The network for 'cleavage involved in rrna processing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cleavage involved in rrna processing

Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RRP46 Rrp46p 0.999
RRP45 Rrp45p 0.992
CSL4 Csl4p 0.983
RRP40 Rrp40p 0.963
ENP1 Enp1p 0.957
NOP1 Nop1p 0.955
MTR3 Mtr3p 0.955
LRP1 Lrp1p 0.943
ECM16 Ecm16p 0.943
UTP10 Utp10p 0.929
SOF1 Sof1p 0.917
DIS3 Dis3p 0.896
RRP4 Rrp4p 0.887
MRD1 Mrd1p 0.884
PXR1 Pxr1p 0.878
BFR2 Bfr2p 0.850
KRR1 Krr1p 0.842
SKI6 Ski6p 0.822
FAF1 Faf1p 0.809
UTP13 Utp13p 0.797
MPP6 Mpp6p 0.735
SLX9 Slx9p 0.724
UTP18 Utp18p 0.704
ESF2 Esf2p 0.696
RIO1 Rio1p 0.685
RRP42 Rrp42p 0.683
UTP20 Utp20p 0.678
ENP2 Enp2p 0.671
NOP14 Nop14p 0.666
UBP10 Ubp10p 0.655
NOP6 Nop6p 0.642
NOP8 Nop8p 0.637
TRM112 Trm112p 0.628
IMP3 Imp3p 0.600
UTP8 Utp8p 0.593
RRP14 Rrp14p 0.584
UTP11 Utp11p 0.575
ESF1 Esf1p 0.575
UTP25 Utp25p 0.545
NOC4 Noc4p 0.535
NOP12 Nop12p 0.525
FUN12 Fun12p 0.517
RPF1 Rpf1p 0.494
NAN1 Nan1p 0.492
RRP43 Rrp43p 0.474
DIP2 Dip2p 0.453
PRP43 Prp43p 0.428
CBF5 Cbf5p 0.407
IMP4 Imp4p 0.384
UTP23 Utp23p 0.381
RPS17A Rps17ap 0.358
NAF1 Naf1p 0.352
GAR1 Gar1p 0.344
MPP10 Mpp10p 0.341
KRE33 Kre33p 0.330
RRP9 Rrp9p 0.327
RRP7 Rrp7p 0.321
SKI7 Ski7p 0.317
PWP2 Pwp2p 0.316
RRP5 Rrp5p 0.308
RPS21A Rps21ap 0.292
HMT1 Hmt1p 0.281
NOP56 Nop56p 0.279
PNO1 Pno1p 0.275
EBP2 Ebp2p 0.264
RRP12 Rrp12p 0.259
NOP10 Nop10p 0.254
UTP22 Utp22p 0.253
SAS10 Sas10p 0.245
BMS1 Bms1p 0.244
LCP5 Lcp5p 0.243
BUD21 Bud21p 0.221
UTP21 Utp21p 0.211
IMD2 Imd2p 0.211
UTP7 Utp7p 0.202
CWC24 Cwc24p 0.201
NOP2 Nop2p 0.195
SQT1 Sqt1p 0.191
RIO2 Rio2p 0.188
PAB1 Pab1p 0.172
NOP58 Nop58p 0.171
RRN3 Rrn3p 0.170
RRP6 Rrp6p 0.168
RRP36 Rrp36p 0.166
SEN15 Sen15p 0.166
DBP7 Dbp7p 0.163
FCF1 Fcf1p 0.148
UTP4 Utp4p 0.145
RPS11B Rps11bp 0.144
DHR2 Dhr2p 0.144
TMA23 Tma23p 0.137
CBR1 Cbr1p 0.127
DRS1 Drs1p 0.125
TSR1 Tsr1p 0.124
RPL22A Rpl22ap 0.123
AIR1 Air1p 0.123
DBP3 Dbp3p 0.116
NOB1 Nob1p 0.109
RBG1 Rbg1p 0.108
SNU13 Snu13p 0.108
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
CELE_C24H12.4 Protein C24H12.4 0.736
ZK430.7 Protein ZK430.7 0.686
W07E6.2 Protein W07E6.2 0.607
CELE_T04A8.6 Protein T04A8.6 0.572
pro-1 Protein PRO-1 0.515
acin-1 Protein ACIN-1 0.486
CELE_T06E6.1 Protein T06E6.1 0.470
CELE_F53F4.11 Protein F53F4.11 0.460
wdr-46 Protein WDR-46 0.430
dao-5 Protein DAO-5 0.400
elpc-3 Protein ELPC-3 0.395
tag-184 Protein TAG-184 0.373
F27C1.6 Protein F27C1.6 0.363
CELE_T26G10.1 Protein T26G10.1 0.355
C44E4.4 Protein C44E4.4 0.328
K07H8.10 Protein K07H8.10 0.328
C37H5.5 Protein C37H5.5 0.310
Y53C12B.1 Protein Y53C12B.1 0.269
prp-3 Protein PRP-3 0.254
suf-1 Protein SUF-1 0.236
K12H4.3 Protein K12H4.3 0.233
rbd-1 Protein RBD-1 0.232
nst-1 Protein NST-1 0.224
rrbs-1 Protein RRBS-1 0.219
F54C9.9 Protein F54C9.9 0.218
M28.5 Protein M28.5 0.202
tag-151 Protein TAG-151 0.194
W09C3.4 Protein W09C3.4 0.192
ZK1127.4 Protein ZK1127.4 0.181
dbr-1 Protein DBR-1 0.174
F09F7.3 Protein F09F7.3 0.172
CELE_Y48B6A.1 Protein Y48B6A.1 0.155
Y66H1A.4 Protein Y66H1A.4 0.153
CELE_ZK795.3 Protein ZK795.3 0.150
ZK418.9 Protein ZK418.9 0.137
rha-2 Protein RHA-2 0.133
F10E9.4 Protein F10E9.4 0.127
nol-5 Protein NOL-5 0.126
toe-1 Protein TOE-1 0.118
C47E12.7 Protein C47E12.7 0.113
trm-1 Protein TRM-1 0.106
ZK792.5 Protein ZK792.5 0.105
exos-9 Protein EXOS-9 0.102
F55F8.2 Protein F55F8.2 0.099
dnj-17 Protein DNJ-17 0.099
Y45F10D.7 Protein Y45F10D.7 0.097
dnj-19 Protein DNJ-19 0.093
tag-124 Protein TAG-124 0.093
CELE_C16C10.2 Protein C16C10.2 0.091
ngp-1 Protein NGP-1 0.090
W04C9.4 Protein W04C9.4 0.085
tut-1 Protein TUT-1 0.081
C05C8.2 Protein C05C8.2 0.079
C53H9.2 Protein C53H9.2 0.077
ZK512.2 Protein ZK512.2 0.077
K07C5.4 Protein K07C5.4 0.076
K04C2.2 Protein K04C2.2 0.076
CELE_C23G10.8 Protein C23G10.8 0.075
ZK546.14 Protein ZK546.14 0.075
Y37E11B.5 Protein Y37E11B.5 0.071
T20B12.3 Protein T20B12.3 0.069
C27F2.4 Protein C27F2.4 0.069
Y49F6B.2 Protein Y49F6B.2 0.067
Y110A7A.19 Protein Y110A7A.19 0.067
F49D11.10 Protein F49D11.10 0.065
K01G5.5 Protein K01G5.5 0.064
T11G6.8 Protein T11G6.8 0.063
fust-1 Protein FUST-1 0.061
E02H1.1 Protein E02H1.1 0.061
Y54E10A.10 Protein Y54E10A.10 0.060
fcp-1 Protein FCP-1 0.060
F25B5.5 Protein F25B5.5 0.059
T12E12.3 Protein T12E12.3 0.056
F53E10.6 Protein F53E10.6 0.053
R02F2.7 Protein R02F2.7 0.051
nol-1 Protein NOL-1 0.050
cir-1 Protein CIR-1 0.049
mrps-18C Protein MRPS-18C 0.049
T10B5.3 Protein T10B5.3 0.047
CELE_W03F9.10 Protein W03F9.10 0.046
pro-2 Protein PRO-2 0.044
F45F2.11 Protein F45F2.11 0.044
nath-10 Protein NATH-10 0.042
CELE_W02A11.1 Protein W02A11.1 0.042
C18A3.3 Protein C18A3.3 0.041
CELE_F07E5.5 Protein F07E5.5 0.041
Y46E12BL.2 Protein Y46E12BL.2 0.040
ZK686.2 Protein ZK686.2 0.040
CELE_Y41D4B.11 Protein Y41D4B.11 0.039
riok-1 Protein RIOK-1 0.038
spt-5 Protein SPT-5 0.038
rnp-3 Protein RNP-3 0.037
cdc-48.3 Protein CDC-48.3 0.037
puf-12 Protein PUF-12 0.037
F11A10.7 Protein F11A10.7 0.037
eif-3.E Protein EIF-3.E 0.037
F37A4.2 Protein F37A4.2 0.037
prp-21 Protein PRP-21 0.036
R186.7 Protein R186.7 0.034
thoc-2 Protein THOC-2 0.033
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Wdr43 WD repeat domain 43 0.649
Mybbp1a MYB binding protein (P160) 1a 0.636
Ppan peter pan homolog (Drosophila) 0.471
Ddx21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 0.463
Gnl3 guanine nucleotide binding protein-like 3 (nucleolar) 0.420
Rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.401
Nop2 NOP2 nucleolar protein homolog (yeast) 0.384
Utp20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.330
Smyd5 SET and MYND domain containing 5 0.279
Grwd1 glutamate-rich WD repeat containing 1 0.269
Pprc1 peroxisome proliferative activated receptor, gamma, coactivator-related 1 0.256
Ftsj3 FtsJ homolog 3 (E. coli) 0.220
Rrp15 ribosomal RNA processing 15 homolog (S. cerevisiae) 0.201
Nop56 NOP56 ribonucleoprotein homolog (yeast) 0.194
Ddx10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.164
Mettl1 methyltransferase like 1 0.156
Ccdc86 coiled-coil domain containing 86 0.147
D19Bwg1357e DNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed 0.126
Srm spermidine synthase 0.122
Rrp1b ribosomal RNA processing 1 homolog B (S. cerevisiae) 0.112
Heatr1 HEAT repeat containing 1 0.109
Tsr1 TSR1, 20S rRNA accumulation, homolog (yeast) 0.102
Nsun2 NOL1/NOP2/Sun domain family member 2 0.099
Wdr74 WD repeat domain 74 0.093
Rrp9 RRP9, small subunit (SSU) processome component, homolog (yeast) 0.093
Nolc1 nucleolar and coiled-body phosphoprotein 1 0.090
Atad3a ATPase family, AAA domain containing 3A 0.070
Fam203a family with sequence similarity 203, member A 0.067
Tars threonyl-tRNA synthetase 0.058
Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 0.057
Polr1b polymerase (RNA) I polypeptide B 0.056
Dkc1 dyskeratosis congenita 1, dyskerin homolog (human) 0.055
Pus1 pseudouridine synthase 1 0.053
Wdr75 WD repeat domain 75 0.052
Nop14 NOP14 nucleolar protein homolog (yeast) 0.050
Dis3 DIS3 mitotic control homolog (S. cerevisiae) 0.046
Spata5 spermatogenesis associated 5 0.046
Cpsf2 cleavage and polyadenylation specific factor 2 0.044
Mki67ip Mki67 (FHA domain) interacting nucleolar phosphoprotein 0.043
Prpf3 PRP3 pre-mRNA processing factor 3 homolog (yeast) 0.042
Sf3b3 splicing factor 3b, subunit 3 0.042
Pwp2 PWP2 periodic tryptophan protein homolog (yeast) 0.042
Gtpbp4 GTP binding protein 4 0.041
Ddx20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 0.040
Ltv1 LTV1 homolog (S. cerevisiae) 0.040
Ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.039
Wdr46 WD repeat domain 46 0.038
Ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.038
Dhx15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 0.037
Nubp1 nucleotide binding protein 1 0.037
Elac2 elaC homolog 2 (E. coli) 0.036
Brix1 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) 0.036
Rrs1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.034
Lrrc40 leucine rich repeat containing 40 0.033
Cebpz CCAAT/enhancer binding protein zeta 0.033
Aatf apoptosis antagonizing transcription factor 0.033
Sdad1 SDA1 domain containing 1 0.032
Nufip1 nuclear fragile X mental retardation protein interacting protein 1 0.030
Myc myelocytomatosis oncogene 0.030
Fbl fibrillarin 0.029
Noc3l nucleolar complex associated 3 homolog (S. cerevisiae) 0.029
Eif1a eukaryotic translation initiation factor 1A 0.029
Gpatch4 G patch domain containing 4 0.029
Gar1 GAR1 ribonucleoprotein homolog (yeast) 0.029
Tex10 testis expressed gene 10 0.027
Haus6 HAUS augmin-like complex, subunit 6 0.027
Pa2g4 proliferation-associated 2G4 0.026
Pus7l pseudouridylate synthase 7 homolog (S. cerevisiae)-like 0.026
U2af1 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 0.026
Nop16 NOP16 nucleolar protein homolog (yeast) 0.025
Polr1a polymerase (RNA) I polypeptide A 0.025
Zfp259 zinc finger protein 259 0.024
Nip7 nuclear import 7 homolog (S. cerevisiae) 0.023
Eed embryonic ectoderm development 0.023
2610027L16Rik RIKEN cDNA 2610027L16 gene 0.023
Msh6 mutS homolog 6 (E. coli) 0.022
Xpo5 exportin 5 0.022
Polr3a polymerase (RNA) III (DNA directed) polypeptide A 0.021
Ino80e INO80 complex subunit E 0.021
Ccar1 cell division cycle and apoptosis regulator 1 0.021
Utp15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast) 0.021
Cirh1a cirrhosis, autosomal recessive 1A (human) 0.020
Trp53 transformation related protein 53 0.020
Imp4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) 0.020
Dph2 DPH2 homolog (S. cerevisiae) 0.019
Rbm34 RNA binding motif protein 34 0.019
Vars valyl-tRNA synthetase 0.019
Twistnb TWIST neighbor 0.019
Ints5 integrator complex subunit 5 0.019
Mak16 MAK16 homolog (S. cerevisiae) 0.018
Larp7 La ribonucleoprotein domain family, member 7 0.018
Tbrg4 transforming growth factor beta regulated gene 4 0.018
Ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.018
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.017
Wdr55 WD repeat domain 55 0.017
Nol8 nucleolar protein 8 0.017
Pdcd11 programmed cell death 11 0.017
Ddx51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 0.017
Exosc10 exosome component 10 0.017
Ifrd2 interferon-related developmental regulator 2 0.017
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Rattus norvegicus
Name Description Probability Func Analog Organism