The network for 'regulation of cytoskeleton organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cytoskeleton organization

Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MYO5 Myo5p 0.998
ASK1 Ask1p 0.985
DAM1 Dam1p 0.973
DAD1 Dad1p 0.904
SPC34 Spc34p 0.891
DAD2 Dad2p 0.887
DAD4 Dad4p 0.829
NBP2 Nbp2p 0.822
DUO1 Duo1p 0.786
SAC6 Sac6p 0.764
SSK2 Ssk2p 0.764
TOR1 Tor1p 0.738
BUD6 Bud6p 0.729
FAR1 Far1p 0.699
ARC40 Arc40p 0.689
SPC19 Spc19p 0.674
CDC24 Cdc24p 0.648
ABP1 Abp1p 0.645
DBF2 Dbf2p 0.629
RHO1 Rho1p 0.619
BEM4 Bem4p 0.599
PBS2 Pbs2p 0.582
CDC14 Cdc14p 0.561
SSK1 Ssk1p 0.549
KAR9 Kar9p 0.546
DCP2 Dcp2p 0.494
SPA2 Spa2p 0.474
LSB1 Lsb1p 0.473
ACT1 Act1p 0.446
ARP3 Arp3p 0.443
HOF1 Hof1p 0.437
BUD14 Bud14p 0.418
HSK3 Hsk3p 0.415
CAK1 Cak1p 0.406
CLB4 Clb4p 0.394
BBC1 Bbc1p 0.391
CLN2 Cln2p 0.391
BIM1 Bim1p 0.390
RDI1 Rdi1p 0.389
ARC19 Arc19p 0.377
AVO1 Avo1p 0.375
ARC15 Arc15p 0.372
KIP2 Kip2p 0.342
BOI2 Boi2p 0.327
CLA4 Cla4p 0.302
ARC35 Arc35p 0.291
GIC1 Gic1p 0.280
SHE1 She1p 0.260
KEL1 Kel1p 0.259
VRP1 Vrp1p 0.233
HSL1 Hsl1p 0.233
FPK1 Fpk1p 0.232
BEM1 Bem1p 0.223
DAD3 Dad3p 0.221
CLB3 Clb3p 0.213
BNI1 Bni1p 0.199
SFG1 Sfg1p 0.198
MKK1 Mkk1p 0.195
YSC84 Ysc84p 0.195
CAP2 Cap2p 0.192
CDC20 Cdc20p 0.191
PFY1 Pfy1p 0.187
BZZ1 Bzz1p 0.173
CLN1 Cln1p 0.171
ARP2 Arp2p 0.166
COF1 Cof1p 0.164
PKC1 Pkc1p 0.152
RVS167 Rvs167p 0.150
TWF1 Twf1p 0.148
CIN8 Cin8p 0.146
CKS1 Cks1p 0.145
AFI1 Afi1p 0.143
MSB4 Msb4p 0.135
CDC6 Cdc6p 0.131
ZDS1 Zds1p 0.124
SWE1 Swe1p 0.122
SLA2 Sla2p 0.111
CDC42 Cdc42p 0.109
LTV1 Ltv1p 0.109
BMH1 Bmh1p 0.108
SPC29 Spc29p 0.106
BEM2 Bem2p 0.105
CDC28 Cdc28p 0.105
UGO1 Ugo1p 0.104
SLI15 Sli15p 0.102
CLB1 Clb1p 0.099
DYN1 Dyn1p 0.098
KIP1 Kip1p 0.097
GYL1 Gyl1p 0.095
GIP4 Gip4p 0.094
MCD1 Mcd1p 0.094
MCA1 Mca1p 0.092
BOI1 Boi1p 0.089
IQG1 Iqg1p 0.088
SMI1 Smi1p 0.088
YPK1 Ypk1p 0.087
TPM1 Tpm1p 0.078
ASE1 Ase1p 0.078
YPL014W hypothetical protein 0.076
PPX1 Ppx1p 0.075
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.288
ina-1 Protein INA-1 0.264
unc-15 Protein UNC-15 0.187
R90.1 Protein R90.1 0.171
unc-60 Protein UNC-60 0.165
dsh-2 Protein DSH-2 0.155
egl-8 Protein EGL-8 0.151
alp-1 Protein ALP-1 0.120
par-3 Protein PAR-3 0.115
pry-1 Protein PRY-1 0.111
mig-2 Protein MIG-2 0.110
unc-45 Protein UNC-45 0.110
myo-3 Protein MYO-3 0.110
abts-1 Protein ABTS-1 0.108
ten-1 Protein TEN-1 0.108
sas-4 Protein SAS-4 0.095
eor-1 Protein EOR-1 0.093
casy-1 Protein CASY-1 0.082
sad-1 Protein SAD-1 0.081
gei-18 Protein GEI-18 0.080
K10C3.4 Protein K10C3.4 0.078
C36E8.1 Protein C36E8.1 0.075
hbl-1 Protein HBL-1 0.071
F28E10.1 Protein F28E10.1 0.070
wrm-1 Protein WRM-1 0.066
smg-8 Protein SMG-8 0.065
ZK1098.2 Protein ZK1098.2 0.063
CELE_R06A4.2 Protein R06A4.2 0.063
atl-1 Protein ATL-1 0.061
ifa-1 Protein IFA-1 0.061
CELE_Y67A10A.9 Protein Y67A10A.9 0.061
unc-16 Protein UNC-16 0.061
mtm-3 Protein MTM-3 0.060
ztf-7 Protein ZTF-7 0.058
D1044.2 Protein D1044.2 0.058
let-2 Protein LET-2 0.057
mig-38 Protein MIG-38 0.057
ttm-4 Protein TTM-4 0.056
stau-1 Protein STAU-1 0.056
zyg-9 Protein ZYG-9 0.056
rab-5 Protein RAB-5 0.055
stam-1 Protein STAM-1 0.055
ect-2 Protein ECT-2 0.055
C27H2.2 Protein C27H2.2 0.054
lat-1 Protein LAT-1 0.054
kin-3 Protein KIN-3 0.053
cdf-1 Protein CDF-1 0.052
H43E16.1 Protein H43E16.1 0.052
sax-3 Protein SAX-3 0.051
unc-41 Protein UNC-41 0.051
cdc-42 Protein CDC-42 0.050
kin-4 Protein KIN-4 0.049
lmn-1 Protein LMN-1 0.049
CELE_C08B6.4 Protein C08B6.4 0.048
F36D4.5 Protein F36D4.5 0.047
ifb-2 Protein IFB-2 0.047
R11A8.7 Protein R11A8.7 0.047
CELE_Y45F10B.13 Protein Y45F10B.13 0.047
mup-2 Protein MUP-2 0.046
pkn-1 Protein PKN-1 0.046
unc-53 Protein UNC-53 0.046
let-607 Protein LET-607 0.046
eps-8 Protein EPS-8 0.046
csn-5 Protein CSN-5 0.046
rme-4 Protein RME-4 0.045
afd-1 Protein AFD-1 0.045
skpt-1 Protein SKPT-1 0.044
lin-23 Protein LIN-23 0.044
goa-1 Protein GOA-1 0.043
C16B8.3 Protein C16B8.3 0.043
K06A9.1 Protein K06A9.1 0.043
atn-1 Protein ATN-1 0.043
ztf-22 Protein ZTF-22 0.043
emb-9 Protein EMB-9 0.042
F26E4.7 Protein F26E4.7 0.042
bmk-1 Protein BMK-1 0.042
kal-1 Protein KAL-1 0.042
F25B5.2 Protein F25B5.2 0.042
oma-2 Protein OMA-2 0.041
abcf-2 Protein ABCF-2 0.041
chc-1 Protein CHC-1 0.041
tni-1 Protein TNI-1 0.040
CELE_F47G4.4 Protein F47G4.4 0.040
Y77E11A.1 Protein Y77E11A.1 0.039
sop-2 Protein SOP-2 0.039
fic-1 Protein FIC-1 0.039
CELE_T13H5.1 Protein T13H5.1 0.038
hid-1 Protein HID-1 0.038
rom-1 Protein ROM-1 0.038
par-1 Protein PAR-1 0.038
xpo-1 Protein XPO-1 0.037
ned-8 Protein NED-8 0.037
apl-1 Protein APL-1 0.037
spdl-1 Protein SPDL-1 0.037
par-6 Protein PAR-6 0.036
C29F5.1 Protein C29F5.1 0.036
tbb-4 Protein TBB-4 0.036
T12D8.9 Protein T12D8.9 0.036
F21C10.7 Protein F21C10.7 0.036
E01A2.6 Protein E01A2.6 0.036
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
bactin1 bactin1 0.556
nrp1a neuropilin 1a 0.405
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.295
itgb1b.2 integrin, beta 1b.2 0.282
kdrl kinase insert domain receptor like 0.281
arpc5b actin related protein 2/3 complex, subunit 5B 0.243
cotl1 coactosin-like 1 (Dictyostelium) 0.242
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.233
smyd1b SET and MYND domain containing 1b 0.221
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.212
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.208
mfn2 mitofusin 2 0.191
nphs2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.164
acvr1b activin A receptor, type IB 0.152
pdlim4 PDZ and LIM domain 4 0.131
ret1 receptor tyrosine kinase 0.126
ttk ttk protein kinase 0.123
ldb2a LIM-domain binding factor 2a 0.106
esrrga estrogen-related receptor gamma a 0.104
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.101
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.098
gro2 groucho 2 0.097
pdlim2 PDZ and LIM domain 2 (mystique) 0.095
scinla scinderin like a 0.091
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.091
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.084
plk1 polo-like kinase 1 (Drosophila) 0.080
nusap1 nucleolar and spindle associated protein 1 0.077
flot2a flotillin 2a 0.076
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.075
marcksb myristoylated alanine rich protein kinase C substrate b 0.074
LOC100151531 zinc finger protein Gfi-1b-like 0.074
met met proto-oncogene (hepatocyte growth factor receptor) 0.069
csrp1a cysteine and glycine-rich protein 1a 0.069
kif23 kinesin family member 23 0.068
nadl1.2 neural adhesion molecule L1.2 0.067
dusp6 dual specificity phosphatase 6 0.065
zgc:100942 zgc:100942 0.064
mef2ca myocyte enhancer factor 2ca 0.063
wnt9a wingless-type MMTV integration site family, member 9A 0.059
epb4.1l4 erythrocyte protein band 4.1-like 4 0.058
pnx posterior neuron-specific homeobox 0.058
dscam Down syndrome cell adhesion molecule 0.056
itgb1b integrin, beta 1b 0.056
mef2a myocyte enhancer factor 2a 0.055
tfr1a transferrin receptor 1a 0.054
cdc42 cell division cycle 42 0.054
ttna titin a 0.054
myl9l myosin, light polypeptide 9, like 0.054
cep55l centrosomal protein 55 like 0.052
zff9 zinc finger protein 9 0.051
zeb1 zinc finger E-box binding homeobox 1 0.051
kif14 kinesin family member 14 0.051
krt8 keratin 8 0.051
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.050
hsp90a.1 heat shock protein 90-alpha 1 0.048
gata2a GATA-binding protein 2a 0.048
snx12 sorting nexin 12 0.048
itga2b integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) 0.047
fras1 Fraser syndrome 1 0.047
pak2a p21 (CDKN1A)-activated kinase 2a 0.046
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.045
ptk2.1 protein tyrosine kinase 2a 0.044
prickle1a prickle-like 1 (Drosophila) a 0.044
nbl1 neuroblastoma, suppression of tumorigenicity 1 0.042
gpr126 G protein-coupled receptor 126 0.041
actn1 actinin, alpha 1 0.041
smyd1a SET and MYND domain containing 1a 0.041
ryr3 ryanodine receptor 3 0.041
wasa Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a 0.041
capza1b capping protein (actin filament) muscle Z-line, alpha 1b 0.041
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.041
sh3gl1b SH3-domain GRB2-like 1b 0.041
f2r coagulation factor II (thrombin) receptor 0.040
cdc20 cell division cycle 20 homolog 0.040
itgb1a integrin, beta 1a 0.040
nccrp1 nonspecific cytotoxic cell receptor protein 1 0.039
vasn vasorin 0.039
efnb2a ephrin B2a 0.039
dtl denticleless homolog (Drosophila) 0.039
zbtb4 zinc finger and BTB domain containing 4 0.039
zgc:136263 zgc:136263 0.038
sb:cb81 sb:cb81 0.038
flot1 flotillin 1 0.037
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.037
thy1 Thy-1 cell surface antigen 0.036
csf3r colony stimulating factor 3 receptor (granulocyte) 0.036
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.036
jam2a junctional adhesion molecule 2a 0.035
stac3 SH3 and cysteine rich domain 3 0.034
btk Bruton agammaglobulinemia tyrosine kinase 0.034
gle1 GLE1 RNA export mediator homolog (yeast) 0.034
fli1b friend leukemia integration 1b 0.034
spns2 spinster homolog 2 (Drosophila) 0.034
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.034
tnnc1b troponin C type 1b (slow) 0.034
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.033
zgc:100919 zgc:100919 0.033
rtcd1 RNA terminal phosphate cyclase domain 1 0.032
ptrfb polymerase I and transcript release factor b 0.031
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
chic chickadee 0.978
Rho1 CG8416 gene product from transcript CG8416-RB 0.971
pbl pebble 0.967
Akt1 CG4006 gene product from transcript CG4006-RA 0.947
Ras85D Ras oncogene at 85D 0.930
smt3 CG4494 gene product from transcript CG4494-RA 0.901
sgg shaggy 0.895
katanin-60 katanin 60 0.875
bsk basket 0.852
dia diaphanous 0.841
Dcr-2 Dicer-2 0.821
N Notch 0.821
robo roundabout 0.796
asp abnormal spindle 0.788
ena enabled 0.769
BicD Bicaudal D 0.749
Vrp1 Verprolin 1 0.739
fz frizzled 0.735
rin rasputin 0.731
WASp CG1520 gene product from transcript CG1520-RA 0.726
msn misshapen 0.723
fwd four wheel drive 0.721
baz bazooka 0.678
Arp66B Actin-related protein 66B 0.667
cpb capping protein beta 0.658
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.655
skpA CG16983 gene product from transcript CG16983-RD 0.653
chb chromosome bows 0.644
sls sallimus 0.641
cindr CIN85 and CD2AP orthologue 0.633
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.624
flw flapwing 0.617
Klp67A Kinesin-like protein at 67A 0.608
CycB Cyclin B 0.608
aop anterior open 0.605
rok Rho-kinase 0.599
par-1 CG8201 gene product from transcript CG8201-RA 0.595
Pak3 CG14895 gene product from transcript CG14895-RA 0.593
exo84 CG6095 gene product from transcript CG6095-RA 0.563
egl egalitarian 0.548
polo CG12306 gene product from transcript CG12306-RA 0.545
stck steamer duck 0.541
Arf51F ADP ribosylation factor 51F 0.534
Cdc42 CG12530 gene product from transcript CG12530-RA 0.523
mbt mushroom bodies tiny 0.514
Mical Molecule interacting with CasL 0.508
zip zipper 0.507
tutl turtle 0.502
Zasp52 Z band alternatively spliced PDZ-motif protein 52 0.498
stg string 0.492
CG32038 CG32038 gene product from transcript CG32038-RA 0.488
shot short stop 0.472
smo smoothened 0.471
CadN Cadherin-N 0.470
kst karst 0.469
Lasp CG3849 gene product from transcript CG3849-RB 0.467
Arp14D Actin-related protein 14D 0.465
Rac1 CG2248 gene product from transcript CG2248-RA 0.459
Pak PAK-kinase 0.456
Sos Son of sevenless 0.438
bru brunelleschi 0.432
trc tricornered 0.412
Rab11 Rab-protein 11 0.409
pod1 CG4532 gene product from transcript CG4532-RF 0.406
milt milton 0.400
didum dilute class unconventional myosin 0.386
rhea CG6831 gene product from transcript CG6831-RA 0.383
asl asterless 0.374
Eb1 CG3265 gene product from transcript CG3265-RF 0.371
Det Deterin 0.368
bif bifocal 0.358
Rel Relish 0.357
Rab5 Rab-protein 5 0.346
beta-Spec beta Spectrin 0.342
usp ultraspiracle 0.338
Mtl Mig-2-like 0.330
CG5741 CG5741 gene product from transcript CG5741-RC 0.330
Khc Kinesin heavy chain 0.325
tsr twinstar 0.318
Dap160 Dynamin associated protein 160 0.312
Chc Clathrin heavy chain 0.311
tws twins 0.310
Mer Merlin 0.288
CkIIalpha Casein kinase II alpha subunit 0.283
Fs(2)Ket Female sterile (2) Ketel 0.282
Rac2 CG8556 gene product from transcript CG8556-RA 0.280
mys myospheroid 0.280
Ephrin CG1862 gene product from transcript CG1862-RA 0.279
phl pole hole 0.278
cpa capping protein alpha 0.271
ik2 IkappaB kinase-like 2 0.268
sgl sugarless 0.264
Ten-m Tenascin major 0.263
Actn alpha actinin 0.262
pros prospero 0.260
Cortactin CG3637 gene product from transcript CG3637-RA 0.259
Abl Abl tyrosine kinase 0.258
neur neuralized 0.254
numb CG3779 gene product from transcript CG3779-RB 0.254
robl roadblock 0.253
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
GRB2 growth factor receptor-bound protein 2 0.999
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.998
FLNA filamin A, alpha 0.998
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.997
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.996
SFN stratifin 0.996
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.995
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.995
BAIAP2 BAI1-associated protein 2 0.993
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.992
RHOA ras homolog gene family, member A 0.988
IQGAP1 IQ motif containing GTPase activating protein 1 0.987
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.983
ABI1 abl-interactor 1 0.976
SH3KBP1 SH3-domain kinase binding protein 1 0.975
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.973
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.971
CTTN cortactin 0.968
GAS7 growth arrest-specific 7 0.966
WIPF1 WAS/WASL interacting protein family, member 1 0.963
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.949
FYN FYN oncogene related to SRC, FGR, YES 0.940
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.921
DNM2 dynamin 2 0.916
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.901
GSK3B glycogen synthase kinase 3 beta 0.886
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.884
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.875
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.873
ZNF746 zinc finger protein 746 0.866
S100A6 S100 calcium binding protein A6 0.861
UBC ubiquitin C 0.852
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.840
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.831
ACTN1 actinin, alpha 1 0.829
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.825
ITSN1 intersectin 1 (SH3 domain protein) 0.821
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.814
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.811
FN1 fibronectin 1 0.793
PLEC plectin 0.780
MYH9 myosin, heavy chain 9, non-muscle 0.752
LMNA lamin A/C 0.751
CORO1C coronin, actin binding protein, 1C 0.745
LRRK2 leucine-rich repeat kinase 2 0.745
KIF23 kinesin family member 23 0.744
NCKAP1 NCK-associated protein 1 0.743
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.739
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.733
RAB1A RAB1A, member RAS oncogene family 0.726
SNX9 sorting nexin 9 0.724
NCF1 neutrophil cytosolic factor 1 0.722
VAV1 vav 1 guanine nucleotide exchange factor 0.715
APC adenomatous polyposis coli 0.709
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.704
ARHGAP1 Rho GTPase activating protein 1 0.701
KIF5B kinesin family member 5B 0.688
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.688
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.683
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.666
SOS1 son of sevenless homolog 1 (Drosophila) 0.662
MYL12B myosin, light chain 12B, regulatory 0.658
WASL Wiskott-Aldrich syndrome-like 0.637
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.633
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.610
TSC2 tuberous sclerosis 2 0.607
ITGB4 integrin, beta 4 0.600
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.598
PICALM phosphatidylinositol binding clathrin assembly protein 0.597
S100A11 S100 calcium binding protein A11 0.596
NCF2 neutrophil cytosolic factor 2 0.595
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.579
S100A8 S100 calcium binding protein A8 0.577
FASLG Fas ligand (TNF superfamily, member 6) 0.576
FLNB filamin B, beta 0.560
PDLIM7 PDZ and LIM domain 7 (enigma) 0.555
RNF11 ring finger protein 11 0.541
FNBP1 formin binding protein 1 0.537
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.537
EGFR epidermal growth factor receptor 0.534
TPM4 tropomyosin 4 0.527
NCK1 NCK adaptor protein 1 0.519
SKA1 spindle and kinetochore associated complex subunit 1 0.518
SASS6 spindle assembly 6 homolog (C. elegans) 0.511
ZYX zyxin 0.507
S100A9 S100 calcium binding protein A9 0.496
ATN1 atrophin 1 0.493
CENPE centromere protein E, 312kDa 0.492
SPRR2A small proline-rich protein 2A 0.492
PRKCA protein kinase C, alpha 0.485
ILK integrin-linked kinase 0.485
LGALS1 lectin, galactoside-binding, soluble, 1 0.480
BCAR1 breast cancer anti-estrogen resistance 1 0.473
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.466
EMP3 epithelial membrane protein 3 0.464
ARF6 ADP-ribosylation factor 6 0.453
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.443
CKAP5 cytoskeleton associated protein 5 0.442
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 0.996
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.987
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.971
Apc adenomatosis polyposis coli 0.970
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.966
Rac1 RAS-related C3 botulinum substrate 1 0.951
Efnb2 ephrin B2 0.950
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.939
Trp53 transformation related protein 53 0.930
Pick1 protein interacting with C kinase 1 0.926
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.922
Cbl Casitas B-lineage lymphoma 0.920
Ephb2 Eph receptor B2 0.907
Epha4 Eph receptor A4 0.905
Abi1 abl-interactor 1 0.875
Vasp vasodilator-stimulated phosphoprotein 0.865
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.846
Csf1 colony stimulating factor 1 (macrophage) 0.821
Kit kit oncogene 0.813
Cttn cortactin 0.813
Macf1 microtubule-actin crosslinking factor 1 0.805
Dab1 disabled homolog 1 (Drosophila) 0.792
Ldb3 LIM domain binding 3 0.790
Amhr2 anti-Mullerian hormone type 2 receptor 0.788
Vcl vinculin 0.786
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.785
Ptk2 PTK2 protein tyrosine kinase 2 0.784
Gsk3b glycogen synthase kinase 3 beta 0.777
Nf1 neurofibromatosis 1 0.770
Arpc4 actin related protein 2/3 complex, subunit 4 0.768
Pten phosphatase and tensin homolog 0.766
Plcg1 phospholipase C, gamma 1 0.757
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.743
Capzb capping protein (actin filament) muscle Z-line, beta 0.736
Kif4 kinesin family member 4 0.719
Enah enabled homolog (Drosophila) 0.697
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.692
Src Rous sarcoma oncogene 0.691
Lrrk2 leucine-rich repeat kinase 2 0.682
Prc1 protein regulator of cytokinesis 1 0.675
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.663
Hif1a hypoxia inducible factor 1, alpha subunit 0.654
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.640
Pxn paxillin 0.629
Dok1 docking protein 1 0.598
Gata3 GATA binding protein 3 0.596
Irs1 insulin receptor substrate 1 0.591
Gli3 GLI-Kruppel family member GLI3 0.590
Ptk7 PTK7 protein tyrosine kinase 7 0.586
Lama5 laminin, alpha 5 0.586
Plk1 polo-like kinase 1 (Drosophila) 0.579
Ptch1 patched homolog 1 0.571
Anln anillin, actin binding protein 0.566
Braf Braf transforming gene 0.565
Wdr1 WD repeat domain 1 0.543
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.536
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.528
Ina internexin neuronal intermediate filament protein, alpha 0.521
Prkcb protein kinase C, beta 0.518
Dlg4 discs, large homolog 4 (Drosophila) 0.516
Bcl2 B-cell leukemia/lymphoma 2 0.502
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.492
Itga3 integrin alpha 3 0.488
Sh3kbp1 SH3-domain kinase binding protein 1 0.487
Dock1 dedicator of cytokinesis 1 0.486
Cyld cylindromatosis (turban tumor syndrome) 0.484
Actn2 actinin alpha 2 0.481
Grb2 growth factor receptor bound protein 2 0.472
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.466
Vangl2 vang-like 2 (van gogh, Drosophila) 0.465
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.464
Racgap1 Rac GTPase-activating protein 1 0.460
Inpp5d inositol polyphosphate-5-phosphatase D 0.460
Csrp1 cysteine and glycine-rich protein 1 0.456
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.450
Smad4 MAD homolog 4 (Drosophila) 0.438
Blnk B-cell linker 0.438
Wnt6 wingless-related MMTV integration site 6 0.435
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.433
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.425
Fyn Fyn proto-oncogene 0.424
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.424
Ccna2 cyclin A2 0.418
Fzd1 frizzled homolog 1 (Drosophila) 0.416
Nckap1 NCK-associated protein 1 0.414
Rasa1 RAS p21 protein activator 1 0.405
Zeb1 zinc finger E-box binding homeobox 1 0.398
Gtse1 G two S phase expressed protein 1 0.392
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.383
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.380
Ntf3 neurotrophin 3 0.365
Kif3b kinesin family member 3B 0.364
Reln reelin 0.361
Capn1 calpain 1 0.353
Sox11 SRY-box containing gene 11 0.353
Aspm asp (abnormal spindle)-like, microcephaly associated (Drosophila) 0.350
Rasgrp1 RAS guanyl releasing protein 1 0.347
Tln1 talin 1 0.346
Tgfa transforming growth factor alpha 0.340
Ptprq protein tyrosine phosphatase, receptor type, Q 0.338
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.718
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.332
Efhd2 EF-hand domain family, member D2 0.331
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.296
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.217
Jak2 Janus kinase 2 0.195
Taok1 TAO kinase 1 0.158
Myh9 myosin, heavy chain 9, non-muscle 0.154
Jak1 Janus kinase 1 0.149
Lcp2 lymphocyte cytosolic protein 2 0.147
Acta2 smooth muscle alpha-actin 0.130
Csnk1g3 casein kinase 1, gamma 3 0.126
Arpc2 actin related protein 2/3 complex, subunit 2 0.124
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.118
Cav1 caveolin 1, caveolae protein 0.118
Tagln transgelin 0.109
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.106
Rap1b RAP1B, member of RAS oncogene family 0.105
Dnm1l dynamin 1-like 0.103
Syt4 synaptotagmin IV 0.101
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.098
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.097
Tpm3 tropomyosin 3, gamma 0.092
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 0.091
Sirpa signal-regulatory protein alpha 0.089
Exoc5 exocyst complex component 5 0.088
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.088
Hk1 hexokinase 1 0.085
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.083
Pfn1 profilin 1 0.080
Tacr3 tachykinin receptor 3 0.078
Actg2 actin, gamma 2, smooth muscle, enteric 0.075
Cdk5 cyclin-dependent kinase 5 0.074
Kcnk13 potassium channel, subfamily K, member 13 0.070
Apc adenomatous polyposis coli 0.069
Arf6 ADP-ribosylation factor 6 0.067
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.067
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.066
Wdr1 WD repeat domain 1 0.065
Cd38 CD38 molecule 0.065
Syt8 synaptotagmin VIII 0.065
Agtr1a angiotensin II receptor, type 1a 0.064
Myo1b myosin Ib 0.064
Actb actin, beta 0.062
Opn1sw opsin 1 (cone pigments), short-wave-sensitive 0.061
Dlg1 discs, large homolog 1 (Drosophila) 0.059
Ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.059
Cd37 CD37 molecule 0.059
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.058
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.058
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.056
Actn1 actinin, alpha 1 0.055
Fgfr1 Fibroblast growth factor receptor 1 0.055
Lbr lamin B receptor 0.054
Sri sorcin 0.053
Dgkz diacylglycerol kinase zeta 0.053
Tcf12 transcription factor 12 0.052
Kpnb1 karyopherin (importin) beta 1 0.050
Rhoa ras homolog gene family, member A 0.050
Bcat1 branched chain aminotransferase 1, cytosolic 0.050
Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 0.049
Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult 0.049
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.049
Fmnl1 formin-like 1 0.048
Mapk1 mitogen activated protein kinase 1 0.048
Vegfa vascular endothelial growth factor A 0.048
Shank2 SH3 and multiple ankyrin repeat domains 2 0.048
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.048
Inpp5d inositol polyphosphate-5-phosphatase D 0.046
Nsf N-ethylmaleimide-sensitive factor 0.045
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.045
Gzmk granzyme K 0.044
LOC100362824 caveolin 2-like 0.044
Ptprc protein tyrosine phosphatase, receptor type, C 0.043
Tle4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 0.043
Pitpna phosphatidylinositol transfer protein, alpha 0.043
Cav2 caveolin 2 0.042
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.042
Stk17b serine/threonine kinase 17b 0.041
Cd83 CD83 molecule 0.041
App amyloid beta (A4) precursor protein 0.041
Msn moesin 0.041
Hck hemopoietic cell kinase 0.041
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.041
Gja1 gap junction protein, alpha 1 0.040
Pls3 plastin 3 (T-isoform) 0.040
Chrna6 cholinergic receptor, nicotinic, alpha 6 0.040
Dstn destrin 0.040
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.040
Obp1f odorant binding protein I f 0.040
Pde4b phosphodiesterase 4B, cAMP specific 0.040
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.039
Myh6 myosin, heavy chain 6, cardiac muscle, alpha 0.039
Myo1g myosin IG 0.039
Nrsn1 neurensin 1 0.039
Ndrg4 N-myc downstream regulated gene 4 0.039
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.038
Top2a topoisomerase (DNA) II alpha 0.038
Ptger1 prostaglandin E receptor 1 (subtype EP1) 0.038
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.038