd37 CD37 antigen 0.279
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.274
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.270
Plxna3 plexin A3 0.267
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.265
Laptm5 lysosomal-associated protein transmembrane 5 0.258
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.256
Sept9 septin 9 0.253
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.250
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.247
Epha1 Eph receptor A1 0.245
Dock2 dedicator of cyto-kinesis 2 0.243
Nf2 neurofibromatosis 2 0.242
Anapc2 anaphase promoting complex subunit 2 0.236
Nckap1l NCK associated protein 1 like 0.236
Ccl2 chemokine (C-C motif) ligand 2 0.235
Jup junction plakoglobin 0.233
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Anxa2 annexin A2 0.243
Homer1 homer homolog 1 (Drosophila) 0.197
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.186
Prkch protein kinase C, eta 0.151
Tagln transgelin 0.121
Dapk3 death-associated protein kinase 3 0.112
Pja2 praja 2, RING-H2 motif containing 0.109
Myl9 myosin, light chain 9, regulatory 0.104
Pctk1 PCTAIRE protein kinase 1 0.098
Epas1 endothelial PAS domain protein 1 0.096
Sstr1 somatostatin receptor 1 0.087
Scn3b sodium channel, voltage-gated, type III, beta 0.086
Utrn utrophin 0.084
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.083
Acta2 smooth muscle alpha-actin 0.077
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.074
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.071
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.071
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.069
Mcam melanoma cell adhesion molecule 0.069
Cfp complement factor properdin 0.068
Cck cholecystokinin 0.068
Gria2 glutamate receptor, ionotropic, AMPA 2 0.068
Cyth1 cytohesin 1 0.067
Rph3a rabphilin 3A 0.065
Pum1 pumilio homolog 1 (Drosophila) 0.064
Snap25 synaptosomal-associated protein 25 0.063
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.060
Sbf1 SET binding factor 1 0.059
Hk1 hexokinase 1 0.058
Stip1 stress-induced phosphoprotein 1 0.058
Fgf7 fibroblast growth factor 7 0.058
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.056
Strn striatin, calmodulin binding protein 0.056
Cdk5 cyclin-dependent kinase 5 0.055
Zfp260 zinc finger protein 260 0.054
Syn1 synapsin I 0.054
Rab1b RAB1B, member RAS oncogene family 0.053
Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.053
Med23 mediator complex subunit 23 0.053
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.052
Myo1c myosin IC 0.052
Amph amphiphysin 0.051
Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.050
LOC293989 cytochrome P450-like 0.049
Rap1b RAP1B, member of RAS oncogene family 0.049
Map2k2 mitogen activated protein kinase kinase 2 0.049
Egr3 early growth response 3 0.049
Cxcr5 chemokine (C-X-C motif) receptor 5 0.049
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.048
Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 0.048
Unc5b unc-5 homolog B (C. elegans) 0.047
Arpc2 actin related protein 2/3 complex, subunit 2 0.047
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.046
Tgfbr2 transforming growth factor, beta receptor II 0.046
Actg2 actin, gamma 2, smooth muscle, enteric 0.046
Dck deoxycytidine kinase 0.045
Actb actin, beta 0.045
Fgfr1 Fibroblast growth factor receptor 1 0.045
Accn1 amiloride-sensitive cation channel 1, neuronal 0.045
Camk4 calcium/calmodulin-dependent protein kinase IV 0.045
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.044
Dock9 dedicator of cytokinesis 9 0.043
Inpp5j inositol polyphosphate-5-phosphatase J 0.043
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.043
Mllt1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.042
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.042
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.041
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.041
Shank2 SH3 and multiple ankyrin repeat domains 2 0.041
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.041
Fkbp1a FK506 binding protein 1a 0.041
Dlg3 discs, large homolog 3 (Drosophila) 0.041
Sox17 SRY (sex determining region Y)-box 17 0.040
Picalm phosphatidylinositol binding clathrin assembly protein 0.040
Pi4ka phosphatidylinositol 4-kinase, catalytic, alpha 0.040
Sdc3 syndecan 3 0.040
Mapk10 mitogen activated protein kinase 10 0.040
Plcg1 phospholipase C, gamma 1 0.039
Akirin2 akirin 2 0.039
Akap1 A kinase (PRKA) anchor protein 1 0.039
Cngb1 cyclic nucleotide gated channel beta 1 0.039
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.039
Gipc1 GIPC PDZ domain containing family, member 1 0.039
Gpr20 G protein-coupled receptor 20 0.039
Xpnpep1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.039
Copb1 coatomer protein complex, subunit beta 1 0.038
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.038
Cab39 calcium binding protein 39 0.038
Apoa1 apolipoprotein A-I 0.037
Mertk c-mer proto-oncogene tyrosine kinase 0.037
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.037
Arl1 ADP-ribosylation factor-like 1 0.037
Grip1 glutamate receptor interacting protein 1 0.037
Kcns3 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 0.037
Gtf3c1 general transcription factor IIIC, polypeptide 1, alpha 0.037
Vamp3 vesicle-associated membrane protein 3 0.036
Pld2 phospholipase D2 0.036
Actc1 actin, alpha, cardiac muscle 1 0.036
Npy1r neuropeptide Y receptor Y1 0.036