The network for 'cell cycle g1 s phase transition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell cycle g1 s phase transition

The cell cycle process by which a cell in G1 phase commits to S phase.

Name Description Probability Func Analog Organism
CDC28 Cdc28p 0.941
CLN1 Cln1p 0.827
CKS1 Cks1p 0.721
CLB2 Clb2p 0.721
CDC6 Cdc6p 0.710
HHO1 Hho1p 0.696
WHI5 Whi5p 0.597
SWI6 Swi6p 0.587
CLB5 Clb5p 0.539
SPT16 Spt16p 0.525
CDC4 Cdc4p 0.488
RTF1 Rtf1p 0.487
KSP1 Ksp1p 0.484
SWI5 Swi5p 0.447
MBP1 Mbp1p 0.380
PPH22 Pph22p 0.380
PPH21 Pph21p 0.373
CLN2 Cln2p 0.370
CLN3 Cln3p 0.356
RAD53 Rad53p 0.354
NDD1 Ndd1p 0.343
SWI4 Swi4p 0.343
MSA2 Msa2p 0.332
MSA1 Msa1p 0.329
SKP1 Skp1p 0.328
SET2 Set2p 0.327
CDC53 Cdc53p 0.322
CDC34 Cdc34p 0.319
RSC4 Rsc4p 0.307
SIT4 Sit4p 0.300
CDC12 Cdc12p 0.294
PSR2 Psr2p 0.293
RSC8 Rsc8p 0.288
SIC1 Sic1p 0.287
FKH2 Fkh2p 0.281
SIN3 Sin3p 0.266
MCM1 Mcm1p 0.253
TOR2 Tor2p 0.214
PBS2 Pbs2p 0.209
HIR1 Hir1p 0.196
PSK1 Psk1p 0.191
HAL5 Hal5p 0.178
PSR1 Psr1p 0.174
MIG1 Mig1p 0.166
RTS3 Rts3p 0.166
DPB2 Dpb2p 0.163
NPL6 Npl6p 0.163
VID24 Vid24p 0.162
SLG1 Slg1p 0.161
CDC14 Cdc14p 0.161
CLB1 Clb1p 0.158
YHP1 Yhp1p 0.158
NET1 Net1p 0.152
SFG1 Sfg1p 0.151
TAP42 Tap42p 0.149
TIF4632 Tif4632p 0.148
MSN4 Msn4p 0.144
NRM1 Nrm1p 0.144
MIG2 Mig2p 0.143
TOR1 Tor1p 0.141
SAP190 Sap190p 0.140
SPC98 Spc98p 0.137
MYO2 Myo2p 0.137
HCM1 Hcm1p 0.131
UME1 Ume1p 0.128
CDC21 Cdc21p 0.125
PPH3 Pph3p 0.123
YNL194C hypothetical protein 0.122
HDA2 Hda2p 0.121
BEM3 Bem3p 0.118
MUS81 Mus81p 0.118
SLD2 Sld2p 0.117
CLB6 Clb6p 0.117
SPT5 Spt5p 0.116
MMR1 Mmr1p 0.114
YKR075C hypothetical protein 0.113
YPL014W hypothetical protein 0.111
RSC6 Rsc6p 0.110
PTK2 Ptk2p 0.110
TAF2 Taf2p 0.106
CTI6 Cti6p 0.106
CDC10 Cdc10p 0.106
SAP185 Sap185p 0.105
KEL1 Kel1p 0.103
YJU2 Yju2p 0.102
CKB1 Ckb1p 0.096
NUP157 Nup157p 0.095
MOT1 Mot1p 0.095
AFT1 Aft1p 0.095
SAP155 Sap155p 0.094
ORC6 Orc6p 0.090
BUD4 Bud4p 0.090
HRK1 Hrk1p 0.090
CLB3 Clb3p 0.088
PCL1 Pcl1p 0.088
TIP41 Tip41p 0.087
CSR2 Csr2p 0.087
ESP1 Esp1p 0.086
CKA1 Cka1p 0.085
FAR1 Far1p 0.085
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
pha-4 Protein PHA-4 0.032
let-60 Protein LET-60 0.029
mix-1 Protein MIX-1 0.028
swsn-7 Protein SWSN-7 0.028
npp-1 Protein NPP-1 0.026
atg-18 Protein ATG-18 0.026
hif-1 Protein HIF-1 0.024
ttr-15 Protein TTR-15 0.024
K03H4.2 Protein K03H4.2 0.023
kin-29 Protein KIN-29 0.023
cfim-2 Protein CFIM-2 0.022
sem-5 Protein SEM-5 0.022
ncbp-2 Protein NCBP-2 0.021
gon-2 Protein GON-2 0.021
F31D4.2 Protein F31D4.2 0.021
csn-5 Protein CSN-5 0.021
elt-6 Protein ELT-6 0.020
lig-1 Protein LIG-1 0.020
ced-9 Protein CED-9 0.020
trr-1 Protein TRR-1 0.020
sli-1 Protein SLI-1 0.020
K10C3.4 Protein K10C3.4 0.019
Y44E3A.6 Protein Y44E3A.6 0.019
eya-1 Protein EYA-1 0.019
W01F3.2 Protein W01F3.2 0.019
ergo-1 Protein ERGO-1 0.019
F37C4.5 Protein F37C4.5 0.019
vpr-1 Protein VPR-1 0.019
B0507.2 Protein B0507.2 0.019
ubc-25 Protein UBC-25 0.018
sel-12 Protein SEL-12 0.018
swsn-3 Protein SWSN-3 0.018
W05F2.6 Protein W05F2.6 0.018
elc-1 Protein ELC-1 0.017
lin-45 Protein LIN-45 0.017
M01E5.3 Protein M01E5.3 0.017
R05D3.2 Protein R05D3.2 0.017
sdc-1 Protein SDC-1 0.017
R05F9.9 Protein R05F9.9 0.017
Y71H2B.2 Protein Y71H2B.2 0.017
egl-18 Protein EGL-18 0.017
xpo-1 Protein XPO-1 0.017
pbrm-1 Protein PBRM-1 0.017
cpt-1 Protein CPT-1 0.017
eef-1G Protein EEF-1G 0.016
C10G11.7 Protein C10G11.7 0.016
sel-8 Protein SEL-8 0.016
B0205.1 Protein B0205.1 0.016
cdt-1 Protein CDT-1 0.016
T18D3.1 Protein T18D3.1 0.016
CELE_C50B6.3 Protein C50B6.3 0.016
sos-1 Protein SOS-1 0.016
rpl-16 Protein RPL-16 0.016
npp-8 Protein NPP-8 0.016
ced-4 Protein CED-4 0.016
plc-3 Protein PLC-3 0.016
smg-8 Protein SMG-8 0.016
CELE_F54D5.5 Protein F54D5.5 0.016
rpn-3 Protein RPN-3 0.016
lin-12 Protein LIN-12 0.016
pde-2 Protein PDE-2 0.016
CELE_F20D1.1 Protein F20D1.1 0.016
zim-1 Protein ZIM-1 0.016
flt-1 Protein FLT-1 0.015
pvf-1 Protein PVF-1 0.015
ttr-2 Protein TTR-2 0.015
K02A11.3 Protein K02A11.3 0.015
magi-1 Protein MAGI-1 0.015
rfc-4 Protein RFC-4 0.015
iff-1 Protein IFF-1 0.015
pqn-59 Protein PQN-59 0.015
F32A5.4 Protein F32A5.4 0.015
W01D2.1 Protein W01D2.1 0.015
ensa-1 Protein ENSA-1 0.015
tra-4 Protein TRA-4 0.015
zwl-1 Protein ZWL-1 0.015
asd-1 Protein ASD-1 0.015
rsd-6 Protein RSD-6 0.015
CELE_F59H5.1 Protein F59H5.1 0.015
hrp-1 Protein HRP-1 0.015
dpy-21 Protein DPY-21 0.015
hmg-4 Protein HMG-4 0.015
M02D8.3 Protein M02D8.3 0.015
unc-108 Protein UNC-108 0.015
flh-1 Protein FLH-1 0.015
lag-1 Protein LAG-1 0.014
fox-1 Protein FOX-1 0.014
mat-3 Protein MAT-3 0.014
T20B12.7 Protein T20B12.7 0.014
F39B2.1 Protein F39B2.1 0.014
C48B6.3 Protein C48B6.3 0.014
ucr-2.3 Protein UCR-2.3 0.014
hpo-9 Protein HPO-9 0.014
rgs-7 Protein RGS-7 0.014
ppfr-4 Protein PPFR-4 0.014
air-1 Protein AIR-1 0.014
cand-1 Protein CAND-1 0.014
hsp-43 Protein HSP-43 0.014
sto-4 Protein STO-4 0.014
npp-15 Protein NPP-15 0.014
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.744
itgb1b.2 integrin, beta 1b.2 0.730
tp53 tumor protein p53 0.396
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.331
tal1 T-cell acute lymphocytic leukemia 1 0.325
itgb1a integrin, beta 1a 0.300
chd chordin 0.267
gata3 GATA-binding protein 3 0.245
cx43 connexin 43 0.243
orc6 origin recognition complex, subunit 6 0.237
ptgs2a prostaglandin-endoperoxide synthase 2a 0.234
smo smoothened homolog (Drosophila) 0.232
id1 inhibitor of DNA binding 1 0.226
zgc:165373 zgc:165373 0.220
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.208
gli2a GLI-Kruppel family member GLI2a 0.192
fzd7b frizzled homolog 7b 0.190
igf1rb insulin-like growth factor 1b receptor 0.188
gsna gelsolin a 0.187
sox11a SRY-box containing gene 11a 0.180
anxa1b annexin A1b 0.176
axin1 axin 1 0.175
zff9 zinc finger protein 9 0.175
si:dkeyp-113d7.7 si:dkeyp-113d7.7 0.170
tipin timeless interacting protein 0.170
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.167
lfng lunatic fringe homolog 0.165
rpa3 replication protein A3 0.156
ip6k2 inositol hexaphosphate kinase 2 0.156
fancd2 Fanconi anemia, complementation group D2 0.154
LOC566708 FL cytokine receptor-like 0.154
inha inhibin, alpha 0.152
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.151
tbx1 T-box 1 0.150
gata1a GATA binding protein 1a 0.149
stmn1b stathmin 1b 0.148
gro2 groucho 2 0.144
pld1a phospholipase D1a 0.142
sox3 SRY-box containing gene 3 0.139
slbp stem-loop binding protein 0.136
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.133
itgb1b integrin, beta 1b 0.132
gmnn geminin, DNA replication inhibitor 0.132
klf2a Kruppel-like factor 2a 0.129
cfl2l cofilin 2, like 0.124
fam84a family with sequence similarity 84, member A 0.117
ncor1 nuclear receptor co-repressor 1 0.115
itgb1b.1 integrin, beta 1b.1 0.115
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.109
tspan7b tetraspanin 7b 0.109
wu:fb76c12 wu:fb76c12 0.108
zgc:92061 zgc:92061 0.108
hoxd4a homeo box D4a 0.107
cdc25 cell division cycle 25 homolog 0.105
tgfb1a transforming growth factor, beta 1a 0.105
smad5 MAD homolog 5 (Drosophila) 0.104
cdc42l cell division cycle 42, like 0.104
mos v-mos Moloney murine sarcoma viral oncogene homolog 0.103
ccne cyclin E 0.102
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.102
foxi1 forkhead box I1 0.100
dnmt7 DNA (cytosine-5-)-methyltransferase 7 0.100
rbpms2 RNA binding protein with multiple splicing 2 0.100
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.099
tomm34 translocase of outer mitochondrial membrane 34 0.099
zgc:110113 zgc:110113 0.099
pou3f1 POU class 3 homeobox 1 0.099
ccnd1 cyclin D1 0.098
lpp LIM domain containing preferred translocation partner in lipoma 0.096
icn2 ictacalcin 2 0.095
fmr1 fragile X mental retardation 1 0.094
pou5f1 POU domain, class 5, transcription factor 1 0.093
rac3a ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3) 0.093
ass1 argininosuccinate synthetase 1 0.092
mapk3 mitogen-activated protein kinase 3 0.092
foxb1.2 forkhead box B1.2 0.091
ptger4a prostaglandin E receptor 4 (subtype EP4) a 0.091
ndnl2 necdin-like 2 0.091
ppargc1al peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like 0.088
myca myelocytomatosis oncogene a 0.088
sox19a SRY-box containing gene 19a 0.088
znf503 zinc finger protein 503 0.087
zgc:153910 zgc:153910 0.087
rspo3 R-spondin 3 homolog (Xenopus laevis) 0.087
dlc deltaC 0.086
gtf2b general transcription factor IIB 0.086
LOC100151531 zinc finger protein Gfi-1b-like 0.085
prdm5 PR domain containing 5 0.085
ptmaa prothymosin, alpha a 0.085
btg2 B-cell translocation gene 2 0.083
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.083
hs3st3b1a heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a 0.082
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.081
snrpb2 small nuclear ribonucleoprotein polypeptide B2 0.081
kirrel3l kin of IRRE like 3 like 0.080
mcmbp minichromosome maintenance complex binding protein 0.080
zgc:73142 zgc:73142 0.080
rbb4 retinoblastoma binding protein 4 0.080
nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.080
zgc:91835 zgc:91835 0.080
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.971
Akt1 CG4006 gene product from transcript CG4006-RA 0.948
phl pole hole 0.801
CycE Cyclin E 0.771
Stat92E Signal-transducer and activator of transcription protein at 92E 0.750
hep hemipterous 0.662
Rbf Retinoblastoma-family protein 0.641
tkv thickveins 0.635
dap dacapo 0.498
brm brahma 0.454
dm diminutive 0.435
Cdk4 Cyclin-dependent kinase 4 0.433
EcR Ecdysone receptor 0.353
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.340
shn schnurri 0.296
Pk61C Protein kinase 61C 0.296
cdc2c CG10498 gene product from transcript CG10498-RC 0.231
Pten CG5671 gene product from transcript CG5671-RB 0.229
ci cubitus interruptus 0.225
CycA Cyclin A 0.206
CycB3 Cyclin B3 0.206
polybromo CG11375 gene product from transcript CG11375-RA 0.201
kay kayak 0.185
emc extra macrochaetae 0.179
heph hephaestus 0.176
gig gigas 0.174
RASSF8 CG5053 gene product from transcript CG5053-RA 0.171
rap retina aberrant in pattern 0.164
Smr Smrter 0.158
cdc2 CG5363 gene product from transcript CG5363-RA 0.143
nej nejire 0.139
brat brain tumor 0.129
bun bunched 0.124
Mad Mothers against dpp 0.120
RfC3 Replication factor C subunit 3 0.119
how held out wings 0.108
Mer Merlin 0.107
sd scalloped 0.106
myoglianin CG1838 gene product from transcript CG1838-RD 0.104
CycG Cyclin G 0.097
Tor Target of rapamycin 0.096
rho rhomboid 0.091
Rm62 CG10279 gene product from transcript CG10279-RD 0.091
stg string 0.091
sax saxophone 0.088
ftz-f1 ftz transcription factor 1 0.083
Gap1 GTPase-activating protein 1 0.083
InR Insulin-like receptor 0.082
gbb glass bottom boat 0.080
l(1)dd4 lethal (1) discs degenerate 4 0.078
Pp2B-14D Protein phosphatase 2B at 14D 0.078
yki yorkie 0.078
RPA2 Replication protein A2 0.071
RpL39 Ribosomal protein L39 0.071
Tl Toll 0.070
Pc Polycomb 0.066
osa CG7467 gene product from transcript CG7467-RD 0.065
mip120 Myb-interacting protein 120 0.064
Dp DP transcription factor 0.064
fu fused 0.064
cid centromere identifier 0.062
emb embargoed 0.061
drk downstream of receptor kinase 0.061
arm armadillo 0.060
Gug Grunge 0.060
RfC4 Replication factor C subunit 4 0.058
CG10417 CG10417 gene product from transcript CG10417-RA 0.058
Ntf-2 Nuclear transport factor-2 0.056
Cks30A Cyclin-dependent kinase subunit 30A 0.056
MED26 Mediator complex subunit 26 0.056
Pabp2 CG2163 gene product from transcript CG2163-RA 0.055
Sos Son of sevenless 0.054
JhI-1 Juvenile hormone-inducible protein 1 0.054
MED17 Mediator complex subunit 17 0.053
CG4567 CG4567 gene product from transcript CG4567-RA 0.053
S6k RPS6-p70-protein kinase 0.053
Cbl CG7037 gene product from transcript CG7037-RB 0.052
Cp190 Centrosomal protein 190kD 0.052
put punt 0.051
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.050
krz kurtz 0.050
Psf2 CG18013 gene product from transcript CG18013-RA 0.049
e(y)3 enhancer of yellow 3 0.049
Tsc1 CG6147 gene product from transcript CG6147-RA 0.048
dod dodo 0.048
Grip84 gamma-tubulin ring protein 84 0.048
pan pangolin 0.048
mad2 CG17498 gene product from transcript CG17498-RA 0.046
CG7544 CG7544 gene product from transcript CG7544-RA 0.046
SAK Sak kinase 0.045
snRNP-U1-70K small ribonucleoprotein particle U1 subunit 70K 0.045
asf1 anti-silencing factor 1 0.045
Rel Relish 0.045
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.044
rno rhinoceros 0.043
Rab11 Rab-protein 11 0.043
ebi CG4063 gene product from transcript CG4063-RA 0.042
ed echinoid 0.042
RnrS Ribonucleoside diphosphate reductase small subunit 0.042
rl rolled 0.042
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDK2 cyclin-dependent kinase 2 0.986
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.985
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.976
RB1 retinoblastoma 1 0.964
CCNE1 cyclin E1 0.907
RBL2 retinoblastoma-like 2 (p130) 0.882
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.879
RBL1 retinoblastoma-like 1 (p107) 0.878
BRCA1 breast cancer 1, early onset 0.871
TP53 tumor protein p53 0.863
SKP2 S-phase kinase-associated protein 2 (p45) 0.852
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.828
YAP1 Yes-associated protein 1 0.804
JAG1 jagged 1 0.780
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.750
CDK6 cyclin-dependent kinase 6 0.726
CCND1 cyclin D1 0.665
BTRC beta-transducin repeat containing 0.647
FGFR2 fibroblast growth factor receptor 2 0.645
XIAP X-linked inhibitor of apoptosis 0.633
SMAD7 SMAD family member 7 0.632
SMAD3 SMAD family member 3 0.615
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.607
CCND3 cyclin D3 0.593
CCNA2 cyclin A2 0.588
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.562
CDT1 chromatin licensing and DNA replication factor 1 0.551
CUL1 cullin 1 0.518
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.470
ARID1A AT rich interactive domain 1A (SWI-like) 0.430
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.428
CDK1 cyclin-dependent kinase 1 0.418
GSK3B glycogen synthase kinase 3 beta 0.414
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.413
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.405
E2F1 E2F transcription factor 1 0.383
E2F7 E2F transcription factor 7 0.377
FOXM1 forkhead box M1 0.368
FAS Fas (TNF receptor superfamily, member 6) 0.365
NOTCH1 notch 1 0.350
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.344
FKBP1A FK506 binding protein 1A, 12kDa 0.329
SMC3 structural maintenance of chromosomes 3 0.308
E2F8 E2F transcription factor 8 0.307
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.302
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.301
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.291
CKS1B CDC28 protein kinase regulatory subunit 1B 0.282
CUL2 cullin 2 0.273
PRNP prion protein 0.268
TGFB1 transforming growth factor, beta 1 0.255
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.250
ABI2 abl-interactor 2 0.236
CDK4 cyclin-dependent kinase 4 0.234
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.220
EP300 E1A binding protein p300 0.215
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.205
BCOR BCL6 corepressor 0.203
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.200
MCM7 minichromosome maintenance complex component 7 0.199
TK1 thymidine kinase 1, soluble 0.198
SMAD4 SMAD family member 4 0.198
HEXIM1 hexamethylene bis-acetamide inducible 1 0.196
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.195
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.193
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.190
MYBL2 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 0.184
NCOA1 nuclear receptor coactivator 1 0.183
EIF4E eukaryotic translation initiation factor 4E 0.171
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.169
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.164
RPTOR regulatory associated protein of MTOR, complex 1 0.163
INADL InaD-like (Drosophila) 0.159
CCNE2 cyclin E2 0.155
TFDP1 transcription factor Dp-1 0.145
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.142
LIN9 lin-9 homolog (C. elegans) 0.140
CCNB2 cyclin B2 0.134
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.133
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.133
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.132
PLK1 polo-like kinase 1 0.131
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.128
SKP1 S-phase kinase-associated protein 1 0.120
APAF1 apoptotic peptidase activating factor 1 0.114
FASLG Fas ligand (TNF superfamily, member 6) 0.114
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.113
AHR aryl hydrocarbon receptor 0.112
CSNK1A1 casein kinase 1, alpha 1 0.110
SUFU suppressor of fused homolog (Drosophila) 0.109
NOXA1 NADPH oxidase activator 1 0.108
ACTN2 actinin, alpha 2 0.107
MAPK14 mitogen-activated protein kinase 14 0.106
CCNB1 cyclin B1 0.103
SETD7 SET domain containing (lysine methyltransferase) 7 0.103
SMN1 survival of motor neuron 1, telomeric 0.102
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.098
AR androgen receptor 0.097
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.095
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 125kDa 0.095
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Rb1 retinoblastoma 1 0.988
Mdm2 transformed mouse 3T3 cell double minute 2 0.945
E2f1 E2F transcription factor 1 0.918
Cdk4 cyclin-dependent kinase 4 0.886
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.855
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.818
Cdk2 cyclin-dependent kinase 2 0.796
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.768
Apc adenomatosis polyposis coli 0.688
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.525
Mdm4 transformed mouse 3T3 cell double minute 4 0.514
Notch1 Notch gene homolog 1 (Drosophila) 0.497
Tgfb2 transforming growth factor, beta 2 0.484
Cdt1 chromatin licensing and DNA replication factor 1 0.479
Arid1b AT rich interactive domain 1B (SWI-like) 0.468
Cbl Casitas B-lineage lymphoma 0.461
Nfatc3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.459
Ccnd1 cyclin D1 0.459
Cdk6 cyclin-dependent kinase 6 0.448
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.433
Nf1 neurofibromatosis 1 0.433
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.413
Fgfr1 fibroblast growth factor receptor 1 0.398
Shc1 src homology 2 domain-containing transforming protein C1 0.381
Ccne1 cyclin E1 0.379
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.355
Bax BCL2-associated X protein 0.332
Bcl2 B-cell leukemia/lymphoma 2 0.331
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.311
Birc5 baculoviral IAP repeat-containing 5 0.287
Cdkn2d cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.251
Hes1 hairy and enhancer of split 1 (Drosophila) 0.239
Pten phosphatase and tensin homolog 0.224
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.210
Grb2 growth factor receptor bound protein 2 0.208
Ccnd2 cyclin D2 0.181
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.181
Runx1 runt related transcription factor 1 0.178
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.166
Meox2 mesenchyme homeobox 2 0.164
Mybl2 myeloblastosis oncogene-like 2 0.164
Tcf3 transcription factor 3 0.162
Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.152
Lgals3 lectin, galactose binding, soluble 3 0.149
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.148
Rara retinoic acid receptor, alpha 0.147
Cd80 CD80 antigen 0.144
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.143
Mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) 0.142
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.138
Pcna proliferating cell nuclear antigen 0.136
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.131
Dlg4 discs, large homolog 4 (Drosophila) 0.130
Ccnf cyclin F 0.128
Thbs1 thrombospondin 1 0.128
Gab1 growth factor receptor bound protein 2-associated protein 1 0.127
Dkc1 dyskeratosis congenita 1, dyskerin homolog (human) 0.127
Brca2 breast cancer 2 0.125
Gmnn geminin 0.123
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.123
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.123
S100a11 S100 calcium binding protein A11 (calgizzarin) 0.119
Gtse1 G two S phase expressed protein 1 0.118
Eif2c1 eukaryotic translation initiation factor 2C, 1 0.116
Socs1 suppressor of cytokine signaling 1 0.114
Kit kit oncogene 0.113
Dysf dysferlin 0.111
Shh sonic hedgehog 0.109
Fgfr2 fibroblast growth factor receptor 2 0.109
Rfc5 replication factor C (activator 1) 5 0.108
Tcf4 transcription factor 4 0.107
Rbl1 retinoblastoma-like 1 (p107) 0.104
Plk1 polo-like kinase 1 (Drosophila) 0.103
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.100
Inhbb inhibin beta-B 0.098
Ctnnb1 catenin (cadherin associated protein), beta 1 0.097
Stk4 serine/threonine kinase 4 0.097
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.096
Pofut1 protein O-fucosyltransferase 1 0.095
Smn1 survival motor neuron 1 0.095
Pbx1 pre B-cell leukemia transcription factor 1 0.095
Ccna2 cyclin A2 0.094
Msh2 mutS homolog 2 (E. coli) 0.093
Gja1 gap junction protein, alpha 1 0.093
Spnb2 spectrin beta 2 0.090
Prc1 protein regulator of cytokinesis 1 0.088
Smad4 MAD homolog 4 (Drosophila) 0.088
Ptch1 patched homolog 1 0.088
Cdca5 cell division cycle associated 5 0.088
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.086
Tfdp2 transcription factor Dp 2 0.086
Ncapd2 non-SMC condensin I complex, subunit D2 0.085
Arid1a AT rich interactive domain 1A (SWI-like) 0.083
Pdcd1 programmed cell death 1 0.083
Mtf2 metal response element binding transcription factor 2 0.083
Braf Braf transforming gene 0.082
Marveld1 MARVEL (membrane-associating) domain containing 1 0.082
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.081
Klf3 Kruppel-like factor 3 (basic) 0.080
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Top2a topoisomerase (DNA) II alpha 0.549
Traf4af1 TRAF4 associated factor 1 0.173
Ccnd1 cyclin D1 0.102
Pttg1 pituitary tumor-transforming 1 0.074
Cdk2 cyclin dependent kinase 2 0.066
Arhgap11a Rho GTPase activating protein 11A 0.061
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.056
Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.054
Usf2 upstream transcription factor 2, c-fos interacting 0.051
Prkce protein kinase C, epsilon 0.051
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.047
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.044
Kif2c kinesin family member 2C 0.044
Cntn3 contactin 3 (plasmacytoma associated) 0.042
Ube2c ubiquitin-conjugating enzyme E2C 0.041
Smad2 SMAD family member 2 0.040
Lmnb1 lamin B1 0.039
Tk1 thymidine kinase 1, soluble 0.038
Ect2 epithelial cell transforming sequence 2 oncogene 0.035
Kif22 kinesin family member 22 0.034
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.033
Mcm6 minichromosome maintenance complex component 6 0.033
Cnbp CCHC-type zinc finger, nucleic acid binding protein 0.033
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.031
Metap2 methionyl aminopeptidase 2 0.030
Whsc2 Wolf-Hirschhorn syndrome candidate 2 (human) 0.029
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.027
Tp53 tumor protein p53 0.027
Mcm3 minichromosome maintenance complex component 3 0.027
Kifc1 kinesin family member C1 0.027
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.026
Bmp7 bone morphogenetic protein 7 0.026
Nfix nuclear factor I/X (CCAAT-binding transcription factor) 0.025
Ccnd2 cyclin D2 0.024
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.024
Ccne1 cyclin E1 0.023
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.022
Camkv CaM kinase-like vesicle-associated 0.022
Ccnd3 cyclin D3 0.022
Hoxa1 homeo box A1 0.021
Foxm1 forkhead box M1 0.021
Cdca3 cell division cycle associated 3 0.020
Mapk7 mitogen-activated protein kinase 7 0.020
Nup88 nucleoporin 88 0.020
Tcfe2a transcription factor E2a 0.020
Ptger3 prostaglandin E receptor 3 (subtype EP3) 0.020
Ptprc protein tyrosine phosphatase, receptor type, C 0.020
Foxi2 forkhead box I2 0.019
Npy1r neuropeptide Y receptor Y1 0.019
Rpa2 replication protein A2 0.018
Glra3 glycine receptor, alpha 3 0.018
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.018
Efnb1 ephrin B1 0.017
Caprin1 cell cycle associated protein 1 0.017
Slfn2 schlafen 2 0.017
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.017
Rrm2 ribonucleotide reductase M2 0.017
Tmpo thymopoietin 0.017
Ptprs protein tyrosine phosphatase, receptor type, S 0.017
Csda cold shock domain protein A 0.017
Apba3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.017
Dnah9 dynein, axonemal, heavy polypeptide 9 0.017
Cdk7 cyclin-dependent kinase 7 0.017
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.017
Eif4e eukaryotic translation initiation factor 4E 0.016
Mcm5 minichromosome maintenance complex component 5 0.016
Phf12 PHD finger protein 12 0.016
Mbtps1 membrane-bound transcription factor peptidase, site 1 0.016
Mki67 antigen identified by monoclonal antibody Ki-67 0.016
Cdk4 cyclin-dependent kinase 4 0.016
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.016
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.015
Tcf4 transcription factor 4 0.015
Lzts2 leucine zipper, putative tumor suppressor 2 0.015
Hist1h1a histone cluster 1, H1a 0.015
Dnah2 dynein, axonemal, heavy chain 2 0.015
Cbfb core-binding factor, beta subunit 0.015
Mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.015
Igf2r insulin-like growth factor 2 receptor 0.015
Il18 interleukin 18 0.015
Pth parathyroid hormone 0.015
Smad4 SMAD family member 4 0.015
Nfia nuclear factor I/A 0.014
Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 0.014
Cdca7 cell division cycle associated 7 0.014
Cdkn3 cyclin-dependent kinase inhibitor 3 0.014
Rln1 relaxin 1 0.014
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.014
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.014
Fermt2 fermitin family homolog 2 (Drosophila) 0.014
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.014
Fgf14 fibroblast growth factor 14 0.013
Trhr thyrotropin releasing hormone receptor 0.013
Hmgb2 high mobility group box 2 0.013
Vav1 vav 1 guanine nucleotide exchange factor 0.013
Arhgap1 Rho GTPase activating protein 1 0.013
LOC100360986 mCG1035404-like 0.013
Rgs19 regulator of G-protein signaling 19 0.013
Gabrb1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.013
Rgl2 ral guanine nucleotide dissociation stimulator-like 2 0.013