The network for 'protein acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein acetylation

The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.

Name Description Probability Func Analog Organism
ADA2 Ada2p 1.000
TRA1 Tra1p 1.000
HHT1 Hht1p 0.998
TAF6 Taf6p 0.998
NGG1 Ngg1p 0.991
SPT8 Spt8p 0.982
GCN5 Gcn5p 0.975
SUS1 Sus1p 0.947
HFI1 Hfi1p 0.946
TAF12 Taf12p 0.893
TAF10 Taf10p 0.869
YAF9 Yaf9p 0.868
SPT7 Spt7p 0.848
SGF29 Sgf29p 0.842
EAF1 Eaf1p 0.803
SPT20 Spt20p 0.739
TAF9 Taf9p 0.704
SGF11 Sgf11p 0.694
TAF5 Taf5p 0.669
MAK10 Mak10p 0.623
EPL1 Epl1p 0.609
EAF6 Eaf6p 0.609
YNG1 Yng1p 0.592
ARP4 Arp4p 0.591
BDF1 Bdf1p 0.521
ISW1 Isw1p 0.481
ASF1 Asf1p 0.480
RTT106 Rtt106p 0.468
RCO1 Rco1p 0.423
MAK31 Mak31p 0.396
EAF5 Eaf5p 0.386
HAT1 Hat1p 0.352
HAT2 Hat2p 0.290
HHT2 Hht2p 0.254
UBP8 Ubp8p 0.247
RSC2 Rsc2p 0.239
TAF3 Taf3p 0.233
RSC4 Rsc4p 0.219
SPT15 Spt15p 0.217
CKB1 Ckb1p 0.213
HIF1 Hif1p 0.206
CAC2 Cac2p 0.199
MAK3 Mak3p 0.196
SPT3 Spt3p 0.195
SWI1 Swi1p 0.188
SGF73 Sgf73p 0.181
RPD3 Rpd3p 0.178
YNG2 Yng2p 0.165
NTO1 Nto1p 0.157
EAF3 Eaf3p 0.151
TAF14 Taf14p 0.133
RFC5 Rfc5p 0.132
RTT109 Rtt109p 0.131
SWC4 Swc4p 0.126
SNF5 Snf5p 0.125
ESA1 Esa1p 0.117
SAS5 Sas5p 0.116
YAT1 Yat1p 0.114
ORC4 Orc4p 0.114
EAF7 Eaf7p 0.113
HIR2 Hir2p 0.113
HIR1 Hir1p 0.110
MOT1 Mot1p 0.104
TEC1 Tec1p 0.100
SWI5 Swi5p 0.099
SDC1 Sdc1p 0.092
SWD3 Swd3p 0.091
HHO1 Hho1p 0.090
YLR455W hypothetical protein 0.085
BDF2 Bdf2p 0.077
SET2 Set2p 0.076
VPS75 Vps75p 0.075
ELP4 Elp4p 0.073
HHF2 Hhf2p 0.069
RLF2 Rlf2p 0.068
MSB1 Msb1p 0.067
KEM1 Kem1p 0.065
RSC30 Rsc30p 0.062
PFD1 Pfd1p 0.058
ORC3 Orc3p 0.057
IKI1 Iki1p 0.057
NOP10 Nop10p 0.056
TAF13 Taf13p 0.053
YHB1 Yhb1p 0.052
ARP8 Arp8p 0.052
CTF8 Ctf8p 0.051
HDA2 Hda2p 0.050
HPC2 Hpc2p 0.049
LEO1 Leo1p 0.049
DCC1 Dcc1p 0.049
YIR035C hypothetical protein 0.048
SAS3 Sas3p 0.048
RPT6 Rpt6p 0.047
ELP6 Elp6p 0.047
MED1 Med1p 0.046
SWI3 Swi3p 0.046
ORC1 Orc1p 0.044
SUV3 Suv3p 0.044
NSA1 Nsa1p 0.043
SWC5 Swc5p 0.043
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
hat1 histone acetyltransferase 1 0.586
mcmbp minichromosome maintenance complex binding protein 0.408
cse1l chromosome segregation 1-like (S. cerevisiae) 0.396
ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.375
myog myogenin 0.336
ep300b E1A binding protein p300 b 0.324
zc4h2 zinc finger, C4H2 domain containing 0.311
mcrs1 microspherule protein 1 0.299
nasp nuclear autoantigenic sperm protein (histone-binding) 0.293
ube2i ubiquitin-conjugating enzyme E2I 0.274
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.236
hcfc1a host cell factor C1a 0.213
pola1 polymerase (DNA directed), alpha 1 0.200
rbb4 retinoblastoma binding protein 4 0.199
rpa1 replication protein A1 0.199
fen1 flap structure-specific endonuclease 1 0.198
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.192
gtf2f2a general transcription factor IIF, polypeptide 2a 0.187
rpa2 replication protein A2 0.185
anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.184
phf16 PHD finger protein 16 0.168
nktr natural killer-tumor recognition sequence 0.162
mta2 metastasis associated 1 family, member 2 0.160
hirip3 HIRA interacting protein 3 0.154
ipo9 importin 9 0.153
rnf2 ring finger protein 2 0.146
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.142
tal1 T-cell acute lymphocytic leukemia 1 0.141
ccnt2b cyclin T2b 0.141
pom121 POM121 membrane glycoprotein (rat) 0.140
hdac1 histone deacetylase 1 0.139
prmt5 protein arginine methyltransferase 5 0.138
cuedc2 CUE domain containing 2 0.136
usp1 ubiquitin specific protease 1 0.136
cops2 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) 0.132
suv420h2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.131
ss18 synovial sarcoma translocation, chromosome 18 (H. sapiens) 0.128
myf5 myogenic factor 5 0.128
ppm1d protein phosphatase 1D magnesium-dependent, delta isoform 0.127
lztfl1 leucine zipper transcription factor-like 1 0.124
morf4l1 mortality factor 4 like 1 0.124
si:dkey-145p14.5 si:dkey-145p14.5 0.124
phf6 PHD finger protein 6 0.120
pcdh2ac protocadherin 2 alpha c 0.120
crestin crestin 0.119
nop58 NOP58 ribonucleoprotein homolog (yeast) 0.115
brd3a bromodomain containing 3a 0.114
wu:fq41a10 wu:fq41a10 0.112
zgc:73345 zgc:73345 0.110
zgc:172056 zgc:172056 0.110
dcaf7 ddb1 and cul4 associated factor 7 0.109
mycl1a v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) a 0.109
lima1 LIM domain and actin binding 1 0.108
rbb4l retinoblastoma binding protein 4, like 0.108
uba3 ubiquitin-like modifier activating enzyme 3 0.107
apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.107
ube2nb ubiquitin-conjugating enzyme E2Nb 0.105
prp19 PRP19/PSO4 homolog (S. cerevisiae) 0.104
pbrm1l polybromo 1, like 0.104
dedd1 death effector domain-containing 1 0.103
mpped2 metallophosphoesterase domain containing 2 0.102
gle1 GLE1 RNA export mediator homolog (yeast) 0.102
zc3h13 zinc finger CCCH-type containing 13 0.101
tbp TATA box binding protein 0.101
rad51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.100
mcm7 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.098
prdm2b PR domain containing 2, with ZNF domain b 0.097
zgc:114097 zgc:114097 0.096
mpx myeloid-specific peroxidase 0.096
cpsf3 cleavage and polyadenylation specific factor 3 0.096
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.094
taf1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.093
rag1 recombination activating gene 1 0.093
lars leucyl-tRNA synthetase 0.092
hmgb3a high-mobility group box 3a 0.091
zgc:100817 zgc:100817 0.090
bsg basigin 0.089
eif3ja eukaryotic translation initiation factor 3, subunit Ja 0.089
zgc:65861 zgc:65861 0.089
cops3 COP9 constitutive photomorphogenic homolog subunit 3 0.088
hp1bp3 heterochromatin protein 1, binding protein 3 0.088
chek1 CHK1 checkpoint homolog (S. pombe) 0.088
zgc:112083 zgc:112083 0.087
uck2b uridine-cytidine kinase 2b 0.087
rif1 RAP1 interacting factor homolog (yeast) 0.087
zgc:77155 zgc:77155 0.086
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.086
tnpo3 transportin 3 0.085
LOC100534742 UBX domain-containing protein 1-like 0.085
supv3l1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.085
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.085
ankra2 ankyrin repeat, family A (RFXANK-like), 2 0.084
gins2 GINS complex subunit 2 0.084
cbx2 chromobox homolog 2 (Drosophila Pc class) 0.084
kdm1a lysine (K)-specific demethylase 1a 0.084
ilf2 interleukin enhancer binding factor 2 0.083
macf1 microtubule-actin crosslinking factor 1 0.083
med4 mediator complex subunit 4 0.082
mknk2b MAP kinase-interacting serine/threonine kinase 2b 0.082
uba2 ubiquitin-like modifier activating enzyme 2 0.082
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
dik diskette 1.000
CG10414 CG10414 gene product from transcript CG10414-RA 0.999
Hcf Host cell factor 0.983
D12 CG13400 gene product from transcript CG13400-RA 0.981
Snr1 Snf5-related 1 0.968
Mocs2 Molybdopterin synthase 2 0.931
wds will die slowly 0.914
dco discs overgrown 0.889
Pcaf CG4107 gene product from transcript CG4107-RA 0.858
Atac1 ATAC component 1 0.850
Sir2 CG5216 gene product from transcript CG5216-RA 0.815
CTCF CG8591 gene product from transcript CG8591-RA 0.763
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.678
brm brahma 0.670
CG3363 CG3363 gene product from transcript CG3363-RB 0.619
mof males absent on the first 0.618
ash1 absent, small, or homeotic discs 1 0.618
CG13298 CG13298 gene product from transcript CG13298-RA 0.602
Sgf29 CG30390 gene product from transcript CG30390-RA 0.592
His2Av Histone H2A variant 0.577
msl-3 male-specific lethal 3 0.574
pan pangolin 0.572
Saf6 SAGA factor-like TAF6 0.566
Su(var)3-3 Suppressor of variegation 3-3 0.551
msl-1 male-specific lethal 1 0.551
Gap1 GTPase-activating protein 1 0.536
Nipped-A CG33554 gene product from transcript CG33554-RE 0.502
e(y)3 enhancer of yellow 3 0.420
lwr lesswright 0.407
CG10107 CG10107 gene product from transcript CG10107-RA 0.394
egg eggless 0.384
NC2beta CG4185 gene product from transcript CG4185-RA 0.376
SuUR Suppressor of Under-Replication 0.350
Rga Regena 0.333
noi noisette 0.312
Rpd3 CG7471 gene product from transcript CG7471-RA 0.306
mod(mdg4) modifier of mdg4 0.299
bon bonus 0.299
Kr Kruppel 0.291
Tao-1 CG14217 gene product from transcript CG14217-RF 0.287
O-fut1 O-fucosyltransferase 1 0.283
dom domino 0.275
Rpb4 CG33520 gene product from transcript CG33520-RF 0.267
dalao CG7055 gene product from transcript CG7055-RA 0.260
slp1 sloppy paired 1 0.251
Eip75B Ecdysone-induced protein 75B 0.225
Nf-YB Nuclear factor Y-box B 0.213
sno strawberry notch 0.210
wapl wings apart-like 0.209
Scm Sex comb on midleg 0.203
Chro Chromator 0.178
cyc cycle 0.178
Gmd GDP-mannose 4,6-dehydratase 0.175
ksr kinase suppressor of ras 0.164
Abl Abl tyrosine kinase 0.152
CG3995 CG3995 gene product from transcript CG3995-RA 0.143
ush u-shaped 0.141
CG11242 CG11242 gene product from transcript CG11242-RA 0.140
SRm160 CG11274 gene product from transcript CG11274-RA 0.139
l(2)37Cb lethal (2) 37Cb 0.136
glo glorund 0.136
Hand CG18144 gene product from transcript CG18144-RA 0.135
Deaf1 Deformed epidermal autoregulatory factor-1 0.130
Mfap1 Microfibril-associated protein 1 0.129
cwo clockwork orange 0.129
Ino80 CG31212 gene product from transcript CG31212-RA 0.122
Su(var)3-7 Suppressor of variegation 3-7 0.121
CtBP C-terminal Binding Protein 0.115
Cdc27 CG8610 gene product from transcript CG8610-RA 0.114
egr eiger 0.113
SelD Selenide,water dikinase 0.112
CSN5 COP9 complex homolog subunit 5 0.112
CG42672 CG42672 gene product from transcript CG42672-RD 0.112
Ada2b CG9638 gene product from transcript CG9638-RA 0.110
px plexus 0.110
krz kurtz 0.108
dbe dribble 0.107
aly always early 0.107
byn brachyenteron 0.107
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.107
Aut1 CG6877 gene product from transcript CG6877-RA 0.106
Bap55 Brahma associated protein 55kD 0.103
CG9018 CG9018 gene product from transcript CG9018-RA 0.100
CG8443 CG8443 gene product from transcript CG8443-RA 0.099
brat brain tumor 0.098
pr-set7 CG3307 gene product from transcript CG3307-RC 0.096
simj simjang 0.095
Spt5 CG7626 gene product from transcript CG7626-RA 0.095
Su(z)2 Suppressor of zeste 2 0.094
pzg putzig 0.093
CG32343 CG32343 gene product from transcript CG32343-RB 0.092
Taf6 TBP-associated factor 6 0.092
l(3)mbt lethal (3) malignant brain tumor 0.090
SMC1 CG6057 gene product from transcript CG6057-RA 0.090
Su(H) Suppressor of Hairless 0.087
CG16812 CG16812 gene product from transcript CG16812-RA 0.084
HLH54F CG5005 gene product from transcript CG5005-RA 0.084
Pc Polycomb 0.083
Kap-alpha3 karyopherin alpha3 0.083
Mad Mothers against dpp 0.077
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
WDR5 WD repeat domain 5 1.000
TP53 tumor protein p53 1.000
CREBBP CREB binding protein 1.000
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 1.000
TRRAP transformation/transcription domain-associated protein 0.999
KAT2A K(lysine) acetyltransferase 2A 0.996
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.996
KAT2B K(lysine) acetyltransferase 2B 0.995
C20orf20 chromosome 20 open reading frame 20 0.992
JUN jun proto-oncogene 0.989
TBP TATA box binding protein 0.976
HDAC1 histone deacetylase 1 0.973
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.972
DUSP1 dual specificity phosphatase 1 0.969
ACTL6A actin-like 6A 0.966
SIRT1 sirtuin 1 0.955
RUVBL2 RuvB-like 2 (E. coli) 0.953
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.947
USP22 ubiquitin specific peptidase 22 0.930
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.919
MORF4L1 mortality factor 4 like 1 0.901
MYST1 MYST histone acetyltransferase 1 0.897
HDAC2 histone deacetylase 2 0.891
CBX5 chromobox homolog 5 0.885
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.879
TRIM28 tripartite motif containing 28 0.866
RBBP5 retinoblastoma binding protein 5 0.865
HCFC1 host cell factor C1 (VP16-accessory protein) 0.859
NCOA6 nuclear receptor coactivator 6 0.845
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.843
YY1 YY1 transcription factor 0.828
HIST1H3B histone cluster 1, H3b 0.819
TAL1 T-cell acute lymphocytic leukemia 1 0.818
NCOA1 nuclear receptor coactivator 1 0.808
RBBP4 retinoblastoma binding protein 4 0.806
EP300 E1A binding protein p300 0.797
NCOA2 nuclear receptor coactivator 2 0.791
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3 0.791
DAXX death-domain associated protein 0.785
HIST2H3C histone cluster 2, H3c 0.772
KAT5 K(lysine) acetyltransferase 5 0.765
RBBP7 retinoblastoma binding protein 7 0.762
RB1 retinoblastoma 1 0.736
MEN1 multiple endocrine neoplasia I 0.727
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.699
AR androgen receptor 0.684
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.684
MBIP MAP3K12 binding inhibitory protein 1 0.647
LNX1 ligand of numb-protein X 1 0.613
ING3 inhibitor of growth family, member 3 0.606
MRFAP1 Morf4 family associated protein 1 0.595
CFL1 cofilin 1 (non-muscle) 0.591
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.584
ELP2 elongation protein 2 homolog (S. cerevisiae) 0.581
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.580
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.566
DOT1L DOT1-like, histone H3 methyltransferase (S. cerevisiae) 0.564
CXXC1 CXXC finger protein 1 0.559
SMAD7 SMAD family member 7 0.542
MAGEA3 melanoma antigen family A, 3 0.535
BCL9 B-cell CLL/lymphoma 9 0.531
CHD8 chromodomain helicase DNA binding protein 8 0.501
PAX3 paired box 3 0.489
CCNT1 cyclin T1 0.487
STAG2 stromal antigen 2 0.483
NCOA3 nuclear receptor coactivator 3 0.479
TADA3 transcriptional adaptor 3 0.474
POLE3 polymerase (DNA directed), epsilon 3 (p17 subunit) 0.470
UBE3A ubiquitin protein ligase E3A 0.467
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.453
ELP4 elongation protein 4 homolog (S. cerevisiae) 0.448
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.436
SETD7 SET domain containing (lysine methyltransferase) 7 0.435
POU3F2 POU class 3 homeobox 2 0.429
LMO4 LIM domain only 4 0.427
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.426
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.425
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.421
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 0.417
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.417
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.408
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.406
PPP1R15A protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.403
ELP3 elongation protein 3 homolog (S. cerevisiae) 0.391
GSK3B glycogen synthase kinase 3 beta 0.390
BRCA1 breast cancer 1, early onset 0.389
ATXN7 ataxin 7 0.384
MAGEA12 melanoma antigen family A, 12 0.371
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.371
POU5F1 POU class 5 homeobox 1 0.370
RUNX1 runt-related transcription factor 1 0.361
SKI v-ski sarcoma viral oncogene homolog (avian) 0.353
CTAG1B cancer/testis antigen 1B 0.352
NAP1L5 nucleosome assembly protein 1-like 5 0.346
MAGEA6 melanoma antigen family A, 6 0.345
MAPK14 mitogen-activated protein kinase 14 0.342
APP amyloid beta (A4) precursor protein 0.339
ZNF496 zinc finger protein 496 0.334
ZNF148 zinc finger protein 148 0.331
VAC14 Vac14 homolog (S. cerevisiae) 0.329
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Tmsb4x thymosin beta 4, X-linked 0.024
Cfl1 cofilin 1, non-muscle 0.022
Tuba1c tubulin, alpha 1C 0.020
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.015
Casp2 caspase 2 0.013
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.012
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.011
Ubb ubiquitin B 0.011