The network for 'iron sulfur cluster assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

iron sulfur cluster assembly

The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.

Name Description Probability Func Analog Organism
NFS1 Nfs1p 0.934
YHR122W hypothetical protein 0.933
ISU1 Isu1p 0.886
REG1 Reg1p 0.696
NFU1 Nfu1p 0.594
ISA1 Isa1p 0.535
YPL260W hypothetical protein 0.379
CFD1 Cfd1p 0.374
CIA1 Cia1p 0.300
TIM44 Tim44p 0.239
UTR1 Utr1p 0.219
NUR1 Nur1p 0.201
NTG1 Ntg1p 0.157
MDJ1 Mdj1p 0.154
PTK2 Ptk2p 0.147
ISD11 Isd11p 0.140
NBP35 Nbp35p 0.134
DRE2 Dre2p 0.131
SAK1 Sak1p 0.130
RAD59 Rad59p 0.110
SSQ1 Ssq1p 0.107
NAR1 Nar1p 0.101
YNL295W hypothetical protein 0.084
YFH1 Yfh1p 0.076
PET112 Pet112p 0.070
YPL014W hypothetical protein 0.066
ATR1 Atr1p 0.062
LST8 Lst8p 0.060
ADR1 Adr1p 0.058
PBP4 Pbp4p 0.058
FPK1 Fpk1p 0.058
NTA1 Nta1p 0.052
MBF1 Mbf1p 0.052
PRS2 Prs2p 0.051
TGL4 Tgl4p 0.047
MNR2 Mnr2p 0.044
ALT2 Alt2p 0.043
YNL260C hypothetical protein 0.043
SFA1 Sfa1p 0.040
BMH2 Bmh2p 0.039
VHR1 Vhr1p 0.038
ARG8 Arg8p 0.038
SRD1 Srd1p 0.037
HAL5 Hal5p 0.037
FRA1 Fra1p 0.036
MSY1 Msy1p 0.034
ACP1 Acp1p 0.034
YGR016W hypothetical protein 0.033
QCR8 Qcr8p 0.033
YNL234W hypothetical protein 0.032
GRX5 Grx5p 0.032
RIB7 Rib7p 0.032
YKL023W hypothetical protein 0.031
YDL180W hypothetical protein 0.031
HAA1 Haa1p 0.030
PAM1 Pam1p 0.030
AIM33 Aim33p 0.030
RIB1 Rib1p 0.029
CAK1 Cak1p 0.029
IES6 Ies6p 0.029
MDS3 Mds3p 0.029
YLR162W hypothetical protein 0.029
KTI12 Kti12p 0.028
YKR075C hypothetical protein 0.028
ISU2 Isu2p 0.028
TOM7 Tom7p 0.027
SAS5 Sas5p 0.027
MET8 Met8p 0.027
YOL038C-A hypothetical protein 0.027
MEF2 Mef2p 0.027
DOG1 Dog1p 0.026
DNA2 Dna2p 0.026
PUT2 Put2p 0.026
LEU2 Leu2p 0.026
YLR264C-A hypothetical protein 0.026
YLR108C hypothetical protein 0.025
SNF1 Snf1p 0.025
HXT3 Hxt3p 0.025
LEU5 Leu5p 0.025
NSG2 Nsg2p 0.025
YPL216W hypothetical protein 0.024
YIR014W hypothetical protein 0.024
MF(ALPHA)2 Mf(alpha)2p 0.024
HRK1 Hrk1p 0.024
YMR102C hypothetical protein 0.023
UBA3 Uba3p 0.023
TIM23 Tim23p 0.023
CTM1 Ctm1p 0.022
JAC1 Jac1p 0.022
LYS20 Lys20p 0.022
URA6 Ura6p 0.022
FMP48 Fmp48p 0.021
SSK1 Ssk1p 0.021
BSC2 Bsc2p 0.021
MER1 Mer1p 0.021
CUP1-1 Cup1-1p 0.021
URA3 Ura3p 0.020
YLR042C hypothetical protein 0.020
CAB2 Cab2p 0.020
SNG1 Sng1p 0.020
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
copz1 coatomer protein complex, subunit zeta 1 0.017
zgc:163093 zgc:163093 0.012
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FAM96A family with sequence similarity 96, member A 0.394
FAM96B family with sequence similarity 96, member B 0.275
HEATR2 HEAT repeat containing 2 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Sdhaf2 succinate dehydrogenase complex assembly factor 2 0.750
Mrps23 mitochondrial ribosomal protein S23 0.508
Hmbs hydroxymethylbilane synthase 0.454
Nubp1 nucleotide binding protein 1 0.443
Dus1l dihydrouridine synthase 1-like (S. cerevisiae) 0.420
Nubp2 nucleotide binding protein 2 0.398
Ptcd2 pentatricopeptide repeat domain 2 0.383
Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 0.378
Mrpl16 mitochondrial ribosomal protein L16 0.356
Ddx41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 0.344
Mrps18b mitochondrial ribosomal protein S18B 0.333
Parl presenilin associated, rhomboid-like 0.327
Mrps7 mitchondrial ribosomal protein S7 0.321
Psmg1 proteasome (prosome, macropain) assembly chaperone 1 0.301
Slc25a11 solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 0.300
Exosc5 exosome component 5 0.282
Nudt1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.255
Mrpl37 mitochondrial ribosomal protein L37 0.252
Ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.240
2610027L16Rik RIKEN cDNA 2610027L16 gene 0.240
Vps25 vacuolar protein sorting 25 (yeast) 0.215
Grpel1 GrpE-like 1, mitochondrial 0.206
Wdr46 WD repeat domain 46 0.195
Mrpl40 mitochondrial ribosomal protein L40 0.186
Ciao1 cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae) 0.186
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.183
Pdhb pyruvate dehydrogenase (lipoamide) beta 0.172
Uqcc ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast) 0.159
Immp1l IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.159
Polr3c polymerase (RNA) III (DNA directed) polypeptide C 0.150
Mrpl2 mitochondrial ribosomal protein L2 0.148
Lsm4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.146
Imp4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) 0.145
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.143
Ngrn neugrin, neurite outgrowth associated 0.135
Gins4 GINS complex subunit 4 (Sld5 homolog) 0.134
Mtx1 metaxin 1 0.127
Prdx3 peroxiredoxin 3 0.122
Exosc4 exosome component 4 0.119
Mrpl9 mitochondrial ribosomal protein L9 0.109
Coq9 coenzyme Q9 homolog (yeast) 0.107
Acyp1 acylphosphatase 1, erythrocyte (common) type 0.106
Ndufaf1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 0.104
Mrpl49 mitochondrial ribosomal protein L49 0.101
Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.096
Hagh hydroxyacyl glutathione hydrolase 0.092
2310061C15Rik RIKEN cDNA 2310061C15 gene 0.090
Jagn1 jagunal homolog 1 (Drosophila) 0.088
Gtf2h4 general transcription factor II H, polypeptide 4 0.086
Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 0.085
Coq6 coenzyme Q6 homolog (yeast) 0.078
Ndufa9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 0.078
1700040I03Rik RIKEN cDNA 1700040I03 gene 0.077
Eif2b1 eukaryotic translation initiation factor 2B, subunit 1 (alpha) 0.076
Ccdc142 coiled-coil domain containing 142 0.074
Foxred1 FAD-dependent oxidoreductase domain containing 1 0.073
Banf1 barrier to autointegration factor 1 0.072
Brp44 brain protein 44 0.069
2310011J03Rik RIKEN cDNA 2310011J03 gene 0.068
Zswim7 zinc finger, SWIM-type containing 7 0.067
Thoc6 THO complex 6 homolog (Drosophila) 0.066
Ccdc56 coiled-coil domain containing 56 0.065
2410001C21Rik RIKEN cDNA 2410001C21 gene 0.065
Nit2 nitrilase family, member 2 0.062
Triap1 TP53 regulated inhibitor of apoptosis 1 0.061
Dctpp1 dCTP pyrophosphatase 1 0.060
Sssca1 Sjogren's syndrome/scleroderma autoantigen 1 homolog (human) 0.059
Mrps28 mitochondrial ribosomal protein S28 0.059
Apip APAF1 interacting protein 0.059
Wdr83 WD repeat domain containing 83 0.057
Ghitm growth hormone inducible transmembrane protein 0.055
Rnaseh2a ribonuclease H2, large subunit 0.055
Tmem208 transmembrane protein 208 0.054
Ssna1 Sjogren's syndrome nuclear autoantigen 1 0.054
Ccndbp1 cyclin D-type binding-protein 1 0.053
Ppp4c protein phosphatase 4, catalytic subunit 0.053
Sirt3 sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae) 0.052
Sdhd succinate dehydrogenase complex, subunit D, integral membrane protein 0.052
Ubac1 ubiquitin associated domain containing 1 0.051
Aurkaip1 aurora kinase A interacting protein 1 0.050
Chmp6 chromatin modifying protein 6 0.049
2410091C18Rik RIKEN cDNA 2410091C18 gene 0.049
Smn1 survival motor neuron 1 0.049
Slc30a6 solute carrier family 30 (zinc transporter), member 6 0.049
Eif6 eukaryotic translation initiation factor 6 0.045
Phb prohibitin 0.044
AI462493 expressed sequence AI462493 0.044
Suclg1 succinate-CoA ligase, GDP-forming, alpha subunit 0.044
Stk16 serine/threonine kinase 16 0.043
Etfdh electron transferring flavoprotein, dehydrogenase 0.041
Sharpin SHANK-associated RH domain interacting protein 0.040
5430437P03Rik RIKEN cDNA 5430437P03 gene 0.040
Lrrc59 leucine rich repeat containing 59 0.039
1810009A15Rik RIKEN cDNA 1810009A15 gene 0.038
Mlx MAX-like protein X 0.038
Sec13 SEC13 homolog (S. cerevisiae) 0.037
Mrps27 mitochondrial ribosomal protein S27 0.037
Urod uroporphyrinogen decarboxylase 0.036
Eefsec eukaryotic elongation factor, selenocysteine-tRNA-specific 0.036
Scnm1 sodium channel modifier 1 0.036
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Rattus norvegicus
Name Description Probability Func Analog Organism