The network for 'regulation of catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
KSP1 Ksp1p 0.504
PPH21 Pph21p 0.455
BCK1 Bck1p 0.443
CDC55 Cdc55p 0.381
RHO1 Rho1p 0.303
GLC7 Glc7p 0.302
CDC20 Cdc20p 0.285
HSV2 Hsv2p 0.246
ATG20 Atg20p 0.238
MIG1 Mig1p 0.237
CBF2 Cbf2p 0.229
FAR1 Far1p 0.223
STE11 Ste11p 0.213
CRZ1 Crz1p 0.213
HSP42 Hsp42p 0.208
PPZ1 Ppz1p 0.203
CLB3 Clb3p 0.200
STI1 Sti1p 0.196
CDC23 Cdc23p 0.193
MBF1 Mbf1p 0.192
CDC16 Cdc16p 0.191
BCY1 Bcy1p 0.190
YPT7 Ypt7p 0.186
BEM3 Bem3p 0.173
STE20 Ste20p 0.172
STE5 Ste5p 0.166
TOF2 Tof2p 0.164
PKH2 Pkh2p 0.159
GDS1 Gds1p 0.158
TOR1 Tor1p 0.157
CDC24 Cdc24p 0.154
KOG1 Kog1p 0.154
SGV1 Sgv1p 0.153
CAK1 Cak1p 0.153
DAM1 Dam1p 0.152
TRS65 Trs65p 0.152
SUI3 Sui3p 0.152
SNF4 Snf4p 0.149
SLT2 Slt2p 0.149
GLN3 Gln3p 0.144
ORC1 Orc1p 0.140
UBR1 Ubr1p 0.140
RGA2 Rga2p 0.138
CTF13 Ctf13p 0.137
IME2 Ime2p 0.136
HHT1 Hht1p 0.133
SHP1 Shp1p 0.133
APP1 App1p 0.132
FLO8 Flo8p 0.130
RAS2 Ras2p 0.128
SIP2 Sip2p 0.128
PKP2 Pkp2p 0.127
STE4 Ste4p 0.127
SEC4 Sec4p 0.127
RPO21 Rpo21p 0.126
ADR1 Adr1p 0.126
REG1 Reg1p 0.124
MMR1 Mmr1p 0.123
ERV25 Erv25p 0.123
NUP170 Nup170p 0.122
ROM2 Rom2p 0.122
BOI2 Boi2p 0.122
MAD2 Mad2p 0.122
SET2 Set2p 0.121
RPT6 Rpt6p 0.118
MND2 Mnd2p 0.117
YAK1 Yak1p 0.117
IML3 Iml3p 0.116
DCP2 Dcp2p 0.115
GSY2 Gsy2p 0.115
NEM1 Nem1p 0.115
EAF1 Eaf1p 0.115
NET1 Net1p 0.114
BMH2 Bmh2p 0.113
SGT2 Sgt2p 0.112
MLC1 Mlc1p 0.111
CLN3 Cln3p 0.111
TPK1 Tpk1p 0.111
SMC4 Smc4p 0.110
HSE1 Hse1p 0.109
CRN1 Crn1p 0.109
MKK1 Mkk1p 0.109
SWE1 Swe1p 0.108
MCM21 Mcm21p 0.106
TPK2 Tpk2p 0.106
ATG3 Atg3p 0.106
NBL1 Nbl1p 0.106
OKP1 Okp1p 0.104
CDC27 Cdc27p 0.104
YCR007C hypothetical protein 0.104
SLI15 Sli15p 0.102
NTO1 Nto1p 0.102
HHO1 Hho1p 0.102
YPT31 Ypt31p 0.101
SCH9 Sch9p 0.100
SEC16 Sec16p 0.100
ABP1 Abp1p 0.099
PIG2 Pig2p 0.098
YPT53 Ypt53p 0.098
MSN5 Msn5p 0.097
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.598
hgrs-1 Protein HGRS-1 0.369
rme-4 Protein RME-4 0.349
egl-18 Protein EGL-18 0.312
bet-2 Protein BET-2 0.236
stam-1 Protein STAM-1 0.217
unc-45 Protein UNC-45 0.212
air-1 Protein AIR-1 0.199
mrck-1 Protein MRCK-1 0.197
CELE_F47G4.4 Protein F47G4.4 0.194
daf-3 Protein DAF-3 0.192
daf-1 Protein DAF-1 0.191
sma-6 Protein SMA-6 0.183
scd-1 Protein SCD-1 0.180
daf-4 Protein DAF-4 0.179
skn-1 Protein SKN-1 0.179
tam-1 Protein TAM-1 0.178
gpr-1 Protein GPR-1 0.174
unc-62 Protein UNC-62 0.174
rab-5 Protein RAB-5 0.172
rpn-7 Protein RPN-7 0.172
lag-1 Protein LAG-1 0.169
cks-1 Protein CKS-1 0.166
imb-2 Protein IMB-2 0.163
atx-3 Protein ATX-3 0.162
lsy-2 Protein LSY-2 0.157
sel-2 Protein SEL-2 0.155
goa-1 Protein GOA-1 0.155
hmr-1 Protein HMR-1 0.153
CELE_F25B4.5 Protein F25B4.5 0.151
egl-13 Protein EGL-13 0.148
mcm-7 Protein MCM-7 0.146
trcs-2 Protein TRCS-2 0.145
zoo-1 Protein ZOO-1 0.133
miro-1 Protein MIRO-1 0.133
mel-11 Protein MEL-11 0.133
jnk-1 Protein JNK-1 0.133
cki-2 Protein CKI-2 0.133
rpn-6.1 Protein RPN-6.1 0.128
cul-1 Protein CUL-1 0.128
par-5 Protein PAR-5 0.122
ifg-1 Protein IFG-1 0.121
C11E4.6 Protein C11E4.6 0.119
sur-2 Protein SUR-2 0.119
ztf-7 Protein ZTF-7 0.119
glit-1 Protein GLIT-1 0.119
CELE_Y69A2AR.16 Protein Y69A2AR.16 0.117
tpxl-1 Protein TPXL-1 0.117
M88.7 Protein M88.7 0.114
pabp-2 Protein PABP-2 0.114
tag-343 Protein TAG-343 0.112
stau-1 Protein STAU-1 0.112
smp-1 Protein SMP-1 0.111
T23F11.1 Protein T23F11.1 0.109
sea-2 Protein SEA-2 0.108
ect-2 Protein ECT-2 0.105
egl-8 Protein EGL-8 0.105
unc-52 Protein UNC-52 0.104
obr-3 Protein OBR-3 0.102
R11A8.7 Protein R11A8.7 0.102
vps-28 Protein VPS-28 0.102
cand-1 Protein CAND-1 0.101
rhgf-2 Protein RHGF-2 0.100
smk-1 Protein SMK-1 0.100
abts-1 Protein ABTS-1 0.100
ykt-6 Protein YKT-6 0.098
pat-12 Protein PAT-12 0.096
csn-3 Protein CSN-3 0.095
unc-70 Protein UNC-70 0.095
dpy-31 Protein DPY-31 0.095
itr-1 Protein ITR-1 0.094
sli-1 Protein SLI-1 0.094
mom-5 Protein MOM-5 0.094
mtm-3 Protein MTM-3 0.094
eor-1 Protein EOR-1 0.094
CELE_B0285.4 Protein B0285.4 0.093
mpk-1 Protein MPK-1 0.090
sax-3 Protein SAX-3 0.088
mex-5 Protein MEX-5 0.087
unc-16 Protein UNC-16 0.086
lin-45 Protein LIN-45 0.086
ape-1 Protein APE-1 0.085
atg-7 Protein ATG-7 0.085
trr-1 Protein TRR-1 0.083
let-60 Protein LET-60 0.082
unc-14 Protein UNC-14 0.081
sop-3 Protein SOP-3 0.081
pde-4 Protein PDE-4 0.080
ajm-1 Protein AJM-1 0.080
sup-17 Protein SUP-17 0.079
atg-11 Protein ATG-11 0.079
arf-3 Protein ARF-3 0.076
bar-1 Protein BAR-1 0.076
F31C3.2 Protein F31C3.2 0.076
CELE_Y57G11C.3 Protein Y57G11C.3 0.076
madf-5 Protein MADF-5 0.075
atg-2 Protein ATG-2 0.075
gap-2 Protein GAP-2 0.075
ttx-1 Protein TTX-1 0.073
daf-14 Protein DAF-14 0.073
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Danio rerio
Name Description Probability Func Analog Organism
sox9a SRY-box containing gene 9a 0.015
tnni2a.4 troponin I, skeletal, fast 2a.4 0.014
sox32 SRY-box containing gene 32 0.014
tbx1 T-box 1 0.013
pcna proliferating cell nuclear antigen 0.012
chd chordin 0.012
vangl2 vang-like 2 (van gogh, Drosophila) 0.011
ccnb1 cyclin B1 0.011
acvr1b activin A receptor, type IB 0.011
bmp2b bone morphogenetic protein 2b 0.011
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.011
sox9b SRY-box containing gene 9b 0.010
s1pr2 sphingosine-1-phosphate receptor 2 0.010
itgb1b integrin, beta 1b 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.998
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.996
Akt1 CG4006 gene product from transcript CG4006-RA 0.931
Stat92E Signal-transducer and activator of transcription protein at 92E 0.921
InR Insulin-like receptor 0.893
Mad Mothers against dpp 0.881
N Notch 0.869
Pten CG5671 gene product from transcript CG5671-RB 0.832
Atg18 Autophagy-specific gene 18 0.822
G-ialpha65A G protein alphai subunit 65A 0.788
ttk tramtrack 0.780
Rho1 CG8416 gene product from transcript CG8416-RB 0.763
rl rolled 0.757
SNF1A SNF1A/AMP-activated protein kinase 0.727
Dcr-2 Dicer-2 0.723
stg string 0.713
Hnf4 Hepatocyte nuclear factor 4 0.710
Rheb CG1081 gene product from transcript CG1081-RA 0.701
gig gigas 0.687
CG11347 CG11347 gene product from transcript CG11347-RE 0.670
Atg2 Autophagy-specific gene 2 0.669
mts microtubule star 0.655
Plc21C Phospholipase C at 21C 0.650
RanGap Ran GTPase activating protein 0.646
sax saxophone 0.627
Pkn Protein kinase related to protein kinase N 0.625
Rpd3 CG7471 gene product from transcript CG7471-RA 0.624
smo smoothened 0.619
Atg1 Autophagy-specific gene 1 0.616
TER94 CG2331 gene product from transcript CG2331-RA 0.606
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.604
Smox Smad on X 0.603
Khc Kinesin heavy chain 0.574
puc puckered 0.574
Atg8a Autophagy-specific gene 8a 0.565
tkv thickveins 0.559
neur neuralized 0.558
tefu telomere fusion 0.556
CycA Cyclin A 0.536
mys myospheroid 0.520
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.501
msps mini spindles 0.499
SF2 CG6987 gene product from transcript CG6987-RA 0.497
nej nejire 0.493
spin spinster 0.492
drk downstream of receptor kinase 0.490
tws twins 0.472
unc-104 CG8566 gene product from transcript CG8566-RB 0.468
Rbp6 RNA-binding protein 6 0.461
msn misshapen 0.456
trpml transient receptor potential mucolipin 0.454
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.453
CSN4 COP9 complex homolog subunit 4 0.452
Fmr1 CG6203 gene product from transcript CG6203-RC 0.450
Sod Superoxide dismutase 0.449
EcR Ecdysone receptor 0.447
Mnt CG13316 gene product from transcript CG13316-RD 0.432
Stam Signal transducing adaptor molecule 0.430
nwk nervous wreck 0.427
cenG1A centaurin gamma 1A 0.427
dco discs overgrown 0.425
p53 CG33336 gene product from transcript CG33336-RB 0.423
prod proliferation disrupter 0.417
BEAF-32 Boundary element-associated factor of 32kD 0.410
bif bifocal 0.406
drpr draper 0.406
bsk basket 0.375
Sir2 CG5216 gene product from transcript CG5216-RA 0.375
Mmp1 Matrix metalloproteinase 1 0.370
Tsc1 CG6147 gene product from transcript CG6147-RA 0.369
jar jaguar 0.369
CG2924 CG2924 gene product from transcript CG2924-RA 0.368
Sbf SET domain binding factor 0.361
car carnation 0.359
RagA CG11968 gene product from transcript CG11968-RA 0.357
p38b CG7393 gene product from transcript CG7393-RA 0.354
stumps CG31317 gene product from transcript CG31317-RC 0.351
Cul-4 Cullin-4 0.351
plexB plexin B 0.342
Dhc64C Dynein heavy chain 64C 0.330
dys dysfusion 0.324
Vha55 Vacuolar H[+]-ATPase 55kD B subunit 0.322
baz bazooka 0.321
koi klaroid 0.319
Zyx102EF CG32018 gene product from transcript CG32018-RA 0.317
Su(H) Suppressor of Hairless 0.316
CG3680 CG3680 gene product from transcript CG3680-RA 0.316
Dab Disabled 0.314
Su(dx) Suppressor of deltex 0.312
Ard1 Arrest defective 1 0.309
th thread 0.308
trio CG18214 gene product from transcript CG18214-RA 0.308
rap retina aberrant in pattern 0.305
dlt discs lost 0.300
dnc dunce 0.292
chico CG5686 gene product from transcript CG5686-RB 0.289
egr eiger 0.288
egg eggless 0.283
Tl Toll 0.282
LanA Laminin A 0.281
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.294
Homer1 homer homolog 1 (Drosophila) 0.249
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.205
Hk1 hexokinase 1 0.204
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.178
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.172
Caprin1 cell cycle associated protein 1 0.168
Acadvl acyl-Coenzyme A dehydrogenase, very long chain 0.160
Myl9 myosin, light chain 9, regulatory 0.156
Cyth1 cytohesin 1 0.154
Anxa2 annexin A2 0.148
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.144
Epas1 endothelial PAS domain protein 1 0.142
Tagln transgelin 0.140
Acta2 smooth muscle alpha-actin 0.138
Eef2 eukaryotic translation elongation factor 2 0.138
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.137
Mapk9 mitogen-activated protein kinase 9 0.135
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.134
Pja2 praja 2, RING-H2 motif containing 0.134
Vsnl1 visinin-like 1 0.133
Gja1 gap junction protein, alpha 1 0.128
Ubn2 ubinuclein 2 0.127
Mgat5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.124
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.120
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.118
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.117
Eci2 enoyl-Coenzyme A delta isomerase 2 0.117
Arpc2 actin related protein 2/3 complex, subunit 2 0.115
Akap1 A kinase (PRKA) anchor protein 1 0.112
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.107
Gip gastric inhibitory polypeptide 0.107
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.105
Ccr5 chemokine (C-C motif) receptor 5 0.103
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.102
Lphn2 latrophilin 2 0.102
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.102
Hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit 0.101
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.100
Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.100
Myo1b myosin Ib 0.100
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.098
Nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 0.098
Mprip myosin phosphatase Rho interacting protein 0.098
Shank3 SH3 and multiple ankyrin repeat domains 3 0.096
Csnk1g2 casein kinase 1, gamma 2 0.094
Snap25 synaptosomal-associated protein 25 0.092
Ear11 eosinophil-associated, ribonuclease A family, member 11 0.092
Usf2 upstream transcription factor 2, c-fos interacting 0.092
Nras neuroblastoma ras oncogene 0.091
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.091
Klrb1a killer cell lectin-like receptor subfamily B, member 1A 0.090
Junb jun B proto-oncogene 0.089
Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.089
Prdm2 PR domain containing 2, with ZNF domain 0.089
RGD1305793 similar to hypothetical protein FLJ20154 0.087
Rap1b RAP1B, member of RAS oncogene family 0.087
Racgap1 Rac GTPase-activating protein 1 0.087
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.086
Hist1h1a histone cluster 1, H1a 0.085
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.083
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.083
Hand2 heart and neural crest derivatives expressed 2 0.083
Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 0.083
Pla2g2c phospholipase A2, group IIC 0.082
Ncan neurocan 0.082
Slc25a42 solute carrier family 25, member 42 0.081
Zfp260 zinc finger protein 260 0.079
Mapre3 microtubule-associated protein, RP/EB family, member 3 0.077
Casp2 caspase 2 0.077
Abi1 abl-interactor 1 0.077
Sox17 SRY (sex determining region Y)-box 17 0.076
Dlg3 discs, large homolog 3 (Drosophila) 0.076
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.076
Rgs19 regulator of G-protein signaling 19 0.076
Cyb5r4 cytochrome b5 reductase 4 0.075
Dgka diacylglycerol kinase, alpha 0.075
Tpm3 tropomyosin 3, gamma 0.075
Nckap1 NCK-associated protein 1 0.074
Picalm phosphatidylinositol binding clathrin assembly protein 0.074
Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 0.073
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.073
Cdk7 cyclin-dependent kinase 7 0.073
Prrx1 paired related homeobox 1 0.073
Gipc1 GIPC PDZ domain containing family, member 1 0.073
Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.072
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.072
Litaf lipopolysaccharide-induced TNF factor 0.072
Atf3 activating transcription factor 3 0.072
Copb1 coatomer protein complex, subunit beta 1 0.072
Ryr2 ryanodine receptor 2, cardiac 0.072
Snap29 synaptosomal-associated protein 29 0.072
Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.071
Irs1 insulin receptor substrate 1 0.071
Crip2 cysteine-rich protein 2 0.071
Cd36 CD36 molecule (thrombospondin receptor) 0.071
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.070
Top2a topoisomerase (DNA) II alpha 0.070
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.070
Ccnb1 cyclin B1 0.070