The network for 'positive regulation of biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CHD1 Chd1p 0.981
RPD3 Rpd3p 0.977
HOG1 Hog1p 0.976
YAP1 Yap1p 0.971
LSM1 Lsm1p 0.969
GLN3 Gln3p 0.968
SIN3 Sin3p 0.968
RTF1 Rtf1p 0.944
SWI6 Swi6p 0.938
FKH2 Fkh2p 0.917
ADA2 Ada2p 0.914
MKS1 Mks1p 0.913
URE2 Ure2p 0.908
GAL11 Gal11p 0.905
YTA7 Yta7p 0.903
MET4 Met4p 0.900
SNF6 Snf6p 0.888
RGR1 Rgr1p 0.878
PGD1 Pgd1p 0.875
SPT15 Spt15p 0.863
SNF2 Snf2p 0.844
RXT2 Rxt2p 0.837
SPT16 Spt16p 0.831
SNF5 Snf5p 0.824
HSP78 Hsp78p 0.823
RVB2 Rvb2p 0.822
MSN2 Msn2p 0.809
SPT8 Spt8p 0.803
AFT1 Aft1p 0.801
CDC28 Cdc28p 0.800
RTG3 Rtg3p 0.798
GCN5 Gcn5p 0.795
HHF1 Hhf1p 0.789
SWI1 Swi1p 0.788
CTR9 Ctr9p 0.786
NRG1 Nrg1p 0.770
YAK1 Yak1p 0.769
SRB4 Srb4p 0.765
RPT6 Rpt6p 0.760
SRB5 Srb5p 0.753
MED2 Med2p 0.726
SGV1 Sgv1p 0.718
SAP185 Sap185p 0.715
CTK3 Ctk3p 0.703
RIM101 Rim101p 0.687
CDC39 Cdc39p 0.681
ARP9 Arp9p 0.680
SET3 Set3p 0.669
TAF14 Taf14p 0.662
HTA2 Hta2p 0.661
CGI121 Cgi121p 0.655
ROX3 Rox3p 0.655
SET2 Set2p 0.641
MSN1 Msn1p 0.635
DOT6 Dot6p 0.620
STE12 Ste12p 0.617
UTP22 Utp22p 0.610
MTR10 Mtr10p 0.605
MSN4 Msn4p 0.604
DST1 Dst1p 0.603
RSC58 Rsc58p 0.598
NAM7 Nam7p 0.590
CSE2 Cse2p 0.585
CTI6 Cti6p 0.581
MED6 Med6p 0.579
HAP5 Hap5p 0.579
STP2 Stp2p 0.574
MED8 Med8p 0.565
TAF10 Taf10p 0.557
YKE2 Yke2p 0.542
MED1 Med1p 0.541
NUT2 Nut2p 0.534
SWI3 Swi3p 0.534
CDC55 Cdc55p 0.533
DIG1 Dig1p 0.532
DOM34 Dom34p 0.528
RSP5 Rsp5p 0.520
UTP9 Utp9p 0.517
UBP6 Ubp6p 0.512
SRB2 Srb2p 0.508
CKA2 Cka2p 0.506
MCM1 Mcm1p 0.503
EAF5 Eaf5p 0.503
BMH1 Bmh1p 0.501
SAP30 Sap30p 0.501
HDA2 Hda2p 0.496
AHC1 Ahc1p 0.496
UTP7 Utp7p 0.495
HST1 Hst1p 0.491
HMO1 Hmo1p 0.486
NUP157 Nup157p 0.486
VPS27 Vps27p 0.484
NUP100 Nup100p 0.483
ATG1 Atg1p 0.482
SDS3 Sds3p 0.481
FIG4 Fig4p 0.480
SPT7 Spt7p 0.478
RSC4 Rsc4p 0.477
CYC8 Cyc8p 0.477
GIS1 Gis1p 0.476
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
pha-4 Protein PHA-4 0.996
vab-3 Protein VAB-3 0.969
egl-18 Protein EGL-18 0.959
set-1 Protein SET-1 0.872
fkh-2 Protein FKH-2 0.864
nhr-49 Protein NHR-49 0.823
eya-1 Protein EYA-1 0.784
egl-13 Protein EGL-13 0.778
elt-6 Protein ELT-6 0.747
hbl-1 Protein HBL-1 0.725
ced-9 Protein CED-9 0.655
T28F4.1 Protein T28F4.1 0.630
npp-2 Protein NPP-2 0.614
pry-1 Protein PRY-1 0.613
bar-1 Protein BAR-1 0.588
mab-5 Protein MAB-5 0.571
unc-62 Protein UNC-62 0.535
nhr-67 Protein NHR-67 0.527
zfp-1 Protein ZFP-1 0.503
unc-42 Protein UNC-42 0.480
vab-1 Protein VAB-1 0.470
sax-3 Protein SAX-3 0.461
nhr-34 Protein NHR-34 0.458
tbx-9 Protein TBX-9 0.454
egl-46 Protein EGL-46 0.453
mat-3 Protein MAT-3 0.450
rps-2 Protein RPS-2 0.436
daf-3 Protein DAF-3 0.435
his-1 Protein HIS-1 0.426
nhr-6 Protein NHR-6 0.424
CELE_C17E4.6 Protein C17E4.6 0.423
hlh-2 Protein HLH-2 0.418
daf-1 Protein DAF-1 0.417
ceh-34 Protein CEH-34 0.405
lin-17 Protein LIN-17 0.403
cfim-2 Protein CFIM-2 0.397
cam-1 Protein CAM-1 0.392
pch-2 Protein PCH-2 0.379
lin-36 Protein LIN-36 0.375
K10D6.4 Protein K10D6.4 0.375
T23F4.2 Protein T23F4.2 0.370
ten-1 Protein TEN-1 0.364
let-60 Protein LET-60 0.362
soc-2 Protein SOC-2 0.359
mdf-2 Protein MDF-2 0.358
daf-14 Protein DAF-14 0.348
bet-1 Protein BET-1 0.339
hmg-1.2 Protein HMG-1.2 0.334
F12F6.1 Protein F12F6.1 0.322
asb-1 Protein ASB-1 0.319
cki-1 Protein CKI-1 0.315
wrm-1 Protein WRM-1 0.314
rad-26 Protein RAD-26 0.314
nud-2 Protein NUD-2 0.306
saeg-1 Protein SAEG-1 0.296
sel-10 Protein SEL-10 0.295
npp-21 Protein NPP-21 0.293
zyg-1 Protein ZYG-1 0.289
nhr-25 Protein NHR-25 0.289
zip-7 Protein ZIP-7 0.289
sdz-28 Protein SDZ-28 0.287
unc-73 Protein UNC-73 0.286
B0205.9 Protein B0205.9 0.272
age-1 Protein AGE-1 0.267
CELE_F19F10.9 Protein F19F10.9 0.267
attf-2 Protein ATTF-2 0.265
T28D9.4 Protein T28D9.4 0.257
ntl-4 Protein NTL-4 0.254
atgp-1 Protein ATGP-1 0.254
daf-11 Protein DAF-11 0.250
mep-1 Protein MEP-1 0.249
icd-1 Protein ICD-1 0.249
unc-40 Protein UNC-40 0.248
ceh-16 Protein CEH-16 0.246
mls-2 Protein MLS-2 0.244
gei-4 Protein GEI-4 0.242
his-5 Protein HIS-5 0.242
lmn-1 Protein LMN-1 0.240
hlh-14 Protein HLH-14 0.238
F46H5.7 Protein F46H5.7 0.238
egl-44 Protein EGL-44 0.236
R11A8.7 Protein R11A8.7 0.230
tax-4 Protein TAX-4 0.230
C50E3.5 Protein C50E3.5 0.227
flt-1 Protein FLT-1 0.224
sas-4 Protein SAS-4 0.213
abi-1 Protein ABI-1 0.213
rgs-7 Protein RGS-7 0.212
lin-35 Protein LIN-35 0.211
skn-1 Protein SKN-1 0.210
pbrm-1 Protein PBRM-1 0.210
F53E10.6 Protein F53E10.6 0.208
sna-2 Protein SNA-2 0.208
ada-2 Protein ADA-2 0.207
lag-1 Protein LAG-1 0.204
his-31 Protein HIS-31 0.202
F39B2.1 Protein F39B2.1 0.202
unc-43 Protein UNC-43 0.201
skp-1 Protein SKP-1 0.200
klp-18 Protein KLP-18 0.197
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Danio rerio
Name Description Probability Func Analog Organism
notch1a notch homolog 1a 0.967
nkx2.2a NK2 transcription factor related 2a 0.959
gli1 GLI-Kruppel family member 1 0.958
myod1 myogenic differentiation 1 0.923
crabp2a cellular retinoic acid binding protein 2, a 0.920
flh floating head 0.911
chd chordin 0.908
col2a1a collagen type II, alpha-1a 0.875
isl1 islet1 0.870
dlx2a distal-less homeobox gene 2a 0.834
tal1 T-cell acute lymphocytic leukemia 1 0.801
pitx3 paired-like homeodomain transcription factor 3 0.792
lft1 lefty1 0.763
foxi1 forkhead box I1 0.763
tbx20 T-box 20 0.761
tp53 tumor protein p53 0.759
eya1 eyes absent homolog 1 0.756
ascl1a achaete-scute complex-like 1a (Drosophila) 0.747
rx2 retinal homeobox gene 2 0.742
gata3 GATA-binding protein 3 0.733
shha sonic hedgehog a 0.717
bmp4 bone morphogenetic protein 4 0.705
egr1 early growth response 1 0.689
ndr2 nodal-related 2 0.676
jag2 jagged 2 0.667
hnf1ba HNF1 homeobox Ba 0.653
atoh1a atonal homolog 1a 0.640
lhx5 LIM homeobox 5 0.606
her8a hairy-related 8a 0.594
six3b sine oculis homeobox homolog 3b 0.583
runx2b runt-related transcription factor 2b 0.582
fzd8a frizzled homolog 8a 0.580
tp63 tumor protein p63 0.576
gcm2 glial cells missing homolog 2 (Drosophila) 0.525
otpa orthopedia homolog a 0.525
otpb orthopedia homolog b 0.500
fsta follistatin a 0.494
irx7 iroquois homeobox protein 7 0.468
hand2 heart and neural crest derivatives expressed transcript 2 0.464
dlx5a distal-less homeobox gene 5a 0.458
rarab retinoic acid receptor, alpha b 0.448
notch3 notch homolog 3 0.447
prl prolactin 0.443
bmp2b bone morphogenetic protein 2b 0.439
traf4a tnf receptor-associated factor 4a 0.439
pitx2 paired-like homeodomain transcription factor 2 0.426
sox2 SRY-box containing gene 2 0.417
fzd7a frizzled homolog 7a 0.415
fgfr3 fibroblast growth factor receptor 3 0.414
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.411
irx4b iroquois homeobox protein 4b 0.406
fgf3 fibroblast growth factor 3 0.400
hoxb5a homeo box B5a 0.396
ef1a elongation factor 1-alpha 0.392
gata1a GATA binding protein 1a 0.392
foxj1a forkhead box J1a 0.385
fn1 fibronectin 1 0.382
nkx2.5 NK2 transcription factor related 5 0.377
zic4 zic family member 4 0.375
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.369
mef2d myocyte enhancer factor 2d 0.369
sox17 SRY-box containing gene 17 0.367
junb jun B proto-oncogene 0.363
spry4 sprouty (Drosophila) homolog 4 0.361
tbx1 T-box 1 0.357
hhex hematopoietically expressed homeobox 0.356
ptf1a pancreas specific transcription factor, 1a 0.348
hoxc6a homeo box C6a 0.348
sox1a SRY-box containing gene 1a 0.346
lhx1a LIM homeobox 1a 0.345
sox3 SRY-box containing gene 3 0.340
bmp2a bone morphogenetic protein 2a 0.338
evx1 even-skipped homeobox 1 0.333
hoxd11a homeo box D11a 0.331
runx1 runt-related transcription factor 1 0.330
rag1 recombination activating gene 1 0.326
prox1 prospero-related homeobox gene 1 0.324
kdrl kinase insert domain receptor like 0.319
sox9b SRY-box containing gene 9b 0.317
cx43 connexin 43 0.317
nr2f6b nuclear receptor subfamily 2, group F, member 6b 0.314
etv2 ets variant gene 2 0.312
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.311
igf3 insulin-like growth factor 3 0.298
mef2ca myocyte enhancer factor 2ca 0.298
six4b sine oculis homeobox homolog 4b 0.293
tfap2a transcription factor AP-2 alpha 0.291
mespa mesoderm posterior a 0.291
nova2 neuro-oncological ventral antigen 2 0.289
hoxc10a homeo box C10a and homeobox protein Hox-C10a-like 0.287
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.286
pax6a paired box gene 6a 0.285
nrg2a neuregulin 2a 0.283
wnt5b wingless-type MMTV integration site family, member 5b 0.280
has2 hyaluronan synthase 2 0.274
dkk1b dickkopf 1b 0.274
fzd8b frizzled homolog 8b 0.271
oep one-eyed pinhead 0.269
epha4a eph receptor A4a 0.268
cnr1 cannabinoid receptor 1 0.264
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Akt1 CG4006 gene product from transcript CG4006-RA 0.998
wg wingless 0.997
brm brahma 0.996
Ubx Ultrabithorax 0.996
ci cubitus interruptus 0.995
gro groucho 0.993
phl pole hole 0.989
lola longitudinals lacking 0.988
InR Insulin-like receptor 0.988
Fmr1 CG6203 gene product from transcript CG6203-RC 0.977
klu klumpfuss 0.961
Pp2B-14D Protein phosphatase 2B at 14D 0.960
EcR Ecdysone receptor 0.947
kay kayak 0.942
Pc Polycomb 0.934
Mad Mothers against dpp 0.933
dm diminutive 0.929
phyl phyllopod 0.928
ct cut 0.922
bcd bicoid 0.916
bs blistered 0.916
exd extradenticle 0.911
kis kismet 0.910
eyg eyegone 0.910
MED15 Mediator complex subunit 15 0.905
sna snail 0.903
Rel Relish 0.902
Nrg Neuroglian 0.901
BRWD3 CG31132 gene product from transcript CG31132-RA 0.901
mask multiple ankyrin repeats single KH domain 0.898
rho rhomboid 0.897
nmo nemo 0.896
Snr1 Snf5-related 1 0.894
brk brinker 0.892
ush u-shaped 0.891
mrn marionette 0.887
kto kohtalo 0.886
osa CG7467 gene product from transcript CG7467-RD 0.885
Ras85D Ras oncogene at 85D 0.882
Abd-B Abdominal B 0.879
foxo forkhead box, sub-group O 0.877
gcm glial cells missing 0.874
Su(H) Suppressor of Hairless 0.872
Antp Antennapedia 0.867
slmb supernumerary limbs 0.865
fru fruitless 0.859
Pka-C1 cAMP-dependent protein kinase 1 0.859
hth homothorax 0.859
dome domeless 0.857
nub nubbin 0.852
Dredd Death related ced-3/Nedd2-like protein 0.851
CG11347 CG11347 gene product from transcript CG11347-RE 0.847
sd scalloped 0.843
Mpk2 CG5475 gene product from transcript CG5475-RB 0.835
en engrailed 0.832
gsb gooseberry 0.831
key kenny 0.825
E(spl) Enhancer of split 0.823
tin tinman 0.818
jing CG9397 gene product from transcript CG9397-RI 0.818
osk oskar 0.818
sev sevenless 0.816
CG11486 CG11486 gene product from transcript CG11486-RG 0.815
N Notch 0.814
eve even skipped 0.811
CSN8 COP9 complex homolog subunit 8 0.804
mor moira 0.797
Trl Trithorax-like 0.796
Scm Sex comb on midleg 0.794
Dcp-1 Death caspase-1 0.791
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.791
nkd naked cuticle 0.789
hep hemipterous 0.785
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.774
BEAF-32 Boundary element-associated factor of 32kD 0.772
Med Medea 0.770
ap apterous 0.767
Ada2b CG9638 gene product from transcript CG9638-RA 0.765
lz lozenge 0.752
salm spalt major 0.748
pan pangolin 0.747
RYBP Ring and YY1 Binding Protein 0.746
ebi CG4063 gene product from transcript CG4063-RA 0.746
Pcaf CG4107 gene product from transcript CG4107-RA 0.739
slp1 sloppy paired 1 0.733
Bre1 CG10542 gene product from transcript CG10542-RA 0.730
Mef2 Myocyte enhancer factor 2 0.726
drk downstream of receptor kinase 0.721
sens senseless 0.721
ash2 absent, small, or homeotic discs 2 0.718
dac dachshund 0.717
dsh dishevelled 0.712
tral trailer hitch 0.697
pb proboscipedia 0.688
ftz fushi tarazu 0.687
PGRP-LC Peptidoglycan recognition protein LC 0.686
opa odd paired 0.685
Sos Son of sevenless 0.677
p38b CG7393 gene product from transcript CG7393-RA 0.674
prd paired 0.673
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tgfbr2 transforming growth factor, beta receptor II 0.767
S100a10 S100 calcium binding protein A10 0.686
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.664
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.587
Fgfr2 fibroblast growth factor receptor 2 0.573
Junb jun B proto-oncogene 0.571
Met met proto-oncogene 0.555
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.486
Dusp1 dual specificity phosphatase 1 0.485
Rara retinoic acid receptor, alpha 0.457
Fgfr1 Fibroblast growth factor receptor 1 0.425
Map3k3 mitogen activated protein kinase kinase kinase 3 0.422
Shox2 short stature homeobox 2 0.403
Klf6 Kruppel-like factor 6 0.397
Pgc progastricsin (pepsinogen C) 0.394
Agtr1b angiotensin II receptor, type 1b 0.392
Gjb3 gap junction protein, beta 3 0.386
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.379
Phkg1 phosphorylase kinase, gamma 1 0.378
Myh9 myosin, heavy chain 9, non-muscle 0.374
Akt2 v-akt murine thymoma viral oncogene homolog 2 0.361
Egr3 early growth response 3 0.354
Stat6 signal transducer and activator of transcription 6 0.348
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.347
Mprip myosin phosphatase Rho interacting protein 0.347
Zfp36 zinc finger protein 36 0.340
Pnliprp1 pancreatic lipase-related protein 1 0.339
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.336
Jak1 Janus kinase 1 0.336
Bmp6 bone morphogenetic protein 6 0.332
Ppard peroxisome proliferator-activated receptor delta 0.331
Runx1 runt-related transcription factor 1 0.330
Plrg1 pleiotropic regulator 1, PRL1 homolog (Arabidopsis) 0.330
Trhr thyrotropin releasing hormone receptor 0.327
Zyx zyxin 0.316
Tcfe2a transcription factor E2a 0.315
Oxtr oxytocin receptor 0.315
Fos FBJ osteosarcoma oncogene 0.314
Phf12 PHD finger protein 12 0.314
Nfib nuclear factor I/B 0.308
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.307
Map3k1 mitogen activated protein kinase kinase kinase 1 0.307
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.302
Igf2 insulin-like growth factor 2 0.302
Btg2 BTG family, member 2 0.301
Phox2a paired-like homeobox 2a 0.296
Prp15 proline-rich protein 15 0.295
Ptbp1 polypyrimidine tract binding protein 1 0.293
Nr1d1 nuclear receptor subfamily 1, group D, member 1 0.292
Aqp2 aquaporin 2 (collecting duct) 0.292
Col8a1 collagen, type VIII, alpha 1 0.289
Guca2a guanylate cyclase activator 2a (guanylin) 0.289
Jak2 Janus kinase 2 0.287
Proc protein C 0.282
Jun Jun oncogene 0.281
Casp2 caspase 2 0.278
Smad1 SMAD family member 1 0.278
Foxd1 forkhead box D1 0.278
Irs1 insulin receptor substrate 1 0.276
Nkx6-1 NK6 homeobox 1 0.274
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.273
Mapk9 mitogen-activated protein kinase 9 0.271
Umod uromodulin 0.270
Cd40lg CD40 ligand 0.270
Adcy4 adenylate cyclase 4 0.269
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.268
St13 suppression of tumorigenicity 13 0.266
Slc20a2 solute carrier family 20 (phosphate transporter), member 2 0.265
Prkca protein kinase C, alpha 0.264
Tshb thyroid stimulating hormone, beta 0.263
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.260
Ciita class II, major histocompatibility complex, transactivator 0.260
Klf13 Kruppel-like factor 13 0.259
Clcn5 chloride channel 5 0.259
Egr1 early growth response 1 0.258
Prrx1 paired related homeobox 1 0.256
S1pr2 sphingosine-1-phosphate receptor 2 0.256
Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor 0.252
Cnga3 cyclic nucleotide gated channel alpha 3 0.251
Sf1 splicing factor 1 0.251
Usf2 upstream transcription factor 2, c-fos interacting 0.250
Sycn syncollin 0.250
Tcf4 transcription factor 4 0.250
Mrgprf MAS-related GPR, member F 0.250
Gnrhr gonadotropin releasing hormone receptor 0.248
Galr3 galanin receptor 3 0.247
Neurod2 neurogenic differentiation 2 0.247
Myd88 myeloid differentiation primary response gene 88 0.246
Cd86 CD86 molecule 0.246
Ccl3 chemokine (C-C motif) ligand 3 0.245
Kcng2 potassium voltage-gated channel, subfamily G, member 2 0.244
Mef2d myocyte enhancer factor 2D 0.243
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.239
Myadm myeloid-associated differentiation marker 0.239
Ghr growth hormone receptor 0.235
Dcn decorin 0.235
Adam17 ADAM metallopeptidase domain 17 0.234
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.230
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.227
Tgfbr3 transforming growth factor, beta receptor III 0.227