The network for 'pyridine nucleotide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pyridine nucleotide metabolic process

The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
TAL1 Tal1p 0.894
TNA1 Tna1p 0.735
GND2 Gnd2p 0.660
ADH3 Adh3p 0.634
SOL1 Sol1p 0.634
TKL2 Tkl2p 0.472
YJL068C hypothetical protein 0.464
ALD6 Ald6p 0.428
YHR112C hypothetical protein 0.419
HXK2 Hxk2p 0.367
GND1 Gnd1p 0.359
LSC1 Lsc1p 0.359
PNC1 Pnc1p 0.359
YEF1 Yef1p 0.346
IDH2 Idh2p 0.328
ALD4 Ald4p 0.320
PET9 Pet9p 0.280
MCR1 Mcr1p 0.222
GUT2 Gut2p 0.221
UTR1 Utr1p 0.218
BNA5 Bna5p 0.213
BDH1 Bdh1p 0.187
PMI40 Pmi40p 0.185
MDH1 Mdh1p 0.183
YJL118W hypothetical protein 0.152
YCL042W hypothetical protein 0.146
SUI2 Sui2p 0.135
FBA1 Fba1p 0.135
TAX4 Tax4p 0.130
GPM2 Gpm2p 0.130
WWM1 Wwm1p 0.126
SPE3 Spe3p 0.126
YKR070W hypothetical protein 0.125
SOL3 Sol3p 0.121
GLO1 Glo1p 0.116
ADH2 Adh2p 0.114
PNS1 Pns1p 0.111
CTT1 Ctt1p 0.109
AIM45 Aim45p 0.108
PDC1 Pdc1p 0.104
ADH5 Adh5p 0.103
IMD2 Imd2p 0.098
YPR1 Ypr1p 0.098
YGR250C hypothetical protein 0.097
CAR2 Car2p 0.095
UGA1 Uga1p 0.094
HAL1 Hal1p 0.092
BNA6 Bna6p 0.091
CPR6 Cpr6p 0.088
TSA2 Tsa2p 0.088
SHE2 She2p 0.086
YPR063C hypothetical protein 0.086
NDE1 Nde1p 0.086
YIH1 Yih1p 0.084
HAP4 Hap4p 0.084
URA6 Ura6p 0.084
YPR172W hypothetical protein 0.084
MDH2 Mdh2p 0.083
HEM15 Hem15p 0.082
PDC5 Pdc5p 0.081
ECM31 Ecm31p 0.079
CPR3 Cpr3p 0.074
RTC3 Rtc3p 0.072
GRE3 Gre3p 0.071
ACO1 Aco1p 0.070
SIP2 Sip2p 0.070
PYK2 Pyk2p 0.069
ENO2 Eno2p 0.068
LEU4 Leu4p 0.068
DSD1 Dsd1p 0.068
YJL218W hypothetical protein 0.067
PFK2 Pfk2p 0.067
ECM4 Ecm4p 0.067
NQM1 Nqm1p 0.065
GCY1 Gcy1p 0.065
TFS1 Tfs1p 0.064
BNA1 Bna1p 0.063
FDC1 Fdc1p 0.062
PRS2 Prs2p 0.062
PUS6 Pus6p 0.061
INM2 Inm2p 0.060
CWP1 Cwp1p 0.059
MVD1 Mvd1p 0.059
HOR2 Hor2p 0.059
HBT1 Hbt1p 0.059
PDI1 Pdi1p 0.059
DLD1 Dld1p 0.058
HUT1 Hut1p 0.057
YGR001C hypothetical protein 0.057
NIT3 Nit3p 0.056
TRR1 Trr1p 0.055
IRC7 Irc7p 0.055
SOL2 Sol2p 0.055
GAD1 Gad1p 0.054
COA3 Coa3p 0.054
ABZ2 Abz2p 0.053
PMT3 Pmt3p 0.053
HOT13 Hot13p 0.053
YLR264C-A hypothetical protein 0.052
YPL088W hypothetical protein 0.052
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
PyK Pyruvate kinase 0.559
Got2 Glutamate oxaloacetate transaminase 2 0.521
Eno Enolase 0.518
Fdh Formaldehyde dehydrogenase 0.294
CG7920 CG7920 gene product from transcript CG7920-RA 0.263
Idh Isocitrate dehydrogenase 0.256
Pgd Phosphogluconate dehydrogenase 0.244
skap skpA associated protein 0.226
Acon Aconitase 0.223
CG42672 CG42672 gene product from transcript CG42672-RD 0.130
CG30410 CG30410 gene product from transcript CG30410-RB 0.127
Aldh Aldehyde dehydrogenase 0.113
CG6439 CG6439 gene product from transcript CG6439-RA 0.107
Aprt Adenine phosphoribosyltransferase 0.102
Pgi Phosphoglucose isomerase 0.100
CG3835 CG3835 gene product from transcript CG3835-RB 0.096
CG13474 CG13474 gene product from transcript CG13474-RA 0.084
Argk Arginine kinase 0.077
ND75 NADH:ubiquinone reductase 75kD subunit precursor 0.076
CG4390 CG4390 gene product from transcript CG4390-RB 0.073
vig vasa intronic gene 0.073
CG12992 CG12992 gene product from transcript CG12992-RB 0.070
CG5793 CG5793 gene product from transcript CG5793-RA 0.065
CG11876 CG11876 gene product from transcript CG11876-RA 0.060
regucalcin CG1803 gene product from transcript CG1803-RA 0.056
l(1)G0334 lethal (1) G0334 0.053
Zw Zwischenferment 0.047
CG10932 CG10932 gene product from transcript CG10932-RA 0.046
aay astray 0.046
Pgm Phosphogluconate mutase 0.046
Oat Ornithine aminotransferase precursor 0.046
CG3902 CG3902 gene product from transcript CG3902-RA 0.045
Mpcp Mitochondrial phosphate carrier protein 0.044
CG5261 CG5261 gene product from transcript CG5261-RB 0.042
ald altered disjunction 0.040
CG3662 CG3662 gene product from transcript CG3662-RB 0.040
Nc73EF Neural conserved at 73EF 0.039
CG18745 CG18745 gene product from transcript CG18745-RA 0.038
Ef1gamma CG11901 gene product from transcript CG11901-RC 0.038
CG14290 CG14290 gene product from transcript CG14290-RB 0.037
CG6776 CG6776 gene product from transcript CG6776-RA 0.034
CG6332 CG6332 gene product from transcript CG6332-RB 0.033
CG14204 CG14204 gene product from transcript CG14204-RA 0.033
CG16719 CG16719 gene product from transcript CG16719-RA 0.033
CG3731 CG3731 gene product from transcript CG3731-RA 0.032
Men Malic enzyme 0.032
ssp5 short spindle 5 0.031
haf hattifattener 0.031
CG30324 CG30324 gene product from transcript CG30324-RA 0.030
CG6783 CG6783 gene product from transcript CG6783-RC 0.030
CG7834 CG7834 gene product from transcript CG7834-RA 0.029
l(1)G0156 lethal (1) G0156 0.029
PHGPx CG12013 gene product from transcript CG12013-RC 0.028
CG13747 CG13747 gene product from transcript CG13747-RA 0.027
CG17597 CG17597 gene product from transcript CG17597-RA 0.027
CG5059 CG5059 gene product from transcript CG5059-RD 0.027
CG17083 CG17083 gene product from transcript CG17083-RA 0.027
CG1707 CG1707 gene product from transcript CG1707-RA 0.027
CG5214 CG5214 gene product from transcript CG5214-RA 0.026
CG13989 CG13989 gene product from transcript CG13989-RA 0.026
CG14740 CG14740 gene product from transcript CG14740-RA 0.026
mei-217 CG33935 gene product from transcript CG33935-RC 0.026
CG16926 CG16926 gene product from transcript CG16926-RA 0.025
CG5966 CG5966 gene product from transcript CG5966-RA 0.025
CG9577 CG9577 gene product from transcript CG9577-RA 0.025
Ssadh Succinic semialdehyde dehydrogenase 0.025
CG4598 CG4598 gene product from transcript CG4598-RA 0.024
CG31802 CG31802 gene product from transcript CG31802-RA 0.024
CG4169 CG4169 gene product from transcript CG4169-RA 0.024
CG3011 CG3011 gene product from transcript CG3011-RA 0.023
Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D 0.023
CG9232 CG9232 gene product from transcript CG9232-RA 0.023
CG15093 CG15093 gene product from transcript CG15093-RB 0.023
CG10075 CG10075 gene product from transcript CG10075-RA 0.023
yellow-g2 CG13804 gene product from transcript CG13804-RA 0.023
CG14260 CG14260 gene product from transcript CG14260-RA 0.023
granny-smith granny smith 0.023
Prosbeta5R Proteasome beta5R subunit 0.022
CG11196 CG11196 gene product from transcript CG11196-RA 0.022
CG5288 CG5288 gene product from transcript CG5288-RA 0.021
HisCl1 Histamine-gated chloride channel subunit 1 0.021
CG13868 CG13868 gene product from transcript CG13868-RA 0.021
eIF4E-4 CG10124 gene product from transcript CG10124-RA 0.021
CG10749 CG10749 gene product from transcript CG10749-RA 0.021
CG14402 CG14402 gene product from transcript CG14402-RA 0.021
CG3609 CG3609 gene product from transcript CG3609-RA 0.021
CG30178 CG30178 gene product from transcript CG30178-RA 0.020
Ant2 Adenine nucleotide translocase 2 0.020
ymp yellow-emperor 0.020
CG33138 CG33138 gene product from transcript CG33138-RA 0.020
yip2 yippee interacting protein 2 0.020
CG7557 CG7557 gene product from transcript CG7557-RA 0.020
CG15483 CG15483 gene product from transcript CG15483-RA 0.020
Smg5 CG8954 gene product from transcript CG8954-RA 0.020
nvy nervy 0.020
CG8417 CG8417 gene product from transcript CG8417-RA 0.020
Glut1 Glucose transporter 1 0.020
Tsp33B Tetraspanin 33B 0.019
CG5458 CG5458 gene product from transcript CG5458-RA 0.019
Lasp CG3849 gene product from transcript CG3849-RB 0.019
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Homo sapiens
Name Description Probability Func Analog Organism
ENO1 enolase 1, (alpha) 0.435
TPI1 triosephosphate isomerase 1 0.267
ALDOA aldolase A, fructose-bisphosphate 0.222
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.221
PGK1 phosphoglycerate kinase 1 0.211
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.204
GPI glucose-6-phosphate isomerase 0.200
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.134
ND1 NADH dehydrogenase, subunit 1 (complex I) 0.129
TKT transketolase 0.108
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.082
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.066
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 0.058
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.055
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.050
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.047
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.044
BBS1 Bardet-Biedl syndrome 1 0.044
PTN pleiotrophin 0.041
LDHA lactate dehydrogenase A 0.035
GOT1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 0.033
AGXT2 alanine--glyoxylate aminotransferase 2 0.032
ACO2 aconitase 2, mitochondrial 0.031
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.027
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.026
GLA galactosidase, alpha 0.026
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.025
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.022
PPIF peptidylprolyl isomerase F 0.022
CYC1 cytochrome c-1 0.019
TXN2 thioredoxin 2 0.018
HSPB1 heat shock 27kDa protein 1 0.018
ETFB electron-transfer-flavoprotein, beta polypeptide 0.018
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.017
AGPS alkylglycerone phosphate synthase 0.016
TALDO1 transaldolase 1 0.016
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.016
ECHDC1 enoyl CoA hydratase domain containing 1 0.015
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.015
GPX4 glutathione peroxidase 4 (phospholipid hydroperoxidase) 0.014
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.014
PKM2 pyruvate kinase, muscle 0.014
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.014
C9orf16 chromosome 9 open reading frame 16 0.013
IDE insulin-degrading enzyme 0.013
TSPO translocator protein (18kDa) 0.013
NFIL3 nuclear factor, interleukin 3 regulated 0.013
FTL ferritin, light polypeptide 0.012
BCKDK branched chain ketoacid dehydrogenase kinase 0.012
PGD phosphogluconate dehydrogenase 0.012
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.012
ECI1 enoyl-CoA delta isomerase 1 0.011
GCH1 GTP cyclohydrolase 1 0.011
CAPNS1 calpain, small subunit 1 0.011
LOC729020 rcRPE 0.011
POR P450 (cytochrome) oxidoreductase 0.011
SOD2 superoxide dismutase 2, mitochondrial 0.010
IFITM3 interferon induced transmembrane protein 3 (1-8U) 0.010
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.010
HCCS holocytochrome c synthase 0.010
PEMT phosphatidylethanolamine N-methyltransferase 0.010
BBS7 Bardet-Biedl syndrome 7 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Pnp2 purine-nucleoside phosphorylase 2 0.549
Gpi1 glucose phosphate isomerase 1 0.293
Aco2 aconitase 2, mitochondrial 0.157
Cs citrate synthase 0.108
Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.076
Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 0.068
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 0.063
Pgk1 phosphoglycerate kinase 1 0.060
Pgd phosphogluconate dehydrogenase 0.057
Gsta3 glutathione S-transferase, alpha 3 0.046
Aldoa aldolase A, fructose-bisphosphate 0.043
Gm5506 predicted gene 5506 0.042
Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 0.041
Inmt indolethylamine N-methyltransferase 0.040
Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 0.039
Ndufs7 NADH dehydrogenase (ubiquinone) Fe-S protein 7 0.037
Pkm2 pyruvate kinase, muscle 0.032
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.031
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.031
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.031
Cyc1 cytochrome c-1 0.031
Ces1d carboxylesterase 1D 0.030
Adh1 alcohol dehydrogenase 1 (class I) 0.030
Ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.029
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.026
Mdh2 malate dehydrogenase 2, NAD (mitochondrial) 0.025
Fmo5 flavin containing monooxygenase 5 0.025
Taldo1 transaldolase 1 0.023
Ndufs2 NADH dehydrogenase (ubiquinone) Fe-S protein 2 0.022
Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 0.022
Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 0.022
Ldha lactate dehydrogenase A 0.021
Pfkl phosphofructokinase, liver, B-type 0.020
Tkt transketolase 0.020
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.018
Immt inner membrane protein, mitochondrial 0.017
Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 0.016
Sepn1 selenoprotein N, 1 0.016
Gsr glutathione reductase 0.016
Gstm1 glutathione S-transferase, mu 1 0.016
Sirt3 sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae) 0.016
Aox1 aldehyde oxidase 1 0.016
Fh1 fumarate hydratase 1 0.015
G6pdx glucose-6-phosphate dehydrogenase X-linked 0.015
Fabp1 fatty acid binding protein 1, liver 0.014
Thrsp thyroid hormone responsive SPOT14 homolog (Rattus) 0.014
Dpep1 dipeptidase 1 (renal) 0.013
Pdha1 pyruvate dehydrogenase E1 alpha 1 0.013
Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.013
Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.013
H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.013
Rbp4 retinol binding protein 4, plasma 0.012
Ndufa10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10 0.012
Got1 glutamate oxaloacetate transaminase 1, soluble 0.012
Trap1 TNF receptor-associated protein 1 0.011
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.011
Fasn fatty acid synthase 0.011
Gckr glucokinase regulatory protein 0.011
Acsl1 acyl-CoA synthetase long-chain family member 1 0.011
Fmo1 flavin containing monooxygenase 1 0.011
Hadh hydroxyacyl-Coenzyme A dehydrogenase 0.011
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.010
Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 0.010
Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.010
Vdac2 voltage-dependent anion channel 2 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tpi1 triosephosphate isomerase 1 0.241
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.158
LOC100363662 6-phosphogluconate dehydrogenase, decarboxylating-like 0.131
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.098
Pgk1 phosphoglycerate kinase 1 0.089
Prdx3 peroxiredoxin 3 0.085
Mdh2 malate dehydrogenase 2, NAD (mitochondrial) 0.066
Atp5c1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.065
Eno1 enolase 1, (alpha) 0.046
Tufm Tu translation elongation factor, mitochondrial 0.044
Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.041
Dnase1l3 deoxyribonuclease 1-like 3 0.040
Aco2 aconitase 2, mitochondrial 0.038
Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.034
Fh1 fumarate hydratase 1 0.030
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.025
Got2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) 0.025
Fmo3 flavin containing monooxygenase 3 0.023
Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.020
Tkt transketolase 0.019
Mtch2 mitochondrial carrier homolog 2 (C. elegans) 0.019
Galm galactose mutarotase (aldose 1-epimerase) 0.017
Otc ornithine carbamoyltransferase 0.016
Kynu kynureninase (L-kynurenine hydrolase) 0.016
Ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.016
Timm17a translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.016
Auh AU RNA binding protein/enoyl-coenzyme A hydratase 0.016
Spp2 secreted phosphoprotein 2 0.015
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.014
Fasn fatty acid synthase 0.013
Slc25a39 solute carrier family 25, member 39 0.013
Alas1 aminolevulinate, delta-, synthase 1 0.013
Mfn2 mitofusin 2 0.013
Acads acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain 0.013
Acsm5 acyl-CoA synthetase medium-chain family member 5 0.013
Vdac1 voltage-dependent anion channel 1 0.012
Nmt1 N-myristoyltransferase 1 0.012
Cox5a cytochrome c oxidase, subunit Va 0.012
Pgm1 phosphoglucomutase 1 0.012
Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) 0.012
Hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit 0.012
Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) 0.012
Trap1 TNF receptor-associated protein 1 0.012
Suclg1 succinate-CoA ligase, alpha subunit 0.012
Syap1 synapse associated protein 1 0.011
Oplah 5-oxoprolinase (ATP-hydrolysing) 0.011
Dhcr7 7-dehydrocholesterol reductase 0.011
Uqcrc2 ubiquinol cytochrome c reductase core protein 2 0.011
Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 0.011
Dlat dihydrolipoamide S-acetyltransferase 0.011
Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 0.011
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.011
LOC100366121 rCG29408-like 0.011
Mosc1 MOCO sulphurase C-terminal domain containing 1 0.011
Pkm2 pyruvate kinase, muscle 0.011
Got1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 0.011
Gstt3 glutathione S-transferase, theta 3 0.010
Aldh16a1 aldehyde dehydrogenase 16 family, member A1 0.010
Leng4 leukocyte receptor cluster (LRC) member 4 0.010
Pdhb pyruvate dehydrogenase (lipoamide) beta 0.010
Gnmt glycine N-methyltransferase 0.010