The network for 'negative regulation of rna metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of rna metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RPD3 Rpd3p 0.999
HHF1 Hhf1p 0.998
SIR2 Sir2p 0.995
HHT1 Hht1p 0.995
SIN3 Sin3p 0.991
RAP1 Rap1p 0.989
HDA1 Hda1p 0.988
RLF2 Rlf2p 0.982
SIR4 Sir4p 0.981
CTI6 Cti6p 0.979
RXT2 Rxt2p 0.971
CTK1 Ctk1p 0.970
RCO1 Rco1p 0.966
SIN4 Sin4p 0.966
ORC2 Orc2p 0.961
YTA7 Yta7p 0.957
RTT106 Rtt106p 0.950
HAT1 Hat1p 0.949
HMO1 Hmo1p 0.947
RIF1 Rif1p 0.939
SUM1 Sum1p 0.937
SDS3 Sds3p 0.934
PHO23 Pho23p 0.905
FKH2 Fkh2p 0.899
ISW2 Isw2p 0.878
CYC8 Cyc8p 0.875
ORC5 Orc5p 0.875
RPN4 Rpn4p 0.866
GLC7 Glc7p 0.864
SET1 Set1p 0.847
ASF1 Asf1p 0.834
GBP2 Gbp2p 0.828
YAK1 Yak1p 0.818
HTB1 Htb1p 0.813
PGD1 Pgd1p 0.783
SAS2 Sas2p 0.781
ROX3 Rox3p 0.781
ADR1 Adr1p 0.772
NAT1 Nat1p 0.768
MED2 Med2p 0.766
CSE2 Cse2p 0.765
GLN3 Gln3p 0.759
ZDS1 Zds1p 0.744
HOG1 Hog1p 0.732
HIR1 Hir1p 0.714
SNT1 Snt1p 0.698
GCN5 Gcn5p 0.696
ARP4 Arp4p 0.688
CDC45 Cdc45p 0.686
SAS4 Sas4p 0.680
DOA1 Doa1p 0.680
RSC4 Rsc4p 0.679
VPS36 Vps36p 0.658
UBP8 Ubp8p 0.653
RGR1 Rgr1p 0.652
GAL11 Gal11p 0.648
SNF5 Snf5p 0.642
MET4 Met4p 0.642
BDF1 Bdf1p 0.641
DOT6 Dot6p 0.639
SPT10 Spt10p 0.639
UME1 Ume1p 0.636
ITC1 Itc1p 0.636
YCS4 Ycs4p 0.625
GCR2 Gcr2p 0.622
HCM1 Hcm1p 0.610
STM1 Stm1p 0.606
HDA3 Hda3p 0.603
ADA2 Ada2p 0.601
SWD1 Swd1p 0.598
LGE1 Lge1p 0.595
FOB1 Fob1p 0.585
DEP1 Dep1p 0.579
RTF1 Rtf1p 0.573
HRK1 Hrk1p 0.572
SSN3 Ssn3p 0.572
SET2 Set2p 0.568
SAP30 Sap30p 0.566
SIR3 Sir3p 0.550
RIM101 Rim101p 0.546
NRG1 Nrg1p 0.544
HHF2 Hhf2p 0.541
ISW1 Isw1p 0.538
CDC6 Cdc6p 0.538
MOT3 Mot3p 0.537
HAT2 Hat2p 0.534
IZH4 Izh4p 0.533
VHS1 Vhs1p 0.531
SLX5 Slx5p 0.517
AFT1 Aft1p 0.517
CCR4 Ccr4p 0.510
RLM1 Rlm1p 0.507
HTZ1 Htz1p 0.504
SPT21 Spt21p 0.503
CDC14 Cdc14p 0.499
NHP6A Nhp6ap 0.499
HTA1 Hta1p 0.484
NUT2 Nut2p 0.483
TOR1 Tor1p 0.483
CHD1 Chd1p 0.478
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.945
pha-4 Protein PHA-4 0.595
elt-6 Protein ELT-6 0.429
his-1 Protein HIS-1 0.357
rad-26 Protein RAD-26 0.285
his-68 Protein HIS-68 0.244
his-16 Protein HIS-16 0.238
let-502 Protein LET-502 0.224
lin-53 Protein LIN-53 0.193
egl-13 Protein EGL-13 0.183
mes-4 Protein MES-4 0.172
egl-46 Protein EGL-46 0.165
mat-3 Protein MAT-3 0.161
his-5 Protein HIS-5 0.156
his-31 Protein HIS-31 0.151
wrm-1 Protein WRM-1 0.150
his-64 Protein HIS-64 0.146
attf-2 Protein ATTF-2 0.146
his-61 Protein HIS-61 0.143
pry-1 Protein PRY-1 0.136
atg-2 Protein ATG-2 0.129
his-62 Protein HIS-62 0.128
his-46 Protein HIS-46 0.123
zip-7 Protein ZIP-7 0.121
unc-62 Protein UNC-62 0.121
Y17G7B.20 Protein Y17G7B.20 0.119
prp-8 Protein PRP-8 0.118
his-47 Protein HIS-47 0.114
CELE_F19F10.9 Protein F19F10.9 0.114
lin-11 Protein LIN-11 0.113
his-48 Protein HIS-48 0.109
tbx-8 Protein TBX-8 0.107
let-418 Protein LET-418 0.107
mep-1 Protein MEP-1 0.106
ran-1 Protein RAN-1 0.105
his-3 Protein HIS-3 0.104
hlh-2 Protein HLH-2 0.104
fkb-6 Protein FKB-6 0.101
aph-2 Protein APH-2 0.100
skp-1 Protein SKP-1 0.099
CELE_W03F9.10 Protein W03F9.10 0.092
lin-66 Protein LIN-66 0.092
hda-1 Protein HDA-1 0.090
ceh-38 Protein CEH-38 0.090
F39B2.1 Protein F39B2.1 0.090
his-38 Protein HIS-38 0.090
eya-1 Protein EYA-1 0.090
CELE_C12D8.1 Protein C12D8.1 0.089
lin-1 Protein LIN-1 0.085
ceh-32 Protein CEH-32 0.082
ceh-27 Protein CEH-27 0.079
egl-38 Protein EGL-38 0.078
mls-2 Protein MLS-2 0.076
his-52 Protein HIS-52 0.076
hlh-11 Protein HLH-11 0.076
csn-4 Protein CSN-4 0.074
his-30 Protein HIS-30 0.073
lin-17 Protein LIN-17 0.071
hda-3 Protein HDA-3 0.068
rsp-1 Protein RSP-1 0.067
CELE_Y41E3.11 Protein Y41E3.11 0.067
his-29 Protein HIS-29 0.067
lin-12 Protein LIN-12 0.067
T20F7.1 Protein T20F7.1 0.066
hum-5 Protein HUM-5 0.066
plc-1 Protein PLC-1 0.064
his-51 Protein HIS-51 0.063
nhr-67 Protein NHR-67 0.062
mcm-2 Protein MCM-2 0.061
his-50 Protein HIS-50 0.060
prpf-4 Protein PRPF-4 0.060
rpa-2 Protein RPA-2 0.059
T28C6.7 Protein T28C6.7 0.059
F33H2.3 Protein F33H2.3 0.059
mix-1 Protein MIX-1 0.059
his-15 Protein HIS-15 0.058
mcm-4 Protein MCM-4 0.057
his-4 Protein HIS-4 0.056
D2096.7 Protein D2096.7 0.055
bar-1 Protein BAR-1 0.054
klp-19 Protein KLP-19 0.053
dcr-1 Protein DCR-1 0.053
mrpl-18 Protein MRPL-18 0.053
T09B4.5 Protein T09B4.5 0.053
eor-1 Protein EOR-1 0.053
C27F2.8 Protein C27F2.8 0.053
pax-3 Protein PAX-3 0.053
Y42H9AR.4 Protein Y42H9AR.4 0.053
F55F8.9 Protein F55F8.9 0.052
qua-1 Protein QUA-1 0.052
hlh-1 Protein HLH-1 0.052
daf-1 Protein DAF-1 0.051
ztf-2 Protein ZTF-2 0.051
hbl-1 Protein HBL-1 0.050
frm-7 Protein FRM-7 0.050
bet-1 Protein BET-1 0.050
swsn-4 Protein SWSN-4 0.050
cpf-2 Protein CPF-2 0.050
rskn-2 Protein RSKN-2 0.050
C46F11.4 Protein C46F11.4 0.049
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Danio rerio
Name Description Probability Func Analog Organism
gli1 GLI-Kruppel family member 1 0.926
ndr2 nodal-related 2 0.917
jag2 jagged 2 0.812
lhx1a LIM homeobox 1a 0.759
mab21l2 mab-21-like 2 0.746
snai1b snail homolog 1b (Drosophila) 0.710
bmp2b bone morphogenetic protein 2b 0.666
chd chordin 0.611
fgf3 fibroblast growth factor 3 0.570
dlx2a distal-less homeobox gene 2a 0.565
gata6 GATA-binding protein 6 0.563
wt1a wilms tumor 1a 0.563
mecom MDS1 and EVI1 complex locus 0.557
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.551
sox32 SRY-box containing gene 32 0.528
hnf1ba HNF1 homeobox Ba 0.507
twist3 twist3 0.498
fsta follistatin a 0.493
lef1 lymphocyte enhancer binding factor 1 0.447
flh floating head 0.421
tll1 tolloid-like 1 0.386
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.365
per2 period homolog 2 (Drosophila) 0.357
gro1 groucho 1 0.350
pax8 paired box gene 8 0.346
fzd8a frizzled homolog 8a 0.345
foxi1 forkhead box I1 0.302
dlc deltaC 0.291
zic5 zic family member 5 (odd-paired homolog, Drosophila) 0.277
grem2 gremlin 2, cysteine knot superfamily 0.269
runx1 runt-related transcription factor 1 0.268
six3b sine oculis homeobox homolog 3b 0.257
sox19a SRY-box containing gene 19a 0.253
meis3 myeloid ecotropic viral integration site 3 0.252
isl1 islet1 0.251
tac1 tachykinin 1 0.243
pcna proliferating cell nuclear antigen 0.241
klf4a Kruppel-like transcription factor 4a 0.233
otx2 orthodenticle homolog 2 0.231
znfl2a zinc finger-like gene 2a 0.226
wnt5b wingless-type MMTV integration site family, member 5b 0.226
zic2b zic family member 2 (odd-paired homolog, Drosophila) b 0.223
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.222
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.217
vcana versican a 0.214
bmp4 bone morphogenetic protein 4 0.213
spaw southpaw 0.213
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.211
meis2.1 myeloid ecotropic viral integration site 2.1 0.210
wnt1 wingless-type MMTV integration site family, member 1 0.210
socs3a suppressor of cytokine signaling 3a 0.209
hoxb1b homeo box B1b 0.203
eomesa eomesodermin homolog a 0.202
sox9b SRY-box containing gene 9b 0.199
rorca RAR-related orphan receptor C a 0.198
lft2 lefty2 0.198
lhx5 LIM homeobox 5 0.195
pou3f2 POU class 3 homeobox 2 0.194
prox1 prospero-related homeobox gene 1 0.193
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.189
her7 hairy and enhancer of split related-7 0.188
pdlim7 PDZ and LIM domain 7 0.183
tfap2a transcription factor AP-2 alpha 0.182
cdx4 caudal type homeo box transcription factor 4 0.181
sesn1 sestrin 1 0.179
insm1b insulinoma-associated 1b 0.176
rarga retinoic acid receptor gamma a 0.174
ntla no tail a 0.170
sox1a SRY-box containing gene 1a 0.163
atoh7 atonal homolog 7 0.163
pax6a paired box gene 6a 0.163
ptf1a pancreas specific transcription factor, 1a 0.162
dct dopachrome tautomerase 0.161
hmx1 H6 homeo box 1 0.160
dlx5a distal-less homeobox gene 5a 0.158
nkx2.1a NK2 homeobox 1a 0.158
snai1a snail homolog 1a (Drosophila) 0.157
flt4 fms-related tyrosine kinase 4 0.153
neurog1 neurogenin 1 0.150
ephb3a eph receptor B3a 0.150
her1 hairy-related 1 0.148
otx1b orthodenticle homolog 1b 0.147
junb jun B proto-oncogene 0.147
pcdh8 protocadherin 8 0.146
cry3 cryptochrome 3 0.144
rarab retinoic acid receptor, alpha b 0.143
otx5 orthodenticle homolog 5 0.141
ascl1b achaete-scute complex-like 1b (Drosophila) 0.139
dusp6 dual specificity phosphatase 6 0.139
id1 inhibitor of DNA binding 1 0.139
has2 hyaluronan synthase 2 0.139
plekhg4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.135
traf4a tnf receptor-associated factor 4a 0.134
nkx2.5 NK2 transcription factor related 5 0.133
ddx39b DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b 0.132
sall1a sal-like 1a (Drosophila) 0.130
vsx1 visual system homeobox 1 homolog, chx10-like 0.130
tyr tyrosinase 0.129
hmx4 H6 family homeobox 4 0.129
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.129
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Drosophila melanogaster
Name Description Probability Func Analog Organism
gro groucho 1.000
CTCF CG8591 gene product from transcript CG8591-RA 0.999
Iswi Imitation SWI 0.999
Abd-B Abdominal B 0.998
Scm Sex comb on midleg 0.998
Su(var)205 Suppressor of variegation 205 0.998
ush u-shaped 0.996
Ubx Ultrabithorax 0.992
hep hemipterous 0.992
Snr1 Snf5-related 1 0.990
hth homothorax 0.989
tll tailless 0.988
kay kayak 0.987
Su(H) Suppressor of Hairless 0.982
His2Av Histone H2A variant 0.982
ato atonal 0.978
E(spl) Enhancer of split 0.975
dsh dishevelled 0.969
gpp grappa 0.958
Sir2 CG5216 gene product from transcript CG5216-RA 0.957
gsb gooseberry 0.954
ash1 absent, small, or homeotic discs 1 0.952
smt3 CG4494 gene product from transcript CG4494-RA 0.940
D1 D1 chromosomal protein 0.939
CtBP C-terminal Binding Protein 0.934
rin rasputin 0.928
slp1 sloppy paired 1 0.928
dco discs overgrown 0.927
bcd bicoid 0.925
ci cubitus interruptus 0.925
ara araucan 0.924
Optix CG18455 gene product from transcript CG18455-RA 0.923
emc extra macrochaetae 0.921
prd paired 0.918
Trf2 TATA box binding protein-related factor 2 0.917
spen split ends 0.912
pr-set7 CG3307 gene product from transcript CG3307-RC 0.909
mam mastermind 0.904
Kr Kruppel 0.904
Mad Mothers against dpp 0.904
nub nubbin 0.899
Pcl Polycomblike 0.891
dac dachshund 0.885
CycB Cyclin B 0.882
C15 CG7937 gene product from transcript CG7937-RA 0.882
run runt 0.876
shn schnurri 0.875
hh hedgehog 0.875
E(var)3-9 Enhancer of variegation 3-9 0.872
Pp1-87B Protein phosphatase 1 at 87B 0.871
Pka-C1 cAMP-dependent protein kinase 1 0.870
sno strawberry notch 0.864
salm spalt major 0.863
barr barren 0.862
Ten-m Tenascin major 0.859
sna snail 0.859
Dsp1 Dorsal switch protein 1 0.857
Hel25E Helicase at 25E 0.856
brk brinker 0.851
Acf1 ATP-dependent chromatin assembly factor large subunit 0.847
BEAF-32 Boundary element-associated factor of 32kD 0.845
Med Medea 0.844
aop anterior open 0.840
ey eyeless 0.833
Nf-YC Nuclear factor Y-box C 0.830
osa CG7467 gene product from transcript CG7467-RD 0.827
rept reptin 0.826
ss spineless 0.825
InR Insulin-like receptor 0.822
abd-A abdominal A 0.819
sxc super sex combs 0.817
eya eyes absent 0.815
HLHm7 E(spl) region transcript m7 0.814
eyg eyegone 0.805
al aristaless 0.802
Eip63E Ecdysone-induced protein 63E 0.795
sd scalloped 0.792
pb proboscipedia 0.791
Doc2 Dorsocross2 0.785
inv invected 0.777
odd odd skipped 0.773
p53 CG33336 gene product from transcript CG33336-RB 0.772
trx trithorax 0.767
brat brain tumor 0.766
Sce Sex combs extra 0.761
vg vestigial 0.758
Pc Polycomb 0.757
bowl brother of odd with entrails limited 0.753
fru fruitless 0.751
Su(var)3-7 Suppressor of variegation 3-7 0.750
Akt1 CG4006 gene product from transcript CG4006-RA 0.744
east enhanced adult sensory threshold 0.742
HGTX CG13475 gene product from transcript CG13475-RB 0.739
esg escargot 0.735
Rbf Retinoblastoma-family protein 0.730
phyl phyllopod 0.730
woc without children 0.727
dally division abnormally delayed 0.727
hb hunchback 0.725
sli slit 0.717
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tcf4 transcription factor 4 0.891
Junb jun B proto-oncogene 0.834
Jun Jun oncogene 0.812
Ier2 immediate early response 2 0.710
Btg2 BTG family, member 2 0.705
Tgfbr2 transforming growth factor, beta receptor II 0.619
Ppp2cb protein phosphatase 2, catalytic subunit, beta isoform 0.598
Tcfe2a transcription factor E2a 0.572
Zfp36 zinc finger protein 36 0.541
Met met proto-oncogene 0.460
Trim28 tripartite motif-containing 28 0.452
Nfib nuclear factor I/B 0.451
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.441
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.419
Dusp1 dual specificity phosphatase 1 0.417
RGD1565591 similar to Ski protein 0.414
Kcnt1 potassium channel, subfamily T, member 1 0.405
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.404
Siah1a seven in absentia 1A 0.394
Purb purine rich element binding protein B 0.388
Pgam1 phosphoglycerate mutase 1 (brain) 0.353
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.345
Dab2 disabled homolog 2 (Drosophila) 0.344
S100a8 S100 calcium binding protein A8 0.332
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.330
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.323
Smad7 SMAD family member 7 0.307
Vim vimentin 0.304
Neurog1 neurogenin 1 0.294
Hes1 hairy and enhancer of split 1 (Drosophila) 0.286
Ptma prothymosin alpha 0.285
Tcp11 t-complex protein 11 0.283
Gata6 GATA binding protein 6 0.282
Kdm6b lysine (K)-specific demethylase 6B 0.273
Anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.270
Hoxd3 homeo box D3 0.268
S100a9 S100 calcium binding protein A9 0.253
Cxxc5 CXXC finger 5 0.243
Rara retinoic acid receptor, alpha 0.241
Id1 inhibitor of DNA binding 1 0.238
Nfia nuclear factor I/A 0.233
Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.230
Mybl2 myeloblastosis oncogene-like 2 0.228
Klf2 Kruppel-like factor 2 (lung) 0.227
Ctcf CCCTC-binding factor (zinc finger protein) 0.226
Rest RE1-silencing transcription factor 0.225
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.225
Fos FBJ osteosarcoma oncogene 0.223
Pcna proliferating cell nuclear antigen 0.221
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.217
Ccnd1 cyclin D1 0.215
Wbp11 WW domain binding protein 11 0.215
Ubtf upstream binding transcription factor, RNA polymerase I 0.215
Ptprk protein tyrosine phosphatase, receptor type, K, extracellular region 0.214
Alx1 ALX homeobox 1 0.213
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.210
Anxa5 annexin A5 0.206
Dynll1 dynein light chain LC8-type 1 0.205
Eif4h eukaryotic translation initiation factor 4H 0.204
Drd3 dopamine receptor D3 0.204
Foxd1 forkhead box D1 0.203
Dbp D site of albumin promoter (albumin D-box) binding protein 0.197
Hmgb1 high mobility group box 1 0.196
Usf2 upstream transcription factor 2, c-fos interacting 0.191
Nfya nuclear transcription factor-Y alpha 0.190
Crybb3 crystallin, beta B3 0.190
Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.190
Grk1 G protein-coupled receptor kinase 1 0.185
Myh9 myosin, heavy chain 9, non-muscle 0.184
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.182
Pde4b phosphodiesterase 4B, cAMP specific 0.179
Foxi2 forkhead box I2 0.177
Sox7 SRY (sex determining region Y)-box 7 0.177
Abcb4 ATP-binding cassette, subfamily B (MDR/TAP), member 4 0.176
Hoxc4 homeo box C4 0.176
Kif1c kinesin family member 1C 0.174
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.171
Hist1h1d histone cluster 1, H1d 0.171
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.170
Ptpn1 protein tyrosine phosphatase, non-receptor type 1 0.170
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.170
Dlx5 distal-less homeobox 5 0.170
Ifitm3 interferon induced transmembrane protein 3 0.168
Socs3 suppressor of cytokine signaling 3 0.168
Ppara peroxisome proliferator activated receptor alpha 0.166
Prdm12 PR domain containing 12 0.165
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.163
Arf6 ADP-ribosylation factor 6 0.163
Dlg1 discs, large homolog 1 (Drosophila) 0.162
Irf1 interferon regulatory factor 1 0.162
Baiap2 BAI1-associated protein 2 0.161
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.160
Tmpo thymopoietin 0.159
Il1a interleukin 1 alpha 0.156
Eif1 eukaryotic translation initiation factor 1 0.154
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.153
Jak1 Janus kinase 1 0.153
Klf4 Kruppel-like factor 4 (gut) 0.152
Sf1 splicing factor 1 0.151
Raly RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) 0.151