The network for 'response to osmotic stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to osmotic stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
PBS2 Pbs2p 0.959
MYO5 Myo5p 0.948
SSK1 Ssk1p 0.856
FAR11 Far11p 0.762
CBK1 Cbk1p 0.691
BEM1 Bem1p 0.688
CKA2 Cka2p 0.681
SSK2 Ssk2p 0.613
PSR2 Psr2p 0.611
HOG1 Hog1p 0.600
BEM3 Bem3p 0.557
CLA4 Cla4p 0.538
STE50 Ste50p 0.500
MKK1 Mkk1p 0.485
AQY2 Aqy2p 0.480
NBP2 Nbp2p 0.480
STE11 Ste11p 0.445
FPS1 Fps1p 0.432
BOI2 Boi2p 0.427
SLT2 Slt2p 0.417
STE7 Ste7p 0.410
STE20 Ste20p 0.371
RHO1 Rho1p 0.350
CYC8 Cyc8p 0.312
CNB1 Cnb1p 0.299
BCK1 Bck1p 0.295
BBC1 Bbc1p 0.290
CMD1 Cmd1p 0.275
HOT1 Hot1p 0.273
OPY2 Opy2p 0.264
SCH9 Sch9p 0.259
SAC7 Sac7p 0.255
RSC9 Rsc9p 0.251
YKR015C hypothetical protein 0.247
RCK1 Rck1p 0.247
PTP2 Ptp2p 0.246
LAP4 Lap4p 0.245
SLA1 Sla1p 0.239
YPK2 Ypk2p 0.235
TOR2 Tor2p 0.234
CAB3 Cab3p 0.221
HAL5 Hal5p 0.220
PTK2 Ptk2p 0.213
CKA1 Cka1p 0.211
SSK22 Ssk22p 0.207
CRM1 Crm1p 0.206
VHS3 Vhs3p 0.206
HOP1 Hop1p 0.200
PKC1 Pkc1p 0.194
SIS2 Sis2p 0.187
UBP9 Ubp9p 0.182
DBF2 Dbf2p 0.178
FMP48 Fmp48p 0.178
MIG2 Mig2p 0.177
YNL134C hypothetical protein 0.174
TRK1 Trk1p 0.172
TPK1 Tpk1p 0.158
VHS2 Vhs2p 0.157
TPK2 Tpk2p 0.152
GPD1 Gpd1p 0.151
PRB1 Prb1p 0.149
CRZ1 Crz1p 0.143
GLN3 Gln3p 0.143
GAT2 Gat2p 0.143
GRE2 Gre2p 0.141
PDR12 Pdr12p 0.140
MET4 Met4p 0.140
HAL1 Hal1p 0.139
ROM2 Rom2p 0.138
HSE1 Hse1p 0.138
STE5 Ste5p 0.136
MID2 Mid2p 0.136
VAC7 Vac7p 0.129
HOF1 Hof1p 0.127
HKR1 Hkr1p 0.127
PGM3 Pgm3p 0.126
DSK2 Dsk2p 0.125
ENA5 Ena5p 0.124
PTC5 Ptc5p 0.123
HSL1 Hsl1p 0.119
UTP20 Utp20p 0.116
FPK1 Fpk1p 0.115
HXT3 Hxt3p 0.112
YPD1 Ypd1p 0.112
KAP95 Kap95p 0.110
PPZ1 Ppz1p 0.109
CAT8 Cat8p 0.109
SMP1 Smp1p 0.108
YPL150W hypothetical protein 0.105
CKB2 Ckb2p 0.105
ATG21 Atg21p 0.105
LRE1 Lre1p 0.105
SNF1 Snf1p 0.104
RTC3 Rtc3p 0.102
CCH1 Cch1p 0.102
BDH2 Bdh2p 0.102
KES1 Kes1p 0.101
PPH21 Pph21p 0.100
YNL144C hypothetical protein 0.097
CNA1 Cna1p 0.096
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
glr-5 Protein GLR-5 0.492
osm-5 Protein OSM-5 0.458
pdfr-1 Protein PDFR-1 0.337
osm-9 Protein OSM-9 0.264
che-11 Protein CHE-11 0.214
vab-8 Protein VAB-8 0.171
osm-3 Protein OSM-3 0.126
stn-1 Protein STN-1 0.125
dyb-1 Protein DYB-1 0.121
par-5 Protein PAR-5 0.105
gpb-1 Protein GPB-1 0.098
unc-18 Protein UNC-18 0.097
odr-3 Protein ODR-3 0.095
pkg-1 Protein PKG-1 0.091
best-3 Protein BEST-3 0.087
flt-1 Protein FLT-1 0.081
grk-2 Protein GRK-2 0.078
vha-5 Protein VHA-5 0.078
mrp-1 Protein MRP-1 0.073
unc-9 Protein UNC-9 0.072
kcnl-2 Protein KCNL-2 0.072
unc-45 Protein UNC-45 0.071
his-49 Protein HIS-49 0.070
akt-2 Protein AKT-2 0.067
F35H12.1 Protein F35H12.1 0.066
sec-15 Protein SEC-15 0.063
cat-1 Protein CAT-1 0.062
tax-6 Protein TAX-6 0.061
mec-10 Protein MEC-10 0.061
cam-1 Protein CAM-1 0.058
che-2 Protein CHE-2 0.057
mpk-1 Protein MPK-1 0.057
camt-1 Protein CAMT-1 0.055
egl-8 Protein EGL-8 0.055
mkk-4 Protein MKK-4 0.053
cysl-1 Protein CYSL-1 0.049
E04F6.6 Protein E04F6.6 0.048
eef-1A.1 Protein EEF-1A.1 0.048
daf-19 Protein DAF-19 0.047
sma-6 Protein SMA-6 0.047
B0416.5 Protein B0416.5 0.046
let-756 Protein LET-756 0.045
F21A10.2 Protein F21A10.2 0.045
nhr-120 Protein NHR-120 0.043
pssy-1 Protein PSSY-1 0.043
gei-4 Protein GEI-4 0.042
pef-1 Protein PEF-1 0.041
F38H4.3 Protein F38H4.3 0.041
eat-4 Protein EAT-4 0.041
K05C4.11 Protein K05C4.11 0.041
egal-1 Protein EGAL-1 0.041
unc-32 Protein UNC-32 0.041
daf-16 Protein DAF-16 0.040
sipa-1 Protein SIPA-1 0.040
lev-1 Protein LEV-1 0.039
hpk-1 Protein HPK-1 0.039
F52D10.6 Protein F52D10.6 0.039
eef-1A.2 Protein EEF-1A.2 0.038
lec-1 Protein LEC-1 0.037
tmc-2 Protein TMC-2 0.036
C49A9.5 Protein C49A9.5 0.036
F10E9.1 Protein F10E9.1 0.035
arrd-6 Protein ARRD-6 0.035
ugt-13 Protein UGT-13 0.035
acl-5 Protein ACL-5 0.035
lgc-55 Protein LGC-55 0.035
C03H5.6 Protein C03H5.6 0.034
fos-1 Protein FOS-1 0.034
egl-23 Protein EGL-23 0.033
C34F6.9 Protein C34F6.9 0.033
pat-12 Protein PAT-12 0.033
zfp-3 Protein ZFP-3 0.032
E04F6.4 Protein E04F6.4 0.032
F56F10.2 Protein F56F10.2 0.032
F41C3.11 Protein F41C3.11 0.032
rskn-2 Protein RSKN-2 0.031
che-13 Protein CHE-13 0.031
fbn-1 Protein FBN-1 0.031
D1009.3 Protein D1009.3 0.031
sax-3 Protein SAX-3 0.031
klp-3 Protein KLP-3 0.030
ceh-44 Protein CEH-44 0.030
ina-1 Protein INA-1 0.029
pmk-3 Protein PMK-3 0.029
acr-15 Protein ACR-15 0.029
mab-3 Protein MAB-3 0.029
lron-5 Protein LRON-5 0.029
F14F4.1 Protein F14F4.1 0.028
pab-2 Protein PAB-2 0.028
toe-4 Protein TOE-4 0.028
mig-2 Protein MIG-2 0.028
nhr-35 Protein NHR-35 0.028
spon-1 Protein SPON-1 0.028
ZC443.4 Protein ZC443.4 0.028
glr-1 Protein GLR-1 0.028
svh-2 Protein SVH-2 0.028
ced-3 Protein CED-3 0.027
nhr-208 Protein NHR-208 0.027
pkc-1 Protein PKC-1 0.027
unc-116 Protein UNC-116 0.027
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gria1a glutamate receptor, ionotropic, AMPA 1a 0.983
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.879
slc26a3 solute carrier family 26, member 3 0.829
ca2 carbonic anhydrase II 0.829
gria4a glutamate receptor, ionotropic, AMPA 4a 0.655
atp6v1al ATPase, H+ transporting, lysosomal V1 subunit A, like 0.650
gria1b glutamate receptor, ionotropic, AMPA 1b 0.533
gria3b glutamate receptor, ionotrophic, AMPA 3b 0.521
gria2b glutamate receptor, ionotropic, AMPA 2b 0.509
ca15a carbonic anhydrase XV a 0.491
gria4b glutamate receptor, ionotropic, AMPA 4b 0.455
ift88 intraflagellar transport 88 homolog 0.431
slc9a3.2 solute carrier family 9 (sodium/hydrogen exchanger), member 3.2 0.395
gria3a glutamate receptor, ionotropic, AMPA 3a 0.383
gria2a glutamate receptor, ionotropic, AMPA 2a 0.349
chrm2a cholinergic receptor, muscarinic 2a 0.259
slc26a4 solute carrier family 26, member 4 0.229
dab1b disabled homolog 1b (Drosophila) 0.227
celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 0.183
eno2 enolase 2 0.173
ntn2 netrin 2 0.107
slc12a10.2 solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2 0.107
slc2a13 solute carrier family 2 (facilitated glucose transporter), member 13 0.098
mgp matrix Gla protein 0.088
wnt10a wingless-type MMTV integration site family, member 10a 0.083
trpv1 transient receptor potential cation channel subfamily V member 1 0.080
LOC100005108 novel protein similar to solute carrier family 26, member 5 (slc26a5) 0.079
epas1b endothelial PAS domain protein 1b 0.078
pink1 PTEN induced putative kinase 1 0.077
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.066
rcor1 REST corepressor 1 0.063
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.062
LOC790901 glucose-dependent insulinotropic polypeptide 0.059
rhcgl1 Rhesus blood group, C glycoprotein, like 1 0.058
zgc:136878 zgc:136878 0.055
slc4a1b solute carrier family 4, anion exchanger, member 1b 0.054
LOC560602 novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6) 0.054
gc3 guanylyl cyclase 3 0.051
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.051
slc2a9l2 solute carrier family 2 (facilitated glucose transporter), member 9-like 2 0.049
zgc:171872 zgc:171872 0.048
rhag Rhesus blood group-associated glycoprotein 0.046
si:ch211-284e13.2 si:ch211-284e13.2 0.046
pou3f2 POU class 3 homeobox 2 0.043
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.043
reln reelin 0.042
slc2a12 solute carrier family 2 (facilitated glucose transporter), member 12 0.041
ccng1 cyclin G1 0.040
gper G protein-coupled estrogen receptor 1 0.037
cyp24a1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.036
pthlh parathyroid hormone-like hormone 0.036
kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.036
ift57 intraflagellar transport protein 57 0.033
ppp3r1a protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, a 0.033
mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.032
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.031
csad cysteine sulfinic acid decarboxylase 0.030
zgc:101724 zgc:101724 0.030
si:ch73-9j13.1 si:ch73-9j13.1 0.029
nxph1 neurexophilin 1 0.029
camsap1l1 calmodulin regulated spectrin-associated protein 1-like 1 0.028
mef2d myocyte enhancer factor 2d 0.028
ef1a elongation factor 1-alpha 0.028
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.028
nr0b1 nuclear receptor subfamily 0, group B, member 1 0.027
mapk1 mitogen-activated protein kinase 1 0.027
wu:fb80a07 wu:fb80a07 0.027
neurog3 neurogenin 3 0.026
vasp vasodilator-stimulated phosphoprotein 0.026
stx1b syntaxin 1B 0.026
ptn pleiotrophin 0.025
npdc1 neural proliferation, differentiation and control, 1 0.025
casrl calcium-sensing receptor, like 0.025
prox1 prospero-related homeobox gene 1 0.024
slc17a6a solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6a 0.024
uxs1 UDP-glucuronic acid decarboxylase 1 0.023
mkrn2 makorin, ring finger protein, 2 0.023
zgc:56010 zgc:56010 0.023
usp4 ubiquitin specific protease 4 (proto-oncogene) 0.022
otpa orthopedia homolog a 0.022
eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) 0.021
zgc:101523 zgc:101523 0.021
zgc:56304 zgc:56304 0.021
hk1 hexokinase 1 0.021
ptpn1 protein tyrosine phosphatase, non-receptor type 1 0.021
lhx2a LIM homeobox 2a 0.021
rhcgb Rhesus blood group, C glycoprotein b 0.021
rgs4 regulator of G-protein signalling 4 0.020
rtn4b reticulon 4b 0.019
mapk7 mitogen-activated protein kinase 7 0.019
ghrl ghrelin/obestatin preprohormone 0.019
a2ml alpha-2-macroglobulin-like 0.019
dctn1a dynactin 1a 0.019
cx35 connexin 35 0.019
cdk10 cyclin-dependent kinase 10 0.019
bag6 BCL2-associated athanogene 6 0.018
ilk integrin linked kinase 0.018
panx1 pannexin 1 0.018
sema6dl sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like 0.018
ddc dopa decarboxylase 0.018
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
par-1 CG8201 gene product from transcript CG8201-RA 0.581
Pkn Protein kinase related to protein kinase N 0.542
Ca-beta Ca2+-channel-protein-beta-subunit 0.480
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.474
rl rolled 0.362
Rala Ras-related protein 0.340
Nmdar2 NMDA receptor 2 0.290
Mekk1 CG7717 gene product from transcript CG7717-RB 0.253
drk downstream of receptor kinase 0.206
ppk11 pickpocket 11 0.190
foxo forkhead box, sub-group O 0.172
Rab7 Rab-protein 7 0.165
Atf-2 Activating transcription factor-2 0.163
cno canoe 0.162
CG13568 CG13568 gene product from transcript CG13568-RG 0.157
mth methuselah 0.146
Ric Ras which interacts with Calmodulin 0.124
CG32792 CG32792 gene product from transcript CG32792-RF 0.115
CG12370 CG12370 gene product from transcript CG12370-RB 0.107
Rho1 CG8416 gene product from transcript CG8416-RB 0.104
Tl Toll 0.099
Irk3 Inwardly rectifying potassium channel 3 0.097
Mpk2 CG5475 gene product from transcript CG5475-RB 0.096
Gr32a Gustatory receptor 32a 0.090
Gr64a Gustatory receptor 64a 0.089
CG33289 CG33289 gene product from transcript CG33289-RA 0.085
Acsl Acyl-CoA synthetase long-chain 0.079
Dcr-2 Dicer-2 0.078
cert ceramide transfer protein 0.077
Gr33a Gustatory receptor 33a 0.077
Nach CG8178 gene product from transcript CG8178-RA 0.076
cta concertina 0.074
Tak1 TGF-beta activated kinase 1 0.071
Wnk CG7177 gene product from transcript CG7177-RA 0.069
5-HT7 Serotonin receptor 7 0.069
tacc transforming acidic coiled-coil protein 0.066
CG5001 CG5001 gene product from transcript CG5001-RA 0.063
Gyc88E Guanylyl cyclase at 88E 0.062
CG6776 CG6776 gene product from transcript CG6776-RA 0.061
CheB42a Chemosensory protein B 42a 0.058
Ubqn Ubiquilin 0.058
Pink1 PTEN-induced putative kinase 1 0.057
Tbh Tyramine beta hydroxylase 0.056
Tpi Triose phosphate isomerase 0.053
Gr64c Gustatory receptor 64c 0.052
Gr43a Gustatory receptor 43a 0.049
Gyc76C Guanylyl cyclase at 76C 0.045
Eip63F-1 Ecdysone-induced protein 63F 1 0.044
Gr64e Gustatory receptor 64e 0.040
zetaTry zetaTrypsin 0.039
NAAT1 Nutrient Amino Acid Transporter 1 0.038
CG12187 CG12187 gene product from transcript CG12187-RA 0.035
fusl fuseless 0.034
Stim Stromal interaction molecule 0.034
Gr59c Gustatory receptor 59c 0.034
stnB stoned B 0.033
CG4328 CG4328 gene product from transcript CG4328-RB 0.032
dib disembodied 0.032
Gr64f Gustatory receptor 64f 0.030
eag ether a go-go 0.030
CG5794 CG5794 gene product from transcript CG5794-RB 0.029
Hnf4 Hepatocyte nuclear factor 4 0.029
shakB shaking B 0.029
CG34388 CG34388 gene product from transcript CG34388-RC 0.029
krz kurtz 0.027
ppk25 pickpocket 25 0.027
lush CG8807 gene product from transcript CG8807-RA 0.026
CG12020 CG12020 gene product from transcript CG12020-RA 0.025
Tsp96F Tetraspanin 96F 0.025
ine inebriated 0.025
cpo couch potato 0.024
S6k RPS6-p70-protein kinase 0.024
KCNQ KCNQ potassium channel 0.024
spo spook 0.024
CG10431 CG10431 gene product from transcript CG10431-RA 0.023
kst karst 0.023
Fmr1 CG6203 gene product from transcript CG6203-RC 0.023
Rel Relish 0.022
CG14369 CG14369 gene product from transcript CG14369-RA 0.021
Esyt2 CG6643 gene product from transcript CG6643-RA 0.021
GluRIIE Glutamate receptor IIE 0.021
CG13792 CG13792 gene product from transcript CG13792-RA 0.021
fd19B forkhead domain 19B 0.021
CG14234 CG14234 gene product from transcript CG14234-RA 0.020
CG2316 CG2316 gene product from transcript CG2316-RD 0.020
VhaPPA1-1 CG7007 gene product from transcript CG7007-RA 0.019
Pde8 Phosphodiesterase 8 0.019
Lsd-2 Lipid storage droplet-2 0.019
CG31191 CG31191 gene product from transcript CG31191-RA 0.018
Hph HIF prolyl hydroxylase 0.018
ClC-b Chloride channel-b 0.018
Tehao CG7121 gene product from transcript CG7121-RA 0.018
lqf liquid facets 0.018
Msr-110 CG10596 gene product from transcript CG10596-RB 0.018
CG13506 CG13506 gene product from transcript CG13506-RA 0.017
Gr64b Gustatory receptor 64b 0.017
MTF-1 Metal response element-binding Transcription Factor-1 0.017
CaMKII Calcium/calmodulin-dependent protein kinase II 0.016
nwk nervous wreck 0.016
lola longitudinals lacking 0.016
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
MAPK14 mitogen-activated protein kinase 14 0.989
MAP2K4 mitogen-activated protein kinase kinase 4 0.792
JUN jun proto-oncogene 0.606
DUSP1 dual specificity phosphatase 1 0.596
ATF2 activating transcription factor 2 0.492
MAPK1 mitogen-activated protein kinase 1 0.454
NCOA3 nuclear receptor coactivator 3 0.331
FOS FBJ murine osteosarcoma viral oncogene homolog 0.225
DNM2 dynamin 2 0.170
MAPK3 mitogen-activated protein kinase 3 0.156
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.150
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.147
SCNN1B sodium channel, nonvoltage-gated 1, beta 0.132
CAB39 calcium binding protein 39 0.117
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.108
HDAC4 histone deacetylase 4 0.103
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.097
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.064
ZFP36L1 zinc finger protein 36, C3H type-like 1 0.062
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.056
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.053
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.052
SOCS3 suppressor of cytokine signaling 3 0.052
LRRK2 leucine-rich repeat kinase 2 0.050
RB1 retinoblastoma 1 0.049
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.048
MAP2K6 mitogen-activated protein kinase kinase 6 0.047
ATF3 activating transcription factor 3 0.046
ARRB1 arrestin, beta 1 0.041
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.040
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.038
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.037
JUNB jun B proto-oncogene 0.035
MED31 mediator complex subunit 31 0.034
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.032
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.028
PAX8 paired box 8 0.026
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.026
CCR5 chemokine (C-C motif) receptor 5 0.026
SH3RF1 SH3 domain containing ring finger 1 0.025
HTT huntingtin 0.024
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.023
MAPK11 mitogen-activated protein kinase 11 0.023
FASLG Fas ligand (TNF superfamily, member 6) 0.023
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.023
MAPK8 mitogen-activated protein kinase 8 0.023
CUL2 cullin 2 0.022
IRF2 interferon regulatory factor 2 0.022
MAPK12 mitogen-activated protein kinase 12 0.022
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.022
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.022
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.021
IER2 immediate early response 2 0.021
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.021
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.021
EPOR erythropoietin receptor 0.020
MAP2K3 mitogen-activated protein kinase kinase 3 0.020
DUSP7 dual specificity phosphatase 7 0.019
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.019
CRH corticotropin releasing hormone 0.019
ADAMTSL4 ADAMTS-like 4 0.019
PKN1 protein kinase N1 0.019
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.019
JUND jun D proto-oncogene 0.018
EGR1 early growth response 1 0.018
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.018
BCL6 B-cell CLL/lymphoma 6 0.018
GADD45B growth arrest and DNA-damage-inducible, beta 0.017
ARRB2 arrestin, beta 2 0.017
BAK1 BCL2-antagonist/killer 1 0.017
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.017
CTTN cortactin 0.017
MEF2A myocyte enhancer factor 2A 0.016
EIF4A3 eukaryotic translation initiation factor 4A3 0.016
DUSP9 dual specificity phosphatase 9 0.016
CREB1 cAMP responsive element binding protein 1 0.016
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.016
ZNF282 zinc finger protein 282 0.016
CPNE6 copine VI (neuronal) 0.016
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.015
FKBP8 FK506 binding protein 8, 38kDa 0.015
RNF144B ring finger protein 144B 0.015
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.015
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.015
MAPK9 mitogen-activated protein kinase 9 0.015
IQGAP1 IQ motif containing GTPase activating protein 1 0.015
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.014
ATXN3 ataxin 3 0.014
VIM vimentin 0.014
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.014
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.013
MEF2C myocyte enhancer factor 2C 0.013
HSF1 heat shock transcription factor 1 0.013
HDAC9 histone deacetylase 9 0.012
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.012
RNF11 ring finger protein 11 0.012
CUL1 cullin 1 0.012
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.012
FLNB filamin B, beta 0.012
USP10 ubiquitin specific peptidase 10 0.012
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Mapk14 mitogen-activated protein kinase 14 1.000
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.999
Pten phosphatase and tensin homolog 0.997
Rac1 RAS-related C3 botulinum substrate 1 0.997
Ren1 renin 1 structural 0.996
Slc12a1 solute carrier family 12, member 1 0.993
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 0.977
Tgfb1 transforming growth factor, beta 1 0.968
Umod uromodulin 0.967
Wnk4 WNK lysine deficient protein kinase 4 0.870
Atf2 activating transcription factor 2 0.862
Mapk11 mitogen-activated protein kinase 11 0.846
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.842
Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 0.754
Alb albumin 0.751
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.662
Capn1 calpain 1 0.657
Nfatc3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.649
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.631
Trp53 transformation related protein 53 0.629
Akt1 thymoma viral proto-oncogene 1 0.618
Cyld cylindromatosis (turban tumor syndrome) 0.572
Rxra retinoid X receptor alpha 0.552
Mapkapk2 MAP kinase-activated protein kinase 2 0.520
Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like 0.513
Nsf N-ethylmaleimide sensitive fusion protein 0.507
Hdac4 histone deacetylase 4 0.506
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.468
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.468
Dysf dysferlin 0.449
Ryr2 ryanodine receptor 2, cardiac 0.434
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.426
Bsnd Bartter syndrome, infantile, with sensorineural deafness (Barttin) 0.413
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.404
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.391
Bak1 BCL2-antagonist/killer 1 0.388
Hdac7 histone deacetylase 7 0.382
S100a10 S100 calcium binding protein A10 (calpactin) 0.380
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.361
Flii flightless I homolog (Drosophila) 0.360
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.352
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) 0.348
Ret ret proto-oncogene 0.331
Axin1 axin 1 0.327
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.290
Smurf2 SMAD specific E3 ubiquitin protein ligase 2 0.286
Agtr1a angiotensin II receptor, type 1a 0.280
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.277
Shh sonic hedgehog 0.268
Rara retinoic acid receptor, alpha 0.264
Nr3c2 nuclear receptor subfamily 3, group C, member 2 0.261
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.247
Myo1c myosin IC 0.244
Mapk8 mitogen-activated protein kinase 8 0.241
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.232
Epn1 epsin 1 0.226
Dlg1 discs, large homolog 1 (Drosophila) 0.222
Uox urate oxidase 0.220
Mapk3 mitogen-activated protein kinase 3 0.211
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.209
Stat6 signal transducer and activator of transcription 6 0.209
Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.208
Bax BCL2-associated X protein 0.193
Map2k3 mitogen-activated protein kinase kinase 3 0.190
Aprt adenine phosphoribosyl transferase 0.189
Ina internexin neuronal intermediate filament protein, alpha 0.180
Prkce protein kinase C, epsilon 0.180
Dmd dystrophin, muscular dystrophy 0.176
Slc12a2 solute carrier family 12, member 2 0.175
Fbn1 fibrillin 1 0.171
Map2k1 mitogen-activated protein kinase kinase 1 0.171
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.162
Cacna2d2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.157
Oxr1 oxidation resistance 1 0.146
Stk39 serine/threonine kinase 39, STE20/SPS1 homolog (yeast) 0.144
Mef2c myocyte enhancer factor 2C 0.143
Emx1 empty spiracles homolog 1 (Drosophila) 0.143
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.140
Csk c-src tyrosine kinase 0.134
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.134
Arhgap1 Rho GTPase activating protein 1 0.133
Mapk1 mitogen-activated protein kinase 1 0.132
Nos1 nitric oxide synthase 1, neuronal 0.131
Kl klotho 0.130
Lepr leptin receptor 0.127
Mb myoglobin 0.127
Hdac5 histone deacetylase 5 0.124
Agtr2 angiotensin II receptor, type 2 0.123
Necap2 NECAP endocytosis associated 2 0.121
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.114
Anxa5 annexin A5 0.112
Scnn1g sodium channel, nonvoltage-gated 1 gamma 0.112
Map2k4 mitogen-activated protein kinase kinase 4 0.110
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.109
Slc12a6 solute carrier family 12, member 6 0.109
Scnn1b sodium channel, nonvoltage-gated 1 beta 0.107
Rhog ras homolog gene family, member G 0.107
Epn3 epsin 3 0.105
Nfatc4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.104
Bcl2 B-cell leukemia/lymphoma 2 0.101
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Ugt8 UDP glycosyltransferase 8 0.172
Stra6 stimulated by retinoic acid gene 6 0.129
Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.103
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.094
Mrgprf MAS-related GPR, member F 0.093
Slc22a25 solute carrier family 22, member 25 0.091
Rdh2 retinol dehydrogenase 2 0.085
Stip1 stress-induced phosphoprotein 1 0.083
Chrm1 cholinergic receptor, muscarinic 1 0.062
Hsph1 heat shock 105/110 protein 1 0.062
Olr226 olfactory receptor 226 0.052
Ccl3 chemokine (C-C motif) ligand 3 0.048
Vip vasoactive intestinal peptide 0.048
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.046
Prol1 proline rich, lacrimal 1 0.043
Dctn4 dynactin 4 0.041
Dnase1 deoxyribonuclease I 0.041
Padi2 peptidyl arginine deiminase, type II 0.040
Adam2 ADAM metallopeptidase domain 2 0.038
Igf2 insulin-like growth factor 2 0.038
Eef2 eukaryotic translation elongation factor 2 0.038
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.037
Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 0.037
Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 0.037
Gpr37l1 G protein-coupled receptor 37-like 1 0.037
Hr hairless 0.036
Mapk1 mitogen activated protein kinase 1 0.036
Padi3 peptidyl arginine deiminase, type III 0.035
Prkacb protein kinase, cAMP dependent, catalytic, beta 0.033
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.033
Cela1 chymotrypsin-like elastase family, member 1 0.032
Reg3b regenerating islet-derived 3 beta 0.032
Grk1 G protein-coupled receptor kinase 1 0.032
Aqp7 aquaporin 7 0.032
Akp3 alkaline phosphatase 3, intestine, not Mn requiring 0.030
Plscr3 phospholipid scramblase 3 0.030
Npffr2 neuropeptide FF receptor 2 0.030
Fmo2 flavin containing monooxygenase 2 0.029
Errfi1 ERBB receptor feedback inhibitor 1 0.029
Hspa8 heat shock protein 8 0.029
Notch3 Notch homolog 3 (Drosophila) 0.029
Obp2b odorant binding protein 2B 0.028
Nsf N-ethylmaleimide-sensitive factor 0.028
Kcnt1 potassium channel, subfamily T, member 1 0.028
Heatr5a HEAT repeat containing 5A 0.028
L1cam L1 cell adhesion molecule 0.028
Pnoc prepronociceptin 0.028
Zg16 zymogen granule protein 16 0.027
Mag myelin-associated glycoprotein 0.027
Prr15 proline rich 15 0.027
Nlgn3 neuroligin 3 0.027
Oprm1 opioid receptor, mu 1 0.026
Capn8 calpain 8 0.026
Txnip thioredoxin interacting protein 0.026
Pla2g5 phospholipase A2, group V 0.025
Tmem79 transmembrane protein 79 0.025
Add2 adducin 2 (beta) 0.025
Grm7 glutamate receptor, metabotropic 7 0.025
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.025
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.025
Scnn1b sodium channel, nonvoltage-gated 1, beta 0.025
Il2rb interleukin 2 receptor, beta 0.025
Tep1 telomerase associated protein 1 0.025
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.025
Nrcam neuronal cell adhesion molecule 0.024
Khk ketohexokinase 0.024
Git1 G protein-coupled receptor kinase interacting ArfGAP 1 0.024
Nfasc neurofascin 0.024
Fam38b family with sequence similarity 38, member B 0.024
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.024
Gip gastric inhibitory polypeptide 0.024
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.024
Cx3cl1 chemokine (C-X3-C motif) ligand 1 0.024
Itga7 integrin, alpha 7 0.023
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.023
Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.023
Klrb1a killer cell lectin-like receptor subfamily B, member 1A 0.023
Mmp3 matrix metallopeptidase 3 0.023
Plau plasminogen activator, urokinase 0.023
Dhdpsl dihydrodipicolinate synthase-like, mitochondrial 0.023
Fmo3 flavin containing monooxygenase 3 0.023
Ms4a8a membrane-spanning 4-domains, subfamily A, member 8A 0.023
Lpar2 lysophosphatidic acid receptor 2 0.023
Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.023
Glul glutamate-ammonia ligase (glutamine synthetase) 0.022
Hrh2 histamine receptor H 2 0.022
Ucn urocortin 0.022
Gpr116 G protein-coupled receptor 116 0.022
Th tyrosine hydroxylase 0.022
Gstm2 glutathione S-transferase mu 2 0.022
Musk muscle, skeletal, receptor tyrosine kinase 0.022
Ptpn5 protein tyrosine phosphatase, non-receptor type 5 0.022
Igsf7 immunoglobulin superfamily, member 7 0.022
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.022
Lipe lipase, hormone sensitive 0.022
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.022
Dapk3 death-associated protein kinase 3 0.022
Gzmk granzyme K 0.022
Rnf4 ring finger protein 4 0.021
Lect1 leukocyte cell derived chemotaxin 1 0.021