The network for 'glucan biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.

Name Description Probability Func Analog Organism
GSY2 Gsy2p 1.000
GSY1 Gsy1p 0.999
GLG2 Glg2p 0.995
GPH1 Gph1p 0.950
PIG2 Pig2p 0.887
GIP2 Gip2p 0.884
UGP1 Ugp1p 0.853
GLG1 Glg1p 0.804
RHO1 Rho1p 0.610
HXK1 Hxk1p 0.609
PSK1 Psk1p 0.582
MKK1 Mkk1p 0.397
GLC7 Glc7p 0.372
PCL10 Pcl10p 0.347
GAC1 Gac1p 0.264
GDB1 Gdb1p 0.263
PHO85 Pho85p 0.207
PCL8 Pcl8p 0.197
MMR1 Mmr1p 0.194
MYO5 Myo5p 0.140
HOC1 Hoc1p 0.139
CAK1 Cak1p 0.119
RDI1 Rdi1p 0.107
KRE6 Kre6p 0.102
YGR071C hypothetical protein 0.098
PKC1 Pkc1p 0.098
EMI2 Emi2p 0.095
ROM2 Rom2p 0.091
RGC1 Rgc1p 0.089
BBC1 Bbc1p 0.070
YNR014W hypothetical protein 0.069
BEM2 Bem2p 0.068
CBK1 Cbk1p 0.067
MPT5 Mpt5p 0.064
YCL042W hypothetical protein 0.062
YGR205W hypothetical protein 0.058
HKR1 Hkr1p 0.052
BDH2 Bdh2p 0.052
PSK2 Psk2p 0.052
RGI1 Rgi1p 0.048
PTP3 Ptp3p 0.046
MER1 Mer1p 0.045
PHO81 Pho81p 0.045
CDC42 Cdc42p 0.043
ACK1 Ack1p 0.043
FMP48 Fmp48p 0.041
MAL32 Mal32p 0.039
YIL151C hypothetical protein 0.037
GLK1 Glk1p 0.037
YGL010W hypothetical protein 0.036
YNL144C hypothetical protein 0.036
LSP1 Lsp1p 0.036
FYV8 Fyv8p 0.035
SGE1 Sge1p 0.035
PCL2 Pcl2p 0.035
DCW1 Dcw1p 0.034
TOS1 Tos1p 0.034
SIA1 Sia1p 0.032
KEL1 Kel1p 0.031
PGM2 Pgm2p 0.031
PGM1 Pgm1p 0.031
GLN1 Gln1p 0.031
SRD1 Srd1p 0.031
TAM41 Tam41p 0.031
RMD5 Rmd5p 0.030
YLR162W hypothetical protein 0.030
YJL181W hypothetical protein 0.030
YLR264C-A hypothetical protein 0.030
MBR1 Mbr1p 0.030
LEU2 Leu2p 0.029
YGL242C hypothetical protein 0.029
EAR1 Ear1p 0.029
PYK2 Pyk2p 0.028
YOL038C-A hypothetical protein 0.028
CCH1 Cch1p 0.027
GIC2 Gic2p 0.027
SUC2 Suc2p 0.027
YLR177W hypothetical protein 0.027
ICS2 Ics2p 0.027
HEM15 Hem15p 0.027
MRK1 Mrk1p 0.026
SSP1 Ssp1p 0.026
SAC7 Sac7p 0.026
CLG1 Clg1p 0.025
HRR25 Hrr25p 0.025
COX5B Cox5bp 0.025
FKS1 Fks1p 0.024
CLN3 Cln3p 0.023
NGL3 Ngl3p 0.023
PNS1 Pns1p 0.023
CHS1 Chs1p 0.023
TRR1 Trr1p 0.023
YNL058C hypothetical protein 0.023
YJR115W hypothetical protein 0.023
SSK1 Ssk1p 0.023
PCL9 Pcl9p 0.023
ICY1 Icy1p 0.023
OCH1 Och1p 0.022
VHS1 Vhs1p 0.022
YNR064C hypothetical protein 0.022
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
CG5362 CG5362 gene product from transcript CG5362-RA 0.227
Thiolase CG4581 gene product from transcript CG4581-RA 0.048
EcR Ecdysone receptor 0.045
Akt1 CG4006 gene product from transcript CG4006-RA 0.039
Pgk Phosphoglycerate kinase 0.038
S6k RPS6-p70-protein kinase 0.033
Thor CG8846 gene product from transcript CG8846-RA 0.029
InR Insulin-like receptor 0.026
Zw Zwischenferment 0.024
Idh Isocitrate dehydrogenase 0.020
Pgi Phosphoglucose isomerase 0.019
foxo forkhead box, sub-group O 0.018
CkIalpha Casein kinase Ialpha 0.016
Got2 Glutamate oxaloacetate transaminase 2 0.016
Gs1 Glutamine synthetase 1 0.015
CycG Cyclin G 0.014
Pgd Phosphogluconate dehydrogenase 0.014
Hcf Host cell factor 0.014
Tpi Triose phosphate isomerase 0.014
dm diminutive 0.013
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.013
Men Malic enzyme 0.012
myoglianin CG1838 gene product from transcript CG1838-RD 0.011
CG6904 CG6904 gene product from transcript CG6904-RC 0.011
PyK Pyruvate kinase 0.011
bsk basket 0.011
Sxl Sex lethal 0.010
Gip GIP-like 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
INSR insulin receptor 1.000
GRB10 growth factor receptor-bound protein 10 0.991
IRS2 insulin receptor substrate 2 0.954
IRS1 insulin receptor substrate 1 0.911
IGF1R insulin-like growth factor 1 receptor 0.888
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.550
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.482
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.415
DCAF7 DDB1 and CUL4 associated factor 7 0.312
NOXA1 NADPH oxidase activator 1 0.256
PRKCZ protein kinase C, zeta 0.252
PRKCB protein kinase C, beta 0.251
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.133
STAT5B signal transducer and activator of transcription 5B 0.131
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.119
IGF2R insulin-like growth factor 2 receptor 0.114
GYS1 glycogen synthase 1 (muscle) 0.109
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.102
SH2B1 SH2B adaptor protein 1 0.074
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.070
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.067
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.063
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.060
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.056
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.052
NCF1 neutrophil cytosolic factor 1 0.044
GYG2 glycogenin 2 0.043
PKM2 pyruvate kinase, muscle 0.041
HIPK2 homeodomain interacting protein kinase 2 0.040
GYG1 glycogenin 1 0.036
RAB6A RAB6A, member RAS oncogene family 0.034
PICK1 protein interacting with PRKCA 1 0.034
LDHA lactate dehydrogenase A 0.033
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.031
SH3RF1 SH3 domain containing ring finger 1 0.030
RAB1A RAB1A, member RAS oncogene family 0.028
BCL2 B-cell CLL/lymphoma 2 0.027
LZTS2 leucine zipper, putative tumor suppressor 2 0.026
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.025
PRKCA protein kinase C, alpha 0.023
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.022
ARF4 ADP-ribosylation factor 4 0.022
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.021
CCL14 chemokine (C-C motif) ligand 14 0.021
ALDOA aldolase A, fructose-bisphosphate 0.021
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.021
FAF1 Fas (TNFRSF6) associated factor 1 0.021
OSBP oxysterol binding protein 0.021
KAT2B K(lysine) acetyltransferase 2B 0.020
DCTN1 dynactin 1 0.020
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.019
SYK spleen tyrosine kinase 0.019
GCKR glucokinase (hexokinase 4) regulator 0.019
SEC24A SEC24 family, member A (S. cerevisiae) 0.019
PILRA paired immunoglobin-like type 2 receptor alpha 0.018
SCP2 sterol carrier protein 2 0.018
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 0.018
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.017
S100A2 S100 calcium binding protein A2 0.017
TSC22D1 TSC22 domain family, member 1 0.017
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.016
RAB14 RAB14, member RAS oncogene family 0.015
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.015
GRB14 growth factor receptor-bound protein 14 0.015
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.015
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.015
RAB8A RAB8A, member RAS oncogene family 0.014
SESN2 sestrin 2 0.014
CSK c-src tyrosine kinase 0.014
PDPK1 3-phosphoinositide dependent protein kinase-1 0.014
RPL11 ribosomal protein L11 0.013
GYS2 glycogen synthase 2 (liver) 0.013
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 0.013
PPID peptidylprolyl isomerase D 0.013
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.013
GBAS glioblastoma amplified sequence 0.012
CCND1 cyclin D1 0.012
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.012
CCDC115 coiled-coil domain containing 115 0.012
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.011
SPRED1 sprouty-related, EVH1 domain containing 1 0.011
SETDB1 SET domain, bifurcated 1 0.011
BAD BCL2-associated agonist of cell death 0.011
VHL von Hippel-Lindau tumor suppressor 0.011
BCKDK branched chain ketoacid dehydrogenase kinase 0.011
FOXO1 forkhead box O1 0.011
TRIM9 tripartite motif containing 9 0.011
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.011
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.011
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.011
CYBA cytochrome b-245, alpha polypeptide 0.010
CUX1 cut-like homeobox 1 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Insr insulin receptor 0.975
Rarg retinoic acid receptor, gamma 0.808
Irs2 insulin receptor substrate 2 0.743
Cry2 cryptochrome 2 (photolyase-like) 0.691
Per1 period homolog 1 (Drosophila) 0.605
Lepr leptin receptor 0.554
Ghr growth hormone receptor 0.506
Grb10 growth factor receptor bound protein 10 0.390
Igf1r insulin-like growth factor I receptor 0.369
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.303
Tef thyrotroph embryonic factor 0.295
Rara retinoic acid receptor, alpha 0.260
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.259
Per2 period homolog 2 (Drosophila) 0.257
Pim3 proviral integration site 3 0.142
Dbp D site albumin promoter binding protein 0.136
Rxra retinoid X receptor alpha 0.099
Akt1 thymoma viral proto-oncogene 1 0.088
Igf2r insulin-like growth factor 2 receptor 0.082
Pax2 paired box gene 2 0.077
Ednra endothelin receptor type A 0.076
Usp2 ubiquitin specific peptidase 2 0.074
Tenc1 tensin like C1 domain-containing phosphatase 0.072
Klf9 Kruppel-like factor 9 0.069
Pim2 proviral integration site 2 0.061
Skp1a S-phase kinase-associated protein 1A 0.060
Pnpla2 patatin-like phospholipase domain containing 2 0.059
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.057
Rarb retinoic acid receptor, beta 0.054
Thra thyroid hormone receptor alpha 0.052
Igf2 insulin-like growth factor 2 0.048
Akt2 thymoma viral proto-oncogene 2 0.046
Lhx3 LIM homeobox protein 3 0.045
Ins2 insulin II 0.044
Irs1 insulin receptor substrate 1 0.040
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.038
Csnk1e casein kinase 1, epsilon 0.037
Btrc beta-transducin repeat containing protein 0.036
Hoxa3 homeobox A3 0.033
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.033
Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) 0.030
Ece1 endothelin converting enzyme 1 0.029
Bmper BMP-binding endothelial regulator 0.029
Lipe lipase, hormone sensitive 0.028
Hoxb3 homeobox B3 0.025
Thrb thyroid hormone receptor beta 0.025
Capn1 calpain 1 0.023
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.022
Tpo thyroid peroxidase 0.021
Sim1 single-minded homolog 1 (Drosophila) 0.021
Eya1 eyes absent 1 homolog (Drosophila) 0.021
Lpin1 lipin 1 0.021
Pax8 paired box gene 8 0.020
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.020
Rps2 ribosomal protein S2 0.019
Rps3 ribosomal protein S3 0.019
Vapa vesicle-associated membrane protein, associated protein A 0.019
Nfic nuclear factor I/C 0.018
Chrd chordin 0.018
Ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.018
Per3 period homolog 3 (Drosophila) 0.018
Cav1 caveolin 1, caveolae protein 0.017
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.017
Ar androgen receptor 0.017
Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.017
Clock circadian locomotor output cycles kaput 0.017
Pim1 proviral integration site 1 0.016
Itga1 integrin alpha 1 0.016
Car11 carbonic anhydrase 11 0.016
Stat5a signal transducer and activator of transcription 5A 0.016
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.015
Tff1 trefoil factor 1 0.015
Pparg peroxisome proliferator activated receptor gamma 0.015
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.015
Rora RAR-related orphan receptor alpha 0.015
Tgfbr3 transforming growth factor, beta receptor III 0.014
Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 0.014
Fgfr1 fibroblast growth factor receptor 1 0.014
2310035K24Rik RIKEN cDNA 2310035K24 gene 0.014
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.014
Inppl1 inositol polyphosphate phosphatase-like 1 0.014
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.014
Galr3 galanin receptor 3 0.014
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.014
Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.013
Htr3a 5-hydroxytryptamine (serotonin) receptor 3A 0.013
Inhbc inhibin beta-C 0.013
Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A 0.013
Spnb1 spectrin beta 1 0.013
D19Wsu162e DNA segment, Chr 19, Wayne State University 162, expressed 0.013
Kl klotho 0.013
Klhl9 kelch-like 9 (Drosophila) 0.013
Phf1 PHD finger protein 1 0.013
Phyh phytanoyl-CoA hydroxylase 0.013
Socs1 suppressor of cytokine signaling 1 0.012
Txnip thioredoxin interacting protein 0.012
Klf12 Kruppel-like factor 12 0.012
Osr1 odd-skipped related 1 (Drosophila) 0.012
Drd2 dopamine receptor D2 0.012
Fbxo11 F-box protein 11 0.012
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Rattus norvegicus
Name Description Probability Func Analog Organism
Serinc1 serine incorporator 1 0.297
Dbp D site of albumin promoter (albumin D-box) binding protein 0.185
Snrpb small nuclear ribonucleoprotein polypeptides B and B1 0.152
Pgm1 phosphoglucomutase 1 0.106
Rab1b RAB1B, member RAS oncogene family 0.084
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.076
Eef2 eukaryotic translation elongation factor 2 0.070
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.069
Etfdh electron-transferring-flavoprotein dehydrogenase 0.065
Ugp2 UDP-glucose pyrophosphorylase 2 0.058
Sypl1 synaptophysin-like 1 0.053
Gpi glucose phosphate isomerase 0.049
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.049
Ptp4a1 protein tyrosine phosphatase type IVA, member 1 0.048
Pygm phosphorylase, glycogen, muscle 0.044
Hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit 0.041
Acyp2 acylphosphatase 2, muscle type 0.038
Syngr2 synaptogyrin 2 0.036
Pfn1 profilin 1 0.034
Pkm2 pyruvate kinase, muscle 0.032
Irs1 insulin receptor substrate 1 0.028
Nup153 nucleoporin 153 0.027
Ccnd3 cyclin D3 0.027
Csnk1g2 casein kinase 1, gamma 2 0.027
Gpam glycerol-3-phosphate acyltransferase, mitochondrial 0.026
Timp3 TIMP metallopeptidase inhibitor 3 0.024
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.024
Aldoa aldolase A, fructose-bisphosphate 0.023
Ube2v2 ubiquitin-conjugating enzyme E2 variant 2 0.023
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.022
Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 0.022
Vdac1 voltage-dependent anion channel 1 0.021
Oaz1 ornithine decarboxylase antizyme 1 0.021
Gps1 G protein pathway suppressor 1 0.021
Usf2 upstream transcription factor 2, c-fos interacting 0.021
Fez2 fasciculation and elongation protein zeta 2 (zygin II) 0.021
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.021
Acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.020
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.020
Slc26a2 solute carrier family 26 (sulfate transporter), member 2 0.019
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.018
LOC100362155 cysteine and histidine rich 1 0.018
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.018
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.018
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.017
Rps8 ribosomal protein S8 0.017
Hibadh 3-hydroxyisobutyrate dehydrogenase 0.017
Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.017
Tef thyrotrophic embryonic factor 0.016
Lama2 laminin, alpha 2 0.016
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.015
Cops7a COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) 0.015
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.015
Acvr1 activin A receptor, type I 0.015
Cyfip2 cytoplasmic FMR1 interacting protein 2 0.014
Smad7 SMAD family member 7 0.014
Txnl1 thioredoxin-like 1 0.014
Gja1 gap junction protein, alpha 1 0.014
Mug1 murinoglobulin 1 0.014
Sgk2 serum/glucocorticoid regulated kinase 2 0.014
Akap1 A kinase (PRKA) anchor protein 1 0.014
Phka1 phosphorylase kinase, alpha 1 0.013
Ndrg2 N-myc downstream regulated gene 2 0.013
Pfkm phosphofructokinase, muscle 0.013
Gria2 glutamate receptor, ionotropic, AMPA 2 0.013
Clcn4-2 chloride channel 4-2 0.013
Cdk4 cyclin-dependent kinase 4 0.013
Ldlr low density lipoprotein receptor 0.012
Eif3f eukaryotic translation initiation factor 3, subunit F 0.012
Ak1 adenylate kinase 1 0.012
Nf1 neurofibromin 1 0.012
Dcun1d5 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) 0.012
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.011
Chordc1 cysteine and histidine-rich domain (CHORD)-containing 1 0.011
Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.011
Ldhb lactate dehydrogenase B 0.011
Met met proto-oncogene 0.011
Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.011
Me1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.011
Pdk2 pyruvate dehydrogenase kinase, isozyme 2 0.011
Guca2a guanylate cyclase activator 2a (guanylin) 0.011
Nnt nicotinamide nucleotide transhydrogenase 0.011
Acaca acetyl-coenzyme A carboxylase alpha 0.011
Egln3 EGL nine homolog 3 (C. elegans) 0.011
Ptk2b PTK2B protein tyrosine kinase 2 beta 0.010
Fgfr1 Fibroblast growth factor receptor 1 0.010
Zfp364 zinc finger protein 364 0.010
Vldlr very low density lipoprotein receptor 0.010
Hist1h1a histone cluster 1, H1a 0.010
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.010
Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 0.010
Orm1 orosomucoid 1 0.010