The network for 'regulation of cell cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GLC7 Glc7p 0.990
CLA4 Cla4p 0.960
CDC28 Cdc28p 0.942
ZDS2 Zds2p 0.826
RAD53 Rad53p 0.777
PPH22 Pph22p 0.748
RPD3 Rpd3p 0.730
KIN1 Kin1p 0.729
CDC20 Cdc20p 0.726
PPH3 Pph3p 0.717
BUB3 Bub3p 0.709
RAD54 Rad54p 0.686
CLB3 Clb3p 0.669
SIC1 Sic1p 0.626
BCK1 Bck1p 0.622
DPB2 Dpb2p 0.618
PBS2 Pbs2p 0.618
CLB6 Clb6p 0.618
HSL1 Hsl1p 0.617
PDS1 Pds1p 0.585
SCH9 Sch9p 0.543
HOG1 Hog1p 0.513
KAP95 Kap95p 0.511
SLK19 Slk19p 0.500
GIC1 Gic1p 0.497
SWI5 Swi5p 0.495
SPT5 Spt5p 0.487
HHT1 Hht1p 0.465
KEL1 Kel1p 0.457
SNT1 Snt1p 0.453
CMD1 Cmd1p 0.451
SSK2 Ssk2p 0.446
PHO81 Pho81p 0.445
BEM1 Bem1p 0.441
MPS1 Mps1p 0.440
YDJ1 Ydj1p 0.434
AVO1 Avo1p 0.429
GBP2 Gbp2p 0.427
CSM1 Csm1p 0.426
CLN1 Cln1p 0.426
PSK1 Psk1p 0.424
BUB1 Bub1p 0.417
EAF1 Eaf1p 0.417
HHO1 Hho1p 0.416
PPZ2 Ppz2p 0.412
MUS81 Mus81p 0.407
SKP1 Skp1p 0.404
PRP8 Prp8p 0.394
MOB1 Mob1p 0.392
STE20 Ste20p 0.387
MET4 Met4p 0.384
PPH21 Pph21p 0.384
PSR2 Psr2p 0.381
RPT3 Rpt3p 0.380
CDC16 Cdc16p 0.380
CTF4 Ctf4p 0.377
RTT107 Rtt107p 0.375
GIC2 Gic2p 0.372
MCM4 Mcm4p 0.366
BBC1 Bbc1p 0.364
POL30 Pol30p 0.356
MND2 Mnd2p 0.353
SHS1 Shs1p 0.334
ROM2 Rom2p 0.331
MAD2 Mad2p 0.324
SPT16 Spt16p 0.317
ULP2 Ulp2p 0.316
CDC15 Cdc15p 0.313
VHS1 Vhs1p 0.312
KIC1 Kic1p 0.311
CDC10 Cdc10p 0.307
KSP1 Ksp1p 0.307
RPN3 Rpn3p 0.307
APC11 Apc11p 0.304
CSE4 Cse4p 0.301
YBP2 Ybp2p 0.301
TPS1 Tps1p 0.299
STE11 Ste11p 0.298
RIO2 Rio2p 0.297
SET3 Set3p 0.297
DCC1 Dcc1p 0.296
BFA1 Bfa1p 0.295
PLC1 Plc1p 0.293
CLB5 Clb5p 0.292
KSS1 Kss1p 0.292
CDC43 Cdc43p 0.290
MCM6 Mcm6p 0.289
CSM3 Csm3p 0.288
MCM10 Mcm10p 0.288
FUS3 Fus3p 0.287
MTH1 Mth1p 0.286
CKA2 Cka2p 0.283
HFI1 Hfi1p 0.282
CDC23 Cdc23p 0.277
NUP170 Nup170p 0.276
GLN3 Gln3p 0.273
CTR9 Ctr9p 0.271
ASK10 Ask10p 0.270
FPK1 Fpk1p 0.270
LSM5 Lsm5p 0.270
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.947
mat-3 Protein MAT-3 0.914
lag-1 Protein LAG-1 0.650
lin-12 Protein LIN-12 0.632
hgrs-1 Protein HGRS-1 0.625
uaf-1 Protein UAF-1 0.570
CELE_C24H12.5 Protein C24H12.5 0.522
skp-1 Protein SKP-1 0.509
lmn-1 Protein LMN-1 0.507
atn-1 Protein ATN-1 0.488
thoc-2 Protein THOC-2 0.476
C50F2.3 Protein C50F2.3 0.475
cks-1 Protein CKS-1 0.470
gpr-2 Protein GPR-2 0.467
cdc-6 Protein CDC-6 0.461
nhr-67 Protein NHR-67 0.448
cyk-4 Protein CYK-4 0.424
mex-5 Protein MEX-5 0.421
his-32 Protein HIS-32 0.420
gpb-2 Protein GPB-2 0.412
asd-1 Protein ASD-1 0.400
sas-5 Protein SAS-5 0.380
rpl-4 Protein RPL-4 0.374
ddx-19 Protein DDX-19 0.372
cyb-2.1 Protein CYB-2.1 0.371
his-6 Protein HIS-6 0.371
miro-1 Protein MIRO-1 0.370
lst-3 Protein LST-3 0.354
pabp-2 Protein PABP-2 0.347
cye-1 Protein CYE-1 0.345
pha-4 Protein PHA-4 0.338
klp-19 Protein KLP-19 0.336
F31C3.2 Protein F31C3.2 0.336
T10B11.8 Protein T10B11.8 0.329
xpo-1 Protein XPO-1 0.322
rha-1 Protein RHA-1 0.321
npp-2 Protein NPP-2 0.314
oma-2 Protein OMA-2 0.311
C48B6.3 Protein C48B6.3 0.310
Y44E3A.6 Protein Y44E3A.6 0.310
bar-1 Protein BAR-1 0.309
syx-4 Protein SYX-4 0.305
CELE_R02D3.3 Protein R02D3.3 0.300
bub-1 Protein BUB-1 0.299
R11A8.7 Protein R11A8.7 0.286
rde-2 Protein RDE-2 0.286
cdc-37 Protein CDC-37 0.283
mpk-1 Protein MPK-1 0.279
F45F2.11 Protein F45F2.11 0.277
dsh-2 Protein DSH-2 0.275
egl-30 Protein EGL-30 0.269
zyg-8 Protein ZYG-8 0.265
sec-31 Protein SEC-31 0.265
teg-4 Protein TEG-4 0.265
hlh-2 Protein HLH-2 0.263
T28D9.4 Protein T28D9.4 0.262
zyg-9 Protein ZYG-9 0.262
spd-5 Protein SPD-5 0.261
D1043.1 Protein D1043.1 0.260
zim-3 Protein ZIM-3 0.258
let-99 Protein LET-99 0.256
csn-6 Protein CSN-6 0.254
riok-2 Protein RIOK-2 0.254
F33D11.10 Protein F33D11.10 0.254
npp-16 Protein NPP-16 0.249
prp-3 Protein PRP-3 0.247
aos-1 Protein AOS-1 0.245
hcp-1 Protein HCP-1 0.240
mom-2 Protein MOM-2 0.239
sem-5 Protein SEM-5 0.239
tpxl-1 Protein TPXL-1 0.236
hcf-1 Protein HCF-1 0.234
rpl-12 Protein RPL-12 0.228
let-60 Protein LET-60 0.227
npp-3 Protein NPP-3 0.226
C16A3.4 Protein C16A3.4 0.224
eor-1 Protein EOR-1 0.224
tag-124 Protein TAG-124 0.223
ced-9 Protein CED-9 0.222
him-10 Protein HIM-10 0.221
H05C05.2 Protein H05C05.2 0.221
gld-1 Protein GLD-1 0.220
klc-1 Protein KLC-1 0.220
unc-43 Protein UNC-43 0.219
dpl-1 Protein DPL-1 0.219
daf-1 Protein DAF-1 0.215
CELE_C12D8.1 Protein C12D8.1 0.215
ire-1 Protein IRE-1 0.213
brp-1 Protein BRP-1 0.212
ZC434.8 Protein ZC434.8 0.211
set-2 Protein SET-2 0.211
F53B7.3 Protein F53B7.3 0.211
elt-6 Protein ELT-6 0.210
isw-1 Protein ISW-1 0.209
cogc-8 Protein COGC-8 0.209
csn-5 Protein CSN-5 0.208
sec-8 Protein SEC-8 0.207
hsp-16.48 Protein HSP-16.48 0.205
F56D2.6 Protein F56D2.6 0.204
hmg-4 Protein HMG-4 0.203
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Danio rerio
Name Description Probability Func Analog Organism
bmp2b bone morphogenetic protein 2b 0.803
efnb2a ephrin B2a 0.782
spry4 sprouty (Drosophila) homolog 4 0.776
sp7 Sp7 transcription factor 0.768
plk1 polo-like kinase 1 (Drosophila) 0.640
her6 hairy-related 6 0.598
mapk3 mitogen-activated protein kinase 3 0.575
tp53 tumor protein p53 0.558
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.556
dusp6 dual specificity phosphatase 6 0.552
lef1 lymphocyte enhancer binding factor 1 0.484
bcl2l1 bcl2-like 1 0.458
gro1 groucho 1 0.445
rpl35 ribosomal protein L35 0.444
her15.1 hairy and enhancer of split-related 15.1 0.429
sall4 sal-like 4 (Drosophila) 0.429
ascl1a achaete-scute complex-like 1a (Drosophila) 0.373
gdf6a growth differentiation factor 6a 0.360
wnt4a wingless-type MMTV integration site family, member 4a 0.352
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.323
per3 period homolog 3 (Drosophila) 0.316
fgf17 fibroblast growth factor 17 0.311
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.301
fgfr1a fibroblast growth factor receptor 1a 0.293
rpl36a ribosomal protein L36A 0.292
rps28 ribosomal protein S28 0.288
gata3 GATA-binding protein 3 0.280
ccna2 cyclin A2 0.266
pax6b paired box gene 6b 0.265
cxcr4b chemokine (C-X-C motif), receptor 4b 0.253
mcl1a myeloid cell leukemia sequence 1a 0.250
pkd2 polycystic kidney disease 2 0.240
myf5 myogenic factor 5 0.234
dld deltaD 0.228
ncl nucleolin 0.227
snrpd1 small nuclear ribonucleoprotein D1 polypeptide 0.226
fgfr4 fibroblast growth factor receptor 4 0.225
fn1 fibronectin 1 0.224
zgc:55813 zgc:55813 0.217
gata1a GATA binding protein 1a 0.216
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.207
ube2i ubiquitin-conjugating enzyme E2I 0.207
spry2 sprouty homolog 2 0.198
notch3 notch homolog 3 0.198
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.192
runx2b runt-related transcription factor 2b 0.192
ptgs2a prostaglandin-endoperoxide synthase 2a 0.189
dmbx1a diencephalon/mesencephalon homeobox 1a 0.187
runx2a runt-related transcription factor 2a 0.186
wnt8b wingless-type MMTV integration site family, member 8b 0.185
ncapg non-SMC condensin I complex, subunit G 0.185
brd2a bromodomain-containing 2a 0.182
rps3a ribosomal protein S3A 0.180
irx1a iroquois homeobox protein 1, a 0.177
jag2 jagged 2 0.175
pcna proliferating cell nuclear antigen 0.173
fgf4 fibroblast growth factor 4 0.172
foxa2 forkhead box A2 0.172
map2k4a mitogen-activated protein kinase kinase 4a 0.170
cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 0.170
cdt1 chromatin licensing and DNA replication factor 1 0.168
robo3 roundabout homolog 3 0.166
myod1 myogenic differentiation 1 0.164
sae1 SUMO1 activating enzyme subunit 1 0.162
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.161
rpa3 replication protein A3 0.159
notch1a notch homolog 1a 0.158
ung uracil-DNA glycosylase 0.158
bbc3 BCL2 binding component 3 0.157
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.156
ck2b casein kinase 2 beta 0.155
dtl denticleless homolog (Drosophila) 0.155
fzd7b frizzled homolog 7b 0.154
fzd7a frizzled homolog 7a 0.152
nusap1 nucleolar and spindle associated protein 1 0.151
gins3 GINS complex subunit 3 0.149
hspa5 heat shock protein 5 0.147
cav1 caveolin 1 0.145
nop58 NOP58 ribonucleoprotein homolog (yeast) 0.145
jag1b jagged 1b 0.143
ndr2 nodal-related 2 0.143
ppp2r5eb protein phosphatase 2, regulatory subunit B', epsilon isoform b 0.141
wnt5b wingless-type MMTV integration site family, member 5b 0.140
arhgap11a Rho GTPase activating protein 11A 0.138
bdnf brain-derived neurotrophic factor 0.138
fgf24 fibroblast growth factor 24 0.137
rpl28 ribosomal protein L28 0.135
dla deltaA 0.134
her11 hairy-related 11 0.134
ccnb1 cyclin B1 0.133
aurkb aurora kinase B 0.133
si:ch211-69g19.2 si:ch211-69g19.2 0.131
zgc:77714 zgc:77714 0.131
zgc:136346 zgc:136346 0.130
pax6a paired box gene 6a 0.130
cxcr4a chemokine (C-X-C motif) receptor 4a 0.129
mmp9 matrix metalloproteinase 9 0.127
gli1 GLI-Kruppel family member 1 0.126
sox4a SRY-box containing gene 4a 0.125
dkk1b dickkopf 1b 0.125
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
phl pole hole 0.996
Akt1 CG4006 gene product from transcript CG4006-RA 0.993
Ras85D Ras oncogene at 85D 0.992
asp abnormal spindle 0.992
E2f2 E2F transcription factor 2 0.983
sax saxophone 0.973
Cp190 Centrosomal protein 190kD 0.971
Mad Mothers against dpp 0.971
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.969
CycB Cyclin B 0.963
Chro Chromator 0.934
p53 CG33336 gene product from transcript CG33336-RB 0.927
Bj1 Bj1 protein 0.927
Egfr Epidermal growth factor receptor 0.923
polo CG12306 gene product from transcript CG12306-RA 0.923
Fmr1 CG6203 gene product from transcript CG6203-RC 0.922
ago archipelago 0.920
ap apterous 0.920
CSN5 COP9 complex homolog subunit 5 0.916
tkv thickveins 0.912
slmb supernumerary limbs 0.910
put punt 0.908
CG4680 CG4680 gene product from transcript CG4680-RA 0.907
da daughterless 0.903
Cdc37 CG12019 gene product from transcript CG12019-RA 0.903
dap dacapo 0.889
ctp cut up 0.881
brat brain tumor 0.876
N Notch 0.874
Sas-4 CG10061 gene product from transcript CG10061-RA 0.860
Ada2b CG9638 gene product from transcript CG9638-RA 0.855
smt3 CG4494 gene product from transcript CG4494-RA 0.844
pygo pygopus 0.842
Stat92E Signal-transducer and activator of transcription protein at 92E 0.838
ci cubitus interruptus 0.834
HLHm7 E(spl) region transcript m7 0.832
cdc2 CG5363 gene product from transcript CG5363-RA 0.820
Cdk5 Cyclin-dependent kinase 5 0.818
msn misshapen 0.794
lok loki 0.783
Iswi Imitation SWI 0.780
Nup50 Nucleoporin 50 0.779
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.760
Rbf Retinoblastoma-family protein 0.753
dpp decapentaplegic 0.751
emc extra macrochaetae 0.736
nej nejire 0.733
bsk basket 0.727
tefu telomere fusion 0.727
Pka-C1 cAMP-dependent protein kinase 1 0.725
rux roughex 0.724
orb oo18 RNA-binding protein 0.717
InR Insulin-like receptor 0.710
Int6 Int6 homologue 0.701
rap retina aberrant in pattern 0.695
CycG Cyclin G 0.687
Hdac3 Histone deacetylase 3 0.675
Khc Kinesin heavy chain 0.663
Pten CG5671 gene product from transcript CG5671-RB 0.655
Orc2 Origin recognition complex subunit 2 0.644
mus209 mutagen-sensitive 209 0.642
eg eagle 0.641
yki yorkie 0.640
shot short stop 0.638
wapl wings apart-like 0.637
rev7 CG2948 gene product from transcript CG2948-RA 0.630
pie pineapple eye 0.627
wdb widerborst 0.621
ash2 absent, small, or homeotic discs 2 0.620
CG9772 CG9772 gene product from transcript CG9772-RB 0.620
crn crooked neck 0.616
Klp67A Kinesin-like protein at 67A 0.615
Mi-2 CG8103 gene product from transcript CG8103-RA 0.613
cactin CG1676 gene product from transcript CG1676-RA 0.609
pbl pebble 0.603
numb CG3779 gene product from transcript CG3779-RB 0.601
BicD Bicaudal D 0.600
lds lodestar 0.600
mus301 mutagen-sensitive 301 0.598
SF2 CG6987 gene product from transcript CG6987-RA 0.598
sxc super sex combs 0.597
BEAF-32 Boundary element-associated factor of 32kD 0.589
tws twins 0.584
BRWD3 CG31132 gene product from transcript CG31132-RA 0.582
ncd non-claret disjunctional 0.570
Gap1 GTPase-activating protein 1 0.569
HLHmgamma E(spl) region transcript mgamma 0.567
Pcaf CG4107 gene product from transcript CG4107-RA 0.564
ovo CG6824 gene product from transcript CG6824-RE 0.560
sgg shaggy 0.559
HLHmbeta E(spl) region transcript mbeta 0.558
rl rolled 0.557
Cul-2 Cullin-2 0.556
hh hedgehog 0.554
ttv tout-velu 0.539
Rae1 CG9862 gene product from transcript CG9862-RA 0.538
Aos1 CG12276 gene product from transcript CG12276-RA 0.537
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.528
gro groucho 0.523
hipk homeodomain interacting protein kinase 0.522
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
RB1 retinoblastoma 1 1.000
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.000
BRCA1 breast cancer 1, early onset 1.000
EGFR epidermal growth factor receptor 1.000
CDK2 cyclin-dependent kinase 2 1.000
CDC20 cell division cycle 20 homolog (S. cerevisiae) 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 1.000
PLK1 polo-like kinase 1 1.000
EP300 E1A binding protein p300 1.000
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.999
HDAC1 histone deacetylase 1 0.999
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.999
CDK1 cyclin-dependent kinase 1 0.999
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.998
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.998
CCNA2 cyclin A2 0.998
XIAP X-linked inhibitor of apoptosis 0.997
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.997
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.997
SMAD2 SMAD family member 2 0.996
CCNB1 cyclin B1 0.996
AR androgen receptor 0.996
ESR1 estrogen receptor 1 0.994
JUN jun proto-oncogene 0.993
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.991
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.991
E2F1 E2F transcription factor 1 0.990
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.990
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.990
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.989
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.989
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.989
CCND1 cyclin D1 0.988
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.988
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.987
CUL3 cullin 3 0.987
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.987
GSK3B glycogen synthase kinase 3 beta 0.987
SMAD1 SMAD family member 1 0.987
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.986
AURKB aurora kinase B 0.986
CDT1 chromatin licensing and DNA replication factor 1 0.984
RBL1 retinoblastoma-like 1 (p107) 0.984
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.984
HDAC2 histone deacetylase 2 0.980
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.979
MCM7 minichromosome maintenance complex component 7 0.978
CCND3 cyclin D3 0.977
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.976
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.976
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.975
CDC25A cell division cycle 25 homolog A (S. pombe) 0.975
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.975
CSNK2B casein kinase 2, beta polypeptide 0.975
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.974
RFWD2 ring finger and WD repeat domain 2 0.972
CUL1 cullin 1 0.971
NBN nibrin 0.970
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.966
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.964
TOP2A topoisomerase (DNA) II alpha 170kDa 0.964
PML promyelocytic leukemia 0.964
SMAD3 SMAD family member 3 0.963
CCNE1 cyclin E1 0.963
RACGAP1 Rac GTPase activating protein 1 0.960
PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) 0.959
BTRC beta-transducin repeat containing 0.956
UBC ubiquitin C 0.956
TFDP1 transcription factor Dp-1 0.955
CDC25C cell division cycle 25 homolog C (S. pombe) 0.954
PPP1R12A protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.953
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.953
RBBP4 retinoblastoma binding protein 4 0.953
CDK8 cyclin-dependent kinase 8 0.953
KAT2B K(lysine) acetyltransferase 2B 0.952
SMAD4 SMAD family member 4 0.951
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.947
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.946
FOXM1 forkhead box M1 0.944
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.942
CDK6 cyclin-dependent kinase 6 0.942
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.941
PRPF3 PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) 0.941
SIRT1 sirtuin 1 0.940
CDK9 cyclin-dependent kinase 9 0.939
PRKCA protein kinase C, alpha 0.938
CUL2 cullin 2 0.934
SFN stratifin 0.934
MAPK1 mitogen-activated protein kinase 1 0.933
TSC2 tuberous sclerosis 2 0.930
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.928
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.924
SKP2 S-phase kinase-associated protein 2 (p45) 0.922
FAS Fas (TNF receptor superfamily, member 6) 0.921
RBL2 retinoblastoma-like 2 (p130) 0.921
MAPK14 mitogen-activated protein kinase 14 0.919
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.919
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.916
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Pten phosphatase and tensin homolog 1.000
Rb1 retinoblastoma 1 0.999
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.998
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.994
Apc adenomatosis polyposis coli 0.993
Brca1 breast cancer 1 0.993
Mdm2 transformed mouse 3T3 cell double minute 2 0.993
E2f1 E2F transcription factor 1 0.992
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.987
Gli3 GLI-Kruppel family member GLI3 0.981
Pax3 paired box gene 3 0.979
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.978
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.976
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.964
Smad4 MAD homolog 4 (Drosophila) 0.957
Cdk4 cyclin-dependent kinase 4 0.956
Hand1 heart and neural crest derivatives expressed transcript 1 0.955
Notch2 Notch gene homolog 2 (Drosophila) 0.955
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.951
Shh sonic hedgehog 0.951
Gli2 GLI-Kruppel family member GLI2 0.949
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.948
Ccnb1 cyclin B1 0.946
Fgfr2 fibroblast growth factor receptor 2 0.945
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.935
Rac1 RAS-related C3 botulinum substrate 1 0.932
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.930
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.923
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.916
Arid1a AT rich interactive domain 1A (SWI-like) 0.911
Per2 period homolog 2 (Drosophila) 0.909
Bax BCL2-associated X protein 0.906
Cbl Casitas B-lineage lymphoma 0.900
Atf2 activating transcription factor 2 0.895
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.895
Pthlh parathyroid hormone-like peptide 0.889
Tgfb2 transforming growth factor, beta 2 0.886
Prc1 protein regulator of cytokinesis 1 0.883
Csf1 colony stimulating factor 1 (macrophage) 0.877
Kif11 kinesin family member 11 0.874
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.873
Ccna2 cyclin A2 0.866
Thbs1 thrombospondin 1 0.863
Hes1 hairy and enhancer of split 1 (Drosophila) 0.860
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.850
Arid1b AT rich interactive domain 1B (SWI-like) 0.847
Alx4 aristaless-like homeobox 4 0.846
Akt1 thymoma viral proto-oncogene 1 0.846
Nbn nibrin 0.838
Sox2 SRY-box containing gene 2 0.834
Fos FBJ osteosarcoma oncogene 0.820
Brca2 breast cancer 2 0.815
Foxm1 forkhead box M1 0.803
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.799
Runx2 runt related transcription factor 2 0.796
Fyn Fyn proto-oncogene 0.787
Lef1 lymphoid enhancer binding factor 1 0.782
Amhr2 anti-Mullerian hormone type 2 receptor 0.779
Hcfc1 host cell factor C1 0.774
Aurkb aurora kinase B 0.769
Stag1 stromal antigen 1 0.765
Hdac1 histone deacetylase 1 0.764
Grb2 growth factor receptor bound protein 2 0.762
Hdac2 histone deacetylase 2 0.758
Grb10 growth factor receptor bound protein 10 0.756
Clock circadian locomotor output cycles kaput 0.753
Hif1a hypoxia inducible factor 1, alpha subunit 0.753
Esr1 estrogen receptor 1 (alpha) 0.750
Bcl2 B-cell leukemia/lymphoma 2 0.746
Plk1 polo-like kinase 1 (Drosophila) 0.745
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.744
Mdm4 transformed mouse 3T3 cell double minute 4 0.737
Nkx2-1 NK2 homeobox 1 0.735
Nf1 neurofibromatosis 1 0.730
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.727
Sp1 trans-acting transcription factor 1 0.722
Prrx1 paired related homeobox 1 0.721
Anln anillin, actin binding protein 0.719
Ttk Ttk protein kinase 0.715
Emx1 empty spiracles homolog 1 (Drosophila) 0.713
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.713
Sgol1 shugoshin-like 1 (S. pombe) 0.702
Pkd1 polycystic kidney disease 1 homolog 0.701
Ccnf cyclin F 0.689
Ikzf1 IKAROS family zinc finger 1 0.689
Msh2 mutS homolog 2 (E. coli) 0.680
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.679
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.678
Smc3 structural maintenace of chromosomes 3 0.677
Notch1 Notch gene homolog 1 (Drosophila) 0.675
Cdk2 cyclin-dependent kinase 2 0.674
Sox9 SRY-box containing gene 9 0.669
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.668
Smad7 MAD homolog 7 (Drosophila) 0.668
En1 engrailed 1 0.667
Meox2 mesenchyme homeobox 2 0.664
Kif23 kinesin family member 23 0.661
Snai1 snail homolog 1 (Drosophila) 0.655
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Smad7 SMAD family member 7 0.278
Dnm1l dynamin 1-like 0.253
Kif1b kinesin family member 1B 0.248
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.226
Tgfbr2 transforming growth factor, beta receptor II 0.207
Cdc42 cell division cycle 42 (GTP binding protein) 0.195
Csnk1g3 casein kinase 1, gamma 3 0.195
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.180
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.176
Jak2 Janus kinase 2 0.169
Taok1 TAO kinase 1 0.169
Top2a topoisomerase (DNA) II alpha 0.156
Homer1 homer homolog 1 (Drosophila) 0.152
Id1 inhibitor of DNA binding 1 0.152
Btg2 BTG family, member 2 0.138
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.136
Cdk2 cyclin dependent kinase 2 0.133
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.130
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.130
Lifr leukemia inhibitory factor receptor alpha 0.129
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.128
Sdc3 syndecan 3 0.124
Eif4h eukaryotic translation initiation factor 4H 0.118
Garnl1 GTPase activating Rap/RanGAP domain-like 1 0.111
Id3 inhibitor of DNA binding 3 0.105
Wdr26 WD repeat domain 26 0.104
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.104
Dusp1 dual specificity phosphatase 1 0.104
Hist1h1a histone cluster 1, H1a 0.103
Rnf4 ring finger protein 4 0.103
Nab1 Ngfi-A binding protein 1 0.092
Opcml opioid binding protein/cell adhesion molecule-like 0.090
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.090
Arf6 ADP-ribosylation factor 6 0.089
Ythdf3 YTH domain family, member 3 0.088
Ireb2 iron responsive element binding protein 2 0.087
Pfn1 profilin 1 0.087
Exoc5 exocyst complex component 5 0.085
Fgfr1 Fibroblast growth factor receptor 1 0.085
Sirpa signal-regulatory protein alpha 0.084
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.084
Rgs19 regulator of G-protein signaling 19 0.084
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.083
Tpm3 tropomyosin 3, gamma 0.083
Psg19 pregnancy specific glycoprotein 19 0.082
Nsf N-ethylmaleimide-sensitive factor 0.082
Dchs1 dachsous 1 (Drosophila) 0.081
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.081
Chrng cholinergic receptor, nicotinic, gamma 0.080
Hk1 hexokinase 1 0.079
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.079
Ube2a ubiquitin-conjugating enzyme E2A (RAD6 homolog) 0.079
Prkg2 protein kinase, cGMP-dependent, type II 0.077
Adrb1 adrenergic, beta-1-, receptor 0.076
Mapk1 mitogen activated protein kinase 1 0.075
Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 0.074
Pth parathyroid hormone 0.072
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.071
Pou2f2 POU class 2 homeobox 2 0.071
Prkcd protein kinase C, delta 0.071
Sbk1 SH3-binding domain kinase 1 0.071
Rab10 RAB10, member RAS oncogene family 0.071
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.070
Ptafr platelet-activating factor receptor 0.069
Ccne1 cyclin E1 0.069
Ccnd3 cyclin D3 0.069
Myo1b myosin Ib 0.069
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.069
Nudt3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.069
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.068
Ap2m1 adaptor-related protein complex 2, mu 1 subunit 0.068
Ptbp1 polypyrimidine tract binding protein 1 0.068
Fkbp4 FK506 binding protein 4 0.068
Klf4 Kruppel-like factor 4 (gut) 0.067
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.065
Slit3 slit homolog 3 (Drosophila) 0.065
Marcks myristoylated alanine rich protein kinase C substrate 0.065
Usp9x ubiquitin specific peptidase 9, X-linked 0.065
Thbd thrombomodulin 0.064
Nr2f6 nuclear receptor subfamily 2, group F, member 6 0.063
Jtb jumping translocation breakpoint 0.063
Arl5a ADP-ribosylation factor-like 5A 0.062
Foxm1 forkhead box M1 0.062
Gjb3 gap junction protein, beta 3 0.062
Ddr1 discoidin domain receptor tyrosine kinase 1 0.062
Phax phosphorylated adaptor for RNA export 0.061
Prlhr prolactin releasing hormone receptor 0.061
Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 0.061
Mapk3 mitogen activated protein kinase 3 0.061
Rab15 RAB15, member RAS oncogene family 0.060
Cdk4 cyclin-dependent kinase 4 0.060
Sfrs12 splicing factor, arginine/serine-rich 12 0.060
Ghsr growth hormone secretagogue receptor 0.060
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.060
Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.059
Ptprc protein tyrosine phosphatase, receptor type, C 0.059
Mpeg1 macrophage expressed 1 0.059
Vegfa vascular endothelial growth factor A 0.059
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.058
Rpl3 ribosomal protein L3 0.057