The network for 'chromatin modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chromatin modification

The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HHT1 Hht1p 1.000
SIN3 Sin3p 0.999
ADA2 Ada2p 0.999
RSC4 Rsc4p 0.999
TRA1 Tra1p 0.998
BDF1 Bdf1p 0.997
SWR1 Swr1p 0.996
GCN5 Gcn5p 0.996
HTZ1 Htz1p 0.996
VPS72 Vps72p 0.995
SET1 Set1p 0.994
ISW1 Isw1p 0.994
ARP4 Arp4p 0.994
YAF9 Yaf9p 0.988
SUS1 Sus1p 0.987
ASF1 Asf1p 0.987
SWD3 Swd3p 0.985
SPT20 Spt20p 0.984
SPT7 Spt7p 0.981
TAF6 Taf6p 0.981
SPT8 Spt8p 0.981
RTF1 Rtf1p 0.981
SIR2 Sir2p 0.978
SET2 Set2p 0.977
HFI1 Hfi1p 0.974
NGG1 Ngg1p 0.974
NPL6 Npl6p 0.974
SWC3 Swc3p 0.973
UBP8 Ubp8p 0.972
SGF73 Sgf73p 0.971
VPS71 Vps71p 0.967
YNG2 Yng2p 0.964
EPL1 Epl1p 0.964
YTA7 Yta7p 0.959
HHO1 Hho1p 0.959
RSC1 Rsc1p 0.955
RSC58 Rsc58p 0.953
EAF5 Eaf5p 0.951
STH1 Sth1p 0.949
SGF29 Sgf29p 0.948
RSC8 Rsc8p 0.945
SDC1 Sdc1p 0.943
SPT3 Spt3p 0.939
SWD1 Swd1p 0.930
HDA1 Hda1p 0.924
TAF14 Taf14p 0.923
RSC2 Rsc2p 0.922
ESA1 Esa1p 0.921
MOT1 Mot1p 0.903
SET3 Set3p 0.892
SWC5 Swc5p 0.873
SUM1 Sum1p 0.869
RSC6 Rsc6p 0.867
RCO1 Rco1p 0.844
SWC4 Swc4p 0.836
RSC3 Rsc3p 0.820
RVB2 Rvb2p 0.804
SPT10 Spt10p 0.802
CDC28 Cdc28p 0.772
ARP9 Arp9p 0.769
SWI4 Swi4p 0.767
ARP6 Arp6p 0.760
SNT1 Snt1p 0.750
ARP8 Arp8p 0.739
RPD3 Rpd3p 0.732
RTT106 Rtt106p 0.716
BRE2 Bre2p 0.707
UBP6 Ubp6p 0.706
ISW2 Isw2p 0.679
EAF3 Eaf3p 0.677
TAF5 Taf5p 0.669
SNF5 Snf5p 0.651
HDA3 Hda3p 0.644
ITC1 Itc1p 0.639
HOS2 Hos2p 0.634
EAF1 Eaf1p 0.622
ARP7 Arp7p 0.616
BRE1 Bre1p 0.609
LEO1 Leo1p 0.607
SAP190 Sap190p 0.592
HIR2 Hir2p 0.588
RPN4 Rpn4p 0.587
SPT15 Spt15p 0.577
SIR3 Sir3p 0.577
CHD1 Chd1p 0.576
HMO1 Hmo1p 0.571
RSC9 Rsc9p 0.552
SWI1 Swi1p 0.548
CLB2 Clb2p 0.543
ELP4 Elp4p 0.543
SWI5 Swi5p 0.542
ESF1 Esf1p 0.529
CAC2 Cac2p 0.510
SAS3 Sas3p 0.503
SNF2 Snf2p 0.498
SPP1 Spp1p 0.493
UBP3 Ubp3p 0.488
HTL1 Htl1p 0.488
AHC1 Ahc1p 0.456
RFX1 Rfx1p 0.451
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
his-5 Protein HIS-5 0.692
his-1 Protein HIS-1 0.606
attf-2 Protein ATTF-2 0.527
zyg-9 Protein ZYG-9 0.361
F33E11.3 Protein F33E11.3 0.351
F59E12.11 Protein F59E12.11 0.313
his-46 Protein HIS-46 0.307
lin-35 Protein LIN-35 0.294
apr-1 Protein APR-1 0.288
Y87G2A.1 Protein Y87G2A.1 0.258
ran-1 Protein RAN-1 0.237
map-2 Protein MAP-2 0.228
kle-2 Protein KLE-2 0.203
set-1 Protein SET-1 0.197
bub-1 Protein BUB-1 0.196
his-64 Protein HIS-64 0.193
spr-5 Protein SPR-5 0.189
vab-1 Protein VAB-1 0.187
F33H2.3 Protein F33H2.3 0.187
his-31 Protein HIS-31 0.181
mix-1 Protein MIX-1 0.166
T20F7.1 Protein T20F7.1 0.165
npp-2 Protein NPP-2 0.163
D1081.8 Protein D1081.8 0.160
nfya-1 Protein NFYA-1 0.158
brf-1 Protein BRF-1 0.158
wrm-1 Protein WRM-1 0.156
smp-1 Protein SMP-1 0.155
ZK328.4 Protein ZK328.4 0.149
his-50 Protein HIS-50 0.149
hda-2 Protein HDA-2 0.149
trr-1 Protein TRR-1 0.139
skp-1 Protein SKP-1 0.139
T02G5.12 Protein T02G5.12 0.133
let-418 Protein LET-418 0.118
F33H1.4 Protein F33H1.4 0.112
sdc-1 Protein SDC-1 0.110
bmk-1 Protein BMK-1 0.107
unc-37 Protein UNC-37 0.106
cec-5 Protein CEC-5 0.102
hmp-1 Protein HMP-1 0.101
unc-40 Protein UNC-40 0.100
dcr-1 Protein DCR-1 0.099
his-16 Protein HIS-16 0.098
C27A12.7 Protein C27A12.7 0.098
npp-21 Protein NPP-21 0.097
dpl-1 Protein DPL-1 0.095
Y32B12B.2 Protein Y32B12B.2 0.092
ada-2 Protein ADA-2 0.091
F35G12.4 Protein F35G12.4 0.091
T18D3.1 Protein T18D3.1 0.091
sip-1 Protein SIP-1 0.091
hcp-4 Protein HCP-4 0.090
sta-1 Protein STA-1 0.089
egl-27 Protein EGL-27 0.085
mes-4 Protein MES-4 0.084
pqn-59 Protein PQN-59 0.082
ttm-4 Protein TTM-4 0.081
mep-1 Protein MEP-1 0.078
nasp-1 Protein NASP-1 0.077
his-38 Protein HIS-38 0.076
F54C9.9 Protein F54C9.9 0.076
nhr-49 Protein NHR-49 0.075
pqn-65 Protein PQN-65 0.075
rpn-1 Protein RPN-1 0.075
spd-1 Protein SPD-1 0.074
usp-46 Protein USP-46 0.073
crn-3 Protein CRN-3 0.073
hda-1 Protein HDA-1 0.073
C34D10.2 Protein C34D10.2 0.072
F28B3.1 Protein F28B3.1 0.072
hcp-3 Protein HCP-3 0.071
hlh-1 Protein HLH-1 0.070
F55A3.3 Protein F55A3.3 0.069
iff-1 Protein IFF-1 0.069
rgr-1 Protein RGR-1 0.069
asd-1 Protein ASD-1 0.067
capg-1 Protein CAPG-1 0.065
swsn-2.1 Protein SWSN-2.1 0.065
B0336.3 Protein B0336.3 0.063
bed-1 Protein BED-1 0.063
CELE_F19F10.9 Protein F19F10.9 0.062
gei-4 Protein GEI-4 0.062
htz-1 Protein HTZ-1 0.061
nhr-2 Protein NHR-2 0.061
B0336.5 Protein B0336.5 0.061
Y17G7B.17 Protein Y17G7B.17 0.060
vrk-1 Protein VRK-1 0.059
lin-25 Protein LIN-25 0.059
crn-1 Protein CRN-1 0.059
let-504 Protein LET-504 0.058
bli-4 Protein BLI-4 0.057
hmg-4 Protein HMG-4 0.056
pde-2 Protein PDE-2 0.056
dnj-11 Protein DNJ-11 0.056
orc-5 Protein ORC-5 0.056
egl-18 Protein EGL-18 0.056
met-1 Protein MET-1 0.055
ddx-23 Protein DDX-23 0.055
ppfr-2 Protein PPFR-2 0.054
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
pcna proliferating cell nuclear antigen 0.920
mll4b myeloid/lymphoid or mixed-lineage leukemia 4b 0.853
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.749
setdb1a SET domain, bifurcated 1a 0.718
ube2i ubiquitin-conjugating enzyme E2I 0.666
gro1 groucho 1 0.653
suv39h1a suppressor of variegation 3-9 homolog 1a 0.612
smyd2a SET and MYND domain containing 2a 0.567
setdb1b SET domain, bifurcated 1b 0.535
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.508
ehmt1a euchromatic histone-lysine N-methyltransferase 1a 0.474
setd5 SET domain containing 5 0.429
hdac1 histone deacetylase 1 0.421
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.395
suv39h1b suppressor of variegation 3-9 homolog 1b 0.376
myf5 myogenic factor 5 0.372
whsc1l1 Wolf-Hirschhorn syndrome candidate 1-like 1 0.349
setd2 SET domain containing 2 0.337
prdm9 PR domain containing 9 0.321
prdm2b PR domain containing 2, with ZNF domain b 0.309
ehmt1b euchromatic histone-lysine N-methyltransferase 1b 0.293
nasp nuclear autoantigenic sperm protein (histone-binding) 0.289
suv420h1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.283
ehmt2 euchromatic histone-lysine N-methyltransferase 2 0.283
mll4a myeloid/lymphoid or mixed-lineage leukemia 4a 0.274
pax7a paired box gene 7a 0.269
ggnbp2 gametogenetin binding protein 2 0.256
ssrp1a structure specific recognition protein 1a 0.254
prdm11 PR domain containing 11 0.251
smyd3 SET and MYND domain containing 3 0.233
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.231
smyd1a SET and MYND domain containing 1a 0.229
smc3 structural maintenance of chromosomes 3 0.216
fen1 flap structure-specific endonuclease 1 0.213
foxd3 forkhead box D3 0.210
myog myogenin 0.209
rcc2 regulator of chromosome condensation 2 0.198
ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.194
mll2 myeloid/lymphoid or mixed-lineage leukemia 2 0.190
prdm4 PR domain containing 4 0.180
setd8b SET domain containing (lysine methyltransferase) 8b 0.179
zgc:174506 zgc:174506 0.178
ankrd12 ankyrin repeat domain 12 0.173
orc1 origin recognition complex, subunit 1 0.169
nsd1b nuclear receptor binding SET domain protein 1b 0.167
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.167
prdm8b PR domain containing 8b 0.154
smyd5 SMYD family member 5 0.149
brd4 bromodomain containing 4 0.147
phf6 PHD finger protein 6 0.147
slc7a6os solute carrier family 7, member 6 opposite strand 0.144
znf703 zinc finger protein 703 0.126
pbrm1l polybromo 1, like 0.125
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.114
nvl nuclear VCP-like 0.114
brd3a bromodomain containing 3a 0.114
diexf digestive organ expansion factor homolog 0.114
suv420h2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.111
rbm17 RNA binding motif protein 17 0.106
myod1 myogenic differentiation 1 0.103
phf2 PHD finger protein 2 0.102
ncapd2 non-SMC condensin I complex, subunit D2 0.098
setd8a SET domain containing (lysine methyltransferase) 8a 0.098
prdm1b PR domain containing 1b, with ZNF domain 0.097
snrpc small nuclear ribonucleoprotein polypeptide C 0.096
nrp1b neuropilin 1b 0.093
akap12b A kinase (PRKA) anchor protein (gravin) 12b 0.093
myst2 MYST histone acetyltransferase 2 0.092
hoxa9a homeo box A9a 0.090
xbp1 X-box binding protein 1 0.089
mstna myostatin a 0.089
sass6 spindle assembly 6 homolog (C. elegans) 0.088
prp19 PRP19/PSO4 homolog (S. cerevisiae) 0.087
hmgb3a high-mobility group box 3a 0.086
dnmt3 DNA (cytosine-5-)-methyltransferase 3 0.084
tardbp TAR DNA binding protein 0.083
marcksb myristoylated alanine rich protein kinase C substrate b 0.079
rbb4l retinoblastoma binding protein 4, like 0.079
eef2k elongation factor-2 kinase 0.078
tfip11 tuftelin interacting protein 11 0.077
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.077
anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.076
brd8 bromodomain containing 8 0.076
si:ch211-57k11.10 si:ch211-57k11.10 0.075
rarga retinoic acid receptor gamma a 0.074
hsp90a.1 heat shock protein 90-alpha 1 0.071
dag1 dystroglycan 1 0.069
rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.069
prickle2 prickle-like 2 (Drosophila) 0.068
sirt6 sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) 0.068
sephs1 selenophosphate synthetase 1 0.067
exosc6 exosome component 6 0.067
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.066
trim71 tripartite motif-containing 71 0.066
cry1a cryptochrome 1a 0.066
cse1l chromosome segregation 1-like (S. cerevisiae) 0.065
saal1 serum amyloid A-like 1 0.064
morf4l1 mortality factor 4 like 1 0.064
prdm14 PR domain containing 14 0.064
nrp1a neuropilin 1a 0.063
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Snr1 Snf5-related 1 0.998
dik diskette 0.995
Su(var)3-3 Suppressor of variegation 3-3 0.990
Dref DNA replication-related element factor 0.982
Sir2 CG5216 gene product from transcript CG5216-RA 0.969
Hcf Host cell factor 0.965
brm brahma 0.958
Mad Mothers against dpp 0.935
mof males absent on the first 0.892
Rpd3 CG7471 gene product from transcript CG7471-RA 0.891
gro groucho 0.878
BEAF-32 Boundary element-associated factor of 32kD 0.871
trx trithorax 0.868
SMC2 CG10212 gene product from transcript CG10212-RA 0.852
lok loki 0.849
Smr Smrter 0.849
lwr lesswright 0.847
jumu jumeau 0.839
Atac1 ATAC component 1 0.815
egg eggless 0.802
mod(mdg4) modifier of mdg4 0.796
Pp1-87B Protein phosphatase 1 at 87B 0.777
Caf1 Chromatin assembly factor 1 subunit 0.766
CG3363 CG3363 gene product from transcript CG3363-RB 0.754
Su(var)2-10 Suppressor of variegation 2-10 0.751
p53 CG33336 gene product from transcript CG33336-RB 0.740
Scm Sex comb on midleg 0.732
mi minus 0.720
Pcaf CG4107 gene product from transcript CG4107-RA 0.702
BRWD3 CG31132 gene product from transcript CG31132-RA 0.701
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.701
ph-d polyhomeotic distal 0.692
tws twins 0.685
Su(var)2-HP2 CG12864 gene product from transcript CG12864-RB 0.680
CG10414 CG10414 gene product from transcript CG10414-RA 0.671
msl-3 male-specific lethal 3 0.646
CTCF CG8591 gene product from transcript CG8591-RA 0.636
Akt1 CG4006 gene product from transcript CG4006-RA 0.621
Bgb Big brother 0.620
D1 D1 chromosomal protein 0.606
polo CG12306 gene product from transcript CG12306-RA 0.595
Pcl Polycomblike 0.583
Mocs2 Molybdopterin synthase 2 0.575
Su(var)205 Suppressor of variegation 205 0.570
Rga Regena 0.570
CG5720 CG5720 gene product from transcript CG5720-RA 0.558
Ada2b CG9638 gene product from transcript CG9638-RA 0.550
zf30C Zinc finger protein 30C 0.539
Jarid2 CG3654 gene product from transcript CG3654-RD 0.528
D12 CG13400 gene product from transcript CG13400-RA 0.523
SelD Selenide,water dikinase 0.509
dm diminutive 0.504
mxc multi sex combs 0.499
Suv4-20 CG13363 gene product from transcript CG13363-RA 0.493
Bap170 Brahma associated protein 170kD 0.490
fzy fizzy 0.489
Iswi Imitation SWI 0.488
E(z) Enhancer of zeste 0.482
CG4266 CG4266 gene product from transcript CG4266-RA 0.476
sna snail 0.460
His2Av Histone H2A variant 0.458
Su(var)3-7 Suppressor of variegation 3-7 0.457
BCL7-like CG17252 gene product from transcript CG17252-RA 0.455
wapl wings apart-like 0.452
scny scrawny 0.449
Rca1 Regulator of cyclin A1 0.440
wds will die slowly 0.437
kis kismet 0.412
wdn wings down 0.404
hyx hyrax 0.402
CstF-50 CG2261 gene product from transcript CG2261-RA 0.400
puc puckered 0.394
Nup98 Nucleoporin 98 0.387
ash2 absent, small, or homeotic discs 2 0.383
hth homothorax 0.383
MRG15 CG6363 gene product from transcript CG6363-RA 0.367
CycT Cyclin T 0.361
nkd naked cuticle 0.359
Adf1 Adh transcription factor 1 0.354
Hr39 Hormone receptor-like in 39 0.352
asp abnormal spindle 0.350
CSN4 COP9 complex homolog subunit 4 0.349
U2af38 U2 small nuclear riboprotein auxiliary factor 38 0.344
Top2 Topoisomerase 2 0.342
sxc super sex combs 0.340
cg combgap 0.335
Su(H) Suppressor of Hairless 0.329
slmb supernumerary limbs 0.325
e(y)1 enhancer of yellow 1 0.324
Sgf29 CG30390 gene product from transcript CG30390-RA 0.320
Saf6 SAGA factor-like TAF6 0.315
CG1347 CG1347 gene product from transcript CG1347-RB 0.314
plu plutonium 0.309
morgue modifier of rpr and grim, ubiquitously expressed 0.306
Pka-C1 cAMP-dependent protein kinase 1 0.306
HP1c CG6990 gene product from transcript CG6990-RA 0.305
smt3 CG4494 gene product from transcript CG4494-RA 0.299
cdc2c CG10498 gene product from transcript CG10498-RC 0.294
NC2beta CG4185 gene product from transcript CG4185-RA 0.292
tld tolloid 0.292
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
HDAC2 histone deacetylase 2 1.000
WDR5 WD repeat domain 5 1.000
HDAC1 histone deacetylase 1 1.000
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 1.000
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.000
CREBBP CREB binding protein 1.000
KDM1A lysine (K)-specific demethylase 1A 1.000
NCOR1 nuclear receptor corepressor 1 1.000
YY1 YY1 transcription factor 1.000
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.000
H2AFX H2A histone family, member X 1.000
SIN3A SIN3 homolog A, transcription regulator (yeast) 1.000
ESR1 estrogen receptor 1 1.000
BRCA1 breast cancer 1, early onset 1.000
RB1 retinoblastoma 1 1.000
HCFC1 host cell factor C1 (VP16-accessory protein) 1.000
TRRAP transformation/transcription domain-associated protein 1.000
ACTL6A actin-like 6A 1.000
MAPK14 mitogen-activated protein kinase 14 1.000
HIST1H3B histone cluster 1, H3b 1.000
RUVBL1 RuvB-like 1 (E. coli) 1.000
EP300 E1A binding protein p300 1.000
PARP1 poly (ADP-ribose) polymerase 1 1.000
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 1.000
KAT2A K(lysine) acetyltransferase 2A 1.000
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.000
RBBP4 retinoblastoma binding protein 4 1.000
EED embryonic ectoderm development 1.000
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3 0.999
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.999
RUVBL2 RuvB-like 2 (E. coli) 0.999
DAXX death-domain associated protein 0.999
RBBP5 retinoblastoma binding protein 5 0.999
INO80 INO80 homolog (S. cerevisiae) 0.999
ARID1A AT rich interactive domain 1A (SWI-like) 0.999
HDAC3 histone deacetylase 3 0.999
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.998
CHD4 chromodomain helicase DNA binding protein 4 0.998
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.998
CBX5 chromobox homolog 5 0.998
NCOR2 nuclear receptor corepressor 2 0.998
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.997
C20orf20 chromosome 20 open reading frame 20 0.997
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.997
TBP TATA box binding protein 0.996
EZH2 enhancer of zeste homolog 2 (Drosophila) 0.996
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.995
SMAD2 SMAD family member 2 0.995
CHD8 chromodomain helicase DNA binding protein 8 0.995
TRIM28 tripartite motif containing 28 0.993
E2F3 E2F transcription factor 3 0.992
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.992
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.992
GSK3B glycogen synthase kinase 3 beta 0.992
SIRT1 sirtuin 1 0.990
CXXC1 CXXC finger protein 1 0.990
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.989
MYST1 MYST histone acetyltransferase 1 0.988
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.988
USP22 ubiquitin specific peptidase 22 0.988
HIST2H3C histone cluster 2, H3c 0.987
DDB1 damage-specific DNA binding protein 1, 127kDa 0.986
KAT5 K(lysine) acetyltransferase 5 0.986
PBRM1 polybromo 1 0.985
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.984
KAT2B K(lysine) acetyltransferase 2B 0.981
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.978
SMAD4 SMAD family member 4 0.977
NCOA1 nuclear receptor coactivator 1 0.976
NCOA6 nuclear receptor coactivator 6 0.975
AR androgen receptor 0.974
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.973
H3F3C H3 histone, family 3C 0.972
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.971
MTA3 metastasis associated 1 family, member 3 0.969
RING1 ring finger protein 1 0.969
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.968
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.967
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.963
E2F1 E2F transcription factor 1 0.958
MTF2 metal response element binding transcription factor 2 0.957
PCNA proliferating cell nuclear antigen 0.957
JUN jun proto-oncogene 0.955
SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 0.954
ASF1A ASF1 anti-silencing function 1 homolog A (S. cerevisiae) 0.953
RBBP7 retinoblastoma binding protein 7 0.952
ATF2 activating transcription factor 2 0.952
RNF20 ring finger protein 20 0.952
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.952
NCOA2 nuclear receptor coactivator 2 0.950
HDGF hepatoma-derived growth factor 0.947
CUL4A cullin 4A 0.944
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.942
BCOR BCL6 corepressor 0.941
MLL2 myeloid/lymphoid or mixed-lineage leukemia 2 0.940
MLL3 myeloid/lymphoid or mixed-lineage leukemia 3 0.940
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.935
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.930
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.927
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Rnf2 ring finger protein 2 1.000
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.000
Arid1a AT rich interactive domain 1A (SWI-like) 1.000
Trp53 transformation related protein 53 1.000
Pou5f1 POU domain, class 5, transcription factor 1 1.000
Rybp RING1 and YY1 binding protein 0.999
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.999
Wdr5 WD repeat domain 5 0.998
Trrap transformation/transcription domain-associated protein 0.991
Crebbp CREB binding protein 0.990
Kdm2b lysine (K)-specific demethylase 2B 0.988
Cdk1 cyclin-dependent kinase 1 0.987
Hdac1 histone deacetylase 1 0.986
Mll1 myeloid/lymphoid or mixed-lineage leukemia 1 0.982
Kdm1a lysine (K)-specific demethylase 1A 0.978
Nanog Nanog homeobox 0.975
Kat2a K(lysine) acetyltransferase 2A 0.973
Mga MAX gene associated 0.972
Pten phosphatase and tensin homolog 0.972
Ep300 E1A binding protein p300 0.970
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.970
Rbbp4 retinoblastoma binding protein 4 0.968
Esr1 estrogen receptor 1 (alpha) 0.967
Sin3a transcriptional regulator, SIN3A (yeast) 0.966
Polr2a polymerase (RNA) II (DNA directed) polypeptide A 0.952
Mta1 metastasis associated 1 0.951
Tcf3 transcription factor 3 0.947
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.945
Rb1 retinoblastoma 1 0.943
Arid1b AT rich interactive domain 1B (SWI-like) 0.941
Pitx2 paired-like homeodomain transcription factor 2 0.939
Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.938
H3f3a H3 histone, family 3A 0.933
Per2 period homolog 2 (Drosophila) 0.921
Sall4 sal-like 4 (Drosophila) 0.920
Trim28 tripartite motif-containing 28 0.919
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.907
Tcfcp2l1 transcription factor CP2-like 1 0.903
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.893
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.890
Runx1 runt related transcription factor 1 0.886
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.884
Mdm4 transformed mouse 3T3 cell double minute 4 0.879
Ctcf CCCTC-binding factor 0.872
Jarid2 jumonji, AT rich interactive domain 2 0.863
Ncor1 nuclear receptor co-repressor 1 0.862
Dnmt3a DNA methyltransferase 3A 0.858
Arid4b AT rich interactive domain 4B (RBP1-like) 0.852
Mef2d myocyte enhancer factor 2D 0.846
Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.840
Dmap1 DNA methyltransferase 1-associated protein 1 0.838
Ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.830
Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.827
Gata4 GATA binding protein 4 0.826
Brd4 bromodomain containing 4 0.818
Neurod1 neurogenic differentiation 1 0.818
Jun Jun oncogene 0.812
Tal1 T-cell acute lymphocytic leukemia 1 0.810
Brca1 breast cancer 1 0.806
Pcgf2 polycomb group ring finger 2 0.796
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.795
Arid2 AT rich interactive domain 2 (ARID, RFX-like) 0.793
Nacc1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.774
Hnrnpu heterogeneous nuclear ribonucleoprotein U 0.771
Dnmt3b DNA methyltransferase 3B 0.766
Nono non-POU-domain-containing, octamer binding protein 0.765
Cry2 cryptochrome 2 (photolyase-like) 0.761
Chd4 chromodomain helicase DNA binding protein 4 0.760
Lep leptin 0.758
Cdc73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.754
Cbx2 chromobox homolog 2 (Drosophila Pc class) 0.740
Cdk4 cyclin-dependent kinase 4 0.739
Brd2 bromodomain containing 2 0.730
Otx2 orthodenticle homolog 2 (Drosophila) 0.713
Bcor BCL6 interacting corepressor 0.696
Acin1 apoptotic chromatin condensation inducer 1 0.693
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.685
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.682
Creb1 cAMP responsive element binding protein 1 0.671
Ep400 E1A binding protein p400 0.665
Hand1 heart and neural crest derivatives expressed transcript 1 0.638
Eed embryonic ectoderm development 0.633
Trp63 transformation related protein 63 0.633
Zeb1 zinc finger E-box binding homeobox 1 0.627
Nr0b1 nuclear receptor subfamily 0, group B, member 1 0.627
Mta2 metastasis-associated gene family, member 2 0.626
Rbbp7 retinoblastoma binding protein 7 0.623
Bmi1 Bmi1 polycomb ring finger oncogene 0.622
Cbx3 chromobox homolog 3 (Drosophila HP1 gamma) 0.621
Ewsr1 Ewing sarcoma breakpoint region 1 0.621
Hist1h3g histone cluster 1, H3g 0.618
Phc1 polyhomeotic-like 1 (Drosophila) 0.616
Skil SKI-like 0.614
Gata1 GATA binding protein 1 0.614
Brd1 bromodomain containing 1 0.613
Smc3 structural maintenace of chromosomes 3 0.596
Gli3 GLI-Kruppel family member GLI3 0.595
Terf1 telomeric repeat binding factor 1 0.590
Mbd3 methyl-CpG binding domain protein 3 0.586
Cbx8 chromobox homolog 8 (Drosophila Pc class) 0.580
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Casp2 caspase 2 0.158
Phf12 PHD finger protein 12 0.125
Mcm6 minichromosome maintenance complex component 6 0.108
Map2k7 mitogen activated protein kinase kinase 7 0.104
Top2a topoisomerase (DNA) II alpha 0.095
Trim28 tripartite motif-containing 28 0.073
LOC688211 hypothetical protein LOC688211 0.066
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.064
Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.063
Mcm7 minichromosome maintenance complex component 7 0.059
Snrpb small nuclear ribonucleoprotein polypeptides B and B1 0.057
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.053
Srrm2 serine/arginine repetitive matrix 2 0.052
Myst3 MYST histone acetyltransferase (monocytic leukemia) 3 0.048
Parp1 poly (ADP-ribose) polymerase 1 0.046
Srrm1 serine/arginine repetitive matrix 1 0.045
Actb actin, beta 0.045
Cdc2l6 cell division cycle 2-like 6 (CDK8-like) 0.045
Rnf166 ring finger protein 166 0.044
Acin1 apoptotic chromatin condensation inducer 1 0.043
Usp7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.042
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.042
Brd4 bromodomain containing 4 0.040
Pcna proliferating cell nuclear antigen 0.040
Dcaf15 DDB1 and CUL4 associated factor 15 0.039
MGC112830 similar to transcription factor 0.039
Mll4 myeloid/lymphoid or mixed-lineage leukemia 4 0.038
Falz fetal Alzheimer antigen 0.037
Rere arginine-glutamic acid dipeptide (RE) repeats 0.036
Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) 0.036
Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.036
Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.035
Gigyf1 GRB10 interacting GYF protein 1 0.035
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.034
Med1 mediator complex subunit 1 0.034
Phf2 PHD finger protein 2 0.032
Ehmt1 euchromatic histone-lysine N-methyltransferase 1 0.032
Rnf138 ring finger protein 138 0.031
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.030
Hnrnpl heterogeneous nuclear ribonucleoprotein L 0.030
LOC687711 similar to small nuclear ribonucleoprotein D3 0.030
Klf9 Kruppel-like factor 9 0.029
Rai1 retinoic acid induced 1 0.029
Hnrnpu heterogeneous nuclear ribonucleoprotein U 0.029
Numa1 nuclear mitotic apparatus protein 1 0.028
Kat5 K(lysine) acetyltransferase 5 0.027
Vezf1 vascular endothelial zinc finger 1 0.027
Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.026
Zfp278 zinc finger protein 278 0.026
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.025
Cops7b COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) 0.024
Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform 0.023
Eif3b eukaryotic translation initiation factor 3, subunit B 0.023
Gtf3c1 general transcription factor IIIC, polypeptide 1, alpha 0.023
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.023
Fam193a family with sequence similarity 193, member A 0.023
Ube2c ubiquitin-conjugating enzyme E2C 0.022
Nxf1 nuclear RNA export factor 1 0.022
Wdr26 WD repeat domain 26 0.022
Fen1 flap structure-specific endonuclease 1 0.022
Snrpa small nuclear ribonucleoprotein polypeptide A 0.022
Mepce methylphosphate capping enzyme 0.021
Klf2 Kruppel-like factor 2 (lung) 0.021
Wbp11 WW domain binding protein 11 0.021
Dnal4 dynein, axonemal, light chain 4 0.021
Tcfe2a transcription factor E2a 0.021
Rad21 RAD21 homolog (S. pombe) 0.020
Whsc2 Wolf-Hirschhorn syndrome candidate 2 (human) 0.020
Odc1 ornithine decarboxylase 1 0.020
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.020
Tuba1c tubulin, alpha 1C 0.020
Chd4 chromodomain helicase DNA binding protein 4 0.020
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.020
Cdkn3 cyclin-dependent kinase inhibitor 3 0.019
Axin1 axin 1 0.019
Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 0.019
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.019
Ubr4 ubiquitin protein ligase E3 component n-recognin 4 0.019
H2afx H2A histone family, member X 0.019
Mprip myosin phosphatase Rho interacting protein 0.019
Aurka aurora kinase A 0.019
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.019
Brd3 bromodomain containing 3 0.018
Calcoco1 calcium binding and coiled coil domain 1 0.018
Ncor1 nuclear receptor co-repressor 1 0.018
Stag1 stromal antigen 1 0.018
Ldb1 LIM domain binding 1 0.018
Mak10 MAK10 homolog, amino-acid N-acetyltransferase subunit, (S. cerevisiae) 0.018
Dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.018
Foxm1 forkhead box M1 0.017
Col4a3bp collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.017
Mcm4 minichromosome maintenance complex component 4 0.017
Mapk14 mitogen activated protein kinase 14 0.017
Myo1b myosin Ib 0.017
Brms1l breast cancer metastasis-suppressor 1-like 0.017
Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.017
Sfrs4 splicing factor, arginine/serine-rich 4 0.017
Cpsf7 cleavage and polyadenylation specific factor 7 0.017
Nfat5 nuclear factor of activated T-cells 5 0.017
Stip1 stress-induced phosphoprotein 1 0.016