The network for 'dna damage checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dna damage checkpoint

A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.

Name Description Probability Func Analog Organism
PSY2 Psy2p 0.846
RAD53 Rad53p 0.841
RAD9 Rad9p 0.661
POL30 Pol30p 0.634
MEC1 Mec1p 0.589
BMH1 Bmh1p 0.439
PPH21 Pph21p 0.435
MCM5 Mcm5p 0.359
RPO26 Rpo26p 0.285
SPT5 Spt5p 0.276
RAD17 Rad17p 0.233
TOR1 Tor1p 0.230
RGC1 Rgc1p 0.191
MRC1 Mrc1p 0.183
TCO89 Tco89p 0.163
TIP41 Tip41p 0.157
FPK1 Fpk1p 0.155
CKA2 Cka2p 0.152
MCM10 Mcm10p 0.135
RFA1 Rfa1p 0.128
PSF1 Psf1p 0.121
VAC17 Vac17p 0.120
HTB1 Htb1p 0.116
SUM1 Sum1p 0.113
MCM2 Mcm2p 0.111
AHP1 Ahp1p 0.108
PDS1 Pds1p 0.107
HRK1 Hrk1p 0.106
PPH3 Pph3p 0.103
SIT4 Sit4p 0.102
PTK2 Ptk2p 0.095
TOF1 Tof1p 0.089
MCM4 Mcm4p 0.089
DBF4 Dbf4p 0.087
THO2 Tho2p 0.087
SNF1 Snf1p 0.086
DPB2 Dpb2p 0.085
DPB11 Dpb11p 0.085
MUS81 Mus81p 0.084
RRD1 Rrd1p 0.084
RAD52 Rad52p 0.082
SRS2 Srs2p 0.082
YPL260W hypothetical protein 0.080
RPB2 Rpb2p 0.079
PLC1 Plc1p 0.076
CKA1 Cka1p 0.076
REG1 Reg1p 0.075
SCS2 Scs2p 0.075
UBP8 Ubp8p 0.073
HAL5 Hal5p 0.070
EAF1 Eaf1p 0.068
MMS22 Mms22p 0.067
CRZ1 Crz1p 0.067
PAM1 Pam1p 0.066
PEX10 Pex10p 0.065
GBP2 Gbp2p 0.064
SUR1 Sur1p 0.063
MCM3 Mcm3p 0.063
CDC6 Cdc6p 0.063
SGS1 Sgs1p 0.061
RAD18 Rad18p 0.060
KIN82 Kin82p 0.059
YLR257W hypothetical protein 0.059
ASF1 Asf1p 0.058
BSC2 Bsc2p 0.058
PDR15 Pdr15p 0.057
SCH9 Sch9p 0.057
CTK1 Ctk1p 0.057
ROD1 Rod1p 0.056
HPR1 Hpr1p 0.056
CWC2 Cwc2p 0.055
RTS1 Rts1p 0.055
DED1 Ded1p 0.054
DSK2 Dsk2p 0.052
ZEO1 Zeo1p 0.052
HOG1 Hog1p 0.051
SAK1 Sak1p 0.050
RPB11 Rpb11p 0.049
RRM3 Rrm3p 0.049
SOK1 Sok1p 0.049
MMS1 Mms1p 0.049
RAD24 Rad24p 0.047
PEX22 Pex22p 0.046
CAK1 Cak1p 0.046
RPB10 Rpb10p 0.046
PRP45 Prp45p 0.046
SIR2 Sir2p 0.045
PDE2 Pde2p 0.045
RTG3 Rtg3p 0.045
HOP1 Hop1p 0.044
CHK1 Chk1p 0.044
DNA2 Dna2p 0.043
MCM6 Mcm6p 0.043
DDC1 Ddc1p 0.043
PPH22 Pph22p 0.043
DIA2 Dia2p 0.042
RTS3 Rts3p 0.041
CLB6 Clb6p 0.041
CKS1 Cks1p 0.040
ZIP1 Zip1p 0.040
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
zff9 zinc finger protein 9 0.045
ptmaa prothymosin, alpha a 0.043
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.039
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.035
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.033
xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.033
skp2 S-phase kinase-associated protein 2 (p45) 0.029
ddb2 damage-specific DNA binding protein 2 0.024
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.024
cdk8 cyclin-dependent kinase 8 0.023
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.022
hells helicase, lymphoid-specific 0.022
wdr76 WD repeat domain 76 0.021
gtdc1 glycosyltransferase-like domain containing 1 0.018
tfam transcription factor A, mitochondrial 0.018
gins2 GINS complex subunit 2 0.018
snrpd1 small nuclear ribonucleoprotein D1 polypeptide 0.018
trip13 thyroid hormone receptor interactor 13 0.017
prim1 primase polypeptide 1 0.017
per2 period homolog 2 (Drosophila) 0.016
orc6 origin recognition complex, subunit 6 0.015
chaf1b chromatin assembly factor 1, subunit B 0.015
cry5 cryptochrome 5 0.015
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.014
cry3 cryptochrome 3 0.013
anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.013
hat1 histone acetyltransferase 1 0.013
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.013
cand1 cullin-associated and neddylation-dissociated 1 0.012
nasp nuclear autoantigenic sperm protein (histone-binding) 0.012
ccna2 cyclin A2 0.012
zgc:101598 zgc:101598 0.011
ccnd1 cyclin D1 0.011
snrpc small nuclear ribonucleoprotein polypeptide C 0.011
sae1 SUMO1 activating enzyme subunit 1 0.010
ung uracil-DNA glycosylase 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
mus205 mutagen-sensitive 205 0.981
lok loki 0.972
mre11 meiotic recombination 11 0.970
Iswi Imitation SWI 0.918
CSN5 COP9 complex homolog subunit 5 0.916
cdm cadmus 0.910
mus201 mutagen-sensitive 201 0.881
spn-B spindle B 0.877
rad50 CG6339 gene product from transcript CG6339-RD 0.876
His2Av Histone H2A variant 0.861
Brca2 Breast cancer 2, early onset homolog 0.837
CDC45L CG3658 gene product from transcript CG3658-RA 0.837
Pp1-87B Protein phosphatase 1 at 87B 0.831
Rpd3 CG7471 gene product from transcript CG7471-RA 0.813
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.768
mei-9 meiotic 9 0.759
mus304 mutagen-sensitive 304 0.745
Pp2A-29B Protein phosphatase 2A at 29B 0.738
CSN4 COP9 complex homolog subunit 4 0.737
Caf1 Chromatin assembly factor 1 subunit 0.719
pic piccolo 0.707
skpA CG16983 gene product from transcript CG16983-RD 0.702
sno strawberry notch 0.695
tefu telomere fusion 0.689
eIF4AIII CG7483 gene product from transcript CG7483-RA 0.673
mus308 mutagen-sensitive 308 0.630
Ge-1 CG6181 gene product from transcript CG6181-RA 0.618
CG10754 CG10754 gene product from transcript CG10754-RA 0.601
Eip63E Ecdysone-induced protein 63E 0.575
Dp DP transcription factor 0.575
MAGE CG10059 gene product from transcript CG10059-RA 0.556
mei-41 meiotic 41 0.543
mus209 mutagen-sensitive 209 0.537
mus210 mutagen-sensitive 210 0.534
dre4 CG1828 gene product from transcript CG1828-RB 0.520
CG8159 CG8159 gene product from transcript CG8159-RB 0.514
MED6 Mediator complex subunit 6 0.487
alph alphabet 0.486
CG5524 CG5524 gene product from transcript CG5524-RA 0.474
Rev1 CG12189 gene product from transcript CG12189-RA 0.432
ssp sunspot 0.420
cdc2c CG10498 gene product from transcript CG10498-RC 0.405
mus101 mutagen-sensitive 101 0.403
glu gluon 0.401
CG6066 CG6066 gene product from transcript CG6066-RA 0.375
Irbp Inverted repeat-binding protein 0.372
MED17 Mediator complex subunit 17 0.363
mus312 mutagen-sensitive 312 0.350
key kenny 0.346
BRWD3 CG31132 gene product from transcript CG31132-RA 0.343
Srp54 CG4602 gene product from transcript CG4602-RA 0.338
Mpk2 CG5475 gene product from transcript CG5475-RB 0.331
p53 CG33336 gene product from transcript CG33336-RB 0.331
Sfmbt Scm-related gene containing four mbt domains 0.328
Pur-alpha Purine-rich binding protein-alpha 0.322
Mcm3 Minichromosome maintenance 3 0.321
MED31 Mediator complex subunit 31 0.309
MTF-1 Metal response element-binding Transcription Factor-1 0.298
RecQ5 homolog of RecQ 0.297
hay haywire 0.291
scny scrawny 0.287
pie pineapple eye 0.287
Su(var)2-HP2 CG12864 gene product from transcript CG12864-RB 0.283
CG10267 CG10267 gene product from transcript CG10267-RB 0.282
Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein 0.275
Cap-G CG34438 gene product from transcript CG34438-RF 0.268
stwl stonewall 0.267
MED20 Mediator complex subunit 20 0.265
Lnk CG17367 gene product from transcript CG17367-RC 0.264
CSN3 COP9 complex homolog subunit 3 0.258
Sir2 CG5216 gene product from transcript CG5216-RA 0.257
nbs CG6754 gene product from transcript CG6754-RC 0.256
aPKC atypical protein kinase C 0.256
Slip1 CG1783 gene product from transcript CG1783-RA 0.251
Ada2b CG9638 gene product from transcript CG9638-RA 0.251
Akt1 CG4006 gene product from transcript CG4006-RA 0.249
E2f2 E2F transcription factor 2 0.247
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.244
scra scraps 0.241
Rcd1 Reduction in Cnn dots 1 0.233
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.232
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.231
okr okra 0.230
Mes2 CG11100 gene product from transcript CG11100-RB 0.227
M6 CG7540 gene product from transcript CG7540-RA 0.218
eIF-4E Eukaryotic initiation factor 4E 0.217
Uba1 Ubiquitin activating enzyme 1 0.217
Cat Catalase 0.213
fl(2)d female lethal d 0.210
RanGap Ran GTPase activating protein 0.209
RnrL Ribonucleoside diphosphate reductase large subunit 0.207
CG14641 CG14641 gene product from transcript CG14641-RA 0.206
CG9316 CG9316 gene product from transcript CG9316-RA 0.201
imd immune deficiency 0.199
Rbf2 Retinoblastoma-family protein 2 0.194
mus301 mutagen-sensitive 301 0.194
Rpb11 CG6840 gene product from transcript CG6840-RA 0.194
lic licorne 0.191
Tip60 CG6121 gene product from transcript CG6121-RA 0.188
wde windei 0.188
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Homo sapiens
Name Description Probability Func Analog Organism
BRCA1 breast cancer 1, early onset 1.000
RB1 retinoblastoma 1 1.000
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.999
E2F1 E2F transcription factor 1 0.999
TP53 tumor protein p53 0.998
CDK2 cyclin-dependent kinase 2 0.998
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.989
THOC4 THO complex 4 0.980
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.972
PCNA proliferating cell nuclear antigen 0.970
NBN nibrin 0.967
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.949
MCM7 minichromosome maintenance complex component 7 0.930
RAD50 RAD50 homolog (S. cerevisiae) 0.930
MSH6 mutS homolog 6 (E. coli) 0.930
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.917
H2AFX H2A histone family, member X 0.914
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.901
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.895
CUL2 cullin 2 0.875
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.875
CDK8 cyclin-dependent kinase 8 0.864
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.855
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 0.850
RBBP8 retinoblastoma binding protein 8 0.837
XIAP X-linked inhibitor of apoptosis 0.796
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.767
RFWD2 ring finger and WD repeat domain 2 0.743
TFDP1 transcription factor Dp-1 0.732
UIMC1 ubiquitin interaction motif containing 1 0.718
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.702
DDB1 damage-specific DNA binding protein 1, 127kDa 0.701
FANCD2 Fanconi anemia, complementation group D2 0.694
RPA1 replication protein A1, 70kDa 0.669
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.659
RPA2 replication protein A2, 32kDa 0.640
MED1 mediator complex subunit 1 0.636
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.633
MDC1 mediator of DNA-damage checkpoint 1 0.633
ATR ataxia telangiectasia and Rad3 related 0.629
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.623
HIST1H2BG histone cluster 1, H2bg 0.610
HDAC1 histone deacetylase 1 0.603
COPS8 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) 0.595
SIRT1 sirtuin 1 0.592
UBXN7 UBX domain protein 7 0.590
MAPK14 mitogen-activated protein kinase 14 0.584
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.578
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.566
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.565
ATM ataxia telangiectasia mutated 0.560
THOC5 THO complex 5 0.559
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.546
FAM175A family with sequence similarity 175, member A 0.536
LRDD leucine-rich repeats and death domain containing 0.536
RAD18 RAD18 homolog (S. cerevisiae) 0.529
PLK1 polo-like kinase 1 0.517
TK1 thymidine kinase 1, soluble 0.464
SKP2 S-phase kinase-associated protein 2 (p45) 0.456
RFC2 replication factor C (activator 1) 2, 40kDa 0.451
MED13 mediator complex subunit 13 0.448
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.434
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.432
BABAM1 BRISC and BRCA1 A complex member 1 0.430
THOC2 THO complex 2 0.394
DDB2 damage-specific DNA binding protein 2, 48kDa 0.383
BLM Bloom syndrome, RecQ helicase-like 0.380
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.378
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.363
COPS6 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) 0.358
PARP1 poly (ADP-ribose) polymerase 1 0.355
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 0.354
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.347
SMAD7 SMAD family member 7 0.344
IER3 immediate early response 3 0.332
MSH3 mutS homolog 3 (E. coli) 0.327
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.324
GFER growth factor, augmenter of liver regeneration 0.324
DTL denticleless homolog (Drosophila) 0.324
RAD9A RAD9 homolog A (S. pombe) 0.312
KAT2B K(lysine) acetyltransferase 2B 0.311
PAX3 paired box 3 0.310
TTI1 Tel2 interacting protein 1 homolog (S. pombe) 0.303
WDR5 WD repeat domain 5 0.302
CCND1 cyclin D1 0.301
JUN jun proto-oncogene 0.298
EME1 essential meiotic endonuclease 1 homolog 1 (S. pombe) 0.296
RAD1 RAD1 homolog (S. pombe) 0.291
CUL4A cullin 4A 0.291
CNOT3 CCR4-NOT transcription complex, subunit 3 0.283
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.278
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.277
FANCA Fanconi anemia, complementation group A 0.271
RYBP RING1 and YY1 binding protein 0.271
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.268
ARRB2 arrestin, beta 2 0.266
CLSPN claspin 0.266
FOS FBJ murine osteosarcoma viral oncogene homolog 0.263
APAF1 apoptotic peptidase activating factor 1 0.262
CSNK2B casein kinase 2, beta polypeptide 0.259
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Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Pten phosphatase and tensin homolog 0.984
Mapk14 mitogen-activated protein kinase 14 0.971
Cdk4 cyclin-dependent kinase 4 0.963
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.953
Rb1 retinoblastoma 1 0.929
E2f1 E2F transcription factor 1 0.863
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.828
Clock circadian locomotor output cycles kaput 0.817
Brca2 breast cancer 2 0.805
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.803
Nbn nibrin 0.767
Msh2 mutS homolog 2 (E. coli) 0.594
Mdm2 transformed mouse 3T3 cell double minute 2 0.547
Brca1 breast cancer 1 0.534
Atm ataxia telangiectasia mutated homolog (human) 0.530
Per2 period homolog 2 (Drosophila) 0.505
Mdm4 transformed mouse 3T3 cell double minute 4 0.387
Igh immunoglobulin heavy chain complex 0.382
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.369
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.369
Skil SKI-like 0.297
Tcf3 transcription factor 3 0.288
Apc adenomatosis polyposis coli 0.256
Ncoa3 nuclear receptor coactivator 3 0.242
Atf2 activating transcription factor 2 0.239
Mapk8 mitogen-activated protein kinase 8 0.230
Cry1 cryptochrome 1 (photolyase-like) 0.227
Rpgrip1l Rpgrip1-like 0.218
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.206
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.199
Rbl1 retinoblastoma-like 1 (p107) 0.193
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.183
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.174
Pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.169
Smad4 MAD homolog 4 (Drosophila) 0.160
Timeless timeless homolog (Drosophila) 0.142
Tsc1 tuberous sclerosis 1 0.139
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.129
Daxx Fas death domain-associated protein 0.124
Parp1 poly (ADP-ribose) polymerase family, member 1 0.120
Zmym5 zinc finger, MYM-type 5 0.112
Ptch1 patched homolog 1 0.111
Cry2 cryptochrome 2 (photolyase-like) 0.110
Nae1 NEDD8 activating enzyme E1 subunit 1 0.110
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.109
Ctnnb1 catenin (cadherin associated protein), beta 1 0.109
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.104
Cdk2 cyclin-dependent kinase 2 0.095
Phc2 polyhomeotic-like 2 (Drosophila) 0.094
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.093
Trp73 transformation related protein 73 0.088
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.087
Hmgb1 high mobility group box 1 0.085
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.081
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.073
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.067
Pdpk1 3-phosphoinositide dependent protein kinase 1 0.066
Men1 multiple endocrine neoplasia 1 0.065
Mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) 0.064
Sp1 trans-acting transcription factor 1 0.062
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.061
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.060
Notch1 Notch gene homolog 1 (Drosophila) 0.060
Cops6 COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana) 0.059
Klf5 Kruppel-like factor 5 0.058
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.056
Fbxl3 F-box and leucine-rich repeat protein 3 0.056
Raf1 v-raf-leukemia viral oncogene 1 0.056
Xpa xeroderma pigmentosum, complementation group A 0.056
Lrrk2 leucine-rich repeat kinase 2 0.055
Rara retinoic acid receptor, alpha 0.053
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.053
Nf1 neurofibromatosis 1 0.052
Orc1 origin recognition complex, subunit 1 0.052
Mlh1 mutL homolog 1 (E. coli) 0.052
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.051
Fancd2 Fanconi anemia, complementation group D2 0.050
Rbbp5 retinoblastoma binding protein 5 0.050
Gpi1 glucose phosphate isomerase 1 0.050
Mll3 myeloid/lymphoid or mixed-lineage leukemia 3 0.049
Mll5 myeloid/lymphoid or mixed-lineage leukemia 5 0.047
Stag1 stromal antigen 1 0.047
Shh sonic hedgehog 0.046
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.044
Trp63 transformation related protein 63 0.044
Cbl Casitas B-lineage lymphoma 0.044
Ddx5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.043
Ube3a ubiquitin protein ligase E3A 0.043
Rrm1 ribonucleotide reductase M1 0.043
Chst8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 0.043
Foxo3 forkhead box O3 0.043
Stk11 serine/threonine kinase 11 0.042
Thbs1 thrombospondin 1 0.041
Rfc3 replication factor C (activator 1) 3 0.039
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.039
Wrn Werner syndrome homolog (human) 0.038
Ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.038
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.037
Mybl2 myeloblastosis oncogene-like 2 0.037
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Rattus norvegicus
Name Description Probability Func Analog Organism
Pebp1 phosphatidylethanolamine binding protein 1 0.026
Cdk4 cyclin-dependent kinase 4 0.022
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.020
Tcp11l2 t-complex 11 (mouse) like 2 0.017
Pkm2 pyruvate kinase, muscle 0.017
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.016
Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 0.016
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.016
Zfand6 zinc finger, AN1-type domain 6 0.016
Stxbp3 syntaxin binding protein 3 0.014
Zfand5 zinc finger, AN1-type domain 5 0.014
Slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.014
Top2b topoisomerase (DNA) II beta 0.014
Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 0.013
Cdc42 cell division cycle 42 (GTP binding protein) 0.013
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.012
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.012
Cc2d1b coiled-coil and C2 domain containing 1B 0.012
Dctn4 dynactin 4 0.012
Xiap X-linked inhibitor of apoptosis 0.012
Oaz1 ornithine decarboxylase antizyme 1 0.012
Mcm6 minichromosome maintenance complex component 6 0.011
Ptbp1 polypyrimidine tract binding protein 1 0.011
Lin7c lin-7 homolog C (C. elegans) 0.011
Rbbp7 retinoblastoma binding protein 7 0.011
Gstp1 glutathione S-transferase pi 1 0.011
Mak10 MAK10 homolog, amino-acid N-acetyltransferase subunit, (S. cerevisiae) 0.011
Pfn1 profilin 1 0.011
Mbtps1 membrane-bound transcription factor peptidase, site 1 0.011
Polr2b polymerase (RNA) II (DNA directed) polypeptide B 0.011
Rcc2 regulator of chromosome condensation 2 0.011
Stub1 STIP1 homology and U-Box containing protein 1 0.011
Bad BCL2-associated agonist of cell death 0.011
Dlg3 discs, large homolog 3 (Drosophila) 0.010
Setd2 SET domain containing 2 0.010
Tcf12 transcription factor 12 0.010
Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.010
Mxi1 MAX interactor 1 0.010
Gnas GNAS complex locus 0.010
Raf1 v-raf-leukemia viral oncogene 1 0.010
H2afx H2A histone family, member X 0.010
Ube2a ubiquitin-conjugating enzyme E2A (RAD6 homolog) 0.010
Rpa2 replication protein A2 0.010
Rad54l RAD54 like (S. cerevisiae) 0.010
Cul3 cullin 3 0.010
Atf2 activating transcription factor 2 0.010
Ttc13 tetratricopeptide repeat domain 13 0.010
Fanca Fanconi anemia, complementation group A 0.010
Dkc1 dyskeratosis congenita 1, dyskerin 0.010
Rb1 retinoblastoma 1 0.010
Hnrpdl heterogeneous nuclear ribonucleoprotein D-like 0.010