The network for 'lipid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ERG11 Erg11p 0.999
ERG25 Erg25p 0.995
ERG3 Erg3p 0.992
ERG5 Erg5p 0.991
ERG26 Erg26p 0.972
ERG28 Erg28p 0.938
ERG4 Erg4p 0.935
ERG7 Erg7p 0.930
INO2 Ino2p 0.916
ERG24 Erg24p 0.916
ERG27 Erg27p 0.891
ERG6 Erg6p 0.884
CHO1 Cho1p 0.869
ERG1 Erg1p 0.852
PSD1 Psd1p 0.845
ACC1 Acc1p 0.839
LAC1 Lac1p 0.833
LAG1 Lag1p 0.820
LCB1 Lcb1p 0.797
SCS7 Scs7p 0.780
GPI8 Gpi8p 0.767
LAS21 Las21p 0.686
SNF1 Snf1p 0.672
MDM35 Mdm35p 0.668
SLC1 Slc1p 0.657
YJU3 Yju3p 0.656
SIN3 Sin3p 0.634
GPI2 Gpi2p 0.621
FAS1 Fas1p 0.620
GSF2 Gsf2p 0.609
ERG8 Erg8p 0.595
ERG10 Erg10p 0.582
TOR2 Tor2p 0.573
PLB2 Plb2p 0.555
CDS1 Cds1p 0.533
NEM1 Nem1p 0.529
SAM2 Sam2p 0.511
PAH1 Pah1p 0.497
FAT1 Fat1p 0.457
SLG1 Slg1p 0.457
ROM2 Rom2p 0.454
SRV2 Srv2p 0.452
RIM101 Rim101p 0.450
FAB1 Fab1p 0.448
ERG13 Erg13p 0.422
IMD2 Imd2p 0.418
PHO86 Pho86p 0.411
GUP1 Gup1p 0.397
OPI3 Opi3p 0.396
LCB2 Lcb2p 0.387
KIN82 Kin82p 0.367
FAS2 Fas2p 0.364
EPT1 Ept1p 0.361
ADR1 Adr1p 0.358
GAA1 Gaa1p 0.347
GPI17 Gpi17p 0.345
ERG9 Erg9p 0.344
CTI6 Cti6p 0.341
MLC1 Mlc1p 0.329
ERG2 Erg2p 0.328
EHT1 Eht1p 0.325
DNM1 Dnm1p 0.321
MVD1 Mvd1p 0.319
PER1 Per1p 0.314
ORM2 Orm2p 0.313
POG1 Pog1p 0.312
CHO2 Cho2p 0.308
AVO1 Avo1p 0.306
GWT1 Gwt1p 0.303
SNF3 Snf3p 0.297
SPF1 Spf1p 0.291
PHO88 Pho88p 0.290
GAB1 Gab1p 0.286
MET4 Met4p 0.284
STT4 Stt4p 0.278
ERG12 Erg12p 0.266
OPI1 Opi1p 0.258
ELO1 Elo1p 0.257
GLO3 Glo3p 0.255
PCL8 Pcl8p 0.253
MRP8 Mrp8p 0.252
YNL234W hypothetical protein 0.244
TVP38 Tvp38p 0.240
CAT8 Cat8p 0.240
MOB2 Mob2p 0.237
OLE1 Ole1p 0.236
GPI13 Gpi13p 0.232
RTS1 Rts1p 0.232
PTK2 Ptk2p 0.225
YAP7 Yap7p 0.224
ISC1 Isc1p 0.222
HAA1 Haa1p 0.221
SEF1 Sef1p 0.219
PDR17 Pdr17p 0.215
MIG2 Mig2p 0.212
ARV1 Arv1p 0.212
MIG3 Mig3p 0.211
HMG1 Hmg1p 0.211
IRE1 Ire1p 0.210
UPS1 Ups1p 0.210
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
elo-2 Protein ELO-2 0.907
pmt-1 Protein PMT-1 0.831
fat-4 Protein FAT-4 0.700
elo-6 Protein ELO-6 0.686
fat-2 Protein FAT-2 0.547
sur-5 Protein SUR-5 0.526
fat-6 Protein FAT-6 0.502
fat-1 Protein FAT-1 0.484
elo-5 Protein ELO-5 0.478
itr-1 Protein ITR-1 0.422
fat-3 Protein FAT-3 0.358
brp-1 Protein BRP-1 0.254
cpz-2 Protein CPZ-2 0.237
elo-1 Protein ELO-1 0.234
pes-9 Protein PES-9 0.222
CELE_Y43F8C.13 Protein Y43F8C.13 0.215
tag-320 Protein TAG-320 0.209
hpo-13 Protein HPO-13 0.189
mpk-1 Protein MPK-1 0.188
sptl-1 Protein SPTL-1 0.186
hpd-1 Protein HPD-1 0.173
let-767 Protein LET-767 0.171
bar-1 Protein BAR-1 0.165
pod-2 Protein POD-2 0.162
pho-1 Protein PHO-1 0.156
hpo-8 Protein HPO-8 0.151
gspd-1 Protein GSPD-1 0.150
lmp-1 Protein LMP-1 0.138
CELE_Y53C10A.5 Protein Y53C10A.5 0.137
R02F2.5 Protein R02F2.5 0.137
dct-18 Protein DCT-18 0.132
nhr-68 Protein NHR-68 0.127
gana-1 Protein GANA-1 0.126
cept-1 Protein CEPT-1 0.123
F32A5.3 Protein F32A5.3 0.122
sma-6 Protein SMA-6 0.112
ran-2 Protein RAN-2 0.110
tre-1 Protein TRE-1 0.110
let-23 Protein LET-23 0.103
dhs-4 Protein DHS-4 0.102
aqp-10 Protein AQP-10 0.099
CELE_F23H12.5 Protein F23H12.5 0.097
CELE_ZK1307.8 Protein ZK1307.8 0.093
acs-14 Protein ACS-14 0.089
acy-3 Protein ACY-3 0.084
ufd-2 Protein UFD-2 0.084
C48B4.1 Protein C48B4.1 0.084
CELE_F17C11.6 Protein F17C11.6 0.083
erd-2 Protein ERD-2 0.083
lbp-3 Protein LBP-3 0.081
F13E6.5 Protein F13E6.5 0.080
sptl-2 Protein SPTL-2 0.079
F48E8.3 Protein F48E8.3 0.079
raga-1 Protein RAGA-1 0.078
tpxl-1 Protein TPXL-1 0.077
pkg-1 Protein PKG-1 0.077
cysl-3 Protein CYSL-3 0.076
CELE_ZK1320.2 Protein ZK1320.2 0.074
F09E5.11 Protein F09E5.11 0.074
maoc-1 Protein MAOC-1 0.072
sem-5 Protein SEM-5 0.071
K02D7.1 Protein K02D7.1 0.070
T03G11.4 Protein T03G11.4 0.068
K11H12.8 Protein K11H12.8 0.068
T28D9.3 Protein T28D9.3 0.067
R11A8.5 Protein R11A8.5 0.064
cyp-35C1 Protein CYP-35C1 0.063
C48A7.2 Protein C48A7.2 0.062
C03A3.2 Protein C03A3.2 0.061
nhr-64 Protein NHR-64 0.061
egl-8 Protein EGL-8 0.061
R10H10.3 Protein R10H10.3 0.058
ugt-25 Protein UGT-25 0.057
tsp-14 Protein TSP-14 0.057
cdf-1 Protein CDF-1 0.056
ethe-1 Protein ETHE-1 0.056
CELE_C29F7.2 Protein C29F7.2 0.055
hmgs-1 Protein HMGS-1 0.054
lact-3 Protein LACT-3 0.053
CELE_T01B11.2 Protein T01B11.2 0.053
exc-7 Protein EXC-7 0.053
F46H5.7 Protein F46H5.7 0.053
rskn-1 Protein RSKN-1 0.053
K10D6.4 Protein K10D6.4 0.052
C11E4.6 Protein C11E4.6 0.051
cka-2 Protein CKA-2 0.051
C34D10.2 Protein C34D10.2 0.050
xpo-3 Protein XPO-3 0.049
sptl-3 Protein SPTL-3 0.049
T23F11.1 Protein T23F11.1 0.049
osm-11 Protein OSM-11 0.048
cyp-43A1 Protein CYP-43A1 0.048
CELE_C49C3.4 Protein C49C3.4 0.048
gob-1 Protein GOB-1 0.048
F22F7.1 Protein F22F7.1 0.047
acl-7 Protein ACL-7 0.047
ugt-23 Protein UGT-23 0.046
prk-1 Protein PRK-1 0.045
vha-14 Protein VHA-14 0.045
spp-8 Protein SPP-8 0.044
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.505
fgf3 fibroblast growth factor 3 0.234
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.216
apoa4 apolipoprotein A-IV 0.207
bmp2b bone morphogenetic protein 2b 0.191
lpp LIM domain containing preferred translocation partner in lipoma 0.186
ptgs1 prostaglandin-endoperoxide synthase 1 0.161
esr2b estrogen receptor 2b 0.157
ocrl oculocerebrorenal syndrome of Lowe 0.146
cldn2 claudin 2 0.146
mtp microsomal triglyceride transfer protein 0.143
sox9b SRY-box containing gene 9b 0.138
sox9a SRY-box containing gene 9a 0.138
gata6 GATA-binding protein 6 0.129
ptgs2a prostaglandin-endoperoxide synthase 2a 0.127
inha inhibin, alpha 0.121
cyp1a cytochrome P450, family 1, subfamily A 0.106
igf1ra insulin-like growth factor 1a receptor 0.100
fgfrl1b fibroblast growth factor receptor-like 1b 0.099
runx2b runt-related transcription factor 2b 0.098
fabp2 fatty acid binding protein 2, intestinal 0.090
lass2 LAG1 homolog, ceramide synthase 2 (S. cerevisiae) 0.090
cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 0.089
cldn1 claudin 1 0.088
lamc1 laminin, gamma 1 0.081
lhcgr luteinizing hormone/choriogonadotropin receptor 0.080
atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.080
hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.078
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.076
nkx2.3 NK2 transcription factor related 3 0.074
pbx1a pre-B-cell leukemia transcription factor 1a 0.072
cdx1a caudal type homeo box transcription factor 1 a 0.069
col11a1a collagen, type XI, alpha 1a 0.065
epas1b endothelial PAS domain protein 1b 0.063
rbp2a retinol binding protein 2a, cellular 0.062
plcg1 phospholipase C, gamma 1 0.062
hsd17b12b hydroxysteroid (17-beta) dehydrogenase 12b 0.061
fabp10a fatty acid binding protein 10a, liver basic 0.059
pvalb7 parvalbumin 7 0.058
ptgds prostaglandin D2 synthase 0.058
mst1 macrophage stimulating 1 (hepatocyte growth factor-like) 0.057
fgfr2 fibroblast growth factor receptor 2 0.054
hsd17b12a hydroxysteroid (17-beta) dehydrogenase 12a 0.053
hnf4a hepatocyte nuclear factor 4, alpha 0.050
foxa1 forkhead box A1 0.049
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.048
fsta follistatin a 0.048
frem3 Fras1 related extracellular matrix 3 0.048
mstnb myostatin b 0.047
entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.047
vtg1 vitellogenin 1 0.046
slc8a1b solute carrier family 8 (sodium/calcium exchanger), member 1b 0.045
hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 0.045
tm4sf4 transmembrane 4 L six family member 4 0.044
ip6k2 inositol hexaphosphate kinase 2 0.044
pomt1 protein-O-mannosyltransferase 1 0.044
si:dkeyp-110g5.2 si:dkeyp-110g5.2 0.042
jag1b jagged 1b 0.041
inhbaa inhibin, beta Aa 0.040
gfer growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) 0.040
atp1a1a.3 ATPase, Na+/K+ transporting, alpha 1a.3 polypeptide 0.039
vmhc ventricular myosin heavy chain 0.039
slc37a4a solute carrier family 37 (glucose-6-phosphate transporter), member 4a 0.038
elovl7b ELOVL family member 7, elongation of long chain fatty acids (yeast) b 0.038
cldnb claudin b 0.038
dzip1 DAZ interacting protein 1 0.037
ar androgen receptor 0.037
cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a 0.037
igf1rb insulin-like growth factor 1b receptor 0.036
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.036
c3b complement component c3b 0.035
rnf128a ring finger protein 128a 0.035
zgc:161979 zgc:161979 0.034
tyrp1b tyrosinase-related protein 1b 0.034
si:ch211-93f2.1 si:ch211-93f2.1 0.034
hnf1ba HNF1 homeobox Ba 0.034
fetub fetuin B 0.033
mib mind bomb 0.033
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.033
runx2a runt-related transcription factor 2a 0.032
paqr7b progestin and adipoQ receptor family member VII, b 0.032
slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 0.032
slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.032
slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.032
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.031
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.031
ela2l elastase 2 like 0.031
tbx1 T-box 1 0.031
fam116b family with sequence similarity 116, member B 0.031
btr30 bloodthirsty-related gene family, member 30 0.030
ttpa tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) 0.030
rgs4 regulator of G-protein signalling 4 0.030
ren renin 0.030
sox21b SRY-box containing gene 21 b 0.030
apobl apolipoprotein B, like 0.030
gli1 GLI-Kruppel family member 1 0.030
cryaa crystallin, alpha A 0.030
ins preproinsulin 0.030
fras1 Fraser syndrome 1 0.030
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.029
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Dhc64C Dynein heavy chain 64C 0.717
Fatp Fatty acid (long chain) transport protein 0.653
Fs(2)Ket Female sterile (2) Ketel 0.400
CG16904 CG16904 gene product from transcript CG16904-RA 0.373
Ugt35a UDP-glycosyltransferase 35a 0.359
CG3523 CG3523 gene product from transcript CG3523-RA 0.356
CG9990 CG9990 gene product from transcript CG9990-RA 0.344
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.296
Cyp12d1-p CG30489 gene product from transcript CG30489-RA 0.291
Rab11 Rab-protein 11 0.229
Arp14D Actin-related protein 14D 0.225
Rfabg Retinoid- and fatty acid-binding glycoprotein 0.213
dib disembodied 0.209
foi fear-of-intimacy 0.199
InR Insulin-like receptor 0.189
CG3164 CG3164 gene product from transcript CG3164-RA 0.183
CG6660 CG6660 gene product from transcript CG6660-RA 0.166
CG9053 CG9053 gene product from transcript CG9053-RA 0.165
CG18609 CG18609 gene product from transcript CG18609-RA 0.165
dock dreadlocks 0.154
sad shadow 0.151
mof males absent on the first 0.150
CG15828 CG15828 gene product from transcript CG15828-RC 0.148
CG9458 CG9458 gene product from transcript CG9458-RA 0.146
Mtp Microsomal triacylglycerol transfer protein 0.145
Yp2 Yolk protein 2 0.144
Lsd-2 Lipid storage droplet-2 0.135
Cyp12d1-d CG33503 gene product from transcript CG33503-RA 0.134
CG1516 CG1516 gene product from transcript CG1516-RP 0.133
mi minus 0.133
Cyp9f2 CG11466 gene product from transcript CG11466-RB 0.133
CG15531 CG15531 gene product from transcript CG15531-RB 0.129
srp serpent 0.129
CG7910 CG7910 gene product from transcript CG7910-RA 0.123
eloF elongase F 0.122
CG30008 CG30008 gene product from transcript CG30008-RA 0.120
rasp CG11495 gene product from transcript CG11495-RA 0.120
Letm1 CG4589 gene product from transcript CG4589-RB 0.118
ttm50 tiny tim 50 0.113
Hr96 Hormone receptor-like in 96 0.112
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.111
CG4389 CG4389 gene product from transcript CG4389-RA 0.110
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.110
Cyp6g1 CG8453 gene product from transcript CG8453-RA 0.109
Fad2 CG7923 gene product from transcript CG7923-RA 0.098
CG6834 CG6834 gene product from transcript CG6834-RA 0.097
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.095
CG5508 CG5508 gene product from transcript CG5508-RA 0.094
Acox57D-p acyl-Coenzyme A oxidase at 57D proximal 0.093
desat1 CG5887 gene product from transcript CG5887-RA 0.093
CG6283 CG6283 gene product from transcript CG6283-RA 0.092
CG17734 CG17734 gene product from transcript CG17734-RA 0.089
Thor CG8846 gene product from transcript CG8846-RA 0.088
CG14820 CG14820 gene product from transcript CG14820-RA 0.088
mbl muscleblind 0.088
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.085
Trf2 TATA box binding protein-related factor 2 0.085
CSN4 COP9 complex homolog subunit 4 0.084
step steppke 0.083
Cyp4e2 Cytochrome P450-4e2 0.081
Adh Alcohol dehydrogenase 0.079
Cyp28d1 CG10833 gene product from transcript CG10833-RA 0.079
CG4020 CG4020 gene product from transcript CG4020-RA 0.078
alpha-Est7 alpha-Esterase-7 0.077
ric8a CG15797 gene product from transcript CG15797-RA 0.075
Sod Superoxide dismutase 0.074
CG12672 CG12672 gene product from transcript CG12672-RA 0.074
CG2064 CG2064 gene product from transcript CG2064-RA 0.073
dia diaphanous 0.073
CG9953 CG9953 gene product from transcript CG9953-RA 0.073
Npc1a Niemann-Pick type C-1a 0.072
Phm Peptidylglycine-alpha-hydroxylating monooxygenase 0.071
Cyp28a5 CG8864 gene product from transcript CG8864-RA 0.070
Cyp4g1 Cytochrome P450-4g1 0.069
CG9459 CG9459 gene product from transcript CG9459-RA 0.067
jar jaguar 0.067
CG2765 CG2765 gene product from transcript CG2765-RE 0.067
Atg18 Autophagy-specific gene 18 0.066
Yp3 Yolk protein 3 0.066
CG12428 CG12428 gene product from transcript CG12428-RB 0.066
CG8814 CG8814 gene product from transcript CG8814-RA 0.065
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.063
dei delilah 0.063
CG1927 CG1927 gene product from transcript CG1927-RA 0.062
CG5162 CG5162 gene product from transcript CG5162-RA 0.062
Epac CG34392 gene product from transcript CG34392-RC 0.061
Hph HIF prolyl hydroxylase 0.061
CG5335 CG5335 gene product from transcript CG5335-RA 0.061
CG4558 CG4558 gene product from transcript CG4558-RA 0.061
Pect Phosphoethanolamine cytidylyltransferase 0.060
CG1443 CG1443 gene product from transcript CG1443-RA 0.060
CG9904 CG9904 gene product from transcript CG9904-RA 0.060
spas spastin 0.060
Hop Hsp70/Hsp90 organizing protein homolog 0.060
CG4753 CG4753 gene product from transcript CG4753-RB 0.059
Ent2 Equilibrative nucleoside transporter 2 0.058
laza lazaro 0.058
Tequila CG4821 gene product from transcript CG4821-RE 0.058
CG14194 CG14194 gene product from transcript CG14194-RA 0.057
CG12262 CG12262 gene product from transcript CG12262-RA 0.057
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
DHCR7 7-dehydrocholesterol reductase 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
FGFR2 fibroblast growth factor receptor 2 0.999
HNF4A hepatocyte nuclear factor 4, alpha 0.999
SC4MOL sterol-C4-methyl oxidase-like 0.996
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.995
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.995
FDPS farnesyl diphosphate synthase 0.993
FGF1 fibroblast growth factor 1 (acidic) 0.992
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.979
SREBF2 sterol regulatory element binding transcription factor 2 0.978
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.970
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.969
C14orf1 chromosome 14 open reading frame 1 0.965
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.964
SKIL SKI-like oncogene 0.961
SQLE squalene epoxidase 0.959
ALB albumin 0.956
CREBBP CREB binding protein 0.956
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.950
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.949
VEGFA vascular endothelial growth factor A 0.943
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.937
APOA1 apolipoprotein A-I 0.933
RXRA retinoid X receptor, alpha 0.921
IL1R1 interleukin 1 receptor, type I 0.911
INSIG1 insulin induced gene 1 0.909
GGT1 gamma-glutamyltransferase 1 0.905
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.899
GPAA1 glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) 0.889
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.874
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.872
ACACA acetyl-CoA carboxylase alpha 0.860
IRS1 insulin receptor substrate 1 0.855
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.831
GH1 growth hormone 1 0.824
DHCR24 24-dehydrocholesterol reductase 0.823
AR androgen receptor 0.821
FGFR1 fibroblast growth factor receptor 1 0.812
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.795
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.779
BCL3 B-cell CLL/lymphoma 3 0.777
INSR insulin receptor 0.765
LDLR low density lipoprotein receptor 0.762
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.743
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.719
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.710
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.702
BRCA1 breast cancer 1, early onset 0.690
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.689
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.678
NOS1 nitric oxide synthase 1 (neuronal) 0.671
PDPK1 3-phosphoinositide dependent protein kinase-1 0.638
EBP emopamil binding protein (sterol isomerase) 0.624
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.623
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.622
MVD mevalonate (diphospho) decarboxylase 0.621
ACAT2 acetyl-CoA acetyltransferase 2 0.620
IDI1 isopentenyl-diphosphate delta isomerase 1 0.609
ESR1 estrogen receptor 1 0.608
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.597
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.589
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.586
NME2 non-metastatic cells 2, protein (NM23B) expressed in 0.582
LAMP1 lysosomal-associated membrane protein 1 0.579
SMAD3 SMAD family member 3 0.566
FASN fatty acid synthase 0.556
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.542
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.522
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.520
HP haptoglobin 0.507
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.503
EGFR epidermal growth factor receptor 0.498
CHUK conserved helix-loop-helix ubiquitous kinase 0.495
BMPR1A bone morphogenetic protein receptor, type IA 0.489
GH2 growth hormone 2 0.483
GGTLC1 gamma-glutamyltransferase light chain 1 0.477
FADS1 fatty acid desaturase 1 0.451
ACLY ATP citrate lyase 0.438
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.429
APOC1 apolipoprotein C-I 0.425
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.423
CTGF connective tissue growth factor 0.411
TXN thioredoxin 0.402
ACAA2 acetyl-CoA acyltransferase 2 0.396
MVK mevalonate kinase 0.393
PFKL phosphofructokinase, liver 0.387
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.382
SYK spleen tyrosine kinase 0.382
NOXA1 NADPH oxidase activator 1 0.379
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.376
MPDZ multiple PDZ domain protein 0.375
GRB10 growth factor receptor-bound protein 10 0.370
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.367
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.361
ZFYVE9 zinc finger, FYVE domain containing 9 0.357
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.353
ABI1 abl-interactor 1 0.353
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.352
IL1B interleukin 1, beta 0.347
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Cyp51 cytochrome P450, family 51 1.000
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 0.997
Pax8 paired box gene 8 0.996
Idi1 isopentenyl-diphosphate delta isomerase 0.991
Rarg retinoic acid receptor, gamma 0.989
Pten phosphatase and tensin homolog 0.988
Sqle squalene epoxidase 0.987
Lepr leptin receptor 0.986
Ar androgen receptor 0.976
Insr insulin receptor 0.974
Sc4mol sterol-C4-methyl oxidase-like 0.972
Ldlr low density lipoprotein receptor 0.964
Cps1 carbamoyl-phosphate synthetase 1 0.960
Kl klotho 0.944
Dhcr7 7-dehydrocholesterol reductase 0.928
Pnpla2 patatin-like phospholipase domain containing 2 0.913
Mvd mevalonate (diphospho) decarboxylase 0.908
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.888
Ghr growth hormone receptor 0.886
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.883
Thbs1 thrombospondin 1 0.881
Otc ornithine transcarbamylase 0.880
Prlr prolactin receptor 0.878
Scd1 stearoyl-Coenzyme A desaturase 1 0.878
Esr1 estrogen receptor 1 (alpha) 0.869
Sc5d sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) 0.860
Dmgdh dimethylglycine dehydrogenase precursor 0.852
Lss lanosterol synthase 0.845
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.841
Acly ATP citrate lyase 0.831
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.825
Fasn fatty acid synthase 0.824
Bscl2 Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) 0.769
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.765
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.764
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.758
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.753
Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 0.750
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.741
Acat2 acetyl-Coenzyme A acetyltransferase 2 0.734
Apob apolipoprotein B 0.729
Pparg peroxisome proliferator activated receptor gamma 0.728
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.711
Lef1 lymphoid enhancer binding factor 1 0.708
Crh corticotropin releasing hormone 0.707
Nsdhl NAD(P) dependent steroid dehydrogenase-like 0.704
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.694
Irs2 insulin receptor substrate 2 0.691
Trp53 transformation related protein 53 0.686
Vdr vitamin D receptor 0.685
Dram2 VDNA-damage regulated autophagy modulator 2 0.685
Bmp4 bone morphogenetic protein 4 0.680
Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 0.678
Pax2 paired box gene 2 0.675
Mup19 major urinary protein 19 0.670
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.658
Dhcr24 24-dehydrocholesterol reductase 0.652
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.648
Crp C-reactive protein, pentraxin-related 0.645
Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 0.637
F12 coagulation factor XII (Hageman factor) 0.631
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.629
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.621
Ren1 renin 1 structural 0.613
Stard4 StAR-related lipid transfer (START) domain containing 4 0.612
Hnf4a hepatic nuclear factor 4, alpha 0.610
Sox9 SRY-box containing gene 9 0.610
Apoa1 apolipoprotein A-I 0.608
Timd2 T-cell immunoglobulin and mucin domain containing 2 0.606
Npc1 Niemann Pick type C1 0.604
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.603
Apoe apolipoprotein E 0.596
Bmp7 bone morphogenetic protein 7 0.594
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.592
Mup10 major urinary protein 10 0.590
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.586
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.584
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.581
Aldob aldolase B, fructose-bisphosphate 0.574
Foxa2 forkhead box A2 0.573
Hao2 hydroxyacid oxidase 2 0.572
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.570
Rdh11 retinol dehydrogenase 11 0.569
Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 0.564
Grb10 growth factor receptor bound protein 10 0.558
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.552
G6pc glucose-6-phosphatase, catalytic 0.551
F9 coagulation factor IX 0.545
Pcyt2 phosphate cytidylyltransferase 2, ethanolamine 0.544
Slc12a1 solute carrier family 12, member 1 0.542
Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 0.542
Duox2 dual oxidase 2 0.540
Aacs acetoacetyl-CoA synthetase 0.540
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.537
Pik3c2g phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide 0.536
Idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.533
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.530
Slco1b2 solute carrier organic anion transporter family, member 1b2 0.527
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 0.522
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.521
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 1.000
Cyp51 cytochrome P450, family 51 1.000
Sc4mol sterol-C4-methyl oxidase-like 0.998
Idi1 isopentenyl-diphosphate delta isomerase 1 0.997
Fdft1 farnesyl diphosphate farnesyl transferase 1 0.995
Acat3 acetyl-Coenzyme A acetyltransferase 3 0.994
Fasn fatty acid synthase 0.990
Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.971
Acly ATP citrate lyase 0.968
Sqle squalene epoxidase 0.966
Fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) 0.929
Dhcr7 7-dehydrocholesterol reductase 0.926
Cd36 CD36 molecule (thrombospondin receptor) 0.926
Insig1 insulin induced gene 1 0.868
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 0.776
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.716
Dhcr24 24-dehydrocholesterol reductase 0.681
Fads1 fatty acid desaturase 1 0.604
Gpam glycerol-3-phosphate acyltransferase, mitochondrial 0.585
Clca4 chloride channel accessory 4 0.527
Vim vimentin 0.508
Sc5dl sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like 0.464
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 0.410
Irs1 insulin receptor substrate 1 0.407
Nsdhl NAD(P) dependent steroid dehydrogenase-like 0.379
S100a9 S100 calcium binding protein A9 0.360
Scd1 stearoyl-Coenzyme A desaturase 1 0.346
Tkt transketolase 0.344
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.333
Idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.331
RGD1305689 similar to DNA segment, Chr 14, ERATO Doi 449, expressed 0.328
Pla2g2c phospholipase A2, group IIC 0.327
Pnpla2 patatin-like phospholipase domain containing 2 0.319
Acss2 acyl-CoA synthetase short-chain family member 2 0.312
Agxt alanine-glyoxylate aminotransferase 0.310
Dbp D site of albumin promoter (albumin D-box) binding protein 0.304
Prl8a2 prolactin family 8, subfamily a, member 2 0.295
Anxa2 annexin A2 0.294
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.291
Acadm acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain 0.287
Gzmb granzyme B 0.284
Fads2 fatty acid desaturase 2 0.271
Olr1696 olfactory receptor 1696 0.269
Anxa5 annexin A5 0.269
Orm1 orosomucoid 1 0.263
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.262
Etfdh electron-transferring-flavoprotein dehydrogenase 0.249
Rhox5 reproductive homeobox 5 0.248
Lgals4 lectin, galactoside-binding, soluble, 4 0.247
Pcyt2 phosphate cytidylyltransferase 2, ethanolamine 0.246
Kcne1 potassium voltage-gated channel, Isk-related family, member 1 0.245
Galnt5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 0.244
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.243
Pth2r parathyroid hormone 2 receptor 0.239
Apba3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.239
RGD1566083 similar to hypothetical protein MGC24047 0.237
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.236
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.235
Aqp9 aquaporin 9 0.234
Pygl phosphorylase, glycogen, liver 0.233
Adam2 ADAM metallopeptidase domain 2 0.228
Gucy2d guanylate cyclase 2d 0.226
Pxmp2 peroxisomal membrane protein 2 0.224
Adipor2 adiponectin receptor 2 0.222
Prlr prolactin receptor 0.218
Pnlip pancreatic lipase 0.218
Cfd complement factor D (adipsin) 0.217
Tmem97 transmembrane protein 97 0.216
Mrgprx3 MAS-related GPR, member X3 0.215
Mmp8 matrix metallopeptidase 8 0.213
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.206
Acaca acetyl-coenzyme A carboxylase alpha 0.203
Kcnh5 potassium voltage-gated channel, subfamily H (eag-related), member 5 0.202
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.199
Slc25a1 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 0.197
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.196
Cpt1b carnitine palmitoyltransferase 1b, muscle 0.195
Vcsa2 variable coding sequence A2 0.195
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.193
Agtr1b angiotensin II receptor, type 1b 0.191
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.191
Rdh7 retinol dehydrogenase 7 0.190
Hoxd9 homeo box D9 0.189
Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) 0.188
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.188
Cd40lg CD40 ligand 0.187
Pip prolactin induced protein 0.186
Slc22a3 solute carrier family 22 (extraneuronal monoamine transporter), member 3 0.178
Fam108b1 family with sequence similarity 108, member B1 0.177
Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M 0.177
Cit citron 0.177
Hcrtr2 hypocretin (orexin) receptor 2 0.177
Tm7sf2 transmembrane 7 superfamily member 2 0.175
S100a11 S100 calcium binding protein A11 (calizzarin) 0.174
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.174
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.173
Acsl1 acyl-CoA synthetase long-chain family member 1 0.173
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.172
Aqp7 aquaporin 7 0.172
Fam126b family with sequence similarity 126, member B 0.170