The network for 'regulation of rna polymerase ii transcriptional preinitiation complex assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of rna polymerase ii transcriptional preinitiation complex assembly

Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RPN1 Rpn1p 0.041
SPT5 Spt5p 0.035
RPN2 Rpn2p 0.035
RPT1 Rpt1p 0.024
RPT2 Rpt2p 0.023
RPT6 Rpt6p 0.022
TFG2 Tfg2p 0.021
TAF10 Taf10p 0.020
NGG1 Ngg1p 0.020
TRA1 Tra1p 0.020
BUR6 Bur6p 0.020
RPN9 Rpn9p 0.019
TFG1 Tfg1p 0.019
RPT5 Rpt5p 0.018
SEM1 Sem1p 0.017
RSC4 Rsc4p 0.016
RPT4 Rpt4p 0.016
TAF12 Taf12p 0.015
RPN7 Rpn7p 0.015
SPT8 Spt8p 0.014
CUP1-1 Cup1-1p 0.014
CKA1 Cka1p 0.013
RPT3 Rpt3p 0.013
RPN13 Rpn13p 0.013
CTR9 Ctr9p 0.013
SRD1 Srd1p 0.013
YLR264C-A hypothetical protein 0.013
WWM1 Wwm1p 0.013
LEU2 Leu2p 0.013
RAD23 Rad23p 0.012
TFA1 Tfa1p 0.012
YOL038C-A hypothetical protein 0.012
LEO1 Leo1p 0.012
YLR162W hypothetical protein 0.012
MER1 Mer1p 0.012
HXT3 Hxt3p 0.011
ARP10 Arp10p 0.011
TAF4 Taf4p 0.011
ARG8 Arg8p 0.011
YPR157W hypothetical protein 0.011
SPL2 Spl2p 0.011
URA3 Ura3p 0.011
ATP6 Atp6p 0.011
PRS2 Prs2p 0.011
RPO21 Rpo21p 0.010
HO Hop 0.010
YAR068W hypothetical protein 0.010
TAF6 Taf6p 0.010
CHA1 Cha1p 0.010
SWC7 Swc7p 0.010
YLR042C hypothetical protein 0.010
GYL1 Gyl1p 0.010
PUP1 Pup1p 0.010
RTF1 Rtf1p 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rpt4 CG3455 gene product from transcript CG3455-RA 0.700
CG13349 CG13349 gene product from transcript CG13349-RA 0.492
CG12321 CG12321 gene product from transcript CG12321-RA 0.292
Pros26.4 Proteasome 26S subunit subunit 4 ATPase 0.226
Rpn1 CG7762 gene product from transcript CG7762-RA 0.150
Rpn11 CG18174 gene product from transcript CG18174-RA 0.086
Rpn9 CG10230 gene product from transcript CG10230-RB 0.060
Pros45 CG1489 gene product from transcript CG1489-RA 0.052
Rpt1 CG1341 gene product from transcript CG1341-RA 0.051
Rpn7 CG5378 gene product from transcript CG5378-RA 0.044
Rpn6 Proteasome p44.5 subunit 0.038
Rpt3 CG16916 gene product from transcript CG16916-RA 0.036
Mov34 CG3416 gene product from transcript CG3416-RA 0.027
Rpn3 Regulatory particle non-ATPase 3 0.023
Tbp-1 Tat-binding protein-1 0.022
bab2 CG9102 gene product from transcript CG9102-RA 0.018
rn rotund 0.016
Ice CG7788 gene product from transcript CG7788-RA 0.015
CG5384 CG5384 gene product from transcript CG5384-RA 0.015
Prosalpha7 Proteasome alpha7 subunit 0.014
Prosbeta7 Proteasome beta7 subunit 0.014
Pros29 Proteasome 29kD subunit 0.012
Pros25 Proteasome 25kD subunit 0.012
fj four-jointed 0.011
dmt dalmatian 0.011
Dll Distal-less 0.011
lsn larsen 0.011
Rpn5 CG1100 gene product from transcript CG1100-RA 0.010
Rpn12 CG4157 gene product from transcript CG4157-RA 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.998
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.985
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.971
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.942
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.928
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.815
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.771
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.707
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.675
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.594
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.578
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.521
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.378
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.319
RXRA retinoid X receptor, alpha 0.290
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.159
SP1 Sp1 transcription factor 0.134
MED25 mediator complex subunit 25 0.097
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.066
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.058
HMGB1 high mobility group box 1 0.057
NCOA1 nuclear receptor coactivator 1 0.054
NCOA6 nuclear receptor coactivator 6 0.052
CSNK1A1 casein kinase 1, alpha 1 0.052
NCOR2 nuclear receptor corepressor 2 0.051
ARNT aryl hydrocarbon receptor nuclear translocator 0.050
PAAF1 proteasomal ATPase-associated factor 1 0.045
HMGA1 high mobility group AT-hook 1 0.044
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.039
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.035
RARA retinoic acid receptor, alpha 0.034
RB1 retinoblastoma 1 0.033
PTMA prothymosin, alpha 0.032
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.031
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.031
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.028
MED1 mediator complex subunit 1 0.027
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.026
SKIL SKI-like oncogene 0.025
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.024
NCOA3 nuclear receptor coactivator 3 0.024
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.023
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 0.023
MACF1 microtubule-actin crosslinking factor 1 0.023
ZNF518A zinc finger protein 518A 0.022
RAD21 RAD21 homolog (S. pombe) 0.021
MARK3 MAP/microtubule affinity-regulating kinase 3 0.021
SSRP1 structure specific recognition protein 1 0.021
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.019
EP300 E1A binding protein p300 0.019
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 0.018
NCOA7 nuclear receptor coactivator 7 0.017
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.017
HMGN2 high mobility group nucleosomal binding domain 2 0.017
HMGB2 high mobility group box 2 0.016
PPARA peroxisome proliferator-activated receptor alpha 0.016
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.016
MAPK14 mitogen-activated protein kinase 14 0.015
KAT2B K(lysine) acetyltransferase 2B 0.015
HMGN1 high mobility group nucleosome binding domain 1 0.014
RXRB retinoid X receptor, beta 0.013
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.013
NCOA2 nuclear receptor coactivator 2 0.013
MAGED2 melanoma antigen family D, 2 0.013
PRMT6 protein arginine methyltransferase 6 0.013
ZNF350 zinc finger protein 350 0.012
POU2F1 POU class 2 homeobox 1 0.012
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.012
HDGF hepatoma-derived growth factor 0.012
MAGEA11 melanoma antigen family A, 11 0.012
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.011
C5orf41 chromosome 5 open reading frame 41 0.011
FAM190B family with sequence similarity 190, member B 0.011
CADM1 cell adhesion molecule 1 0.011
ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) 0.011
CCNL1 cyclin L1 0.011
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.011
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.011
RBM25 RNA binding motif protein 25 0.011
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.010
SPIN1 spindlin 1 0.010
TRIM33 tripartite motif containing 33 0.010
CENPT centromere protein T 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Gli3 GLI-Kruppel family member GLI3 1.000
Pax2 paired box gene 2 0.999
Shh sonic hedgehog 0.997
Fgf8 fibroblast growth factor 8 0.995
Pax8 paired box gene 8 0.991
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.990
Fgfr2 fibroblast growth factor receptor 2 0.989
Wnt3a wingless-related MMTV integration site 3A 0.984
Sox9 SRY-box containing gene 9 0.971
Rarg retinoic acid receptor, gamma 0.967
Gli2 GLI-Kruppel family member GLI2 0.963
Tbx1 T-box 1 0.943
Fgfr1 fibroblast growth factor receptor 1 0.936
Lhx1 LIM homeobox protein 1 0.929
Foxc1 forkhead box C1 0.924
Gdnf glial cell line derived neurotrophic factor 0.923
Ctnnb1 catenin (cadherin associated protein), beta 1 0.899
Bmp7 bone morphogenetic protein 7 0.898
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.877
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.860
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.846
Rarb retinoic acid receptor, beta 0.830
T brachyury 0.804
Pten phosphatase and tensin homolog 0.780
Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.776
Wnt4 wingless-related MMTV integration site 4 0.769
Pax3 paired box gene 3 0.768
Smo smoothened homolog (Drosophila) 0.748
Lmx1a LIM homeobox transcription factor 1 alpha 0.728
Bmp4 bone morphogenetic protein 4 0.678
Prrx2 paired related homeobox 2 0.646
Hoxd13 homeobox D13 0.642
Otx1 orthodenticle homolog 1 (Drosophila) 0.637
Fgf10 fibroblast growth factor 10 0.637
Twist2 twist homolog 2 (Drosophila) 0.630
Hoxa2 homeobox A2 0.626
Col13a1 collagen, type XIII, alpha 1 0.614
Hoxd11 homeobox D11 0.613
Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.600
Fgfr3 fibroblast growth factor receptor 3 0.598
Pax1 paired box gene 1 0.576
Msx1 homeobox, msh-like 1 0.574
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.564
Emx2 empty spiracles homolog 2 (Drosophila) 0.558
Nog noggin 0.546
Trp63 transformation related protein 63 0.540
Ar androgen receptor 0.539
Dlx5 distal-less homeobox 5 0.534
Thrb thyroid hormone receptor beta 0.523
Pitx2 paired-like homeodomain transcription factor 2 0.519
Wnt10b wingless related MMTV integration site 10b 0.517
Wnt6 wingless-related MMTV integration site 6 0.514
Rara retinoic acid receptor, alpha 0.494
Foxn1 forkhead box N1 0.494
Rxra retinoid X receptor alpha 0.487
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.458
Ghr growth hormone receptor 0.451
Col2a1 collagen, type II, alpha 1 0.449
Fgf18 fibroblast growth factor 18 0.445
Otx2 orthodenticle homolog 2 (Drosophila) 0.444
Hoxa1 homeobox A1 0.444
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.441
Foxc2 forkhead box C2 0.440
Hmx3 H6 homeobox 3 0.434
Emid2 EMI domain containing 2 0.415
Hoxa13 homeobox A13 0.412
Ret ret proto-oncogene 0.406
En1 engrailed 1 0.404
Vax1 ventral anterior homeobox containing gene 1 0.401
Lmx1b LIM homeobox transcription factor 1 beta 0.393
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.389
Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.389
Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 0.384
Kl klotho 0.378
Drd2 dopamine receptor D2 0.374
Sim2 single-minded homolog 2 (Drosophila) 0.361
Fgf3 fibroblast growth factor 3 0.352
Esr1 estrogen receptor 1 (alpha) 0.351
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.347
Lhx3 LIM homeobox protein 3 0.345
Apc adenomatosis polyposis coli 0.339
Psmb7 proteasome (prosome, macropain) subunit, beta type 7 0.338
Foxd2 forkhead box D2 0.336
Barx2 BarH-like homeobox 2 0.316
Efna2 ephrin A2 0.314
Pou3f1 POU domain, class 3, transcription factor 1 0.313
Pou3f3 POU domain, class 3, transcription factor 3 0.309
Hoxd3 homeobox D3 0.308
Clic3 chloride intracellular channel 3 0.303
Neurog1 neurogenin 1 0.300
Hoxd9 homeobox D9 0.290
Gli1 GLI-Kruppel family member GLI1 0.287
Prrx1 paired related homeobox 1 0.285
Trp53 transformation related protein 53 0.280
Chrd chordin 0.279
Rpa1 replication protein A1 0.278
Emx1 empty spiracles homolog 1 (Drosophila) 0.275
Hoxa4 homeobox A4 0.273
Hoxa11 homeobox A11 0.270
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.256
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Rattus norvegicus
Name Description Probability Func Analog Organism
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.897
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.405
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.365
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.268
Nsfl1c NSFL1 (p97) cofactor (p47) 0.206
Vcp valosin-containing protein 0.199
Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.120
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.119
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.084
Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.062
Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.058
Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.041
Psmb5 proteasome (prosome, macropain) subunit, beta type 5 0.029
Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.024
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.022
Lin7c lin-7 homolog C (C. elegans) 0.022
Ddx1 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 0.021
Arnt aryl hydrocarbon receptor nuclear translocator 0.017
Psmb3 proteasome (prosome, macropain) subunit, beta type 3 0.014
Kars lysyl-tRNA synthetase 0.012
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.012
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.012
Gpam glycerol-3-phosphate acyltransferase, mitochondrial 0.012
Timm23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.011
Prpf38a PRP38 pre-mRNA processing factor 38 (yeast) domain containing A 0.010