The network for 'glucose metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glucose metabolic process

The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ADH1 Adh1p 0.964
ENO2 Eno2p 0.918
FBA1 Fba1p 0.916
PDC1 Pdc1p 0.911
FYV10 Fyv10p 0.889
ENO1 Eno1p 0.887
CAK1 Cak1p 0.856
GND1 Gnd1p 0.856
PGK1 Pgk1p 0.834
UGP1 Ugp1p 0.810
TDH2 Tdh2p 0.801
GID8 Gid8p 0.778
GND2 Gnd2p 0.728
ERR3 Err3p 0.725
WWM1 Wwm1p 0.655
ALD6 Ald6p 0.652
MOH1 Moh1p 0.646
GPM1 Gpm1p 0.630
TPI1 Tpi1p 0.569
TDH1 Tdh1p 0.567
GAL83 Gal83p 0.565
TDH3 Tdh3p 0.466
PFK1 Pfk1p 0.433
GID7 Gid7p 0.420
CAT8 Cat8p 0.381
GIP2 Gip2p 0.355
TAL1 Tal1p 0.342
HXK2 Hxk2p 0.334
NDE2 Nde2p 0.319
HOP1 Hop1p 0.319
PYC2 Pyc2p 0.298
PGI1 Pgi1p 0.277
SDS24 Sds24p 0.258
RRD1 Rrd1p 0.251
SIP1 Sip1p 0.229
RMD5 Rmd5p 0.215
MLS1 Mls1p 0.203
ADH3 Adh3p 0.201
PIG2 Pig2p 0.198
RDS2 Rds2p 0.197
ROD1 Rod1p 0.195
GSY2 Gsy2p 0.190
PGM2 Pgm2p 0.188
YAP6 Yap6p 0.187
VID30 Vid30p 0.186
PDI1 Pdi1p 0.185
PCL10 Pcl10p 0.181
GPH1 Gph1p 0.175
VID28 Vid28p 0.173
BBC1 Bbc1p 0.173
PYC1 Pyc1p 0.171
MVD1 Mvd1p 0.171
TMA10 Tma10p 0.160
CDC19 Cdc19p 0.158
BDH1 Bdh1p 0.152
PCH2 Pch2p 0.151
ZWF1 Zwf1p 0.150
REG1 Reg1p 0.141
YLR345W hypothetical protein 0.140
PCL9 Pcl9p 0.138
CMK2 Cmk2p 0.134
CIT2 Cit2p 0.134
SWE1 Swe1p 0.120
SPE3 Spe3p 0.117
PFK2 Pfk2p 0.117
MDH2 Mdh2p 0.116
MBR1 Mbr1p 0.115
YLR177W hypothetical protein 0.113
SSH4 Ssh4p 0.112
GDB1 Gdb1p 0.111
GPM2 Gpm2p 0.110
AZF1 Azf1p 0.109
ICL1 Icl1p 0.109
SNF1 Snf1p 0.108
YEL023C hypothetical protein 0.107
TRR1 Trr1p 0.100
GSY1 Gsy1p 0.100
SSA4 Ssa4p 0.097
SPO1 Spo1p 0.097
NCE103 Nce103p 0.097
YLR257W hypothetical protein 0.095
SOL1 Sol1p 0.094
RGC1 Rgc1p 0.093
HUG1 Hug1p 0.093
RED1 Red1p 0.092
GAC1 Gac1p 0.091
PHO81 Pho81p 0.089
YMR210W hypothetical protein 0.088
CLB6 Clb6p 0.087
ALD4 Ald4p 0.086
ERT1 Ert1p 0.086
PSK1 Psk1p 0.081
YCL042W hypothetical protein 0.080
GAL7 Gal7p 0.079
KIC1 Kic1p 0.077
RCK1 Rck1p 0.077
SAP4 Sap4p 0.076
ALD2 Ald2p 0.076
PET9 Pet9p 0.076
THO2 Tho2p 0.075
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pgk Phosphoglycerate kinase 0.062
Gpdh Glycerol 3 phosphate dehydrogenase 0.044
Pgm Phosphogluconate mutase 0.040
Got2 Glutamate oxaloacetate transaminase 2 0.031
Tpi Triose phosphate isomerase 0.025
Pgi Phosphoglucose isomerase 0.019
Idh Isocitrate dehydrogenase 0.018
GlyP Glycogen phosphorylase 0.017
PyK Pyruvate kinase 0.017
CG7920 CG7920 gene product from transcript CG7920-RA 0.016
Pgd Phosphogluconate dehydrogenase 0.014
Thor CG8846 gene product from transcript CG8846-RA 0.013
hep hemipterous 0.012
CG7998 CG7998 gene product from transcript CG7998-RA 0.012
Men Malic enzyme 0.012
CG5362 CG5362 gene product from transcript CG5362-RA 0.012
Eno Enolase 0.011
InR Insulin-like receptor 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
INSR insulin receptor 0.992
CREBBP CREB binding protein 0.958
ESR1 estrogen receptor 1 0.905
IRS1 insulin receptor substrate 1 0.833
AR androgen receptor 0.608
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.559
NCOA1 nuclear receptor coactivator 1 0.480
IRS2 insulin receptor substrate 2 0.420
ENO2 enolase 2 (gamma, neuronal) 0.410
PGK1 phosphoglycerate kinase 1 0.380
GRB10 growth factor receptor-bound protein 10 0.340
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.321
RXRA retinoid X receptor, alpha 0.320
SMAD3 SMAD family member 3 0.305
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.288
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.286
EGFR epidermal growth factor receptor 0.233
C1QA complement component 1, q subcomponent, A chain 0.221
LIN7B lin-7 homolog B (C. elegans) 0.216
KAT2B K(lysine) acetyltransferase 2B 0.204
EP300 E1A binding protein p300 0.203
TADA3 transcriptional adaptor 3 0.188
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.178
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.173
GHR growth hormone receptor 0.163
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.160
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.157
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.150
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.145
SQSTM1 sequestosome 1 0.133
CREB1 cAMP responsive element binding protein 1 0.133
ACACA acetyl-CoA carboxylase alpha 0.128
HNF4A hepatocyte nuclear factor 4, alpha 0.119
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.118
NOXA1 NADPH oxidase activator 1 0.109
HK1 hexokinase 1 0.108
ISG15 ISG15 ubiquitin-like modifier 0.107
IFI27 interferon, alpha-inducible protein 27 0.107
DCAF7 DDB1 and CUL4 associated factor 7 0.105
IGF1R insulin-like growth factor 1 receptor 0.103
NCOA6 nuclear receptor coactivator 6 0.099
PDPK1 3-phosphoinositide dependent protein kinase-1 0.093
RARA retinoic acid receptor, alpha 0.091
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.084
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.080
NCF1 neutrophil cytosolic factor 1 0.080
SH2B1 SH2B adaptor protein 1 0.079
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.077
FHL2 four and a half LIM domains 2 0.076
GPI glucose-6-phosphate isomerase 0.075
GSK3B glycogen synthase kinase 3 beta 0.074
ALDOA aldolase A, fructose-bisphosphate 0.074
IFI44L interferon-induced protein 44-like 0.073
TRRAP transformation/transcription domain-associated protein 0.072
SORBS3 sorbin and SH3 domain containing 3 0.071
BAD BCL2-associated agonist of cell death 0.070
NCOR2 nuclear receptor corepressor 2 0.069
MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 0.069
IFI44 interferon-induced protein 44 0.069
CREBZF CREB/ATF bZIP transcription factor 0.067
TTR transthyretin 0.067
IFI6 interferon, alpha-inducible protein 6 0.066
MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 0.066
LCK lymphocyte-specific protein tyrosine kinase 0.065
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.064
TRIB3 tribbles homolog 3 (Drosophila) 0.064
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.059
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.059
HIPK2 homeodomain interacting protein kinase 2 0.058
FOXO1 forkhead box O1 0.058
MX2 myxovirus (influenza virus) resistance 2 (mouse) 0.057
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.057
HSPB1 heat shock 27kDa protein 1 0.056
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.056
SIRT1 sirtuin 1 0.053
ZNF746 zinc finger protein 746 0.049
PINK1 PTEN induced putative kinase 1 0.048
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.047
SORBS1 sorbin and SH3 domain containing 1 0.047
CCDC101 coiled-coil domain containing 101 0.046
C1QB complement component 1, q subcomponent, B chain 0.045
TKT transketolase 0.045
C5orf41 chromosome 5 open reading frame 41 0.044
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.043
RSAD2 radical S-adenosyl methionine domain containing 2 0.042
TRIM23 tripartite motif containing 23 0.042
PROX1 prospero homeobox 1 0.041
IRF7 interferon regulatory factor 7 0.041
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.040
FOXO3 forkhead box O3 0.039
PPARG peroxisome proliferator-activated receptor gamma 0.039
USP18 ubiquitin specific peptidase 18 0.039
EPSTI1 epithelial stromal interaction 1 (breast) 0.038
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.038
ATXN7 ataxin 7 0.038
SYK spleen tyrosine kinase 0.037
BST2 bone marrow stromal cell antigen 2 0.037
ATF3 activating transcription factor 3 0.037
DUSP5 dual specificity phosphatase 5 0.037
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.036
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Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 0.993
Insr insulin receptor 0.982
Lep leptin 0.981
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.977
Pparg peroxisome proliferator activated receptor gamma 0.970
Clock circadian locomotor output cycles kaput 0.967
Per2 period homolog 2 (Drosophila) 0.967
Esr1 estrogen receptor 1 (alpha) 0.959
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.936
Cry2 cryptochrome 2 (photolyase-like) 0.925
Ins2 insulin II 0.891
Nos1 nitric oxide synthase 1, neuronal 0.842
Npy1r neuropeptide Y receptor Y1 0.818
Igf1r insulin-like growth factor I receptor 0.793
Irs2 insulin receptor substrate 2 0.782
Prlr prolactin receptor 0.731
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.701
Onecut1 one cut domain, family member 1 0.694
Ren1 renin 1 structural 0.682
Atf2 activating transcription factor 2 0.670
Jun Jun oncogene 0.655
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.624
Pten phosphatase and tensin homolog 0.611
Irs1 insulin receptor substrate 1 0.589
Clk4 CDC like kinase 4 0.584
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.565
Npy2r neuropeptide Y receptor Y2 0.564
Pdx1 pancreatic and duodenal homeobox 1 0.563
Stat5a signal transducer and activator of transcription 5A 0.548
Drd2 dopamine receptor D2 0.540
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.528
Mup5 major urinary protein 5 0.521
Clk1 CDC-like kinase 1 0.512
Mapk14 mitogen-activated protein kinase 14 0.472
Pim1 proviral integration site 1 0.455
Agrp agouti related protein 0.443
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.435
Kiss1r KISS1 receptor 0.434
Grid2 glutamate receptor, ionotropic, delta 2 0.430
Ldha lactate dehydrogenase A 0.420
Kl klotho 0.411
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.408
Ccnl2 cyclin L2 0.398
Prkce protein kinase C, epsilon 0.392
Pnpla2 patatin-like phospholipase domain containing 2 0.392
Thrb thyroid hormone receptor beta 0.387
Per1 period homolog 1 (Drosophila) 0.376
Igf2 insulin-like growth factor 2 0.375
Atxn1 ataxin 1 0.367
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.361
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.361
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.357
Lipe lipase, hormone sensitive 0.355
Mup10 major urinary protein 10 0.354
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.354
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.347
Hnf4a hepatic nuclear factor 4, alpha 0.346
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.344
Gpi1 glucose phosphate isomerase 1 0.343
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.332
Trib3 tribbles homolog 3 (Drosophila) 0.309
T brachyury 0.287
Hif1a hypoxia inducible factor 1, alpha subunit 0.277
Mup4 major urinary protein 4 0.274
Ulk1 Unc-51 like kinase 1 (C. elegans) 0.268
Crhr1 corticotropin releasing hormone receptor 1 0.262
Ccnt2 cyclin T2 0.255
Fgf5 fibroblast growth factor 5 0.252
Fos FBJ osteosarcoma oncogene 0.251
Pomc pro-opiomelanocortin-alpha 0.251
Grb10 growth factor receptor bound protein 10 0.245
Cry1 cryptochrome 1 (photolyase-like) 0.242
Cckbr cholecystokinin B receptor 0.240
Tox thymocyte selection-associated high mobility group box 0.239
Igf1 insulin-like growth factor 1 0.236
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.236
Gck glucokinase 0.231
Lmx1b LIM homeobox transcription factor 1 beta 0.220
Vegfa vascular endothelial growth factor A 0.219
F2 coagulation factor II 0.217
Nfil3 nuclear factor, interleukin 3, regulated 0.215
Dsg4 desmoglein 4 0.215
Igh immunoglobulin heavy chain complex 0.215
Ep300 E1A binding protein p300 0.213
Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 0.213
Otp orthopedia homolog (Drosophila) 0.212
Il9 interleukin 9 0.207
Il7 interleukin 7 0.203
Ambp alpha 1 microglobulin/bikunin 0.200
Bcl2 B-cell leukemia/lymphoma 2 0.199
Mup19 major urinary protein 19 0.197
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.192
Pik3cb phosphatidylinositol 3-kinase, catalytic, beta polypeptide 0.185
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.184
D4Wsu53e DNA segment, Chr 4, Wayne State University 53, expressed 0.183
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.181
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.180
Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.179
Socs1 suppressor of cytokine signaling 1 0.177
Lmx1a LIM homeobox transcription factor 1 alpha 0.176
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ldha lactate dehydrogenase A 0.931
Pkm2 pyruvate kinase, muscle 0.634
Eno1 enolase 1, (alpha) 0.482
Tpi1 triosephosphate isomerase 1 0.482
Gpi glucose phosphate isomerase 0.453
Aldoa aldolase A, fructose-bisphosphate 0.418
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.377
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.268
Dbp D site of albumin promoter (albumin D-box) binding protein 0.189
Pgam1 phosphoglycerate mutase 1 (brain) 0.167
Mif macrophage migration inhibitory factor 0.125
Eef2 eukaryotic translation elongation factor 2 0.122
Igfals insulin-like growth factor binding protein, acid labile subunit 0.122
Ldhd lactate dehydrogenase D 0.117
Pgm1 phosphoglucomutase 1 0.111
Pfkm phosphofructokinase, muscle 0.099
Pgk1 phosphoglycerate kinase 1 0.089
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.087
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.083
Tkt transketolase 0.076
Ly6al lymphocyte antigen 6 complex, locus A-like 0.076
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.074
Serinc1 serine incorporator 1 0.061
Pygm phosphorylase, glycogen, muscle 0.059
Mlxipl MLX interacting protein-like 0.059
Hist1h2ba histone cluster 1, H2ba 0.058
Ccnd3 cyclin D3 0.058
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.057
Ccl3 chemokine (C-C motif) ligand 3 0.056
Ak1 adenylate kinase 1 0.054
Nfia nuclear factor I/A 0.051
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.051
Fitm1 fat storage-inducing transmembrane protein 1 0.049
A1cf APOBEC1 complementation factor 0.048
Met met proto-oncogene 0.048
Acads acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain 0.048
Acot2 acyl-CoA thioesterase 2 0.048
Impdh2 IMP (inosine monophosphate) dehydrogenase 2 0.047
Irs3 insulin receptor substrate 3 0.047
G6pc glucose-6-phosphatase, catalytic subunit 0.047
Ubtf upstream binding transcription factor, RNA polymerase I 0.047
Mosc1 MOCO sulphurase C-terminal domain containing 1 0.047
Gse1 genetic suppressor element 1 0.046
Aldob aldolase B, fructose-bisphosphate 0.046
Casp2 caspase 2 0.044
Faah fatty acid amide hydrolase 0.044
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.043
Il6 interleukin 6 0.043
Rpl3l ribosomal protein L3-like 0.042
Ss18l1 synovial sarcoma translocation gene on chromosome 18-like 1 0.041
Jun Jun oncogene 0.041
Etfdh electron-transferring-flavoprotein dehydrogenase 0.039
Apoa4 apolipoprotein A-IV 0.039
Foxo1 forkhead box O1 0.039
Dck deoxycytidine kinase 0.039
Foxa3 forkhead box A3 0.037
Asph aspartate-beta-hydroxylase 0.037
Gcgr glucagon receptor 0.036
Slc25a42 solute carrier family 25, member 42 0.035
Ptprs protein tyrosine phosphatase, receptor type, S 0.035
Hand2 heart and neural crest derivatives expressed 2 0.035
Espn espin 0.035
Smad3 SMAD family member 3 0.035
Obp3 alpha-2u globulin PGCL4 0.035
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.034
Slc37a4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.033
Dak dihydroxyacetone kinase 2 homolog (S. cerevisiae) 0.032
Ccl20 chemokine (C-C motif) ligand 20 0.032
Hmox1 heme oxygenase (decycling) 1 0.032
Mgat3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.031
Abcb4 ATP-binding cassette, subfamily B (MDR/TAP), member 4 0.031
Aco2 aconitase 2, mitochondrial 0.031
Csk c-src tyrosine kinase 0.031
Lypla1 lysophospholipase 1 0.031
Zadh2 zinc binding alcohol dehydrogenase, domain containing 2 0.030
Macrod1 MACRO domain containing 1 0.030
Nup153 nucleoporin 153 0.030
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.030
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.030
Grinl1a glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A 0.029
Ghr growth hormone receptor 0.029
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.029
Uba3 ubiquitin-like modifier activating enzyme 3 0.029
Btg2 BTG family, member 2 0.029
Ampd1 adenosine monophosphate deaminase 1 (isoform M) 0.029
Rab1b RAB1B, member RAS oncogene family 0.028
Aes amino-terminal enhancer of split 0.028
Mylk2 myosin light chain kinase 2 0.027
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.027
Mgat2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 0.027
RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase 0.027
Syngr2 synaptogyrin 2 0.027
Acot12 acyl-CoA thioesterase 12 0.027
Bmpr1a bone morphogenetic protein receptor, type IA 0.027
Errfi1 ERBB receptor feedback inhibitor 1 0.027
Tubg1 tubulin, gamma 1 0.027
Stat5b signal transducer and activator of transcription 5B 0.027
Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.027
Fut1 fucosyltransferase 1 0.027
Phka1 phosphorylase kinase, alpha 1 0.026