The network for 'reciprocal meiotic recombination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reciprocal meiotic recombination

The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SPO11 Spo11p 0.993
MSH4 Msh4p 0.978
RAD53 Rad53p 0.971
MEI4 Mei4p 0.948
MLH1 Mlh1p 0.937
RED1 Red1p 0.845
DMC1 Dmc1p 0.797
HOP1 Hop1p 0.762
ZIP1 Zip1p 0.744
RAD51 Rad51p 0.741
ECM11 Ecm11p 0.690
SPO22 Spo22p 0.687
MEI5 Mei5p 0.679
CSM4 Csm4p 0.646
SAE3 Sae3p 0.606
MEK1 Mek1p 0.530
RAD17 Rad17p 0.529
ZIP2 Zip2p 0.490
MUS81 Mus81p 0.471
CSM3 Csm3p 0.461
PCH2 Pch2p 0.442
REC8 Rec8p 0.425
RFA2 Rfa2p 0.423
MAM1 Mam1p 0.418
HFM1 Hfm1p 0.413
CST9 Cst9p 0.408
RFA1 Rfa1p 0.406
DDC1 Ddc1p 0.380
IME2 Ime2p 0.371
RAD55 Rad55p 0.297
MSH5 Msh5p 0.296
RAD54 Rad54p 0.289
REC114 Rec114p 0.271
YLR445W hypothetical protein 0.271
IRR1 Irr1p 0.264
PBP2 Pbp2p 0.242
YDL156W hypothetical protein 0.237
NDT80 Ndt80p 0.214
DUN1 Dun1p 0.208
PHO23 Pho23p 0.196
NDJ1 Ndj1p 0.195
MND1 Mnd1p 0.190
MDV1 Mdv1p 0.185
RAD27 Rad27p 0.176
PDS5 Pds5p 0.168
REC107 Rec107p 0.147
SPO13 Spo13p 0.145
IME4 Ime4p 0.137
AMA1 Ama1p 0.136
SRS2 Srs2p 0.135
MSH6 Msh6p 0.135
MRE11 Mre11p 0.134
CSM2 Csm2p 0.124
RAD52 Rad52p 0.117
REC102 Rec102p 0.113
HOP2 Hop2p 0.111
SEY1 Sey1p 0.110
RAD1 Rad1p 0.110
CPR1 Cpr1p 0.110
HHO1 Hho1p 0.109
MLH3 Mlh3p 0.101
CDC13 Cdc13p 0.099
PMS1 Pms1p 0.098
RAD5 Rad5p 0.097
RMI1 Rmi1p 0.094
DNA2 Dna2p 0.092
ACC1 Acc1p 0.090
CCT2 Cct2p 0.090
HOS4 Hos4p 0.090
CDC16 Cdc16p 0.086
RRN9 Rrn9p 0.084
SPO16 Spo16p 0.082
ASF1 Asf1p 0.080
VPS51 Vps51p 0.074
MAG2 Mag2p 0.072
SGS1 Sgs1p 0.070
RFA3 Rfa3p 0.070
CCT3 Cct3p 0.069
PSO2 Pso2p 0.069
BUD4 Bud4p 0.068
EST1 Est1p 0.066
MEC1 Mec1p 0.065
POL1 Pol1p 0.064
CIR2 Cir2p 0.062
RAD59 Rad59p 0.061
EIS1 Eis1p 0.059
CTM1 Ctm1p 0.059
RAD18 Rad18p 0.059
STB2 Stb2p 0.058
SLX4 Slx4p 0.056
MSH2 Msh2p 0.056
MLH2 Mlh2p 0.056
PFS1 Pfs1p 0.053
MCM4 Mcm4p 0.053
ECO1 Eco1p 0.052
STE4 Ste4p 0.052
YDR034W-B hypothetical protein 0.051
REC104 Rec104p 0.050
SWM2 Swm2p 0.050
OPT2 Opt2p 0.050
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
knl-1 Protein KNL-1 0.105
mcm-5 Protein MCM-5 0.066
bub-1 Protein BUB-1 0.042
mcm-7 Protein MCM-7 0.040
isw-1 Protein ISW-1 0.040
hcp-1 Protein HCP-1 0.039
cyk-4 Protein CYK-4 0.035
mcm-6 Protein MCM-6 0.032
ZC410.3 Protein ZC410.3 0.031
rod-1 Protein ROD-1 0.029
klp-19 Protein KLP-19 0.027
Y49F6B.9 Protein Y49F6B.9 0.026
mel-28 Protein MEL-28 0.023
rnr-1 Protein RNR-1 0.023
glp-1 Protein GLP-1 0.023
plk-3 Protein PLK-3 0.021
sdha-2 Protein SDHA-2 0.020
T07C4.3 Protein T07C4.3 0.020
C35D10.7 Protein C35D10.7 0.020
C28A5.1 Protein C28A5.1 0.019
mut-7 Protein MUT-7 0.019
rfc-4 Protein RFC-4 0.018
spd-2 Protein SPD-2 0.018
D1081.7 Protein D1081.7 0.017
CELE_F17C11.10 Protein F17C11.10 0.016
ima-2 Protein IMA-2 0.016
ufd-3 Protein UFD-3 0.016
dpl-1 Protein DPL-1 0.015
gld-3 Protein GLD-3 0.015
brd-1 Protein BRD-1 0.014
nasp-1 Protein NASP-1 0.014
klp-18 Protein KLP-18 0.014
nrde-1 Protein NRDE-1 0.014
rpa-1 Protein RPA-1 0.013
Y47D3A.29 Protein Y47D3A.29 0.013
npp-12 Protein NPP-12 0.013
dsh-2 Protein DSH-2 0.013
wago-9 Protein WAGO-9 0.013
scc-1 Protein SCC-1 0.013
zen-4 Protein ZEN-4 0.013
mcm-3 Protein MCM-3 0.013
lig-1 Protein LIG-1 0.013
bath-42 Protein BATH-42 0.013
ZK328.4 Protein ZK328.4 0.012
F56D2.2 Protein F56D2.2 0.012
cdl-1 Protein CDL-1 0.012
rha-1 Protein RHA-1 0.012
C35D10.6 Protein C35D10.6 0.012
bmk-1 Protein BMK-1 0.012
fzy-1 Protein FZY-1 0.012
smc-5 Protein SMC-5 0.011
wee-1.3 Protein WEE-1.3 0.011
mus-101 Protein MUS-101 0.011
glh-4 Protein GLH-4 0.010
F33H2.5 Protein F33H2.5 0.010
hcp-4 Protein HCP-4 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cdh1 cadherin 1, epithelial 0.601
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.529
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.499
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.293
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.262
esco2 establishment of cohesion 1 homolog 2 0.219
chaf1b chromatin assembly factor 1, subunit B 0.136
bactin1 bactin1 0.127
mybl2 myeloblastosis oncogene-like 2 0.122
pola2 polymerase (DNA directed), alpha 2 0.116
pola1 polymerase (DNA directed), alpha 1 0.112
wls wntless homolog (Drosophila) 0.094
zgc:158603 zgc:158603 0.077
fancl Fanconi anemia, complementation group L 0.071
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.065
npc1 Niemann-Pick disease, type C1 0.065
pinx1 pin2/trf1-interacting protein 1 0.064
top2a topoisomerase (DNA) II alpha 0.062
msh2 mutS homolog 2 (E. coli) 0.062
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.062
sass6 spindle assembly 6 homolog (C. elegans) 0.056
brca2 breast cancer 2, early onset 0.051
ptgs2a prostaglandin-endoperoxide synthase 2a 0.051
or111-10 odorant receptor, family D, subfamily 111, member 10 0.050
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.049
hells helicase, lymphoid-specific 0.048
foxi1 forkhead box I1 0.045
nup107 nucleoporin 107 0.044
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.044
smo smoothened homolog (Drosophila) 0.043
dnmt5 DNA (cytosine-5-)-methyltransferase 5 0.040
ahi1 Abelson helper integration site 1 0.039
aplp2 amyloid beta (A4) precursor-like protein 2 0.039
extl3 exostoses (multiple)-like 3 0.038
klf2a Kruppel-like factor 2a 0.037
zgc:100817 zgc:100817 0.037
dnmt7 DNA (cytosine-5-)-methyltransferase 7 0.036
psen1 presenilin 1 0.036
mcl1a myeloid cell leukemia sequence 1a 0.036
fzd7b frizzled homolog 7b 0.034
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.034
tert telomerase reverse transcriptase 0.034
igf1rb insulin-like growth factor 1b receptor 0.034
ahctf1 AT hook containing transcription factor 1 0.034
vasa vasa homolog 0.033
prim1 primase polypeptide 1 0.033
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.033
gpia glucose phosphate isomerase a 0.033
mych myelocytomatosis oncogene homolog 0.032
mapk14a mitogen-activated protein kinase 14a 0.032
trim33 tripartite motif-containing 33 0.032
pcna proliferating cell nuclear antigen 0.032
fgf8a fibroblast growth factor 8 a 0.032
smad5 MAD homolog 5 (Drosophila) 0.031
hirip3 HIRA interacting protein 3 0.031
dnmt3 DNA (cytosine-5-)-methyltransferase 3 0.030
slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 0.030
pbx4 pre-B-cell leukemia transcription factor 4 0.030
tk2 thymidine kinase 2, mitochondrial 0.029
hsd17b12a hydroxysteroid (17-beta) dehydrogenase 12a 0.027
cast calpastatin 0.027
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.027
rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.027
gdf11 growth differentiation factor 11 0.026
asf1bb ASF1 anti-silencing function 1 homolog Bb 0.026
brpf1 bromodomain and PHD finger containing, 1 0.026
pes pescadillo 0.025
LOC554173 abnormal spindles 0.025
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.025
prkci protein kinase C, iota 0.025
rfc1 replication factor C (activator 1) 1 0.025
kif23 kinesin family member 23 0.024
mapk3 mitogen-activated protein kinase 3 0.024
cpsf1 cleavage and polyadenylation specific factor 1 0.024
cbx2 chromobox homolog 2 (Drosophila Pc class) 0.024
piwil1 piwi-like 1 (Drosophila) 0.024
zbtb4 zinc finger and BTB domain containing 4 0.023
phox2b paired-like homeobox 2b 0.023
ung uracil-DNA glycosylase 0.023
bactin2 bactin2 0.023
tmem147 transmembrane protein 147 0.023
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.023
cdk2 cyclin-dependent kinase 2 0.023
tfe3b transcription factor binding to IGHM enhancer 3b 0.022
LOC100150924 DNA polymerase subunit gamma-1-like 0.022
eomesa eomesodermin homolog a 0.022
chek1 CHK1 checkpoint homolog (S. pombe) 0.022
ttk ttk protein kinase 0.022
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.022
csrnp1a cysteine-serine-rich nuclear protein 1a 0.022
ckap5 cytoskeleton associated protein 5 0.022
mbnl2 muscleblind-like 2 (Drosophila) 0.021
gdf6a growth differentiation factor 6a 0.021
ccnb1 cyclin B1 0.021
cdc45 CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.021
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.021
gro2 groucho 2 0.021
pold2 polymerase (DNA directed), delta 2, regulatory subunit 0.020
tbx1 T-box 1 0.020
ssrp1a structure specific recognition protein 1a 0.020
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
spn-A spindle A 1.000
spn-B spindle B 1.000
mei-9 meiotic 9 1.000
lok loki 0.989
c(3)G crossover suppressor on 3 of Gowen 0.961
nod no distributive disjunction 0.960
zwilch CG18729 gene product from transcript CG18729-RA 0.960
mus312 mutagen-sensitive 312 0.958
mus301 mutagen-sensitive 301 0.952
mus101 mutagen-sensitive 101 0.946
spn-D spindle D 0.944
mei-41 meiotic 41 0.941
okr okra 0.930
RecQ5 homolog of RecQ 0.920
ncd non-claret disjunctional 0.828
cort cortex 0.809
Brca2 Breast cancer 2, early onset homolog 0.749
Mcm5 Minichromosome maintenance 5 0.674
mei-218 meiotic 218 0.659
plu plutonium 0.583
mus205 mutagen-sensitive 205 0.564
CG5524 CG5524 gene product from transcript CG5524-RA 0.509
mei-217 CG33935 gene product from transcript CG33935-RC 0.504
hdm hold'em 0.466
Mcm3 Minichromosome maintenance 3 0.444
CG11403 CG11403 gene product from transcript CG11403-RA 0.418
sub subito 0.410
zuc zucchini 0.405
spn-E spindle E 0.386
CG7928 CG7928 gene product from transcript CG7928-RA 0.375
mus304 mutagen-sensitive 304 0.373
twe twine 0.371
Axs Abnormal X segregation 0.359
CG2662 CG2662 gene product from transcript CG2662-RA 0.349
lds lodestar 0.335
MAGE CG10059 gene product from transcript CG10059-RA 0.305
mus201 mutagen-sensitive 201 0.291
CG18271 CG18271 gene product from transcript CG18271-RB 0.284
mei-W68 meiotic W68 0.278
CDC45L CG3658 gene product from transcript CG3658-RA 0.266
asun asunder 0.238
trem trade embargo 0.237
CG11560 CG11560 gene product from transcript CG11560-RA 0.232
CG5199 CG5199 gene product from transcript CG5199-RA 0.229
Cks30A Cyclin-dependent kinase subunit 30A 0.189
ord orientation disruptor 0.184
Klp3A Kinesin-like protein at 3A 0.174
CG2617 CG2617 gene product from transcript CG2617-RA 0.167
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.164
rad50 CG6339 gene product from transcript CG6339-RD 0.161
CG4424 CG4424 gene product from transcript CG4424-RA 0.158
Cap-D3 Chromosome associated protein D3 0.156
png pan gu 0.155
Shc SHC-adaptor protein 0.154
Grip84 gamma-tubulin ring protein 84 0.135
spn-F CG12114 gene product from transcript CG12114-RA 0.128
ana2 anastral spindle 2 0.121
CG13367 CG13367 gene product from transcript CG13367-RA 0.111
CG11164 CG11164 gene product from transcript CG11164-RA 0.104
asp abnormal spindle 0.103
grau grauzone 0.103
CG11071 CG11071 gene product from transcript CG11071-RA 0.088
mei-P22 meiotic P22 0.085
Ercc1 CG10215 gene product from transcript CG10215-RA 0.082
cutlet CG33122 gene product from transcript CG33122-RA 0.082
mei-S332 meiotic from via Salaria 332 0.075
DNApol-alpha60 DNA polymerase alpha 60kD 0.074
CG14561 CG14561 gene product from transcript CG14561-RA 0.070
alph alphabet 0.065
l(2)05714 lethal (2) 05714 0.062
Caf1-105 CG12892 gene product from transcript CG12892-RA 0.060
armi armitage 0.056
CG2712 CG2712 gene product from transcript CG2712-RA 0.056
CG10336 CG10336 gene product from transcript CG10336-RC 0.055
CG8079 CG8079 gene product from transcript CG8079-RA 0.053
prod proliferation disrupter 0.053
CG17361 CG17361 gene product from transcript CG17361-RA 0.049
CG17802 CG17802 gene product from transcript CG17802-RA 0.049
CG7239 CG7239 gene product from transcript CG7239-RA 0.048
CG7053 CG7053 gene product from transcript CG7053-RA 0.045
ranshi CG9793 gene product from transcript CG9793-RA 0.045
mus308 mutagen-sensitive 308 0.043
CG14220 CG14220 gene product from transcript CG14220-RA 0.042
CG7183 CG7183 gene product from transcript CG7183-RA 0.041
nudE CG8104 gene product from transcript CG8104-RB 0.040
can cannonball 0.040
Smc5 CG32438 gene product from transcript CG32438-RE 0.039
c(2)M crossover suppressor on 2 of Manheim 0.037
CG8478 CG8478 gene product from transcript CG8478-RD 0.036
CG15601 CG15601 gene product from transcript CG15601-RA 0.036
orb oo18 RNA-binding protein 0.035
fs(1)Ya female sterile (1) Young arrest 0.035
CycC Cyclin C 0.034
dah discontinuous actin hexagon 0.034
CG7824 CG7824 gene product from transcript CG7824-RC 0.033
gammaTub37C gamma-Tubulin at 37C 0.032
az2 CG1605 gene product from transcript CG1605-RA 0.032
Mcm7 Minichromosome maintenance 7 0.031
CG7745 CG7745 gene product from transcript CG7745-RA 0.031
CG16734 CG16734 gene product from transcript CG16734-RD 0.031
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RPA1 replication protein A1, 70kDa 1.000
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.999
RPA3 replication protein A3, 14kDa 0.963
BRCA1 breast cancer 1, early onset 0.952
RFC1 replication factor C (activator 1) 1, 145kDa 0.951
BLM Bloom syndrome, RecQ helicase-like 0.910
APITD1 apoptosis-inducing, TAF9-like domain 1 0.908
PDS5B PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.854
BRCA2 breast cancer 2, early onset 0.850
MCM6 minichromosome maintenance complex component 6 0.804
MSH5 mutS homolog 5 (E. coli) 0.737
RPA2 replication protein A2, 32kDa 0.728
RFC2 replication factor C (activator 1) 2, 40kDa 0.719
RFC4 replication factor C (activator 1) 4, 37kDa 0.678
MSH4 mutS homolog 4 (E. coli) 0.633
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.623
RFC3 replication factor C (activator 1) 3, 38kDa 0.608
WRN Werner syndrome, RecQ helicase-like 0.565
MDC1 mediator of DNA-damage checkpoint 1 0.542
PCNA proliferating cell nuclear antigen 0.510
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.510
MCMBP minichromosome maintenance complex binding protein 0.501
RAD50 RAD50 homolog (S. cerevisiae) 0.443
RAD18 RAD18 homolog (S. cerevisiae) 0.373
FANCB Fanconi anemia, complementation group B 0.301
MCM4 minichromosome maintenance complex component 4 0.295
RAD21 RAD21 homolog (S. pombe) 0.256
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.236
ORC3 origin recognition complex, subunit 3 0.224
SMC1A structural maintenance of chromosomes 1A 0.207
MCM3 minichromosome maintenance complex component 3 0.201
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.193
MCM2 minichromosome maintenance complex component 2 0.169
NBN nibrin 0.163
FANCD2 Fanconi anemia, complementation group D2 0.154
STRA13 stimulated by retinoic acid 13 homolog (mouse) 0.144
FANCM Fanconi anemia, complementation group M 0.136
RAD51L3 RAD51-like 3 (S. cerevisiae) 0.120
RAD51AP1 RAD51 associated protein 1 0.100
MSH6 mutS homolog 6 (E. coli) 0.097
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.094
PRC1 protein regulator of cytokinesis 1 0.090
DSCC1 defective in sister chromatid cohesion 1 homolog (S. cerevisiae) 0.087
HLTF helicase-like transcription factor 0.084
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.081
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.076
NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 0.075
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.070
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.066
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.066
RAD9A RAD9 homolog A (S. pombe) 0.066
ORC1 origin recognition complex, subunit 1 0.062
RMI1 RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) 0.061
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.061
MCM7 minichromosome maintenance complex component 7 0.061
ORC6 origin recognition complex, subunit 6 0.061
RAD52 RAD52 homolog (S. cerevisiae) 0.060
PALB2 partner and localizer of BRCA2 0.060
SYCP3 synaptonemal complex protein 3 0.056
PRNP prion protein 0.053
FANCG Fanconi anemia, complementation group G 0.049
ATM ataxia telangiectasia mutated 0.048
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.048
DMC1 DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) 0.048
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.047
TERF2 telomeric repeat binding factor 2 0.046
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.044
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.043
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.042
RAD54B RAD54 homolog B (S. cerevisiae) 0.042
CENPE centromere protein E, 312kDa 0.039
H2AFX H2A histone family, member X 0.036
C19orf39 chromosome 19 open reading frame 39 0.036
FANCA Fanconi anemia, complementation group A 0.036
KNTC1 kinetochore associated 1 0.032
RIF1 RAP1 interacting factor homolog (yeast) 0.031
CENPM centromere protein M 0.031
CLIP1 CAP-GLY domain containing linker protein 1 0.031
TPR translocated promoter region (to activated MET oncogene) 0.030
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.029
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.029
RNF20 ring finger protein 20 0.028
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.028
ZNF337 zinc finger protein 337 0.028
C16orf75 chromosome 16 open reading frame 75 0.027
ZNF133 zinc finger protein 133 0.027
MSH3 mutS homolog 3 (E. coli) 0.027
DCTPP1 dCTP pyrophosphatase 1 0.026
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.025
DTL denticleless homolog (Drosophila) 0.024
KIF20B kinesin family member 20B 0.024
TMEM106C transmembrane protein 106C 0.024
RNASEH2A ribonuclease H2, subunit A 0.023
PTTG1 pituitary tumor-transforming 1 0.023
CENPW centromere protein W 0.023
TOP3A topoisomerase (DNA) III alpha 0.023
RRM1 ribonucleotide reductase M1 0.022
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.022
PARP1 poly (ADP-ribose) polymerase 1 0.021
SNF8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.021
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Brca1 breast cancer 1 0.982
Brca2 breast cancer 2 0.917
Pten phosphatase and tensin homolog 0.664
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.515
Cdca5 cell division cycle associated 5 0.499
Nde1 nuclear distribution gene E homolog 1 (A nidulans) 0.304
Kif22 kinesin family member 22 0.191
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.170
Exo1 exonuclease 1 0.168
Trp53 transformation related protein 53 0.167
Nup85 nucleoporin 85 0.153
Smc1a structural maintenance of chromosomes 1A 0.134
Ctnnb1 catenin (cadherin associated protein), beta 1 0.128
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.103
Plk1 polo-like kinase 1 (Drosophila) 0.097
Mybl2 myeloblastosis oncogene-like 2 0.094
Mdm4 transformed mouse 3T3 cell double minute 4 0.093
Prim1 DNA primase, p49 subunit 0.090
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.089
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.087
Hells helicase, lymphoid specific 0.081
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.079
Rrm1 ribonucleotide reductase M1 0.077
Lig1 ligase I, DNA, ATP-dependent 0.076
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.071
Ccne1 cyclin E1 0.070
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.070
Ccnf cyclin F 0.065
Atm ataxia telangiectasia mutated homolog (human) 0.064
Tacc3 transforming, acidic coiled-coil containing protein 3 0.058
Rfc1 replication factor C (activator 1) 1 0.058
Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) 0.057
Sgol1 shugoshin-like 1 (S. pombe) 0.057
Pms2 postmeiotic segregation increased 2 (S. cerevisiae) 0.055
Emx1 empty spiracles homolog 1 (Drosophila) 0.054
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.054
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.051
Orc1 origin recognition complex, subunit 1 0.050
Nbn nibrin 0.050
Blm Bloom syndrome, RecQ helicase-like 0.050
Kif23 kinesin family member 23 0.050
Aurka aurora kinase A 0.048
Rad51ap1 RAD51 associated protein 1 0.048
Ccna2 cyclin A2 0.048
Bard1 BRCA1 associated RING domain 1 0.047
Ttk Ttk protein kinase 0.047
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.047
Fen1 flap structure specific endonuclease 1 0.045
Prc1 protein regulator of cytokinesis 1 0.044
Kif11 kinesin family member 11 0.044
Gtse1 G two S phase expressed protein 1 0.044
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.042
Aurkb aurora kinase B 0.042
Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.042
Ncaph non-SMC condensin I complex, subunit H 0.041
Prim2 DNA primase, p58 subunit 0.041
Fam54a family with sequence similarity 54, member A 0.041
Trp73 transformation related protein 73 0.040
Smc2 structural maintenance of chromosomes 2 0.040
Kif2c kinesin family member 2C 0.038
Apc adenomatosis polyposis coli 0.037
Kif20a kinesin family member 20A 0.036
Trp63 transformation related protein 63 0.036
Mecp2 methyl CpG binding protein 2 0.035
Dtl denticleless homolog (Drosophila) 0.035
Cdc7 cell division cycle 7 (S. cerevisiae) 0.035
Ccnb1 cyclin B1 0.035
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.034
Cdk1 cyclin-dependent kinase 1 0.034
Nxf2 nuclear RNA export factor 2 0.034
Cdc45 cell division cycle 45 homolog (S. cerevisiae) 0.034
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.033
Gins1 GINS complex subunit 1 (Psf1 homolog) 0.033
Tcf19 transcription factor 19 0.033
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.031
Dhfr dihydrofolate reductase 0.031
Rfc4 replication factor C (activator 1) 4 0.030
Cenph centromere protein H 0.030
E2f1 E2F transcription factor 1 0.029
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.029
Iqgap3 IQ motif containing GTPase activating protein 3 0.028
Bub1 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) 0.028
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.027
Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein 0.027
Stil Scl/Tal1 interrupting locus 0.026
Ckap2 cytoskeleton associated protein 2 0.025
Spag5 sperm associated antigen 5 0.025
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.023
Incenp inner centromere protein 0.023
Mis18bp1 MIS18 binding protein 1 0.023
Mdm2 transformed mouse 3T3 cell double minute 2 0.023
Phf5a PHD finger protein 5A 0.022
Cenpn centromere protein N 0.022
Pola1 polymerase (DNA directed), alpha 1 0.022
Sass6 spindle assembly 6 homolog (C. elegans) 0.021
Sfn stratifin 0.020
Pask PAS domain containing serine/threonine kinase 0.020
Racgap1 Rac GTPase-activating protein 1 0.020
Smc1b structural maintenance of chromosomes 1B 0.020
Mcm10 minichromosome maintenance deficient 10 (S. cerevisiae) 0.019
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Rattus norvegicus
Name Description Probability Func Analog Organism