The network for 'negative regulation of protein complex disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of protein complex disassembly

Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.

Name Description Probability Func Analog Organism
CAP2 Cap2p 0.243
GBP2 Gbp2p 0.157
BOI1 Boi1p 0.155
KAR9 Kar9p 0.136
ABP1 Abp1p 0.109
CLB3 Clb3p 0.092
MYO5 Myo5p 0.091
BMH1 Bmh1p 0.075
SRV2 Srv2p 0.065
VIK1 Vik1p 0.050
CLB1 Clb1p 0.047
CIK1 Cik1p 0.044
BIK1 Bik1p 0.043
CDC6 Cdc6p 0.043
CIN8 Cin8p 0.043
GYL1 Gyl1p 0.040
ASE1 Ase1p 0.038
ENT3 Ent3p 0.033
KEL1 Kel1p 0.031
BNI1 Bni1p 0.030
TWF1 Twf1p 0.029
AIR1 Air1p 0.029
ARC40 Arc40p 0.029
ACM1 Acm1p 0.027
CDC24 Cdc24p 0.026
KAR3 Kar3p 0.025
DAM1 Dam1p 0.025
KIP1 Kip1p 0.024
YFR016C hypothetical protein 0.022
BBC1 Bbc1p 0.022
BRN1 Brn1p 0.022
LAS17 Las17p 0.021
YPL014W hypothetical protein 0.021
BMH2 Bmh2p 0.020
CLB4 Clb4p 0.020
LSB1 Lsb1p 0.020
DYN1 Dyn1p 0.020
DYN3 Dyn3p 0.019
CDC14 Cdc14p 0.019
NIS1 Nis1p 0.018
CLB6 Clb6p 0.018
SRD1 Srd1p 0.018
YLR264C-A hypothetical protein 0.018
YPR1 Ypr1p 0.018
YTA6 Yta6p 0.018
GLC7 Glc7p 0.018
SLI15 Sli15p 0.018
AIM21 Aim21p 0.017
CKS1 Cks1p 0.017
ORC6 Orc6p 0.017
HST3 Hst3p 0.017
KCC4 Kcc4p 0.017
LEU2 Leu2p 0.016
STB1 Stb1p 0.016
YOL038C-A hypothetical protein 0.016
ARP10 Arp10p 0.016
YLR162W hypothetical protein 0.016
ASK1 Ask1p 0.015
SPL2 Spl2p 0.015
MEX67 Mex67p 0.015
BZZ1 Bzz1p 0.015
SKM1 Skm1p 0.015
CDC28 Cdc28p 0.015
MF(ALPHA)2 Mf(alpha)2p 0.015
SLK19 Slk19p 0.015
HO Hop 0.015
NDD1 Ndd1p 0.015
BIM1 Bim1p 0.015
ARG8 Arg8p 0.015
FIR1 Fir1p 0.014
MER1 Mer1p 0.014
NUD1 Nud1p 0.014
SGN1 Sgn1p 0.014
PHM6 Phm6p 0.014
HXT3 Hxt3p 0.014
MF(ALPHA)1 Mf(alpha)1p 0.013
YGL015C hypothetical protein 0.013
YBR013C hypothetical protein 0.013
YAR068W hypothetical protein 0.013
ADH2 Adh2p 0.013
CAK1 Cak1p 0.013
ZPS1 Zps1p 0.013
GDI1 Gdi1p 0.013
SIC1 Sic1p 0.013
SPR6 Spr6p 0.013
ARE2 Are2p 0.013
THP2 Thp2p 0.013
KIP3 Kip3p 0.013
CPD1 Cpd1p 0.013
TYE7 Tye7p 0.013
ATP6 Atp6p 0.013
SAC6 Sac6p 0.013
HPF1 Hpf1p 0.013
YNL058C hypothetical protein 0.012
YLR042C hypothetical protein 0.012
SCP1 Scp1p 0.012
SPS4 Sps4p 0.012
PFY1 Pfy1p 0.012
SPC29 Spc29p 0.012
YPR157W hypothetical protein 0.012
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Det Deterin 0.913
exo84 CG6095 gene product from transcript CG6095-RA 0.887
bru brunelleschi 0.754
dia diaphanous 0.732
Klp67A Kinesin-like protein at 67A 0.667
CG32038 CG32038 gene product from transcript CG32038-RA 0.603
asp abnormal spindle 0.562
alpha-Spec alpha Spectrin 0.560
tef teflon 0.459
Dhc64C Dynein heavy chain 64C 0.290
sec8 CG2095 gene product from transcript CG2095-RA 0.244
vib vibrator 0.229
mars CG17064 gene product from transcript CG17064-RB 0.225
vas vasa 0.212
gwl greatwall 0.206
neb nebbish 0.170
sls sallimus 0.165
flw flapwing 0.138
beta-Spec beta Spectrin 0.124
sqh spaghetti squash 0.123
Sas-4 CG10061 gene product from transcript CG10061-RA 0.117
msps mini spindles 0.116
wupA wings up A 0.116
Spc25 CG7242 gene product from transcript CG7242-RA 0.111
polo CG12306 gene product from transcript CG12306-RA 0.103
Pak3 CG14895 gene product from transcript CG14895-RA 0.098
Caps Calcium activated protein for secretion 0.095
CG31224 CG31224 gene product from transcript CG31224-RA 0.090
ph-p polyhomeotic proximal 0.088
Ppcs Phosphopantothenoylcysteine synthetase 0.087
RfC4 Replication factor C subunit 4 0.078
Orc2 Origin recognition complex subunit 2 0.078
ball ballchen 0.077
Sop2 Suppressor of profilin 2 0.076
aust australin 0.074
Unc-76 CG3981 gene product from transcript CG3981-RB 0.073
scra scraps 0.073
Poc1 Proteome of centrioles 1 0.073
aret arrest 0.072
WASp CG1520 gene product from transcript CG1520-RA 0.071
hts hu li tai shao 0.070
borr borealin-related 0.066
bond james bond 0.062
ana3 anastral spindle 3 0.062
eIF4G2 eukaryotic translation initiation factor 4G2 0.060
Actn alpha actinin 0.060
cher cheerio 0.055
Cp110 CG14617 gene product from transcript CG14617-RB 0.054
Lasp CG3849 gene product from transcript CG3849-RB 0.053
CG11329 CG11329 gene product from transcript CG11329-RA 0.053
flr flare 0.052
CG9247 CG9247 gene product from transcript CG9247-RA 0.049
pcx pecanex 0.046
Zasp52 Z band alternatively spliced PDZ-motif protein 52 0.046
Zasp66 Z band alternatively spliced PDZ-motif protein 66 0.045
sas-6 spindle assembly abnormal 6 0.044
Marf Mitochondrial assembly regulatory factor 0.043
Act5C Actin 5C 0.043
DAAM Dishevelled Associated Activator of Morphogenesis 0.042
CG11299 CG11299 gene product from transcript CG11299-RA 0.041
Ino80 CG31212 gene product from transcript CG31212-RA 0.040
Vrp1 Verprolin 1 0.040
Cog7 CG31040 gene product from transcript CG31040-RA 0.040
asl asterless 0.040
Mrtf Myocardin-related transcription factor 0.039
Mlc2 Myosin light chain 2 0.037
Cenp-C CG31258 gene product from transcript CG31258-RA 0.036
LamC Lamin C 0.035
CG11033 CG11033 gene product from transcript CG11033-RB 0.035
ana2 anastral spindle 2 0.034
mtrm matrimony 0.031
Arp66B Actin-related protein 66B 0.031
egl egalitarian 0.030
DNApol-alpha60 DNA polymerase alpha 60kD 0.030
zpg zero population growth 0.029
par-6 CG5884 gene product from transcript CG5884-RA 0.028
enc encore 0.028
lkb1 CG9374 gene product from transcript CG9374-RJ 0.027
sals sarcomere length short 0.027
cindr CIN85 and CD2AP orthologue 0.027
Rae1 CG9862 gene product from transcript CG9862-RA 0.026
Gef26 CG9491 gene product from transcript CG9491-RB 0.026
synj synaptojanin 0.025
CG10260 CG10260 gene product from transcript CG10260-RB 0.024
larp La related protein 0.024
cmet CENP-meta 0.024
Ndc80 CG9938 gene product from transcript CG9938-RA 0.024
ncd non-claret disjunctional 0.023
CycB3 Cyclin B3 0.023
CG14215 CG14215 gene product from transcript CG14215-RA 0.023
otu ovarian tumor 0.022
sec5 CG8843 gene product from transcript CG8843-RA 0.022
Grip75 CG6176 gene product from transcript CG6176-RA 0.021
nudE CG8104 gene product from transcript CG8104-RB 0.021
CG5674 CG5674 gene product from transcript CG5674-RB 0.020
stwl stonewall 0.020
opa1-like optic atrophy 1-like 0.020
Grip128 CG9201 gene product from transcript CG9201-RB 0.020
Cep135 CG17081 gene product from transcript CG17081-RB 0.020
tai taiman 0.020
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Homo sapiens
Name Description Probability Func Analog Organism
IRAK2 interleukin-1 receptor-associated kinase 2 0.814
TPM2 tropomyosin 2 (beta) 0.506
MYH9 myosin, heavy chain 9, non-muscle 0.365
TRIM63 tripartite motif containing 63 0.294
IRAK1 interleukin-1 receptor-associated kinase 1 0.226
FLNA filamin A, alpha 0.223
RACGAP1 Rac GTPase activating protein 1 0.214
ACTN1 actinin, alpha 1 0.199
APC adenomatous polyposis coli 0.198
TEX11 testis expressed 11 0.189
MYD88 myeloid differentiation primary response gene (88) 0.170
PDLIM7 PDZ and LIM domain 7 (enigma) 0.164
SASS6 spindle assembly 6 homolog (C. elegans) 0.164
EXOC1 exocyst complex component 1 0.142
TPM1 tropomyosin 1 (alpha) 0.125
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.124
MARK2 MAP/microtubule affinity-regulating kinase 2 0.109
INCENP inner centromere protein antigens 135/155kDa 0.102
TRAF6 TNF receptor-associated factor 6 0.098
CKS2 CDC28 protein kinase regulatory subunit 2 0.096
CDK2 cyclin-dependent kinase 2 0.088
RIPK3 receptor-interacting serine-threonine kinase 3 0.086
KIF1B kinesin family member 1B 0.085
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.083
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.081
PSEN2 presenilin 2 (Alzheimer disease 4) 0.080
ZYX zyxin 0.080
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.078
FLNB filamin B, beta 0.077
RAD21 RAD21 homolog (S. pombe) 0.076
EXOC2 exocyst complex component 2 0.075
GLIS2 GLIS family zinc finger 2 0.071
TPM4 tropomyosin 4 0.070
MYPN myopalladin 0.069
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.066
CCNB2 cyclin B2 0.059
CNN2 calponin 2 0.057
KIF20A kinesin family member 20A 0.057
ANKRD28 ankyrin repeat domain 28 0.055
CENPE centromere protein E, 312kDa 0.054
LBR lamin B receptor 0.054
ADRBK1 adrenergic, beta, receptor kinase 1 0.047
PELI3 pellino homolog 3 (Drosophila) 0.046
HABP4 hyaluronan binding protein 4 0.045
XPO1 exportin 1 (CRM1 homolog, yeast) 0.044
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.043
STK3 serine/threonine kinase 3 0.039
KIF23 kinesin family member 23 0.038
TWF2 twinfilin, actin-binding protein, homolog 2 (Drosophila) 0.037
CCNB1 cyclin B1 0.037
PBK PDZ binding kinase 0.034
ROD1 ROD1 regulator of differentiation 1 (S. pombe) 0.033
TTN titin 0.033
GAS2L3 growth arrest-specific 2 like 3 0.032
TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis) 0.032
TNIP1 TNFAIP3 interacting protein 1 0.031
AKAP9 A kinase (PRKA) anchor protein (yotiao) 9 0.030
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.030
LMNA lamin A/C 0.030
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.030
IRAK3 interleukin-1 receptor-associated kinase 3 0.030
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.030
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.030
BIRC5 baculoviral IAP repeat containing 5 0.029
CDK1 cyclin-dependent kinase 1 0.029
CORO1C coronin, actin binding protein, 1C 0.028
CCDC85A coiled-coil domain containing 85A 0.027
MYL9 myosin, light chain 9, regulatory 0.027
SUFU suppressor of fused homolog (Drosophila) 0.027
DEK DEK oncogene 0.024
HMGB2 high mobility group box 2 0.024
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.024
CENPJ centromere protein J 0.024
ERBB2IP erbb2 interacting protein 0.023
EXOC7 exocyst complex component 7 0.023
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.023
CD2AP CD2-associated protein 0.022
SVIL supervillin 0.022
WASL Wiskott-Aldrich syndrome-like 0.022
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.022
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.022
KIF5B kinesin family member 5B 0.022
SQSTM1 sequestosome 1 0.021
ACTA1 actin, alpha 1, skeletal muscle 0.020
KIF4A kinesin family member 4A 0.020
ZRANB1 zinc finger, RAN-binding domain containing 1 0.020
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.020
CKAP5 cytoskeleton associated protein 5 0.019
CCNE1 cyclin E1 0.019
GRB2 growth factor receptor-bound protein 2 0.019
GPSM2 G-protein signaling modulator 2 0.019
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.019
VCL vinculin 0.019
NBR1 neighbor of BRCA1 gene 1 0.018
TMPO thymopoietin 0.018
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.018
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.018
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.018
MYCBP2 MYC binding protein 2 0.018
CYLD cylindromatosis (turban tumor syndrome) 0.017
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Mus musculus
Name Description Probability Func Analog Organism
Cry2 cryptochrome 2 (photolyase-like) 0.998
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.980
Clock circadian locomotor output cycles kaput 0.954
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.871
Macf1 microtubule-actin crosslinking factor 1 0.856
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.787
Arpc4 actin related protein 2/3 complex, subunit 4 0.742
Wdr1 WD repeat domain 1 0.732
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.676
Dclk1 doublecortin-like kinase 1 0.651
Cry1 cryptochrome 1 (photolyase-like) 0.644
Anln anillin, actin binding protein 0.597
Usp2 ubiquitin specific peptidase 2 0.586
Dcx doublecortin 0.481
Capzb capping protein (actin filament) muscle Z-line, beta 0.474
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.439
Kif20a kinesin family member 20A 0.429
Braf Braf transforming gene 0.423
Cdk1 cyclin-dependent kinase 1 0.397
Trim63 tripartite motif-containing 63 0.397
Pfn1 profilin 1 0.280
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.276
Clasp1 CLIP associating protein 1 0.268
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.267
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.262
Csrp1 cysteine and glycine-rich protein 1 0.258
Csnk1e casein kinase 1, epsilon 0.242
Ccna2 cyclin A2 0.241
Lepr leptin receptor 0.238
2500003M10Rik RIKEN cDNA 2500003M10 gene 0.204
Trim55 tripartite motif-containing 55 0.196
Smc4 structural maintenance of chromosomes 4 0.184
Vasp vasodilator-stimulated phosphoprotein 0.171
Lbr lamin B receptor 0.169
Kif11 kinesin family member 11 0.168
Racgap1 Rac GTPase-activating protein 1 0.165
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.161
Btrc beta-transducin repeat containing protein 0.160
Shc3 src homology 2 domain-containing transforming protein C3 0.151
Ctnnb1 catenin (cadherin associated protein), beta 1 0.148
Ckap2 cytoskeleton associated protein 2 0.143
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 0.137
Dbnl drebrin-like 0.123
Prc1 protein regulator of cytokinesis 1 0.118
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.117
Ppp4c protein phosphatase 4, catalytic subunit 0.115
Fzr1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.115
Akt1 thymoma viral proto-oncogene 1 0.109
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.108
Gnb1 guanine nucleotide binding protein (G protein), beta 1 0.108
Birc5 baculoviral IAP repeat-containing 5 0.103
Rb1 retinoblastoma 1 0.100
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.099
Tfdp1 transcription factor Dp 1 0.099
Traf6 TNF receptor-associated factor 6 0.098
Mstn myostatin 0.098
Anapc2 anaphase promoting complex subunit 2 0.096
Fgf14 fibroblast growth factor 14 0.091
Cltc clathrin, heavy polypeptide (Hc) 0.090
Fam49b family with sequence similarity 49, member B 0.088
Smc2 structural maintenance of chromosomes 2 0.086
Mki67 antigen identified by monoclonal antibody Ki 67 0.086
Dck deoxycytidine kinase 0.083
Ect2 ect2 oncogene 0.083
Arhgap1 Rho GTPase activating protein 1 0.082
Sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) 0.081
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.079
Bzw1 basic leucine zipper and W2 domains 1 0.072
Smad3 MAD homolog 3 (Drosophila) 0.072
Sept7 septin 7 0.072
Abi1 abl-interactor 1 0.071
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.071
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.071
Spna2 spectrin alpha 2 0.070
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.069
Fgfbp1 fibroblast growth factor binding protein 1 0.067
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.064
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.062
Depdc1a DEP domain containing 1a 0.062
Rhoa ras homolog gene family, member A 0.060
Tef thyrotroph embryonic factor 0.060
Pgr progesterone receptor 0.059
Myo1c myosin IC 0.058
Hnrnpm heterogeneous nuclear ribonucleoprotein M 0.057
Trp53 transformation related protein 53 0.057
Tuba1a tubulin, alpha 1A 0.057
Rac1 RAS-related C3 botulinum substrate 1 0.055
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.054
Gipc1 GIPC PDZ domain containing family, member 1 0.054
Dtna dystrobrevin alpha 0.054
Tubb5 tubulin, beta 5 0.053
Mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.053
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.052
Lmna lamin A 0.050
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.050
Wdr82 WD repeat domain containing 82 0.049
Top2a topoisomerase (DNA) II alpha 0.049
Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 0.048
Slc25a24 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 0.048
Ilk integrin linked kinase 0.046
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Rattus norvegicus
Name Description Probability Func Analog Organism
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.043
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.033
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.028
Acta2 smooth muscle alpha-actin 0.026
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.024
Tagln transgelin 0.017
Actb actin, beta 0.011