The network for 'meiotic recombination checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

meiotic recombination checkpoint

A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.

Name Description Probability Func Analog Organism
PPH22 Pph22p 0.676
MEK1 Mek1p 0.502
RED1 Red1p 0.461
ZIP1 Zip1p 0.440
PSY4 Psy4p 0.377
HOP1 Hop1p 0.348
PPH21 Pph21p 0.333
ESF1 Esf1p 0.077
CCT2 Cct2p 0.076
PCH2 Pch2p 0.060
RAD5 Rad5p 0.051
PDS1 Pds1p 0.049
REV1 Rev1p 0.043
RRP17 Rrp17p 0.039
REV7 Rev7p 0.038
HOP2 Hop2p 0.037
CKA1 Cka1p 0.036
RAD53 Rad53p 0.034
RAD9 Rad9p 0.033
FPR3 Fpr3p 0.030
HSL1 Hsl1p 0.029
HAL5 Hal5p 0.025
YLR264C-A hypothetical protein 0.024
DIA2 Dia2p 0.024
SWI4 Swi4p 0.024
RLF2 Rlf2p 0.024
PAM1 Pam1p 0.024
CDC55 Cdc55p 0.023
SRD1 Srd1p 0.022
URA3 Ura3p 0.021
YLR162W hypothetical protein 0.021
CMK2 Cmk2p 0.021
LEU2 Leu2p 0.020
RAD17 Rad17p 0.020
ZEO1 Zeo1p 0.020
MRC1 Mrc1p 0.020
SWC7 Swc7p 0.019
MER1 Mer1p 0.019
HXT3 Hxt3p 0.019
YAR068W hypothetical protein 0.017
SET2 Set2p 0.017
YOL038C-A hypothetical protein 0.016
MDN1 Mdn1p 0.016
HO Hop 0.016
DBP10 Dbp10p 0.015
CSM4 Csm4p 0.015
CUP1-1 Cup1-1p 0.015
NPA3 Npa3p 0.015
YKR075C hypothetical protein 0.014
NOP10 Nop10p 0.014
MSG5 Msg5p 0.014
ARP10 Arp10p 0.014
PTR2 Ptr2p 0.014
YNL144C hypothetical protein 0.013
YGR035C hypothetical protein 0.013
ARG8 Arg8p 0.013
ADH2 Adh2p 0.013
ARE2 Are2p 0.013
ZPS1 Zps1p 0.013
RAD55 Rad55p 0.012
ICY1 Icy1p 0.012
YNR014W hypothetical protein 0.012
YLR042C hypothetical protein 0.012
ATP6 Atp6p 0.012
YPR157W hypothetical protein 0.012
YAR066W hypothetical protein 0.012
YJL181W hypothetical protein 0.012
SPL2 Spl2p 0.012
CPD1 Cpd1p 0.012
SIA1 Sia1p 0.012
BRN1 Brn1p 0.012
AUA1 Aua1p 0.012
TPD3 Tpd3p 0.011
HPF1 Hpf1p 0.011
YIR035C hypothetical protein 0.011
TYE7 Tye7p 0.011
OPT2 Opt2p 0.011
YOL013W-A hypothetical protein 0.011
MEI4 Mei4p 0.011
YPL014W hypothetical protein 0.011
SAE2 Sae2p 0.011
NOG1 Nog1p 0.011
YBR013C hypothetical protein 0.011
FMT1 Fmt1p 0.011
TMA22 Tma22p 0.011
MMS1 Mms1p 0.011
NCE103 Nce103p 0.010
BSC1 Bsc1p 0.010
UBP8 Ubp8p 0.010
REC102 Rec102p 0.010
IZH4 Izh4p 0.010
RRP1 Rrp1p 0.010
DMC1 Dmc1p 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.068
N Notch 0.067
Dl Delta 0.056
Egfr Epidermal growth factor receptor 0.033
arm armadillo 0.024
phl pole hole 0.016
wg wingless 0.014
Mad Mothers against dpp 0.012
sgg shaggy 0.011
dpp decapentaplegic 0.011
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Stip1 stress-induced phosphoprotein 1 0.024
Papolg poly(A) polymerase gamma 0.022
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Rattus norvegicus
Name Description Probability Func Analog Organism