The network for 'positive regulation of dna templated transcription initiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of dna templated transcription initiation

Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.

Name Description Probability Func Analog Organism
SPT16 Spt16p 0.680
RPT6 Rpt6p 0.408
RPT2 Rpt2p 0.188
RPN1 Rpn1p 0.178
RPT5 Rpt5p 0.149
RPT1 Rpt1p 0.144
RPN2 Rpn2p 0.121
RPT4 Rpt4p 0.110
WWM1 Wwm1p 0.102
NGG1 Ngg1p 0.080
TAF5 Taf5p 0.074
TRA1 Tra1p 0.069
RPN6 Rpn6p 0.066
RPN9 Rpn9p 0.055
RAD23 Rad23p 0.053
TAF12 Taf12p 0.047
RPN7 Rpn7p 0.045
HHT2 Hht2p 0.041
SPT5 Spt5p 0.039
CTR9 Ctr9p 0.036
RPN10 Rpn10p 0.035
RPT3 Rpt3p 0.033
LEU2 Leu2p 0.033
SRD1 Srd1p 0.032
YLR264C-A hypothetical protein 0.032
TAF6 Taf6p 0.031
YLR162W hypothetical protein 0.029
SWC7 Swc7p 0.028
MER1 Mer1p 0.028
YOL038C-A hypothetical protein 0.028
SUS1 Sus1p 0.028
MF(ALPHA)2 Mf(alpha)2p 0.026
ADA2 Ada2p 0.026
HXT3 Hxt3p 0.025
ARP10 Arp10p 0.025
SCD6 Scd6p 0.024
PBP1 Pbp1p 0.024
ARG8 Arg8p 0.024
HDA2 Hda2p 0.023
URA3 Ura3p 0.022
CUP1-1 Cup1-1p 0.022
YPR157W hypothetical protein 0.022
BAT2 Bat2p 0.022
MF(ALPHA)1 Mf(alpha)1p 0.022
YLR042C hypothetical protein 0.021
YAR068W hypothetical protein 0.021
SGT2 Sgt2p 0.020
ATP6 Atp6p 0.020
AUA1 Aua1p 0.020
SPL2 Spl2p 0.020
SPT8 Spt8p 0.020
YBR013C hypothetical protein 0.019
HPF1 Hpf1p 0.019
DCP1 Dcp1p 0.019
ZPS1 Zps1p 0.019
CHA1 Cha1p 0.019
POB3 Pob3p 0.019
PRS2 Prs2p 0.019
YOL013W-A hypothetical protein 0.018
PRE2 Pre2p 0.018
SCM4 Scm4p 0.018
YIR035C hypothetical protein 0.018
RPN3 Rpn3p 0.018
FMT1 Fmt1p 0.018
CRP1 Crp1p 0.018
IZH4 Izh4p 0.018
ADH2 Adh2p 0.017
CKB1 Ckb1p 0.017
DIC1 Dic1p 0.017
TAF8 Taf8p 0.017
TYE7 Tye7p 0.017
BSC1 Bsc1p 0.017
YLR363W-A hypothetical protein 0.017
TAF9 Taf9p 0.017
RRN5 Rrn5p 0.017
HO Hop 0.017
YKR075C hypothetical protein 0.016
ARR2 Arr2p 0.016
TSC3 Tsc3p 0.016
NRG2 Nrg2p 0.016
ALT2 Alt2p 0.016
RFA1 Rfa1p 0.016
YLR040C hypothetical protein 0.016
BNA4 Bna4p 0.016
YPR096C hypothetical protein 0.016
CPD1 Cpd1p 0.016
COS12 Cos12p 0.016
REE1 Ree1p 0.015
OPT2 Opt2p 0.015
RRT5 Rrt5p 0.015
YAL064W hypothetical protein 0.015
YAL037C-A hypothetical protein 0.015
YAR066W hypothetical protein 0.015
RNP1 Rnp1p 0.015
MFA2 Mfa2p 0.015
UPS3 Ups3p 0.015
PTI1 Pti1p 0.015
BIO2 Bio2p 0.015
YPL067C hypothetical protein 0.014
MET8 Met8p 0.014
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.079
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.050
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.046
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.042
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.036
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.028
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.024
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.024
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.023
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.017
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.016
TBP TATA box binding protein 0.015
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Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 0.988
Fgf8 fibroblast growth factor 8 0.977
Pax2 paired box gene 2 0.974
Gli3 GLI-Kruppel family member GLI3 0.923
Fgfr2 fibroblast growth factor receptor 2 0.679
Gli2 GLI-Kruppel family member GLI2 0.645
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.504
Sox9 SRY-box containing gene 9 0.482
Tbx1 T-box 1 0.481
Gata4 GATA binding protein 4 0.477
Rarg retinoic acid receptor, gamma 0.452
Hand2 heart and neural crest derivatives expressed transcript 2 0.443
Gdnf glial cell line derived neurotrophic factor 0.437
Hoxd11 homeobox D11 0.413
Pax8 paired box gene 8 0.409
Hoxd13 homeobox D13 0.408
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.406
Vax1 ventral anterior homeobox containing gene 1 0.403
Lhx1 LIM homeobox protein 1 0.394
Hand1 heart and neural crest derivatives expressed transcript 1 0.388
Hoxa13 homeobox A13 0.320
T brachyury 0.309
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.305
Socs1 suppressor of cytokine signaling 1 0.303
Wnt3a wingless-related MMTV integration site 3A 0.300
Nkx6-1 NK6 homeobox 1 0.287
Foxc1 forkhead box C1 0.270
Nog noggin 0.246
Wnt6 wingless-related MMTV integration site 6 0.238
Gata6 GATA binding protein 6 0.237
Hoxa1 homeobox A1 0.221
Lmx1a LIM homeobox transcription factor 1 alpha 0.203
Fgf10 fibroblast growth factor 10 0.193
Rxra retinoid X receptor alpha 0.192
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.185
Pitx2 paired-like homeodomain transcription factor 2 0.178
Rarb retinoic acid receptor, beta 0.177
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.174
Ikzf1 IKAROS family zinc finger 1 0.172
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.171
Stat2 signal transducer and activator of transcription 2 0.163
Uba7 ubiquitin-like modifier activating enzyme 7 0.159
Foxc2 forkhead box C2 0.149
Msx1 homeobox, msh-like 1 0.148
Barx2 BarH-like homeobox 2 0.148
Cd19 CD19 antigen 0.132
Mesp1 mesoderm posterior 1 0.126
Wnt4 wingless-related MMTV integration site 4 0.125
Barx1 BarH-like homeobox 1 0.124
Emx2 empty spiracles homolog 2 (Drosophila) 0.118
Foxd2 forkhead box D2 0.116
Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 0.112
Trp63 transformation related protein 63 0.111
Fgf3 fibroblast growth factor 3 0.108
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.108
Trp53 transformation related protein 53 0.107
En1 engrailed 1 0.104
Tbx3 T-box 3 0.103
Hmx3 H6 homeobox 3 0.102
Pthlh parathyroid hormone-like peptide 0.099
Pax1 paired box gene 1 0.097
Tbx2 T-box 2 0.096
Rara retinoic acid receptor, alpha 0.092
Foxn1 forkhead box N1 0.091
Twist2 twist homolog 2 (Drosophila) 0.091
Cdx1 caudal type homeobox 1 0.090
Ntf3 neurotrophin 3 0.077
Ret ret proto-oncogene 0.076
Gata5 GATA binding protein 5 0.075
Otx2 orthodenticle homolog 2 (Drosophila) 0.074
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.072
Lmx1b LIM homeobox transcription factor 1 beta 0.067
Batf3 basic leucine zipper transcription factor, ATF-like 3 0.066
Pitx3 paired-like homeodomain transcription factor 3 0.063
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.062
Otx1 orthodenticle homolog 1 (Drosophila) 0.060
Wnt2b wingless related MMTV integration site 2b 0.060
Hoxa11 homeobox A11 0.057
Gli1 GLI-Kruppel family member GLI1 0.057
Sim2 single-minded homolog 2 (Drosophila) 0.057
Ar androgen receptor 0.056
Isl1 ISL1 transcription factor, LIM/homeodomain 0.053
Wt1 Wilms tumor 1 homolog 0.052
Cd40 CD40 antigen 0.052
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.051
Smo smoothened homolog (Drosophila) 0.051
Bmp7 bone morphogenetic protein 7 0.049
Fgf15 fibroblast growth factor 15 0.048
Pou3f3 POU domain, class 3, transcription factor 3 0.048
Wnt10b wingless related MMTV integration site 10b 0.047
Hoxd3 homeobox D3 0.047
Adra2b adrenergic receptor, alpha 2b 0.046
Sfpi1 SFFV proviral integration 1 0.046
Tbx5 T-box 5 0.046
Bmp4 bone morphogenetic protein 4 0.045
Neurog1 neurogenin 1 0.045
Pitx1 paired-like homeodomain transcription factor 1 0.045
Hoxa4 homeobox A4 0.045
Lhx3 LIM homeobox protein 3 0.045
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.045
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Rattus norvegicus
Name Description Probability Func Analog Organism
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.464
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.217
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.161
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.113
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.107
Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.046
Nsfl1c NSFL1 (p97) cofactor (p47) 0.034
Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.030
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.027
Psmb5 proteasome (prosome, macropain) subunit, beta type 5 0.024
Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.019
Psmb6 proteasome (prosome, macropain) subunit, beta type 6 0.013
Dhx15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 0.012
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.011