The network for 'cellular response to nutrient levels' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to nutrient levels

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ATG1 Atg1p 0.976
VPS30 Vps30p 0.956
RTG3 Rtg3p 0.936
RIM101 Rim101p 0.923
ATG12 Atg12p 0.907
SNF1 Snf1p 0.871
ATG3 Atg3p 0.860
MSN2 Msn2p 0.859
TOR1 Tor1p 0.845
ATG4 Atg4p 0.837
HSP82 Hsp82p 0.821
GLN3 Gln3p 0.790
SNF4 Snf4p 0.771
SNF2 Snf2p 0.764
ATG21 Atg21p 0.735
ATG7 Atg7p 0.729
VPS36 Vps36p 0.710
GAL11 Gal11p 0.709
TPK1 Tpk1p 0.701
ESA1 Esa1p 0.680
ATG13 Atg13p 0.646
ATG23 Atg23p 0.636
HSP32 Hsp32p 0.620
VPS27 Vps27p 0.602
HSV2 Hsv2p 0.593
ATG9 Atg9p 0.582
NET1 Net1p 0.576
SEC2 Sec2p 0.551
PEP5 Pep5p 0.545
MKS1 Mks1p 0.543
KSP1 Ksp1p 0.540
SSN3 Ssn3p 0.531
ASP3-3 Asp3-3p 0.528
ASP3-4 Asp3-4p 0.525
PHO11 Pho11p 0.522
CIS1 Cis1p 0.521
ASP3-2 Asp3-2p 0.518
ASP3-1 Asp3-1p 0.513
ENA5 Ena5p 0.489
ATG29 Atg29p 0.474
VPS41 Vps41p 0.467
SNF5 Snf5p 0.461
VAC7 Vac7p 0.459
KIC1 Kic1p 0.445
NPR2 Npr2p 0.444
GAL4 Gal4p 0.430
HSP33 Hsp33p 0.420
ATG11 Atg11p 0.412
SNO4 Sno4p 0.405
SNX4 Snx4p 0.400
SHP1 Shp1p 0.398
RTS3 Rts3p 0.390
COG3 Cog3p 0.389
ATG16 Atg16p 0.387
ATG14 Atg14p 0.382
SNF8 Snf8p 0.359
VPS28 Vps28p 0.357
YPT1 Ypt1p 0.352
PHO12 Pho12p 0.351
YKR015C hypothetical protein 0.346
DOT6 Dot6p 0.346
HAP4 Hap4p 0.345
YGR250C hypothetical protein 0.335
ATG20 Atg20p 0.332
VHS1 Vhs1p 0.320
GPR1 Gpr1p 0.310
KEM1 Kem1p 0.304
MIG3 Mig3p 0.302
STP2 Stp2p 0.294
GLK1 Glk1p 0.290
GAL3 Gal3p 0.276
MSS4 Mss4p 0.275
ISW2 Isw2p 0.273
COG6 Cog6p 0.271
PHO81 Pho81p 0.270
STE2 Ste2p 0.267
ISW1 Isw1p 0.260
SOD1 Sod1p 0.258
BOI1 Boi1p 0.258
KDX1 Kdx1p 0.250
VPS16 Vps16p 0.250
VPS8 Vps8p 0.245
PCL2 Pcl2p 0.244
CAT8 Cat8p 0.241
ATG10 Atg10p 0.240
ENA2 Ena2p 0.240
MAM3 Mam3p 0.239
ATG5 Atg5p 0.237
ADR1 Adr1p 0.237
SNF6 Snf6p 0.234
SSK1 Ssk1p 0.234
PFK1 Pfk1p 0.233
KGD1 Kgd1p 0.233
IRC15 Irc15p 0.232
SSD1 Ssd1p 0.229
FIG4 Fig4p 0.224
SWI1 Swi1p 0.224
MON1 Mon1p 0.213
CLN1 Cln1p 0.212
VID22 Vid22p 0.212
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.497
atg-18 Protein ATG-18 0.377
ifg-1 Protein IFG-1 0.122
asah-1 Protein ASAH-1 0.073
egl-46 Protein EGL-46 0.063
pmt-1 Protein PMT-1 0.062
cnd-1 Protein CND-1 0.055
rpn-2 Protein RPN-2 0.054
lin-45 Protein LIN-45 0.052
F57F5.1 Protein F57F5.1 0.052
elt-6 Protein ELT-6 0.052
hnd-1 Protein HND-1 0.051
unc-62 Protein UNC-62 0.047
ran-2 Protein RAN-2 0.037
K10C8.3 Protein K10C8.3 0.036
mtm-9 Protein MTM-9 0.035
pal-1 Protein PAL-1 0.035
dcn-1 Protein DCN-1 0.035
utx-1 Protein UTX-1 0.034
pad-1 Protein PAD-1 0.033
cdk-9 Protein CDK-9 0.033
CELE_C01G6.4 Protein C01G6.4 0.032
CELE_F19F10.11 Protein F19F10.11 0.028
sur-2 Protein SUR-2 0.028
CELE_Y57G11C.15 Protein Y57G11C.15 0.027
npp-4 Protein NPP-4 0.027
T07F12.4 Protein T07F12.4 0.027
tbc-9 Protein TBC-9 0.026
Y82E9BR.13 Protein Y82E9BR.13 0.025
cpr-4 Protein CPR-4 0.025
Y76A2B.4 Protein Y76A2B.4 0.024
C02F12.8 Protein C02F12.8 0.024
atg-16.1 Protein ATG-16.1 0.024
scl-2 Protein SCL-2 0.023
dnj-25 Protein DNJ-25 0.023
gsp-1 Protein GSP-1 0.023
pmk-1 Protein PMK-1 0.023
T25B9.8 Protein T25B9.8 0.022
ptr-8 Protein PTR-8 0.022
uba-1 Protein UBA-1 0.021
eor-1 Protein EOR-1 0.021
CELE_H28G03.1 Protein H28G03.1 0.021
che-13 Protein CHE-13 0.021
amx-1 Protein AMX-1 0.020
lon-2 Protein LON-2 0.020
atg-13 Protein ATG-13 0.020
lir-2 Protein LIR-2 0.019
tam-1 Protein TAM-1 0.019
F37B4.10 Protein F37B4.10 0.019
lin-12 Protein LIN-12 0.019
unc-130 Protein UNC-130 0.018
smk-1 Protein SMK-1 0.018
gld-2 Protein GLD-2 0.018
pdhk-2 Protein PDHK-2 0.018
bbs-5 Protein BBS-5 0.018
mca-2 Protein MCA-2 0.017
che-11 Protein CHE-11 0.017
hif-1 Protein HIF-1 0.017
apr-1 Protein APR-1 0.016
R13A5.9 Protein R13A5.9 0.016
him-1 Protein HIM-1 0.016
dsh-2 Protein DSH-2 0.016
tag-77 Protein TAG-77 0.016
clec-65 Protein CLEC-65 0.016
rpl-3 Protein RPL-3 0.016
fkh-2 Protein FKH-2 0.015
R12C12.8 Protein R12C12.8 0.015
ges-1 Protein GES-1 0.015
ess-2 Protein ESS-2 0.015
fozi-1 Protein FOZI-1 0.015
pop-1 Protein POP-1 0.015
vps-34 Protein VPS-34 0.014
inx-3 Protein INX-3 0.014
pbrm-1 Protein PBRM-1 0.014
pdi-3 Protein PDI-3 0.014
clec-50 Protein CLEC-50 0.014
C09E7.4 Protein C09E7.4 0.014
CELE_F10G7.5 Protein F10G7.5 0.014
clh-3 Protein CLH-3 0.014
Y51F10.7 Protein Y51F10.7 0.013
C30C11.4 Protein C30C11.4 0.013
lin-36 Protein LIN-36 0.013
spp-8 Protein SPP-8 0.013
acly-2 Protein ACLY-2 0.013
F53F10.2 Protein F53F10.2 0.013
Y67D8C.3 Protein Y67D8C.3 0.013
cfim-2 Protein CFIM-2 0.013
nphp-4 Protein NPHP-4 0.013
C05G5.2 Protein C05G5.2 0.013
cogc-2 Protein COGC-2 0.013
pme-3 Protein PME-3 0.012
CELE_F53H1.1 Protein F53H1.1 0.012
F45F2.10 Protein F45F2.10 0.012
anc-1 Protein ANC-1 0.012
nhr-70 Protein NHR-70 0.012
abts-3 Protein ABTS-3 0.012
CELE_C44C10.4 Protein C44C10.4 0.012
let-756 Protein LET-756 0.012
lap-2 Protein LAP-2 0.012
unc-11 Protein UNC-11 0.012
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
dag1 dystroglycan 1 0.821
foxa3 forkhead box A3 0.540
mapk3 mitogen-activated protein kinase 3 0.532
spry4 sprouty (Drosophila) homolog 4 0.419
ihha Indian hedgehog homolog a 0.389
bmp4 bone morphogenetic protein 4 0.366
ptgs1 prostaglandin-endoperoxide synthase 1 0.344
foxa2 forkhead box A2 0.327
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.308
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.283
ef1a elongation factor 1-alpha 0.276
sox9b SRY-box containing gene 9b 0.266
fgf3 fibroblast growth factor 3 0.260
bcl2l1 bcl2-like 1 0.247
LOC560602 novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6) 0.247
npc1 Niemann-Pick disease, type C1 0.245
slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 0.244
rab1a RAB1A, member RAS oncogene family 0.231
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.230
cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.226
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.222
f2r coagulation factor II (thrombin) receptor 0.213
nrg2a neuregulin 2a 0.211
notch3 notch homolog 3 0.210
myf5 myogenic factor 5 0.206
wnt10a wingless-type MMTV integration site family, member 10a 0.204
sox9a SRY-box containing gene 9a 0.202
tm9sf2 transmembrane 9 superfamily member 2 0.201
ctsf cathepsin F 0.197
ucp2 uncoupling protein 2 0.195
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.188
ncor1 nuclear receptor co-repressor 1 0.181
frem3 Fras1 related extracellular matrix 3 0.178
baxa bcl2-associated X protein, a 0.178
klf4a Kruppel-like transcription factor 4a 0.178
bmp2b bone morphogenetic protein 2b 0.176
rbp4 retinol binding protein 4, plasma 0.174
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.171
lama5 laminin, alpha 5 0.169
bmpr2a bone morphogenetic protein receptor, type II a (serine/threonine kinase) 0.169
gpia glucose phosphate isomerase a 0.166
itgb1a integrin, beta 1a 0.166
zgc:66100 zgc:66100 0.165
ctsl1a cathepsin L, 1 a 0.165
ikbkg inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.160
itgb1b.1 integrin, beta 1b.1 0.158
ctsd cathepsin D 0.157
tgfbr2 transforming growth factor, beta receptor II 0.151
tax1bp1b Tax1 (human T-cell leukemia virus type I) binding protein 1b 0.150
LOC565459 tight junction protein ZO-1-like 0.146
tob1a transducer of ERBB2, 1a 0.142
slc26a3 solute carrier family 26, member 3 0.141
lats1 LATS, large tumor suppressor, homolog 1 (Drosophila) 0.140
ptgs2a prostaglandin-endoperoxide synthase 2a 0.140
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.140
grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.140
col5a1 procollagen, type V, alpha 1 0.138
rest RE1-silencing transcription factor 0.138
ift57 intraflagellar transport protein 57 0.136
sdf4 stromal cell derived factor 4 0.135
spry2 sprouty homolog 2 0.133
syap1 synapse associated protein 1 0.133
hnf1ba HNF1 homeobox Ba 0.132
gro2 groucho 2 0.129
frzb frizzled-related protein 0.128
ids iduronate 2-sulfatase 0.127
ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.124
fn1 fibronectin 1 0.124
cops3 COP9 constitutive photomorphogenic homolog subunit 3 0.124
abcf1 ATP-binding cassette, sub-family F (GCN20), member 1 0.121
nr3c2 nuclear receptor subfamily 3, group C, member 2 0.121
mst1 macrophage stimulating 1 (hepatocyte growth factor-like) 0.120
zgc:158603 zgc:158603 0.119
gclc glutamate-cysteine ligase, catalytic subunit 0.119
itgb1b integrin, beta 1b 0.118
vdra vitamin D receptor a 0.117
snx12 sorting nexin 12 0.116
fzd7b frizzled homolog 7b 0.116
creb3l3l cAMP responsive element binding protein 3-like 3 like 0.116
faf2 Fas associated factor family member 2 0.114
rab2a RAB2A, member RAS oncogene family 0.113
ext2 exostoses (multiple) 2 0.112
sult2st2 sulfotransferase family 2, cytosolic sulfotransferase 2 0.111
tgfbi transforming growth factor, beta-induced 0.110
zfand5a zinc finger, AN1-type domain 5a 0.110
ptena phosphatase and tensin homolog A 0.109
fn1b fibronectin 1b 0.108
brd2a bromodomain-containing 2a 0.108
wnt11r wingless-type MMTV integration site family, member 11, related 0.108
zbtb4 zinc finger and BTB domain containing 4 0.107
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.106
naa15b N(alpha)-acetyltransferase 15, NatA auxiliary subunit b 0.105
bhlhe40 basic helix-loop-helix family, member e40 0.105
arf5 ADP-ribosylation factor 5 0.104
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.104
kdm5c lysine (K)-specific demethylase 5C 0.104
zgc:56010 zgc:56010 0.104
wnt4b wingless-type MMTV integration site family, member 4b 0.102
cdkn1a cyclin-dependent kinase inhibitor 1A 0.102
myl9 myosin, light polypeptide 9, regulatory 0.102
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Atg18 Autophagy-specific gene 18 0.998
Atg8a Autophagy-specific gene 8a 0.976
Rab7 Rab-protein 7 0.957
Rheb CG1081 gene product from transcript CG1081-RA 0.892
rpr reaper 0.796
RagA CG11968 gene product from transcript CG11968-RA 0.788
rl rolled 0.782
foxo forkhead box, sub-group O 0.764
bsk basket 0.724
gig gigas 0.687
CG11347 CG11347 gene product from transcript CG11347-RE 0.666
Vps16A Vacuolar protein sorting 16A 0.654
Atg2 Autophagy-specific gene 2 0.643
Atg6 Autophagy-specific gene 6 0.641
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.613
Syx17 Syntaxin 17 0.585
dm diminutive 0.560
Rab5 Rab-protein 5 0.544
hep hemipterous 0.509
CG3004 CG3004 gene product from transcript CG3004-RA 0.447
sd scalloped 0.441
bchs blue cheese 0.431
S6k RPS6-p70-protein kinase 0.427
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.424
Thor CG8846 gene product from transcript CG8846-RA 0.400
Sox14 Sox box protein 14 0.346
Pten CG5671 gene product from transcript CG5671-RB 0.343
Atg7 Autophagy-specific gene 7 0.333
p38b CG7393 gene product from transcript CG7393-RA 0.330
Rel Relish 0.328
Rfabg Retinoid- and fatty acid-binding glycoprotein 0.323
Akt1 CG4006 gene product from transcript CG4006-RA 0.312
p53 CG33336 gene product from transcript CG33336-RB 0.304
Csp Cysteine string protein 0.266
ird1 immune response deficient 1 0.250
Ptp61F Protein tyrosine phosphatase 61F 0.246
TBPH CG10327 gene product from transcript CG10327-RC 0.236
CG31033 CG31033 gene product from transcript CG31033-RC 0.223
Sir2 CG5216 gene product from transcript CG5216-RA 0.215
th thread 0.202
Ppcs Phosphopantothenoylcysteine synthetase 0.200
CG8709 CG8709 gene product from transcript CG8709-RK 0.192
CG5568 CG5568 gene product from transcript CG5568-RA 0.187
egr eiger 0.181
Tor Target of rapamycin 0.180
grim CG4345 gene product from transcript CG4345-RA 0.172
R Roughened 0.170
Syb Synaptobrevin 0.166
spin spinster 0.164
CG1347 CG1347 gene product from transcript CG1347-RB 0.161
Dcr-2 Dicer-2 0.148
trpml transient receptor potential mucolipin 0.146
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.142
Hcf Host cell factor 0.137
pan pangolin 0.136
CG7146 CG7146 gene product from transcript CG7146-RA 0.134
Atg9 Autophagy-specific gene 9 0.134
Mad Mothers against dpp 0.132
l(2)gl lethal (2) giant larvae 0.131
path pathetic 0.130
gnu giant nuclei 0.126
CYLD cylindromatosis 0.125
ci cubitus interruptus 0.124
CG10277 CG10277 gene product from transcript CG10277-RB 0.123
ari-1 ariadne 0.122
poly CG9829 gene product from transcript CG9829-RB 0.121
gammaSnap gamma-soluble NSF attachment protein 0.117
Vps36 Vacuolar protein sorting 36 0.116
dib disembodied 0.107
lt light 0.106
Pak3 CG14895 gene product from transcript CG14895-RA 0.105
H Hairless 0.105
klar klarsicht 0.104
Kr Kruppel 0.104
hk hook 0.102
Rab1 Rab-protein 1 0.101
imd immune deficiency 0.100
shd shade 0.096
Vti1 CG3279 gene product from transcript CG3279-RA 0.092
Dcp-1 Death caspase-1 0.089
Atg4 Autophagy-specific gene 4 0.087
amos absent MD neurons and olfactory sensilla 0.087
cathD CG1548 gene product from transcript CG1548-RA 0.085
Trx-2 thioredoxin-2 0.084
Ras85D Ras oncogene at 85D 0.083
CG11055 CG11055 gene product from transcript CG11055-RB 0.082
drpr draper 0.081
WASp CG1520 gene product from transcript CG1520-RA 0.081
klu klumpfuss 0.081
phl pole hole 0.080
twi twist 0.079
Sulf1 Sulfated 0.079
elav embryonic lethal abnormal vision 0.079
aop anterior open 0.078
Su(var)3-7 Suppressor of variegation 3-7 0.077
Vps26 Vacuolar protein sorting 26 0.077
stnB stoned B 0.075
Traf6 TNF-receptor-associated factor 6 0.074
g garnet 0.074
heix heixuedian 0.072
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SQSTM1 sequestosome 1 0.987
ATG3 ATG3 autophagy related 3 homolog (S. cerevisiae) 0.983
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.976
BECN1 beclin 1, autophagy related 0.943
ATG5 ATG5 autophagy related 5 homolog (S. cerevisiae) 0.931
CREBBP CREB binding protein 0.902
FKBP1A FK506 binding protein 1A, 12kDa 0.898
ATG12 ATG12 autophagy related 12 homolog (S. cerevisiae) 0.896
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.846
NCOR1 nuclear receptor corepressor 1 0.819
ATG13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.788
RB1CC1 RB1-inducible coiled-coil 1 0.787
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.763
KAT2B K(lysine) acetyltransferase 2B 0.761
SMAD2 SMAD family member 2 0.756
GABARAP GABA(A) receptor-associated protein 0.749
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.736
EP300 E1A binding protein p300 0.725
TP53 tumor protein p53 0.722
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.704
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.681
EGFR epidermal growth factor receptor 0.634
ESR1 estrogen receptor 1 0.633
SIRT1 sirtuin 1 0.625
ULK1 unc-51-like kinase 1 (C. elegans) 0.591
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.579
BCL2L1 BCL2-like 1 0.576
AR androgen receptor 0.551
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.533
MAPK8 mitogen-activated protein kinase 8 0.523
SP1 Sp1 transcription factor 0.520
SKIL SKI-like oncogene 0.502
INSR insulin receptor 0.489
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.485
NCOR2 nuclear receptor corepressor 2 0.480
TRIM63 tripartite motif containing 63 0.459
SMAD3 SMAD family member 3 0.458
CHMP1A chromatin modifying protein 1A 0.457
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.443
CAV1 caveolin 1, caveolae protein, 22kDa 0.442
DHCR7 7-dehydrocholesterol reductase 0.425
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.405
NCOA2 nuclear receptor coactivator 2 0.401
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.387
NFYA nuclear transcription factor Y, alpha 0.373
GSK3B glycogen synthase kinase 3 beta 0.368
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.367
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.364
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.323
TGFB1 transforming growth factor, beta 1 0.321
BMP2 bone morphogenetic protein 2 0.276
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.259
MAP2K1 mitogen-activated protein kinase kinase 1 0.259
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.244
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.243
AXL AXL receptor tyrosine kinase 0.240
SH3KBP1 SH3-domain kinase binding protein 1 0.235
MED10 mediator complex subunit 10 0.231
SNF8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.223
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.209
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.205
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.204
FOXO1 forkhead box O1 0.200
IRS2 insulin receptor substrate 2 0.197
HNF4A hepatocyte nuclear factor 4, alpha 0.193
MED13 mediator complex subunit 13 0.187
AMBRA1 autophagy/beclin-1 regulator 1 0.180
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.178
FBXW7 F-box and WD repeat domain containing 7 0.176
OTUB1 OTU domain, ubiquitin aldehyde binding 1 0.173
PDPK1 3-phosphoinositide dependent protein kinase-1 0.172
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.169
MAPK1 mitogen-activated protein kinase 1 0.168
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.168
MED15 mediator complex subunit 15 0.163
RHEB Ras homolog enriched in brain 0.156
ATF2 activating transcription factor 2 0.150
DSG2 desmoglein 2 0.150
AKT1S1 AKT1 substrate 1 (proline-rich) 0.149
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.148
IRS1 insulin receptor substrate 1 0.143
NCOA1 nuclear receptor coactivator 1 0.143
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.143
GFM1 G elongation factor, mitochondrial 1 0.137
SMAD4 SMAD family member 4 0.135
SMAD7 SMAD family member 7 0.135
PRKCA protein kinase C, alpha 0.135
PSEN1 presenilin 1 0.134
WWOX WW domain containing oxidoreductase 0.133
FOXO3 forkhead box O3 0.130
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.127
MED4 mediator complex subunit 4 0.127
ESR2 estrogen receptor 2 (ER beta) 0.126
ENO2 enolase 2 (gamma, neuronal) 0.125
PTEN phosphatase and tensin homolog 0.124
NCOA6 nuclear receptor coactivator 6 0.123
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.120
TP53BP2 tumor protein p53 binding protein, 2 0.120
SREBF2 sterol regulatory element binding transcription factor 2 0.119
ARID1B AT rich interactive domain 1B (SWI1-like) 0.117
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 0.999
Trp53 transformation related protein 53 0.993
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.983
Sqstm1 sequestosome 1 0.930
Bcl2 B-cell leukemia/lymphoma 2 0.887
Esr1 estrogen receptor 1 (alpha) 0.882
Pax8 paired box gene 8 0.864
Atg12 autophagy-related 12 (yeast) 0.859
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.830
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.686
Rb1 retinoblastoma 1 0.617
Ctnnb1 catenin (cadherin associated protein), beta 1 0.600
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.588
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.588
Nos3 nitric oxide synthase 3, endothelial cell 0.568
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.556
Fst follistatin 0.538
Lepr leptin receptor 0.504
Lrp1 low density lipoprotein receptor-related protein 1 0.492
Insr insulin receptor 0.475
Braf Braf transforming gene 0.461
Bglap bone gamma carboxyglutamate protein 0.453
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.431
Foxo1 forkhead box O1 0.430
Vdr vitamin D receptor 0.424
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.422
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.413
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.355
Wnt3a wingless-related MMTV integration site 3A 0.348
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.335
Foxc1 forkhead box C1 0.317
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.313
Ghr growth hormone receptor 0.308
Hif1a hypoxia inducible factor 1, alpha subunit 0.305
Ar androgen receptor 0.302
Kit kit oncogene 0.277
Atf2 activating transcription factor 2 0.276
Hbb-b1 hemoglobin, beta adult major chain 0.272
Slc12a1 solute carrier family 12, member 1 0.271
Arid1b AT rich interactive domain 1B (SWI-like) 0.264
Myod1 myogenic differentiation 1 0.253
Igh immunoglobulin heavy chain complex 0.248
Atp6v0b ATPase, H+ transporting, lysosomal V0 subunit B 0.239
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.228
Atg13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.226
Tecr trans-2,3-enoyl-CoA reductase 0.223
Flcn folliculin 0.213
Ulk1 Unc-51 like kinase 1 (C. elegans) 0.207
Mdm2 transformed mouse 3T3 cell double minute 2 0.194
Mecp2 methyl CpG binding protein 2 0.193
Grb10 growth factor receptor bound protein 10 0.191
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.183
Notch2 Notch gene homolog 2 (Drosophila) 0.182
Kl klotho 0.182
Mup19 major urinary protein 19 0.179
Myc myelocytomatosis oncogene 0.178
Dsg4 desmoglein 4 0.172
Notch1 Notch gene homolog 1 (Drosophila) 0.171
Gli3 GLI-Kruppel family member GLI3 0.168
Myf5 myogenic factor 5 0.167
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.166
Mup12 major urinary protein 12 0.165
Fshr follicle stimulating hormone receptor 0.163
Hprt hypoxanthine guanine phosphoribosyl transferase 0.161
Mup5 major urinary protein 5 0.161
Rptor regulatory associated protein of MTOR, complex 1 0.161
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.159
Ncoa6 nuclear receptor coactivator 6 0.158
Ahr aryl-hydrocarbon receptor 0.156
E2f1 E2F transcription factor 1 0.156
Foxa2 forkhead box A2 0.152
Foxo3 forkhead box O3 0.150
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.150
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.148
Fzd4 frizzled homolog 4 (Drosophila) 0.146
Prlr prolactin receptor 0.146
Msx1 homeobox, msh-like 1 0.143
Nos1 nitric oxide synthase 1, neuronal 0.143
Cbx1 chromobox homolog 1 (Drosophila HP1 beta) 0.142
Gata6 GATA binding protein 6 0.141
Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.140
Fos FBJ osteosarcoma oncogene 0.134
Wnt4 wingless-related MMTV integration site 4 0.132
Mup4 major urinary protein 4 0.132
Ccnd1 cyclin D1 0.131
Fzd8 frizzled homolog 8 (Drosophila) 0.131
Nf1 neurofibromatosis 1 0.130
Amhr2 anti-Mullerian hormone type 2 receptor 0.128
Lep leptin 0.128
Ubc ubiquitin C 0.128
Cd40 CD40 antigen 0.125
Tgfbr1 transforming growth factor, beta receptor I 0.125
Gabarap gamma-aminobutyric acid receptor associated protein 0.125
Mapk8 mitogen-activated protein kinase 8 0.124
Ift57 intraflagellar transport 57 homolog (Chlamydomonas) 0.123
Rora RAR-related orphan receptor alpha 0.122
Lmx1a LIM homeobox transcription factor 1 alpha 0.121
Krt15 keratin 15 0.121
Umod uromodulin 0.117
Wbp2 WW domain binding protein 2 0.116
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-EC2 RT1 class Ib, locus EC2 0.109
Syngr2 synaptogyrin 2 0.107
Col1a1 collagen, type I, alpha 1 0.098
Col1a2 collagen, type I, alpha 2 0.086
LOC100364500 RT1 class I, locus CE11-like 0.085
Reg3g regenerating islet-derived 3 gamma 0.078
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.077
Bgn biglycan 0.077
Col3a1 collagen, type III, alpha 1 0.076
Il1b interleukin 1 beta 0.069
Mmp12 matrix metallopeptidase 12 0.068
Ptprh protein tyrosine phosphatase, receptor type, H 0.065
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.064
Kcnh5 potassium voltage-gated channel, subfamily H (eag-related), member 5 0.060
Il1r2 interleukin 1 receptor, type II 0.052
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.049
Cd14 CD14 molecule 0.049
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.048
Arf5 ADP-ribosylation factor 5 0.047
Fis1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.047
Ccl2 chemokine (C-C motif) ligand 2 0.046
Postn periostin, osteoblast specific factor 0.046
Loxl1 lysyl oxidase-like 1 0.045
Ang1 angiogenin, ribonuclease A family, member 1 0.044
Orm1 orosomucoid 1 0.044
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.041
Cfp complement factor properdin 0.041
Omd osteomodulin 0.040
Col5a1 collagen, type V, alpha 1 0.040
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.040
Insl3 insulin-like 3 0.039
Chrnb2 cholinergic receptor, nicotinic, beta 2 (neuronal) 0.039
Hist1h1a histone cluster 1, H1a 0.039
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.039
Il6 interleukin 6 0.038
Il5 interleukin 5 0.038
Galnt5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 0.037
Tcrb T-cell receptor beta chain 0.037
Dcn decorin 0.036
Il8rb interleukin 8 receptor, beta 0.036
Cxcl10 chemokine (C-X-C motif) ligand 10 0.036
Gulo gulonolactone (L-) oxidase 0.035
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.035
Plau plasminogen activator, urokinase 0.035
Timp1 TIMP metallopeptidase inhibitor 1 0.035
Mmp7 matrix metallopeptidase 7 0.034
Cxcl2 chemokine (C-X-C motif) ligand 2 0.033
Gstm2 glutathione S-transferase mu 2 0.033
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.033
Oas1a 2'-5' oligoadenylate synthetase 1A 0.032
Ptgs2 prostaglandin-endoperoxide synthase 2 0.032
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.032
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.032
Rnf4 ring finger protein 4 0.031
Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) 0.031
RT1-S3 RT1 class Ib, locus S3 0.031
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.031
Txnrd1 thioredoxin reductase 1 0.031
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.030
Fasn fatty acid synthase 0.030
Il8ra interleukin 8 receptor, alpha 0.030
Mgst2 microsomal glutathione S-transferase 2 0.030
Obp3 alpha-2u globulin PGCL4 0.029
Ctsd cathepsin D 0.029
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.029
Calcb calcitonin-related polypeptide, beta 0.029
Usf1 upstream transcription factor 1 0.028
Map2k2 mitogen activated protein kinase kinase 2 0.028
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.028
Crip2 cysteine-rich protein 2 0.028
Gsr glutathione reductase 0.027
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.027
Htr2a 5-hydroxytryptamine (serotonin) receptor 2A 0.027
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.027
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.027
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.027
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.027
Svs1 seminal vesicle secretory protein 1 0.027
Eef2 eukaryotic translation elongation factor 2 0.027
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.027
Apoa1 apolipoprotein A-I 0.027
Sf3b1 splicing factor 3b, subunit 1 0.027
Prm3 protamine 3 0.026
Map1lc3b microtubule-associated protein 1 light chain 3 beta 0.026
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.026
Cd44 Cd44 molecule 0.026
Irf1 interferon regulatory factor 1 0.026
Rabac1 Rab acceptor 1 (prenylated) 0.026
Reg3a regenerating islet-derived 3 alpha 0.026
Egr2 early growth response 2 0.026
Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 0.026
Bcl2l1 Bcl2-like 1 0.026
Ephx1 epoxide hydrolase 1, microsomal 0.026
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.026
Stat6 signal transducer and activator of transcription 6 0.026
Plaa phospholipase A2, activating protein 0.026
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.026
Clca4 chloride channel accessory 4 0.026
Inhbe inhibin beta E 0.025
Mycs myc-like oncogene, s-myc protein 0.025