The network for 'nuclear mrna surveillance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nuclear mrna surveillance

The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RRP6 Rrp6p 0.992
NRD1 Nrd1p 0.944
AIR2 Air2p 0.939
PAP2 Pap2p 0.934
MPP6 Mpp6p 0.736
THP2 Thp2p 0.711
AIR1 Air1p 0.665
LRP1 Lrp1p 0.573
RRP45 Rrp45p 0.465
NUP60 Nup60p 0.447
RRP43 Rrp43p 0.433
RRP46 Rrp46p 0.419
GBP2 Gbp2p 0.419
HPR1 Hpr1p 0.366
NAB3 Nab3p 0.355
DIS3 Dis3p 0.251
THO2 Tho2p 0.234
MEX67 Mex67p 0.209
RAT1 Rat1p 0.195
SUB2 Sub2p 0.185
SKI6 Ski6p 0.176
MTR4 Mtr4p 0.160
NOP53 Nop53p 0.122
MLP2 Mlp2p 0.115
STO1 Sto1p 0.115
MTR3 Mtr3p 0.094
SUS1 Sus1p 0.080
RRP40 Rrp40p 0.069
SKI7 Ski7p 0.069
THG1 Thg1p 0.069
TRA1 Tra1p 0.066
HRP1 Hrp1p 0.062
CSL4 Csl4p 0.060
SWT1 Swt1p 0.058
HRB1 Hrb1p 0.051
SKI3 Ski3p 0.051
KEM1 Kem1p 0.051
SRD1 Srd1p 0.048
GLE2 Gle2p 0.047
SPT5 Spt5p 0.047
SEN1 Sen1p 0.047
ARG8 Arg8p 0.046
YLR264C-A hypothetical protein 0.044
YIR035C hypothetical protein 0.043
RIO1 Rio1p 0.042
URA3 Ura3p 0.042
ARP10 Arp10p 0.041
LEU2 Leu2p 0.040
YLR162W hypothetical protein 0.037
RRP15 Rrp15p 0.037
DED1 Ded1p 0.036
MER1 Mer1p 0.035
YOL038C-A hypothetical protein 0.035
YAR068W hypothetical protein 0.031
CRP1 Crp1p 0.031
IXR1 Ixr1p 0.031
HXT3 Hxt3p 0.030
SPL2 Spl2p 0.030
HO Hop 0.029
BSC1 Bsc1p 0.029
ATP6 Atp6p 0.028
FMT1 Fmt1p 0.028
BRN1 Brn1p 0.027
YLR042C hypothetical protein 0.027
YPR157W hypothetical protein 0.027
SWC7 Swc7p 0.027
HPF1 Hpf1p 0.026
REV1 Rev1p 0.025
NUT2 Nut2p 0.023
PUS9 Pus9p 0.023
YBR013C hypothetical protein 0.023
SWI1 Swi1p 0.022
SRP101 Srp101p 0.022
AUA1 Aua1p 0.022
ZPS1 Zps1p 0.022
YPR096C hypothetical protein 0.022
CUP1-1 Cup1-1p 0.022
YIL151C hypothetical protein 0.021
SCM4 Scm4p 0.021
MF(ALPHA)2 Mf(alpha)2p 0.021
TIF4632 Tif4632p 0.021
ADH2 Adh2p 0.021
PTI1 Pti1p 0.021
MFT1 Mft1p 0.020
RRN5 Rrn5p 0.020
YOL013W-A hypothetical protein 0.020
TYE7 Tye7p 0.020
CPD1 Cpd1p 0.020
YAR066W hypothetical protein 0.020
ALT2 Alt2p 0.020
YJL107C hypothetical protein 0.020
NGL2 Ngl2p 0.020
MCM6 Mcm6p 0.019
TRI1 Tri1p 0.019
AGE1 Age1p 0.019
MAK10 Mak10p 0.019
DIC1 Dic1p 0.019
NOP8 Nop8p 0.018
YAL037C-A hypothetical protein 0.018
IZH4 Izh4p 0.018
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
EXOSC3 exosome component 3 0.995
DIS3L DIS3 mitotic control homolog (S. cerevisiae)-like 0.636
EXOSC7 exosome component 7 0.435
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.356
EXOSC2 exosome component 2 0.316
EIF4A3 eukaryotic translation initiation factor 4A3 0.177
EXOSC9 exosome component 9 0.161
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.112
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.097
PRPF38A PRP38 pre-mRNA processing factor 38 (yeast) domain containing A 0.089
SRSF2 serine/arginine-rich splicing factor 2 0.074
YBX1 Y box binding protein 1 0.066
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.063
DIS3 DIS3 mitotic control homolog (S. cerevisiae) 0.042
RBMX RNA binding motif protein, X-linked 0.035
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.035
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.033
SRSF7 serine/arginine-rich splicing factor 7 0.031
EXOSC8 exosome component 8 0.029
RBM8A RNA binding motif protein 8A 0.028
ERH enhancer of rudimentary homolog (Drosophila) 0.026
EXOSC1 exosome component 1 0.025
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.024
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 0.020
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.018
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.017
NCL nucleolin 0.017
MPHOSPH6 M-phase phosphoprotein 6 0.016
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.015
EXOSC4 exosome component 4 0.012
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.012
THOC4 THO complex 4 0.011
SRSF3 serine/arginine-rich splicing factor 3 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.099
Hnrnpm heterogeneous nuclear ribonucleoprotein M 0.062
Hdac2 histone deacetylase 2 0.061
Anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.054
Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 0.045
Srsf3 serine/arginine-rich splicing factor 3 0.041
Ptges3 prostaglandin E synthase 3 (cytosolic) 0.038
Ncbp2 nuclear cap binding protein subunit 2 0.033
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.031
Nap1l1 nucleosome assembly protein 1-like 1 0.025
Kpnb1 karyopherin (importin) beta 1 0.024
Actl6a actin-like 6A 0.023
Tardbp TAR DNA binding protein 0.022
Dcaf13 DDB1 and CUL4 associated factor 13 0.022
Srsf10 serine/arginine-rich splicing factor 10 0.019
Ilf2 interleukin enhancer binding factor 2 0.019
Hmgb1 high mobility group box 1 0.018
Set SET nuclear oncogene 0.018
Srsf2 serine/arginine-rich splicing factor 2 0.017
Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 0.017
Thoc4 THO complex 4 0.017
Xpo1 exportin 1, CRM1 homolog (yeast) 0.016
Serbp1 serpine1 mRNA binding protein 1 0.015
2500003M10Rik RIKEN cDNA 2500003M10 gene 0.014
Srsf7 serine/arginine-rich splicing factor 7 0.013
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.013
Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 0.012
Hnrnpd heterogeneous nuclear ribonucleoprotein D 0.012
Rbm8a RNA binding motif protein 8a 0.012
Nono non-POU-domain-containing, octamer binding protein 0.011
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.011
Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 0.011
Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 0.010
Hnrnpu heterogeneous nuclear ribonucleoprotein U 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism