Process View
The network for 'transcription coupled nucleotide excision repair' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
RTF1 | Rtf1p | 0.838 | |
CTR9 | Ctr9p | 0.820 | |
HPR1 | Hpr1p | 0.538 | |
SPT5 | Spt5p | 0.333 | |
SPT16 | Spt16p | 0.242 | |
GBP2 | Gbp2p | 0.241 | |
RPB3 | Rpb3p | 0.234 | |
PAF1 | Paf1p | 0.194 | |
LEO1 | Leo1p | 0.102 | |
DST1 | Dst1p | 0.090 | |
MEX67 | Mex67p | 0.082 | |
SSL1 | Ssl1p | 0.073 | |
RPO21 | Rpo21p | 0.072 | |
THO2 | Tho2p | 0.067 | |
THP2 | Thp2p | 0.063 | |
SUB1 | Sub1p | 0.058 | |
SUS1 | Sus1p | 0.051 | |
NRD1 | Nrd1p | 0.049 | |
HOR2 | Hor2p | 0.042 | |
SPT6 | Spt6p | 0.040 | |
CKA1 | Cka1p | 0.039 | |
TFA1 | Tfa1p | 0.035 | |
PSY4 | Psy4p | 0.034 | |
MSS116 | Mss116p | 0.031 | |
YLR264C-A | hypothetical protein | 0.029 | |
MPT5 | Mpt5p | 0.029 | |
CKB1 | Ckb1p | 0.028 | |
SRD1 | Srd1p | 0.028 | |
LEU2 | Leu2p | 0.027 | |
DED1 | Ded1p | 0.026 | |
IML1 | Iml1p | 0.026 | |
MMS1 | Mms1p | 0.026 | |
HRB1 | Hrb1p | 0.026 | |
BRN1 | Brn1p | 0.025 | |
HXT3 | Hxt3p | 0.024 | |
TEX1 | Tex1p | 0.024 | |
UME1 | Ume1p | 0.023 | |
YLR162W | hypothetical protein | 0.023 | |
APN1 | Apn1p | 0.023 | |
MOT2 | Mot2p | 0.023 | |
ARP10 | Arp10p | 0.023 | |
YOL038C-A | hypothetical protein | 0.023 | |
TYE7 | Tye7p | 0.022 | |
ECM30 | Ecm30p | 0.022 | |
MER1 | Mer1p | 0.022 | |
SWT1 | Swt1p | 0.021 | |
URA3 | Ura3p | 0.021 | |
SPT4 | Spt4p | 0.020 | |
HST3 | Hst3p | 0.020 | |
RAD7 | Rad7p | 0.020 | |
MFT1 | Mft1p | 0.019 | |
HDA2 | Hda2p | 0.019 | |
CAB3 | Cab3p | 0.019 | |
ARG8 | Arg8p | 0.019 | |
HO | Hop | 0.018 | |
YLR042C | hypothetical protein | 0.018 | |
YAR068W | hypothetical protein | 0.018 | |
SEM1 | Sem1p | 0.018 | |
ATP6 | Atp6p | 0.018 | |
OPI1 | Opi1p | 0.018 | |
YIL151C | hypothetical protein | 0.017 | |
SPL2 | Spl2p | 0.017 | |
CUP1-1 | Cup1-1p | 0.017 | |
SWC7 | Swc7p | 0.017 | |
YBR013C | hypothetical protein | 0.017 | |
THP3 | Thp3p | 0.016 | |
YPR157W | hypothetical protein | 0.016 | |
YIR035C | hypothetical protein | 0.016 | |
YLR422W | hypothetical protein | 0.016 | |
RAD18 | Rad18p | 0.016 | |
HMO1 | Hmo1p | 0.016 | |
FMT1 | Fmt1p | 0.016 | |
APL5 | Apl5p | 0.015 | |
STO1 | Sto1p | 0.015 | |
AUA1 | Aua1p | 0.015 | |
HPF1 | Hpf1p | 0.015 | |
GYL1 | Gyl1p | 0.015 | |
OPT2 | Opt2p | 0.015 | |
BSC1 | Bsc1p | 0.015 | |
SPE3 | Spe3p | 0.015 | |
ZPS1 | Zps1p | 0.015 | |
SWD3 | Swd3p | 0.015 | |
CPD1 | Cpd1p | 0.014 | |
RXT3 | Rxt3p | 0.014 | |
TFG1 | Tfg1p | 0.014 | |
ALT2 | Alt2p | 0.014 | |
BAT2 | Bat2p | 0.014 | |
MF(ALPHA)2 | Mf(alpha)2p | 0.014 | |
YKR075C | hypothetical protein | 0.014 | |
YOL013W-A | hypothetical protein | 0.014 | |
CRP1 | Crp1p | 0.014 | |
UPS3 | Ups3p | 0.014 | |
YOL014W | hypothetical protein | 0.014 | |
PCL9 | Pcl9p | 0.014 | |
YNL234W | hypothetical protein | 0.013 | |
ARO10 | Aro10p | 0.013 | |
SCM4 | Scm4p | 0.013 | |
CHA1 | Cha1p | 0.013 | |
RPL41A | Rpl41ap | 0.013 | |
YML003W | hypothetical protein | 0.013 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.957 | |
XAB2 | XPA binding protein 2 | 0.784 | |
POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.773 | |
GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.261 | |
THOC4 | THO complex 4 | 0.181 | |
STRN4 | striatin, calmodulin binding protein 4 | 0.167 | |
DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 0.149 | |
THOC5 | THO complex 5 | 0.114 | |
DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.113 | |
ISY1 | ISY1 splicing factor homolog (S. cerevisiae) | 0.078 | |
SARNP | SAP domain containing ribonucleoprotein | 0.077 | |
GTF2H2 | general transcription factor IIH, polypeptide 2, 44kDa | 0.074 | |
DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | 0.069 | |
THOC1 | THO complex 1 | 0.068 | |
CHTOP | chromatin target of PRMT1 | 0.059 | |
ERCC8 | excision repair cross-complementing rodent repair deficiency, complementation group 8 | 0.049 | |
PPIE | peptidylprolyl isomerase E (cyclophilin E) | 0.026 | |
THOC6 | THO complex 6 homolog (Drosophila) | 0.024 | |
USP11 | ubiquitin specific peptidase 11 | 0.022 | |
RBM8A | RNA binding motif protein 8A | 0.019 | |
TUBA1B | tubulin, alpha 1b | 0.018 | |
XPA | xeroderma pigmentosum, complementation group A | 0.014 | |
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 0.014 | |
CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.013 | |
XPC | xeroderma pigmentosum, complementation group C | 0.013 | |
ZMYND8 | zinc finger, MYND-type containing 8 | 0.012 | |
EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.012 | |
SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.011 | |
RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Srsf9 | serine/arginine-rich splicing factor 9 | 0.674 | |
Ssrp1 | structure specific recognition protein 1 | 0.444 | |
Snrnp40 | small nuclear ribonucleoprotein 40 (U5) | 0.323 | |
Ewsr1 | Ewing sarcoma breakpoint region 1 | 0.282 | |
Rnps1 | ribonucleic acid binding protein S1 | 0.247 | |
Srrt | serrate RNA effector molecule homolog (Arabidopsis) | 0.247 | |
Prmt1 | protein arginine N-methyltransferase 1 | 0.230 | |
Anp32b | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.201 | |
Trim28 | tripartite motif-containing 28 | 0.177 | |
Hnrnpab | heterogeneous nuclear ribonucleoprotein A/B | 0.157 | |
Ppm1g | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 0.154 | |
Ran | RAN, member RAS oncogene family | 0.126 | |
Eftud2 | elongation factor Tu GTP binding domain containing 2 | 0.115 | |
Thoc4 | THO complex 4 | 0.114 | |
Tdg | thymine DNA glycosylase | 0.104 | |
Ptma | prothymosin alpha | 0.093 | |
Fbl | fibrillarin | 0.089 | |
Gar1 | GAR1 ribonucleoprotein homolog (yeast) | 0.082 | |
Pabpn1 | poly(A) binding protein, nuclear 1 | 0.079 | |
Nup93 | nucleoporin 93 | 0.066 | |
Impdh2 | inosine 5'-phosphate dehydrogenase 2 | 0.053 | |
Acin1 | apoptotic chromatin condensation inducer 1 | 0.053 | |
Banf1 | barrier to autointegration factor 1 | 0.052 | |
Cct3 | chaperonin containing Tcp1, subunit 3 (gamma) | 0.051 | |
Ppp4c | protein phosphatase 4, catalytic subunit | 0.047 | |
Srsf2 | serine/arginine-rich splicing factor 2 | 0.047 | |
Tuba1b | tubulin, alpha 1B | 0.043 | |
1500001M20Rik | RIKEN cDNA 1500001M20 gene | 0.042 | |
Rcc2 | regulator of chromosome condensation 2 | 0.041 | |
Ranbp1 | RAN binding protein 1 | 0.040 | |
Safb | scaffold attachment factor B | 0.039 | |
Cdk9 | cyclin-dependent kinase 9 (CDC2-related kinase) | 0.039 | |
Sf3b3 | splicing factor 3b, subunit 3 | 0.038 | |
U2af1 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 | 0.037 | |
Set | SET nuclear oncogene | 0.035 | |
Eif3g | eukaryotic translation initiation factor 3, subunit G | 0.035 | |
Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.035 | |
Cct2 | chaperonin containing Tcp1, subunit 2 (beta) | 0.034 | |
Hnrnpm | heterogeneous nuclear ribonucleoprotein M | 0.033 | |
Refbp2 | RNA and export factor binding protein 2 | 0.032 | |
A430005L14Rik | RIKEN cDNA A430005L14 gene | 0.032 | |
Senp3 | SUMO/sentrin specific peptidase 3 | 0.032 | |
Apex1 | apurinic/apyrimidinic endonuclease 1 | 0.031 | |
Gtf2f1 | general transcription factor IIF, polypeptide 1 | 0.029 | |
Eif4a3 | eukaryotic translation initiation factor 4A3 | 0.029 | |
Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.029 | |
Lsm2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.029 | |
Nup107 | nucleoporin 107 | 0.027 | |
Srsf4 | serine/arginine-rich splicing factor 4 | 0.027 | |
Ddx54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 | 0.026 | |
Ncl | nucleolin | 0.026 | |
Puf60 | poly-U binding splicing factor 60 | 0.025 | |
Ipo5 | importin 5 | 0.024 | |
Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.024 | |
Rbm14 | RNA binding motif protein 14 | 0.023 | |
Nup62 | nucleoporin 62 | 0.023 | |
Tbcb | tubulin folding cofactor B | 0.023 | |
Cks1b | CDC28 protein kinase 1b | 0.023 | |
Cdk2ap1 | CDK2 (cyclin-dependent kinase 2)-associated protein 1 | 0.022 | |
Cpsf1 | cleavage and polyadenylation specific factor 1 | 0.022 | |
Ctps | cytidine 5'-triphosphate synthase | 0.022 | |
Nxt1 | NTF2-related export protein 1 | 0.021 | |
Tubb5 | tubulin, beta 5 | 0.021 | |
Ncbp1 | nuclear cap binding protein subunit 1 | 0.021 | |
Prpf8 | pre-mRNA processing factor 8 | 0.021 | |
Cdk4 | cyclin-dependent kinase 4 | 0.020 | |
Hn1 | hematological and neurological expressed sequence 1 | 0.019 | |
Cdca4 | cell division cycle associated 4 | 0.018 | |
Dtymk | deoxythymidylate kinase | 0.018 | |
Taf5l | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor | 0.018 | |
Xab2 | XPA binding protein 2 | 0.018 | |
2700094K13Rik | RIKEN cDNA 2700094K13 gene | 0.017 | |
Enoph1 | enolase-phosphatase 1 | 0.017 | |
Nop56 | NOP56 ribonucleoprotein homolog (yeast) | 0.017 | |
Snrpa | small nuclear ribonucleoprotein polypeptide A | 0.017 | |
U2af2 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 | 0.016 | |
Sltm | SAFB-like, transcription modulator | 0.016 | |
Qrich1 | glutamine-rich 1 | 0.016 | |
Ppan | peter pan homolog (Drosophila) | 0.016 | |
Odc1 | ornithine decarboxylase, structural 1 | 0.016 | |
Sfpq | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) | 0.016 | |
H2afy | H2A histone family, member Y | 0.015 | |
Ppp1r8 | protein phosphatase 1, regulatory (inhibitor) subunit 8 | 0.015 | |
2310036O22Rik | RIKEN cDNA 2310036O22 gene | 0.015 | |
Eif3c | eukaryotic translation initiation factor 3, subunit C | 0.015 | |
Brd2 | bromodomain containing 2 | 0.015 | |
Rbm10 | RNA binding motif protein 10 | 0.015 | |
Hnrnpd | heterogeneous nuclear ribonucleoprotein D | 0.014 | |
Cherp | calcium homeostasis endoplasmic reticulum protein | 0.014 | |
Pprc1 | peroxisome proliferative activated receptor, gamma, coactivator-related 1 | 0.014 | |
Noc4l | nucleolar complex associated 4 homolog (S. cerevisiae) | 0.014 | |
Cox4nb | COX4 neighbor | 0.014 | |
Siva1 | SIVA1, apoptosis-inducing factor | 0.014 | |
Rbmxrt | RNA binding motif protein, X chromosome retrogene | 0.014 | |
Dhx16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 0.014 | |
Fam192a | family with sequence similarity 192, member A | 0.014 | |
Pa2g4 | proliferation-associated 2G4 | 0.014 | |
Nxf1 | nuclear RNA export factor 1 homolog (S. cerevisiae) | 0.014 | |
Gtf3c2 | general transcription factor IIIC, polypeptide 2, beta | 0.014 | |
Pcbp1 | poly(rC) binding protein 1 | 0.013 |