The network for 'negative regulation of cell cycle process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cell cycle process

Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GLC7 Glc7p 0.999
RAD53 Rad53p 0.957
KEL1 Kel1p 0.921
CDC28 Cdc28p 0.881
PPH3 Pph3p 0.840
DBF4 Dbf4p 0.759
ZDS2 Zds2p 0.751
BUB3 Bub3p 0.736
SPT16 Spt16p 0.731
SPT5 Spt5p 0.716
SMC4 Smc4p 0.702
RAD9 Rad9p 0.699
CLB3 Clb3p 0.697
ZDS1 Zds1p 0.671
HXT4 Hxt4p 0.632
HSL1 Hsl1p 0.597
CKA2 Cka2p 0.591
KIN1 Kin1p 0.585
PDS1 Pds1p 0.523
CDC20 Cdc20p 0.516
SIC1 Sic1p 0.504
RCO1 Rco1p 0.458
POL30 Pol30p 0.440
HXT6 Hxt6p 0.438
PSY2 Psy2p 0.424
GIC1 Gic1p 0.400
RRM3 Rrm3p 0.377
MCM5 Mcm5p 0.374
TPD3 Tpd3p 0.372
FAR11 Far11p 0.362
PSR2 Psr2p 0.347
DPB2 Dpb2p 0.336
MCM10 Mcm10p 0.335
RAD54 Rad54p 0.334
MTH1 Mth1p 0.331
GBP2 Gbp2p 0.323
HXT7 Hxt7p 0.318
BMH1 Bmh1p 0.316
PPZ2 Ppz2p 0.308
CHL1 Chl1p 0.306
MEK1 Mek1p 0.304
MEC1 Mec1p 0.303
EAF1 Eaf1p 0.301
SLK19 Slk19p 0.293
PPH21 Pph21p 0.287
PPH22 Pph22p 0.284
HOS4 Hos4p 0.280
MCM21 Mcm21p 0.275
ZIP1 Zip1p 0.275
SNT1 Snt1p 0.275
CKA1 Cka1p 0.259
IML3 Iml3p 0.251
MRC1 Mrc1p 0.249
BUB1 Bub1p 0.249
PLC1 Plc1p 0.240
GAC1 Gac1p 0.227
RAD52 Rad52p 0.227
CDC55 Cdc55p 0.226
HST1 Hst1p 0.222
MSA1 Msa1p 0.219
BRN1 Brn1p 0.218
DIA2 Dia2p 0.210
SMC3 Smc3p 0.208
HXT2 Hxt2p 0.203
RED1 Red1p 0.202
CKS1 Cks1p 0.197
CDC7 Cdc7p 0.194
RTS1 Rts1p 0.194
HRR25 Hrr25p 0.192
CDC16 Cdc16p 0.188
STE4 Ste4p 0.187
RAD24 Rad24p 0.186
CDC34 Cdc34p 0.184
UBP8 Ubp8p 0.183
GAL2 Gal2p 0.178
CRN1 Crn1p 0.175
PIG2 Pig2p 0.173
SIF2 Sif2p 0.172
SCC2 Scc2p 0.169
ARC35 Arc35p 0.167
PEX22 Pex22p 0.167
CLB5 Clb5p 0.167
SWI1 Swi1p 0.164
CTF3 Ctf3p 0.159
HOP1 Hop1p 0.154
RAS2 Ras2p 0.153
SDS22 Sds22p 0.151
LTE1 Lte1p 0.151
BIM1 Bim1p 0.144
YMR315W hypothetical protein 0.144
RPO26 Rpo26p 0.142
TPK2 Tpk2p 0.142
ECO1 Eco1p 0.138
SPC110 Spc110p 0.137
SET1 Set1p 0.137
CDC4 Cdc4p 0.136
RIF1 Rif1p 0.135
THO2 Tho2p 0.135
CDC15 Cdc15p 0.134
YNR073C hypothetical protein 0.134
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
lag-1 Protein LAG-1 0.041
csn-5 Protein CSN-5 0.038
plk-1 Protein PLK-1 0.035
top-2 Protein TOP-2 0.033
dsh-2 Protein DSH-2 0.030
hcp-1 Protein HCP-1 0.029
asd-1 Protein ASD-1 0.025
hpo-9 Protein HPO-9 0.025
his-6 Protein HIS-6 0.021
brc-1 Protein BRC-1 0.020
bub-1 Protein BUB-1 0.020
knl-1 Protein KNL-1 0.019
egl-18 Protein EGL-18 0.019
csn-3 Protein CSN-3 0.019
mat-3 Protein MAT-3 0.018
rnr-1 Protein RNR-1 0.018
hsr-9 Protein HSR-9 0.018
lin-9 Protein LIN-9 0.017
dpl-1 Protein DPL-1 0.016
hcf-1 Protein HCF-1 0.015
cep-1 Protein CEP-1 0.015
T26A5.5 Protein T26A5.5 0.015
npp-21 Protein NPP-21 0.014
air-1 Protein AIR-1 0.014
smc-3 Protein SMC-3 0.014
T22C1.1 Protein T22C1.1 0.014
atg-18 Protein ATG-18 0.014
C01G5.6 Protein C01G5.6 0.014
panl-2 Protein PANL-2 0.014
spd-5 Protein SPD-5 0.014
chk-1 Protein CHK-1 0.014
set-1 Protein SET-1 0.013
CELE_C24H12.5 Protein C24H12.5 0.013
crt-1 Protein CRT-1 0.013
ran-1 Protein RAN-1 0.013
D1081.8 Protein D1081.8 0.013
his-32 Protein HIS-32 0.013
air-2 Protein AIR-2 0.013
T19H12.2 Protein T19H12.2 0.013
CELE_F52C6.12 Protein F52C6.12 0.013
rla-0 Protein RLA-0 0.012
swsn-7 Protein SWSN-7 0.012
isw-1 Protein ISW-1 0.012
lig-1 Protein LIG-1 0.012
pcn-1 Protein PCN-1 0.012
xpo-1 Protein XPO-1 0.012
cul-1 Protein CUL-1 0.012
CELE_W02A11.1 Protein W02A11.1 0.011
lin-8 Protein LIN-8 0.011
hrp-1 Protein HRP-1 0.011
mex-5 Protein MEX-5 0.011
cnd-1 Protein CND-1 0.011
daf-2 Protein DAF-2 0.011
pri-2 Protein PRI-2 0.011
fnta-1 Protein FNTA-1 0.011
lex-1 Protein LEX-1 0.010
lsy-22 Protein LSY-22 0.010
npp-16 Protein NPP-16 0.010
mcm-5 Protein MCM-5 0.010
cdc-6 Protein CDC-6 0.010
rps-15 Protein RPS-15 0.010
fox-1 Protein FOX-1 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ccnb1 cyclin B1 0.568
map2k4a mitogen-activated protein kinase kinase 4a 0.371
smad9 MAD homolog 9 (Drosophila) 0.363
smc4 structural maintenance of chromosomes 4 0.348
wnt4a wingless-type MMTV integration site family, member 4a 0.310
nrg1 neuregulin 1 0.295
kif23 kinesin family member 23 0.267
ccnb2 cyclin B2 0.261
dtl denticleless homolog (Drosophila) 0.231
ccna2 cyclin A2 0.214
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.212
skp2 S-phase kinase-associated protein 2 (p45) 0.203
ccnd1 cyclin D1 0.196
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.180
plk1 polo-like kinase 1 (Drosophila) 0.163
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.163
oep one-eyed pinhead 0.152
csnk1da casein kinase 1, delta a 0.146
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.144
nusap1 nucleolar and spindle associated protein 1 0.142
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.140
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.134
wnt11r wingless-type MMTV integration site family, member 11, related 0.133
orc6 origin recognition complex, subunit 6 0.128
mos v-mos Moloney murine sarcoma viral oncogene homolog 0.102
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.097
zgc:174506 zgc:174506 0.084
e2f5 E2F transcription factor 5 0.081
bon bonnie and clyde 0.081
krcp kelch repeat-containing protein 0.074
tgif1 TGFB-induced factor homeobox 1 0.063
cand1 cullin-associated and neddylation-dissociated 1 0.063
mapk3 mitogen-activated protein kinase 3 0.063
baxa bcl2-associated X protein, a 0.062
si:ch211-244o22.2 si:ch211-244o22.2 0.061
fabp7a fatty acid binding protein 7, brain, a 0.061
twist1b twist1b 0.061
slbp stem-loop binding protein 0.059
ncapg non-SMC condensin I complex, subunit G 0.059
si:ch211-173o4.2 si:ch211-173o4.2 0.059
cep55l centrosomal protein 55 like 0.057
fgf17 fibroblast growth factor 17 0.054
bmp2b bone morphogenetic protein 2b 0.054
cdc20 cell division cycle 20 homolog 0.053
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.052
depdc1a DEP domain containing 1a 0.052
melk maternal embryonic leucine zipper kinase 0.050
wnt1 wingless-type MMTV integration site family, member 1 0.049
emx2 empty spiracles homeobox 2 0.048
zgc:110113 zgc:110113 0.048
tp53 tumor protein p53 0.047
wnt5b wingless-type MMTV integration site family, member 5b 0.047
stil TAL1 (SCL) interrupting locus 0.046
cdt1 chromatin licensing and DNA replication factor 1 0.045
fgf3 fibroblast growth factor 3 0.044
LOC100536090 targeting protein for Xklp2-B-like 0.044
cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 0.043
lrp2 low density lipoprotein-related protein 2 0.042
tgfb3 transforming growth factor, beta 3 0.042
mettl2a methyltransferase like 2A 0.041
pou5f1 POU domain, class 5, transcription factor 1 0.041
zgc:92321 zgc:92321 0.041
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.040
dusp1 dual specificity phosphatase 1 0.039
sox32 SRY-box containing gene 32 0.038
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.038
wnt10a wingless-type MMTV integration site family, member 10a 0.038
sid4 secreted immunoglobulin domain 4 0.037
vcana versican a 0.036
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.036
smc1al structural maintenance of chromosomes 1A, like 0.035
pcsk5b proprotein convertase subtilisin/kexin type 5b 0.035
caprin1a cell cycle associated protein 1a 0.033
arl4ab ADP-ribosylation factor-like 4ab 0.033
id1 inhibitor of DNA binding 1 0.032
rbl1 retinoblastoma-like 1 (p107) 0.031
snrpc small nuclear ribonucleoprotein polypeptide C 0.031
wnt8b wingless-type MMTV integration site family, member 8b 0.030
lef1 lymphocyte enhancer binding factor 1 0.030
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.030
ccnt2b cyclin T2b 0.030
zgc:113210 zgc:113210 0.030
ppp2r5eb protein phosphatase 2, regulatory subunit B', epsilon isoform b 0.029
cdk2 cyclin-dependent kinase 2 0.029
ptmaa prothymosin, alpha a 0.029
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.029
szl sizzled 0.029
prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.028
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.028
fbxl14a F-box and leucine-rich repeat protein 14a 0.028
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.028
sox11a SRY-box containing gene 11a 0.028
sass6 spindle assembly 6 homolog (C. elegans) 0.028
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.027
tuba7l tubulin, alpha 7 like 0.027
crestin crestin 0.027
zar1 zygote arrest 1 0.027
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.026
pax7a paired box gene 7a 0.026
zgc:110540 zgc:110540 0.026
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
lok loki 0.963
Dref DNA replication-related element factor 0.963
Ras85D Ras oncogene at 85D 0.957
p53 CG33336 gene product from transcript CG33336-RB 0.928
phl pole hole 0.901
tefu telomere fusion 0.896
gro groucho 0.851
asp abnormal spindle 0.847
skpA CG16983 gene product from transcript CG16983-RD 0.778
CSN5 COP9 complex homolog subunit 5 0.763
mei-9 meiotic 9 0.762
pie pineapple eye 0.713
tld tolloid 0.698
Akt1 CG4006 gene product from transcript CG4006-RA 0.678
Pp2A-29B Protein phosphatase 2A at 29B 0.674
mus209 mutagen-sensitive 209 0.636
pasha partner of drosha 0.607
morgue modifier of rpr and grim, ubiquitously expressed 0.604
mus205 mutagen-sensitive 205 0.589
mus304 mutagen-sensitive 304 0.584
brm brahma 0.575
CtBP C-terminal Binding Protein 0.566
MED6 Mediator complex subunit 6 0.546
mus312 mutagen-sensitive 312 0.542
CSN3 COP9 complex homolog subunit 3 0.539
Pp1-87B Protein phosphatase 1 at 87B 0.504
fzy fizzy 0.504
Bap55 Brahma associated protein 55kD 0.501
mad2 CG17498 gene product from transcript CG17498-RA 0.480
lin lines 0.476
Kap-alpha3 karyopherin alpha3 0.468
mre11 meiotic recombination 11 0.451
CG4699 CG4699 gene product from transcript CG4699-RJ 0.449
cdm cadmus 0.440
CycB3 Cyclin B3 0.438
gish gilgamesh 0.426
sxc super sex combs 0.425
Iswi Imitation SWI 0.419
RecQ4 CG7487 gene product from transcript CG7487-RA 0.412
Sas-4 CG10061 gene product from transcript CG10061-RA 0.405
bam bag of marbles 0.401
Spc105R Spc105-related 0.399
MED17 Mediator complex subunit 17 0.398
mei-41 meiotic 41 0.398
ptc patched 0.398
Myd88 CG2078 gene product from transcript CG2078-RA 0.394
HLHm7 E(spl) region transcript m7 0.393
RanGap Ran GTPase activating protein 0.384
mus308 mutagen-sensitive 308 0.369
emb embargoed 0.368
pic piccolo 0.362
Bj1 Bj1 protein 0.357
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.351
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.351
DNApol-alpha73 DNA polymerase alpha 73kD 0.348
Fcp1 CG12252 gene product from transcript CG12252-RA 0.346
Snr1 Snf5-related 1 0.344
DNApol-alpha60 DNA polymerase alpha 60kD 0.342
dap dacapo 0.336
InR Insulin-like receptor 0.328
His2Av Histone H2A variant 0.327
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.323
RASSF8 CG5053 gene product from transcript CG5053-RA 0.320
Chc Clathrin heavy chain 0.318
imd immune deficiency 0.316
Hcf Host cell factor 0.314
wee CG4488 gene product from transcript CG4488-RA 0.314
MAGE CG10059 gene product from transcript CG10059-RA 0.298
alphaTub67C alpha-Tubulin at 67C 0.296
Caf1 Chromatin assembly factor 1 subunit 0.296
CG1792 CG1792 gene product from transcript CG1792-RA 0.292
CSN4 COP9 complex homolog subunit 4 0.289
Rpd3 CG7471 gene product from transcript CG7471-RA 0.287
CG5857 CG5857 gene product from transcript CG5857-RA 0.286
mus101 mutagen-sensitive 101 0.276
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.276
mus309 mutagen-sensitive 309 0.273
Brca2 Breast cancer 2, early onset homolog 0.269
E(spl) Enhancer of split 0.268
sno strawberry notch 0.265
Mnn1 Menin 1 0.264
Art1 Arginine methyltransferase 1 0.259
sqd squid 0.259
ncd non-claret disjunctional 0.256
Hel25E Helicase at 25E 0.254
smt3 CG4494 gene product from transcript CG4494-RA 0.254
BG4 CG12297 gene product from transcript CG12297-RA 0.253
Nup153 Nucleoporin 153 0.249
esc extra sexcombs 0.248
rod rough deal 0.239
Hdac3 Histone deacetylase 3 0.238
CycD Cyclin D 0.236
SF2 CG6987 gene product from transcript CG6987-RA 0.235
Cdk4 Cyclin-dependent kinase 4 0.229
Mcm7 Minichromosome maintenance 7 0.227
BRWD3 CG31132 gene product from transcript CG31132-RA 0.226
Pabp2 CG2163 gene product from transcript CG2163-RA 0.225
Cdc37 CG12019 gene product from transcript CG12019-RA 0.223
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.223
Klp3A Kinesin-like protein at 3A 0.223
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.999
RB1 retinoblastoma 1 0.997
BRCA1 breast cancer 1, early onset 0.994
CDK2 cyclin-dependent kinase 2 0.982
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.971
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.962
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.960
HDAC1 histone deacetylase 1 0.959
H2AFX H2A histone family, member X 0.947
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.946
COPS6 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) 0.940
SMC1A structural maintenance of chromosomes 1A 0.938
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.938
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.926
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.916
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.914
BTRC beta-transducin repeat containing 0.909
CUL1 cullin 1 0.907
MSH6 mutS homolog 6 (E. coli) 0.880
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.860
FGFR2 fibroblast growth factor receptor 2 0.859
MCM2 minichromosome maintenance complex component 2 0.848
SKP2 S-phase kinase-associated protein 2 (p45) 0.847
FGFR1 fibroblast growth factor receptor 1 0.834
CCNA2 cyclin A2 0.832
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.829
CDC25A cell division cycle 25 homolog A (S. pombe) 0.822
MDC1 mediator of DNA-damage checkpoint 1 0.811
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.806
BCL2 B-cell CLL/lymphoma 2 0.805
RBL1 retinoblastoma-like 1 (p107) 0.804
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.798
BLM Bloom syndrome, RecQ helicase-like 0.780
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.774
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.767
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.755
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.753
XIAP X-linked inhibitor of apoptosis 0.747
PLK1 polo-like kinase 1 0.744
MCM7 minichromosome maintenance complex component 7 0.734
TOP2A topoisomerase (DNA) II alpha 170kDa 0.714
COPS4 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) 0.681
RAD21 RAD21 homolog (S. pombe) 0.668
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.666
AR androgen receptor 0.665
CUL2 cullin 2 0.640
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.630
EP300 E1A binding protein p300 0.626
SMAD2 SMAD family member 2 0.616
CREBBP CREB binding protein 0.613
NBN nibrin 0.602
CCNB1 cyclin B1 0.602
ATR ataxia telangiectasia and Rad3 related 0.600
E2F7 E2F transcription factor 7 0.588
CCNE1 cyclin E1 0.584
THOC4 THO complex 4 0.577
CDK1 cyclin-dependent kinase 1 0.577
SMC4 structural maintenance of chromosomes 4 0.575
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.570
DOT1L DOT1-like, histone H3 methyltransferase (S. cerevisiae) 0.567
RFWD2 ring finger and WD repeat domain 2 0.547
FBXW11 F-box and WD repeat domain containing 11 0.544
RAD50 RAD50 homolog (S. cerevisiae) 0.539
ATM ataxia telangiectasia mutated 0.532
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.527
HDAC2 histone deacetylase 2 0.524
THOC2 THO complex 2 0.516
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.514
SKP1 S-phase kinase-associated protein 1 0.511
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.508
WRN Werner syndrome, RecQ helicase-like 0.498
JUN jun proto-oncogene 0.493
NCAPG non-SMC condensin I complex, subunit G 0.483
TOP1 topoisomerase (DNA) I 0.457
UBE2D1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.456
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.455
TOLLIP toll interacting protein 0.446
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.446
PARP1 poly (ADP-ribose) polymerase 1 0.446
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.445
E2F1 E2F transcription factor 1 0.443
PAX3 paired box 3 0.443
CLSPN claspin 0.442
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.437
STK3 serine/threonine kinase 3 0.434
TOPBP1 topoisomerase (DNA) II binding protein 1 0.434
KAT2B K(lysine) acetyltransferase 2B 0.433
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.427
CCND1 cyclin D1 0.424
ORC2 origin recognition complex, subunit 2 0.423
SMC2 structural maintenance of chromosomes 2 0.418
CDK8 cyclin-dependent kinase 8 0.416
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.414
CUL4A cullin 4A 0.400
MED1 mediator complex subunit 1 0.395
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.391
AURKB aurora kinase B 0.382
BCL2L1 BCL2-like 1 0.378
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.371
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Rb1 retinoblastoma 1 0.969
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.932
Brca1 breast cancer 1 0.914
Mdm2 transformed mouse 3T3 cell double minute 2 0.860
Shh sonic hedgehog 0.741
Hells helicase, lymphoid specific 0.676
Ctnnb1 catenin (cadherin associated protein), beta 1 0.644
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.631
Brca2 breast cancer 2 0.590
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.569
Mdm4 transformed mouse 3T3 cell double minute 4 0.556
Rara retinoic acid receptor, alpha 0.475
Pten phosphatase and tensin homolog 0.451
Cdk1 cyclin-dependent kinase 1 0.448
Smc1a structural maintenance of chromosomes 1A 0.441
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.438
Bmp4 bone morphogenetic protein 4 0.423
Rpgrip1l Rpgrip1-like 0.394
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.377
Rbl1 retinoblastoma-like 1 (p107) 0.351
Smad4 MAD homolog 4 (Drosophila) 0.350
Rnf2 ring finger protein 2 0.340
Bax BCL2-associated X protein 0.334
Atm ataxia telangiectasia mutated homolog (human) 0.333
Arid1b AT rich interactive domain 1B (SWI-like) 0.318
Sae1 SUMO1 activating enzyme subunit 1 0.311
Ccne1 cyclin E1 0.310
Fgfr1 fibroblast growth factor receptor 1 0.309
E2f1 E2F transcription factor 1 0.308
Daxx Fas death domain-associated protein 0.299
Gtse1 G two S phase expressed protein 1 0.286
Gli3 GLI-Kruppel family member GLI3 0.284
Msh2 mutS homolog 2 (E. coli) 0.281
Tcf3 transcription factor 3 0.278
Skil SKI-like 0.278
Cdk2 cyclin-dependent kinase 2 0.275
Gps1 G protein pathway suppressor 1 0.268
Aurka aurora kinase A 0.264
Nbn nibrin 0.262
Fgfr2 fibroblast growth factor receptor 2 0.261
Nde1 nuclear distribution gene E homolog 1 (A nidulans) 0.228
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.207
Rbl2 retinoblastoma-like 2 0.197
Apc adenomatosis polyposis coli 0.193
Kif2c kinesin family member 2C 0.192
Ptch1 patched homolog 1 0.192
Arid1a AT rich interactive domain 1A (SWI-like) 0.192
Sufu suppressor of fused homolog (Drosophila) 0.187
Ccna2 cyclin A2 0.183
Ccnb1 cyclin B1 0.181
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.180
Cd80 CD80 antigen 0.179
Haus6 HAUS augmin-like complex, subunit 6 0.179
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.178
Setdb1 SET domain, bifurcated 1 0.175
Prc1 protein regulator of cytokinesis 1 0.173
Tcf19 transcription factor 19 0.169
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.164
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.161
Efnb2 ephrin B2 0.159
Smc2 structural maintenance of chromosomes 2 0.157
Mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) 0.156
Cenpe centromere protein E 0.156
Pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.154
Cenpk centromere protein K 0.153
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.152
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.152
Dtl denticleless homolog (Drosophila) 0.149
Ruvbl2 RuvB-like protein 2 0.147
Egr2 early growth response 2 0.147
Gpi1 glucose phosphate isomerase 1 0.147
Lin9 lin-9 homolog (C. elegans) 0.145
Brd4 bromodomain containing 4 0.143
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.141
Kif20a kinesin family member 20A 0.137
Mis18bp1 MIS18 binding protein 1 0.137
Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.137
Smc3 structural maintenace of chromosomes 3 0.131
Gli2 GLI-Kruppel family member GLI2 0.131
Meox2 mesenchyme homeobox 2 0.130
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.129
Ncoa3 nuclear receptor coactivator 3 0.122
Plk4 polo-like kinase 4 (Drosophila) 0.121
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.121
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.121
Sox9 SRY-box containing gene 9 0.120
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.120
Aurkb aurora kinase B 0.119
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.114
Hdac2 histone deacetylase 2 0.112
Ssna1 Sjogren's syndrome nuclear autoantigen 1 0.111
Kif11 kinesin family member 11 0.109
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.109
Birc5 baculoviral IAP repeat-containing 5 0.109
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.108
Arpc4 actin related protein 2/3 complex, subunit 4 0.108
Rpa1 replication protein A1 0.106
Ccnf cyclin F 0.106
Foxc1 forkhead box C1 0.106
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism