The network for 'cofactor metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cofactor metabolic process

The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
TAL1 Tal1p 0.961
ADH3 Adh3p 0.943
PDB1 Pdb1p 0.919
IDH2 Idh2p 0.898
LSC1 Lsc1p 0.850
ALD6 Ald6p 0.799
MVD1 Mvd1p 0.798
LAT1 Lat1p 0.742
COQ9 Coq9p 0.680
HEM2 Hem2p 0.653
MDH1 Mdh1p 0.650
ACC1 Acc1p 0.636
SIP2 Sip2p 0.572
CAT5 Cat5p 0.549
SOL1 Sol1p 0.543
YJL068C hypothetical protein 0.528
ERG13 Erg13p 0.520
TNA1 Tna1p 0.516
BIO3 Bio3p 0.495
ERG12 Erg12p 0.481
GND2 Gnd2p 0.476
BNA6 Bna6p 0.426
ADE17 Ade17p 0.413
CAB3 Cab3p 0.400
BIO4 Bio4p 0.382
DLD1 Dld1p 0.362
COQ6 Coq6p 0.350
GAL83 Gal83p 0.339
YPR1 Ypr1p 0.337
MAE1 Mae1p 0.332
UTR1 Utr1p 0.331
TFS1 Tfs1p 0.328
LPD1 Lpd1p 0.325
HEM12 Hem12p 0.312
ADE13 Ade13p 0.305
ADE4 Ade4p 0.302
YIH1 Yih1p 0.299
YNL108C hypothetical protein 0.298
NIF3 Nif3p 0.295
YKL077W hypothetical protein 0.291
GLT1 Glt1p 0.279
LEU5 Leu5p 0.272
HXK2 Hxk2p 0.270
MET6 Met6p 0.270
IDH1 Idh1p 0.269
MMP1 Mmp1p 0.265
RNR3 Rnr3p 0.261
TSA2 Tsa2p 0.260
YTP1 Ytp1p 0.247
RBK1 Rbk1p 0.246
WWM1 Wwm1p 0.246
HIS7 His7p 0.243
MET3 Met3p 0.241
YCL042W hypothetical protein 0.239
PDA1 Pda1p 0.237
XKS1 Xks1p 0.235
ECM31 Ecm31p 0.232
OAC1 Oac1p 0.225
CAR2 Car2p 0.225
HEM15 Hem15p 0.219
WTM2 Wtm2p 0.219
LSB6 Lsb6p 0.219
RIB1 Rib1p 0.218
CAB4 Cab4p 0.211
PNC1 Pnc1p 0.211
BIO5 Bio5p 0.208
COA3 Coa3p 0.208
YKR070W hypothetical protein 0.206
APE3 Ape3p 0.205
LEU1 Leu1p 0.204
COQ5 Coq5p 0.203
MPD1 Mpd1p 0.202
PFK1 Pfk1p 0.197
ADH1 Adh1p 0.197
MIR1 Mir1p 0.196
LYS4 Lys4p 0.194
GPM2 Gpm2p 0.194
COQ8 Coq8p 0.192
NFU1 Nfu1p 0.192
SIS2 Sis2p 0.190
SHM2 Shm2p 0.189
BCY1 Bcy1p 0.189
COQ2 Coq2p 0.188
AIM45 Aim45p 0.187
SOL3 Sol3p 0.185
MRI1 Mri1p 0.184
ADH2 Adh2p 0.183
INM2 Inm2p 0.182
MCT1 Mct1p 0.181
TGL5 Tgl5p 0.180
PUS6 Pus6p 0.179
RME1 Rme1p 0.176
ISN1 Isn1p 0.175
CBP3 Cbp3p 0.175
SPE3 Spe3p 0.174
PGM2 Pgm2p 0.173
ACS1 Acs1p 0.173
TKL2 Tkl2p 0.171
KGD2 Kgd2p 0.170
POA1 Poa1p 0.169
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
cyp-35A2 Protein CYP-35A2 0.137
ugt-22 Protein UGT-22 0.087
cyp-35A3 Protein CYP-35A3 0.047
C34C12.8 Protein C34C12.8 0.046
cyp-35A4 Protein CYP-35A4 0.042
cyp-35C1 Protein CYP-35C1 0.040
CELE_C08H9.2 Protein C08H9.2 0.038
CELE_F59C6.5 Protein F59C6.5 0.033
nstp-2 Protein NSTP-2 0.032
F39B2.3 Protein F39B2.3 0.030
rpn-1 Protein RPN-1 0.030
mthf-1 Protein MTHF-1 0.026
CELE_C29F7.2 Protein C29F7.2 0.026
F13H6.3 Protein F13H6.3 0.025
acl-6 Protein ACL-6 0.021
dlst-1 Protein DLST-1 0.020
R07H5.8 Protein R07H5.8 0.019
mel-32 Protein MEL-32 0.019
metr-1 Protein METR-1 0.019
pccb-1 Protein PCCB-1 0.017
tsfm-1 Protein TSFM-1 0.016
ceeh-2 Protein CEEH-2 0.016
gsp-1 Protein GSP-1 0.016
rpia-1 Protein RPIA-1 0.014
C05C10.3 Protein C05C10.3 0.014
T28H10.3 Protein T28H10.3 0.013
haf-3 Protein HAF-3 0.013
cyp-35A5 Protein CYP-35A5 0.013
K02D10.1 Protein K02D10.1 0.012
tsn-1 Protein TSN-1 0.012
CELE_Y75B8A.4 Protein Y75B8A.4 0.012
C34B2.6 Protein C34B2.6 0.011
dld-1 Protein DLD-1 0.011
F53F1.2 Protein F53F1.2 0.011
clk-1 Protein CLK-1 0.011
C34C6.4 Protein C34C6.4 0.011
F55A4.8 Protein F55A4.8 0.011
elt-7 Protein ELT-7 0.011
sptl-1 Protein SPTL-1 0.011
F58A6.1 Protein F58A6.1 0.011
ZK265.9 Protein ZK265.9 0.011
nft-1 Protein NFT-1 0.010
ZK370.8 Protein ZK370.8 0.010
T06D8.5 Protein T06D8.5 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
alas2 aminolevulinate, delta-, synthetase 2 0.351
epb41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 0.343
tfr1a transferrin receptor 1a 0.271
uros uroporphyrinogen III synthase 0.247
slc4a2b solute carrier family 4, anion exchanger, member 2b 0.235
urod uroporphyrinogen decarboxylase 0.210
brp44 brain protein 44 0.200
aldh7a1 aldehyde dehydrogenase 7 family, member A1 0.197
prdx2 peroxiredoxin 2 0.136
aco1 aconitase 1, soluble 0.132
chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.122
pawrl PRKC, apoptosis, WT1, regulator like 0.087
fech ferrochelatase 0.077
mvp major vault protein 0.073
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.067
lap3 leucine aminopeptidase 3 0.066
pgd phosphogluconate hydrogenase 0.061
selt1a selenoprotein T, 1a 0.049
zgc:64042 zgc:64042 0.047
klfd Kruppel-like factor d 0.046
gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 0.046
glrx glutaredoxin (thioltransferase) 0.042
ucp2 uncoupling protein 2 0.039
cd63 Cd63 antigen 0.037
hbae1 hemoglobin alpha embryonic-1 0.035
slc12a3 solute carrier family 12 (sodium/chloride transporters), member 3 0.035
blvrb biliverdin reductase B (flavin reductase (NADPH)) 0.034
pccb propionyl Coenzyme A carboxylase, beta polypeptide 0.034
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.034
ddt D-dopachrome tautomerase 0.033
echdc2 enoyl CoA hydratase domain containing 2 0.031
sod2 superoxide dismutase 2, mitochondrial 0.031
tyms thymidylate synthase 0.030
cldn7b claudin 7b 0.030
capn2b calpain 2, (m/II) large subunit b 0.030
hspd1 heat shock 60kD protein 1 (chaperonin) 0.029
gata1a GATA binding protein 1a 0.029
dera 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) 0.028
sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.028
aco2 aconitase 2, mitochondrial 0.027
cbr1l carbonyl reductase 1-like 0.026
zgc:101723 zgc:101723 0.026
hadh hydroxyacyl-Coenzyme A dehydrogenase 0.026
mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 0.025
cldnf claudin f 0.025
iba57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 0.025
idh3a isocitrate dehydrogenase 3 (NAD+) alpha 0.024
ppox protoporphyrinogen oxidase 0.024
tspo translocator protein 0.024
impdh2 IMP (inosine monophosphate) dehydrogenase 2 0.024
acvr2a activin receptor IIa 0.023
mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.023
glrx5 glutaredoxin 5 homolog (S. cerevisiae) 0.022
ndufa8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 0.022
sucla2 succinate-CoA ligase, ADP-forming, beta subunit 0.022
zgc:92745 zgc:92745 0.022
ctage5 CTAGE family, member 5 0.022
si:ch211-160j6.2 si:ch211-160j6.2 0.021
arrdc1a arrestin domain containing 1a 0.021
adka adenosine kinase a 0.021
ctsz cathepsin Z 0.021
prdx3 peroxiredoxin 3 0.021
zgc:73293 zgc:73293 0.021
ctsd cathepsin D 0.020
ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase 0.020
tufm Tu translation elongation factor, mitochondrial 0.020
glulb glutamate-ammonia ligase (glutamine synthase) b 0.020
hbbe3 hemoglobin beta embryonic-3 0.020
bpnt1 bisphosphate nucleotidase 1 0.019
bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide 0.019
bdh2 3-hydroxybutyrate dehydrogenase, type 2 0.019
ivns1abpa influenza virus NS1A binding protein a 0.018
ndufb6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 0.018
zgc:162943 zgc:162943 0.018
cox17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) 0.017
atp7a ATPase, Cu++ transporting, alpha polypeptide 0.017
zgc:55813 zgc:55813 0.017
nccrp1 nonspecific cytotoxic cell receptor protein 1 0.017
ctsl1a cathepsin L, 1 a 0.017
zgc:92903 zgc:92903 0.017
zgc:86841 zgc:86841 0.016
alad aminolevulinate dehydratase 0.016
zgc:73273 zgc:73273 0.016
prkab1b protein kinase, AMP-activated, beta 1 non-catalytic subunit, b 0.016
phyhd1 phytanoyl-CoA dioxygenase domain containing 1 0.016
serpinb1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.016
hmbsb hydroxymethylbilane synthase, b 0.015
dhdhl dihydrodiol dehydrogenase (dimeric), like 0.015
zgc:198195 zgc:198195 0.015
cyc1 cytochrome c-1 0.015
dldh dihydrolipoamide dehydrogenase 0.015
zgc:101724 zgc:101724 0.015
slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.015
hbbe2 hemoglobin beta embryonic-2 0.015
tmem184a transmembrane protein 184a 0.015
ireb2 iron-responsive element binding protein 2 0.015
upb1 ureidopropionase, beta 0.015
sccpdhb saccharopine dehydrogenase b 0.015
zgc:73311 zgc:73311 0.014
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.014
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
PyK Pyruvate kinase 0.034
Got2 Glutamate oxaloacetate transaminase 2 0.032
Pgd Phosphogluconate dehydrogenase 0.014
Lsd-1 Lipid storage droplet-1 0.014
CG3902 CG3902 gene product from transcript CG3902-RA 0.012
CG9510 CG9510 gene product from transcript CG9510-RC 0.012
Eno Enolase 0.011
CG7920 CG7920 gene product from transcript CG7920-RA 0.011
CG11089 CG11089 gene product from transcript CG11089-RD 0.011
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SPTB spectrin, beta, erythrocytic 0.996
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.993
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.993
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.977
PDHX pyruvate dehydrogenase complex, component X 0.965
TKT transketolase 0.953
PDHB pyruvate dehydrogenase (lipoamide) beta 0.952
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.941
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.941
DLAT dihydrolipoamide S-acetyltransferase 0.926
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.879
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.877
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.860
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.849
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.841
HADH hydroxyacyl-CoA dehydrogenase 0.780
UROD uroporphyrinogen decarboxylase 0.749
GRHPR glyoxylate reductase/hydroxypyruvate reductase 0.721
ACAT1 acetyl-CoA acetyltransferase 1 0.720
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.692
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.668
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.665
TST thiosulfate sulfurtransferase (rhodanese) 0.654
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.648
SPTA1 spectrin, alpha, erythrocytic 1 (elliptocytosis 2) 0.647
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.636
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.626
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.609
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.582
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.551
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.544
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.501
TJP1 tight junction protein 1 (zona occludens 1) 0.493
TALDO1 transaldolase 1 0.486
ENO1 enolase 1, (alpha) 0.461
LYRM7 Lyrm7 homolog (mouse) 0.460
ETFDH electron-transferring-flavoprotein dehydrogenase 0.458
ANK1 ankyrin 1, erythrocytic 0.454
CPT2 carnitine palmitoyltransferase 2 0.452
TYMS thymidylate synthetase 0.436
ECI1 enoyl-CoA delta isomerase 1 0.420
APEH N-acylaminoacyl-peptide hydrolase 0.406
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.367
ARRB1 arrestin, beta 1 0.338
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.335
SLC4A1 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) 0.324
AGXT2 alanine--glyoxylate aminotransferase 2 0.322
PROX1 prospero homeobox 1 0.319
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 0.302
MUT methylmalonyl CoA mutase 0.299
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.295
PEX7 peroxisomal biogenesis factor 7 0.294
ACAA1 acetyl-CoA acyltransferase 1 0.293
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.291
ERP29 endoplasmic reticulum protein 29 0.288
EBP emopamil binding protein (sterol isomerase) 0.285
FBXL15 F-box and leucine-rich repeat protein 15 0.281
GLA galactosidase, alpha 0.276
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.273
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.270
QARS glutaminyl-tRNA synthetase 0.265
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.262
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.261
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.257
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.255
AGPS alkylglycerone phosphate synthase 0.254
SCP2 sterol carrier protein 2 0.254
HSPB1 heat shock 27kDa protein 1 0.252
FH fumarate hydratase 0.251
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.243
APRT adenine phosphoribosyltransferase 0.237
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.233
ACADSB acyl-CoA dehydrogenase, short/branched chain 0.231
MME membrane metallo-endopeptidase 0.230
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.229
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.218
CDK2 cyclin-dependent kinase 2 0.215
ANKRD13A ankyrin repeat domain 13A 0.213
FAF1 Fas (TNFRSF6) associated factor 1 0.211
BBS1 Bardet-Biedl syndrome 1 0.211
ISOC1 isochorismatase domain containing 1 0.204
ZFYVE9 zinc finger, FYVE domain containing 9 0.202
KIAA0101 KIAA0101 0.201
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.201
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.198
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 0.198
G6PD glucose-6-phosphate dehydrogenase 0.196
ETFB electron-transfer-flavoprotein, beta polypeptide 0.192
PGD phosphogluconate dehydrogenase 0.189
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) 0.189
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.186
ZHX1 zinc fingers and homeoboxes 1 0.182
GSS glutathione synthetase 0.180
CAT catalase 0.174
HSDL2 hydroxysteroid dehydrogenase like 2 0.174
AK2 adenylate kinase 2 0.171
SLC30A9 solute carrier family 30 (zinc transporter), member 9 0.168
CDT1 chromatin licensing and DNA replication factor 1 0.167
SMAD1 SMAD family member 1 0.166
MAPT microtubule-associated protein tau 0.166
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Spna1 spectrin alpha 1 0.991
Exoc6 exocyst complex component 6 0.973
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.954
Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 0.928
Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.926
Eci2 enoyl-Coenzyme A delta isomerase 2 0.853
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.839
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.824
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.816
Hadh hydroxyacyl-Coenzyme A dehydrogenase 0.801
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.790
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.766
Acot9 acyl-CoA thioesterase 9 0.748
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.723
Hbb-b1 hemoglobin, beta adult major chain 0.719
Acot10 acyl-CoA thioesterase 10 0.718
Gsta3 glutathione S-transferase, alpha 3 0.706
G6pc glucose-6-phosphatase, catalytic 0.650
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.650
Tat tyrosine aminotransferase 0.648
Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 0.635
Vdac2 voltage-dependent anion channel 2 0.617
Inmt indolethylamine N-methyltransferase 0.597
Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.593
Akr1c6 aldo-keto reductase family 1, member C6 0.581
Fmo1 flavin containing monooxygenase 1 0.568
Cps1 carbamoyl-phosphate synthetase 1 0.558
Hbb-b2 hemoglobin, beta adult minor chain 0.548
Retsat retinol saturase (all trans retinol 13,14 reductase) 0.545
Ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.541
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.538
Pnp2 purine-nucleoside phosphorylase 2 0.523
Gsta2 glutathione S-transferase, alpha 2 (Yc2) 0.523
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.520
Taldo1 transaldolase 1 0.519
Pgd phosphogluconate dehydrogenase 0.499
Hrg histidine-rich glycoprotein 0.493
Gstm3 glutathione S-transferase, mu 3 0.491
Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 0.490
Cat catalase 0.490
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.482
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.479
Azgp1 alpha-2-glycoprotein 1, zinc 0.465
Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 0.462
Cyp4a31 cytochrome P450, family 4, subfamily a, polypeptide 31 0.443
Acsl1 acyl-CoA synthetase long-chain family member 1 0.439
Ces1d carboxylesterase 1D 0.415
Aadac arylacetamide deacetylase (esterase) 0.415
Sdhd succinate dehydrogenase complex, subunit D, integral membrane protein 0.411
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.406
Nr1i3 nuclear receptor subfamily 1, group I, member 3 0.393
Pccb propionyl Coenzyme A carboxylase, beta polypeptide 0.386
Gstm1 glutathione S-transferase, mu 1 0.385
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.374
F13b coagulation factor XIII, beta subunit 0.372
Adh1 alcohol dehydrogenase 1 (class I) 0.371
Hba-a2 hemoglobin alpha, adult chain 2 0.371
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.368
D10Jhu81e DNA segment, Chr 10, Johns Hopkins University 81 expressed 0.368
Ank1 ankyrin 1, erythroid 0.362
Etfa electron transferring flavoprotein, alpha polypeptide 0.361
Fam73b family with sequence similarity 73, member B 0.360
Klf1 Kruppel-like factor 1 (erythroid) 0.357
Dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.338
Gstk1 glutathione S-transferase kappa 1 0.335
Pon1 paraoxonase 1 0.333
Vnn3 vanin 3 0.332
Hmbs hydroxymethylbilane synthase 0.331
Epb4.1 erythrocyte protein band 4.1 0.329
Acot12 acyl-CoA thioesterase 12 0.324
Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 0.323
Hagh hydroxyacyl glutathione hydrolase 0.323
Dhrs4 dehydrogenase/reductase (SDR family) member 4 0.310
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.302
Acot1 acyl-CoA thioesterase 1 0.295
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.294
Pklr pyruvate kinase liver and red blood cell 0.291
Spnb1 spectrin beta 1 0.290
Ech1 enoyl coenzyme A hydratase 1, peroxisomal 0.286
Keg1 kidney expressed gene 1 0.285
Tdo2 tryptophan 2,3-dioxygenase 0.280
Fmo5 flavin containing monooxygenase 5 0.279
Idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.279
Hint2 histidine triad nucleotide binding protein 2 0.276
Pcx pyruvate carboxylase 0.271
Timd2 T-cell immunoglobulin and mucin domain containing 2 0.270
Gjb1 gap junction protein, beta 1 0.268
Acaa1b acetyl-Coenzyme A acyltransferase 1B 0.265
Dmgdh dimethylglycine dehydrogenase precursor 0.262
Sord sorbitol dehydrogenase 0.261
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.259
Add2 adducin 2 (beta) 0.258
Mat1a methionine adenosyltransferase I, alpha 0.257
F9 coagulation factor IX 0.254
Hsd3b4 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 0.252
Ces1g carboxylesterase 1G 0.251
Gsta4 glutathione S-transferase, alpha 4 0.244
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.243
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.240
Clybl citrate lyase beta like 0.240
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.992
Fasn fatty acid synthase 0.928
Sc4mol sterol-C4-methyl oxidase-like 0.891
Idi1 isopentenyl-diphosphate delta isomerase 1 0.861
Dhcr7 7-dehydrocholesterol reductase 0.751
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.724
Slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.712
Pgk1 phosphoglycerate kinase 1 0.707
Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.660
Nit2 nitrilase family, member 2 0.652
Sardh sarcosine dehydrogenase 0.638
Tkt transketolase 0.629
Hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit 0.625
Trap1 TNF receptor-associated protein 1 0.618
Glud1 glutamate dehydrogenase 1 0.615
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.600
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.595
Aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.575
Fh1 fumarate hydratase 1 0.533
Srebf1 sterol regulatory element binding transcription factor 1 0.453
Cyp51 cytochrome P450, family 51 0.432
LOC100363662 6-phosphogluconate dehydrogenase, decarboxylating-like 0.429
Acat3 acetyl-Coenzyme A acetyltransferase 3 0.424
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.390
Tufm Tu translation elongation factor, mitochondrial 0.386
Aldh7a1 aldehyde dehydrogenase 7 family, member A1 0.383
Pkm2 pyruvate kinase, muscle 0.372
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.372
Dld dihydrolipoamide dehydrogenase 0.370
Mccc2 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) 0.365
Ddt D-dopachrome tautomerase 0.363
Acads acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain 0.362
Acaca acetyl-coenzyme A carboxylase alpha 0.350
Fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) 0.334
Fmo3 flavin containing monooxygenase 3 0.334
Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.326
Tst thiosulfate sulfurtransferase 0.324
Dpys dihydropyrimidinase 0.322
Idh3B isocitrate dehydrogenase 3 (NAD+) beta 0.321
Got1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 0.318
Mipep mitochondrial intermediate peptidase 0.302
Aco2 aconitase 2, mitochondrial 0.300
Alad aminolevulinate, delta-, dehydratase 0.300
Bckdhb branched chain keto acid dehydrogenase E1, beta polypeptide 0.297
LOC293989 cytochrome P450-like 0.293
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.280
Fdft1 farnesyl diphosphate farnesyl transferase 1 0.276
Atp5f1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 0.273
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.273
Uqcrc2 ubiquinol cytochrome c reductase core protein 2 0.272
Grhpr glyoxylate reductase/hydroxypyruvate reductase 0.271
Mosc2 MOCO sulphurase C-terminal domain containing 2 0.271
Urod uroporphyrinogen decarboxylase 0.263
Suclg1 succinate-CoA ligase, alpha subunit 0.249
Slc25a10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 0.247
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.239
Spp2 secreted phosphoprotein 2 0.234
Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 0.230
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.218
Fbp1 fructose-1,6-bisphosphatase 1 0.218
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.211
Acox2 acyl-Coenzyme A oxidase 2, branched chain 0.210
Apeh N-acylaminoacyl-peptide hydrolase 0.209
Dmgdh dimethylglycine dehydrogenase 0.209
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.200
Auh AU RNA binding protein/enoyl-coenzyme A hydratase 0.198
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.197
Suclg2 succinate-CoA ligase, GDP-forming, beta subunit 0.192
Tpi1 triosephosphate isomerase 1 0.190
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.188
Aldh9a1 aldehyde dehydrogenase 9 family, member A1 0.187
Aldh4a1 aldehyde dehydrogenase 4 family, member A1 0.184
Mosc1 MOCO sulphurase C-terminal domain containing 1 0.181
Pdha1 pyruvate dehydrogenase (lipoamide) alpha 1 0.172
Aadac arylacetamide deacetylase (esterase) 0.171
Ccs copper chaperone for superoxide dismutase 0.170
Sdhd succinate dehydrogenase complex, subunit D, integral membrane protein 0.170
Ghitm growth hormone inducible transmembrane protein 0.170
Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.169
Slc25a1 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 0.169
Pcyt2 phosphate cytidylyltransferase 2, ethanolamine 0.166
Sord sorbitol dehydrogenase 0.162
Ahcy adenosylhomocysteinase 0.157
Cyc1 cytochrome c-1 0.156
Acacb acetyl-Coenzyme A carboxylase beta 0.156
Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 0.152
Eci1 enoyl-Coenzyme A delta isomerase 1 0.150
Prdx6 peroxiredoxin 6 0.141
Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.141
Aqp9 aquaporin 9 0.138
Mbl1 mannose-binding lectin (protein A) 1 0.137
Ech1 enoyl coenzyme A hydratase 1, peroxisomal 0.135
Dhcr24 24-dehydrocholesterol reductase 0.130
Vdac2 voltage-dependent anion channel 2 0.127
Isca1 iron-sulfur cluster assembly 1 homolog (S. cerevisiae) 0.127
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.125
Hmbs hydroxymethylbilane synthase 0.124
Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 0.124
Hagh hydroxyacyl glutathione hydrolase 0.122
Gcdh glutaryl-Coenzyme A dehydrogenase 0.121