The network for 'cellular response to calcium ion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to calcium ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.

Name Description Probability Func Analog Organism
MIG2 Mig2p 0.388
NRG1 Nrg1p 0.231
HXT3 Hxt3p 0.207
YPL014W hypothetical protein 0.196
RLM1 Rlm1p 0.190
POG1 Pog1p 0.177
TPO2 Tpo2p 0.161
MBR1 Mbr1p 0.142
ZAP1 Zap1p 0.131
SMP1 Smp1p 0.122
ROX1 Rox1p 0.117
MIG1 Mig1p 0.116
KIC1 Kic1p 0.114
HAL5 Hal5p 0.110
RGS2 Rgs2p 0.108
TRA1 Tra1p 0.106
YPR157W hypothetical protein 0.103
YKR075C hypothetical protein 0.099
VID24 Vid24p 0.098
CAT8 Cat8p 0.095
HST3 Hst3p 0.094
MIG3 Mig3p 0.093
CRZ1 Crz1p 0.088
TYE7 Tye7p 0.087
YPL088W hypothetical protein 0.075
MOB1 Mob1p 0.074
RIM101 Rim101p 0.071
YRO2 Yro2p 0.071
RSC9 Rsc9p 0.070
SKS1 Sks1p 0.070
YNR014W hypothetical protein 0.069
ACA1 Aca1p 0.068
DAL81 Dal81p 0.066
CUP9 Cup9p 0.066
YLR297W hypothetical protein 0.065
EAR1 Ear1p 0.061
PUT4 Put4p 0.059
ICS2 Ics2p 0.059
YKL187C hypothetical protein 0.058
HSF1 Hsf1p 0.057
STL1 Stl1p 0.056
GAT2 Gat2p 0.055
MOT3 Mot3p 0.054
IRC23 Irc23p 0.054
FAA2 Faa2p 0.052
PMD1 Pmd1p 0.051
SRD1 Srd1p 0.051
VAC7 Vac7p 0.050
YNL234W hypothetical protein 0.049
SSK2 Ssk2p 0.047
YPR013C hypothetical protein 0.046
LEU2 Leu2p 0.046
YAR068W hypothetical protein 0.045
TBS1 Tbs1p 0.044
NDD1 Ndd1p 0.044
GLN3 Gln3p 0.043
HDA2 Hda2p 0.043
ARP10 Arp10p 0.042
YLR264C-A hypothetical protein 0.042
STP2 Stp2p 0.041
RPI1 Rpi1p 0.041
TOS8 Tos8p 0.041
RMA1 Rma1p 0.041
ATF1 Atf1p 0.040
HXT1 Hxt1p 0.040
YOL038C-A hypothetical protein 0.040
TIP1 Tip1p 0.040
ROG3 Rog3p 0.040
PRR2 Prr2p 0.040
HOR2 Hor2p 0.039
YOR385W hypothetical protein 0.039
YER034W hypothetical protein 0.039
PHM8 Phm8p 0.038
GIS3 Gis3p 0.038
YLR162W hypothetical protein 0.038
PCL2 Pcl2p 0.038
YIR035C hypothetical protein 0.038
ICY1 Icy1p 0.037
YAT1 Yat1p 0.037
CBK1 Cbk1p 0.037
HOT1 Hot1p 0.036
HMS1 Hms1p 0.036
PHO12 Pho12p 0.036
MCH5 Mch5p 0.036
SPS4 Sps4p 0.035
HAA1 Haa1p 0.035
ADH2 Adh2p 0.035
AUA1 Aua1p 0.034
MER1 Mer1p 0.034
YAR066W hypothetical protein 0.034
RMD8 Rmd8p 0.034
CUP1-1 Cup1-1p 0.034
TOS3 Tos3p 0.034
FMT1 Fmt1p 0.034
ALD4 Ald4p 0.034
YBR013C hypothetical protein 0.033
ZPS1 Zps1p 0.033
KRE29 Kre29p 0.033
ATP6 Atp6p 0.033
SSU1 Ssu1p 0.033
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.992
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.933
HDAC4 histone deacetylase 4 0.932
COTL1 coactosin-like 1 (Dictyostelium) 0.663
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.616
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.355
IER2 immediate early response 2 0.260
JUND jun D proto-oncogene 0.245
ATF3 activating transcription factor 3 0.244
SNTG2 syntrophin, gamma 2 0.199
HDAC9 histone deacetylase 9 0.185
TTN titin 0.184
FOS FBJ murine osteosarcoma viral oncogene homolog 0.138
MAPK14 mitogen-activated protein kinase 14 0.137
JUNB jun B proto-oncogene 0.127
PTCHD2 patched domain containing 2 0.125
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.123
MAP2K1 mitogen-activated protein kinase kinase 1 0.117
NEB nebulin 0.084
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 0.075
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.074
BTG2 BTG family, member 2 0.050
HMG20A high mobility group 20A 0.048
JUN jun proto-oncogene 0.046
PRKCE protein kinase C, epsilon 0.044
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.043
LRRK2 leucine-rich repeat kinase 2 0.036
KIF23 kinesin family member 23 0.034
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.034
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.031
KRT5 keratin 5 0.030
NCF2 neutrophil cytosolic factor 2 0.027
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 0.026
FKBP4 FK506 binding protein 4, 59kDa 0.025
FZD1 frizzled homolog 1 (Drosophila) 0.025
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.025
LRP6 low density lipoprotein receptor-related protein 6 0.024
FOSL1 FOS-like antigen 1 0.024
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.022
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.022
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.021
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.018
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.018
PER1 period homolog 1 (Drosophila) 0.018
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.018
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.017
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.017
SLC9A1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.017
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.017
KLF4 Kruppel-like factor 4 (gut) 0.017
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.017
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.016
RAP1A RAP1A, member of RAS oncogene family 0.016
ADAM9 ADAM metallopeptidase domain 9 0.016
SIAH1 seven in absentia homolog 1 (Drosophila) 0.016
SEPT10 septin 10 0.016
FOSL2 FOS-like antigen 2 0.016
MEF2A myocyte enhancer factor 2A 0.016
KDM6B lysine (K)-specific demethylase 6B 0.016
LSM1 LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.015
DUSP1 dual specificity phosphatase 1 0.015
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.015
TWSG1 twisted gastrulation homolog 1 (Drosophila) 0.014
ATF2 activating transcription factor 2 0.014
TRIP10 thyroid hormone receptor interactor 10 0.014
RAI1 retinoic acid induced 1 0.014
RHOB ras homolog gene family, member B 0.013
EGR1 early growth response 1 0.013
KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.013
RASA4B RAS p21 protein activator 4B 0.013
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.013
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.013
MAPK3 mitogen-activated protein kinase 3 0.012
ANXA2 annexin A2 0.012
WASL Wiskott-Aldrich syndrome-like 0.012
IQGAP1 IQ motif containing GTPase activating protein 1 0.012
TXN thioredoxin 0.012
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.012
LGALS1 lectin, galactoside-binding, soluble, 1 0.012
ASS1 argininosuccinate synthase 1 0.012
JDP2 Jun dimerization protein 2 0.012
CALU calumenin 0.011
SPTBN1 spectrin, beta, non-erythrocytic 1 0.010
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.010
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.010
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.010
MEF2C myocyte enhancer factor 2C 0.010
TSC22D3 TSC22 domain family, member 3 0.010
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Neurod1 neurogenic differentiation 1 0.984
Fos FBJ osteosarcoma oncogene 0.953
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.898
Pax6 paired box gene 6 0.820
Neurog2 neurogenin 2 0.781
Klf6 Kruppel-like factor 6 0.695
Dusp1 dual specificity phosphatase 1 0.694
Krt8 keratin 8 0.676
Otx2 orthodenticle homolog 2 (Drosophila) 0.660
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.559
Btg2 B-cell translocation gene 2, anti-proliferative 0.541
Shh sonic hedgehog 0.534
Isl1 ISL1 transcription factor, LIM/homeodomain 0.513
Krt7 keratin 7 0.510
Zfp36 zinc finger protein 36 0.383
Mef2c myocyte enhancer factor 2C 0.368
Atoh7 atonal homolog 7 (Drosophila) 0.365
Pitx1 paired-like homeodomain transcription factor 1 0.313
Mecom MDS1 and EVI1 complex locus 0.300
Jun Jun oncogene 0.300
Egr1 early growth response 1 0.292
Onecut1 one cut domain, family member 1 0.268
Krt5 keratin 5 0.263
Nhlh1 nescient helix loop helix 1 0.247
Krt14 keratin 14 0.244
Neurod4 neurogenic differentiation 4 0.242
Krt17 keratin 17 0.241
Hdac4 histone deacetylase 4 0.236
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.225
Ptf1a pancreas specific transcription factor, 1a 0.223
Dlx3 distal-less homeobox 3 0.198
Tcfap2a transcription factor AP-2, alpha 0.192
Hand1 heart and neural crest derivatives expressed transcript 1 0.171
Mapk8 mitogen-activated protein kinase 8 0.158
Alox5 arachidonate 5-lipoxygenase 0.156
Lhx5 LIM homeobox protein 5 0.155
Omp olfactory marker protein 0.153
Ldb3 LIM domain binding 3 0.144
En1 engrailed 1 0.143
Rhob ras homolog gene family, member B 0.143
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.137
Krt19 keratin 19 0.132
Cbfa2t3 core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) 0.126
Shox2 short stature homeobox 2 0.110
Krt20 keratin 20 0.109
Gpr50 G-protein-coupled receptor 50 0.106
Egr2 early growth response 2 0.099
Sox11 SRY-box containing gene 11 0.098
Sprr1a small proline-rich protein 1A 0.096
Gdf11 growth differentiation factor 11 0.094
Edn2 endothelin 2 0.092
Nfatc4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.091
Phlda2 pleckstrin homology-like domain, family A, member 2 0.090
Myf5 myogenic factor 5 0.089
Krt71 keratin 71 0.087
Hoxd13 homeobox D13 0.086
Lgr5 leucine rich repeat containing G protein coupled receptor 5 0.086
Cldn4 claudin 4 0.084
Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) 0.084
Prph2 peripherin 2 0.084
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.081
Klf4 Kruppel-like factor 4 (gut) 0.080
Foxc2 forkhead box C2 0.075
Lmo2 LIM domain only 2 0.072
Lhx3 LIM homeobox protein 3 0.072
Hdac7 histone deacetylase 7 0.071
Gata1 GATA binding protein 1 0.071
Rb1 retinoblastoma 1 0.070
Pdx1 pancreatic and duodenal homeobox 1 0.069
Psapl1 prosaposin-like 1 0.068
Atf3 activating transcription factor 3 0.068
Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.067
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.067
Msx2 homeobox, msh-like 2 0.066
Notch4 Notch gene homolog 4 (Drosophila) 0.066
Fgf6 fibroblast growth factor 6 0.066
Lims1 LIM and senescent cell antigen-like domains 1 0.065
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.064
Gsc goosecoid homeobox 0.063
Cckbr cholecystokinin B receptor 0.063
Eda ectodysplasin-A 0.062
Nfatc3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.062
Sfn stratifin 0.062
Krt86 keratin 86 0.060
Alox8 arachidonate 8-lipoxygenase 0.060
Vcl vinculin 0.058
Srpk3 serine/arginine-rich protein specific kinase 3 0.058
Dlx1 distal-less homeobox 1 0.058
Myadm myeloid-associated differentiation marker 0.056
Ptms parathymosin 0.054
Fosb FBJ osteosarcoma oncogene B 0.054
Elf3 E74-like factor 3 0.052
Ppl periplakin 0.052
Krt36 keratin 36 0.052
Gnb3 guanine nucleotide binding protein (G protein), beta 3 0.051
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.050
Msx1 homeobox, msh-like 1 0.050
Mef2d myocyte enhancer factor 2D 0.049
Nfil3 nuclear factor, interleukin 3, regulated 0.049
Hr hairless 0.049
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Rattus norvegicus
Name Description Probability Func Analog Organism