The network for 'gtp catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gtp catabolic process

The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.

Name Description Probability Func Analog Organism
YPT52 Ypt52p 0.803
GYL1 Gyl1p 0.727
GDI1 Gdi1p 0.711
RHO1 Rho1p 0.661
STE11 Ste11p 0.598
SEC4 Sec4p 0.588
YPT1 Ypt1p 0.508
YIP3 Yip3p 0.501
CDC24 Cdc24p 0.478
YPT31 Ypt31p 0.385
GCD6 Gcd6p 0.362
STE4 Ste4p 0.329
TRS65 Trs65p 0.315
MKK1 Mkk1p 0.304
VPS21 Vps21p 0.299
SEC2 Sec2p 0.284
TOR1 Tor1p 0.275
VPS15 Vps15p 0.253
SUI3 Sui3p 0.252
GCD7 Gcd7p 0.213
ROM2 Rom2p 0.193
AVO1 Avo1p 0.189
STE5 Ste5p 0.172
YPT10 Ypt10p 0.170
BET3 Bet3p 0.152
YPT6 Ypt6p 0.146
FMS1 Fms1p 0.139
TOM1 Tom1p 0.137
SSK2 Ssk2p 0.135
YPT53 Ypt53p 0.134
SPA2 Spa2p 0.130
YPT7 Ypt7p 0.127
NYV1 Nyv1p 0.120
ATG20 Atg20p 0.116
SEC13 Sec13p 0.116
SEC16 Sec16p 0.114
LSM5 Lsm5p 0.114
RFC1 Rfc1p 0.114
SEC3 Sec3p 0.110
BFR1 Bfr1p 0.105
SLM2 Slm2p 0.103
SED5 Sed5p 0.098
GIC2 Gic2p 0.097
SLT2 Slt2p 0.096
YHR127W hypothetical protein 0.094
BEM3 Bem3p 0.094
KEL1 Kel1p 0.092
PEA2 Pea2p 0.091
VPH2 Vph2p 0.089
ACK1 Ack1p 0.088
HSV2 Hsv2p 0.088
BEM2 Bem2p 0.088
KOG1 Kog1p 0.087
LTE1 Lte1p 0.086
YIP4 Yip4p 0.084
FYV8 Fyv8p 0.082
TOR2 Tor2p 0.082
GPB2 Gpb2p 0.082
CCT4 Cct4p 0.081
YPT32 Ypt32p 0.080
STE20 Ste20p 0.079
ELP4 Elp4p 0.078
VAM6 Vam6p 0.078
RAS2 Ras2p 0.077
ERV25 Erv25p 0.076
CNB1 Cnb1p 0.076
RER2 Rer2p 0.076
MSG5 Msg5p 0.076
BNI1 Bni1p 0.076
PPE1 Ppe1p 0.072
SRP54 Srp54p 0.069
SEC24 Sec24p 0.068
TRS31 Trs31p 0.068
YIP1 Yip1p 0.067
EBP2 Ebp2p 0.066
INO2 Ino2p 0.065
HYP2 Hyp2p 0.065
BUL1 Bul1p 0.065
TED1 Ted1p 0.065
YIL055C hypothetical protein 0.065
SIA1 Sia1p 0.065
BUD6 Bud6p 0.063
VPS60 Vps60p 0.062
SMM1 Smm1p 0.061
TRX1 Trx1p 0.060
TAF4 Taf4p 0.058
MNN9 Mnn9p 0.058
URA6 Ura6p 0.057
TRL1 Trl1p 0.057
PRS2 Prs2p 0.056
APM3 Apm3p 0.054
MOB2 Mob2p 0.054
FIR1 Fir1p 0.054
YHR003C hypothetical protein 0.054
SEC21 Sec21p 0.053
DNF3 Dnf3p 0.052
ISM1 Ism1p 0.052
RUD3 Rud3p 0.052
BRN1 Brn1p 0.052
YCR007C hypothetical protein 0.051
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.952
sem-5 Protein SEM-5 0.754
lag-1 Protein LAG-1 0.421
gpr-1 Protein GPR-1 0.417
CELE_W07A8.2 Protein W07A8.2 0.299
pkg-1 Protein PKG-1 0.277
mig-2 Protein MIG-2 0.269
ina-1 Protein INA-1 0.254
fhod-1 Protein FHOD-1 0.251
let-60 Protein LET-60 0.248
gpb-1 Protein GPB-1 0.206
gpr-2 Protein GPR-2 0.199
etr-1 Protein ETR-1 0.194
panl-3 Protein PANL-3 0.177
unc-26 Protein UNC-26 0.164
csnk-1 Protein CSNK-1 0.164
egl-30 Protein EGL-30 0.158
CELE_F47G4.4 Protein F47G4.4 0.146
mrck-1 Protein MRCK-1 0.141
unc-71 Protein UNC-71 0.140
sto-4 Protein STO-4 0.137
lin-45 Protein LIN-45 0.136
cmd-1 Protein CMD-1 0.129
afd-1 Protein AFD-1 0.111
C18F10.7 Protein C18F10.7 0.108
eor-2 Protein EOR-2 0.107
F52G3.1 Protein F52G3.1 0.105
stau-1 Protein STAU-1 0.102
cyld-1 Protein CYLD-1 0.101
kin-2 Protein KIN-2 0.098
let-607 Protein LET-607 0.096
rab-5 Protein RAB-5 0.095
elt-6 Protein ELT-6 0.092
CELE_F52E1.13 Protein F52E1.13 0.091
mpk-1 Protein MPK-1 0.089
nfx-1 Protein NFX-1 0.089
egrh-1 Protein EGRH-1 0.088
eef-2 Protein EEF-2 0.086
skn-1 Protein SKN-1 0.085
chc-1 Protein CHC-1 0.085
F35G2.1 Protein F35G2.1 0.083
aha-1 Protein AHA-1 0.082
frm-7 Protein FRM-7 0.082
vab-10 Protein VAB-10 0.082
sli-1 Protein SLI-1 0.081
egl-18 Protein EGL-18 0.081
vps-32.1 Protein VPS-32.1 0.080
CELE_Y53F4B.5 Protein Y53F4B.5 0.078
CELE_Y47G6A.18 Protein Y47G6A.18 0.078
ykt-6 Protein YKT-6 0.078
sel-12 Protein SEL-12 0.076
ZK154.4 Protein ZK154.4 0.076
unc-119 Protein UNC-119 0.075
ddr-2 Protein DDR-2 0.074
dpf-3 Protein DPF-3 0.072
daf-19 Protein DAF-19 0.072
vpr-1 Protein VPR-1 0.070
nra-3 Protein NRA-3 0.070
flh-2 Protein FLH-2 0.069
unc-54 Protein UNC-54 0.069
par-6 Protein PAR-6 0.068
rig-6 Protein RIG-6 0.068
CELE_C56A3.8 Protein C56A3.8 0.068
plc-3 Protein PLC-3 0.068
T28B11.1 Protein T28B11.1 0.063
sax-7 Protein SAX-7 0.063
pqn-39 Protein PQN-39 0.062
sma-9 Protein SMA-9 0.060
Y55F3BR.8 Protein Y55F3BR.8 0.059
T14G11.1 Protein T14G11.1 0.059
zoo-1 Protein ZOO-1 0.058
C11E4.6 Protein C11E4.6 0.058
pcaf-1 Protein PCAF-1 0.058
stim-1 Protein STIM-1 0.058
itr-1 Protein ITR-1 0.057
rgs-7 Protein RGS-7 0.057
CELE_Y54E10BR.5 Protein Y54E10BR.5 0.056
gei-18 Protein GEI-18 0.056
rps-2 Protein RPS-2 0.055
sam-10 Protein SAM-10 0.055
unc-116 Protein UNC-116 0.055
rars-2 Protein RARS-2 0.053
rhgf-2 Protein RHGF-2 0.053
ntl-2 Protein NTL-2 0.053
pptr-2 Protein PPTR-2 0.053
F22D3.2 Protein F22D3.2 0.052
smp-1 Protein SMP-1 0.052
dpm-1 Protein DPM-1 0.052
rme-4 Protein RME-4 0.052
atfs-1 Protein ATFS-1 0.052
ced-10 Protein CED-10 0.052
T23F11.1 Protein T23F11.1 0.051
cah-6 Protein CAH-6 0.051
F59F4.2 Protein F59F4.2 0.051
pat-3 Protein PAT-3 0.051
cdk-1 Protein CDK-1 0.050
gly-7 Protein GLY-7 0.050
lec-1 Protein LEC-1 0.050
madf-5 Protein MADF-5 0.049
CELE_T10D4.6 Protein T10D4.6 0.049
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.349
gsna gelsolin a 0.252
bida BH3 interacting domain death agonist 0.246
msna moesin a 0.233
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.226
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.216
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.199
tm9sf2 transmembrane 9 superfamily member 2 0.197
si:ch211-260p9.1 si:ch211-260p9.1 0.189
pob partial optokinetic response b 0.183
pak2a p21 (CDKN1A)-activated kinase 2a 0.179
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.177
efna1b ephrin A1b 0.174
adrb2a adrenergic receptor, beta 2a 0.173
sypl2b synaptophysin-like 2b 0.167
cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.160
rab7 RAB7, member RAS oncogene family 0.160
arf2 ADP-ribosylation factor 2 0.159
gro2 groucho 2 0.158
rps6ka3a ribosomal protein S6 kinase, polypeptide 3a 0.154
esyt3 extended synaptotagmin-like protein 3 0.150
rhoaa ras homolog gene family, member Aa 0.147
nxph1 neurexophilin 1 0.143
si:dkey-222f8.3 si:dkey-222f8.3 0.138
mcl1a myeloid cell leukemia sequence 1a 0.138
tpm4 tropomyosin 4 0.137
hars histidyl-tRNA synthetase 0.137
psen1 presenilin 1 0.133
rtcd1 RNA terminal phosphate cyclase domain 1 0.132
hn1l hematological and neurological expressed 1-like 0.130
gro1 groucho 1 0.129
zbtb4 zinc finger and BTB domain containing 4 0.128
plxnb2a plexin b2a 0.127
mcl1b myeloid cell leukemia sequence 1b 0.127
cx43 connexin 43 0.125
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.123
utp6 UTP6, small subunit (SSU) processome component, homolog (yeast) 0.122
yrk Yes-related kinase 0.122
lingo1a leucine rich repeat and Ig domain containing 1a 0.120
pvrl1b poliovirus receptor-related 1b 0.119
snx6 sorting nexin 6 0.118
stk38l serine/threonine kinase 38 like 0.116
inab internexin neuronal intermediate filament protein, alpha b 0.115
zgc:56085 zgc:56085 0.114
ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.113
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.113
scinlb scinderin like b 0.113
slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.110
bactin2 bactin2 0.110
icn ictacalcin 0.109
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.108
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.108
mtp microsomal triglyceride transfer protein 0.107
acsl4a acyl-CoA synthetase long-chain family member 4a 0.106
rab25 RAB25, member RAS oncogene family 0.106
syt5a synaptotagmin Va 0.105
LOC565839 tumor necrosis factor alpha-induced protein 2-like 0.105
rpsa ribosomal protein SA 0.103
gngt2b guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b 0.103
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.102
si:ch211-232m7.1 si:ch211-232m7.1 0.101
zgc:92392 zgc:92392 0.100
arf5 ADP-ribosylation factor 5 0.099
pnx posterior neuron-specific homeobox 0.099
slc43a1a solute carrier family 43, member 1a 0.098
bactin1 bactin1 0.098
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.096
pes pescadillo 0.094
alcamb activated leukocyte cell adhesion molecule b 0.094
gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 0.094
c10orf11 c10orf11 homolog (H. sapiens) 0.094
zgc:63831 zgc:63831 0.094
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.093
stau1 staufen, RNA binding protein, homolog 1 (Drosophila) 0.093
zgc:56272 zgc:56272 0.093
polr1c polymerase (RNA) I polypeptide C 0.092
march5l membrane-associated ring finger (C3HC4) 5, like 0.092
iqgap1 IQ motif containing GTPase activating protein 1 0.091
kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.090
dusp4 dual specificity phosphatase 4 0.090
bcl2 B-cell leukemia/lymphoma 2 0.089
zgc:77517 zgc:77517 0.089
pparg peroxisome proliferator activated receptor gamma 0.089
ube2v2 ubiquitin-conjugating enzyme E2 variant 2 0.089
rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.088
copeb core promoter element binding protein 0.088
adrb3a adrenergic receptor, beta 3a 0.087
trpc1 transient receptor potential cation channel, subfamily C, member 1 0.087
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.087
huwe1 HECT, UBA and WWE domain containing 1 0.086
rab5aa RAB5A, member RAS oncogene family, a 0.086
s100a10b S100 calcium binding protein A10b 0.085
stc1l stanniocalcin 1, like 0.085
syt13 synaptotagmin XIII 0.085
gnl3l guanine nucleotide binding protein-like 3 (nucleolar)-like 0.085
slc4a2b solute carrier family 4, anion exchanger, member 2b 0.084
ifrd2 interferon-related developmental regulator 2 0.084
shcbp1 SHC SH2-domain binding protein 1 0.084
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.083
dclk2 doublecortin-like kinase 2 0.082
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Rheb CG1081 gene product from transcript CG1081-RA 0.814
Pkn Protein kinase related to protein kinase N 0.780
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.733
Vps35 Vacuolar protein sorting 35 0.659
Rab7 Rab-protein 7 0.656
drk downstream of receptor kinase 0.653
trio CG18214 gene product from transcript CG18214-RA 0.623
pod1 CG4532 gene product from transcript CG4532-RF 0.598
ttk tramtrack 0.588
mbc myoblast city 0.540
rl rolled 0.534
Sos Son of sevenless 0.518
N Notch 0.512
Eph Eph receptor tyrosine kinase 0.512
dys dysfusion 0.436
Galpha49B G protein alpha49B 0.417
Pten CG5671 gene product from transcript CG5671-RB 0.408
Stat92E Signal-transducer and activator of transcription protein at 92E 0.391
stai stathmin 0.391
shi shibire 0.390
Ced-12 CG5336 gene product from transcript CG5336-RA 0.377
rok Rho-kinase 0.333
nwk nervous wreck 0.312
ben bendless 0.309
Pk61C Protein kinase 61C 0.305
phl pole hole 0.288
insc inscuteable 0.279
l(2)k16918 lethal (2) k16918 0.276
synj synaptojanin 0.274
Rtnl1 CG33113 gene product from transcript CG33113-RF 0.272
Rho1 CG8416 gene product from transcript CG8416-RB 0.271
Tsc1 CG6147 gene product from transcript CG6147-RA 0.259
ab abrupt 0.258
drpr draper 0.256
CG4853 CG4853 gene product from transcript CG4853-RA 0.255
mbt mushroom bodies tiny 0.248
kibra kibra ortholog 0.247
stumps CG31317 gene product from transcript CG31317-RC 0.244
CG6509 CG6509 gene product from transcript CG6509-RB 0.218
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.208
dos daughter of sevenless 0.203
baz bazooka 0.201
Gyc-89Db Guanylyl cyclase at 89Db 0.199
raps rapsynoid 0.195
CG3573 CG3573 gene product from transcript CG3573-RA 0.194
yata CG1973 gene product from transcript CG1973-RA 0.189
Gyc-89Da Guanylyl cyclase at 89Da 0.180
Mad Mothers against dpp 0.175
Flo-2 flotillin 2 0.174
Ras64B Ras oncogene at 64B 0.164
Pez CG9493 gene product from transcript CG9493-RA 0.163
Sbf SET domain binding factor 0.162
gek genghis khan 0.161
LanA Laminin A 0.161
Moe Moesin 0.155
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.152
CG17233 CG17233 gene product from transcript CG17233-RA 0.149
Vps45 Vacuolar protein sorting 45 0.147
Rala Ras-related protein 0.142
neuroligin CG13772 gene product from transcript CG13772-RA 0.140
CalpB Calpain-B 0.135
cno canoe 0.135
ninaC neither inactivation nor afterpotential C 0.135
G-ialpha65A G protein alphai subunit 65A 0.134
dm diminutive 0.131
Mtl Mig-2-like 0.131
Ephrin CG1862 gene product from transcript CG1862-RA 0.131
unc-104 CG8566 gene product from transcript CG8566-RB 0.129
NaCP60E Na channel protein 60E 0.129
chic chickadee 0.128
wkd whacked 0.127
Rab6 Rab-protein 6 0.127
siz schizo 0.126
stg string 0.125
sima similar 0.123
sec6 CG5341 gene product from transcript CG5341-RA 0.121
ics icarus 0.121
Ras85D Ras oncogene at 85D 0.120
Eip63E Ecdysone-induced protein 63E 0.120
Gad1 Glutamic acid decarboxylase 1 0.119
S6k RPS6-p70-protein kinase 0.117
Plc21C Phospholipase C at 21C 0.116
Smox Smad on X 0.115
jumu jumeau 0.111
Uba1 Ubiquitin activating enzyme 1 0.109
Su(H) Suppressor of Hairless 0.109
cher cheerio 0.105
Smg1 CG32743 gene product from transcript CG32743-RA 0.105
bbg big bang 0.102
arm armadillo 0.102
Tl Toll 0.101
CG32772 CG32772 gene product from transcript CG32772-RC 0.101
smo smoothened 0.100
cpb capping protein beta 0.098
CG7987 CG7987 gene product from transcript CG7987-RA 0.098
Khc-73 Kinesin-73 0.098
Pli Pellino 0.096
Cng Cyclic-nucleotide-gated ion channel protein 0.095
kar karmoisin 0.092
plexB plexin B 0.092
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
EGFR epidermal growth factor receptor 1.000
RAB5A RAB5A, member RAS oncogene family 1.000
OCRL oculocerebrorenal syndrome of Lowe 0.999
BCAR1 breast cancer anti-estrogen resistance 1 0.999
PTK2 PTK2 protein tyrosine kinase 2 0.999
DNM2 dynamin 2 0.999
SH3KBP1 SH3-domain kinase binding protein 1 0.999
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.998
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.998
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.997
RHOA ras homolog gene family, member A 0.997
SFN stratifin 0.996
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.996
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.996
EXOSC3 exosome component 3 0.996
DNM1 dynamin 1 0.994
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.993
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.986
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.982
SNX9 sorting nexin 9 0.980
RAB1A RAB1A, member RAS oncogene family 0.978
NCK2 NCK adaptor protein 2 0.975
GRB7 growth factor receptor-bound protein 7 0.971
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.971
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.971
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.969
SH3BP2 SH3-domain binding protein 2 0.968
ARRB2 arrestin, beta 2 0.956
SOS1 son of sevenless homolog 1 (Drosophila) 0.955
ARRB1 arrestin, beta 1 0.954
S100A11 S100 calcium binding protein A11 0.954
ITSN1 intersectin 1 (SH3 domain protein) 0.953
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.946
BBS10 Bardet-Biedl syndrome 10 0.945
RIN3 Ras and Rab interactor 3 0.943
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.930
SH3RF1 SH3 domain containing ring finger 1 0.929
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.927
NCKAP1 NCK-associated protein 1 0.926
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.920
TSC2 tuberous sclerosis 2 0.916
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.912
EEA1 early endosome antigen 1 0.910
GOLGA2 golgin A2 0.905
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.900
ABI1 abl-interactor 1 0.895
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.893
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.891
ADRBK1 adrenergic, beta, receptor kinase 1 0.890
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.890
S100B S100 calcium binding protein B 0.880
BCR breakpoint cluster region 0.874
RICTOR RPTOR independent companion of MTOR, complex 2 0.873
NCK1 NCK adaptor protein 1 0.872
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.871
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.871
S100A4 S100 calcium binding protein A4 0.871
UNC119 unc-119 homolog (C. elegans) 0.856
MYO9B myosin IXB 0.855
S100A6 S100 calcium binding protein A6 0.854
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.833
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.832
ARHGAP1 Rho GTPase activating protein 1 0.809
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.809
ARL2 ADP-ribosylation factor-like 2 0.806
FMNL1 formin-like 1 0.800
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.782
RHOG ras homolog gene family, member G (rho G) 0.770
TJP2 tight junction protein 2 (zona occludens 2) 0.755
GIMAP7 GTPase, IMAP family member 7 0.754
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.753
ILK integrin-linked kinase 0.750
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.747
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.739
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.736
GIMAP6 GTPase, IMAP family member 6 0.730
VAV1 vav 1 guanine nucleotide exchange factor 0.727
CCR5 chemokine (C-C motif) receptor 5 0.727
MARK3 MAP/microtubule affinity-regulating kinase 3 0.727
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.724
RRAGA Ras-related GTP binding A 0.722
ZYX zyxin 0.719
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.717
PLCG1 phospholipase C, gamma 1 0.713
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.712
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.710
RGS2 regulator of G-protein signaling 2, 24kDa 0.704
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.702
EEF1G eukaryotic translation elongation factor 1 gamma 0.700
FOS FBJ murine osteosarcoma viral oncogene homolog 0.696
ANK1 ankyrin 1, erythrocytic 0.696
RACGAP1 Rac GTPase activating protein 1 0.679
HIPK2 homeodomain interacting protein kinase 2 0.675
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.673
RRAGC Ras-related GTP binding C 0.669
CDK17 cyclin-dependent kinase 17 0.669
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.668
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.668
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.993
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.990
Bcl2 B-cell leukemia/lymphoma 2 0.975
Epha4 Eph receptor A4 0.971
Grb2 growth factor receptor bound protein 2 0.969
Arrb2 arrestin, beta 2 0.965
Efnb2 ephrin B2 0.964
Nf1 neurofibromatosis 1 0.953
Plxna1 plexin A1 0.939
Rac1 RAS-related C3 botulinum substrate 1 0.929
Braf Braf transforming gene 0.928
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.922
Lrrk2 leucine-rich repeat kinase 2 0.880
Eea1 early endosome antigen 1 0.875
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.865
Igtp interferon gamma induced GTPase 0.864
Ephb2 Eph receptor B2 0.863
Cbl Casitas B-lineage lymphoma 0.852
Plxnb1 plexin B1 0.850
Ntf3 neurotrophin 3 0.794
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.791
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.717
Pxn paxillin 0.716
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.693
Rasgrp1 RAS guanyl releasing protein 1 0.684
Dlg4 discs, large homolog 4 (Drosophila) 0.661
Plcg1 phospholipase C, gamma 1 0.660
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.657
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.656
Tnks1bp1 tankyrase 1 binding protein 1 0.651
Vav1 vav 1 oncogene 0.648
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.630
Ctnnb1 catenin (cadherin associated protein), beta 1 0.619
Epha1 Eph receptor A1 0.617
Rictor RPTOR independent companion of MTOR, complex 2 0.606
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.605
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.605
Cacnb3 calcium channel, voltage-dependent, beta 3 subunit 0.605
Rtkn rhotekin 0.602
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.595
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.593
Tsc1 tuberous sclerosis 1 0.588
Sox10 SRY-box containing gene 10 0.579
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.574
Dock1 dedicator of cytokinesis 1 0.563
Git1 G protein-coupled receptor kinase-interactor 1 0.563
Mapkap1 mitogen-activated protein kinase associated protein 1 0.558
Add1 adducin 1 (alpha) 0.555
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.549
Ret ret proto-oncogene 0.548
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.544
Gbp2 guanylate binding protein 2 0.531
Selplg selectin, platelet (p-selectin) ligand 0.529
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.529
Eps15 epidermal growth factor receptor pathway substrate 15 0.525
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.519
Stxbp3a syntaxin binding protein 3A 0.516
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.515
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.511
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.511
Rasa1 RAS p21 protein activator 1 0.509
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.504
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.503
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.501
Tgtp2 T-cell specific GTPase 2 0.500
Rac3 RAS-related C3 botulinum substrate 3 0.499
Fzd1 frizzled homolog 1 (Drosophila) 0.499
Mtap2 microtubule-associated protein 2 0.495
Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 0.491
Akt1 thymoma viral proto-oncogene 1 0.490
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.488
Rps3 ribosomal protein S3 0.484
Arhgef25 Rho guanine nucleotide exchange factor (GEF) 25 0.483
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.479
Cd44 CD44 antigen 0.479
Nf2 neurofibromatosis 2 0.472
Kl klotho 0.469
Shc3 src homology 2 domain-containing transforming protein C3 0.468
Kalrn kalirin, RhoGEF kinase 0.465
Hdac7 histone deacetylase 7 0.463
Plxna3 plexin A3 0.456
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.455
Mark4 MAP/microtubule affinity-regulating kinase 4 0.454
Prkcc protein kinase C, gamma 0.443
Adrbk1 adrenergic receptor kinase, beta 1 0.442
Sh3bp1 SH3-domain binding protein 1 0.439
Bcr breakpoint cluster region 0.437
Apc adenomatosis polyposis coli 0.418
Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 0.417
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.414
Ly6h lymphocyte antigen 6 complex, locus H 0.413
Ccdc64 coiled-coil domain containing 64 0.413
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.410
Dnm1 dynamin 1 0.409
Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 0.408
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.408
Phldb1 pleckstrin homology-like domain, family B, member 1 0.407
Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) 0.404
Arhgap30 Rho GTPase activating protein 30 0.404
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.401
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Arl1 ADP-ribosylation factor-like 1 0.667
Sdc3 syndecan 3 0.232
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.215
Akt1s1 AKT1 substrate 1 (proline-rich) 0.189
Ube2d3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.181
Amph amphiphysin 0.174
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.163
Snap25 synaptosomal-associated protein 25 0.161
Stxbp1 syntaxin binding protein 1 0.158
Pfn1 profilin 1 0.155
Exoc5 exocyst complex component 5 0.154
Hk1 hexokinase 1 0.149
Rhoa ras homolog gene family, member A 0.145
Rab5a RAB5A, member RAS oncogene family 0.138
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.129
Epn1 Epsin 1 0.121
Pja2 praja 2, RING-H2 motif containing 0.117
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.117
Epas1 endothelial PAS domain protein 1 0.116
Mapk3 mitogen activated protein kinase 3 0.111
Dnm1 dynamin 1 0.111
Mapk10 mitogen activated protein kinase 10 0.109
Yipf4 Yip1 domain family, member 4 0.108
Copb1 coatomer protein complex, subunit beta 1 0.106
Jtb jumping translocation breakpoint 0.100
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.098
Rhoc ras homolog gene family, member C 0.095
Bin1 bridging integrator 1 0.094
Prkch protein kinase C, eta 0.094
Sh3gl2 SH3-domain GRB2-like 2 0.092
Ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.090
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.086
Homer1 homer homolog 1 (Drosophila) 0.085
Mapk1 mitogen activated protein kinase 1 0.084
Cfp complement factor properdin 0.083
Svop SV2 related protein 0.083
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.083
Serp1 stress-associated endoplasmic reticulum protein 1 0.081
Gipc1 GIPC PDZ domain containing family, member 1 0.080
Epha7 Eph receptor A7 0.075
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.073
Csk c-src tyrosine kinase 0.072
Fgfr1 Fibroblast growth factor receptor 1 0.071
Scarb1 scavenger receptor class B, member 1 0.071
Rab6a RAB6A, member RAS oncogene family 0.070
Dlg3 discs, large homolog 3 (Drosophila) 0.070
Scn3b sodium channel, voltage-gated, type III, beta 0.070
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.070
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.068
Efhd2 EF-hand domain family, member D2 0.067
Pum1 pumilio homolog 1 (Drosophila) 0.067
Ndfip2 Nedd4 family interacting protein 2 0.066
Arpc2 actin related protein 2/3 complex, subunit 2 0.066
Sstr1 somatostatin receptor 1 0.065
RT1-DMa RT1 class II, locus DMa 0.065
Apc adenomatous polyposis coli 0.065
Gria2 glutamate receptor, ionotropic, AMPA 2 0.064
March5 membrane-associated ring finger (C3HC4) 5 0.063
Nptn neuroplastin 0.063
Anxa2 annexin A2 0.062
Nckap1 NCK-associated protein 1 0.061
Sec11a SEC11 homolog A (S. cerevisiae) 0.060
Rab2a RAB2A, member RAS oncogene family 0.060
Rab18 RAB18, member RAS oncogene family 0.059
Rab1b RAB1B, member RAS oncogene family 0.059
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.059
Nsf N-ethylmaleimide-sensitive factor 0.059
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.059
Aplp2 amyloid beta (A4) precursor-like protein 2 0.059
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.058
Arf4 ADP-ribosylation factor 4 0.058
Eef1a2 eukaryotic translation elongation factor 1 alpha 2 0.058
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.057
Itpka inositol 1,4,5-trisphosphate 3-kinase A 0.056
Pdcd10 programmed cell death 10 0.056
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.056
Sox17 SRY (sex determining region Y)-box 17 0.056
Cacnb3 calcium channel, voltage-dependent, beta 3 subunit 0.055
Mapk9 mitogen-activated protein kinase 9 0.055
Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 0.055
Klf6 Kruppel-like factor 6 0.055
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.055
Clcn2 chloride channel 2 0.053
Ap3s1 adaptor-related protein complex 3, sigma 1 subunit 0.053
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.053
Csnk1a1 casein kinase 1, alpha 1 0.053
Dlg1 discs, large homolog 1 (Drosophila) 0.052
Cryzl1 crystallin, zeta (quinone reductase)-like 1 0.051
Dapk3 death-associated protein kinase 3 0.051
Tagln2 transgelin 2 0.050
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.050
Usf2 upstream transcription factor 2, c-fos interacting 0.049
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.048
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.048
Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.048
Tmsb10 thymosin, beta 10 0.048
Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 0.047
Vps52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.047
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.047
Pcnxl3 pecanex-like 3 (Drosophila) 0.047