The network for 'carboxylic acid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

carboxylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ARG5,6 Arg5,6p 0.936
ARG1 Arg1p 0.874
THR4 Thr4p 0.822
TRP3 Trp3p 0.819
FAS1 Fas1p 0.804
ARO8 Aro8p 0.803
TRP2 Trp2p 0.790
ASN1 Asn1p 0.765
BAT1 Bat1p 0.737
ARO1 Aro1p 0.734
MET13 Met13p 0.715
ARO2 Aro2p 0.708
ACC1 Acc1p 0.685
MET6 Met6p 0.678
SER1 Ser1p 0.671
ARG2 Arg2p 0.657
ILV6 Ilv6p 0.645
ARG4 Arg4p 0.639
LEU9 Leu9p 0.633
ILV3 Ilv3p 0.614
HOM3 Hom3p 0.612
MAE1 Mae1p 0.607
LYS1 Lys1p 0.579
MET14 Met14p 0.556
GDH1 Gdh1p 0.535
LYS21 Lys21p 0.522
MET3 Met3p 0.522
LYS2 Lys2p 0.484
GLN3 Gln3p 0.439
MET16 Met16p 0.436
CYS3 Cys3p 0.435
ACS2 Acs2p 0.415
OAC1 Oac1p 0.409
HIS3 His3p 0.407
BIO3 Bio3p 0.404
ADE4 Ade4p 0.401
HIS5 His5p 0.384
PRO2 Pro2p 0.380
ILV2 Ilv2p 0.374
HIS7 His7p 0.365
TRP4 Trp4p 0.362
LEU1 Leu1p 0.358
SNT1 Snt1p 0.357
SAM1 Sam1p 0.353
ARG7 Arg7p 0.350
ALD5 Ald5p 0.350
IDP1 Idp1p 0.342
MCT1 Mct1p 0.342
THR1 Thr1p 0.337
YMC1 Ymc1p 0.336
SKP2 Skp2p 0.334
GSF2 Gsf2p 0.331
LEU4 Leu4p 0.328
LYS20 Lys20p 0.326
GGC1 Ggc1p 0.325
ILV1 Ilv1p 0.320
UBP14 Ubp14p 0.319
MIG2 Mig2p 0.308
HOM2 Hom2p 0.307
RPN4 Rpn4p 0.301
ARO4 Aro4p 0.300
SPE3 Spe3p 0.299
ZWF1 Zwf1p 0.298
MET10 Met10p 0.295
HAL5 Hal5p 0.294
ADE3 Ade3p 0.289
GCS1 Gcs1p 0.288
YGR210C hypothetical protein 0.281
HIS4 His4p 0.275
ODC2 Odc2p 0.274
NUP100 Nup100p 0.274
ETR1 Etr1p 0.272
KRS1 Krs1p 0.268
MET17 Met17p 0.267
MMP1 Mmp1p 0.263
YLR179C hypothetical protein 0.259
YLR057W hypothetical protein 0.258
URA2 Ura2p 0.252
DUG1 Dug1p 0.238
FSF1 Fsf1p 0.237
SHM2 Shm2p 0.234
YKR015C hypothetical protein 0.234
CKI1 Cki1p 0.231
ARO3 Aro3p 0.231
PHO86 Pho86p 0.227
FMP40 Fmp40p 0.225
OAF3 Oaf3p 0.223
GCD7 Gcd7p 0.222
DNM1 Dnm1p 0.221
TAL1 Tal1p 0.214
DCS2 Dcs2p 0.211
NPL3 Npl3p 0.208
SRV2 Srv2p 0.208
VPS75 Vps75p 0.205
ARG8 Arg8p 0.204
EAP1 Eap1p 0.204
NIF3 Nif3p 0.202
YDR061W hypothetical protein 0.201
CYB2 Cyb2p 0.200
YFR006W hypothetical protein 0.195
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
pmt-1 Protein PMT-1 0.371
hpo-8 Protein HPO-8 0.324
metr-1 Protein METR-1 0.321
fat-6 Protein FAT-6 0.262
egl-13 Protein EGL-13 0.188
sams-3 Protein SAMS-3 0.183
mtrr-1 Protein MTRR-1 0.167
brp-1 Protein BRP-1 0.153
cat-1 Protein CAT-1 0.139
elo-2 Protein ELO-2 0.134
fat-2 Protein FAT-2 0.127
fat-4 Protein FAT-4 0.124
T25B9.9 Protein T25B9.9 0.109
F22F7.1 Protein F22F7.1 0.103
best-13 Protein BEST-13 0.096
mboa-3 Protein MBOA-3 0.095
elo-5 Protein ELO-5 0.089
nit-1 Protein NIT-1 0.087
toc-1 Protein TOC-1 0.076
elo-1 Protein ELO-1 0.074
pmt-2 Protein PMT-2 0.065
hgo-1 Protein HGO-1 0.063
unc-9 Protein UNC-9 0.062
unc-42 Protein UNC-42 0.051
pyk-2 Protein PYK-2 0.049
M03B6.2 Protein M03B6.2 0.049
mce-1 Protein MCE-1 0.048
hel-1 Protein HEL-1 0.048
C44C1.5 Protein C44C1.5 0.045
ceeh-2 Protein CEEH-2 0.045
dhp-1 Protein DHP-1 0.045
gpd-3 Protein GPD-3 0.045
R05D3.9 Protein R05D3.9 0.044
unc-62 Protein UNC-62 0.044
fat-3 Protein FAT-3 0.044
ugt-58 Protein UGT-58 0.044
nspa-8 Protein NSPA-8 0.043
pha-4 Protein PHA-4 0.043
sptl-1 Protein SPTL-1 0.042
pyc-1 Protein PYC-1 0.041
cpi-2 Protein CPI-2 0.041
msra-1 Protein MSRA-1 0.041
cth-2 Protein CTH-2 0.040
F53F10.2 Protein F53F10.2 0.040
cept-1 Protein CEPT-1 0.040
pod-2 Protein POD-2 0.039
CELE_Y37A1B.5 Protein Y37A1B.5 0.039
mel-32 Protein MEL-32 0.039
crls-1 Protein CRLS-1 0.039
ZK484.1 Protein ZK484.1 0.039
cytb-5.1 Protein CYTB-5.1 0.037
eya-1 Protein EYA-1 0.036
hpd-1 Protein HPD-1 0.035
nspa-9 Protein NSPA-9 0.035
sptl-2 Protein SPTL-2 0.035
Y76A2B.5 Protein Y76A2B.5 0.035
mmaa-1 Protein MMAA-1 0.034
mthf-1 Protein MTHF-1 0.032
cts-1 Protein CTS-1 0.032
sur-5 Protein SUR-5 0.031
sulp-8 Protein SULP-8 0.031
ant-1.1 Protein ANT-1.1 0.030
par-5 Protein PAR-5 0.029
zip-7 Protein ZIP-7 0.029
lin-66 Protein LIN-66 0.029
T28D9.3 Protein T28D9.3 0.029
spp-10 Protein SPP-10 0.029
sptl-3 Protein SPTL-3 0.029
K07B1.4 Protein K07B1.4 0.028
CELE_Y67A10A.9 Protein Y67A10A.9 0.027
K07E3.4 Protein K07E3.4 0.026
CELE_R02D3.1 Protein R02D3.1 0.026
R08E5.3 Protein R08E5.3 0.026
R07E3.4 Protein R07E3.4 0.026
CELE_R04B5.5 Protein R04B5.5 0.025
ahcy-1 Protein AHCY-1 0.025
E01A2.5 Protein E01A2.5 0.025
ztf-30 Protein ZTF-30 0.024
CELE_ZK228.3 Protein ZK228.3 0.024
acl-6 Protein ACL-6 0.023
unc-75 Protein UNC-75 0.023
pes-9 Protein PES-9 0.023
acs-17 Protein ACS-17 0.023
mml-1 Protein MML-1 0.022
ckc-1 Protein CKC-1 0.022
uda-1 Protein UDA-1 0.022
T26C12.1 Protein T26C12.1 0.022
C44B7.10 Protein C44B7.10 0.022
CELE_F44D12.9 Protein F44D12.9 0.022
ceh-30 Protein CEH-30 0.022
C34F6.10 Protein C34F6.10 0.021
skr-19 Protein SKR-19 0.021
ida-1 Protein IDA-1 0.021
CELE_Y53C10A.5 Protein Y53C10A.5 0.021
cyp-43A1 Protein CYP-43A1 0.021
ctbp-1 Protein CTBP-1 0.020
ethe-1 Protein ETHE-1 0.020
got-2.2 Protein GOT-2.2 0.020
cpin-1 Protein CPIN-1 0.020
aak-2 Protein AAK-2 0.019
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gpia glucose phosphate isomerase a 0.665
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.169
axin1 axin 1 0.111
ivd isovaleryl Coenzyme A dehydrogenase 0.094
acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.092
cyp51 cytochrome P450, family 51 0.085
fads2 fatty acid desaturase 2 0.070
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.070
atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide 0.065
cx27.5 connexin 27.5 0.061
wls wntless homolog (Drosophila) 0.060
esr2b estrogen receptor 2b 0.052
snx1 sorting nexin 1 0.051
zgc:66382 zgc:66382 0.051
slc4a2b solute carrier family 4, anion exchanger, member 2b 0.050
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.049
aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.048
hsd17b12b hydroxysteroid (17-beta) dehydrogenase 12b 0.046
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.046
fetub fetuin B 0.044
hmx2 H6 family homeobox 2 0.043
zgc:92360 zgc:92360 0.042
ocrl oculocerebrorenal syndrome of Lowe 0.040
tpi1b triosephosphate isomerase 1b 0.039
apoa4 apolipoprotein A-IV 0.038
pawrl PRKC, apoptosis, WT1, regulator like 0.037
mat1a methionine adenosyltransferase I, alpha 0.036
fabp10a fatty acid binding protein 10a, liver basic 0.034
esr1 estrogen receptor 1 0.033
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.033
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.032
ptgs2a prostaglandin-endoperoxide synthase 2a 0.031
ar androgen receptor 0.031
cpt2 carnitine palmitoyltransferase II 0.030
ptgesl prostaglandin E synthase 2-like 0.028
cnp 2',3'-cyclic nucleotide 3' phosphodiesterase 0.028
gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.027
pomt1 protein-O-mannosyltransferase 1 0.026
kiss1 KiSS-1 metastasis-suppressor 0.026
cyp1b1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.026
dio2 deiodinase, iodothyronine, type II 0.026
olig2 oligodendrocyte lineage transcription factor 2 0.025
acadl acyl-Coenzyme A dehydrogenase, long chain 0.025
hnf1ba HNF1 homeobox Ba 0.024
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.024
abcd3a ATP-binding cassette, sub-family D (ALD), member 3a 0.024
gclm glutamate-cysteine ligase, modifier subunit 0.023
tk2 thymidine kinase 2, mitochondrial 0.023
rln3a relaxin 3a 0.022
plp1b proteolipid protein 1b 0.022
cx30.3 connexin 30.3 0.022
nos1 nitric oxide synthase 1 (neuronal) 0.022
gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.022
mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 0.021
hmx4 H6 family homeobox 4 0.021
aldoca aldolase C, fructose-bisphosphate, a 0.021
rrm2b ribonucleotide reductase M2 b 0.021
pgam1b phosphoglycerate mutase 1b 0.021
ddc dopa decarboxylase 0.020
rxrba retinoid x receptor, beta a 0.020
slc8a1b solute carrier family 8 (sodium/calcium exchanger), member 1b 0.020
paqr7b progestin and adipoQ receptor family member VII, b 0.020
cpa2 carboxypeptidase A2 (pancreatic) 0.020
sh3gl2 SH3-domain GRB2-like 2 0.020
tp53 tumor protein p53 0.020
mbnl1 muscleblind-like (Drosophila) 0.019
ndufa4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 0.019
zgc:101565 zgc:101565 0.019
her7 hairy and enhancer of split related-7 0.019
ucp1 uncoupling protein 1 0.019
uox urate oxidase 0.019
zgc:123180 zgc:123180 0.019
zgc:64076 zgc:64076 0.018
hmgb3b high-mobility group box 3b 0.018
hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.018
acsl4a acyl-CoA synthetase long-chain family member 4a 0.018
sod2 superoxide dismutase 2, mitochondrial 0.018
sgk1 serum/glucocorticoid regulated kinase 1 0.018
ptgds prostaglandin D2 synthase 0.018
chd7 chromodomain helicase DNA binding protein 7 0.018
LOC100002342 carboxypeptidase A6-like 0.018
tpma alpha-tropomyosin 0.018
vangl2 vang-like 2 (van gogh, Drosophila) 0.018
sec23a Sec23 homolog A (S. cerevisiae) 0.018
ascl1a achaete-scute complex-like 1a (Drosophila) 0.017
igfbp2a insulin-like growth factor binding protein 2a 0.017
cntn1b contactin 1b 0.017
adipor1b adiponectin receptor 1b 0.017
zgc:64133 zgc:64133 0.017
si:ch211-93f2.1 si:ch211-93f2.1 0.017
ncam2 neural cell adhesion molecule 2 0.017
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.017
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.017
cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 0.017
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.016
adh8a alcohol dehydrogenase 8a 0.016
agxta alanine-glyoxylate aminotransferase a 0.016
ckbb creatine kinase, brain b 0.016
degs1 degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) 0.016
hkdc1 hexokinase domain containing 1 0.015
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
CG30008 CG30008 gene product from transcript CG30008-RA 0.362
CG16904 CG16904 gene product from transcript CG16904-RA 0.285
CG18609 CG18609 gene product from transcript CG18609-RA 0.202
CG11147 CG11147 gene product from transcript CG11147-RA 0.199
CG6660 CG6660 gene product from transcript CG6660-RA 0.144
Got2 Glutamate oxaloacetate transaminase 2 0.100
CG4020 CG4020 gene product from transcript CG4020-RA 0.091
sea scheggia 0.085
CG7910 CG7910 gene product from transcript CG7910-RA 0.084
CG3523 CG3523 gene product from transcript CG3523-RA 0.079
eloF elongase F 0.072
CG11198 CG11198 gene product from transcript CG11198-RB 0.071
Sc2 CG10849 gene product from transcript CG10849-RA 0.065
Yp2 Yolk protein 2 0.064
Fad2 CG7923 gene product from transcript CG7923-RA 0.055
Yp3 Yolk protein 3 0.054
Pgd Phosphogluconate dehydrogenase 0.052
CG9458 CG9458 gene product from transcript CG9458-RA 0.048
CG9459 CG9459 gene product from transcript CG9459-RA 0.038
Eno Enolase 0.037
CG6455 CG6455 gene product from transcript CG6455-RC 0.035
CG8036 CG8036 gene product from transcript CG8036-RB 0.035
CG1907 CG1907 gene product from transcript CG1907-RA 0.034
Fdh Formaldehyde dehydrogenase 0.034
CG10863 CG10863 gene product from transcript CG10863-RA 0.034
CG14506 CG14506 gene product from transcript CG14506-RA 0.034
CG14820 CG14820 gene product from transcript CG14820-RA 0.033
desat1 CG5887 gene product from transcript CG5887-RA 0.033
CG13091 CG13091 gene product from transcript CG13091-RA 0.032
yip2 yippee interacting protein 2 0.032
CG6543 CG6543 gene product from transcript CG6543-RA 0.031
CG7920 CG7920 gene product from transcript CG7920-RA 0.030
CG1443 CG1443 gene product from transcript CG1443-RA 0.029
CG33110 CG33110 gene product from transcript CG33110-RA 0.027
FK506-bp2 FK506-binding protein 2 0.026
CG8630 CG8630 gene product from transcript CG8630-RA 0.024
regucalcin CG1803 gene product from transcript CG1803-RA 0.024
CG5362 CG5362 gene product from transcript CG5362-RA 0.023
CG14196 CG14196 gene product from transcript CG14196-RA 0.023
Myo31DF Myosin 31DF 0.022
AcCoAS Acetyl Coenzyme A synthase 0.021
emp epithelial membrane protein 0.021
CG17560 CG17560 gene product from transcript CG17560-RA 0.020
CG11255 CG11255 gene product from transcript CG11255-RA 0.020
Nlp Nucleoplasmin 0.019
CG9990 CG9990 gene product from transcript CG9990-RA 0.019
CG2254 CG2254 gene product from transcript CG2254-RA 0.018
Aldh-III Aldehyde dehydrogenase type III 0.018
Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2 0.017
CG30427 CG30427 gene product from transcript CG30427-RC 0.017
CG16704 CG16704 gene product from transcript CG16704-RA 0.017
betaTry betaTrypsin 0.016
CG9106 CG9106 gene product from transcript CG9106-RA 0.016
CG6283 CG6283 gene product from transcript CG6283-RA 0.016
CG12262 CG12262 gene product from transcript CG12262-RA 0.016
LvpH Larval visceral protein H 0.016
laza lazaro 0.015
CG12374 CG12374 gene product from transcript CG12374-RA 0.015
CG17374 CG17374 gene product from transcript CG17374-RB 0.015
Cyp4g1 Cytochrome P450-4g1 0.015
Idh Isocitrate dehydrogenase 0.015
n-syb n-synaptobrevin 0.014
nudC CG9710 gene product from transcript CG9710-RA 0.014
CG18745 CG18745 gene product from transcript CG18745-RA 0.014
CG1516 CG1516 gene product from transcript CG1516-RP 0.014
CG10639 CG10639 gene product from transcript CG10639-RA 0.014
cl clot 0.014
CG12990 CG12990 gene product from transcript CG12990-RA 0.014
dia diaphanous 0.013
CG6415 CG6415 gene product from transcript CG6415-RA 0.013
CheB93a Chemosensory protein B 93a 0.013
Sodh-1 Sorbitol dehydrogenase 1 0.013
CG4666 CG4666 gene product from transcript CG4666-RA 0.013
AnnX Annexin X 0.013
CG14119 CG14119 gene product from transcript CG14119-RA 0.013
CG15531 CG15531 gene product from transcript CG15531-RB 0.013
Vm26Ab Vitelline membrane 26Ab 0.012
CG2852 CG2852 gene product from transcript CG2852-RA 0.012
CG8128 CG8128 gene product from transcript CG8128-RA 0.012
CG3513 CG3513 gene product from transcript CG3513-RA 0.012
CG4365 CG4365 gene product from transcript CG4365-RB 0.012
CG34120 CG34120 gene product from transcript CG34120-RC 0.012
janA janus A 0.012
CG11327 CG11327 gene product from transcript CG11327-RA 0.012
CG8446 CG8446 gene product from transcript CG8446-RC 0.012
PHGPx CG12013 gene product from transcript CG12013-RC 0.012
stumps CG31317 gene product from transcript CG31317-RC 0.011
CG2765 CG2765 gene product from transcript CG2765-RE 0.011
Yp1 Yolk protein 1 0.011
Cpr100A Cuticular protein 100A 0.011
ade5 CG3989 gene product from transcript CG3989-RA 0.011
CG3918 CG3918 gene product from transcript CG3918-RA 0.011
Adh Alcohol dehydrogenase 0.011
Cyp1 Cyclophilin 1 0.011
nec necrotic 0.011
alphaTry alphaTrypsin 0.011
Jon65Aiv Jonah 65Aiv 0.011
Zw Zwischenferment 0.011
Hn Henna 0.011
yellow-f2 CG8063 gene product from transcript CG8063-RA 0.011
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SC4MOL sterol-C4-methyl oxidase-like 0.994
FGF1 fibroblast growth factor 1 (acidic) 0.968
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.951
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.950
GGT1 gamma-glutamyltransferase 1 0.937
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.936
FADS1 fatty acid desaturase 1 0.934
HNF4A hepatocyte nuclear factor 4, alpha 0.880
DHCR7 7-dehydrocholesterol reductase 0.821
APOE apolipoprotein E 0.807
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.714
GGTLC1 gamma-glutamyltransferase light chain 1 0.652
ALDOB aldolase B, fructose-bisphosphate 0.647
COTL1 coactosin-like 1 (Dictyostelium) 0.605
AARS alanyl-tRNA synthetase 0.574
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.538
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.523
TUBGCP4 tubulin, gamma complex associated protein 4 0.522
ACACA acetyl-CoA carboxylase alpha 0.522
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.504
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.490
ALB albumin 0.489
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.486
FADS2 fatty acid desaturase 2 0.480
RXRA retinoid X receptor, alpha 0.478
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.450
PRDX1 peroxiredoxin 1 0.450
GCLC glutamate-cysteine ligase, catalytic subunit 0.443
ATF5 activating transcription factor 5 0.440
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.395
NCOR2 nuclear receptor corepressor 2 0.393
FGFR2 fibroblast growth factor receptor 2 0.362
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.353
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.343
APOC2 apolipoprotein C-II 0.333
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.328
GCLM glutamate-cysteine ligase, modifier subunit 0.325
HP haptoglobin 0.316
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.276
ZFYVE9 zinc finger, FYVE domain containing 9 0.275
PGK1 phosphoglycerate kinase 1 0.272
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.265
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.264
FABP1 fatty acid binding protein 1, liver 0.254
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 0.252
HPD 4-hydroxyphenylpyruvate dioxygenase 0.247
TTLL12 tubulin tyrosine ligase-like family, member 12 0.225
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.215
TST thiosulfate sulfurtransferase (rhodanese) 0.214
SOD1 superoxide dismutase 1, soluble 0.209
ISOC2 isochorismatase domain containing 2 0.209
OTC ornithine carbamoyltransferase 0.199
RAB10 RAB10, member RAS oncogene family 0.197
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.194
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.188
GGT2 gamma-glutamyltransferase 2 0.188
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.187
CRAT carnitine O-acetyltransferase 0.187
ESR1 estrogen receptor 1 0.187
NBN nibrin 0.186
APOA1 apolipoprotein A-I 0.180
RARA retinoic acid receptor, alpha 0.179
CA5A carbonic anhydrase VA, mitochondrial 0.179
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.178
HR hairless homolog (mouse) 0.177
MAT1A methionine adenosyltransferase I, alpha 0.177
SQLE squalene epoxidase 0.172
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 0.171
APCS amyloid P component, serum 0.167
KLB klotho beta 0.166
HMOX2 heme oxygenase (decycling) 2 0.165
PDPK1 3-phosphoinositide dependent protein kinase-1 0.165
ANKRD13A ankyrin repeat domain 13A 0.154
GLYAT glycine-N-acyltransferase 0.154
GLUD1 glutamate dehydrogenase 1 0.153
ICMT isoprenylcysteine carboxyl methyltransferase 0.152
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.152
FGF2 fibroblast growth factor 2 (basic) 0.148
HNF1B HNF1 homeobox B 0.147
SMAD4 SMAD family member 4 0.147
SUFU suppressor of fused homolog (Drosophila) 0.147
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.143
FGF10 fibroblast growth factor 10 0.139
AGXT alanine-glyoxylate aminotransferase 0.138
PPARA peroxisome proliferator-activated receptor alpha 0.136
PAH phenylalanine hydroxylase 0.135
MARS methionyl-tRNA synthetase 0.132
APOC4 apolipoprotein C-IV 0.132
CALCA calcitonin-related polypeptide alpha 0.131
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.131
TALDO1 transaldolase 1 0.130
APOB apolipoprotein B (including Ag(x) antigen) 0.128
PPID peptidylprolyl isomerase D 0.127
DHCR24 24-dehydrocholesterol reductase 0.127
NR1I3 nuclear receptor subfamily 1, group I, member 3 0.127
GLUD2 glutamate dehydrogenase 2 0.126
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.126
APOC1 apolipoprotein C-I 0.125
CXCR4 chemokine (C-X-C motif) receptor 4 0.124
FGFR1 fibroblast growth factor receptor 1 0.123
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Per2 period homolog 2 (Drosophila) 0.846
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.846
Tpi1 triosephosphate isomerase 1 0.824
Kl klotho 0.820
Pax2 paired box gene 2 0.656
Tef thyrotroph embryonic factor 0.609
Cry2 cryptochrome 2 (photolyase-like) 0.598
Rarb retinoic acid receptor, beta 0.573
Ednra endothelin receptor type A 0.569
Fgf8 fibroblast growth factor 8 0.553
F12 coagulation factor XII (Hageman factor) 0.520
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.520
Kit kit oncogene 0.512
Apoe apolipoprotein E 0.487
Acly ATP citrate lyase 0.484
Rxra retinoid X receptor alpha 0.483
Ece1 endothelin converting enzyme 1 0.427
Atf4 activating transcription factor 4 0.421
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.415
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.401
Rarg retinoic acid receptor, gamma 0.390
Trp63 transformation related protein 63 0.373
Slc12a1 solute carrier family 12, member 1 0.349
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.339
Esr1 estrogen receptor 1 (alpha) 0.336
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.324
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.321
Bmp7 bone morphogenetic protein 7 0.317
Scd1 stearoyl-Coenzyme A desaturase 1 0.314
Fgfr1 fibroblast growth factor receptor 1 0.300
Krt72-ps keratin 72, pseudogene 0.292
Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 0.291
Srebf2 sterol regulatory element binding factor 2 0.291
Pax8 paired box gene 8 0.291
Dmgdh dimethylglycine dehydrogenase precursor 0.290
Btrc beta-transducin repeat containing protein 0.282
Ccnd1 cyclin D1 0.278
Smo smoothened homolog (Drosophila) 0.276
Fads2 fatty acid desaturase 2 0.269
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.264
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.254
Per1 period homolog 1 (Drosophila) 0.254
C1qb complement component 1, q subcomponent, beta polypeptide 0.254
Chd7 chromodomain helicase DNA binding protein 7 0.249
Lhx1 LIM homeobox protein 1 0.242
Ahsg alpha-2-HS-glycoprotein 0.242
Afm afamin 0.242
Tcf7 transcription factor 7, T-cell specific 0.240
Igfals insulin-like growth factor binding protein, acid labile subunit 0.236
Prodh2 proline dehydrogenase (oxidase) 2 0.234
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.233
Pcx pyruvate carboxylase 0.231
H2-DMa histocompatibility 2, class II, locus DMa 0.227
Elovl3 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 0.224
Agxt alanine-glyoxylate aminotransferase 0.224
Apoa1 apolipoprotein A-I 0.223
Vdr vitamin D receptor 0.220
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.219
Gnrh1 gonadotropin releasing hormone 1 0.214
Rnf11 ring finger protein 11 0.213
Vegfa vascular endothelial growth factor A 0.210
F13b coagulation factor XIII, beta subunit 0.207
Slc38a3 solute carrier family 38, member 3 0.207
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.202
Sox9 SRY-box containing gene 9 0.202
Akr1c21 aldo-keto reductase family 1, member C21 0.200
Onecut1 one cut domain, family member 1 0.199
Ccl6 chemokine (C-C motif) ligand 6 0.198
Hsd3b4 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 0.196
Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B 0.193
C1qc complement component 1, q subcomponent, C chain 0.192
Ces1c carboxylesterase 1C 0.191
Fads1 fatty acid desaturase 1 0.191
Ctnnb1 catenin (cadherin associated protein), beta 1 0.190
Apoa5 apolipoprotein A-V 0.189
Timd2 T-cell immunoglobulin and mucin domain containing 2 0.189
Rorc RAR-related orphan receptor gamma 0.187
Bmp8b bone morphogenetic protein 8b 0.186
Hgd homogentisate 1, 2-dioxygenase 0.186
Dhcr24 24-dehydrocholesterol reductase 0.186
Ptges prostaglandin E synthase 0.184
F2 coagulation factor II 0.182
Iyd iodotyrosine deiodinase 0.181
Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 0.180
Hes3 hairy and enhancer of split 3 (Drosophila) 0.180
Prlr prolactin receptor 0.179
Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 0.178
Padi1 peptidyl arginine deiminase, type I 0.178
Scd2 stearoyl-Coenzyme A desaturase 2 0.176
Krt32 keratin 32 0.175
Slc6a13 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 0.174
Lipc lipase, hepatic 0.171
Aadat aminoadipate aminotransferase 0.171
Usp2 ubiquitin specific peptidase 2 0.170
Otc ornithine transcarbamylase 0.170
Hand2 heart and neural crest derivatives expressed transcript 2 0.170
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.168
Apoh apolipoprotein H 0.167
Fasn fatty acid synthase 0.166
Proc protein C 0.165
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Fasn fatty acid synthase 0.887
Cd36 CD36 molecule (thrombospondin receptor) 0.650
Dhfr dihydrofolate reductase 0.608
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.584
Dbp D site of albumin promoter (albumin D-box) binding protein 0.576
Aqp9 aquaporin 9 0.565
Fads2 fatty acid desaturase 2 0.561
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.557
Cbs cystathionine beta synthase 0.544
Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M 0.516
Acly ATP citrate lyase 0.487
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.448
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.430
Acads acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain 0.398
Oplah 5-oxoprolinase (ATP-hydrolysing) 0.355
Anxa1 annexin A1 0.335
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.320
Pkm2 pyruvate kinase, muscle 0.313
Tdo2 tryptophan 2,3-dioxygenase 0.298
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.297
Gclc glutamate-cysteine ligase, catalytic subunit 0.279
Tst thiosulfate sulfurtransferase 0.271
Sds serine dehydratase 0.269
Amy2 amylase 2, pancreatic 0.268
Cat catalase 0.267
Prlr prolactin receptor 0.256
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.252
Aqp7 aquaporin 7 0.251
Mettl7b methyltransferase like 7B 0.250
LOC691259 hypothetical protein LOC691259 0.245
Acaca acetyl-coenzyme A carboxylase alpha 0.239
Tspo translocator protein 0.235
Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 0.224
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.212
Fads1 fatty acid desaturase 1 0.203
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.203
Zadh2 zinc binding alcohol dehydrogenase, domain containing 2 0.201
Car5a carbonic anhydrase 5a, mitochondrial 0.186
Gja5 gap junction protein, alpha 5 0.186
Pfkm phosphofructokinase, muscle 0.185
Igfbp1 insulin-like growth factor binding protein 1 0.183
Gsta3 glutathione S-transferase A3 0.180
Fbp1 fructose-1,6-bisphosphatase 1 0.175
Aqp8 aquaporin 8 0.174
Scd1 stearoyl-Coenzyme A desaturase 1 0.170
Fabp4 fatty acid binding protein 4, adipocyte 0.169
Slc26a1 solute carrier family 26 (sulfate transporter), member 1 0.168
Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.166
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.166
Sox13 SRY (sex determining region Y)-box 13 0.164
S100a6 S100 calcium binding protein A6 0.163
Dhdpsl dihydrodipicolinate synthase-like, mitochondrial 0.162
Rdh2 retinol dehydrogenase 2 0.161
Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 0.157
Pla2g2c phospholipase A2, group IIC 0.157
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.153
Bckdha branched chain ketoacid dehydrogenase E1, alpha polypeptide 0.152
Pc pyruvate carboxylase 0.151
Gulo gulonolactone (L-) oxidase 0.150
Acat1 acetyl-coenzyme A acetyltransferase 1 0.150
Dhcr7 7-dehydrocholesterol reductase 0.150
Etfa electron-transfer-flavoprotein, alpha polypeptide 0.149
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.149
Mgst2 microsomal glutathione S-transferase 2 0.142
Etfdh electron-transferring-flavoprotein dehydrogenase 0.140
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.140
Cryab crystallin, alpha B 0.139
Dpys dihydropyrimidinase 0.136
Spp1 secreted phosphoprotein 1 0.135
Anxa5 annexin A5 0.135
S100a11 S100 calcium binding protein A11 (calizzarin) 0.135
Fabp1 fatty acid binding protein 1, liver 0.134
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.132
Acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.132
G6pd glucose-6-phosphate dehydrogenase 0.130
Hrh2 histamine receptor H 2 0.129
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.128
Aldh4a1 aldehyde dehydrogenase 4 family, member A1 0.128
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.126
Glud1 glutamate dehydrogenase 1 0.126
Dcaf11 DDB1 and CUL4 associated factor 11 0.125
Pth2r parathyroid hormone 2 receptor 0.124
Tecr trans-2,3-enoyl-CoA reductase 0.123
Slc9a2 solute carrier family 9 (sodium/hydrogen exchanger), member 2 0.122
Lgals3 lectin, galactoside-binding, soluble, 3 0.122
Cyp51 cytochrome P450, family 51 0.121
Srd5a1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.120
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.119
Gclm glutamate cysteine ligase, modifier subunit 0.119
Fabp5 fatty acid binding protein 5, epidermal 0.118
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.117
Pdk2 pyruvate dehydrogenase kinase, isozyme 2 0.114
Acadvl acyl-Coenzyme A dehydrogenase, very long chain 0.114
Mgst3 microsomal glutathione S-transferase 3 0.113
Aadat aminoadipate aminotransferase 0.113
Acot2 acyl-CoA thioesterase 2 0.113
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.113
Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 0.112
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.111
Acsm3 acyl-CoA synthetase medium-chain family member 3 0.111