The network for 'negative regulation of mitotic cell cycle phase transition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of mitotic cell cycle phase transition

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GLC7 Glc7p 0.997
CDC55 Cdc55p 0.888
KEL1 Kel1p 0.805
RAD53 Rad53p 0.707
RPO26 Rpo26p 0.610
BUB3 Bub3p 0.597
PPH22 Pph22p 0.584
GIC1 Gic1p 0.502
PPH21 Pph21p 0.496
HHT1 Hht1p 0.491
SLK19 Slk19p 0.427
MAD2 Mad2p 0.362
SPT16 Spt16p 0.358
PSR2 Psr2p 0.350
RPB10 Rpb10p 0.349
RTS1 Rts1p 0.345
GBP2 Gbp2p 0.339
SIC1 Sic1p 0.336
CDC14 Cdc14p 0.330
CTF4 Ctf4p 0.325
CDC28 Cdc28p 0.325
MCM4 Mcm4p 0.318
CLB5 Clb5p 0.312
CLB3 Clb3p 0.312
BMH1 Bmh1p 0.300
POL1 Pol1p 0.289
ZDS2 Zds2p 0.267
DBF4 Dbf4p 0.266
CDC20 Cdc20p 0.253
NOP6 Nop6p 0.231
MAD3 Mad3p 0.227
BFA1 Bfa1p 0.219
RAD27 Rad27p 0.217
KIN3 Kin3p 0.215
CKA1 Cka1p 0.206
DPB2 Dpb2p 0.200
RCO1 Rco1p 0.199
SCC2 Scc2p 0.197
KIN1 Kin1p 0.194
BUB1 Bub1p 0.192
CLB4 Clb4p 0.187
NUD1 Nud1p 0.186
RAD9 Rad9p 0.180
CDC25 Cdc25p 0.180
TFG1 Tfg1p 0.177
CTF18 Ctf18p 0.173
MCM6 Mcm6p 0.172
MCM10 Mcm10p 0.169
PSR1 Psr1p 0.169
CTF13 Ctf13p 0.167
IML3 Iml3p 0.158
SMC3 Smc3p 0.158
DMA2 Dma2p 0.155
RAD54 Rad54p 0.150
CHL1 Chl1p 0.139
CDC6 Cdc6p 0.138
BCK1 Bck1p 0.135
CHL4 Chl4p 0.135
RRM3 Rrm3p 0.133
LTE1 Lte1p 0.133
MCM2 Mcm2p 0.131
RAD52 Rad52p 0.131
ASE1 Ase1p 0.129
ASF1 Asf1p 0.128
POL30 Pol30p 0.123
PIG2 Pig2p 0.116
EAF1 Eaf1p 0.112
GSY1 Gsy1p 0.111
MCM21 Mcm21p 0.109
CLB6 Clb6p 0.108
GSY2 Gsy2p 0.108
CLN3 Cln3p 0.104
SET1 Set1p 0.103
PDS1 Pds1p 0.102
ZDS1 Zds1p 0.102
GIN4 Gin4p 0.099
PPZ1 Ppz1p 0.098
SAT4 Sat4p 0.094
SWI1 Swi1p 0.093
RTT107 Rtt107p 0.092
PPH3 Pph3p 0.092
RAD50 Rad50p 0.091
MNN9 Mnn9p 0.089
RFA1 Rfa1p 0.089
SWI3 Swi3p 0.088
RAD24 Rad24p 0.087
TIP41 Tip41p 0.086
DEF1 Def1p 0.085
SRS2 Srs2p 0.085
DAM1 Dam1p 0.082
BIM1 Bim1p 0.080
BEM3 Bem3p 0.080
NBL1 Nbl1p 0.079
DSN1 Dsn1p 0.079
CKS1 Cks1p 0.078
CLB1 Clb1p 0.078
RIF1 Rif1p 0.077
CDC45 Cdc45p 0.077
CSE4 Cse4p 0.076
TOF2 Tof2p 0.075
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
csn-3 Protein CSN-3 0.129
hpo-9 Protein HPO-9 0.077
mat-3 Protein MAT-3 0.073
npp-21 Protein NPP-21 0.062
brc-1 Protein BRC-1 0.058
hcf-1 Protein HCF-1 0.058
set-1 Protein SET-1 0.057
his-6 Protein HIS-6 0.047
lin-9 Protein LIN-9 0.044
C10G11.7 Protein C10G11.7 0.044
rnr-1 Protein RNR-1 0.043
ran-1 Protein RAN-1 0.032
klp-19 Protein KLP-19 0.030
dsh-2 Protein DSH-2 0.029
zyg-9 Protein ZYG-9 0.029
emb-5 Protein EMB-5 0.026
mex-5 Protein MEX-5 0.025
asd-1 Protein ASD-1 0.024
rsp-1 Protein RSP-1 0.024
panl-2 Protein PANL-2 0.024
hcp-1 Protein HCP-1 0.023
lag-1 Protein LAG-1 0.020
sqv-4 Protein SQV-4 0.020
rod-1 Protein ROD-1 0.020
D1081.8 Protein D1081.8 0.019
T19H12.2 Protein T19H12.2 0.018
R05D11.9 Protein R05D11.9 0.017
eya-1 Protein EYA-1 0.016
knl-1 Protein KNL-1 0.016
isw-1 Protein ISW-1 0.015
mcm-3 Protein MCM-3 0.015
lin-15B Protein LIN-15B 0.015
ZK507.6 Protein ZK507.6 0.015
atg-18 Protein ATG-18 0.015
gly-20 Protein GLY-20 0.015
B0464.6 Protein B0464.6 0.014
lig-1 Protein LIG-1 0.014
rsp-8 Protein RSP-8 0.014
fox-1 Protein FOX-1 0.014
csn-1 Protein CSN-1 0.014
npp-15 Protein NPP-15 0.013
him-1 Protein HIM-1 0.013
spd-5 Protein SPD-5 0.013
npp-7 Protein NPP-7 0.013
hcp-6 Protein HCP-6 0.013
daf-2 Protein DAF-2 0.013
T05E8.3 Protein T05E8.3 0.013
egg-6 Protein EGG-6 0.013
CELE_C24H12.5 Protein C24H12.5 0.012
hsr-9 Protein HSR-9 0.012
aipl-1 Protein AIPL-1 0.012
npp-16 Protein NPP-16 0.012
pabp-2 Protein PABP-2 0.012
plk-1 Protein PLK-1 0.011
F12F6.1 Protein F12F6.1 0.011
lin-8 Protein LIN-8 0.011
cep-1 Protein CEP-1 0.011
pri-2 Protein PRI-2 0.011
rla-0 Protein RLA-0 0.011
T22C1.1 Protein T22C1.1 0.011
his-42 Protein HIS-42 0.011
hpo-10 Protein HPO-10 0.011
xpo-1 Protein XPO-1 0.010
swsn-7 Protein SWSN-7 0.010
npp-11 Protein NPP-11 0.010
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Danio rerio
Name Description Probability Func Analog Organism
ccnd1 cyclin D1 0.305
plk1 polo-like kinase 1 (Drosophila) 0.147
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.090
kif23 kinesin family member 23 0.062
smc4 structural maintenance of chromosomes 4 0.061
rpl23 ribosomal protein L23 0.060
ccnb2 cyclin B2 0.059
ccna2 cyclin A2 0.058
ccnb1 cyclin B1 0.057
si:ch211-244o22.2 si:ch211-244o22.2 0.045
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.045
ube2i2 ubiquitin-conjugating enzyme E2I2 0.043
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.042
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.041
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.041
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.040
rfc4 replication factor C (activator 1) 4 0.038
aurkb aurora kinase B 0.037
caprin1a cell cycle associated protein 1a 0.036
zff9 zinc finger protein 9 0.036
tgif1 TGFB-induced factor homeobox 1 0.034
pcna proliferating cell nuclear antigen 0.034
ddb2 damage-specific DNA binding protein 2 0.032
atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.026
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.025
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.025
rasl11b RAS-like, family 11, member B 0.024
smc3 structural maintenance of chromosomes 3 0.024
rpa3 replication protein A3 0.024
skp2 S-phase kinase-associated protein 2 (p45) 0.023
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.022
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.022
hdac3 histone deacetylase 3 0.022
rbpms2 RNA binding protein with multiple splicing 2 0.021
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.021
snrpd1 small nuclear ribonucleoprotein D1 polypeptide 0.021
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.019
srsf1a serine/arginine-rich splicing factor 1a 0.018
tp53 tumor protein p53 0.018
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.017
eif2d eukaryotic translation initiation factor 2D 0.017
mapk3 mitogen-activated protein kinase 3 0.016
ncapg non-SMC condensin I complex, subunit G 0.016
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.016
zgc:153910 zgc:153910 0.016
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.016
tipin timeless interacting protein 0.015
dusp1 dual specificity phosphatase 1 0.015
sox11a SRY-box containing gene 11a 0.015
brd2a bromodomain-containing 2a 0.014
pak2b p21 (CDKN1A)-activated kinase 2b 0.014
hnrpl heterogeneous nuclear ribonucleoprotein L 0.014
crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.014
cand1 cullin-associated and neddylation-dissociated 1 0.013
rhoab ras homolog gene family, member Ab 0.013
nutf2l nuclear transport factor 2, like 0.013
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.013
si:ch211-69g19.2 si:ch211-69g19.2 0.012
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.012
gmnn geminin, DNA replication inhibitor 0.012
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.012
fabp7a fatty acid binding protein 7, brain, a 0.011
ppp2r5eb protein phosphatase 2, regulatory subunit B', epsilon isoform b 0.011
abcf1 ATP-binding cassette, sub-family F (GCN20), member 1 0.011
fen1 flap structure-specific endonuclease 1 0.011
dtl denticleless homolog (Drosophila) 0.011
naa15b N(alpha)-acetyltransferase 15, NatA auxiliary subunit b 0.011
ccne cyclin E 0.011
msh6 mutS homolog 6 (E. coli) 0.011
tfam transcription factor A, mitochondrial 0.011
cdc42 cell division cycle 42 0.011
ptp4a3 protein tyrosine phosphatase type IVA, member 3 0.011
smarcb1a SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a 0.011
cul3a cullin 3a 0.010
usp4 ubiquitin specific protease 4 (proto-oncogene) 0.010
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.010
lpl lipoprotein lipase 0.010
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Iswi Imitation SWI 0.989
Dref DNA replication-related element factor 0.984
lok loki 0.972
tefu telomere fusion 0.961
Ras85D Ras oncogene at 85D 0.872
pie pineapple eye 0.835
Rpd3 CG7471 gene product from transcript CG7471-RA 0.786
p53 CG33336 gene product from transcript CG33336-RB 0.771
Akt1 CG4006 gene product from transcript CG4006-RA 0.760
thr three rows 0.754
Rca1 Regulator of cyclin A1 0.749
skpA CG16983 gene product from transcript CG16983-RD 0.740
CDC45L CG3658 gene product from transcript CG3658-RA 0.726
mus304 mutagen-sensitive 304 0.654
CycB3 Cyclin B3 0.638
Snr1 Snf5-related 1 0.625
Rcd1 Reduction in Cnn dots 1 0.619
swm second mitotic wave missing 0.610
rux roughex 0.582
phl pole hole 0.581
Cdc37 CG12019 gene product from transcript CG12019-RA 0.579
BRWD3 CG31132 gene product from transcript CG31132-RA 0.578
BubR1 Bub1-related kinase 0.570
asp abnormal spindle 0.570
Brca2 Breast cancer 2, early onset homolog 0.563
CSN3 COP9 complex homolog subunit 3 0.551
Fcp1 CG12252 gene product from transcript CG12252-RA 0.551
cdm cadmus 0.502
E2f2 E2F transcription factor 2 0.501
Spc105R Spc105-related 0.499
Caf1 Chromatin assembly factor 1 subunit 0.498
dre4 CG1828 gene product from transcript CG1828-RB 0.492
CSN5 COP9 complex homolog subunit 5 0.487
RPA2 Replication protein A2 0.486
RanGap Ran GTPase activating protein 0.486
cdc2c CG10498 gene product from transcript CG10498-RC 0.482
poly CG9829 gene product from transcript CG9829-RB 0.466
MED6 Mediator complex subunit 6 0.461
mus205 mutagen-sensitive 205 0.454
cdc2 CG5363 gene product from transcript CG5363-RA 0.454
wee CG4488 gene product from transcript CG4488-RA 0.451
CycD Cyclin D 0.448
east enhanced adult sensory threshold 0.446
mus312 mutagen-sensitive 312 0.437
rad50 CG6339 gene product from transcript CG6339-RD 0.431
CycB Cyclin B 0.426
Klp3A Kinesin-like protein at 3A 0.418
ago archipelago 0.414
Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein 0.408
ssp sunspot 0.404
lwr lesswright 0.404
Bj1 Bj1 protein 0.397
Smox Smad on X 0.397
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.389
cal1 chromosome alignment defect 1 0.369
Art1 Arginine methyltransferase 1 0.356
Dlic Dynein light intermediate chain 0.340
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.320
CSN7 COP9 complex homolog subunit 7 0.320
not non-stop 0.319
ncd non-claret disjunctional 0.316
wapl wings apart-like 0.314
Cap-G CG34438 gene product from transcript CG34438-RF 0.314
Bap55 Brahma associated protein 55kD 0.310
Nup50 Nucleoporin 50 0.307
DNApol-alpha180 DNA polymerase alpha 180kD 0.306
gro groucho 0.303
MED31 Mediator complex subunit 31 0.303
fzy fizzy 0.293
kto kohtalo 0.291
U2af50 U2 small nuclear riboprotein auxiliary factor 50 0.291
rept reptin 0.285
Dhod Dihydroorotate dehydrogenase 0.282
SAK Sak kinase 0.275
MED17 Mediator complex subunit 17 0.272
emb embargoed 0.270
DNApol-alpha60 DNA polymerase alpha 60kD 0.269
Rbf Retinoblastoma-family protein 0.268
Nup214 Nucleoporin 214 0.267
CstF-64 Cleavage stimulation factor 64 kilodalton subunit 0.264
plu plutonium 0.262
pic piccolo 0.262
cnn centrosomin 0.259
CycK Cyclin K 0.258
gek genghis khan 0.254
Rcd5 Reduction in Cnn dots 5 0.251
babo baboon 0.251
His2Av Histone H2A variant 0.243
imd immune deficiency 0.242
CSN4 COP9 complex homolog subunit 4 0.235
ttv tout-velu 0.233
spn-E spindle E 0.230
mad2 CG17498 gene product from transcript CG17498-RA 0.230
heph hephaestus 0.230
Rel Relish 0.229
CG14641 CG14641 gene product from transcript CG14641-RA 0.227
Pp1-87B Protein phosphatase 1 at 87B 0.224
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.224
crp cropped 0.222
cutlet CG33122 gene product from transcript CG33122-RA 0.221
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
BRCA1 breast cancer 1, early onset 0.998
CDK2 cyclin-dependent kinase 2 0.995
RB1 retinoblastoma 1 0.995
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.992
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.988
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.984
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.969
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.945
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.932
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.895
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.890
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.885
RBL2 retinoblastoma-like 2 (p130) 0.883
CCNB1 cyclin B1 0.874
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.870
CCNA2 cyclin A2 0.846
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.837
ATM ataxia telangiectasia mutated 0.805
CCND1 cyclin D1 0.773
MSH6 mutS homolog 6 (E. coli) 0.757
RAD50 RAD50 homolog (S. cerevisiae) 0.726
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.722
RPA1 replication protein A1, 70kDa 0.696
E2F1 E2F transcription factor 1 0.690
RBL1 retinoblastoma-like 1 (p107) 0.670
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.670
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.668
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.656
PARP1 poly (ADP-ribose) polymerase 1 0.649
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.646
TOPBP1 topoisomerase (DNA) II binding protein 1 0.638
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.605
CUL4A cullin 4A 0.601
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.577
SMAD7 SMAD family member 7 0.567
OTUB1 OTU domain, ubiquitin aldehyde binding 1 0.563
BCL2 B-cell CLL/lymphoma 2 0.559
PCNA proliferating cell nuclear antigen 0.556
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.545
HDAC2 histone deacetylase 2 0.525
CDK8 cyclin-dependent kinase 8 0.521
WRN Werner syndrome, RecQ helicase-like 0.519
WWOX WW domain containing oxidoreductase 0.518
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.508
XIAP X-linked inhibitor of apoptosis 0.496
COPS4 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) 0.489
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) 0.486
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.484
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.483
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.482
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.475
FADD Fas (TNFRSF6)-associated via death domain 0.469
IRAK2 interleukin-1 receptor-associated kinase 2 0.457
COPS8 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) 0.436
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.436
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.436
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.434
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.431
JUN jun proto-oncogene 0.403
CCNE1 cyclin E1 0.402
MDC1 mediator of DNA-damage checkpoint 1 0.400
RBBP8 retinoblastoma binding protein 8 0.398
CLSPN claspin 0.391
TFDP1 transcription factor Dp-1 0.389
SKP2 S-phase kinase-associated protein 2 (p45) 0.386
CUL2 cullin 2 0.385
ANAPC4 anaphase promoting complex subunit 4 0.358
TOP1 topoisomerase (DNA) I 0.352
ANAPC5 anaphase promoting complex subunit 5 0.326
ARID1A AT rich interactive domain 1A (SWI-like) 0.323
CDC25A cell division cycle 25 homolog A (S. pombe) 0.320
RAD9A RAD9 homolog A (S. pombe) 0.314
CREBBP CREB binding protein 0.311
UBE3A ubiquitin protein ligase E3A 0.311
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.309
WDR5 WD repeat domain 5 0.308
PLK1 polo-like kinase 1 0.289
PBK PDZ binding kinase 0.288
E2F8 E2F transcription factor 8 0.286
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.279
TP53BP1 tumor protein p53 binding protein 1 0.279
TOP2A topoisomerase (DNA) II alpha 170kDa 0.277
RAD1 RAD1 homolog (S. pombe) 0.272
CBX5 chromobox homolog 5 0.267
MED1 mediator complex subunit 1 0.264
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.263
CDK6 cyclin-dependent kinase 6 0.260
CCND3 cyclin D3 0.254
UBA1 ubiquitin-like modifier activating enzyme 1 0.252
SFN stratifin 0.250
CHD4 chromodomain helicase DNA binding protein 4 0.247
KAT2B K(lysine) acetyltransferase 2B 0.245
EGFR epidermal growth factor receptor 0.245
AURKB aurora kinase B 0.243
COPS6 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) 0.243
MED29 mediator complex subunit 29 0.237
UBXN7 UBX domain protein 7 0.235
SMC4 structural maintenance of chromosomes 4 0.234
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.233
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Rb1 retinoblastoma 1 0.991
Brca1 breast cancer 1 0.974
Brca2 breast cancer 2 0.917
Cdk4 cyclin-dependent kinase 4 0.899
Pten phosphatase and tensin homolog 0.895
E2f1 E2F transcription factor 1 0.850
Mdm2 transformed mouse 3T3 cell double minute 2 0.797
Rpgrip1l Rpgrip1-like 0.724
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.694
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.691
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.682
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.677
Bax BCL2-associated X protein 0.673
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.659
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.658
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.653
Atm ataxia telangiectasia mutated homolog (human) 0.599
Arid1b AT rich interactive domain 1B (SWI-like) 0.589
Mdm4 transformed mouse 3T3 cell double minute 4 0.540
Dna2 DNA replication helicase 2 homolog (yeast) 0.520
Cdk2 cyclin-dependent kinase 2 0.471
Smad4 MAD homolog 4 (Drosophila) 0.451
Nbn nibrin 0.436
Hells helicase, lymphoid specific 0.429
Prc1 protein regulator of cytokinesis 1 0.423
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.421
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.417
Nf1 neurofibromatosis 1 0.397
Ctnnb1 catenin (cadherin associated protein), beta 1 0.372
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.354
Tcf3 transcription factor 3 0.348
Setdb1 SET domain, bifurcated 1 0.348
Kit kit oncogene 0.326
Rbl1 retinoblastoma-like 1 (p107) 0.321
Apc adenomatosis polyposis coli 0.319
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.316
Shh sonic hedgehog 0.312
Cdk1 cyclin-dependent kinase 1 0.310
Ccna2 cyclin A2 0.302
Rnf2 ring finger protein 2 0.302
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.293
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.288
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.275
Trp63 transformation related protein 63 0.269
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.267
Kif23 kinesin family member 23 0.255
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.250
Cdca5 cell division cycle associated 5 0.245
Msh2 mutS homolog 2 (E. coli) 0.237
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.226
Plk4 polo-like kinase 4 (Drosophila) 0.225
Cd80 CD80 antigen 0.208
Ptch1 patched homolog 1 0.204
Mis18bp1 MIS18 binding protein 1 0.204
Ccnf cyclin F 0.201
Aurka aurora kinase A 0.201
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.199
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.193
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.185
Ckap2 cytoskeleton associated protein 2 0.183
Bcl2 B-cell leukemia/lymphoma 2 0.181
Notch1 Notch gene homolog 1 (Drosophila) 0.170
Ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.167
Rara retinoic acid receptor, alpha 0.163
Cdca8 cell division cycle associated 8 0.159
Rad51ap1 RAD51 associated protein 1 0.159
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.157
Rbl2 retinoblastoma-like 2 0.144
Kdm2b lysine (K)-specific demethylase 2B 0.143
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.140
Kif4 kinesin family member 4 0.136
Dtl denticleless homolog (Drosophila) 0.135
Blm Bloom syndrome, RecQ helicase-like 0.132
Cenpk centromere protein K 0.131
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.131
Plk1 polo-like kinase 1 (Drosophila) 0.129
Pou5f1 POU domain, class 5, transcription factor 1 0.129
Tmpo thymopoietin 0.127
Gpi1 glucose phosphate isomerase 1 0.119
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.118
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.117
Fen1 flap structure specific endonuclease 1 0.115
Mybl2 myeloblastosis oncogene-like 2 0.113
Bak1 BCL2-antagonist/killer 1 0.113
Gja1 gap junction protein, alpha 1 0.113
Aurkb aurora kinase B 0.112
Ret ret proto-oncogene 0.112
Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.111
Orc1 origin recognition complex, subunit 1 0.111
Bub1 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) 0.106
Ccnb2 cyclin B2 0.105
Raf1 v-raf-leukemia viral oncogene 1 0.104
Cbl Casitas B-lineage lymphoma 0.104
Gtse1 G two S phase expressed protein 1 0.103
Bmi1 Bmi1 polycomb ring finger oncogene 0.103
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.102
Exo1 exonuclease 1 0.101
Kif2c kinesin family member 2C 0.101
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.099
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Rattus norvegicus
Name Description Probability Func Analog Organism
Top2a topoisomerase (DNA) II alpha 0.152
Pkm2 pyruvate kinase, muscle 0.111
Kifc1 kinesin family member C1 0.101
Racgap1 Rac GTPase-activating protein 1 0.092
Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.074
Usp9x ubiquitin specific peptidase 9, X-linked 0.056
Tcp11l2 t-complex 11 (mouse) like 2 0.055
Mdm2 Mdm2 p53 binding protein homolog (mouse) 0.055
Kif22 kinesin family member 22 0.053
Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) 0.051
Slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.051
Cdk4 cyclin-dependent kinase 4 0.046
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.046
Top2b topoisomerase (DNA) II beta 0.045
Cdk2 cyclin dependent kinase 2 0.045
March8 membrane-associated ring finger (C3HC4) 8 0.045
Aurkb aurora kinase B 0.045
Gpi glucose phosphate isomerase 0.045
Rbbp7 retinoblastoma binding protein 7 0.044
Cdk1 cyclin-dependent kinase 1 0.042
Mcm7 minichromosome maintenance complex component 7 0.041
Tpi1 triosephosphate isomerase 1 0.040
Pcyox1 prenylcysteine oxidase 1 0.039
Ccnd3 cyclin D3 0.039
Gtf2i general transcription factor II I 0.038
Pctk1 PCTAIRE protein kinase 1 0.037
Ccnb1 cyclin B1 0.037
Dhfr dihydrofolate reductase 0.036
Ccnb2 cyclin B2 0.036
Rpa2 replication protein A2 0.036
Serinc1 serine incorporator 1 0.035
Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.035
Mcm6 minichromosome maintenance complex component 6 0.035
Rabep1 rabaptin, RAB GTPase binding effector protein 1 0.035
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.035
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.035
Rara retinoic acid receptor, alpha 0.034
Kif2c kinesin family member 2C 0.034
Taok1 TAO kinase 1 0.033
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.033
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.033
Pbk PDZ binding kinase 0.032
Tob1 transducer of ErbB-2.1 0.032
Ptbp1 polypyrimidine tract binding protein 1 0.031
Zfand5 zinc finger, AN1-type domain 5 0.031
Stxbp3 syntaxin binding protein 3 0.031
Tcf12 transcription factor 12 0.031
Rrm2 ribonucleotide reductase M2 0.031
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.030
Rgs19 regulator of G-protein signaling 19 0.029
Ispd isoprenoid synthase domain containing 0.029
Hist1h1a histone cluster 1, H1a 0.029
Ect2 epithelial cell transforming sequence 2 oncogene 0.029
Homer1 homer homolog 1 (Drosophila) 0.028
S1pr2 sphingosine-1-phosphate receptor 2 0.028
Zhx1 zinc fingers and homeoboxes 1 0.028
Fen1 flap structure-specific endonuclease 1 0.028
Csnk2b casein kinase 2, beta polypeptide 0.028
Creb1 cAMP responsive element binding protein 1 0.027
Ubl3 ubiquitin-like 3 0.027
Rfc1 replication factor C (activator 1) 1 0.027
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.027
Daxx death-domain associated protein 0.027
Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.027
Cdca7 cell division cycle associated 7 0.027
Pttg1 pituitary tumor-transforming 1 0.026
Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 0.026
Nrd1 nardilysin 1 0.026
Cul3 cullin 3 0.026
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.025
Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 0.025
Necap2 NECAP endocytosis associated 2 0.025
Plk4 polo-like kinase 4 (Drosophila) 0.025
Erlec1 endoplasmic reticulum lectin 1 0.025
Prc1 protein regulator of cytokinesis 1 0.025
Sesn1 sestrin 1 0.024
Rad51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.024
Snrpa small nuclear ribonucleoprotein polypeptide A 0.024
Vdac3 voltage-dependent anion channel 3 0.024
Slc4a2 solute carrier family 4 (anion exchanger), member 2 0.024
Sh3yl1 SH3 domain containing, Ysc84-like 1 (S. cerevisiae) 0.024
Ubtf upstream binding transcription factor, RNA polymerase I 0.024
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.024
Sdc1 syndecan 1 0.024
Vegfa vascular endothelial growth factor A 0.023
Vapa VAMP (vesicle-associated membrane protein)-associated protein A 0.023
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.023
Spg20 spastic paraplegia 20 (Troyer syndrome) homolog (human) 0.023
Ccng2 cyclin G2 0.023
Hk1 hexokinase 1 0.023
Ndrg2 N-myc downstream regulated gene 2 0.023
Homer3 homer homolog 3 (Drosophila) 0.023
Dlg3 discs, large homolog 3 (Drosophila) 0.023
Mxi1 MAX interactor 1 0.023
Fam116a family with sequence similarity 116, member A 0.023
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.023
Arhgap11a Rho GTPase activating protein 11A 0.023
Mcf2l MCF.2 cell line derived transforming sequence-like 0.023
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.023
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.023