The network for 'glutamate metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glutamate metabolic process

The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.

Name Description Probability Func Analog Organism
CCT8 Cct8p 0.023
PUT1 Put1p 0.018
FAA2 Faa2p 0.017
UGA1 Uga1p 0.015
GDH1 Gdh1p 0.015
LEU4 Leu4p 0.015
CPS1 Cps1p 0.015
ILV6 Ilv6p 0.015
BDH2 Bdh2p 0.015
ILV5 Ilv5p 0.015
GCY1 Gcy1p 0.014
SMM1 Smm1p 0.014
FMO1 Fmo1p 0.012
YLR264C-A hypothetical protein 0.012
NCR1 Ncr1p 0.012
YHR033W hypothetical protein 0.011
LEU2 Leu2p 0.011
YGP1 Ygp1p 0.011
SRD1 Srd1p 0.011
ALD6 Ald6p 0.011
ARG8 Arg8p 0.011
NDE1 Nde1p 0.011
MER1 Mer1p 0.010
PYC1 Pyc1p 0.010
YHB1 Yhb1p 0.010
BOP2 Bop2p 0.010
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Argk Arginine kinase 0.383
Idh Isocitrate dehydrogenase 0.290
Pgm Phosphogluconate mutase 0.204
Eno Enolase 0.113
Got2 Glutamate oxaloacetate transaminase 2 0.088
Adh Alcohol dehydrogenase 0.054
Pgd Phosphogluconate dehydrogenase 0.048
CG7920 CG7920 gene product from transcript CG7920-RA 0.046
Hex-A Hexokinase A 0.033
PyK Pyruvate kinase 0.030
CG7998 CG7998 gene product from transcript CG7998-RA 0.029
CG8036 CG8036 gene product from transcript CG8036-RB 0.023
Ras64B Ras oncogene at 64B 0.019
Zw Zwischenferment 0.019
cnn centrosomin 0.019
CG5362 CG5362 gene product from transcript CG5362-RA 0.016
CdsA CDP diglyceride synthetase 0.015
Act79B Actin 79B 0.013
CG10570 CG10570 gene product from transcript CG10570-RA 0.013
squ squash 0.013
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.012
Syt4 Synaptotagmin 4 0.011
Syt1 Synaptotagmin 1 0.011
ea easter 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
GGT1 gamma-glutamyltransferase 1 0.999
GGTLC1 gamma-glutamyltransferase light chain 1 0.999
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.991
GCLC glutamate-cysteine ligase, catalytic subunit 0.921
GGT2 gamma-glutamyltransferase 2 0.892
GCLM glutamate-cysteine ligase, modifier subunit 0.718
VDAC1 voltage-dependent anion channel 1 0.549
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.519
ERBB2IP erbb2 interacting protein 0.466
KIF5B kinesin family member 5B 0.359
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.298
GOT1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 0.280
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) 0.274
STRN3 striatin, calmodulin binding protein 3 0.258
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.247
GLUD1 glutamate dehydrogenase 1 0.223
TOM1L1 target of myb1 (chicken)-like 1 0.206
GLUD2 glutamate dehydrogenase 2 0.169
RCN3 reticulocalbin 3, EF-hand calcium binding domain 0.156
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.112
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.105
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.093
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 0.089
FBXO30 F-box protein 30 0.086
DST dystonin 0.079
GHITM growth hormone inducible transmembrane protein 0.075
FH fumarate hydratase 0.075
BTRC beta-transducin repeat containing 0.057
ATF2 activating transcription factor 2 0.053
ZRANB1 zinc finger, RAN-binding domain containing 1 0.051
ZFP106 zinc finger protein 106 homolog (mouse) 0.047
GIGYF2 GRB10 interacting GYF protein 2 0.045
MACF1 microtubule-actin crosslinking factor 1 0.041
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.037
RECQL5 RecQ protein-like 5 0.034
ACLY ATP citrate lyase 0.030
PKP4 plakophilin 4 0.030
YARS tyrosyl-tRNA synthetase 0.029
RANBP2 RAN binding protein 2 0.029
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.025
MTCH2 mitochondrial carrier homolog 2 (C. elegans) 0.024
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.023
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.023
AARS alanyl-tRNA synthetase 0.023
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.021
SORD sorbitol dehydrogenase 0.021
GSR glutathione reductase 0.020
SCRIB scribbled homolog (Drosophila) 0.020
PEBP1 phosphatidylethanolamine binding protein 1 0.019
TMX2 thioredoxin-related transmembrane protein 2 0.018
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.018
PSEN1 presenilin 1 0.017
NME2 non-metastatic cells 2, protein (NM23B) expressed in 0.016
COQ9 coenzyme Q9 homolog (S. cerevisiae) 0.016
PCCB propionyl CoA carboxylase, beta polypeptide 0.016
KIAA1370 KIAA1370 0.016
TCTN3 tectonic family member 3 0.015
ANKRD17 ankyrin repeat domain 17 0.015
SYNE1 spectrin repeat containing, nuclear envelope 1 0.014
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.014
GLIS2 GLIS family zinc finger 2 0.013
AXIN1 axin 1 0.013
HADH hydroxyacyl-CoA dehydrogenase 0.013
HECTD1 HECT domain containing 1 0.013
APOO apolipoprotein O 0.013
KIFAP3 kinesin-associated protein 3 0.012
IDE insulin-degrading enzyme 0.012
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.012
JUP junction plakoglobin 0.012
CTNNBIP1 catenin, beta interacting protein 1 0.011
MIPEP mitochondrial intermediate peptidase 0.011
DLAT dihydrolipoamide S-acetyltransferase 0.011
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.011
AFG3L2 AFG3 ATPase family gene 3-like 2 (S. cerevisiae) 0.010
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Lep leptin 0.885
Rxra retinoid X receptor alpha 0.733
Lepr leptin receptor 0.632
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.345
Apoe apolipoprotein E 0.327
Immt inner membrane protein, mitochondrial 0.281
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.281
Nos1 nitric oxide synthase 1, neuronal 0.259
Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) 0.248
Gabrd gamma-aminobutyric acid (GABA) A receptor, subunit delta 0.230
Smad3 MAD homolog 3 (Drosophila) 0.212
Tgfb1 transforming growth factor, beta 1 0.196
Nos2 nitric oxide synthase 2, inducible 0.166
Gpr12 G-protein coupled receptor 12 0.144
Insr insulin receptor 0.135
Esr1 estrogen receptor 1 (alpha) 0.127
Scd1 stearoyl-Coenzyme A desaturase 1 0.124
Dlg4 discs, large homolog 4 (Drosophila) 0.122
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.107
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.105
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.101
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.092
Aldob aldolase B, fructose-bisphosphate 0.090
Thrb thyroid hormone receptor beta 0.085
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.084
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.083
Plin1 perilipin 1 0.081
Pparg peroxisome proliferator activated receptor gamma 0.079
Hr hairless 0.068
Hgd homogentisate 1, 2-dioxygenase 0.063
Cps1 carbamoyl-phosphate synthetase 1 0.062
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.062
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.060
Rdh16 retinol dehydrogenase 16 0.060
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.059
Iyd iodotyrosine deiodinase 0.057
Pipox pipecolic acid oxidase 0.057
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.056
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.050
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.049
Kl klotho 0.049
Syt1 synaptotagmin I 0.049
Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 0.048
Slc4a4 solute carrier family 4 (anion exchanger), member 4 0.048
Asgr2 asialoglycoprotein receptor 2 0.045
Notch2 Notch gene homolog 2 (Drosophila) 0.043
Adra1b adrenergic receptor, alpha 1b 0.043
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.043
Odz1 odd Oz/ten-m homolog 1 (Drosophila) 0.040
B3galt1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.040
Nln neurolysin (metallopeptidase M3 family) 0.039
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.038
Got1 glutamate oxaloacetate transaminase 1, soluble 0.037
G6pc glucose-6-phosphatase, catalytic 0.036
Nos3 nitric oxide synthase 3, endothelial cell 0.036
Cat catalase 0.035
Csf1 colony stimulating factor 1 (macrophage) 0.034
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.034
Gjb1 gap junction protein, beta 1 0.034
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.033
Mobp myelin-associated oligodendrocytic basic protein 0.032
Vdac1 voltage-dependent anion channel 1 0.032
Bscl2 Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) 0.032
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.032
Tlr4 toll-like receptor 4 0.031
Irs2 insulin receptor substrate 2 0.031
Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial 0.031
Lipe lipase, hormone sensitive 0.030
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 0.030
Sult1d1 sulfotransferase family 1D, member 1 0.030
Tat tyrosine aminotransferase 0.030
Gckr glucokinase regulatory protein 0.030
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.030
Hccs holocytochrome c synthetase 0.030
Abcg5 ATP-binding cassette, sub-family G (WHITE), member 5 0.030
Pcx pyruvate carboxylase 0.029
Pnpla2 patatin-like phospholipase domain containing 2 0.029
Npy2r neuropeptide Y receptor Y2 0.028
Apoa1 apolipoprotein A-I 0.027
Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial 0.026
Sik3 SIK family kinase 3 0.026
Ngef neuronal guanine nucleotide exchange factor 0.025
Slc26a1 solute carrier family 26 (sulfate transporter), member 1 0.025
Lipa lysosomal acid lipase A 0.025
Orm3 orosomucoid 3 0.025
Tdo2 tryptophan 2,3-dioxygenase 0.025
Ldlr low density lipoprotein receptor 0.025
Hnf4a hepatic nuclear factor 4, alpha 0.025
Gad2 glutamic acid decarboxylase 2 0.024
Il10 interleukin 10 0.024
Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 0.024
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.024
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.023
Vav2 vav 2 oncogene 0.023
Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A 0.023
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.023
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.023
Acads acyl-Coenzyme A dehydrogenase, short chain 0.023
Plg plasminogen 0.023
Sult1b1 sulfotransferase family 1B, member 1 0.022
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.146
Tufm Tu translation elongation factor, mitochondrial 0.050
Nnt nicotinamide nucleotide transhydrogenase 0.038
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.021
Trap1 TNF receptor-associated protein 1 0.020
Cabc1 chaperone, ABC1 activity of bc1 complex homolog (S. pombe) 0.016
Mcf2l MCF.2 cell line derived transforming sequence-like 0.015
Nsf N-ethylmaleimide-sensitive factor 0.014
Glud1 glutamate dehydrogenase 1 0.014
G6pc glucose-6-phosphatase, catalytic subunit 0.013
Vdac1 voltage-dependent anion channel 1 0.013
Map1lc3b microtubule-associated protein 1 light chain 3 beta 0.013
Mfn2 mitofusin 2 0.013
Ppa2 pyrophosphatase (inorganic) 2 0.012
Rasgrp1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.011
Aldh1a1 aldehyde dehydrogenase 1 family, member A1 0.011
Cntn4 contactin 4 0.011
Ldhb lactate dehydrogenase B 0.011
Ndrg2 N-myc downstream regulated gene 2 0.011
Pah phenylalanine hydroxylase 0.011
Chgb chromogranin B 0.010
Hibadh 3-hydroxyisobutyrate dehydrogenase 0.010
Gstt2 glutathione S-transferase, theta 2 0.010