The network for 'regulation of dna templated transcription initiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of dna templated transcription initiation

Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.

Name Description Probability Func Analog Organism
SPT16 Spt16p 0.820
NGG1 Ngg1p 0.362
SPT5 Spt5p 0.300
RPN2 Rpn2p 0.283
RPT6 Rpt6p 0.267
RPN1 Rpn1p 0.232
CHD1 Chd1p 0.227
CTR9 Ctr9p 0.197
MOT1 Mot1p 0.191
RSC4 Rsc4p 0.175
SPT6 Spt6p 0.170
RPT2 Rpt2p 0.153
RTF1 Rtf1p 0.147
RPN6 Rpn6p 0.119
RPT1 Rpt1p 0.118
TRA1 Tra1p 0.111
RPT4 Rpt4p 0.108
TAF6 Taf6p 0.106
BUR6 Bur6p 0.103
RFA1 Rfa1p 0.101
SKI3 Ski3p 0.089
RPN9 Rpn9p 0.079
SET2 Set2p 0.075
RPN7 Rpn7p 0.070
TAF12 Taf12p 0.064
TIF4632 Tif4632p 0.060
LSM4 Lsm4p 0.059
SUS1 Sus1p 0.058
HHT1 Hht1p 0.057
RAD23 Rad23p 0.057
CKA1 Cka1p 0.056
CKB1 Ckb1p 0.051
POB3 Pob3p 0.050
DCP1 Dcp1p 0.049
ADA2 Ada2p 0.045
IOC3 Ioc3p 0.045
WWM1 Wwm1p 0.043
INO80 Ino80p 0.042
SRD1 Srd1p 0.041
TAF5 Taf5p 0.040
ECM29 Ecm29p 0.040
LEU2 Leu2p 0.039
YLR264C-A hypothetical protein 0.038
TFA1 Tfa1p 0.037
RSC8 Rsc8p 0.037
YLR162W hypothetical protein 0.035
TFG1 Tfg1p 0.035
YOL038C-A hypothetical protein 0.035
STH1 Sth1p 0.035
RPN3 Rpn3p 0.034
HXT3 Hxt3p 0.033
BEM2 Bem2p 0.033
ESF1 Esf1p 0.032
YIL151C hypothetical protein 0.032
MF(ALPHA)2 Mf(alpha)2p 0.032
TAF10 Taf10p 0.032
MER1 Mer1p 0.032
SWI1 Swi1p 0.032
ARP10 Arp10p 0.031
SPL2 Spl2p 0.031
RPN10 Rpn10p 0.030
ARG8 Arg8p 0.030
URA3 Ura3p 0.030
RPT5 Rpt5p 0.030
SGT2 Sgt2p 0.030
YLR419W hypothetical protein 0.029
DLS1 Dls1p 0.029
CHA1 Cha1p 0.028
SEM1 Sem1p 0.028
YGR017W hypothetical protein 0.028
YPR157W hypothetical protein 0.028
YAR068W hypothetical protein 0.028
YLR042C hypothetical protein 0.027
TFG2 Tfg2p 0.027
HO Hop 0.027
MF(ALPHA)1 Mf(alpha)1p 0.027
PRS2 Prs2p 0.026
ATP6 Atp6p 0.026
ITC1 Itc1p 0.026
SCM4 Scm4p 0.025
MCM6 Mcm6p 0.025
HPF1 Hpf1p 0.025
YBR013C hypothetical protein 0.024
CUP1-1 Cup1-1p 0.024
AUA1 Aua1p 0.024
IOC2 Ioc2p 0.024
FMT1 Fmt1p 0.024
AQY2 Aqy2p 0.024
ZPS1 Zps1p 0.024
PHM6 Phm6p 0.023
REB1 Reb1p 0.023
RSC58 Rsc58p 0.023
YOL013W-A hypothetical protein 0.023
PRE10 Pre10p 0.022
DIC1 Dic1p 0.022
TYE7 Tye7p 0.022
LEO1 Leo1p 0.021
OPT2 Opt2p 0.021
RCO1 Rco1p 0.021
SPT15 Spt15p 0.021
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
mRpL49 mitochondrial ribosomal protein L49 0.011
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Homo sapiens
Name Description Probability Func Analog Organism
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.616
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.451
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.400
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.269
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.246
TBP TATA box binding protein 0.238
SMAD4 SMAD family member 4 0.220
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.205
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.175
NCOA6 nuclear receptor coactivator 6 0.155
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.144
SP1 Sp1 transcription factor 0.102
DCP1A DCP1 decapping enzyme homolog A (S. cerevisiae) 0.099
SKIL SKI-like oncogene 0.092
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.084
TBX5 T-box 5 0.082
CTR9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.080
SMC1A structural maintenance of chromosomes 1A 0.070
HMGB2 high mobility group box 2 0.067
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.064
CREBBP CREB binding protein 0.060
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.055
SMC3 structural maintenance of chromosomes 3 0.054
RAD21 RAD21 homolog (S. pombe) 0.046
NCOA1 nuclear receptor coactivator 1 0.044
NCOR1 nuclear receptor corepressor 1 0.042
MED25 mediator complex subunit 25 0.040
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.040
RB1 retinoblastoma 1 0.038
SSRP1 structure specific recognition protein 1 0.037
ESR1 estrogen receptor 1 0.037
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.037
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.035
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.035
SMAD9 SMAD family member 9 0.033
RBM25 RNA binding motif protein 25 0.030
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.029
MKL1 megakaryoblastic leukemia (translocation) 1 0.029
RXRA retinoid X receptor, alpha 0.029
ARNT aryl hydrocarbon receptor nuclear translocator 0.025
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 0.024
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.023
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.021
NCOR2 nuclear receptor corepressor 2 0.021
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.020
HMGA1 high mobility group AT-hook 1 0.020
SIRT1 sirtuin 1 0.020
NUP153 nucleoporin 153kDa 0.019
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.019
NBN nibrin 0.018
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.017
HMGB1 high mobility group box 1 0.017
DEK DEK oncogene 0.016
HDAC3 histone deacetylase 3 0.016
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.015
TRIM33 tripartite motif containing 33 0.015
SMAD2 SMAD family member 2 0.015
RSRC2 arginine/serine-rich coiled-coil 2 0.014
DCP1B DCP1 decapping enzyme homolog B (S. cerevisiae) 0.014
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.014
SNW1 SNW domain containing 1 0.014
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.014
HTT huntingtin 0.013
KAT2B K(lysine) acetyltransferase 2B 0.013
PSIP1 PC4 and SFRS1 interacting protein 1 0.013
WAPAL wings apart-like homolog (Drosophila) 0.013
SFPQ splicing factor proline/glutamine-rich 0.012
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.012
E2F3 E2F transcription factor 3 0.012
LBR lamin B receptor 0.012
PRPF4B PRP4 pre-mRNA processing factor 4 homolog B (yeast) 0.012
BCLAF1 BCL2-associated transcription factor 1 0.012
SMAD3 SMAD family member 3 0.011
KLHL24 kelch-like 24 (Drosophila) 0.011
C10orf18 chromosome 10 open reading frame 18 0.011
ZNF518A zinc finger protein 518A 0.011
CHD1 chromodomain helicase DNA binding protein 1 0.011
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.011
SCAF8 SR-related CTD-associated factor 8 0.011
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 0.694
Fgf8 fibroblast growth factor 8 0.659
Shh sonic hedgehog 0.561
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.512
Gata4 GATA binding protein 4 0.506
Gli2 GLI-Kruppel family member GLI2 0.355
Wnt3a wingless-related MMTV integration site 3A 0.323
Gli3 GLI-Kruppel family member GLI3 0.295
Pax8 paired box gene 8 0.285
Hand2 heart and neural crest derivatives expressed transcript 2 0.274
Sox9 SRY-box containing gene 9 0.263
Nog noggin 0.253
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.244
Rxra retinoid X receptor alpha 0.228
Foxc1 forkhead box C1 0.175
Lhx1 LIM homeobox protein 1 0.167
Hand1 heart and neural crest derivatives expressed transcript 1 0.160
Vax1 ventral anterior homeobox containing gene 1 0.143
Fgfr2 fibroblast growth factor receptor 2 0.140
Tbx1 T-box 1 0.114
Wnt4 wingless-related MMTV integration site 4 0.110
Barx2 BarH-like homeobox 2 0.104
Pitx2 paired-like homeodomain transcription factor 2 0.098
Hoxd13 homeobox D13 0.090
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.087
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.087
Nkx6-1 NK6 homeobox 1 0.087
Rarg retinoic acid receptor, gamma 0.083
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.079
Rarb retinoic acid receptor, beta 0.077
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.075
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.068
Usp18 ubiquitin specific peptidase 18 0.065
Wnt6 wingless-related MMTV integration site 6 0.062
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.061
Hoxa13 homeobox A13 0.059
Hoxd11 homeobox D11 0.058
Stat2 signal transducer and activator of transcription 2 0.054
Lhx3 LIM homeobox protein 3 0.053
Gdnf glial cell line derived neurotrophic factor 0.049
Ctnnb1 catenin (cadherin associated protein), beta 1 0.047
Gata6 GATA binding protein 6 0.047
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.046
Tbx3 T-box 3 0.045
Scaf11 SR-related CTD-associated factor 11 0.044
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.042
Mesp1 mesoderm posterior 1 0.042
Gata5 GATA binding protein 5 0.042
Trp63 transformation related protein 63 0.040
Tbx5 T-box 5 0.040
Emx2 empty spiracles homolog 2 (Drosophila) 0.040
Barx1 BarH-like homeobox 1 0.039
T brachyury 0.039
Foxc2 forkhead box C2 0.039
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.038
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.038
Emx1 empty spiracles homolog 1 (Drosophila) 0.038
Uba7 ubiquitin-like modifier activating enzyme 7 0.037
Otx2 orthodenticle homolog 2 (Drosophila) 0.037
Efna4 ephrin A4 0.036
Lmx1a LIM homeobox transcription factor 1 alpha 0.035
Tapbp TAP binding protein 0.034
En1 engrailed 1 0.034
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.033
Isg15 ISG15 ubiquitin-like modifier 0.033
Rara retinoic acid receptor, alpha 0.033
Tgfb2 transforming growth factor, beta 2 0.032
Zfpm2 zinc finger protein, multitype 2 0.032
Pax1 paired box gene 1 0.032
Otx1 orthodenticle homolog 1 (Drosophila) 0.032
Foxe1 forkhead box E1 0.032
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.031
Fgf3 fibroblast growth factor 3 0.031
Ntf3 neurotrophin 3 0.031
Wnt2b wingless related MMTV integration site 2b 0.030
Socs1 suppressor of cytokine signaling 1 0.030
Irf7 interferon regulatory factor 7 0.030
Pthlh parathyroid hormone-like peptide 0.029
Ihh Indian hedgehog 0.029
Tbx2 T-box 2 0.028
Bmp7 bone morphogenetic protein 7 0.028
Nkx3-2 NK3 homeobox 2 0.028
Pitx1 paired-like homeodomain transcription factor 1 0.027
Kl klotho 0.027
Irgm1 immunity-related GTPase family M member 1 0.027
Amh anti-Mullerian hormone 0.026
Col2a1 collagen, type II, alpha 1 0.026
Ar androgen receptor 0.026
Batf3 basic leucine zipper transcription factor, ATF-like 3 0.025
Gli1 GLI-Kruppel family member GLI1 0.025
Tcf21 transcription factor 21 0.024
Lmx1b LIM homeobox transcription factor 1 beta 0.024
Igtp interferon gamma induced GTPase 0.023
Wnt10b wingless related MMTV integration site 10b 0.023
Cdx1 caudal type homeobox 1 0.023
Hmx3 H6 homeobox 3 0.023
Bmpr1a bone morphogenetic protein receptor, type 1A 0.022
Six5 sine oculis-related homeobox 5 homolog (Drosophila) 0.022
Foxa2 forkhead box A2 0.022
Efnb2 ephrin B2 0.022
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Rattus norvegicus
Name Description Probability Func Analog Organism
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.089
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.040
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.034
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.020